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| # | Title | Abstract | Journal | Language | Year | Month | Authors | Affiliations | Name | Abbr Name | ISSN | EISSN | Impact_Factor | Impact_Factor_5Years | Journal_Category | Universities | Study_Type_Extracted | Standardized_University | University | Rank | Research_Score | |
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| 1 | 0 | corrigendum to "consensus report on glucagon-like peptide-1 receptor agonists as adjunctive treatment for individuals with type 1 diabetes using an automated insulin delivery system". | no abstract | journal of diabetes science and technology | eng | 2024 | Nov | journal of diabetes science and technology | j diabetes sci techn | 1932-2968 | 1932-2968 | 4.1 | ENDOCRINOLOGY & METABOLISM|Q2|49/186 | Unknown | Unknown | unknown | ||||||
| 2 | 1 | human primary macrophages can transmit coxsackie b4 virus to pancreatic cells in vitro. | no abstract | journal of medical virology | eng | 2024 | Dec | Brisse Morgan, Ly Hinh | viral immunity and pathogenesis unit, laboratory of viral diseases, national institute of allergy and infectious diseases (niaid), national institutes of health (nih), bethesda, maryland, usa., department of veterinary and biomedical sciences, college of veterinary medicine, university of minnesota, twin cities, minnesota, usa. | journal of medical virology | j med virol | 0146-6615 | 1096-9071 | 6.8 | 6.6 | VIROLOGY|Q1|4/41 | national institute of allergy and infectious diseases (niaid), national institutes of health, nih, department of veterinary and biomedical sciences, college of veterinary medicine, university of minnesota | Unknown | national institute | |||
| 3 | 2 | association between insulin-associated gene polymorphisms and new-onset diabetes mellitus in statin-treated patients. | while statins are effective at managing lipid levels, there is growing evidence for new-onset diabetes mellitus (nodm). the insulin signalling pathway (isp) inhibited by statins is one of the potential mechanisms; however, most studies have been limited to in vitro settings. therefore, this study aimed to identify the genetic associations within the isp-related genes and nodm. | european journal of clinical investigation | eng | 2024 | Nov | Park Minju, Kim Jung Sun, Park Yoon-A, Lee Da Hoon, Choi Seo-A, Chang Yoonkyung, Song Tae-Jin, Gwak Hye Sun, Yee Jeong | college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, seoul, south korea., college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, seoul, south korea., college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, seoul, south korea., college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, seoul, south korea., college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, seoul, south korea., department of neurology, ewha womans university mokdong hospital, ewha womans university college of medicine, seoul, south korea., department of neurology, ewha womans university seoul hospital, ewha womans university college of medicine, seoul, south korea., college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, seoul, south korea., school of pharmacy, sungkyunkwan university, suwon, south korea. | european journal of clinical investigation | eur j clin invest | 0014-2972 | 1365-2362 | 4.4 | 4.7 | MEDICINE, RESEARCH & EXPERIMENTAL|Q2|57/189 | college of pharmacy, ewha womans university, college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, college of pharmacy, ewha womans university, college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, ewha womans university, ewha womans university, ewha womans university, ewha womans university, college of pharmacy and graduate school of pharmaceutical sciences, ewha womans university, school of pharmacy, sungkyunkwan university | Unknown | womans university | |||
| 4 | 3 | improvement of glycemia risk index and continuous glucose monitoring metrics during ramadan fasting in type 1 diabetes: a real-world observational study. | managing glycemia during ramadan is challenging for individuals with type 1 diabetes (t1d) due to prolonged fasting and altered eating patterns. while many are exempt from fasting, some choose to fast, necessitating careful monitoring. the glycemia risk index (gri) is valuable for assessing glycemic quality and interpreting continuous glucose monitoring (cgm) data to identify individuals needing closer clinical attention. this study investigates the effects of ramadan fasting on glycemic control in t1d, focusing on gri and its components for hypoglycemia (chypo) and hyperglycemia (chyper). | journal of diabetes science and technology | eng | 2024 | Nov | Al Hayek Ayman, Al Dawish Mohamed A | department of endocrinology and diabetes, diabetes treatment center, prince sultan military medical city, riyadh, saudi arabia., department of endocrinology and diabetes, diabetes treatment center, prince sultan military medical city, riyadh, saudi arabia. | journal of diabetes science and technology | j diabetes sci techn | 1932-2968 | 1932-2968 | 4.1 | ENDOCRINOLOGY & METABOLISM|Q2|49/186 | department of endocrinology and diabetes, diabetes treatment center, prince sultan military medical city, department of endocrinology and diabetes, diabetes treatment center, prince sultan military medical city | Unknown | unknown | ||||
| 5 | 4 | transmucosal glucagon rapidly increases blood glucose concentration in healthy cats. | to evaluate the effect of transmucosal glucagon powder (baqsimi; amphastar pharmaceuticals) on blood glucose (bg) concentrations in healthy cats and describe adverse reactions to its administration. | journal of feline medicine and surgery | eng | 2024 | Nov | Cohen Emily A, Porter Lauren, Crews Chiquitha D, Mott Jocelyn, Tardo Antonio M, Gilor Chen | department of small animal clinical sciences, university of florida, college of veterinary medicine, gainesville, fl, usa., department of small animal clinical sciences, university of florida, college of veterinary medicine, gainesville, fl, usa., department of small animal clinical sciences, university of florida, college of veterinary medicine, gainesville, fl, usa., department of small animal clinical sciences, university of florida, college of veterinary medicine, gainesville, fl, usa., department of veterinary medical sciences, university of bologna, ozzano dell'emilia, italy., department of small animal clinical sciences, university of florida, college of veterinary medicine, gainesville, fl, usa. | journal of feline medicine and surgery | j feline med surg | 1098-612X | 1532-2750 | 1.9 | 2.0 | VETERINARY SCIENCES|Q2|46/167 | university of florida, college of veterinary medicine, university of florida, college of veterinary medicine, university of florida, college of veterinary medicine, university of florida, college of veterinary medicine, university of bologna, university of florida, college of veterinary medicine | Unknown | unknown | |||
| 6 | 5 | decoding the synergy: unveiling gradient boosting regression model for multivariate quantitation of pioglitazone, alogliptin and glimepiride in pure and tablet dosage forms. | this study represents a comparison among the performances of four multivariate procedures: partial least square (pls) and artificial neural networks (ann) in addition to support vector regression (svr) and extreme gradient boosting (xg boost) algorithm for the determination of the anti-diabetic mixture of pioglitazone (pio), alogliptin (alg) and glimepiride (glm) in pharmaceutical formulations with aid of uv spectrometry. key wavelengths were selected using knowledge-based variable selection and various preprocessing methods (e.g., mean centering, orthogonal scatter correction, and principal component analysis) to minimize noise and improve model precision. xg boost effectively enhanced computing speed and accuracy by focusing on specific spectral features rather than the entire spectrum, demonstrating its advantages in resolving complex, overlapping spectral data. the independent test results of different models demonstrated that xg boost outperformed other methods. xg boost achieved the lowest root mean squared error of prediction (rmsep) and standard deviation (sd) values across all compounds, indicating minimal prediction error and variability. for pio, xg boost recorded an rmsep of 0.100 and sd of 0.369, significantly better than pls and ann. for alg, xg boost showed near-perfect performance with an rmsep of 0.001 and sd of 0.005, outperforming svr and pls, which had higher error rates. in the case of glm, xg boost also excelled with an rmsep of 0.001 and sd of 0.018, demonstrating superior precision compared to the much higher errors seen in pls and ann. these results highlight xg boost's exceptional ability to handle complex, overlapping spectral data, making it the most reliable and accurate model in this study. | bmc chemistry | eng | 2024 | Nov | Elkhoudary Mahmoud M, Marie Aya A, Hammad Sherin F, Salim Mohamed M, Kamal Amira H | department of pharmaceutical chemistry, faculty of pharmacy, horus university-egypt, new damietta, 34517, egypt., department of pharmaceutical chemistry, faculty of pharmacy, horus university-egypt, new damietta, 34517, egypt., department of pharmaceutical analytical chemistry, faculty of pharmacy, tanta university, tanta, 31527, egypt., department of pharmaceutical chemistry, faculty of pharmacy, horus university-egypt, new damietta, 34517, egypt., department of pharmaceutical analytical chemistry, faculty of pharmacy, tanta university, tanta, 31527, egypt. amira.saad@pharm.tanta.edu.eg. | bmc chemistry | bmc chem | 2661-801X | 4.3 | 4.4 | CHEMISTRY, MULTIDISCIPLINARY|Q2|71/230 | department of pharmaceutical chemistry, faculty of pharmacy, horus university-egypt, department of pharmaceutical chemistry, faculty of pharmacy, horus university-egypt, department of pharmaceutical analytical chemistry, faculty of pharmacy, tanta university, department of pharmaceutical chemistry, faculty of pharmacy, horus university-egypt, department of pharmaceutical analytical chemistry, faculty of pharmacy, tanta university | Unknown | horus university | ||||
| 7 | 6 | the relationship of dietary omega-3 fatty acid and omega-6 to omega-3 ratio intake and likelihood of type 2 diabetes in a cross-sectional study. | there is a belief that consuming a significant amount of omega-3 and omega-6 fatty acids can positively affect chronic diseases. however, the connection between these fatty acids and type 2 diabetes mellitus (t2dm) risk remains unclear. to explore this further, we conducted a study to investigate the relationship between dietary intake of omega-3 and omega-6 fatty acids (fa), as well as omega-6 to omega-3 ratio, and the odds of t2dm. | bmc endocrine disorders | eng | 2024 | Nov | Shakiba Ebrahim, Pasdar Yahya, Asoudeh Farzaneh, Najafi Farid, Saber Amir, Shakiba Mohammad Hossein, Bagheri Amir | research center for environmental determinants of health (rcedh), health institute, kermanshah university of medical sciences, kermanshah, iran., research center for environmental determinants of health (rcedh), health institute, kermanshah university of medical sciences, kermanshah, iran., department of clinical nutrition, school of nutritional sciences and dietetics, tehran university of medical sciences, tehran, iran., research center for environmental determinants of health (rcedh), health institute, kermanshah university of medical sciences, kermanshah, iran., department of nutritional sciences, school of nutrition sciences and food technology, kermanshah university of medical sciences, kermanshah, iran., school of medicine, kermanshah university of medical sciences, kermanshah, iran., department of nutritional sciences, school of nutrition sciences and food technology, kermanshah university of medical sciences, kermanshah, iran. amir.baqerii@yahoo.com. | bmc endocrine disorders | bmc endocr disord | 1472-6823 | 2.8 | 3.1 | ENDOCRINOLOGY & METABOLISM|Q3|97/186 | health institute, kermanshah university of medical sciences, health institute, kermanshah university of medical sciences, tehran university of medical sciences, health institute, kermanshah university of medical sciences, kermanshah university of medical sciences, kermanshah university of medical sciences, kermanshah university of medical sciences | study | health institute | ||||
| 8 | 7 | association between alcohol consumption and risk of developing tuberculosis in patients with diabetes: a nationwide retrospective cohort study. | diabetes mellitus (dm) and alcohol consumption are risk factors for tuberculosis (tb). we investigated the association between alcohol consumption and tb development in individuals with type 2 dm (t2dm). | respiratory research | eng | 2024 | Nov | Chung Chiwook, Lee Kyu Na, Han Kyungdo, Park Junhee, Shin Dong Wook, Lee Sei Won | department of pulmonary and critical care medicine, gangneung asan hospital, university of ulsan college of medicine, gangneung, republic of korea., department of statistics and actuarial science, soongsil university, seoul, republic of korea., department of statistics and actuarial science, soongsil university, seoul, republic of korea., center for cohort studies, total healthcare center, kangbuk samsung hospital, sungkyunkwan university school of medicine, seoul, korea., department of family medicine, samsung medical center, sungkyunkwan university school of medicine, seoul, republic of korea. dwshin.md@gmail.com., department of pulmonary and critical care medicine, asan medical center, university of ulsan college of medicine, 88 olympic-ro 43-gil, songpa-gu, seoul, 05505, republic of korea. iseiwon@gmail.com. | respiratory research | resp res | 1465-993X | 4.7 | 5.3 | RESPIRATORY SYSTEM|Q1|17/100 | asan hospital, university of ulsan college of medicine, republic of korea, department of statistics and actuarial science, soongsil university, soongsil university, center for cohort studies, total healthcare center, kangbuk samsung hospital, sungkyunkwan university school of medicine, samsung medical center, sungkyunkwan university school of medicine, asan medical center, university of ulsan college of medicine | Unknown | ulsan college | ||||
| 9 | 8 | validation of two predictive models for survival in anaplastic thyroid cancer (atc). | the prognosis of patients with anaplastic thyroid cancer (atc) remains dismal. a small portion of patients experience longterm survival and need to be identified before treatment allocation. survival scores may guide clinicians making more informed decisions about treatment options and improve the understanding of patients' prognosis. the aim of this study was to validate two prognostic scores using an independent dataset to analyze which prognostic index is superior in discriminating survival. | bmc cancer | eng | 2024 | Nov | Käsmann Lukas, Nieto Alexander, Rennollet Robert, Gurtner Ralph, Oliinyk Dmytro, Augustin Teresa, Koehler Viktoria Florentine, Neu Maria, Belka Claus, Spitzweg Christine, Rauch Josefine | department of radiation oncology, university hospital, lmu munich, munich, 81377, germany. lukas.kaesmann@med.uni-muenchen.de., department of hematology and oncology, klinikum rechts der isar der tu münchen, ismaninger straße 22, munich, 81675, germany., department of radiation oncology, university hospital, lmu munich, munich, 81377, germany., department of radiation oncology, university hospital, lmu munich, munich, 81377, germany., department of plastic, hand and reconstructive surgery, university hospital regensburg, franz-josef-strauss-allee 11, regensburg, 93053, germany., department of radiation oncology, university hospital, lmu munich, munich, 81377, germany., department of medicine iv, lmu university hospital, lmu munich, munich, 81377, germany., department of radio-oncology, university hospital of augsburg, augsburg, germany., department of radiation oncology, university hospital, lmu munich, munich, 81377, germany., department of medicine iv, lmu university hospital, lmu munich, munich, 81377, germany., department of radiation oncology, university hospital, lmu munich, munich, 81377, germany. | bmc cancer | bmc cancer | 1471-2407 | 3.4 | 3.8 | ONCOLOGY|Q2|110/322 | department of radiation oncology, university hospital, lmu munich, klinikum rechts der isar der tu münchen, department of radiation oncology, university hospital, lmu munich, department of radiation oncology, university hospital, lmu munich, department of plastic, hand and reconstructive surgery, university hospital regensburg, department of radiation oncology, university hospital, lmu munich, department of medicine iv, lmu university hospital, lmu munich, university hospital of augsburg, department of radiation oncology, university hospital, lmu munich, department of medicine iv, lmu university hospital, lmu munich, department of radiation oncology, university hospital, lmu munich | Unknown | lmu university | ||||
| 10 | 9 | prevalence and association of sleep duration and different volumes of physical activity with type 2 diabetes: the first evidence from charls. | this study aimed to examine the prevalence of type 2 diabetes (t2d) and the independent and joint associations of sleep duration and different volumes of physical activity (pa) with t2d in the china health and retirement longitudinal study (charls). | bmc public health | eng | 2024 | Nov | Zhou Zigui, Tian Xuewen | school of exercise and health, shanghai university of sport, 200 hengren road, yangpu district, shanghai, 200438, china., school of exercise and health, shanghai university of sport, 200 hengren road, yangpu district, shanghai, 200438, china. xuewentian1978@163.com. | bmc public health | bmc public health | 1471-2458 | 3.5 | 3.9 | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH|Q1|84/403 | school of exercise and health, shanghai university of sport, school of exercise and health, shanghai university of sport | Unknown | shanghai university | shanghai university | 501–600 | 38.0 | |
| 11 | 10 | differences in maternal and perinatal outcomes between dutch and non-western women in a midwife-led care setting: a retrospective cohort study. | previous research has shown that genetics and maternal medical, sociodemographic, lifestyle and psychosocial factors affect maternal and perinatal outcomes. substantial research has been done on ethnic differences and maternal and perinatal outcomes in hospital settings. to our knowledge there are no studies about the associations between ethnicity and maternal and perinatal outcomes in a midwife-led care setting among low-risk women. therefore, our study aimed to investigate possible ethnic associations between non-western and dutch women, and maternal and perinatal outcomes in a midwife-led care setting. | bmc pregnancy and childbirth | eng | 2024 | Nov | Ali F, Horvat-Gitsels L A, Bakker P C A M, Verhoeven C J M, van der Wal J T Gitsels- | department of obstetrics and gynaecology, amsterdam umc location vrije universiteit amsterdam, de boelelaan 1117, amsterdam, the netherlands. f.ali1@amsterdamumc.nl., ucl great ormond street institute of child health, 30 guilford st, london, wc1n 1eh, uk., department of obstetrics and gynaecology, amsterdam umc location vrije universiteit amsterdam, de boelelaan 1117, amsterdam, the netherlands., midwifery science, amsterdam umc location vrije universiteit amsterdam, de boelelaan 1117, amsterdam, the netherlands., midwifery science, amsterdam umc location vrije universiteit amsterdam, de boelelaan 1117, amsterdam, the netherlands. | bmc pregnancy and childbirth | bmc pregnancy childb | 1471-2393 | 2.8 | 3.4 | OBSTETRICS & GYNECOLOGY|Q1|33/136 | department of obstetrics and gynaecology, vrije universiteit, ucl great ormond street institute of child health, department of obstetrics and gynaecology, vrije universiteit, midwifery science, vrije universiteit, midwifery science, vrije universiteit | substantial research | street institute | ||||
| 12 | 11 | major electrolyte disorder and associated factors among patients with chronic disease in ethiopia: a systematic review and meta-analysis. | alterations in electrolytes are associated with a number of clinical problems and prompt diagnosis of electrolyte disorder and treatment are crucial in the management of patients with chronic illness. even though, major electrolyte disorders are common among patients with chronic diseases, the problem were not received enough attention. thus, the aim of this review was to determine the pooled prevalence and associated factors of major electrolyte disorder among patients with chronic diseases. | bmc nephrology | eng | 2024 | Nov | Chekol Tassew Worku, Ferede Yeshiwas Ayale, Zeleke Agerie Mengistie | department of medical nursing, teda health science college, p.o. box 196, gondar, ethiopia. workukid16@gmail.com., department of reproductive health, teda health science college, gondar, ethiopia., department of clinical midwifery, teda health science college, gondar, ethiopia. | bmc nephrology | bmc nephrol | 1471-2369 | 2.2 | 2.6 | UROLOGY & NEPHROLOGY|Q2|54/126 | department of medical nursing, teda health science college, department of reproductive health, teda health science college, department of clinical midwifery, teda health science college | Unknown | science college | ||||
| 13 | 12 | association of insulin resistance with chronic kidney disease in individuals without diabetes in a community population in south china. | to explore the relationship of insulin resistance (ir) with chronic kidney disease (ckd) in individuals without diabetes. | bmc nephrology | eng | 2024 | Nov | Li Jiamin, Zhou Qin, Liu Zhen, Zou Hequn | department of nephrology, nanfang hospital baiyun branch of southern medical university, guangzhou, 510080, people's republic of china., department of nephrology, the central hospital of wuhan, wuhan, 430000, people's republic of china., department of nephrology, nanfang hospital baiyun branch of southern medical university, guangzhou, 510080, people's republic of china., school of medicine, the chinese university of hong kong, shenzhen, 518116, people's republic of china. zouhequn@cuhk.edu.cn. | bmc nephrology | bmc nephrol | 1471-2369 | 2.2 | 2.6 | UROLOGY & NEPHROLOGY|Q2|54/126 | nanfang hospital baiyun branch of southern medical university, people's republic of china, the central hospital of wuhan, people's republic of china, nanfang hospital baiyun branch of southern medical university, people's republic of china, the chinese university of hong kong, people's republic of china | Unknown | medical university | ||||
| 14 | 13 | the impact of pparγ and apoe gene polymorphisms on susceptibility to diabetic kidney disease in type 2 diabetes mellitus: a meta-analysis. | globally, diabetic kidney disease (dkd) has become the leading cause of end-stage renal disease, imposing substantial social and economic costs. this meta-analysis was designed to provide valuable insights into gene-disease interactions by investigating the potential association between lipid metabolism gene polymorphisms and the risk of dkd. | bmc nephrology | eng | 2024 | Nov | Taurbekova Binura, Mukhtarova Kymbat, Salpynov Zhandos, Atageldiyeva Kuralay, Sarria-Santamera Antonio | department of biomedical sciences, school of medicine, nazarbayev university, astana, kazakhstan. binura.taurbekova@nu.edu.kz., department of biomedical sciences, school of medicine, nazarbayev university, astana, kazakhstan., department of surgery, school of medicine, nazarbayev university, astana, kazakhstan., department of medicine, school of medicine, nazarbayev university, astana, kazakhstan., department of biomedical sciences, school of medicine, nazarbayev university, astana, kazakhstan. | bmc nephrology | bmc nephrol | 1471-2369 | 2.2 | 2.6 | UROLOGY & NEPHROLOGY|Q2|54/126 | school of medicine, nazarbayev university, school of medicine, nazarbayev university, school of medicine, nazarbayev university, school of medicine, nazarbayev university, school of medicine, nazarbayev university | meta-analysis | nazarbayev university | nazarbayev university | 501–600 | 29.5 | |
| 15 | 14 | investigation of the impact of exposure to trace elements on health and disease from the toxilaus study. | the toxilaus study aims at evaluating the impact of environmental toxic species on health and diseases' onset and development. specifically, the ubiquitous presence of trace elements (tes) in the environment urges for a better characterization of their influence on human organism. in its primary phase, the toxilaus study focused on measuring the urinary concentrations of 23 tes in the baseline samples from the colaus|psycolaus population-based cohort, using inductively coupled plasma mass spectrometry (icp-ms). statistical analyses were carried out on 5866 participants, investigating links between tes concentrations and smoking status, metabolic syndrome and body mass index (bmi). smoking status was associated with cd, zn, pb, mo and hg (respectively or = 3.64, 1.42, 1.20, 0.69 and 0.58) while metabolic syndrome was associated with zn and cd (or = 1.81 and 1.24 respectively). concentrations of zn, hg, co, ni, cu, mo, as, sn, tl, fe where significantly different (p < 0.0001) between bmi groups (normal, overweight, obese). finally, this study provides an overview of the distribution of trace elements in a cohort large sample of the general population, as well as their main associations with cardiovascular risk factors. theses relations will be further analysed in subsequent phases of the study. | scientific reports | eng | 2024 | Nov | Mouti Idriss, Perrais Maïwenn, Marques-Vidal Pedro, Thomas Aurélien, Vaucher Julien | department of medicine, internal medicine, lausanne university hospital and university of lausanne, rue du bugnon 46, 1011, lausanne, switzerland., unit of forensic chemistry and toxicology, university centre of legal medicine lausanne-geneva, geneva university hospital and university of geneva, rue michel-servet 1, 1211, geneva, switzerland., department of medicine, internal medicine, lausanne university hospital and university of lausanne, rue du bugnon 46, 1011, lausanne, switzerland., unit of forensic chemistry and toxicology, university centre of legal medicine lausanne-geneva, geneva university hospital and university of geneva, rue michel-servet 1, 1211, geneva, switzerland. aurelien.thomas@chuv.ch., department of medicine, internal medicine, lausanne university hospital and university of lausanne, rue du bugnon 46, 1011, lausanne, switzerland. julien.vaucher@h-fr.ch. | scientific reports | sci rep-uk | 2045-2322 | 2045-2322 | 3.8 | 4.3 | MULTIDISCIPLINARY SCIENCES|Q1|25/134 | department of medicine, lausanne university hospital, university of lausanne, unit of forensic chemistry and toxicology, university centre of legal medicine lausanne-geneva, geneva university hospital, university of geneva, department of medicine, lausanne university hospital, university of lausanne, unit of forensic chemistry and toxicology, university centre of legal medicine lausanne-geneva, geneva university hospital, university of geneva, department of medicine, lausanne university hospital, university of lausanne | toxilaus study | lausanne university | |||
| 16 | 15 | effects of nurse tele support via telephone calls on transition between specialized and primary care in type 2 diabetes mellitus patients: a consort-compliant randomized clinical trial. | the role of telemedicine in the transition to primary care for type 2 diabetes mellitus (t2dm) is yet unknown. we aimed to evaluate this issue in well-controlled t2dm patients discharged from a tertiary clinic. | endocrine | eng | 2024 | Nov | Moreira Ana Marina, Rados Dimitris Varvaki, de Farias Camila Bergonsi, Coelli Sabrina, de Almeida Faller Livia, Dos Santos Laura Ferraz, Matzenbacher Ana Maria, Katz Natan, Harzeim Erno, Silveiro Sandra Pinho | postgraduate program in medical sciences: endocrinology, universidade federal do rio grande do sul, porto alegre, brazil., postgraduate program in medical sciences: endocrinology, universidade federal do rio grande do sul, porto alegre, brazil., postgraduate program in medical sciences: endocrinology, universidade federal do rio grande do sul, porto alegre, brazil., postgraduate program in medical sciences: endocrinology, universidade federal do rio grande do sul, porto alegre, brazil., telessaúders project, federal university of rio grande do sul, porto alegre, brazil., telessaúders project, federal university of rio grande do sul, porto alegre, brazil., telessaúders project, federal university of rio grande do sul, porto alegre, brazil., telessaúders project, federal university of rio grande do sul, porto alegre, brazil., telessaúders project, federal university of rio grande do sul, porto alegre, brazil., postgraduate program in medical sciences: endocrinology, universidade federal do rio grande do sul, porto alegre, brazil. ssilveiro@hcpa.edu.br. | endocrine | endocrine | 1355-008X | 1559-0100 | 3.0 | 3.1 | ENDOCRINOLOGY & METABOLISM|Q2|88/186 | universidade federal do rio grande do sul, universidade federal do rio grande do sul, universidade federal do rio grande do sul, universidade federal do rio grande do sul, federal university of rio grande do sul, federal university of rio grande do sul, federal university of rio grande do sul, federal university of rio grande do sul, federal university of rio grande do sul, universidade federal do rio grande do sul | Unknown | federal university | |||
| 17 | 16 | association of comorbidity duration with the occurrence and prognosis of steatotic liver disease. | steatotic liver disease (sld) interacts with various comorbidities, impacting outcomes, yet little is known about the duration of comorbidities in sld occurrence and mortality. we investigated this relationship, focusing on disease predictors and mortality rates. | digestive diseases and sciences | eng | 2024 | Nov | Sang Hyunji, Lim Jihye, Kim Ha Il | department of endocrinology and metabolism, kyung hee university medical center, kyung hee university college of medicine, seoul, south korea., division of gastroenterology and hepatology, department of internal medicine, the catholic university college of medicine, seoul, south korea., department of gastroenterology and hepatology, hanyang university guri hospital, guri, south korea. harkim@hanyang.ac.kr. | digestive diseases and sciences | digest dis sci | 0163-2116 | 1573-2568 | 2.5 | 2.9 | GASTROENTEROLOGY & HEPATOLOGY|Q2|71/143 | kyung hee university medical center, kyung hee university college of medicine, the catholic university college of medicine, hanyang university guri hospital | Unknown | hee university | |||
| 18 | 17 | impact of haemoglobina1c on platelet reactivity and cardiovascular outcomes in patients undergoing drug-eluting stent implantation. | this study investigates the impact of hemoglobin a1c on platelet reactivity and cardiovascular outcomes in patients undergoing drug-eluting stent implantation. hba1c levels were categorized into 3 groups: < 6.5%, 6.5-8.5%, and > 8.5%. roc (resistance to clopidogrel) and roa (resistance to aspirin) were calculated. the primary endpoint was a composite of mace, including all-cause mortality, nonfatal mi, and ischemia-driven revascularization. the secondary endpoints comprised individual mace components. the incidence of roc was 9.3% (151 of 1621), whereas that of roa was 16.5% (268 of 1621). the roc for each of the 3 groups significantly increased with increasing hba1c levels [4.3% vs. 7.1% vs. 10.1%, p = 0.006]; however, the roa did not [16.4% vs. 17.7% vs. 14.3%, p = 0.694]. hba1c > 8.5 was significantly associated with roc (3.356 [1.231, 9.234], p = 0.009). compared with the hba1c < 6.5 subgroup, the hba1c˃8.5 subgroup was significantly associated with mace (3.142 [2.346, 4.206], < 0.001), nonfatal mi (2.297 [1.275, 4.137], p = 0.006) and ischemia-driven revascularization (3.845 [2.082, 7.101], p < 0.001), but not all-cause mortality (2.371 [0.551, 10.190], 0.246) at the 36-month follow-up. hba1c levels were positively correlated with roc, but the adverse cardiovascular events were driven by elevated hba1c, constituting an argument to intensify glycemic control in subjects with diabetes after intracoronary stent placement. | scientific reports | eng | 2024 | Nov | Wu Yilin, Jiang Xuan, Jiang Lijuan, Ji Hongyu, Liu Min, Li Weizhen | department of cardiology, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, 800 huangjiahuayuan road, shanghai, 201803, people's republic of china. wuyilin200311021@163.com., department of emergency and critical care, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, 800 huangjiahuayuan road, shanghai, 201803, people's republic of china., department of cardiology, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, 800 huangjiahuayuan road, shanghai, 201803, people's republic of china., department of cardiology, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, 800 huangjiahuayuan road, shanghai, 201803, people's republic of china., department of nursing, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, 800 huangjiahuayuan road, shanghai, 201803, people's republic of china. 381450955@qq.com., department of cardiology, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, 800 huangjiahuayuan road, shanghai, 201803, people's republic of china. weizhenlee@163.com. | scientific reports | sci rep-uk | 2045-2322 | 2045-2322 | 3.8 | 4.3 | MULTIDISCIPLINARY SCIENCES|Q1|25/134 | shanghai general hospital, shanghai jiaotong university school of medicine, people's republic of china, shanghai general hospital, shanghai jiaotong university school of medicine, people's republic of china, shanghai general hospital, shanghai jiaotong university school of medicine, people's republic of china, shanghai general hospital, shanghai jiaotong university school of medicine, people's republic of china, shanghai general hospital, shanghai jiaotong university school of medicine, people's republic of china, jiading branch of shanghai general hospital, shanghai jiaotong university school of medicine, people's republic of china | mace | jiaotong university | |||
| 19 | 18 | immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors. | immune checkpoint inhibitor (ici) therapies can increase the risk of cardiovascular events in survivors of cancer by worsening atherosclerosis. here we map the expression of immune checkpoints (ics) within human carotid and coronary atherosclerotic plaques, revealing a network of immune cell interactions that ici treatments can unintentionally target in arteries. we identify a population of mature, regulatory ccr7<sup>+</sup>fscn1<sup>+</sup> dendritic cells, similar to those described in tumors, as a hub of ic-mediated signaling within plaques. additionally, we show that type 2 diabetes and lipid-lowering therapies alter immune cell interactions through pd-1, ctla4, lag3 and other ic targets in clinical development, impacting plaque inflammation. this comprehensive map of the ic interactome in healthy and cardiometabolic disease states provides a framework for understanding the potential adverse and beneficial impacts of approved and investigational icis on atherosclerosis, setting the stage for designing ici strategies that minimize cardiovascular disease risk in cancer survivors. | nature cardiovascular research | eng | 2024 | Nov | Barcia Durán José Gabriel, Das Dayasagar, Gildea Michael, Amadori Letizia, Gourvest Morgane, Kaur Ravneet, Eberhardt Natalia, Smyrnis Panagiotis, Cilhoroz Burak, Sajja Swathy, Rahman Karishma, Fernandez Dawn M, Faries Peter, Narula Navneet, Vanguri Rami, Goldberg Ira J, Fisher Edward A, Berger Jeffrey S, Moore Kathryn J, Giannarelli Chiara | nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., division of cardiology, department of medicine, icahn school of medicine at mount sinai, new york, ny, usa., division of cardiology, department of medicine, icahn school of medicine at mount sinai, new york, ny, usa., department of surgery, vascular division, icahn school of medicine at mount sinai, new york, ny, usa., department of pathology, new york university grossman school of medicine, new york university langone health, new york, ny, usa., division of precision medicine, department of medicine, new york university grossman school of medicine, new york, ny, usa., division of endocrinology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa. kathryn.moore@nyulangone.org., nyu cardiovascular research center, division of cardiology, department of medicine, new york university grossman school of medicine, new york, ny, usa. chiara.giannarelli@nyulangone.org. | nature cardiovascular research | nat cardiovasc res | 2731-0590 | 9.4 | 9.4 | CARDIAC & CARDIOVASCULAR SYSTEMS|Q1|13/220 | nyu cardiovascular research center, department of medicine, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, department of medicine, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, department of medicine, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, nyu cardiovascular research center, division of cardiology, new york university, grossman school of medicine, division of cardiology, icahn school of medicine, division of cardiology, icahn school of medicine, icahn school of medicine, new york university, grossman school of medicine, new york university langone health | clinical development | york university | york university | 351–400 | 32.4 | |
| 20 | 19 | ezrin drives adaptation of monocytes to the inflamed lung microenvironment. | ezrin, an actin-binding protein, orchestrates the organization of the cortical cytoskeleton and plasma membrane during cell migration, adhesion, and proliferation. its role in monocytes/macrophages (mφs) is less understood. here, we used a monocyte/mφ-specific ezrin knock-out mouse model to investigate the contribution of ezrin to monocyte recruitment and adaptation to the lung extracellular matrix (ecm) in response to lipopolysaccharide (lps). our study revealed that lps induces ezrin expression in monocytes/mφs and is essential for monocytes to adhere to lung ecm, proliferate, and differentiate into tissue-resident interstitial mφs. mechanistically, the loss of ezrin in monocytes disrupts activation of focal adhesion kinase and akt serine-threonine protein kinase signaling, essential for lung-recruited monocytes and monocyte-derived mφs to adhere to the ecm, proliferate, and survive. in summary, our data show that ezrin plays a role beyond structural cellular support, influencing diverse monocytes/mφ processes and signaling pathways during inflammation, facilitating their differentiation into tissue-resident macrophages. | cell death & disease | eng | 2024 | Nov | Gudneppanavar Ravindra, Di Pietro Caterina, H Öz Hasan, Zhang Ping-Xia, Cheng Ee-Chun, Huang Pamela H, Tebaldi Toma, Biancon Giulia, Halene Stephanie, Hoppe Adam D, Kim Catherine, Gonzalez Anjelica L, Krause Diane S, Egan Marie E, Gupta Neetu, Murray Thomas S, Bruscia Emanuela M | department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., yale stem cell center, school of medicine, yale university, new haven, ct, usa., yale stem cell center, school of medicine, yale university, new haven, ct, usa., yale stem cell center, school of medicine, yale university, new haven, ct, usa., department of chemistry and biochemistry, south dakota state university, brookings, sd, usa., department of biomedical engineering, yale university, new haven, ct, usa., department of biomedical engineering, yale university, new haven, ct, usa., yale stem cell center, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of inflammation and immunity, cleveland clinic foundation, cleveland, oh, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa., department of pediatrics, school of medicine, yale university, new haven, ct, usa. emanuela.bruscia@yale.edu. | cell death & disease | cell death dis | 2041-4889 | 2041-4889 | 8.1 | 8.6 | CELL BIOLOGY|Q1|33/205 | school of medicine, yale university, school of medicine, yale university, school of medicine, yale university, school of medicine, yale university, school of medicine, yale university, school of medicine, yale university, yale stem cell center, school of medicine, yale university, yale stem cell center, school of medicine, yale university, yale stem cell center, school of medicine, yale university, south dakota state university, yale university, yale university, yale stem cell center, school of medicine, yale university, school of medicine, yale university, cleveland clinic foundation, school of medicine, yale university, school of medicine, yale university | Unknown | yale university | yale university | 10 | 94.9 |
| 21 | 20 | pretransplant diabetes mellitus and kidney transplant outcomes: a systematic review and meta-analysis. | studies have shown that kidney transplantation is affected by pretransplant comorbidities. however, their impacts on mortality and graft loss remain inconsistent. therefore, the purpose of our study was to collect data from multiple studies to analyze the impact of pretransplant diabetes mellitus on kidney transplant outcomes. | transplantation proceedings | eng | 2024 | Nov | Liu Chao, Chen Qian, Sun Zhou, Liang Guofu, Yan Fu, Niu Yulin | department of organ transplantation, affiliated hospital of guizhou medical university, guiyang, guizhou province, china; urinary surgery, the affiliated hospital of guizhou medical university, guiyang, guizhou province, china., department of organ transplantation, affiliated hospital of guizhou medical university, guiyang, guizhou province, china., department of organ transplantation, affiliated hospital of guizhou medical university, guiyang, guizhou province, china., department of organ transplantation, affiliated hospital of guizhou medical university, guiyang, guizhou province, china., department of organ transplantation, affiliated hospital of guizhou medical university, guiyang, guizhou province, china., department of organ transplantation, affiliated hospital of guizhou medical university, guiyang, guizhou province, china. electronic address: nddnyl@126.com. | transplantation proceedings | transpl p | 0041-1345 | 1873-2623 | 0.8 | 0.8 | TRANSPLANTATION|Q4|25/31 | department of organ transplantation, guizhou medical university, guizhou medical university, department of organ transplantation, guizhou medical university, department of organ transplantation, guizhou medical university, department of organ transplantation, guizhou medical university, department of organ transplantation, guizhou medical university, department of organ transplantation, guizhou medical university | studies | medical university | |||
| 22 | 21 | determining the quality of life and associated factors in patients with pressure injury. | this study aimed to determine the quality of life of patients with pressure injuries and the factors associated with them. | journal of tissue viability | eng | 2024 | Nov | Gül Şenay, Demir Ayşe Sılanur, Karadağ Ayişe, Karaçay Pelin | faculty of nursing, hacettepe university, ankara, turkiye. electronic address: senaygundogmus@gmail.com., school of nursing, koc university, i̇stanbul, turkiye., school of nursing, koc university, i̇stanbul, turkiye., school of nursing, koc university, i̇stanbul, turkiye. | journal of tissue viability | j tissue viability | 0965-206X | 1876-4746 | 2.4 | 2.9 | NURSING|Q1|35/191 | hacettepe university, koc university, school of nursing, koc university, school of nursing, koc university | Unknown | hacettepe university | hacettepe university | 601–800 | 26.8 |
| 23 | 22 | assessing causal relationships between diabetes mellitus and idiopathic pulmonary fibrosis: a mendelian randomisation study. | idiopathic pulmonary fibrosis (ipf) is a disease of progressive lung scarring. there is a known association between diabetes mellitus (dm) and ipf, but it is unclear whether a causal relationship exists between these traits. | thorax | eng | 2024 | Nov | Moss Samuel T, Minelli Cosetta, Leavy Olivia C, Allen Richard J, Oliver Nick, Wain Louise V, Jenkins Gisli, Stewart Iain | national heart and lung institute, imperial college london, london, uk stm33@leicester.ac.uk., national heart and lung institute, imperial college london, london, uk., department of population health sciences, university of leicester, leicester, uk., department of population health sciences, university of leicester, leicester, uk., department of metabolism, digestion and reproduction, imperial college london, london, uk., department of population health sciences, university of leicester, leicester, uk., national heart and lung institute, imperial college london, london, uk., national heart & lung institute, imperial college london, london, uk. | thorax | thorax | 0040-6376 | 1468-3296 | 9.0 | 8.4 | RESPIRATORY SYSTEM|Q1|7/100 | national heart and lung institute, imperial college london, national heart and lung institute, imperial college london, department of population health sciences, university of leicester, department of population health sciences, university of leicester, imperial college london, department of population health sciences, university of leicester, national heart and lung institute, imperial college london, national heart & lung institute, imperial college london | Unknown | lung institute | |||
| 24 | 23 | using artificial intelligence-informed experience-based co-design (ai-ebcd) to create a virtual reality-based mindfulness application to reduce diabetes distress: protocol for a mixed-methods feasibility study. | people with type 2 diabetes can experience diabetes distress which can negatively affect health outcomes. non-pharmacological interventions such as mindfulness can help address diabetes distress. however, face-to-face programmes can be constrained by cost, poor accessibility and lack of availability. mobile apps for mindfulness may overcome these issues but evidence of their effectiveness is limited, and some have poor interface design with basic visualisations and feedback. | bmj open | eng | 2024 | Nov | Ghosal Shraboni, Stanmore Emma, Sturt Jackie, Bogosian Angeliki, Woodcock David, Zhang Mengying, Milne Nicola, Mubita Womba, Robert Glenn, O'Connor Siobhan | school of health sciences, the university of manchester, manchester, uk., school of health sciences, the university of manchester, manchester, uk emma.stanmore@manchester.ac.uk., florence nightingale faculty of nursing, midwifery and palliative care, king's college london, london, uk., school of health sciences, city university of london, london, uk., patient and public involvement representative, king's college london, london, uk., school of health sciences, the university of manchester, manchester, uk., brooklands and northenden (wythenshawe) primary care network, manchester, uk., the christie nhs foundation trust, manchester, uk., florence nightingale faculty of nursing, midwifery and palliative care, king's college london, london, uk., florence nightingale faculty of nursing, midwifery and palliative care, king's college london, london, uk. | bmj open | bmj open | 2044-6055 | 2044-6055 | 2.4 | 2.7 | MEDICINE, GENERAL & INTERNAL|Q1|80/325 | the university of manchester, the university of manchester, king's college london, city university of london, king's college london, the university of manchester, the christie nhs foundation trust, king's college london, king's college london | Unknown | the university | |||
| 25 | 24 | factors influencing postoperative urinary retention after radical hysterectomy for cervical cancer: development and validation of a predictive model in a prospective cohort study in southwest china. | to explore influencing factors for postoperative urinary retention (pour) in cervical cancer patients and construct and validate a pour prediction model. | bmj open | eng | 2024 | Nov | Zuo Yan, Yang Kaixuan, Zhang Jianjun, Liu Xinru, Bai Zhilan, He Jingwen, Hu Xiaolin | west china school of nursing, sichuan university/department of gynecology and obstetrics nursing, west china second university hospital, sichuan university/key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, chengdu, sichuan, china., department of gynecology and obstetrics, west china second university hospital, sichuan university/key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, chengdu, sichuan, china., department of gynecology and obstetrics, west china second university hospital, sichuan university/key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, chengdu, sichuan, china., department of gynecology and obstetrics nursing, west china second university hospital, sichuan university/west china school of nursing, sichuan university/key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, chengdu, sichuan, china., department of gynecology and obstetrics nursing, west china second university hospital, sichuan university/west china school of nursing, sichuan university/key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, chengdu, sichuan, china., department of gynecology and obstetrics nursing, west china second university hospital, sichuan university/west china school of nursing, sichuan university/key laboratory of birth defects and related diseases of women and children (sichuan university), ministry of education, chengdu, sichuan, china., west china school of nursing, sichuan university/department of nursing, west china hospital, sichuan university, chengdu, sichuan, china huxiaolin1220@126.com. | bmj open | bmj open | 2044-6055 | 2044-6055 | 2.4 | 2.7 | MEDICINE, GENERAL & INTERNAL|Q1|80/325 | west china school of nursing, sichuan university, west china second university, sichuan university, sichuan university, ministry of education, west china second university, sichuan university, sichuan university, ministry of education, west china second university, sichuan university, sichuan university, ministry of education, west china second university, sichuan university, west china school of nursing, sichuan university, sichuan university, ministry of education, west china second university, sichuan university, west china school of nursing, sichuan university, sichuan university, ministry of education, west china second university, sichuan university, west china school of nursing, sichuan university, sichuan university, ministry of education, west china school of nursing, sichuan university, sichuan university | Unknown | china school | |||
| 26 | 25 | idiabetes platform-enhanced phenotyping of patients with diabetes for precision diagnosis, prognosis and treatment: study protocol for a cluster-randomised controlled study in tayside, scotland. | diabetes is a global health emergency with increasing prevalence and diabetes-associated morbidity and mortality. one of the challenges in optimising diabetes care is translating research advances in this heterogeneous disease into clinical care. a potential solution is the introduction of precision medicine approaches into diabetes care.we aim to develop a digital platform called 'intelligent diabetes' (idiabetes) to support a precision diabetes care model in scotland and assess its impact on the primary composite outcome of all-cause mortality, hospitalisation rate, renal function decline and glycaemic control. | bmj open | eng | 2024 | Nov | Lin YeunYi, Leith Damien, Abbott Michael, Barrett Rachael, Bell Samira, Croudace Tim J, Cunningham Scott, Dillon John, Donnan Peter, Farre Albert, Hernández Rodolfo, Lang Chim, McKenzie Stephanie, Mordi Ify, Morrow Susan, Munro Cameron, Philip Sam, Ryan Mandy, Wake Deborah, Wang Huan, Win Mya, Pearson Ewan | university of dundee, dundee, uk., university of dundee, dundee, uk., health economics research unit, university of aberdeen, aberdeen, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., dundee epidemiology and biostatistics unit, university of dundee, dundee, uk., university of dundee, dundee, uk., health economics research unit, university of aberdeen, aberdeen, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., edinburgh surgery online, university of edinburgh division of clinical and surgical sciences, edinburgh, edinburgh, uk., nhs tayside, dundee, uk., nhs education for scotland, aberdeen, uk., health economics research unit, university of aberdeen, aberdeen, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., university of dundee, dundee, uk., university of dundee, dundee, uk e.z.pearson@dundee.ac.uk., No Affiliation, No Affiliation | bmj open | bmj open | 2044-6055 | 2044-6055 | 2.4 | 2.7 | MEDICINE, GENERAL & INTERNAL|Q1|80/325 | university of dundee, university of dundee, university of aberdeen, university of dundee, university of dundee, university of dundee, university of dundee, university of dundee, university of dundee, university of dundee, university of aberdeen, university of dundee, university of dundee, university of dundee, university of edinburgh, nhs education for scotland, university of aberdeen, university of dundee, university of dundee, university of dundee, university of dundee | Unknown | unknown | |||
| 27 | 26 | investigating the effect of verapamil on preservation of beta-cell function in adults with newly diagnosed type 1 diabetes mellitus (ver-a-t1d): protocol for a randomised, double-blind, placebo-controlled, parallel-group, multicentre trial. | type 1 diabetes mellitus (t1dm) is a disorder that arises following the selective autoimmune destruction of the insulin-producing beta cells. beta-cell protective or beta-cell regenerative approaches have gained wider attention, and pharmacological approaches to protect the patient's own insulin-producing beta-cell mass have been proposed. verapamil is an l-type calcium channel blocker that has been reported to effectively lowers beta-cell thioredoxin-interacting protein expression in rodent beta cells and islets, as well as in human islets, and thus promotes functional beta-cell mass. | bmj open | eng | 2024 | Nov | Wych Julie, Brunner Martina, Stenson Rachel, Chmura Piotr Jaroslaw, Danne Thomas, Mander Adrian Paul, Mathieu Chantal, Dayan Colin, Pieber Thomas R | centre for trials research, cardiff university, cardiff, uk wychj@cardiff.ac.uk., department of internal medicine, division of endocrinology and diabetology, medical university of graz, graz, austria., diabetes research group, cardiff university, cardiff, uk., center for protein research, kobenhavns universitet sundhedsvidenskabelige fakultet, kobenhavn, denmark., department of general pediatrics endocrinology/diabetology & clinical research, auf der bult children's hospital, hannover, germany., centre for trials research, cardiff university, cardiff, uk., katholieke universiteit leuven, uz leuven, leuven, belgium., cardiff university school of medicine, cardiff university, cardiff, uk., department of internal medicine, division of endocrinology and diabetology, medical university of graz, graz, austria. | bmj open | bmj open | 2044-6055 | 2044-6055 | 2.4 | 2.7 | MEDICINE, GENERAL & INTERNAL|Q1|80/325 | cardiff university, division of endocrinology and diabetology, medical university of graz, cardiff university, kobenhavns universitet sundhedsvidenskabelige fakultet, cardiff university, katholieke universiteit leuven, cardiff university, cardiff university, division of endocrinology and diabetology, medical university of graz | Unknown | cardiff university | cardiff university | 190 | 39.6 |
| 28 | 27 | [cardiovascular preventive recommendations. papps 2024 thematic updates]. | the recommendations of the semfyc's program for preventive activities and health promotion (papps) for the prevention of vascular diseases (vd) are presented. new in this edition are new sections such as obesity, chronic kidney disease and metabolic hepatic steatosis, as well as a 'don't do' section in the different pathologies treated. the sections have been updated: epidemiological review, where the current morbidity and mortality of cvd in spain and its evolution as well as the main risk factors are described; vascular risk (vr) and recommendations for the calculation of cv risk; main risk factors such as arterial hypertension, dyslipidemia and diabetes mellitus, describing the method for their diagnosis, therapeutic objectives and recommendations for lifestyle measures and pharmacological treatment; indications for antiplatelet therapy, and recommendations for screening of atrial fibrillation, and recommendations for management of chronic conditions. the quality of testing and the strength of the recommendation are included in the main recommendations. | atencion primaria | spa | 2024 | Nov | Orozco-Beltrán Domingo, Brotons-Cuixart Carlos, Banegas José R, Gil-Guillen Vicente F, Cebrián-Cuenca Ana M, Martín-Rioboó Enrique, Jordá-Baldó Ariana, Vicuña Johanna, Navarro-Pérez Jorge | medicina familiar y comunitaria, unidad de investigación cs cabo huertas, departamento san juan de alicante. departamento de medicina clínica. centro de investigación en atención primaria. universidad miguel hernández, san juan de alicante, españa. electronic address: dorozco@umh.es., medicina familiar y comunitaria. institut de recerca sant pau (ir sant pau). equipo de atención primaria sardenya, barcelona, españa., medicina preventiva y salud pública, universidad autónoma de madrid y ciberesp, madrid, españa., medicina familiar y comunitaria. hospital universitario de elda. departamento de medicina clínica. centro de investigación en atención primaria. universidad miguel hernández, san juan de alicante, españa., medicina familiar y comunitaria, centro de salud cartagena casco antiguo, cartagena, murcia, españa. instituto de investigación biomédica de murcia (imib), universidad católica de murcia, murcia, españa., medicina familiar y comunitaria, centro de salud poniente, córdoba. departamento de medicina. universidad de córdoba. grupo papps, córdoba, españa., medicina familiar y comunitaria. centro de salud plasencia ii, plasencia, cáceres, españa., medicina preventiva y salud pública. hospital de la sant creu i sant pau, barcelona, españa., medicina familiar y comunitaria, centro de salud salvador pau (valencia). departamento de medicina. universidad de valencia. instituto de investigación incliva, valencia, españa. | atencion primaria | aten prim | 0212-6567 | 1578-1275 | 1.8 | 1.6 | PRIMARY HEALTH CARE|Q3|18/30 | universidad miguel hernández, institut de recerca sant pau (ir sant pau), universidad autónoma de madrid y ciberesp, hospital universitario de elda, universidad miguel hernández, instituto de investigación biomédica de murcia (imib), universidad católica de murcia, centro de salud poniente, universidad de córdoba, grupo papps, centro de salud plasencia ii, centro de salud salvador pau (valencia), universidad de valencia, instituto de investigación incliva | epidemiological review | unknown | |||
| 29 | 28 | association between adipose deposition and mortality among adults without major cardiovascular risk factors. | to examine the association between adiposity and mortality in u.s. adults without major cardiovascular risk factors. | diabetes & metabolism | eng | 2024 | Nov | Claudel Sophie E, Verma Ashish | department of medicine, boston medical center, boston, ma, usa., department of medicine, section of nephrology, boston university chobanian & avedisian school of medicine, boston, ma, usa. electronic address: ashverma@bu.edu. | diabetes & metabolism | diabetes metab | 1262-3636 | 1878-1780 | 4.6 | 5.1 | ENDOCRINOLOGY & METABOLISM|Q1|36/186 | department of medicine, boston medical center, department of medicine, boston university chobanian & avedisian school of medicine | Unknown | boston university | boston university | 78 | 54.1 |
| 30 | 29 | improved glycemic and weight control with dulaglutide addition in sglt2 inhibitor treated obese type 2 diabetic patients at high cardiovascular risk in a real-world setting. the aware -2 study. | we evaluated the effects on glycemic control and body weight of glp1-ra in obese type 2 diabetic patients treated with sglt2-inhibitors and other hypoglycemic agents and/or insulin, in a real-world setting. a cohort of 583 type 2 diabetic outpatients treated with an sglt2 inhibitor and/or other anti-diabetic medications were examined. because patients had suboptimal glycemic control, the glp1-r.a. dulaglutide was added to ongoing medications. at 6 months, 334 patients had a follow-up visit. patients were classified in terms of cardiovascular risk (cvr) employing the esc-easd 2019 criteria, with the aware app. the study's primary endpoints were changes in: 1) hba1c level, 2) bmi, and 3) body weight after six months of treatment. secondary endpoints were evaluation of dulaglutide addition in type 2 diabetic patients: 1) with more or less than ten years of t2dm; 2) more or less than 75 years of age and in different subgroups of cvr. in the 334 patients which had a 6 months follow-up visit, age was 65,9+9,8; 33.5% (112) were females and 66.5% (222) were males. after six months of dulaglutide treatment, we found a significant reduction in hba1c levels (8.0+10.5mmol/mol; p<0.0001) and in body mass index (1.1+1.1kg/m<sup>2</sup>; p<0.0001). efficacy of dulaglutide was not affected by different cvd risk categories, age and t2dm duration. this real world study provide evidence for significant reductions in hba1c level, body mass index, and body weight in obese type 2 diabetic patients who received add-on treatment with a weekly glp-1ra, dulaglutide. | pharmacological research | eng | 2024 | Nov | Berra Cesare, Manfrini Roberto, Bifari Francesco, Cipponeri Elisa, Ghelardi Renata, Centofanti Lucia, Mortola Umberto, Lunati Elena, Bucciarelli Loredana, Cimino Vincenzo, Folli Franco | department of endocrinology and metabolic diseases, irccs multimedica, milan, italy. electronic address: cesare.berra@multimedica.it., department of endocrinology and metabolic diseases, irccs multimedica, milan, italy; departmental unit of diabetes and metabolism, san paolo hospital, asst santi paolo e carlo, milan, italy; endocrinology and metabolism, department of health science, università degli studi di milano, milan, italy., laboratory of cell metabolism and regenerative medicine, department of medical biotechnology and translational medicine, university of milan, lita, segrate, italy., department of endocrinology and metabolic diseases, irccs multimedica, milan, italy; department of biomedical sciences for health, university of milan, milan, italy., uoc coordinamento e integrazione rete asst melegnano e della martesana., endocrinology and metabolism, department of health science, università degli studi di milano, milan, italy., endocrinology and metabolism, department of health science, università degli studi di milano, milan, italy., division of endocrinology, asst fatebenefratelli-sacco, milan, italy., international center for t1d, pediatric clinical research center romeo ed enrica invernizzi, dibic, università di milano, milan, italy., department of biomedical and clinical sciences l. sacco endocrinology and diabetology, milan, italy., departmental unit of diabetes and metabolism, san paolo hospital, asst santi paolo e carlo, milan, italy; endocrinology and metabolism, department of health science, università degli studi di milano, milan, italy. electronic address: franco.folli@unimi.it. | pharmacological research | pharmacol res | 1043-6618 | 1096-1186 | 9.1 | 9.0 | PHARMACOLOGY & PHARMACY|Q1|13/354 | irccs multimedica, irccs multimedica, san paolo hospital, università degli studi di milano, university of milan, irccs multimedica, university of milan, uoc coordinamento e integrazione rete asst melegnano e della martesana, università degli studi di milano, università degli studi di milano, international center for t1d, università di milano, san paolo hospital, università degli studi di milano | Unknown | unknown | |||
| 31 | 30 | high glucose enhances malignant progression of mda-mb-231 cells through cumulative effect. | previous investigations have shown that high glucose can promote breast cancer progression. however, the relationship between high glucose microenvironment and triple-negative breast cancer (tnbc) remains to be explored. in this study, we performed rna-seq to explore the effect of short-term high glucose and long-term high glucose on mda-mb-231 cell line. a total of 896 highly ranked differentially expressed genes (degs) were identified, including 57 degs of short-term high glucose group and 839 degs of long-term high glucose group. the degs of short-term high glucose group were mainly associated with il-17 signaling pathway. nonetheless, the degs of long-term high glucose group were primarily involved in il-17 signaling pathway, mapk signaling pathway, tnf signaling pathway, age-rage signaling pathway in diabetic complications, toll-like receptor signaling pathway, and vegf signaling pathway. additionally, 8 hub genes of short-term high glucose group were enriched in metabolic pathway. moreover, 10 hub genes of long-term high glucose group were enriched in ribosome pathway. subsequently, in vitro experiment results found that high glucose can promote cell proliferation, and has a time accumulation effect. in addition, high glucose can induce the accumulation of inflammatory factors and promote angiogenesis. collectively, these findings provide novel insights into the effect of diabetes mellitus type 2 (t2dm) on tnbc. | toxicology letters | eng | 2024 | Nov | Zhang Gaotao, Liu Zhiqin, Zheng Huixin, Xu Yuanzhuang, Zhang Donghao, Chen Queting, Luo Duqiang | college of life science, key laboratory of medicinal chemistry and molecular diagnosis of ministry of education, hebei university, baoding, 071002, china., key laboratory of pharmaceutical quality control of hebei province, college of pharmaceutical science, hebei university; state key laboratory of new pharmaceutical preparations and excipients, key laboratory of medicinal chemistry and molecular diagnosis of ministry of education, hebei university, baoding, 071002, china. electronic address: zhiqinliu999@126.com., college of life science, key laboratory of medicinal chemistry and molecular diagnosis of ministry of education, hebei university, baoding, 071002, china., college of life science, key laboratory of medicinal chemistry and molecular diagnosis of ministry of education, hebei university, baoding, 071002, china., college of life science, key laboratory of medicinal chemistry and molecular diagnosis of ministry of education, hebei university, baoding, 071002, china., affiliated hospital of hebei university, baoding, 071000, china. electronic address: quetingchen@126.com., college of life science, key laboratory of medicinal chemistry and molecular diagnosis of ministry of education, hebei university, baoding, 071002, china. electronic address: duqiangluo999@126.com. | toxicology letters | toxicol lett | 0378-4274 | 1879-3169 | 2.9 | 3.2 | TOXICOLOGY|Q2|49/106 | college of life science, ministry of education, hebei university, hebei university, ministry of education, hebei university, college of life science, ministry of education, hebei university, college of life science, ministry of education, hebei university, college of life science, ministry of education, hebei university, hebei university, college of life science, ministry of education, hebei university | rna-seq | hebei university | |||
| 32 | 31 | associations between subjective and objective well-being and risk of cardiometabolic disease: a prospective cohort study from the uk biobank. | the distinct and combined impacts of subjective well-being (swb) and objective well-being (owb) on cardiometabolic diseases and cardiometabolic multimorbidity remain largely unknown. | journal of affective disorders | eng | 2024 | Nov | Hou Yabing, Yang Hongxi, Fu Yinghong, Zhang Mengnan, Lu Zuolin | department of medical information technology and management, yanjing medical college, capital medical university, beijing, china. electronic address: houyabing@ccmu.edu.cn., department of bioinformatics, school of basic medical sciences, tianjin medical university, tianjin, china. electronic address: yanghongxi@tmu.edu.cn., department of medical information technology and management, yanjing medical college, capital medical university, beijing, china. electronic address: fuyinghong@ccmu.edu.cn., department of bioinformatics, school of basic medical sciences, tianjin medical university, tianjin, china. electronic address: zhangmengnan@tmu.edu.cn., school of population medical and public health, chinese academy of medical sciences & peking union medical college, beijing, china. electronic address: luzuolin@cams.cn. | journal of affective disorders | j affect disorders | 0165-0327 | 1573-2517 | 4.9 | 5.4 | PSYCHIATRY|Q1|38/276 | yanjing medical college, capital medical university, school of basic medical sciences, tianjin medical university, yanjing medical college, capital medical university, school of basic medical sciences, tianjin medical university, chinese academy of medical sciences, peking union medical college | Unknown | medical college | |||
| 33 | 32 | association of abo blood group with risk of coronary stent thrombosis. | abo blood group's influence on cardiovascular risk, particularly in venous thromboembolism and coronary artery disease (cad), is well-studied, with non-o blood groups associated with heightened cad risk. however, its impact on stent thrombosis remains an unexplored area, prompting the question of whether abo blood groups are also associated with risk of early stent thrombosis. | international journal of cardiology | eng | 2024 | Nov | Demirel Caglayan, Hamzaraj Kevin, Fangl Janina, Hemetsberger Rayyan, Krychtiuk Konstantin A, Roth Christian, Gangl Clemens, Bartko Philipp E, Hengstenberg Christian, Berger Rudolf, Lang Irene M, Speidl Walter S | department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine i, cardiology and nephrology, hospital of st. john of god, eisenstadt, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria., department of internal medicine ii, division of cardiology, medical university of vienna, vienna, austria; ludwig boltzmann institute for cardiovascular research, vienna, austria. electronic address: walter.speidl@meduniwien.ac.at. | international journal of cardiology | int j cardiol | 0167-5273 | 1874-1754 | 3.2 | 3.2 | CARDIAC & CARDIOVASCULAR SYSTEMS|Q2|62/220 | medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, hospital of st. john of god, division of cardiology, medical university of vienna, division of cardiology, medical university of vienna, ludwig boltzmann institute for cardiovascular research | Unknown | medical university | |||
| 34 | 33 | a preliminary assessment of barriers and facilitators to accessing footcare in homeless shelters: a scoping review. | by examining the scientific literature, this scoping review aims to explore the most common foot problems people experiencing homelessness (peh) experience, as well as to explore the potential strategies for addressing foot problems in peh, such as foot clinics, foot screening and foot care for adults experiencing homelessness. | annals of vascular surgery | eng | 2024 | Nov | Benadda Imen, Lozano-Franco Rebecca, Coutu Félix-Antoine, Wells Sarah, Ades Matthew, Nauche Bénédicte, Drudi Laura M | faculty of medicine and health sciences, mcgill university, montreal, qc., faculty of medicine and health sciences, mcgill university, montreal, qc., faculty of medicine and health sciences, mcgill university, montreal, qc., innovation hub, centre de recherche du centre hospitalier de montréal, montréal, qc., department of medicine, mcgill university, division of general internal medicine, montréal, qc., medical libraries, centre hospitalier de l'université de montréal, montréal, qc., innovation hub, centre de recherche du centre hospitalier de montréal, montréal, qc; division of vascular surgery, centre hospitalier de l'université de montréal montréal, qc. electronic address: laura.drudi.med@ssss.gouv.qc.ca. | annals of vascular surgery | ann vasc surg | 0890-5096 | 1615-5947 | 1.4 | 1.4 | SURGERY|Q3|165/290 | faculty of medicine and health sciences, mcgill university, faculty of medicine and health sciences, mcgill university, faculty of medicine and health sciences, mcgill university, mcgill university, centre hospitalier de l'université de montréal, centre hospitalier de l'université de montréal | scoping review | mcgill university | mcgill university | 49 | 72.3 |
| 35 | 34 | caragana jubata ethanol extract ameliorates the symptoms of stz-hfd-induced t2dm mice by pkc/glut4 pathway. | caragana jubata (pall.) poir., a traditional tibetan medicinal plant in china, is renowned in tibetan medicine for its hypoglycemic properties and long-standing use in treating diabetes. despite its extensive clinical use, the mechanisms underlying its blood sugar-lowering effects still need to be explored. our investigation contributes a new understanding of the hypoglycemic mechanism of c. jubata, validating its traditional medicinal application by demonstrating its ability to increase glut4 expression and glucose uptake, crucial elements in treating type 2 diabetes mellitus (t2dm). | journal of ethnopharmacology | eng | 2024 | Nov | Zhao Ping, Zhong Shunhua, Liao Jingya, Tao Jingze, Yao Yanhong, Song Ping, Yang Xinzhou | south-central minzu university, 182 min-zu road, wuhan 430074, china., south-central minzu university, 182 min-zu road, wuhan 430074, china., south-central minzu university, 182 min-zu road, wuhan 430074, china., south-central minzu university, 182 min-zu road, wuhan 430074, china., south-central minzu university, 182 min-zu road, wuhan 430074, china., college of chemistry and chemical engineering, qinghai nationalities university, xining 810007, china. electronic address: spzhe@126.com., south-central minzu university, 182 min-zu road, wuhan 430074, china. electronic address: xzyang@mail.scuec.edu.cn. | journal of ethnopharmacology | j ethnopharmacol | 0378-8741 | 1872-7573 | 4.8 | 4.8 | PLANT SCIENCES|Q1|31/265 | south-central minzu university, south-central minzu university, south-central minzu university, south-central minzu university, south-central minzu university, college of chemistry and chemical engineering, qinghai nationalities university, south-central minzu university | investigation | minzu university | |||
| 36 | 35 | elevated lipid accumulation product trajectory patterns are associated with increasing incident risk of type 2 diabetes mellitus in china. | our study aimed to identify the trajectory patterns of lipid accumulation product (lap) and investigate their association with the incident risk of type 2 diabetes mellitus (t2dm) in china. | preventive medicine | eng | 2024 | Nov | Wu Yuying, Zhang Yanyan, Zhao Yang, Zhang Xing, Gu Minqi, Huo Weifeng, Fu Xueru, Li Xi, Guo Botang, Li Jianxin, Lu Xiangfeng, Hu Fulan, Hu Dongsheng, Zhang Ming | department of biostatistics and epidemiology, school of public health, shenzhen university medical school, shenzhen, guangdong, pr china., department of epidemiology, center for global health, school of public health, nanjing medical university, nanjing, jiangsu, pr china., department of general practice, affiliated luohu hospital of shenzhen university medical school, shenzhen, guangdong, pr china., department of biostatistics and epidemiology, school of public health, shenzhen university medical school, shenzhen, guangdong, pr china., department of biostatistics and epidemiology, school of public health, shenzhen university medical school, shenzhen, guangdong, pr china., department of epidemiology and biostatistics, college of public health, zhengzhou university, zhengzhou, henan, pr china., department of epidemiology and biostatistics, college of public health, zhengzhou university, zhengzhou, henan, pr china., department of epidemiology and biostatistics, college of public health, zhengzhou university, zhengzhou, henan, pr china., department of general practice, affiliated luohu hospital of shenzhen university medical school, shenzhen, guangdong, pr china., key laboratory of cardiovascular epidemiology, chinese academy of medical sciences, department of epidemiology, fuwai hospital, national center for cardiovascular diseases, chinese academy of medical sciences and peking union medical college, beijing, pr china., key laboratory of cardiovascular epidemiology, chinese academy of medical sciences, department of epidemiology, fuwai hospital, national center for cardiovascular diseases, chinese academy of medical sciences and peking union medical college, beijing, pr china., department of biostatistics and epidemiology, school of public health, shenzhen university medical school, shenzhen, guangdong, pr china., department of biostatistics and epidemiology, school of public health, shenzhen university medical school, shenzhen, guangdong, pr china; department of general practice, affiliated luohu hospital of shenzhen university medical school, shenzhen, guangdong, pr china., department of biostatistics and epidemiology, school of public health, shenzhen university medical school, shenzhen, guangdong, pr china. electronic address: zhangming1720@sina.com. | preventive medicine | prev med | 0091-7435 | 1096-0260 | 4.3 | 4.2 | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH|Q1|47/403 | shenzhen university medical school, nanjing medical university, luohu hospital, shenzhen university medical school, shenzhen university medical school, shenzhen university medical school, zhengzhou university, zhengzhou university, zhengzhou university, luohu hospital, shenzhen university medical school, chinese academy of medical sciences, fuwai hospital, national center for cardiovascular diseases, chinese academy of medical sciences, peking union medical college, chinese academy of medical sciences, fuwai hospital, national center for cardiovascular diseases, chinese academy of medical sciences, peking union medical college, shenzhen university medical school, shenzhen university medical school, luohu hospital, shenzhen university medical school, shenzhen university medical school | Unknown | shenzhen university | shenzhen university | 351–400 | 34.3 |
| 37 | 36 | a single step transvaginal surgery in managing vesicovaginal fistula with grade iii cystocele in post hysterectomy patient: a case report and literature review. | vesicovaginal fistula (vvf) is a persistent issue, particularly after obstetric surgeries such as hysterectomy. complications like pelvic organ prolapse (pop) and underactive bladder often occur (barber and maher, 2013; rajaian et al., 2019). women with both vvf and cystocele experience reduced quality of life and psychological challenges (alio et al., 2011). this case report highlights the management of a woman with vvf and cystocele following hysterectomy. | international journal of surgery case reports | eng | 2024 | Nov | Rozidi Achmad Romy Syahrial, Djatisoesanto Wahjoe, Laksita Tetuka Bagus | department of urology, faculty of medicine, airlangga university, dr. soetomo general academic teaching hospital, surabaya, indonesia., department of urology, faculty of medicine, airlangga university, dr. soetomo general academic teaching hospital, surabaya, indonesia., department of urology, faculty of medicine, airlangga university, dr. soetomo general academic teaching hospital, surabaya, indonesia. electronic address: dr.tetuka@gmail.com. | international journal of surgery case reports | int j surg case rep | 2210-2612 | 2210-2612 | 0.6 | 0.7 | SURGERY|Q4|239/290 | department of urology, faculty of medicine, airlangga university, dr. soetomo general academic teaching hospital, department of urology, faculty of medicine, airlangga university, dr. soetomo general academic teaching hospital, department of urology, faculty of medicine, airlangga university, dr. soetomo general academic teaching hospital | Unknown | airlangga university | |||
| 38 | 37 | general practice sleep scale - the "gpss" - a proposed new tool for use in general practice for risk assessment of obstructive sleep apnoea. | this pilot study investigated a new simplified osa screening tool that could be used in primary care/gp settings - the "gpss" tool - "general practice sleep scale" and compared against common existing osa screening tools. | sleep medicine | eng | 2024 | Nov | Howarth Timothy, Hedger Joe, Chen Winnie, Garg Himanshu, Heraganahally Subash S | darwin respiratory and sleep health, darwin private hospital, darwin, northern territory, australia; department of technical physics, university of eastern finland, kuopio, finland., flinders university, college of medicine and public health, darwin, northern territory, australia., flinders university, college of medicine and public health, darwin, northern territory, australia; general practice, danila dilba, aboriginal health service, darwin, northern territory, australia; menzies school of health research, darwin, northern territory, australia., department of respiratory and sleep medicine, royal darwin hospital, darwin, northern territory, australia., darwin respiratory and sleep health, darwin private hospital, darwin, northern territory, australia; department of respiratory and sleep medicine, royal darwin hospital, darwin, northern territory, australia; school of medicine, charles darwin university, darwin, northern territory, australia. electronic address: subash.heraganahally@nt.gov.au. | sleep medicine | sleep med | 1389-9457 | 1878-5506 | 3.8 | 4.0 | CLINICAL NEUROLOGY|Q1|59/277 | darwin private hospital, university of eastern finland, flinders university, college of medicine and public health, flinders university, college of medicine and public health, aboriginal health service, menzies school of health research, royal darwin hospital, darwin private hospital, royal darwin hospital, charles darwin university | pilot study | flinders university | flinders university | 301–350 | 35.4 |
| 39 | 38 | circadian clock disruption impairs immune oscillation in chronic endogenous hypercortisolism: a multi-level analysis from a multicentre clinical trial. | glucocorticoids (gc) are potent entrainers of the circadian clock. however, their effects on biological rhythms in chronic human exposure have yet to be studied. endogenous hypercortisolism (cushing's syndrome, cs) is a rare condition in which circadian disruption is sustained by a tumorous source of gc excess, offering the unique opportunity to investigate gc's chronic effects in vivo. | ebiomedicine | eng | 2024 | Nov | Hasenmajer Valeria, Sbardella Emilia, Sciarra Francesca, Simeoli Chiara, Pivonello Claudia, Ceccato Filippo, Pofi Riccardo, Minnetti Marianna, Rizzo Flavio, Ferrari Davide, Bonaventura Ilaria, Barbagallo Federica, Giannetta Elisa, Alunni Fegatelli Danilo, Conia Simone, Navigli Roberto, Arnaldi Giorgio, Scaroni Carla, Pivonello Rosario, Gianfrilli Daniele, Venneri Mary Anna, Isidori Andrea M | department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy., dipartimento di medicina clinica e chirurgia, sezione di endocrinologia, diabetologia, andrologia e nutrizione, università federico ii di napoli, naples, italy., dipartimento di sanità pubblica, università federico ii di napoli, naples, italy., endocrinology, dep of medicine, dimed, university-hospital of padova, padua, italy; endocrine disease unit, university-hospital of padova, padova, italy., oxford centre for diabetes, endocrinology and metabolism, nihr oxford biomedical research centre, university of oxford, churchill hospital, oxford, uk., department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy., department of medicine and surgery, kore university of enna, 94100, enna, italy., department of experimental medicine, "sapienza" university of rome, italy., department of public health and infectious disease, "sapienza" university of rome, rome, italy., sapienza nlp, department of computer, control and management engineering, "sapienza" university of rome, rome, italy., sapienza nlp, department of computer, control and management engineering, "sapienza" university of rome, rome, italy., departement of promozione della salute, materno-infantile, medicina interna e specialistica di eccellenza "g. d'alessandro" (promise), palermo university, 90127, palermo, italy., endocrinology, dep of medicine, dimed, university-hospital of padova, padua, italy; endocrine disease unit, university-hospital of padova, padova, italy., dipartimento di medicina clinica e chirurgia, sezione di endocrinologia, diabetologia, andrologia e nutrizione, università federico ii di napoli, naples, italy., department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy., department of experimental medicine, "sapienza" university of rome, italy; centre for rare diseases (endo-ern accredited), policlinico umberto i, rome, italy. electronic address: andrea.isidori@uniroma1.it. | ebiomedicine | ebiomedicine | 2352-3964 | 2352-3964 | 9.7 | 9.2 | MEDICINE, RESEARCH & EXPERIMENTAL|Q1|12/189 | university of rome, university of rome, university of rome, università federico ii di napoli, università federico ii di napoli, dimed, university-hospital of padova, university-hospital of padova, university of oxford, churchill hospital, university of rome, university of rome, university of rome, university of rome, kore university of enna, university of rome, university of rome, university of rome, university of rome, palermo university, dimed, university-hospital of padova, university-hospital of padova | Unknown | kore university | |||
| 40 | 39 | bibliometric analysis and visualisation of association studies between diabetes and osteoporosis. | no abstract | asian journal of surgery | eng | 2024 | Nov | Liu Jia, Ran Chuan, Liu Xuyang, Guo Wei | department of orthopedic surgery, the fengdu general hospital of chongqing, chongqing, china., department of orthopedic surgery, the fengdu general hospital of chongqing, chongqing, china., college of pharmacy, changchun university of science and technology, changchun, china., department of endocrinology, three gorges university hospital of traditional chinese medicine & yichang hospital of traditional chinese medicine, yichang, china. electronic address: gw2860@126.com. | asian journal of surgery | asian j surg | 1015-9584 | 0219-3108 | 3.5 | 3.1 | SURGERY|Q1|31/290 | department of orthopedic surgery, fengdu general hospital of chongqing, department of orthopedic surgery, fengdu general hospital of chongqing, college of pharmacy, changchun university of science and technology, three gorges university hospital of traditional chinese medicine, yichang hospital of traditional chinese medicine | Unknown | changchun university | |||
| 41 | 40 | molecular mechanisms of ubiquitination in wound healing. | wound healing is a complex biological process involving multiple cellular and molecular mechanisms. ubiquitination, a crucial post-translational modification, plays a vital role in regulating various aspects of wound healing through protein modification and degradation. this review comprehensively examines the molecular mechanisms of ubiquitination in wound healing, focusing on its regulation of inflammatory responses, macrophage polarization, angiogenesis, and the activities of fibroblasts and keratinocytes. we discuss how ubiquitination modifies key signaling pathways, including tgf-β/smad3, nf-κb, and hif-α, which are essential for proper wound healing. understanding these mechanisms provides insights into potential therapeutic strategies for treating impaired wound healing, particularly in conditions such as diabetes. the review highlights recent advances in understanding ubiquitination's role in wound healing and discusses future research directions for developing targeted therapeutic approaches. | biochemical pharmacology | eng | 2024 | Nov | Zhang Qianbo, Gu Rifang, Dai Yuhe, Chen Jitao, Ye Penghui, Zhu Huan, He Wenping, Nie Xuqiang | college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: qianbozhang@zmu.edu.cn., college of pharmacy, zunyi medical university, zunyi 563006, pr china; school medical office, zunyi medical university, zunyi 563006, pr china. electronic address: rf1055@163.com., college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: yuhedai@zmu.edu.cn., college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: jitaochen@zmu.edu.cn., college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: penghuiye@zmu.edu.cn., college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: huanzhu@zmu.edu.cn., college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: wenpinghe22@163.com., college of pharmacy, zunyi medical university, zunyi 563006, pr china; key lab of the basic pharmacology of the ministry of education & joint international research laboratory of ethnomedicine of ministry of education, zunyi medical university, zunyi 563006, pr china. electronic address: niexuqiang@126.com. | biochemical pharmacology | biochem pharmacol | 0006-2952 | 1873-2968 | 5.3 | 5.2 | PHARMACOLOGY & PHARMACY|Q1|34/354 | zunyi medical university, ministry of education, ministry of education, zunyi medical university, zunyi medical university, zunyi medical university, zunyi medical university, ministry of education, ministry of education, zunyi medical university, zunyi medical university, ministry of education, ministry of education, zunyi medical university, zunyi medical university, ministry of education, ministry of education, zunyi medical university, zunyi medical university, ministry of education, ministry of education, zunyi medical university, zunyi medical university, ministry of education, ministry of education, zunyi medical university | review | medical university | |||
| 42 | 41 | expression and localization of adiponectin in myoepithelial cells in sublingual glands of normal and diabetic rats. | adiponectin is a hormone produced by adipocytes with anti-atherosclerotic and anti-diabetic properties. we previously discovered that adiponectin is specifically localized in the myoepithelial cells of rat sublingual glands. this study aims to investigate the localization of adiponectin and its receptors, adipor1 and adipor2, in adult rats, postnatally developing rats, and diabetic model rats. | journal of oral biosciences | eng | 2024 | Nov | Miyake Genki, Nagasaka Arata, Bando Yasuhiko, Sakiyama Koji, Iseki Shoichi, Sakashita Hideaki, Amano Osamu | division of histology, meikai university school of dentistry, sakado, saitama, japan; division of oral and maxillofacial surgery, meikai university school of dentistry, sakado, saitama, japan., division of histology, meikai university school of dentistry, sakado, saitama, japan., division of histology, meikai university school of dentistry, sakado, saitama, japan., division of oral and maxillofacial surgery, meikai university school of dentistry, sakado, saitama, japan., division of anatomy, meikai university school of dentistry, sakado, saitama, japan., division of oral and maxillofacial surgery, meikai university school of dentistry, sakado, saitama, japan; faculty of health sciences department of clinical engineering, komatsu university, komatsu, ishikawa, japan; department of oral and maxillofacial surgery, abiko seijinkai hospital, abiko, chiba, japan., division of histology, meikai university school of dentistry, sakado, saitama, japan. electronic address: oamano@dent.meikai.ac.jp. | journal of oral biosciences | j oral biosci | 1349-0079 | 1880-3865 | 2.6 | 2.6 | DENTISTRY, ORAL SURGERY & MEDICINE|Q1|39/157 | meikai university, meikai university, meikai university, meikai university, meikai university, meikai university, meikai university, komatsu university, abiko seijinkai hospital, meikai university | this study | meikai university | meikai university | Reporter | n/a |
| 43 | 42 | integrating metabolomics and network pharmacology to investigate da-chai-hu decoction prevents kidney injury in diabetic mice. | the current treatment for diabetic nephropathy (dn) is inadequate, and there is an urgent need for an effective and minimally adverse alternative therapy. da-chai-hu decoction (dchd) is a time-honored herbal remedy from chinese medicine, boasting a legacy spanning more than 1800 years. clinical observations suggest that it may provide therapeutic benefits for individuals with type 2 diabetes mellitus (t2dm). nonetheless, the specific advantages of dchd in relation to diabetic nephropathy (dn) and the mechanisms through which it operates are still not well understood. | journal of ethnopharmacology | eng | 2024 | Nov | Wang Xue, Zhong Zhu-Jun, Chen Peng-Fei, Deng Chao-Fan, Chen Xiao-Mei, Xin Gui-Zhong, Tang Dan | key laboratory of digital quality evaluation of chinese materia medica of state administration of tcm and engineering & technology research center for chinese materia medica quality of guangdong province, guangdong pharmaceutical university, guangzhou 510006, china., state key laboratory of natural medicines, department of chinese medicines analysis, school of traditional chinese pharmacy, china pharmaceutical university, nanjing 2100011, china., key laboratory of digital quality evaluation of chinese materia medica of state administration of tcm and engineering & technology research center for chinese materia medica quality of guangdong province, guangdong pharmaceutical university, guangzhou 510006, china., key laboratory of digital quality evaluation of chinese materia medica of state administration of tcm and engineering & technology research center for chinese materia medica quality of guangdong province, guangdong pharmaceutical university, guangzhou 510006, china., key laboratory of digital quality evaluation of chinese materia medica of state administration of tcm and engineering & technology research center for chinese materia medica quality of guangdong province, guangdong pharmaceutical university, guangzhou 510006, china., state key laboratory of natural medicines, department of chinese medicines analysis, school of traditional chinese pharmacy, china pharmaceutical university, nanjing 2100011, china. electronic address: xinguizhong11184@126.com., key laboratory of digital quality evaluation of chinese materia medica of state administration of tcm and engineering & technology research center for chinese materia medica quality of guangdong province, guangdong pharmaceutical university, guangzhou 510006, china. electronic address: tdpharm@126.com. | journal of ethnopharmacology | j ethnopharmacol | 0378-8741 | 1872-7573 | 4.8 | 4.8 | PLANT SCIENCES|Q1|31/265 | state administration of tcm, guangdong pharmaceutical university, school of traditional chinese pharmacy, china pharmaceutical university, state administration of tcm, engineering & technology research center, guangdong pharmaceutical university, state administration of tcm, guangdong pharmaceutical university, state administration of tcm, guangdong pharmaceutical university, school of traditional chinese pharmacy, china pharmaceutical university, state administration of tcm, guangdong pharmaceutical university | Unknown | pharmaceutical university | |||
| 44 | 43 | specific loss of gipr signaling in gabaergic neurons enhances glp-1r agonist-induced body weight loss. | dual incretin agonists are among the most effective pharmaceutical treatments for obesity and type 2 diabetes to date. such therapeutics can target two receptors, such as the glucagon-like peptide-1 (glp-1) receptor and the glucose-dependent insulinotropic polypeptide (gip) receptor in the case of tirzepatide, to improve glycemia and reduce body weight. regarding body weight effects, gipr signaling is thought to involve at least two relevant mechanisms: the enhancement of food intake reduction and the attenuation of aversive effects caused by glp-1r agonists. although it is known that dual glp-1r-gipr agonism produces greater weight loss than glp-1r agonism alone, the precise mechanism is unknown. | molecular metabolism | eng | 2024 | Nov | Wean Jordan, Kowalsky Allison Ho, Laker Rhianna, Will Sarah, Drucker Daniel J, Rhodes Christopher J, Seeley Randy J | department of surgery, university of michigan, ann arbor, mi, usa., department of surgery, university of michigan, ann arbor, mi, usa., research and early development, cardiovascular, renal and metabolic diseases, biopharmaceuticals r&d, astrazeneca, gaithersburg, md, usa., research and early development, cardiovascular, renal and metabolic diseases, biopharmaceuticals r&d, astrazeneca, gaithersburg, md, usa., lunenfeld tanenbaum research institute, mount sinai hospital, department of medicine, university of toronto, toronto, canada., research and early development, cardiovascular, renal and metabolic diseases, biopharmaceuticals r&d, astrazeneca, gaithersburg, md, usa., department of surgery, university of michigan, ann arbor, mi, usa. electronic address: seeleyrj@med.umich.edu. | molecular metabolism | mol metab | 2212-8778 | 2212-8778 | 7.0 | 7.9 | ENDOCRINOLOGY & METABOLISM|Q1|16/186 | university of michigan, university of michigan, biopharmaceuticals r&d, lunenfeld tanenbaum research institute, mount sinai hospital, university of toronto, university of michigan | Unknown | research institute | |||
| 45 | 44 | il-1β-induced pericyte dysfunction with a secretory phenotype exacerbates retinal microenvironment inflammation via hes1/stat3 signaling pathway. | retinal pericytes are mural cells surrounding capillaries to maintain the integrity of blood-retina barrier and regulate vascular behaviors. pericyte loss has been considered as the hallmark of diabetic retinopathy (dr), which is a major complication of diabetes and the leading cause of blindness in adults. however, the precise function of pericytes in regulating the retinal microenvironment and the underlying mechanism remains largely unknown. in this study, we observed a secretory phenotype of pericytes with elevated inflammatory cytokines in response to interleukin-1β (il-1β), a canonical inflammatory cytokine which significantly increases during the initial stages of diabetic retinopathy. this phenotype is also accompanied by reduced expression of adherent junction proteins and contractile proteins. paracrine cytokines derived from pericytes further induce the chemotaxis of microglia cells and trigger detrimental changes in endothelial cells, including reduced expression of tight junction protein occludin and increased apoptosis. mechanically, the secretion potential in pericytes is partially mediated by hes1/stat3 signaling pathway. moreover, co-injection of stattic, an inhibitor targeting stat3 activation, could effectively attenuate il-1β-induced retinal inflammation and microglial activation in retina tissues. collectively, these findings demonstrate the potential of retinal pericytes as an initial inflammatory sensor prior to their anatomical pathological loss, via undergoing phenotypic changes and secreting paracrine factors to amplify local inflammation and damage endothelial cells in vitro. furthermore, inhibition of stat3 activation by inhibitors significantly ameliorates il-1β-induced retinal inflammation, suggesting stat3 in retinal pericytes as a promising target for alleviating dr and other il-1β-induced ocular diseases. | international immunopharmacology | eng | 2024 | Nov | Huang Caoxin, Zhang Xiaofang, Wu Menghua, Yang Chen, Ge Xilin, Chen Wenting, Li Xuejun, Liu Suhuan, Yang Shuyu | xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china. electronic address: cxhuang@xmu.edu.cn., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china; research center for translational medicine, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china. electronic address: liusuhuan@xmu.edu.cn., xiamen diabetes institute, fujian province key laboratory of translational research for diabetes, department of endocrinology and diabetes, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china; research studio of traditional chinese medicine, the first affiliated hospital of xiamen university, school of medicine, xiamen university, xiamen, fujian, china. electronic address: shuyuyang@xmu.edu.cn. | international immunopharmacology | int immunopharmacol | 1567-5769 | 1878-1705 | 4.8 | 5.0 | PHARMACOLOGY & PHARMACY|Q1|50/354 | xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen diabetes institute, department of endocrinology and diabetes, xiamen university, school of medicine, xiamen university, xiamen university, school of medicine, xiamen university | Unknown | diabetes institute | |||
| 46 | 45 | corrigendum to "mesenchymal stromal cells loaded with paclitaxel (paclimes) a potential new therapeutic approach on mesothelioma" [biochem. pharmacol. 214 (2023) 115678]. | no abstract | biochemical pharmacology | eng | 2024 | Nov | Coccè Valentina, Bonelli Mara, Monica Silvia La, Alfieri Roberta, Doneda Luisa, Martegani Eleonora, Alessandri Giulio, Lagrasta Costanza Annamaria, Giannì Aldo, Sordi Valeria, Petrella Francesco, Roncoroni Leda, Paino Francesca, Pessina Augusto | crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy., department of medicine and surgery, university of parma, 43126 parma, italy., department of medicine and surgery, university of parma, 43126 parma, italy., department of medicine and surgery, university of parma, 43126 parma, italy. electronic address: roberta.alfieri@unipr.it., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy., department of medicine and surgery, university of parma, 43126 parma, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy; maxillo-facial and dental unit, fondazione ca' granda irccs ospedale maggiore policlinico, 20122 milan, italy., diabetes research institute, irccs san raffaele hospital, 20132 milan, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy; department of thoracic surgery, irccs european institute of oncology, 20139 milan, italy; department of oncology and hemato-oncology, university of milan, 20122 milan, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy; center for prevention and diagnosis of celiac disease, gastroenterology and endoscopy unit. fondazione irccs ca' granda ospedale maggiore policlinico, 20122 milan, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy., crc stametec, department of biomedical, surgical and dental sciences, university of milan, 20122 milan, italy. | biochemical pharmacology | biochem pharmacol | 0006-2952 | 1873-2968 | 5.3 | 5.2 | PHARMACOLOGY & PHARMACY|Q1|34/354 | university of milan, university of parma, university of parma, university of parma, university of milan, university of milan, university of milan, university of parma, university of milan, fondazione ca' granda irccs ospedale maggiore policlinico, irccs san raffaele hospital, university of milan, irccs, university of milan, university of milan, university of milan, university of milan | Unknown | unknown | |||
| 47 | 46 | development and performance evaluation of a clinical prediction model for sepsis risk in burn patients. | sepsis is a common and severe complication in burn patients and remains one of the leading causes of mortality. this retrospective study aimed to develop a predictive model for the risk of in-hospital sepsis among burn patients treated at guangzhou red cross hospital between january 2022 and january 2024, with the goal of improving clinical outcomes through early prevention based on risk stratification. a total of 302 eligible patients were randomly divided into training and validation cohorts in a 7:3 ratio for model development and validation, respectively. predictive factors were initially selected using lasso regression, followed by logistic regression analysis to establish the prediction model and construct a nomogram. the final model incorporated 4 independent predictors: burn area (odds ratio [or] = 1.043, 95% confidence interval [ci]: 1.026-1.062/1%), hemoglobin (or = 0.968, 95% ci: 0.954-0.980/1 g/l), diabetes (or = 10.91, 95% ci: 2.563-56.62), and potassium (or = 3.091, 95% ci: 1.635-6.064/1 mmol/l). the areas under the receiver operating characteristic curve were 0.875 and 0.861 for the training and validation cohorts, with youden indexes of 0.634 and 0.600, respectively. the calibration curve and decision curve analysis demonstrated good predictive accuracy and clinical utility of the model. these findings suggest that our developed model exhibits robust predictive performance for the risk of in-hospital sepsis in burn patients, and early prevention strategies based on risk stratification may potentially improve clinical outcomes. | medicine | eng | 2024 | Nov | Luo Weiqing, Xiong Lei, Wang Jianshuo, Li Chen, Zhang Shaoheng | guangzhou red cross hospital of jinan university, guangzhou, china., No Affiliation, No Affiliation, No Affiliation, No Affiliation | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | guangzhou red cross hospital, jinan university, No Affiliation, No Affiliation, No Affiliation, No Affiliation | training and validation cohorts | jinan university | |||
| 48 | 47 | association between serum uric acid and prediabetes in a normal chinese population: a cross-sectional study. | cardiovascular events are frequent among individuals with prediabetes. and the relationship between cardiovascular diseases and elevated serum uric acid (sua) levels has been supported by extensive scientific evidence. however, there remains controversy regarding the correlation between elevated sua and prediabetes. the aim of this study was to investigate the association between elevated sua levels and the prevalence of prediabetes and gender differences in the association. a total of 190,891 individuals who participated in health checkups at the health promotion center of sir run run shaw hospital of zhejiang university from january 2017 to december 2021 were included in this cross-sectional study. the health checkups were carried out by trained general practitioners and nurses. the diagnostic criteria for diabetes and prediabetes are defined in the standards of medical care in diabetes-2022. the association between sua levels and diabetes and prediabetes was examined based on logistic regression analysis. the dose-response effect between sua levels and diabetes and prediabetes in both sexes was assessed using a restricted cubic spline (rcs) regression model. among 190,891 participants, this study included 106,482 males (55.8%) and 84,409 females (44.2%). there were 46,240 (24.2%) patients with prediabetes and 20,792 (10.9%) patients with diabetes. sua was divided into quartiles (q). compared to the sua q1 group, the prevalence of prediabetes was elevated in the sua q4 group (or = 1.378, 95% ci = 1.321-1.437), but diabetes risk was decreased in the sua q4 group (or = 0.690, 95% ci = 0.651-0.730). we found that sua levels were correlated with prediabetes more significantly in male subjects (or = 1.328, 95% ci = 1.272-1.386) than in female subjects (or = 1.184, 95% ci = 1.122-1.249) (p for interaction < .001). higher sua levels were strongly related to an elevated prevalence of prediabetes but a decreased prevalence of diabetes. the association of sua in prediabetes was more significant in men. | medicine | eng | 2024 | Nov | Shen Keqing, Huang Yilin, Zhang Junlu, Chen Liangli, Cai Xixuan, Pan Jianjiang, Li Jingyi, Li Lusha, Chen Liying | department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of pathology, second affiliated hospital of wenzhou medical university, wenzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china., department of general practice, sir run run shaw hospital, school of medicine, zhejiang university, hangzhou, zhejiang, china. | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | school of medicine, zhejiang university, school of medicine, zhejiang university, school of medicine, zhejiang university, wenzhou medical university, school of medicine, zhejiang university, school of medicine, zhejiang university, school of medicine, zhejiang university, school of medicine, zhejiang university, school of medicine, zhejiang university | cross-sectional study | zhejiang university | zhejiang university | 55 | 75.3 |
| 49 | 48 | comprehensive analysis of rheumatic diseases, comorbidities, and mortality in geriatric population: real-world data of 515 patients in a single rheumatology clinic. | rheumatic diseases present unique challenges in the elderly, with changes in the immune system contributing to varied clinical presentations. more individuals are now living with chronic diseases due to greater life expectancy, but there is a lack of real-world data about rheumatic diseases and comorbidities in older people. this study aimed to investigate disease types, comorbidities, treatments, and mortality in geriatric patients in comparison to non-geriatric patients at a rheumatology clinic. this retrospective observational cohort study reviewed the medical records of 2610 patients from january 2021 to january 2024 at 2 branches of a private hospital's rheumatology clinics. demographic information and data on rheumatic diseases, noninflammatory conditions, treatments, comorbidities, and mortality were collected, and geriatric patients were compared to non-geriatric patients. geriatric patients (n = 515) had a significantly higher prevalence of rheumatoid arthritis (50.6% vs 28.8%, p < .001), polymyalgia rheumatica (11.1% vs 0.2%, p < .001), and crystal arthritis (19.6% vs 8.8%, p < .001), with more frequent geriatric-onset cases. osteoarthritis was also more prevalent in geriatric patients (51.2% vs 11.3%, p < .001), while fibromyalgia was more common in the non-geriatric group (15.9% vs 4.1%, p < .001). geriatric patients experienced higher rates of comorbidities, including hypertension (72.4% vs 17.8%, p < .001), diabetes (33.6% vs 12.1%, p < .001), and osteoporosis (64.9% vs 35.4%, p < .001). these patients used more corticosteroids (74.5% vs 44%, p < .001), and conventional synthetic disease-modifying antirheumatic drugs (62.4% vs 49.4%, p < .001) but fewer biological disease-modifying antirheumatic drugs (9.2% vs 23.1%, p < .001). mortality rates were significantly higher in geriatric patients (6% vs 0.3%), with cancer (p = .001), ischemic heart disease (p = .04), heart failure (p = .01), chronic kidney disease (p = .02), and interstitial lung disease (p = .01) being associated with increased mortality. geriatric rheumatology should receive greater focus in future research to help address the anticipated increases in demand and to develop tailored management strategies for elderly patients with rheumatic diseases and comorbidities. | medicine | eng | 2024 | Nov | Tekeoglu Senem | department of medicine, rheumatology, school of medicine, halic university, istanbul, turkey. | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | department of medicine, rheumatology, school of medicine, halic university | retrospective observational cohort study | halic university | |||
| 50 | 49 | ruptured middle cerebral artery bifurcation aneurysms with concomitant intracerebral hematoma: clinical and morphological risk factors. | the prognosis for intracerebral hematoma (ich) following the rupture of a middle cerebral artery bifurcation (mbif) aneurysm is poor. we compared patients with isolated diffuse subarachnoid hemorrhage (sah) (without ich) following mbif aneurysm rupture to those with both sah and ich to evaluate clinical and morphological risk factors for ich. a retrospective study was conducted on 112 patients with ruptured mbif aneurysms treated between july 2016 and december 2021. we investigated age, sex, medical history (hypertension, diabetes mellitus, and smoking), rebleeding, aneurysm neck and dome size, bottleneck factor, aspect ratio, dome projection, trunk diameters and ratios, parent artery (m1) dimensions, angles between both trunks (γ1, γ2, γ3), as well as m1 length and diameter, and internal carotid artery/m1 (α) and internal carotid artery/anterior cerebral artery (β) angles. these measurements were obtained using computerized tomography angiography to assess risk factors. a total of 88 patients (78.6%) with ruptured mbif aneurysms who met the inclusion criteria were included in the study. a total of 39 (44.3%) patients had sah with ich, while 49 (53.7%) patients had pure diffuse sah. rebleeding was significantly higher in patients with ich (p = .02). morphological analysis revealed that the decrease in m1 diameter and α angle, along with an increase in aneurysm size and neck, were significantly different in the ich group (p = .025, p = .012, p = .009, and p = .005, respectively). receiver operating characteristic curve analysis showed that a cutoff value of α = 125° had the highest diagnostic accuracy (area under the curve = 0.71), with a sensitivity of 86.26% and specificity of 68.7%. the formation of ich following the rupture of mbif aneurysms is associated with specific morphological parameters. | medicine | eng | 2024 | Nov | Akdağ Rifat, Soylu Uğur | department of neurosurgery, yüksek i̇htisas training and research hospital, bursa, turkey., No Affiliation | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | department of neurosurgery, yüksek i̇htisas training and research hospital, No Affiliation | retrospective study | unknown | |||
| 51 | 50 | exploring the link between sirt1 gene variants and depression comorbidity in type 2 diabetes. | this study aims to (1) analyze the clinical characteristics and risk factors of patients with type 2 diabetes and comorbid depression and (2) explore the association between sirt1 gene single-nucleotide polymorphism sites and this comorbidity. a total of 450 type 2 diabetes patients hospitalized in the general medicine department at the central hospital of wuhan, tongji medical college, huazhong university of science and technology from july 2022 to september 2023, and 300 healthy individuals from the physical examination department were selected as study subjects. both groups were assessed using general information surveys and questionnaires. statistical analyses were performed to compare clinical indicators across 3 groups: individuals with only type 2 diabetes, those with comorbid depression, and healthy controls. the age, gender, disease duration, marital status, income and drug expenditure, employment status, fasting blood glucose level, fasting insulin level difference, insulin resistance index difference, glycated hemoglobin, high-density lipoprotein level, and hcy difference among the 3 groups of patients were risk factors for type 2 diabetes comorbid depression patients. the sirt1 mrna level was significantly reduced in type 2 diabetes comorbid depression patients. the sirt1 gene had 3 sites: rs12415800, rs3758391, and rs932658, which were related to the patient's type 2 diabetes comorbid depression. they were the additive model and dominant model of rs12415800 and rs3758391, respectively. in addition, the gtggt haplotype composed of rs12415800-rs932658-rs7895833-rs2273773-rs1467568 and the agact haplotype composed of rs3758391-rs932658-rs33957861-rs3818292-rs1467568 were significantly associated with type 2 diabetes comorbid depression. numerous factors influence the presence of depression in patients with type 2 diabetes, with the sirt1 gene playing a significant role, serving as a potential biomarker for this comorbidity. | medicine | eng | 2024 | Nov | He Yingxia, Wu Qinqin, Yin Ziwei, Zeng Yi, Xia Ningyu, Zhu Hong | department of general medicine, the central hospital of wuhan, tongji medical college, huazhong university of science and technology, wuhan, hubei, china., No Affiliation, No Affiliation, No Affiliation, No Affiliation, No Affiliation | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | the central hospital of wuhan, tongji medical college, huazhong university of science and technology, No Affiliation, No Affiliation, No Affiliation, No Affiliation, No Affiliation | Unknown | medical college | |||
| 52 | 51 | effects of genetic variants of organic cation transporters on metformin response in newly diagnosed patients with type 2 diabetes. | type 2 diabetes mellitus (t2dm) is a chronic disease that affects millions of people worldwide. metformin is the optimal initial therapy for patients with t2dm. genetic factors play a vital role in metformin response, including variations in drug efficacy and potential side effects. to determine the effects of genetic variants of multidrug and toxin extrusion protein 2 (mate2), ataxia telangiectasia mutated (atm), and serine/threonine kinase 11 (stk11) genes on metformin response in a cohort of saudi patients. this prospective observational study included 76 t2dm newly diagnosed saudi patients treated with metformin monotherapy and 80 control individuals. demographic data, lipid profiles, creatinine levels, and hemoglobin a1c (hba1c) levels were collected before and after treatment. all participants were genotyped for 5 single-nucleotide polymorphisms (snps), including rs4621031, rs34399035, rs2301759, rs1800058, and rs11212617, using taqman r genotyping assays. this study included 156 subjects. the subjects' mean ± sd age was 50.4 ± 10.14 years. the difference in hba1c levels in t2dm after treatment ranged from -1.20% to 8.8%, with a mean value of 0.927 ± 1.73%. in general, 73.7% of the patients with t2dm showed an adequate response to metformin (hba1c < 7%). stk11 (rs2301759) significantly affects the response to metformin in t2dm patients. in the rs2301759 single-nucleotide polymorphisms, the prevalence of an adequate response to metformin was significantly higher among patients with c/c and t/c genotypes than among non-responders (p = .021). however, no statistically significant associations were observed for the other tested snps. our study provides evidence of an association between stk11 (rs2301759) and response to metformin in saudi patients with t2dm. the need for targeted studies on specific gene-drug associations is emphasized, and further studies with a larger population should be conducted. | medicine | eng | 2024 | Nov | AlKreathy Huda M, Alzahrani Abdulhhakim A, Esmat Ahmed, Damanhouri Zoheir A | department of clinical pharmacology, faculty of medicine, king abdulaziz university, jeddah, saudi arabia., department of clinical pharmacology, faculty of medicine, king abdulaziz university, jeddah, saudi arabia., department of clinical pharmacology, faculty of medicine, king abdulaziz university, jeddah, saudi arabia., department of clinical pharmacology, faculty of medicine, king abdulaziz university, jeddah, saudi arabia. | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | faculty of medicine, king abdulaziz university, faculty of medicine, king abdulaziz university, faculty of medicine, king abdulaziz university, faculty of medicine, king abdulaziz university | prospective observational study | abdulaziz university | |||
| 53 | 52 | a comprehensive review of biomarker research in diabetic nephropathy from a global bibliometric and visualization perspective. | diabetic nephropathy (dn) is a common complication of diabetes, which is prone to develop into end-stage renal disease, and early diagnosis and treatment is the key to effective management of dn. biomarkers have important clinical significance in the diagnosis and treatment of dn and have attracted extensive attention from researchers in recent years. the aim of this study was to visualize the field of biomarker research in dn through bibliometric analysis, to summarize the current status and predict future trends of this field, with a view to providing valuable insights for scholars and policy makers. | medicine | eng | 2024 | Nov | Li Qin, Xie Yafei, Zuo Meiying, Li Fang | hunan university of medicine, huaihua, china., the first clinical medical college of lanzhou university, lanzhou, china., the first clinical medical college of lanzhou university, lanzhou, china., hunan university of medicine, huaihua, china. | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | hunan university of medicine, lanzhou university, lanzhou university, hunan university of medicine | Unknown | hunan university | hunan university | 351–400 | 30.4 |
| 54 | 53 | assessment of frontal qrs-t angle in distinguishing mild and severe acute pancreatitis in emergency department: a retrospective study. | acute pancreatitis (ap) is a disease that poses significant health risks with potential severe outcomes. identifying markers for severity can aid in early intervention and improve prognoses. this study, conducted in the emergency department, investigates the qrs-t angle as a potential indicator of severity in patients with acute pancreatitis. this retrospective study included 367 patients diagnosed with ap, classified as either mild acute pancreatitis or severe acute pancreatitis based on ranson criteria. the qrs-t angle was measured using standard 12-lead electrocardiogram, and the data were analyzed to compare the qrs-t angles between the mild acute pancreatitis and severe acute pancreatitis groups. this research adhered to the guidelines outlined in the strengthening the reporting of observational studies in epidemiology statement. the study included 367 patients, 94% (n = 345) had mild pancreatitis while 6% (n = 22) had severe pancreatitis. severe cases had a significantly higher median age (p < .001) and higher rates of hypertension and diabetes mellitus (p = .027, p = .011). severe cases also had higher ranson scores (3 [iqr 3-3.25] vs 1 [iqr 1-2], p < .001) and longer hospital stays (6 [iqr 2.75-11.5] days vs 3 [2-5] days, p = .029). additionally, severe pancreatitis group showed higher qrs-t angle (p < .001), higher rates of abnormal qrs angles (31.8% vs 10.1%, p = .002), and qrs-t angles (31.8% vs 8.1%, p < .001). the qrs-t angle may serve as a valuable clinical tool for differentiating between mild and severe forms of acute pancreatitis. this could potentially help clinicians in stratifying patients according to their risk and tailoring their management accordingly. | medicine | eng | 2024 | Nov | Aydoğdu Umaç Gülbin, Yilmaz Sarper | department of emergency medicine, izmir city hospital, izmir, turkey., department of emergency medicine, university of health sciences, kartal dr. lutfi kirdar city hospital, istanbul, turkey. | medicine | medicine | 0025-7974 | 1536-5964 | 1.3 | 1.6 | MEDICINE, GENERAL & INTERNAL|Q2|143/325 | department of emergency medicine, izmir city hospital, department of emergency medicine, university of health sciences, kartal dr. lutfi kirdar city hospital | retrospective study | unknown | |||
| 55 | 54 | area deprivation index impact on type 2 diabetes outcomes in a regional health plan. | rates of attainment of high-quality diabetes care have been shown to be lower for those living in more disadvantaged and rural areas. diabetes management relies on access to care and is impacted by physical, social, and economic factors. area deprivation index (adi) is one way to quantify geographic disparities in aggregate. we aimed to investigate how adi impacts outcomes in members with type 2 diabetes enrolled in a large, regional health plan. | journal of managed care & specialty pharmacy | eng | 2024 | Dec | Laffey Taylor N, Marr David, Modany Ashley, McGraw Molly, Mounarath Tavvy, Bryk Andrew, Christian Nicholas, Good Chester | upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa., upmc health plan, pittsburgh, pa. | journal of managed care & specialty pharmacy | j manag care spec ph | 2376-0540 | 2376-1032 | 2.3 | 2.3 | PHARMACOLOGY & PHARMACY|Q3|199/354 | upmc health plan, upmc health plan, upmc health plan, upmc health plan, upmc health plan, upmc health plan, upmc health plan, upmc health plan | diabetes management | unknown | |||
| 56 | 55 | synthesis and evaluation of antidiabetic potential of gliptin-based hybrid scaffolds. | dipeptidyl peptidase-4 (dpp4) inhibitors are promising therapeutic targets for the treatment of a catastrophic disease, especially diabetes mellitus (dm), which contributed to a massive rate of mortality. this research work succinctly covers the significance and vital role of gliptins in diabetes management and in the potential areas of further antidiabetic research, making it a strong drug candidate for antidiabetic drug development. we illustrated herein molecular docking, synthesis, and biological evaluation of selected potent synthesized molecules. additionally, all the potent compounds were characterized by means of mass and nmr spectral analysis, whereas the purity of these molecules were assessed by hplc method. in order to determine the efficacy and cytotoxicity of synthesized gliptin-based scaffolds, in-vitro anti-oxidant and mtt assays with the implantation of dpph and thp-1 cell lines, respectively, were performed. the results data disclose the anti-oxidant and biosafety potential of the newly schemed compounds. based on in-vitro screening outcomes, only a derivative that exhibited potent efficacy was selected and subjected to an in-vivo study. among them, compounds 6 and 12 are the most potent ones, which exhibited % radical scavenge of 89.38 % and 91.58 % related to standard ascorbic acid (91.58 %). surprisingly, these compounds also exhibited excellent anti-diabetic efficacy at a dose of 4 mg/kg in an in-vivo animal model. in conclusion, all studies suggested that the titled molecules could be promising lead compounds for the treatment of patients with type 2 diabetes mellitus. | chemistry & biodiversity | eng | 2024 | Nov | Yahya Shaikh, Gour Vivek Kumar, Sangshetti Jaiprakash, Deshpande Prathamesh, Shafeeque Mohd, Sharma Nisha, Choudhary Akram, Shahar Yar M | department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, 110062, new delhi., department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, 110062, new delhi., y. b. chavan college of pharmacy, dr. rafiq zakaria campus, rauza baugh, aurangabad, 431001, india., department of pharmaceutical chemistry, deogiri college, aurangabad, maharashtra, 431001, india., department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, 110062, new delhi., department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, 110062, new delhi., department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, 110062, new delhi., department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, 110062, new delhi. | chemistry & biodiversity | chem biodivers | 1612-1872 | 1612-1880 | 2.3 | 2.5 | CHEMISTRY, MULTIDISCIPLINARY|Q3|121/230 | department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, y. b. chavan college of pharmacy, dr. rafiq zakaria campus, department of pharmaceutical chemistry, deogiri college, department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard, department of pharmaceutical chemistry, school of pharmaceutical education and research, jamia hamdard | in-vivo study | chavan college | |||
| 57 | 56 | timing of meal replacement on body weight: a multicenter open-labeled randomized trial. | we aim to evaluate the effects of partial meal replacement (mr) with different timing of mr on body weight in chinese adults. | endocrine | eng | 2024 | Nov | Wang Jialu, Xiang Yi, Chen Zhiqi, Lu Wenyi, Zhou Yiquan, Mao Xiaomeng, Tang Molian, Zou Jing, Song Anqi, Tang Qingya, Xu Renying | department of clinical nutrition, ren ji hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, xin hua hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, ren ji hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, xin hua hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, ren ji hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, xin hua hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, ren ji hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, xin hua hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, ren ji hospital, shanghai jiao tong university school of medicine, shanghai, china., department of clinical nutrition, xin hua hospital, shanghai jiao tong university school of medicine, shanghai, china. tangqingya@xinhuamed.com.cn., department of clinical nutrition, ren ji hospital, shanghai jiao tong university school of medicine, shanghai, china. 721001735@shsmu.edu.cn. | endocrine | endocrine | 1355-008X | 1559-0100 | 3.0 | 3.1 | ENDOCRINOLOGY & METABOLISM|Q2|88/186 | shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine, shanghai jiao tong university school of medicine | Unknown | tong university | |||
| 58 | 57 | cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the uk biobank cohort study. | to investigate associations between glycaemic measures (hba1c, random glucose), and grip strength (gs) in adults without prevalent diabetes. | european geriatric medicine | eng | 2024 | Nov | Granic Antoneta, Cooper Rachel, Hurst Christopher, Hillman Susan J, Dodds Richard M, Witham Miles D, Sayer Avan A | age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk. antoneta.granic@newcastle.ac.uk., age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk., age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk., age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk., age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk., age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk., age research group, translational and clinical research institute, faculty of medical sciences, newcastle university, the health innovation neighbourhood, biomedical research building, newcastle upon tyne, ne4 5pl, uk. | european geriatric medicine | eur geriatr med | 1878-7649 | 1878-7657 | 3.5 | 3.2 | GERIATRICS & GERONTOLOGY|Q2|29/74 | faculty of medical sciences, newcastle university, faculty of medical sciences, newcastle university, faculty of medical sciences, newcastle university, faculty of medical sciences, newcastle university, faculty of medical sciences, newcastle university, faculty of medical sciences, newcastle university, faculty of medical sciences, newcastle university | Unknown | newcastle university | newcastle university | 168 | 41.1 |
| 59 | 58 | a systematic review on dysphagia treatments for persons living with dementia. | dysphagia in persons living with dementia (plwd) is raising concern due to the absence of swallowing treatments specific to this population. dysphagia can result in detrimental effects, such as malnutrition, dehydration, and aspiration pneumonia. this systematic review aimed to evaluate the existing literature on dysphagia management of plwd and reveal their limitations to facilitate clinical practitioners in decision-making. | european geriatric medicine | eng | 2024 | Nov | Chan Charis Tsz Wun, Wu Tsz Yin, Cheng Ivy | academic unit of human communication, learning and development, faculty of education, the university of hong kong, room 766, 7/f, meng wah complex, hong kong, china., academic unit of human communication, learning and development, faculty of education, the university of hong kong, room 766, 7/f, meng wah complex, hong kong, china., academic unit of human communication, learning and development, faculty of education, the university of hong kong, room 766, 7/f, meng wah complex, hong kong, china. ikycheng@hku.hk. | european geriatric medicine | eur geriatr med | 1878-7649 | 1878-7657 | 3.5 | 3.2 | GERIATRICS & GERONTOLOGY|Q2|29/74 | faculty of education, the university of hong kong, faculty of education, the university of hong kong, faculty of education, the university of hong kong | systematic review | the university | |||
| 60 | 59 | gc-ms analysis of polysaccharides from an intergeneric hybrid of pleurotus florida and cordyceps militaris: a comparative study. | edible and medicinal mushrooms are valuable sources of polysaccharides, known for their dual roles as immunostimulants and immunosuppressants. this study aimed to enhance polysaccharide content by fusing two mushroom species, p. florida and c. militaris, while exploring their antioxidant and antibacterial potential. these mushrooms have diverse health benefits, including lowering high cholesterol, providing anti-inflammatory effects, supporting diabetes management, aiding in cancer treatment, and enhancing the efficacy of covid-19 vaccines. successful hyphal fusion was achieved, and optimal culture conditions were determined using response surface methodology. the hybrids exhibited superior growth compared to the parental strains. hyphal fusion improved several attributes, resulting in diverse hybrids with increased biomass and metabolite production. ftir analysis confirmed the presence of exopolysaccharides, with concentrations measured at 28.4 g/l (p1), 31.50 g/l (cd), and 36.74 g/l (f3). gc-ms analysis identified various bioactive metabolites, including a higher concentration of dimethyl palmitamine in the hybrid, a novel compound, butanenitrile, 2-(methoxymethoxy), which was not found in the parental strains. these compounds are likely responsible for the enhanced antimicrobial and antioxidant activities. | applied biochemistry and biotechnology | eng | 2024 | Nov | Meshram Varsha, Thakur Prachi, Jadhav Shailesh Kumar, Chandrawanshi Nagendra Kumar | school of studies in biotechnology, pt. ravishankar shukla university, raipur, chhattisgarh, 492 010, india., st. thomas college, ruabandha, bhilai, durg, chhattisgarh, 490 006, india., school of studies in biotechnology, pt. ravishankar shukla university, raipur, chhattisgarh, 492 010, india., school of studies in biotechnology, pt. ravishankar shukla university, raipur, chhattisgarh, 492 010, india. chandrawanshi11@gmail.com. | applied biochemistry and biotechnology | appl biochem biotech | 0273-2289 | 1559-0291 | 3.1 | 2.9 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY|Q2|82/174 | school of studies in biotechnology, ravishankar shukla university, st. thomas college, school of studies in biotechnology, ravishankar shukla university, school of studies in biotechnology, ravishankar shukla university | response surface methodology | shukla university | |||
| 61 | 60 | cratylia mollis lectin reduces inflammatory burden induced by multidrug-resistant staphylococcus aureus in diabetic wounds. | in diabetes, tissue repair is impaired, increasing susceptibility to staphylococcus aureus infections, a pathogen commonly found in wounds. the emergence of s. aureus strains that are highly resistant to antimicrobial agents highlights the urgent need for alternative therapeutic options. one promising candidate is cramoll (cratylia mollis seed lectin), known for its immunomodulatory, mitogenic, and healing properties. however, its efficacy in infected diabetic wounds remains unexplored. this study evaluated the effects of topical cramoll treatment on diabetic wounds infected by s. aureus. diabetic swiss mice (induced by streptozotocin) were subjected to an 8-mm wound on the back and subsequently infected with a suspension of multidrug-resistant s. aureus. during the treatment period, the wounds were clinically evaluated for inflammation and the area of injury. after seven days, samples were collected from the wounds to quantify the bacterial load and histopathological and immunological analyses. wounds infected by s. aureus exhibited more pronounced areas and severity indices, which were significantly reduced by cramoll treatment (p < 0.05). histopathological analysis revealed a reduction in inflammatory cells and an increase in revascularization with cramoll treatment (p < 0.05). cramoll also promoted greater collagen production compared to controls (p < 0.05). furthermore, cramoll treatment significantly reduced the s. aureus load in wounds (p < 0.0001), decreased tnf-α and il-6 levels in infected wounds, and increased erk pathway activation (p < 0.05). in conclusion, cramoll lectin improves the healing of diabetic wounds, and these results contribute to the understanding of cramoll healing mechanisms, reinforcing its potential as a healing agent in various clinical conditions. | histochemistry and cell biology | eng | 2024 | Nov | Dos Santos Silva Lucas, Dos Santos Castelo Branco Simeone Júlio, Silva Izadora Souza Soeiro, Paiva Miria Yasmim Miranda, Vila Nova Beatriz Gomes, de Matos Chaves Lima Carlos Emanuel, de Oliveira Weslley Felix, de Paiva Felipe Eduardo Alves, Paiva Patrícia Maria Guedes, de Souza Monteiro Andrea, Teixeira Claudener Souza, Cardoso Cléver Gomes, Dos Santos Correia Maria Tereza, Nascimento da Silva Luís Cláudio | laboratório de patogenicidade microbiana, universidade ceuma, são luís, 65075-120, brazil., laboratório de bioquímica de proteínas, centro de biociências, universidade federal de pernambuco, recife, 50740-570, brazil., laboratório de patogenicidade microbiana, universidade ceuma, são luís, 65075-120, brazil., laboratório de patogenicidade microbiana, universidade ceuma, são luís, 65075-120, brazil., laboratório de patogenicidade microbiana, universidade ceuma, são luís, 65075-120, brazil., laboratório de odontologia, universidade ceuma, são luís, 65075-120, brazil., laboratório de bioquímica de proteínas, centro de biociências, universidade federal de pernambuco, recife, 50740-570, brazil., departamento de histologia, embriologia e biologia celular, universidade federal de goiás, goiânia, 74690-900, brazil., laboratório de bioquímica de proteínas, centro de biociências, universidade federal de pernambuco, recife, 50740-570, brazil., laboratório de microbiologia aplicada, universidade ceuma, são luís, 65075-120, brazil., centro de ciências agrárias e da biodiversidade, universidade federal do cariri, crato, ceará, 63130-025, brazil., departamento de histologia, embriologia e biologia celular, universidade federal de goiás, goiânia, 74690-900, brazil., laboratório de bioquímica de proteínas, centro de biociências, universidade federal de pernambuco, recife, 50740-570, brazil., laboratório de patogenicidade microbiana, universidade ceuma, são luís, 65075-120, brazil. luisclaudionsilva@yahoo.com.br. | histochemistry and cell biology | histochem cell biol | 0948-6143 | 1432-119X | 2.1 | 2.7 | MICROSCOPY|Q2|3/8 | universidade ceuma, centro de biociências, universidade federal de pernambuco, universidade ceuma, universidade ceuma, universidade ceuma, universidade ceuma, centro de biociências, universidade federal de pernambuco, universidade federal de goiás, centro de biociências, universidade federal de pernambuco, universidade ceuma, universidade federal do cariri, universidade federal de goiás, centro de biociências, universidade federal de pernambuco, universidade ceuma | Unknown | unknown | |||
| 62 | 61 | the relationship of changes in insulin demand and insulin adequacy over the life course. | insulin requirements in the human body undergo continuous changes in response to growth and development. we assessed the life course relationships between insulin demand and insulin adequacy. | diabetologia | eng | 2024 | Nov | Zhang Yingchai, Tam Claudia H T, Lau Eric S H, Ng Noel Y H, Yang Aimin, Fan Baoqi, Wu Hongjiang, Lim Cadmon K P, Chow Elaine Y K, Luk Andrea O Y, Kong Alice P S, Tam Wing Hung, Chan Juliana C N, Ma Ronald C W | department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of obstetrics and gynaecology, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china., department of medicine and therapeutics, prince of wales hospital, the chinese university of hong kong, hong kong, china. rcwma@cuhk.edu.hk. | diabetologia | diabetologia | 0012-186X | 1432-0428 | 8.4 | 9.1 | ENDOCRINOLOGY & METABOLISM|Q1|12/186 | prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, prince of wales hospital, the chinese university of hong kong, prince of wales hospital, the chinese university of hong kong | Unknown | chinese university | |||
| 63 | 62 | postprandial hypoglycaemia after gastric bypass in type 2 diabetes: pathophysiological mechanisms and clinical implications. | postprandial hypoglycaemia (pphg) is a frequent late complication of roux-en-y gastric bypass (rygb) in people without diabetes. we aimed to examine the pathogenetic mechanisms of pphg and its clinical consequences in people with a history of type 2 diabetes. | diabetologia | eng | 2024 | Nov | Tricò Domenico, Sacchetta Luca, Rebelos Eleni, Cimbalo Noemi, Chiriacò Martina, Moriconi Diego, Nesti Lorenzo, Nesti Giulia, Frascerra Silvia, Scozzaro Maria T, Daniele Giuseppe, Baldi Simona, Mari Andrea, Nannipieri Monica, Natali Andrea | department of clinical and experimental medicine, university of pisa, pisa, italy. domenico.trico@unipi.it., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., institute of neuroscience, national research council, padua, italy., department of clinical and experimental medicine, university of pisa, pisa, italy., department of clinical and experimental medicine, university of pisa, pisa, italy. | diabetologia | diabetologia | 0012-186X | 1432-0428 | 8.4 | 9.1 | ENDOCRINOLOGY & METABOLISM|Q1|12/186 | university of pisa, university of pisa, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, university of pisa, pisa, italy, institute of neuroscience, national research council, university of pisa, pisa, italy, university of pisa, pisa, italy | Unknown | unknown | |||
| 64 | 63 | protective effect and molecular mechanism of mesenchymal stem cell-derived extracellular vesicles in diabetic foot ulcers. | this study explores the protective mechanism of mesenchymal stem cell-derived extracellular vesicles (msc-evs) in diabetic foot ulcer (dfu). human umbilical cord mscs (hucmscs) were identified via osteogenesis and adipogenic differentiation, as well as flow cytometry. evs were isolated from hucmscs and characterized using transmission electron microscopy, nanoparticle tracking analysis, and western blotting. fluorescence microscopy revealed the uptake of pkh67-labeled evs and cy3-labeled microrna-21-5p (mir-21-5p) by human skin fibroblasts (hsfs). evs were cocultured with hsfs, and cell proliferation and migration were assessed using cell counting kit-8, colony formation, scratch, and transwell assays. mir-21-5p overexpression in evs was evaluated for its role in promoting hsf functions. the expression levels of mir-21-5p, krüppel-like factor 6 (klf6), α-smooth muscle actin, and collagen type i alpha 1 chain were analyzed via quantitative real-time pcr and western blotting. the interaction between mir-21-5p and klf6 was confirmed through a dual-luciferase reporter gene assay. hucmsc-derived evs enhanced the proliferation and migration of hsfs under high glucose by delivering mir-21-5p, which targeted and inhibited klf6. overexpression of klf6 counteracted the pro-proliferative and migratory effects of evs carrying mir-21-5p. overall, these findings suggest that hucmsc-evs promote hsf proliferation and migration by downregulating klf6 via mir-21-5p delivery, offering a potential therapeutic strategy for dfu. | cellular reprogramming | eng | 2024 | Nov | Zhao Jian, Gu Yan, Hou Peng | department of vascular surgery, tianjin first central hospital, tianjin, china., department of vascular surgery, tianjin first central hospital, tianjin, china., department of vascular surgery, tianjin first central hospital, tianjin, china. | cellular reprogramming | cell reprogram | 2152-4971 | 2152-4998 | 1.2 | 1.7 | GENETICS & HEREDITY|Q4|162/191 | department of vascular surgery, tianjin first central hospital, department of vascular surgery, tianjin first central hospital, department of vascular surgery, tianjin first central hospital | flow cytometry | unknown | |||
| 65 | 64 | baseline characteristics of the discover ckd prospective cohort. | real-world data from patients with chronic kidney disease (ckd) are limited, particularly regarding clinical management, treatment patterns and health-related quality of life (hrqol) in the context of new therapies and updated standard of care guidelines. | advances in therapy | eng | 2024 | Nov | Pollock Carol, Carrero Juan-Jesus, Kanda Eiichiro, Ofori-Asenso Richard, Chen Hungta, Garcia Sanchez Juan Jose, Pentakota Surendra, Pecoits-Filho Roberto, Fishbane Steven, Lam Carolyn S P, Kashihara Naoki, Wheeler David C | kolling institute, royal north shore hospital, university of sydney, 10 westbourne st, st leonards, sydney, nsw, 2064, australia. carol.pollock@sydney.edu.au., department of medical epidemiology and biostatistics, karolinska institutet, solna, sweden., department of health data science, kawasaki medical school, kurashiki, okayama, japan., cardiovascular, renal, metabolism epidemiology, biopharmaceuticals medical, astrazeneca, cambridge, uk., medical and payer evidence statistics, biopharmaceuticals medical, astrazeneca, gaithersburg, md, usa., global market access and pricing, astrazeneca, barcelona, spain., global medical affairs, biopharmaceuticals medical, astrazeneca, cambridge, uk., school of medicine, pontifical catholic university of parana, curitiba, brazil., division of nephrology, zucker school of medicine, great neck, ny, usa., national heart centre singapore, singapore, singapore., department of nephrology, kawasaki medical school, okayama, japan., department of renal medicine, university college london, london, uk. | advances in therapy | adv ther | 0741-238X | 1865-8652 | 3.4 | 4.0 | PHARMACOLOGY & PHARMACY|Q2|105/354 | royal north shore hospital, university of sydney, karolinska institutet, kawasaki medical school, school of medicine, pontifical catholic university of parana, zucker school of medicine, national heart centre singapore, kawasaki medical school, university college london | treatment patterns | karolinska institute | karolinska institute | 50 | 67.9 |
| 66 | 65 | tight and stable glucose control is associated with better prognosis in patients hospitalized for covid-19 and pneumonia. | to investigate possible associations of glucose patterns with outcomes of corona virus disease 19 (covid-19) using continuous glucose monitoring (cgm) in 43 patients hospitalized for covid-19 mild-to-moderate pneumonia, regardless of diabetes. | acta diabetologica | eng | 2024 | Nov | Caretto Amelia, Di Terlizzi Gaetano, Pedone Erika, Pennella Renato, De Cobelli Francesco, Tresoldi Moreno, Scavini Marina, Bosi Emanuele, Laurenzi Andrea | diabetes research institute, irccs san raffaele scientific institute, milan, italy., unit of general medicine and advanced care, irccs san raffaele scientific institute, milan, italy., diabetes research institute, irccs san raffaele scientific institute, milan, italy., department of radiology, irccs san raffaele scientific institute, milan, italy., department of radiology, irccs san raffaele scientific institute, milan, italy., unit of general medicine and advanced care, irccs san raffaele scientific institute, milan, italy., diabetes research institute, irccs san raffaele scientific institute, milan, italy., diabetes research institute, irccs san raffaele scientific institute, milan, italy. bosi.emanuele@hsr.it., diabetes research institute, irccs san raffaele scientific institute, milan, italy. | acta diabetologica | acta diabetol | 0940-5429 | 1432-5233 | 3.1 | 3.4 | ENDOCRINOLOGY & METABOLISM|Q2|85/186 | diabetes research institute, irccs san raffaele scientific institute, unit of general medicine and advanced care, irccs san raffaele scientific institute, diabetes research institute, irccs san raffaele scientific institute, department of radiology, irccs san raffaele scientific institute, department of radiology, irccs san raffaele scientific institute, unit of general medicine and advanced care, irccs san raffaele scientific institute, diabetes research institute, irccs san raffaele scientific institute, diabetes research institute, irccs san raffaele scientific institute, diabetes research institute, irccs san raffaele scientific institute | Unknown | research institute | |||
| 67 | 66 | automated insulin delivery systems for the management of insulin therapy in post-transplant diabetes mellitus: a case series from a single center population. | no abstract | acta diabetologica | eng | 2024 | Nov | Grancini Valeria, Cogliati Irene, Gaglio Alessia, Alfieri Carlo, Castellano Giuseppe, Orsi Emanuela, Resi Veronica | endocrinology unit, fondazione irccs ca' granda- ospedale maggiore policlinico milano, via francesco sforza 35, 20122, milan, italy. valeria.grancini@policlinico.mi.it., endocrinology unit, fondazione irccs ca' granda- ospedale maggiore policlinico milano, via francesco sforza 35, 20122, milan, italy., endocrinology unit, fondazione irccs ca' granda- ospedale maggiore policlinico milano, via francesco sforza 35, 20122, milan, italy., nephrology, dialysis and transplantation, fondazione irccs ca' granda ospedale maggiore policlinico, 20122, milan, italy., nephrology, dialysis and transplantation, fondazione irccs ca' granda ospedale maggiore policlinico, 20122, milan, italy., endocrinology unit, fondazione irccs ca' granda- ospedale maggiore policlinico milano, via francesco sforza 35, 20122, milan, italy., endocrinology unit, fondazione irccs ca' granda- ospedale maggiore policlinico milano, via francesco sforza 35, 20122, milan, italy. | acta diabetologica | acta diabetol | 0940-5429 | 1432-5233 | 3.1 | 3.4 | ENDOCRINOLOGY & METABOLISM|Q2|85/186 | fondazione irccs ca' granda- ospedale maggiore policlinico milano, fondazione irccs ca' granda- ospedale maggiore policlinico milano, fondazione irccs ca' granda- ospedale maggiore policlinico milano, fondazione irccs ca' granda ospedale maggiore policlinico, fondazione irccs ca' granda ospedale maggiore policlinico, fondazione irccs ca' granda- ospedale maggiore policlinico milano, fondazione irccs ca' granda- ospedale maggiore policlinico milano | Unknown | unknown | |||
| 68 | 67 | multi-omics mechanical analysis of gut microbiota, carboxylic acids, and cardiac gene expression interaction triggering diabetic cardiomyopathy. | it is well known that gut microbial imbalance is a potential factor for the occurrence and development of diabetes mellitus (dm) and its complications. moreover, the heart and gut microbiota can regulate each other through the gut-metabolite-heart axis. in this study, metagenomics, metabolomics, and transcriptomics were chosen to sequence the changes in gut microbiota, serum metabolite levels, and differentially expressed genes (degs) in leptin receptor-deficient db/db mice and analyze the correlation between serum metabolites and gut microbiota or degs. according to the results, there were significant differences in the 1,029 cardiac genes and 353 serum metabolites in diabetic mice of the db/db group, including degs enriched in the ppar signaling pathway and increased short-chain carboxylic acids (cas), when compared with the normal db/m group. according to metagenomics, the gut microbiota of mice in the db/db group were disrupted, and particularly lachnospiraceae bacteria and oscillospiraceae bacteria significantly decreased. also, according to the pearson correlation analysis, a significant positive correlation was found between cas and ppar signaling pathway-related degs, and a negative correlation was found between cas and the abundance of the above-mentioned species. to sum up, type 2 diabetes mellitus (t2dm) can upregulate the expression of partial cardiac genes through the levels of serum short-chain cas affected by gut microbiota, thus playing a role in the occurrence and development of diabetic cardiomyopathy (dcm). | msystems | eng | 2024 | Nov | Shi Meixin, Zhao Bingbing, Cai Wenjie, Yuan Hui, Liang Xiao, Li Zhitao, Liu Xinyu, Jin Ye, Liu Xi, Wei Can | department of pathophysiology, harbin medical university, harbin, heilongjiang, china., department of pathophysiology, harbin medical university, harbin, heilongjiang, china., department of pathophysiology, harbin medical university, harbin, heilongjiang, china., school of basic medical sciences, mudanjiang medical university, mudanjiang, heilongjiang, china., department of cardiology, the first affiliated hospital of harbin medical university, harbin, heilongjiang, china., department of pathophysiology, harbin medical university, harbin, heilongjiang, china., school of basic medical sciences, mudanjiang medical university, mudanjiang, heilongjiang, china., department of general surgery, key laboratory of hepatosplenic surgery, ministry of education, the first affiliated hospital of harbin medical university, harbin, heilongjiang, china., department of cardiology, ordos central hospital, ordos, china., department of general surgery, key laboratory of hepatosplenic surgery, ministry of education, the first affiliated hospital of harbin medical university, harbin, heilongjiang, china. | msystems | msystems | 2379-5077 | 2379-5077 | 5.0 | 6.1 | MICROBIOLOGY|Q1|29/161 | harbin medical university, harbin medical university, harbin medical university, school of basic medical sciences, mudanjiang medical university, harbin medical university, harbin medical university, school of basic medical sciences, mudanjiang medical university, ministry of education, harbin medical university, ordos central hospital, ministry of education, harbin medical university | metagenomics | medical university | |||
| 69 | 68 | utility of anthropometric indexes for detecting metabolic syndrome in resource-limited regions of northwestern china: cross-sectional study. | anthropometric indexes offer a practical approach to identifying metabolic syndrome (mets) and its components. however, there is a scarcity of research on anthropometric indexes tailored to predict mets in populations from resource-limited regions. | jmir public health and surveillance | eng | 2024 | Nov | Yang Danyu, Ma Ling, Cheng Yin, Shi Hongjuan, Liu Yining, Shi Chao | people's hospital of ningxia hui autonomous region, ningxia medical university, no.301 zhengyuan north street, yinchuan, 750001, china, 86 10-5920152, 86 10-5920017., school of public health, ningxia medical university, yinchuan, china., school of public health, ningxia medical university, yinchuan, china., school of public health, ningxia medical university, yinchuan, china., people's hospital of ningxia hui autonomous region, ningxia medical university, no.301 zhengyuan north street, yinchuan, 750001, china, 86 10-5920152, 86 10-5920017., people's hospital of ningxia hui autonomous region, ningxia medical university, no.301 zhengyuan north street, yinchuan, 750001, china, 86 10-5920152, 86 10-5920017. | jmir public health and surveillance | jmir public hlth sur | 2369-2960 | 2369-2960 | 3.5 | 4.7 | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH|Q1|84/403 | ningxia hui autonomous region, ningxia medical university, ningxia medical university, ningxia medical university, ningxia medical university, ningxia hui autonomous region, ningxia medical university, people's hospital of ningxia hui autonomous region, ningxia medical university | research | medical university | |||
| 70 | 69 | analyzing quinoa seeds: lc-ms/ms and gc-ms/ms approaches for identifying a nutrient-rich functional food in alzheimer's and diabetes care. | quinoa is a versatile, nutrient-dense, gluten-free pseudocereal, increasingly recognized for its potential health benefits, particularly in managing diabetes mellitus and alzheimer's disease-two conditions with growing links. recent research on 14 quinoa genotypes explored fatty oil composition and bioactive potential of quinoa extracts. linoleic acid was predominant fatty acid (46.60%-56.33%), while alanine was the most concentrated amino acid across all active extracts (192.4887-1578.0355 nmol/ml). french vanilla hexane extract exhibited the strongest α-glucosidase inhibition (75.71%), with santa ana hexane extract showing the highest α-amylase inhibition (28.58%). additionally, titicaca hexane extract displayed notable acetylcholinesterase inhibition (22.22%), and moqu arochilla methanol extract had the most potent butyrylcholinesterase inhibition (47.20%). antioxidant assays revealed that salcedo and french vanilla extracts had exceptional dpph radical scavenging activity, with positive correlations found between total phenolic content and antioxidant activity (dpph, β-carotene, frap). these findings emphasize quinoa's potential as a functional food, offering significant benefits for disease management. | chemistry & biodiversity | eng | 2024 | Nov | Çoban Furkan, Yuca Hafize, Aydın Bilge, Tosun Murat, Yazıcı Abdullah, Karakaya Songül, Tan Mustafa, Özer Hakan, Atila Alptuğ | atatürk üniversitesi, field crops, erzurum, erzurum, turkey., atatürk üniversitesi, pharmacognosy, atatürk üniversitesi eczacılık fakültesi 25240 yakutiye/erzurum, erzurum, 25240, erzurum, turkey., erzincan university, pharmacognosy, erzincan, erzincan, turkey., atatürk üniversitesi, gastronomy and culinary arts, erzurum, erzurum, turkey., atatürk üniversitesi, field crops, erzurum, erzurum, turkey., ataturk university: ataturk universitesi, pharmaceutical botany, atatürk university faculty of pharmacy department of pharmacognosy, 25240, erzurum, turkey., trakya üniversitesi, park and garden plants, edirne, edirne, turkey., atatürk üniversitesi, field crops, erzurum, erzurum, turkey., atatürk üniversitesi, analytical chemistry, erzurum, erzurum, turkey. | chemistry & biodiversity | chem biodivers | 1612-1872 | 1612-1880 | 2.3 | 2.5 | CHEMISTRY, MULTIDISCIPLINARY|Q3|121/230 | atatürk üniversitesi, atatürk üniversitesi, atatürk üniversitesi, erzincan university, atatürk üniversitesi, atatürk üniversitesi, ataturk university, ataturk universitesi, atatürk university, trakya üniversitesi, atatürk üniversitesi, atatürk üniversitesi | recent research | erzincan university | |||
| 71 | 70 | a team approach to adhesive capsulitis with ultrasound guided hydrodilatation: a retrospective study. | adhesive capsulitis (ac) causes shoulder pain and limited range of motion. while ultrasound-guided suprascapular nerve block, glenohumeral joint hydrodilatation, and physical therapy are effective individually, their combined use is not well-studied. | pain management | eng | 2024 | Nov | Dakkak Michael, Genin Jason, Wichman Lauren, Zhang Chao, Patel Vikas | department of orthopaedic surgery, cleveland clinic foundation florida, weston, fl, usa., cleveland clinic foundation, cleveland, oh, usa., cleveland clinic foundation, cleveland, oh, usa., cleveland clinic foundation, cleveland, oh, usa., cleveland clinic foundation, cleveland, oh, usa. | pain management | pain manag | 1758-1869 | 1758-1877 | 1.4 | 2.2 | CLINICAL NEUROLOGY|Q4|215/277 | cleveland clinic foundation, cleveland clinic foundation, cleveland clinic foundation, cleveland clinic foundation, cleveland clinic foundation | Unknown | unknown | |||
| 72 | 71 | diabetes education program for nursing students: a systematic review and meta-analysis. | the purpose of this study was to summarise the current state of the science on diabetes mellitus education programs for nursing students. | nursing open | eng | 2024 | Dec | Ahn Jeong-Ah, Kim Eun-Mi, Lee Jung Eun, Kim Kyoung-A | college of nursing and research institute of nursing science, ajou university, suwon, south korea., college of nursing, research institute of nursing science, pusan national university, pusan, south korea., college of nursing, university of rhode island, kingston, ri, usa., college of nursing, suwon women's university, suwon, south korea. | nursing open | nurs open | 2054-1058 | 2054-1058 | 2.0 | 2.4 | NURSING|Q2|61/191 | college of nursing, research institute of nursing science, ajou university, college of nursing, research institute of nursing science, pusan national university, college of nursing, university of rhode island, college of nursing, suwon women's university | Unknown | research institute | |||
| 73 | 72 | characteristics of phage-plasmids and their impact on microbial communities. | bacteria host various foreign genetic elements, most notably plasmids and bacteriophages (or phages). historically, these two classes were seen as separate, but recent research has shown considerable interplay between them. phage-plasmids (p-ps) exhibit characteristics of both phages and plasmids, allowing them to exist extrachromosomally within bacterial hosts as plasmids, but also to infect and lyse bacteria as phages. this dual functionality enables p-ps to utilize the modes of transmission of both phage and plasmids, facilitating the rapid dissemination of genetic material, including antibiotic resistance and virulence genes, throughout bacterial populations. additionally, p-ps have been found to encode toxin-antitoxin and crispr-cas adaptive immune systems, which enhance bacterial survival under stress and provide immunity against other foreign genetic elements. despite a growing body of literature on p-ps, large gaps remain in our understanding of their ecological roles and environmental prevalence. this review aims to synthesise existing knowledge and identify research gaps on the impacts of p-ps on microbial communities. | essays in biochemistry | eng | 2024 | Nov | Sayid Ruweyda, van den Hurk Anne W M, Rothschild-Rodriguez Daniela, Herrema Hilde, de Jonge Patrick A, Nobrega Franklin L | school of biological sciences, university of southampton, southampton, uk., departments of internal and experimental vascular medicine, amsterdam umc, location amc, university of amsterdam, amsterdam; the netherlands., school of biological sciences, university of southampton, southampton, uk., departments of internal and experimental vascular medicine, amsterdam umc, location amc, university of amsterdam, amsterdam; the netherlands., departments of internal and experimental vascular medicine, amsterdam umc, location amc, university of amsterdam, amsterdam; the netherlands., school of biological sciences, university of southampton, southampton, uk. | essays in biochemistry | essays biochem | 0071-1365 | 1744-1358 | 5.6 | 7.5 | BIOCHEMISTRY & MOLECULAR BIOLOGY|Q1|56/313 | university of southampton, amsterdam umc, university of amsterdam, university of southampton, amsterdam umc, university of amsterdam, amsterdam umc, university of amsterdam, university of southampton | Unknown | unknown | |||
| 74 | 73 | the health benefits of fermented fruits and vegetables and their underlying mechanisms. | fermented fruits and vegetables are rich in phenolic compounds, minerals, and vitamins, which have potential health benefits for the prevention of many diseases such as cardiovascular disease and type 2 diabetes. there is a growing demand for the development of nondairy probiotic products based on fruits and vegetables in view of changing lifestyles (e.g., vegetarianism, veganism, and allergy to dairy products) and the rise of nutritional diet therapy. in this review, the processes and health potential of fermented fruits and vegetables are described. the study focuses on the role of bacteria and fungi in fermented fruits and vegetables, outlines the process of transformation of bioactive components, and systematically summarizes the possible mechanisms of antioxidant, anti-inflammatory, and blood pressure-lowering effects. the health effects of fermented fruits and vegetables depend mainly on the microorganisms present in the fermentation process and the bioactive components they produce, such as phenols, vitamins, and organic acids. these active compounds exert many health effects such as antioxidant, anti-inflammatory, anti-obesity, hypotensive, hypoglycemic, and other health benefits. therefore, the development of fermented foods based on fruits and vegetables can be a promising way to adapt to the market demand and to reduce the wastage of agriculturally produced fruits and vegetables. | comprehensive reviews in food science and food safety | eng | 2024 | Nov | Liu Lu, Li Guolong, Cui Lu, Cai Rui, Yuan Yahong, Gao Zhenpeng, Yue Tianli, Wang Zhouli | college of food science and engineering, northwest a&f university, xianyang, shaanxi, china., college of food science and engineering, northwest a&f university, xianyang, shaanxi, china., college of food science and engineering, northwest a&f university, xianyang, shaanxi, china., college of food science and technology, northwest university, xi'an, shaanxi, china., college of food science and technology, northwest university, xi'an, shaanxi, china., college of food science and engineering, northwest a&f university, xianyang, shaanxi, china., college of food science and technology, northwest university, xi'an, shaanxi, china., college of food science and engineering, northwest a&f university, xianyang, shaanxi, china. | comprehensive reviews in food science and food safety | compr rev food sci f | 1541-4337 | 1541-4337 | 12.0 | 15.9 | FOOD SCIENCE & TECHNOLOGY|Q1|3/173 | college of food science and engineering, northwest a&f university, college of food science and engineering, northwest a&f university, college of food science and engineering, northwest a&f university, college of food science and technology, northwest university, college of food science and technology, northwest university, college of food science and engineering, northwest a&f university, college of food science and technology, northwest university, college of food science and engineering, northwest a&f university | Unknown | f university | |||
| 75 | 74 | the user-centered design of a clinical dashboard and patient-facing app for gestational diabetes. | the number of pregnancies affected by gestational diabetes mellitus (gdm) is growing. with the increased use of smartphones and predictive modeling, a mobile health (mhealth) solution could be developed to improve care and management of gdm while streamlining care through risk stratification. | journal of diabetes science and technology | eng | 2024 | Nov | Kirkwood Jasmine R, Dickson Jane, Stevens Marryat, Manataki Areti, Lindsay Robert S, Wake Deborah J, Reynolds Rebecca M | centre for cardiovascular science, queen's medical research institute, the university of edinburgh, edinburgh, uk., medical school, university of dundee, dundee, uk., myway digital health, dundee, uk., school of computer science, university of st. andrews, st. andrews, uk., school of cardiovascular and metabolic health, the university of glasgow, edinburgh, uk., myway digital health, dundee, uk., centre for cardiovascular science, queen's medical research institute, the university of edinburgh, edinburgh, uk. | journal of diabetes science and technology | j diabetes sci techn | 1932-2968 | 1932-2968 | 4.1 | ENDOCRINOLOGY & METABOLISM|Q2|49/186 | queen's medical research institute, the university of edinburgh, university of dundee, myway digital health, university of st. andrews, the university of glasgow, myway digital health, queen's medical research institute, the university of edinburgh | Unknown | research institute | ||||
| 76 | 75 | disease risk score derivation and validation in abu dhabi, united arab emirates: a retrospective cohort study. | cardiovascular disease risk assessment is a key tool in primary prevention. the adrs (abu dhabi risk study) is a retrospective cohort study aiming to develop 10-year risk prediction equations for coronary artery disease (cad), stroke, and atherosclerotic cardiovascular disease (ascvd), and validate international risk equations. | journal of the american heart association | eng | 2024 | Nov | AlKetbi Latifa Baynouna, Nagelkerke Nico, AlAlawi Noura, Humaid Ahmed, AlKetbi Rudina, Aleissaee Hamda, AlShamsi Noura, Abdulbaqi Hanan, Fahmawee Toqa, AlHashaikeh Basil, AlDobaee Muna, AlShamsi Mariam, AlAhbabi Nayla, AlAzeezi AlYazia, Shuaib Fatima, Alnuaimi Jawaher, Mahmoud Esraa, AlDhaheri Alreem, AlMansoori Mohammed, AlKalbani Sanaa, AYahyaee Aysha, AlDerie Wesayef, Saeed Ekram, AlMarzooqi Nouf, AlHassani Ahmed, AlAhmadi Amira, Sahyouni Mohammad, AlFahmawi Farah, AlAlawi Ali, Sahalu Yusra, AlAnsari Zinab, Doucoure Khadija, Ashoor Rawan, AlShamsi Reem, AlAzeezi Maha, AlMeqbaali Fatima, Yahya Noor, AlAlawi Shamma, AlKetbi Fatima | ambulatory healthcare services abu dhabi united arab emirates., united arab emirates university al ain united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates., ambulatory healthcare services abu dhabi united arab emirates. | journal of the american heart association | j am heart assoc | 2047-9980 | 5.0 | 5.7 | CARDIAC & CARDIOVASCULAR SYSTEMS|Q1|39/220 | Unknown | Unknown | unknown | ||||
| 77 | 76 | consensus report on the use of continuous glucose monitoring in chronic kidney disease and diabetes. | this report represents the conclusions of 15 experts in nephrology and endocrinology, based on their knowledge of key studies and evidence in the field, on the role of continuous glucose monitors (cgms) in patients with diabetes and chronic kidney disease (ckd), including those receiving dialysis. the experts discussed issues related to cgm accuracy, indications, education, clinical outcomes, quality of life, research gaps, and barriers to dissemination. three main goals of management for patients with ckd and diabetes were identified: (1) greater use of cgms for better glycemic monitoring and management, (2) further research evaluating the accuracy, feasibility, outcomes, and potential value of cgms in patients with end-stage kidney disease (eskd) on hemodialysis, and (3) equitable access to cgm technology for patients with ckd. the experts also developed 15 conclusions regarding the use of cgms in this population related to cgms' unique delivery of both real-time information that can guide monitoring and management of glycemia and continuous and predictive data in this population, which is at higher risk for hypoglycemia and hyperglycemia. the group noted three major clinical gaps: (1) cgms are not routinely prescribed for patients with diabetes and ckd; (2) cgms are not approved by the united states food and drug administration (fda) for patients with diabetes who are on dialysis; and (3) cgms are not routinely available to all of those who need them because of structural barriers in the health care system. these gaps can be improved with greater stakeholder collaboration, education, and awareness brought to the use of cgm technology in ckd. | journal of diabetes science and technology | eng | 2024 | Nov | Rhee Connie M, Gianchandani Roma Y, Kerr David, Philis-Tsimikas Athena, Kovesdy Csaba P, Stanton Robert C, Drincic Andjela T, Galindo Rodolfo J, Kalantar-Zadeh Kamyar, Neumiller Joshua J, de Boer Ian H, Lind Marcus, Kim Sun H, Ayers Alessandra T, Ho Cindy N, Aaron Rachel E, Tian Tiffany, Klonoff David C | va greater los angeles healthcare system, ucla david geffen school of medicine, los angeles, ca, usa., cedars-sinai health systems, los angeles, ca, usa., center for health systems research, sutter health, santa barbara, ca, usa., scripps whittier diabetes institute, san diego, ca, usa., the university of tennessee health science center, memphis, tn, usa., joslin diabetes center, beth israel deaconess medical center, harvard medical school, boston, ma, usa., university of nebraska medical center, omaha, ne, usa., miller school of medicine, university of miami, miami, fl, usa., harbor-ucla medical center, the lundquist institute, torrance, ca, usa., washington state university, spokane, wa, usa., university of washington, seattle, wa, usa., institute of medicine, university of gothenburg, gothenburg, sweden., stanford university school of medicine, stanford, ca, usa., diabetes technology society, burlingame, ca, usa., diabetes technology society, burlingame, ca, usa., diabetes technology society, burlingame, ca, usa., diabetes technology society, burlingame, ca, usa., diabetes research institute, mills-peninsula medical center, san mateo, ca, usa. | journal of diabetes science and technology | j diabetes sci techn | 1932-2968 | 1932-2968 | 4.1 | ENDOCRINOLOGY & METABOLISM|Q2|49/186 | va greater los angeles healthcare system, ucla david geffen school of medicine, cedars-sinai health systems, center for health systems research, sutter health, the university of tennessee health science center, beth israel deaconess medical center, harvard medical school, university of nebraska medical center, miller school of medicine, university of miami, harbor-ucla medical center, the lundquist institute, washington state university, university of washington, university of gothenburg, stanford university school of medicine, diabetes technology society, diabetes technology society, diabetes technology society, diabetes technology society, mills-peninsula medical center | Unknown | geffen school | ||||
| 78 | 77 | the incidence of pancreatic cancer in women with a brca1 or brca2 mutation. | the lifetime risk of pancreatic cancer in women with a germline mutation in brca1 and brca2 is not well established. in an international prospective cohort of female carriers of brca1 and brca2 mutations, the cumulative incidence of pancreatic cancer from age 40 until 80 years was estimated. | cancer | eng | 2024 | Nov | Katona Bryson W, Lubinski Jan, Pal Tuya, Huzarski Tomasz, Foulkes William D, Moller Pal, Eisen Andrea, Randall Armel Susan, Neuhausen Susan L, Raj Rebecca, Aeilts Amber, Singer Christian F, Bordeleau Louise, Karlan Beth, Olopade Olufunmilayo, Tung Nadine, Zakalik Dana, Kotsopoulos Joanne, Fruscio Robert, Eng Charis, Sun Ping, Narod Steven A | basser center for brca and division of gastroenterology and hepatology, university of pennsylvania perelman school of medicine, philadelphia, pennsylvania, usa., international hereditary cancer center, pomeranian medical university, szczecin, poland., vanderbilt-ingram cancer center, vanderbilt university medical center, nashville, tennessee, usa., international hereditary cancer center, pomeranian medical university, szczecin, poland., department of human genetics, mcgill university, montreal, quebec, canada., institute of cancer research, the norwegian radium hospital, oslo university hospital, oslo, norway., sunnybrook regional cancer centre, toronto, ontario, canada., department of obstetrics and gynecology, university of toronto, toronto, ontario, canada., department of population sciences, city of hope, duarte, california, usa., women's college research institute, toronto, ontario, canada., comprehensive cancer center, the ohio state university medical center, columbus, ohio, usa., department of obstetrics and gynecology and comprehensive cancer center, medical university of vienna, vienna, austria., department of oncology, juravinski cancer centre, hamilton, ontario, canada., department of obstetrics and gynecology, david geffen school of medicine, university of california los angeles, los angeles, california, usa., department of medicine and human genetics, university of chicago, chicago, illinois, usa., cancer risk and prevention program, beth israel deaconess medical center, boston, massachusetts, usa., cancer genetics program, beaumont hospital, royal oak, michigan, usa., women's college research institute, toronto, ontario, canada., department of medicine and surgery, university of milan bicocca, irccs san gerardo, monza, italy., center for personalized genetic healthcare, genomic medicine institute, cleveland clinic, cleveland, ohio, usa., women's college research institute, toronto, ontario, canada., women's college research institute, toronto, ontario, canada., No Affiliation | cancer | cancer-am cancer soc | 0008-543X | 1097-0142 | 6.1 | 6.7 | ONCOLOGY|Q1|49/322 | university of pennsylvania, pomeranian medical university, vanderbilt university medical center, pomeranian medical university, mcgill university, the norwegian radium hospital, oslo university hospital, sunnybrook regional cancer centre, university of toronto, the ohio state university medical center, medical university of vienna, juravinski cancer centre, david geffen school of medicine, university of california los angeles, university of chicago, beth israel deaconess medical center, beaumont hospital, university of milan bicocca, irccs san gerardo, cleveland clinic | international prospective cohort | medical university | |||
| 79 | 78 | population health strategies for health equity in chronic kidney disease management. | chronic kidney disease (ckd) is a widespread health issue, affecting one out of every 10 adults. this prevalence is even higher among vulnerable and underserved populations, including low-income individuals, racial and ethnic minorities, and immigrants. urban areas such as new york city and los angeles county offer municipal safety-net healthcare systems for these groups. | current opinion in nephrology and hypertension | eng | 2025 | Jan | Brown Christopher O, Pham Phuong-Chi, Shah Anuja, Dukkipati Ramanath, Shen Jenny, Elali Ibrahim, Dai Tiane, Raff Evan A, Kalantar-Zadeh Kamyar | los angeles county harbor-ucla medical center, torrance., olive view-ucla medical center, sylmar, california, usa., los angeles county harbor-ucla medical center, torrance., los angeles county harbor-ucla medical center, torrance., los angeles county harbor-ucla medical center, torrance., los angeles county harbor-ucla medical center, torrance., los angeles county harbor-ucla medical center, torrance., los angeles county department of health services, los angeles., los angeles county harbor-ucla medical center, torrance. | current opinion in nephrology and hypertension | curr opin nephrol hy | 1062-4821 | 1473-6543 | 2.2 | 2.7 | UROLOGY & NEPHROLOGY|Q2|54/126 | los angeles county harbor-ucla medical center, los angeles county harbor-ucla medical center, los angeles county harbor-ucla medical center, los angeles county harbor-ucla medical center, los angeles county harbor-ucla medical center, los angeles county department of health services, los angeles county harbor-ucla medical center | Unknown | unknown | |||
| 80 | 79 | prevalence of cardiovascular risk factors according to life's essential 8 in children and adolescents during the covid-19 pandemic: a systematic review and meta-analysis including 1 526 173 participants from 42 countries. | cardiovascular health is a crucial aspect of overall health. the aim of this study was to estimate the prevalence of cardiovascular risk factors among children and adolescents during the covid-19 pandemic based on the life's essential 8 domains. | pediatric obesity | eng | 2024 | Nov | Núñez-Cortés Rodrigo, López-Bueno Rubén, Torres-Castro Rodrigo, Calatayud Joaquín, Del Pozo Cruz Borja | department of physical therapy, faculty of medicine, university of chile, santiago, chile., department of physical medicine and nursing, university of zaragoza, zaragoza, spain., department of physical therapy, faculty of medicine, university of chile, santiago, chile., exercise intervention for health research group (exinh-rg), department of physiotherapy, university of valencia, valencia, spain., department of sports sciences, faculty of medicine, health, and sports, universidad europea de madrid, villaviciosa de odón, madrid, spain. | pediatric obesity | pediatr obes | 2047-6310 | 2047-6302 | 2.7 | 3.3 | PEDIATRICS|Q1|38/186 | faculty of medicine, university of chile, university of zaragoza, faculty of medicine, university of chile, university of valencia, faculty of medicine, universidad europea de madrid | Unknown | unknown | |||
| 81 | 80 | association of daily physical activity and bone microarchitecture in young adults with type 1 diabetes - a pilot exploratory study. | physical activity (pa) is an important determinant of skeletal health. in young adults with type 1 diabetes (t1d) fracture risk is increased, yet few studies have examined the pa and bone health relationship. therefore, this pilot cross-sectional study characterized pa levels and their association with bone parameters measured by high resolution peripheral quantitative computed tomography (hr-pqct) in young adults with t1d. | bone reports | eng | 2024 | Dec | West Sarah L, Furman Michelle, Moineddin Rahim, Sochett Etienne | department of kinesiology, trent university, peterborough, on, canada., department of pediatrics, division of endocrinology, the hospital for sick children, university of toronto, toronto, ontario, canada., department of family and community medicine, faculty of medicine, university of toronto, toronto, on, canada., department of pediatrics, division of endocrinology, the hospital for sick children, university of toronto, toronto, ontario, canada. | bone reports | bone rep | 2352-1872 | 2352-1872 | 2.1 | ENDOCRINOLOGY & METABOLISM|Q3|129/186 | trent university, division of endocrinology, the hospital for sick children, university of toronto, department of family and community medicine, faculty of medicine, university of toronto, department of pediatrics, division of endocrinology, the hospital for sick children, university of toronto | pilot cross-sectional study | trent university | ||||
| 82 | 81 | elevated remnant cholesterol and the risk of prevalent major depressive disorder: a nationwide population-based study. | remnant cholesterol (rc) has received increasing attention due to its association with a variety of diseases. however, comprehensive population-based studies elucidating the relationship between rc and major depressive disorder (mdd) are limited. the current study aimed to determine the association between rc and mdd in us adults. | frontiers in psychiatry | eng | 2024 | No Data | Tao Shiyi, Yu Lintong, Li Jun, Wu Ji, Yang Deshuang, Huang Xuanchun, Xue Tiantian | department of cardiology, guang'anmen hospital, china academy of chinese medical sciences, beijing, china., graduate school, beijing university of chinese medicine, beijing, china., department of cardiology, guang'anmen hospital, china academy of chinese medical sciences, beijing, china., department of cardiology, guang'anmen hospital, china academy of chinese medical sciences, beijing, china., department of integrative cardiology, china-japan friendship hospital, beijing, china., department of cardiology, guang'anmen hospital, china academy of chinese medical sciences, beijing, china., department of cardiology, guang'anmen hospital, china academy of chinese medical sciences, beijing, china. | frontiers in psychiatry | front psychiatry | 1664-0640 | 1664-0640 | 3.2 | 3.9 | PSYCHIATRY|Q2|88/276 | guang'anmen hospital, china academy of chinese medical sciences, beijing university of chinese medicine, guang'anmen hospital, china academy of chinese medical sciences, guang'anmen hospital, china academy of chinese medical sciences, guang'anmen hospital, china academy of chinese medical sciences, guang'anmen hospital, china academy of chinese medical sciences | comprehensive population-based studies | china academy | |||
| 83 | 82 | impact of co-administration of apricot kernels and caffeine on adult male diabetic albino rats. | the purpose of this study is to evaluate the impacts of apricot kernels and caffeine on blood glucose, lipid profile, insulin secretion, and antioxidant effect in diabetic rats. forty adult male albino rats were divided into five groups: normal control, diabetic control, diabetic rats treated with apricot kernels, diabetic rats treated with caffeine, and diabetic rats treated with apricot kernels plus caffeine. fasting samples were collected at the end of the study for analysis, and pieces of liver and pancreatic tissues were removed for histological analysis. there was a significant decrease in blood glucose, glycated hemoglobin, body weight, total cholesterol, triglyceride, and low-density lipoprotein cholesterol (ldl-c) levels and a significant increase in insulin and high-density lipoprotein cholesterol (hdl-c) levels in the kernel and caffeine-treated groups. however, there was little histological alteration in the liver or pancreas, and no significant differences were observed in the histological findings between groups. overall, it can be concluded that apricot kernel and caffeine had a positive effect in decreasing blood glucose and harmful lipid profile and that caffeine had a synergistic effect on the apricot kernel. | frontiers in physiology | eng | 2024 | No Data | Nour El-Deen Ahmed El Sayed, Taha Ahmad Mohamad, Elsayed Almoatazbellah, Ali Ahmed Noaman, Taha Reda Samir | department of basic medical and dental sciences, faculty of dentistry, zarqa university, zarqa, jordan., department of basic medical and dental sciences, faculty of dentistry, zarqa university, zarqa, jordan., department of basic medical and dental sciences, faculty of dentistry, zarqa university, zarqa, jordan., department of basic medical and dental sciences, faculty of dentistry, zarqa university, zarqa, jordan., department of basic medical and dental sciences, faculty of dentistry, zarqa university, zarqa, jordan. | frontiers in physiology | front physiol | 1664-042X | 3.2 | 4.0 | PHYSIOLOGY|Q2|24/85 | department of basic medical and dental sciences, faculty of dentistry, zarqa university, department of basic medical and dental sciences, faculty of dentistry, zarqa university, department of basic medical and dental sciences, faculty of dentistry, zarqa university, department of basic medical and dental sciences, faculty of dentistry, zarqa university, department of basic medical and dental sciences, faculty of dentistry, zarqa university | normal control | zarqa university | zarqa university | Reporter | n/a | |
| 84 | 83 | the role of anti-aging approaches in managing hypogonadism in sedentary older males. | with thirty percent of the world's population not getting enough exercise, worldwide, physical inactivity ranks as one of the most common causes of premature mortality. rapid drops in physical activity, decreased mobility, and early morbidity are aging characteristics. as the population over 80 continues to rise, aging raises the danger of age-related illnesses and changes in hormone release. | frontiers in aging | eng | 2024 | No Data | Abdel-Sater Khaled A | faculty of dentistry, mutah university, karak, jordan. | frontiers in aging | front aging-lausanne | 2673-6217 | 3.3 | 3.4 | GERIATRICS & GERONTOLOGY|Q2|35/74 | faculty of dentistry, mutah university | Unknown | mutah university | mutah university | 1201–1500 | 11.5 | |
| 85 | 84 | ocular immune-related diseases: molecular mechanisms and therapy. | ocular immune-related diseases, represent a spectrum of conditions driven by immune system dysregulation, include but not limit to uveitis, diabetic retinopathy, age-related macular degeneration, graves' ophthalmopathy, etc. the molecular and cellular mechanisms underlying these diseases are typically dysfunctioned immune responses targeting ocular tissues, resulting in inflammation and tissue damage. recent advances have further elucidated the pivotal role of different immune responses in the development, progression, as well as management of various ocular immune diseases. however, there is currently a relative lack of connection between the cellular mechanisms and treatments of several immune-related ocular diseases. in this review, we discuss recent findings related to the immunopathogenesis of above-mentioned diseases. in particular, we summarize the different types of immune cells, inflammatory mediators, and associated signaling pathways that are involved in the pathophysiology of above-mentioned ophthalmopathies. furthermore, we also discuss the future directions of utilizing anti-inflammatory regime in the management of these diseases. this will facilitate a better understanding of the pathogenesis of immune-related ocular diseases and provide new insights for future treatment approaches. | medcomm | eng | 2024 | Dec | Wang Yakun, Gao Shangze, Cao Fan, Yang Hui, Lei Fengyang, Hou Shengping | the first affiliated hospital of chongqing medical university chongqing china., beijing institute of ophthalmology beijing tongren eye center beijing tongren hospital, beijing ophthalmology & visual sciences key laboratory, capital medical university beijing china., beijing institute of ophthalmology beijing tongren eye center beijing tongren hospital, beijing ophthalmology & visual sciences key laboratory, capital medical university beijing china., beijing institute of ophthalmology beijing tongren eye center beijing tongren hospital, beijing ophthalmology & visual sciences key laboratory, capital medical university beijing china., beijing institute of ophthalmology beijing tongren eye center beijing tongren hospital, beijing ophthalmology & visual sciences key laboratory, capital medical university beijing china., beijing institute of ophthalmology beijing tongren eye center beijing tongren hospital, beijing ophthalmology & visual sciences key laboratory, capital medical university beijing china. | medcomm | medcomm | 2688-2663 | 10.7 | 9.7 | MEDICINE, RESEARCH & EXPERIMENTAL|Q1|11/189 | chongqing medical university, beijing institute of ophthalmology, capital medical university, beijing institute of ophthalmology, capital medical university, beijing institute of ophthalmology, capital medical university, beijing institute of ophthalmology, capital medical university, beijing institute of ophthalmology, capital medical university | Unknown | medical university | ||||
| 86 | 85 | combination of dmdd with nanoparticles effective against diabetic kidney disease in vitro. | 2-dodecyl-6-methoxy-2,5-diene-1,4-cyclohexanedione (dmdd), isolated from <i>averrhoa carambola l</i>. root, has demonstrated the potential to reduce blood sugar levels. however, dmdd has poor solubility and bioavailability. this study aimed to formulate dmdd-loaded nanoparticles (dmdd-nps) using chitosan crosslinked with sodium tripolyphosphate through the ionic crosslinking method and to investigate their effect on diabetic kidney disease (dkd) treatment by inhibiting the development of the epithelial-mesenchymal transition (emt). | international journal of nanomedicine | eng | 2024 | No Data | Huang Xiao-Man, Guo Yan-Xiang, Pang Qiu-Ling, Yan Xiao-Yi, Yan Hui, Li Jing-Yi, Tang Gan-Ling, Jiang Hui-Xian, Zhang Hong-Liang | the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china., the first affiliated hospital of guangxi medical university, nanning, guangxi, 530021, people's republic of china. | international journal of nanomedicine | int j nanomed | 1178-2013 | 1178-2013 | 6.6 | 7.5 | PHARMACOLOGY & PHARMACY|Q1|20/354 | guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china, guangxi medical university, people's republic of china | study | medical university | |||
| 87 | 86 | reversible cerebral vasoconstriction syndrome following blood transfusion in a patient with chronic anemia: a case report. | reversible cerebral vasoconstriction syndrome (rcvs) is a rare neurological disorder characterized by transient constriction and dilation of cerebral arteries, leading to severe headaches and neurological deficits. this case report describes a 41-year-old woman with chronic anemia, acute chronic kidney disease, type 2 diabetes mellitus, and rheumatoid arthritis who developed rcvs following transfusion of packed red blood cells (prbcs). she experienced sudden-onset seizures and a thunderclap headache 5 days post-transfusion. diagnostic imaging, including computed tomography (ct) and magnetic resonance imaging (mri), revealed the characteristic features of vasogenic edema. the patient was treated with blood pressure control and symptomatic relief for pain, resulting in gradual improvement. this case highlights the importance of recognizing rcvs as a potential complication of blood transfusions, particularly in patients with significant comorbidities. understanding the possible mechanisms, including rapid hemoglobin correction, and the effects of residual plasma and storage lesions in transfused blood, is essential to prevent and manage this rare but serious condition. | clinical case reports | eng | 2024 | Dec | Verma Amogh, Sharma Govind, Singh Ajeet, Gupta Harshit, Singh Deependra Pratap, Gaidhane Abhay M, Khatib Mahalaqua Nazli, Bushi Ganesh, Sah Sanjit, Ndabashinze Rodrigue | department of internal medicine rama medical college hospital and research center hapur uttar pradesh india., department of radiology rama medical college hospital and research center hapur uttar pradesh india., department of internal medicine dow university of health sciences karachi pakistan., department of internal medicine all india institute of medical sciences (aiims) rishikesh rishikesh india., department of biotechnology graphic era hill university dehradun india., school of epidemiology and public health, jawaharlal nehru medical college and global health academy datta meghe institute of higher education wardha india., division of evidence synthesis, global consortium of public health and research datta meghe institute of higher education wardha india., center for global health research saveetha medical college and hospital, saveetha institute of medical and technical sciences, saveetha university chennai india., dr. d. y. patil medical college, hospital and research centre, dr. d. y. patil vidyapeeth pune maharashtra india., university of burundi bujumbura burundi. | clinical case reports | clin case rep | 2050-0904 | 2050-0904 | 0.6 | 0.6 | MEDICINE, GENERAL & INTERNAL|Q3|219/325 | rama medical college, rama medical college, dow university of health sciences karachi pakistan, jawaharlal nehru medical college, global health academy, division of evidence synthesis, saveetha medical college, saveetha institute of medical and technical sciences, saveetha university chennai, dr. d. y. patil medical college, university of burundi bujumbura burundi | Unknown | medical college | |||
| 88 | 87 | labial fusion in a postmenopausal woman presenting with urinary incontinence. | genitourinary syndrome of menopause refers to the collection of signs and symptoms associated with decrease in estrogen and other sex steroids involving changes in labia majora/minora, clitoris, vestibule/introitus, vagina, urethra, and bladder. this term was coined in 2014 to reduce the stigma associated with genital symptoms after menopause. our patient is a 65-year-old woman, menopausal for the past 15 years, who presented with dribbling of urine for 1 month. on examination, she was diagnosed with complete labial fusion. diabetes was incidentally detected and antidiabetic treatment was started. considering dense labial adhesion, the patient underwent surgical separation of labia under anesthesia. postoperatively, she was put on topical estrogen therapy and was advised to maintain proper hygiene. she was followed up regularly for a month to prevent refusion. | journal of mid-life health | eng | 2024 | No Data | Arpit A Vachhani, Nilam K Patel, Smitul A Vachhani, Anita J Shah | consultant gynaecologist and menopause practitioner, atmiya maternity and nursing home, surat, gujarat, india., consultant gynaecologist and menopause practitioner, harsh hospital, surat, gujarat, india., bj medical college, ahmedabad, gujarat, india., consultant gynaecologist and menopause practitioner, hope women's hospital, surat, gujarat, india. | journal of mid-life health | j mid-life health | 0976-7800 | 0976-7819 | 1.2 | OBSTETRICS & GYNECOLOGY|Q3|98/136 | atmiya maternity and nursing home, harsh hospital, bj medical college, hope women's hospital | Unknown | medical college | ||||
| 89 | 88 | influence of clinical, angiographic, and developmental characteristics and covid-19 severity and vaccination status on young patients with acute myocardial infarction. | atherosclerosis is the most common cause of ischemic cardiovascular disease (cvd). however, approximately 20%-40% of cases of acute myocardial infarction (ami) in patients aged <50 years can be attributed to genetic factors, and coronavirus disease 2019 (covid-19) is a risk factor for blood clots and ami. we aimed to describe the clinical, angiographic, and developmental characteristics and covid-19 severity and vaccination status in patients aged ≤45 years with ami. | journal of mid-life health | eng | 2024 | No Data | Vityala Yethindra, Palagudi Mahesh, Para Sneha, Meduri Krishna Chaitanya, Duvvuri Sai Praneeth, Manne Lakshmi Narasimha Sandeep, Garg Ruchika, Damineni Ujwala, Kanteti Krishna Priya | honorary international faculty, aj institute of medical sciences and research centre, mangalore, karnataka, india., department of general medicine, p. e. s. institute of medical sciences and research, kuppam, andhra pradesh, india., department of general medicine, maheshwara medical college and hospital, hyderabad, telangana, india., department of general medicine, maheshwara medical college and hospital, hyderabad, telangana, india., department of general medicine, maheshwara medical college and hospital, hyderabad, telangana, india., department of general medicine, srm medical college hospital and research centre, kattankulathur, tamil nadu, india., department of obstetrics and gynecology, sn medical college, agra, uttar pradesh, india., department of general medicine, maheshwara medical college and hospital, hyderabad, telangana, india., department of general medicine, gandhi medical college and hospital, secunderabad, telangana, india. | journal of mid-life health | j mid-life health | 0976-7800 | 0976-7819 | 1.2 | OBSTETRICS & GYNECOLOGY|Q3|98/136 | aj institute of medical sciences and research centre, department of general medicine, p. e. s. institute of medical sciences and research, department of general medicine, maheshwara medical college and hospital, department of general medicine, maheshwara medical college and hospital, department of general medicine, maheshwara medical college and hospital, department of general medicine, srm medical college hospital and research centre, sn medical college, department of general medicine, maheshwara medical college and hospital, department of general medicine, gandhi medical college and hospital | Unknown | aj institute | ||||
| 90 | 89 | unleashing the potential of extracellular vesicles for ulcerative colitis and crohn's disease therapy. | image 1. | bioactive materials | eng | 2025 | Mar | Njoku George Chigozie, Forkan Cathal Patrick, Soltysik Fumie Mitani, Nejsum Peter Lindberg, Pociot Flemming, Yarani Reza | translational type 1 diabetes research, department of clinical and translational research, steno diabetes center copenhagen, herlev, denmark., translational type 1 diabetes research, department of clinical and translational research, steno diabetes center copenhagen, herlev, denmark., translational type 1 diabetes research, department of clinical and translational research, steno diabetes center copenhagen, herlev, denmark., department of clinical medicine, aarhus university, aarhus, denmark., translational type 1 diabetes research, department of clinical and translational research, steno diabetes center copenhagen, herlev, denmark., translational type 1 diabetes research, department of clinical and translational research, steno diabetes center copenhagen, herlev, denmark. | bioactive materials | bioact mater | 2452-199X | 18.0 | 18.2 | MATERIALS SCIENCE, BIOMATERIALS|Q1|1/53 | department of clinical and translational research, steno diabetes center copenhagen, department of clinical and translational research, steno diabetes center copenhagen, department of clinical and translational research, steno diabetes center copenhagen, department of clinical medicine, aarhus university, department of clinical and translational research, steno diabetes center copenhagen, department of clinical and translational research, steno diabetes center copenhagen | Unknown | aarhus university | aarhus university | 109 | 59.0 | |
| 91 | 90 | global research dynamics in the mediterranean diet and diabetes mellitus: a bibliometric study from 2014 to 2024. | the mediterranean diet (meddiet) has been found to have benefits for diabetes mellitus (dm), but a bibliometric analysis of its association with dm has yet to be conducted. this paper aims to explore the current status and research hotspots on the connection between the mediterranean diet and dm from 2014 to 2024, providing a reference for future studies. | frontiers in nutrition | eng | 2024 | No Data | Yan Yuanyuan, Li Zonghuai, Lian Yuanchu, Liu Pingping, Zhang Bo, Chen Juan | department of pharmacy, sanya central hospital (the third people's hospital of hainan province), hainan, china., scientific research center, guilin medical university, guilin, china., scientific research center, guilin medical university, guilin, china., department of pharmacy, sanya central hospital (the third people's hospital of hainan province), hainan, china., scientific research center, guilin medical university, guilin, china., department of pharmacy, sanya central hospital (the third people's hospital of hainan province), hainan, china. | frontiers in nutrition | front nutr | 2296-861X | 2296-861X | 4.0 | 4.4 | NUTRITION & DIETETICS|Q2|31/114 | department of pharmacy, sanya central hospital, scientific research center, guilin medical university, scientific research center, guilin medical university, department of pharmacy, sanya central hospital, scientific research center, guilin medical university, department of pharmacy, sanya central hospital | Unknown | medical university | |||
| 92 | 91 | harnessing the nutraceutical and therapeutic potential of <i>allium</i> spp.: current insights and future directions. | apart from the culinary usage, alliums are known for their therapeutic potential since antiquity. alliums contain diverse bioactive compounds such as, sulfur-containing compounds (allicin, diallyl sulfides), flavonoids, and saponins. these compounds have demonstrated a wide range of pharmacological actions, including antioxidant, anticancer, anti-inflammatory, antimicrobial, neuroprotective, cardioprotective activities and treatment of metabolic disorders such as diabetes and hyperlipidemia. despite encouraging preclinical results, translating these findings into clinical practice remains difficult, necessitating more rigorous human trials and molecular research. one of the major constrain in enhancing the therapeutic efficacy of these bioactive compound is to develop large-scale extraction techniques besides improving their stability, solubility, and bioavailability. the current scenario urges to focus research on optimizing the bioavailability of these compounds, evaluate their synergistic effects with existing therapies, as well as their long-term safety. this perspective article provides a comprehensive overview of the therapeutic potential of <i>allium</i> spp. and suggests the key avenues for future research aiming at realising their full clinical potential. | frontiers in nutrition | eng | 2024 | No Data | Gorrepati Kalyani, Krishna Ram, Singh Saurabh, Shirsat Dhananjay V, Soumia P S, Mahajan Vijay | icar-directorate of onion and garlic research, rajgurunagar, pune, india., icar-indian institute of vegetable research, varanasi, india., institute of environment and sustainable development, banaras hindu university, varanasi, india., icar-directorate of onion and garlic research, rajgurunagar, pune, india., icar-directorate of onion and garlic research, rajgurunagar, pune, india., icar-directorate of onion and garlic research, rajgurunagar, pune, india. | frontiers in nutrition | front nutr | 2296-861X | 2296-861X | 4.0 | 4.4 | NUTRITION & DIETETICS|Q2|31/114 | icar-directorate of onion and garlic research, icar-indian institute of vegetable research, institute of environment and sustainable development, banaras hindu university, icar-directorate of onion and garlic research, icar-directorate of onion and garlic research, icar-directorate of onion and garlic research | human trials | indian institute | |||
| 93 | 92 | non-diabetic elderly populations: siri as a risk factor and piv as a protective factor against bone abnormalities. | the prevalence of osteoporosis and its resultant healthcare challenges are escalating, posing significant burdens on public health systems. studies have introduced immunoinflammatory indices, which are recognized for effectively reflecting the systemic immunoinflammatory status. despite their potential, the exploration of these indices in the context of osteoporosis remains limited. the study sought to explore the relationship between immune inflammation-related indices and osteoporosis in non-diabetic elderly populations. | frontiers in endocrinology | eng | 2024 | No Data | Yan Manli, Gong Ping, Li Xiang, Huang Haoyue, Wei Hua | second clinical medical college, guangzhou university of traditional chinese medicine, guangzhou, china., second clinical medical college, guangzhou university of traditional chinese medicine, guangzhou, china., department of orthopedic, guangdong provincial hospital of chinese medicine, guangzhou, china., department of endocrinology, guangdong provincial hospital of chinese medicine, guangzhou, china., department of endocrinology, guangdong provincial hospital of chinese medicine, guangzhou, china. | frontiers in endocrinology | front endocrinol | 1664-2392 | 1664-2392 | 3.9 | 4.9 | ENDOCRINOLOGY & METABOLISM|Q2|51/186 | second clinical medical college, guangzhou university of traditional chinese medicine, second clinical medical college, guangzhou university of traditional chinese medicine, guangdong provincial hospital of chinese medicine, guangdong provincial hospital of chinese medicine, guangdong provincial hospital of chinese medicine | studies | medical college | |||
| 94 | 93 | predicting hypoglycemia in elderly inpatients with type 2 diabetes: the adochbiu model. | hypoglycemic episodes cause varying degrees of damage in the functional system of elderly inpatients with type 2 diabetes mellitus (t2dm). the purpose of the study is to construct a nomogram prediction model for the risk of hypoglycemia in elderly inpatients with t2dm and to evaluate the predictive performance of the model. | frontiers in endocrinology | eng | 2024 | No Data | Zhang Rui-Ting, Liu Yu, Sun Chao, Wu Quan-Ying, Guo Hong, Wang Gong-Ming, Lin Ke-Ke, Wang Jing, Bai Xiao-Yan | school of nursing, beijing university of chinese medicine, beijing, china., school of nursing, beijing university of chinese medicine, beijing, china., nursing department, beijing hospital, beijing, china., nursing department, beijing hospital, beijing, china., school of nursing, beijing university of chinese medicine, beijing, china., nursing department, beijing hospital, beijing, china., school of nursing, beijing university of chinese medicine, beijing, china., school of nursing, beijing university of chinese medicine, beijing, china., school of nursing, beijing university of chinese medicine, beijing, china. | frontiers in endocrinology | front endocrinol | 1664-2392 | 1664-2392 | 3.9 | 4.9 | ENDOCRINOLOGY & METABOLISM|Q2|51/186 | school of nursing, beijing university of chinese medicine, school of nursing, beijing university of chinese medicine, school of nursing, beijing university of chinese medicine, school of nursing, beijing university of chinese medicine, school of nursing, beijing university of chinese medicine, school of nursing, beijing university of chinese medicine | Unknown | beijing university | |||
| 95 | 94 | trajectories of cognitive function and frailty in older adults in china: a longitudinal study. | cognitive impairment and frailty are common issues in older adults. understanding the co-development trajectories of these conditions can provide valuable sights for early detection and intervention in high-risk individuals. | frontiers in aging neuroscience | eng | 2024 | No Data | Ji Xiaoyi, Wu Yue, Gu Zijie, Zhong Zhujun, Wang Kerui, Ye Suni, Wan Yang, Qiu Peiyuan | west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china., west china school of public health and west china fourth hospital, sichuan university, chengdu, china. | frontiers in aging neuroscience | front aging neurosci | 1663-4365 | 1663-4365 | 4.1 | 4.6 | NEUROSCIENCES|Q2|80/310 | west china school of public health, sichuan university, west china school of public health, sichuan university, west china school of public health, sichuan university, west china school of public health, sichuan university, west china school of public health, sichuan university, west china school of public health, sichuan university, west china school of public health, sichuan university, west china school of public health, sichuan university | Unknown | china school | |||
| 96 | 95 | ctx-1 and tracp-5b as biomarkers for osteoporosis risk in type 2 diabetes mellitus: a cross-sectional study. | type 2 diabetes mellitus (t2dm) demonstrates a higher risk of fractures compared to the healthy population. therefore, the aim of our study is to assess the risk of osteoporosis in t2dm patients. | journal of diabetes and metabolic disorders | eng | 2024 | Dec | Roy Madhura, Majid Haya, Khan Parvej, Sharma Nikhil, Kohli Sunil, Islam Sajad Ul, Vohora Divya | department of translational and clinical research, school of chemical and life sciences, jamia hamdard, new delhi, 110062 india., department of translational and clinical research, school of chemical and life sciences, jamia hamdard, new delhi, 110062 india., department of translational and clinical research, school of chemical and life sciences, jamia hamdard, new delhi, 110062 india., department of pharmacy practice, school of pharmaceutical education and research, jamia hamdard, new delhi, 110062 india., department of medicine, hamdard institute of medical science and research, new delhi, 110062 india., department of medicine, hamdard institute of medical science and research, new delhi, 110062 india., department of pharmacology, school of pharmaceutical education and research, jamia hamdard, new delhi, 110062 india., No Affiliation | journal of diabetes and metabolic disorders | j diabetes metab dis | 2251-6581 | 1.8 | 2.4 | ENDOCRINOLOGY & METABOLISM|Q4|143/186 | department of translational and clinical research, school of chemical and life sciences, jamia hamdard, department of translational and clinical research, school of chemical and life sciences, jamia hamdard, department of translational and clinical research, school of chemical and life sciences, jamia hamdard, department of pharmacy practice, school of pharmaceutical education and research, jamia hamdard, department of medicine, hamdard institute of medical science and research, department of medicine, hamdard institute of medical science and research, department of pharmacology, school of pharmaceutical education and research, jamia hamdard | Unknown | hamdard institute | ||||
| 97 | 96 | dynapenia-abdominal obesity and mortality risk, is independent effect obscured by age and frailty?:birjand longitudinal aging study (blas). | abdominal obesity and low muscle strength, known separately as risk factors for mortality, might have a synergistic effect when they co-occur. dynapenic abdominal obesity (dao) is a condition defined by the presence of both. however, dao's independent and combined impact on mortality remains under investigation. | journal of diabetes and metabolic disorders | eng | 2024 | Dec | Rahimi Farahani Marjan, Sharifi Farshad, Payab Moloud, Shadman Zhaleh, Fakhrzadeh Hossein, Moodi Mitra, Khorashadizadeh Masoumeh, Ebrahimpur Mahbube, Taheri Maryam, Ebrahimi Pouya, Larijani Bagher | non-communicable disease research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran., elderly health research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran., non-communicable disease research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran., elderly health research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran., elderly health research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran., social determinants of health research center, birjand university of medical sciences, birjand, iran., social determinants of health research center, birjand university of medical sciences, birjand, iran., elderly health research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran., faculty of medicine, cardiology research center, hamadan university of medical sciences, tehran, iran., tehran heart center, cardiovascular disease research institute, tehran university of medical sciences, tehran, iran., endocrinology and metabolism research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, iran. | journal of diabetes and metabolic disorders | j diabetes metab dis | 2251-6581 | 1.8 | 2.4 | ENDOCRINOLOGY & METABOLISM|Q4|143/186 | tehran university of medical sciences, tehran university of medical sciences, tehran university of medical sciences, tehran university of medical sciences, tehran university of medical sciences, birjand university of medical sciences, birjand university of medical sciences, tehran university of medical sciences, faculty of medicine, hamadan university of medical sciences, tehran university of medical sciences, tehran university of medical sciences | Unknown | tehran university | ||||
| 98 | 97 | a policy package for socio-cultural factors of promoting healthy diet in iran. | non-communicable diseases (ncds) cause 74% of global deaths annually, for which poor diet is the leading risk factor. diet improvement could prevent 20% of global deaths. this paper presents a policy package for socio-cultural factors, strategies, and policies to promote a healthy diet in iran. | journal of diabetes and metabolic disorders | eng | 2024 | Dec | Amerzadeh Mohammad, Takian Amirhossein, Pouraram Hamed, Sari Ali Akbari, Ostovar Afshin | social determinants of health research center, research institute for prevention of non-communicable diseases, qazvin university of medical sciences, qazvin, iran., department of health management, policy & economics, school of public health, tehran university of medical sciences (tums), tehran, iran., department of community nutrition, school of nutritional sciences and dietetics, tehran university of medical sciences (tums), tehran, iran., department of health management, policy & economics, school of public health, tehran university of medical sciences (tums), tehran, iran., endocrinology & metabolism research institute, tehran university of medical sciences (tums), tehran, iran. | journal of diabetes and metabolic disorders | j diabetes metab dis | 2251-6581 | 1.8 | 2.4 | ENDOCRINOLOGY & METABOLISM|Q4|143/186 | qazvin university of medical sciences, department of health management, policy & economics, school of public health, tehran university of medical sciences, tehran university of medical sciences (tums), department of health management, policy & economics, school of public health, tehran university of medical sciences (tums), endocrinology & metabolism research institute, tehran university of medical sciences (tums) | Unknown | qazvin university | ||||
| 99 | 98 | assessing the efficacy of topical formulations in diabetic neuropathy: a narrative review. | we conducted a review of topical medications available for alleviation of diabetic neuropathic pain (dnp) and compared their efficacy with oral medications for pain relief. we also explored the feasibility of compounding topical medications. | journal of diabetes and metabolic disorders | eng | 2024 | Dec | Elbeddini Ali, Tanvir Azasma, Yilmaz Orhan, Rahman Yusra, Mongon Renata | family medicine department, university of ottawa, school of medicine, 600 peter morand crescent suite 201, ottawa, on k1g 5z3 canada., college of medicine, university of saskatchewan, 107 wiggins rd, saskatoon, sk s7n 5e5 canada., college of medicine, university of saskatchewan, 107 wiggins rd, saskatoon, sk s7n 5e5 canada., faculty of health sciences, mcmaster university, 1280 main street west, hamilton, on l8s 4l8 canada., anesthesiology department, state university of campinas, campinas, brazil. | journal of diabetes and metabolic disorders | j diabetes metab dis | 2251-6581 | 1.8 | 2.4 | ENDOCRINOLOGY & METABOLISM|Q4|143/186 | university of ottawa, school of medicine, college of medicine, university of saskatchewan, college of medicine, university of saskatchewan, faculty of health sciences, mcmaster university, state university of campinas | Unknown | mcmaster university | mcmaster university | 103 | 51.3 | |
| 100 | 99 | advanced 3d-dxa insights into bone density changes in hyperparathyroidism. | primary hyperparathyroidism (phpt) is a disorder marked by chronic parathyroid hormone hypersecretion, which affects bone turnover and remodelling processes. with a loss of bone density and an increase in bone porosity, the cortical compartment is most severely impacted. the study's goal is to assess phpt's effects on the volumetric bone mineral density (vbmd) of the femur's trabecular compartment as well as the vbmd and thickness of the cortical bone. | journal of diabetes and metabolic disorders | eng | 2024 | Dec | Guerra Francesco Saverio, Palladino Nicola, Winzenrieth Renaud, Guglielmi Giuseppe | department of clinical and experimental medicine, foggia university school of medicine, foggia, italy., department of clinical and experimental medicine, foggia university school of medicine, foggia, italy., 3d-sharper medical, barcelona, spain., department of clinical and experimental medicine, foggia university school of medicine, foggia, italy. | journal of diabetes and metabolic disorders | j diabetes metab dis | 2251-6581 | 1.8 | 2.4 | ENDOCRINOLOGY & METABOLISM|Q4|143/186 | department of clinical and experimental medicine, foggia university school of medicine, department of clinical and experimental medicine, foggia university school of medicine, 3d-sharper medical, department of clinical and experimental medicine, foggia university school of medicine | study | foggia university |