--- a
+++ b/processing/MACCROBAT/27793101.ann
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+T1	Age 2 13	70-year-old
+T2	Sex 14 18	male
+T3	Clinical_event 23 31	admitted
+E1	Clinical_event:T3 
+T4	Disease_disorder 105 113	aneurysm
+E2	Disease_disorder:T4 
+T5	Biological_structure 88 104	abdominal aortic
+R1	MODIFY Arg1:T5 Arg2:E2	
+T6	Diagnostic_procedure 66 84	cardiac evaluation
+E3	Diagnostic_procedure:T6 
+T7	Date 240 254	4 years before
+E4	Date:T7 
+T8	Therapeutic_procedure 141 172	coronary artery bypass grafting
+E5	Therapeutic_procedure:T8 
+T9	Therapeutic_procedure 174 178	CABG
+E6	Therapeutic_procedure:T9 
+R2	IDENTICAL Arg1:E6 Arg2:E5	
+T10	Sign_symptom 191 199	stenosis
+E7	Sign_symptom:T10 
+T11	Severity 184 190	severe
+R3	MODIFY Arg1:T11 Arg2:E7	
+T12	Biological_structure 207 232	left main coronary artery
+T13	Biological_structure 234 238	LMCA
+R4	IDENTICAL Arg1:T13 Arg2:T12	
+R5	MODIFY Arg1:T12 Arg2:E7	
+T14	Biological_structure 279 309	right internal thoracic artery
+T15	Biological_structure 311 315	RITA
+R6	IDENTICAL Arg1:T15 Arg2:T14	
+T16	Biological_structure 324 355	left anterior descending artery
+T17	Biological_structure 357 360	LAD
+R7	MODIFY Arg1:T17 Arg2:T16	
+T18	Therapeutic_procedure 366 386	saphenous vein graft
+E8	Therapeutic_procedure:T18 
+T19	Therapeutic_procedure 388 391	SVG
+E9	Therapeutic_procedure:T19 
+R8	IDENTICAL Arg1:E9 Arg2:E8	
+T20	Biological_structure 400 422	left circumflex artery
+T21	Biological_structure 424 427	LCX
+R9	IDENTICAL Arg1:T21 Arg2:T20	
+T22	Outcome 3428 3432	died
+E10	Outcome:T22 
+T23	Therapeutic_procedure 3464 3488	external cardiac massage
+E11	Therapeutic_procedure:T23 
+T24	Disease_disorder 3438 3452	aortic rupture
+E12	Disease_disorder:T24 
+R10	CAUSE Arg1:E11 Arg2:E12	
+R11	CAUSE Arg1:E12 Arg2:E10	
+T25	Detailed_description 52 65	perioperative
+R12	MODIFY Arg1:T25 Arg2:E3	
+T26	Disease_disorder 478 486	aneurysm
+E13	Disease_disorder:T26 
+A1	TREND E13 INC
+T27	Therapeutic_procedure 503 510	surgery
+E14	Therapeutic_procedure:T27 
+T28	Biological_structure 461 477	abdominal aortic
+R13	MODIFY Arg1:T28 Arg2:E13	
+T31	Diagnostic_procedure 540 549	angiogram
+E15	Diagnostic_procedure:T31 
+T32	Biological_structure 526 539	Left coronary
+R16	MODIFY Arg1:T32 Arg2:E15	
+T29	Sign_symptom 562 570	stenosis
+E16	Sign_symptom:T29 
+T30	Lab_value 557 561	90 %
+E17	Lab_value:T30 
+R14	MODIFY Arg1:E17 Arg2:E16	
+T33	Biological_structure 578 582	LMCA
+R15	MODIFY Arg1:T33 Arg2:E16	
+T34	Sign_symptom 593 602	occlusion
+E18	Sign_symptom:T34 
+T35	Severity 587 592	total
+R17	MODIFY Arg1:T35 Arg2:E18	
+T36	Coreference 611 617	grafts
+E19	Coreference:T36 
+R18	IDENTICAL Arg1:E19 Arg2:E8	
+T37	Detailed_description 606 610	both
+R19	MODIFY Arg1:T37 Arg2:E19	
+T38	Biological_structure 641 645	LMCA
+T39	Therapeutic_procedure 3399 3414	surgical repair
+E20	Therapeutic_procedure:T39 
+T40	Therapeutic_procedure 619 622	PCI
+E21	Therapeutic_procedure:T40 
+#1	AnnotatorNotes E21	Percutaneous coronary intervention
+T41	Sign_symptom 646 654	stenosis
+E22	Sign_symptom:T41 
+R20	MODIFY Arg1:T38 Arg2:E22	
+T42	Therapeutic_procedure 671 677	sheath
+E23	Therapeutic_procedure:T42 
+T43	Detailed_description 666 670	7-Fr
+R21	MODIFY Arg1:T43 Arg2:E23	
+T44	Biological_structure 700 720	right femoral artery
+R22	MODIFY Arg1:T44 Arg2:E23	
+T45	Therapeutic_procedure 741 749	catheter
+E24	Therapeutic_procedure:T45 
+T46	Detailed_description 733 740	guiding
+T47	Detailed_description 728 732	CLS4
+R23	MODIFY Arg1:T46 Arg2:E24	
+R24	MODIFY Arg1:T47 Arg2:E24	
+T48	Biological_structure 808 828	left coronary artery
+T49	Biological_structure 830 833	LCA
+T50	Biological_structure 835 841	ostium
+R25	MODIFY Arg1:T50 Arg2:T48	
+R26	IDENTICAL Arg1:T49 Arg2:T48	
+R27	MODIFY Arg1:T48 Arg2:E24	
+T51	Therapeutic_procedure 845 854	guidewire
+E25	Therapeutic_procedure:T51 
+T52	Biological_structure 917 927	distal LAD
+R28	MODIFY Arg1:T52 Arg2:E25	
+T53	Therapeutic_procedure 941 950	guidewire
+E26	Therapeutic_procedure:T53 
+T54	Biological_structure 1041 1051	distal LCX
+R29	MODIFY Arg1:T54 Arg2:E26	
+T55	Diagnostic_procedure 1053 1077	Intravascular ultrasound
+E27	Diagnostic_procedure:T55 
+T56	Diagnostic_procedure 1079 1083	IVUS
+E28	Diagnostic_procedure:T56 
+R30	IDENTICAL Arg1:E28 Arg2:E27	
+T57	Sign_symptom 1164 1177	calcification
+E29	Sign_symptom:T57 
+T58	Severity 1142 1147	heavy
+R31	MODIFY Arg1:T58 Arg2:E29	
+T59	Sign_symptom 1190 1196	lesion
+E30	Sign_symptom:T59 
+R32	MODIFY Arg1:E29 Arg2:E30	
+T60	Biological_structure 1185 1189	LMCA
+R33	MODIFY Arg1:T60 Arg2:E30	
+T61	Detailed_description 1148 1163	circumferential
+R34	MODIFY Arg1:T61 Arg2:E29	
+T62	Therapeutic_procedure 1243 1251	catheter
+E31	Therapeutic_procedure:T62 
+T63	Detailed_description 1235 1242	balloon
+T64	Detailed_description 1218 1234	Quantum Maverick
+T65	Detailed_description 1206 1217	4.0 × 15-mm
+R35	MODIFY Arg1:T63 Arg2:E31	
+R36	MODIFY Arg1:T64 Arg2:E31	
+R37	MODIFY Arg1:T65 Arg2:E31	
+T66	Detailed_description 1086 1100	Intra-focus WR
+T67	Detailed_description 952 970	Hi-Torque Pilot 50
+T68	Detailed_description 856 865	SION Blue
+R38	MODIFY Arg1:T68 Arg2:E25	
+R39	MODIFY Arg1:T67 Arg2:E26	
+R40	MODIFY Arg1:T66 Arg2:E28	
+T69	Sign_symptom 1292 1298	lesion
+E32	Sign_symptom:T69 
+T70	Biological_structure 1300 1303	LCA
+T71	Diagnostic_procedure 1304 1313	angiogram
+E33	Diagnostic_procedure:T71 
+T72	Sign_symptom 1331 1341	dissection
+E34	Sign_symptom:T72 
+T73	Severity 1325 1330	large
+R41	MODIFY Arg1:T73 Arg2:E34	
+T74	Therapeutic_procedure 1383 1388	stent
+E35	Therapeutic_procedure:T74 
+T75	Detailed_description 1365 1382	Multi-Link Vision
+T76	Detailed_description 1353 1364	4.0 × 28-mm
+R42	MODIFY Arg1:T75 Arg2:E35	
+R43	MODIFY Arg1:T76 Arg2:E35	
+T77	Diagnostic_procedure 2434 2445	vital signs
+E36	Diagnostic_procedure:T77 
+T78	Sign_symptom 2456 2473	cardiogenic shock
+E37	Sign_symptom:T78 
+T79	Clinical_event 2326 2334	admitted
+E38	Clinical_event:T79 
+T80	Nonbiological_location 2342 2356	emergency room
+R44	MODIFY Arg1:T80 Arg2:E38	
+T81	Sign_symptom 2378 2382	pain
+E39	Sign_symptom:T81 
+T82	Biological_structure 2372 2377	chest
+R45	MODIFY Arg1:T82 Arg2:E39	
+T83	Sign_symptom 2387 2395	dyspnoea
+E40	Sign_symptom:T83 
+T84	Date 2400 2414	next day after
+E41	Date:T84 
+T85	Clinical_event 2419 2428	discharge
+E42	Clinical_event:T85 
+T86	Diagnostic_procedure 1433 1445	Angiographic
+E43	Diagnostic_procedure:T86 
+T87	Sign_symptom 1468 1478	dissection
+E44	Sign_symptom:T87 
+A2	POLARITY E44 NEG
+T88	Therapeutic_procedure 1499 1504	stent
+E45	Therapeutic_procedure:T88 
+T89	Therapeutic_procedure 1551 1567	balloon catheter
+E46	Therapeutic_procedure:T89 
+T90	Detailed_description 1522 1533	5.0 × 15-mm
+T91	Detailed_description 1534 1550	Quantum Maverick
+R46	MODIFY Arg1:T91 Arg2:E46	
+R47	MODIFY Arg1:T90 Arg2:E46	
+T92	Diagnostic_procedure 1621 1632	angiography
+E47	Diagnostic_procedure:T92 
+T93	Therapeutic_procedure 1639 1644	stent
+E48	Therapeutic_procedure:T93 
+T94	Sign_symptom 1593 1603	dissection
+E49	Sign_symptom:T94 
+A3	POLARITY E49 NEG
+T95	Detailed_description 1584 1592	residual
+T96	Detailed_description 1459 1467	residual
+R48	MODIFY Arg1:T96 Arg2:E44	
+R49	MODIFY Arg1:T95 Arg2:E49	
+T97	Therapeutic_procedure 1703 1714	angioplasty
+E50	Therapeutic_procedure:T97 
+T98	Detailed_description 1687 1702	kissing balloon
+T99	Biological_structure 1678 1686	LMCA-LCX
+T100	Biological_structure 1665 1673	LMCA-LAD
+R50	MODIFY Arg1:T98 Arg2:E50	
+R51	MODIFY Arg1:T99 Arg2:E50	
+R52	MODIFY Arg1:T100 Arg2:E50	
+T101	Therapeutic_procedure 1764 1771	balloon
+E51	Therapeutic_procedure:T101 
+T102	Therapeutic_procedure 1813 1820	balloon
+E52	Therapeutic_procedure:T102 
+T103	Biological_structure 1779 1782	LAD
+T104	Biological_structure 1858 1861	LCX
+R53	MODIFY Arg1:T104 Arg2:E52	
+R54	MODIFY Arg1:T103 Arg2:E51	
+T105	Detailed_description 1749 1763	stent delivery
+T106	Detailed_description 1737 1748	4.0 × 28-mm
+R55	MODIFY Arg1:T105 Arg2:E51	
+R56	MODIFY Arg1:T106 Arg2:E51	
+T107	Detailed_description 1789 1803	3.0 mm × 15-mm
+T108	Detailed_description 1804 1812	Ikazuchi
+R57	MODIFY Arg1:T108 Arg2:E52	
+R58	MODIFY Arg1:T107 Arg2:E52	
+T109	Detailed_description 1822 1849	Kaneka Medics, Tokyo, Japan
+R59	MODIFY Arg1:T109 Arg2:E52	
+T110	Diagnostic_procedure 1873 1885	angiographic
+E53	Diagnostic_procedure:T110 
+T111	Diagnostic_procedure 1909 1916	results
+E54	Diagnostic_procedure:T111 
+T112	Lab_value 1901 1908	optimal
+E55	Lab_value:T112 
+R60	MODIFY Arg1:E55 Arg2:E54	
+T113	Diagnostic_procedure 1922 1926	IVUS
+E56	Diagnostic_procedure:T113 
+T114	Sign_symptom 1942 1948	lesion
+E57	Sign_symptom:T114 
+T115	Therapeutic_procedure 1982 1987	stent
+E58	Therapeutic_procedure:T115 
+T116	Diagnostic_procedure 1967 1974	sealing
+E59	Diagnostic_procedure:T116 
+T117	Lab_value 1956 1966	completely
+E60	Lab_value:T117 
+R61	MODIFY Arg1:E60 Arg2:E59	
+T118	Sign_symptom 2005 2013	hematoma
+E61	Sign_symptom:T118 
+T119	Severity 1999 2004	large
+R62	MODIFY Arg1:T119 Arg2:E61	
+T120	Sign_symptom 2053 2061	bleeding
+E62	Sign_symptom:T120 
+T121	Detailed_description 2047 2052	local
+R63	MODIFY Arg1:T121 Arg2:E62	
+T122	Sign_symptom 2167 2175	hematoma
+E63	Sign_symptom:T122 
+T123	Clinical_event 2239 2249	discharged
+E64	Clinical_event:T123 
+T124	Nonbiological_location 2259 2267	hospital
+R64	MODIFY Arg1:T124 Arg2:E64	
+T125	Date 2275 2290	fifth day after
+E65	Date:T125 
+T126	Therapeutic_procedure 2291 2294	PCI
+E66	Therapeutic_procedure:T126 
+T127	Therapeutic_procedure 2096 2110	femoral sheath
+E67	Therapeutic_procedure:T127 
+A4	POLARITY E67 NEG
+T128	Therapeutic_procedure 2115 2133	manual compression
+E68	Therapeutic_procedure:T128 
+T129	Therapeutic_procedure 2150 2161	haemostasis
+E69	Therapeutic_procedure:T129 
+R65	SUB_PROCEDURE Arg1:E68 Arg2:E69	
+T130	Biological_structure 2021 2042	femoral puncture site
+R66	MODIFY Arg1:T130 Arg2:E61	
+T131	Diagnostic_procedure 2475 2492	Electrocardiogram
+E70	Diagnostic_procedure:T131 
+T132	Sign_symptom 2500 2512	ST elevation
+E71	Sign_symptom:T132 
+T133	Diagnostic_procedure 2516 2527	leads V1-V3
+E72	Diagnostic_procedure:T133 
+R67	SUB_PROCEDURE Arg1:E72 Arg2:E70	
+T134	Diagnostic_procedure 2538 2554	echocardiography
+E73	Diagnostic_procedure:T134 
+T135	Sign_symptom 2607 2611	mass
+E74	Sign_symptom:T135 
+T136	Therapeutic_procedure 3088 3095	surgery
+E75	Therapeutic_procedure:T136 
+T137	Therapeutic_procedure 3198 3205	surgery
+E76	Therapeutic_procedure:T137 
+T138	Sign_symptom 3223 3228	clots
+E77	Sign_symptom:T138 
+T139	Color 3214 3222	dark red
+T140	Severity 3207 3212	large
+R68	MODIFY Arg1:T139 Arg2:E77	
+R69	MODIFY Arg1:T140 Arg2:E77	
+T141	Detailed_description 972 1017	Abbott Vascular, Santa Clara, California, USA
+T142	Detailed_description 751 785	Boston Scientific, Natick, MA, USA
+R70	MODIFY Arg1:T141 Arg2:E26	
+R71	MODIFY Arg1:T142 Arg2:E24	
+T143	Detailed_description 1253 1270	Boston Scientific
+T144	Detailed_description 1390 1405	Abbott Vascular
+R72	MODIFY Arg1:T143 Arg2:E31	
+R73	MODIFY Arg1:T144 Arg2:E35	
+T145	Sign_symptom 2589 2597	asynergy
+E78	Sign_symptom:T145 
+A5	POLARITY E78 NEG
+T146	Biological_structure 2572 2588	left ventricular
+R74	MODIFY Arg1:T146 Arg2:E78	
+T147	Biological_structure 2619 2661	outflow tract of right ventricular chamber
+R75	MODIFY Arg1:T147 Arg2:E74	
+T148	Diagnostic_procedure 2702 2721	computed tomography
+E79	Diagnostic_procedure:T148 
+T149	Detailed_description 2684 2701	Contrast-enhanced
+R76	MODIFY Arg1:T149 Arg2:E79	
+T150	Distance 2731 2736	40-mm
+T151	Sign_symptom 2737 2745	hematoma
+E80	Sign_symptom:T151 
+R77	MODIFY Arg1:T150 Arg2:E80	
+T152	Biological_structure 2762 2789	main pulmonary artery trunk
+T153	Biological_structure 2798 2813	right ventricle
+T154	Sign_symptom 2746 2757	compressing
+E81	Sign_symptom:T154 
+R78	CAUSE Arg1:E80 Arg2:E81	
+R79	MODIFY Arg1:T152 Arg2:E81	
+R80	MODIFY Arg1:T153 Arg2:E81	
+T155	Diagnostic_procedure 2830 2841	examination
+E82	Diagnostic_procedure:T155 
+T156	Disease_disorder 2871 2893	cardiopulmonary arrest
+E83	Disease_disorder:T156 
+T157	Detailed_description 2864 2870	sudden
+R81	MODIFY Arg1:T157 Arg2:E83	
+T158	Therapeutic_procedure 2917 2946	cardiopulmonary resuscitation
+E84	Therapeutic_procedure:T158 
+T159	Detailed_description 2907 2916	immediate
+R82	MODIFY Arg1:T159 Arg2:E84	
+T160	Therapeutic_procedure 3025 3055	cardiopulmonary support device
+E85	Therapeutic_procedure:T160 
+T161	Detailed_description 3012 3024	percutaneous
+R83	MODIFY Arg1:T161 Arg2:E85	
+T162	Sign_symptom 2963 2986	spontaneous circulation
+E86	Sign_symptom:T162 
+T163	Detailed_description 3079 3087	emergent
+R84	MODIFY Arg1:T163 Arg2:E75	
+T164	Sign_symptom 3119 3127	hematoma
+E87	Sign_symptom:T164 
+T165	Biological_structure 3241 3263	pulmonary artery trunk
+T166	Biological_structure 3268 3273	aorta
+R85	MODIFY Arg1:T165 Arg2:E77	
+R86	MODIFY Arg1:T166 Arg2:E77	
+T167	Sign_symptom 3328 3336	hematoma
+E88	Sign_symptom:T167 
+T168	Biological_structure 3363 3378	LMCA stent site
+T169	Biological_structure 3317 3327	epicardial
+R87	MODIFY Arg1:T169 Arg2:E88	
+T170	Sign_symptom 3341 3353	blood oozing
+E89	Sign_symptom:T170 
+R88	CAUSE Arg1:E89 Arg2:E88	
+R89	MODIFY Arg1:T168 Arg2:E89	
+*	OVERLAP E1 E3 E2
+R90	AFTER Arg1:E2 Arg2:E5	
+*	OVERLAP E5 E7 E4 E8
+R91	MODIFY Arg1:T14 Arg2:E5	
+R92	MODIFY Arg1:T16 Arg2:E5	
+R93	BEFORE Arg1:E8 Arg2:E13	
+R94	BEFORE Arg1:E13 Arg2:E14	
+*	OVERLAP E14 E15 E16 E18 E19 E21 E22 E23 E24 E25 E26 E27 E29 E30 E31 E32
+T171	Detailed_description 867 893	Asahi Intecc, Aichi, Japan
+R95	MODIFY Arg1:T171 Arg2:E25	
+T172	Detailed_description 1102 1127	Terumo Corp, Tokyo, Japan
+R96	MODIFY Arg1:T172 Arg2:E27	
+R97	MODIFY Arg1:T70 Arg2:E33	
+R98	BEFORE Arg1:E32 Arg2:E33	
+*	OVERLAP E33 E34 E35
+R99	BEFORE Arg1:E35 Arg2:E43	
+*	OVERLAP E43 E44 E45 E46 E49 E47
+R100	AFTER Arg1:E47 Arg2:E48	
+R101	BEFORE Arg1:E48 Arg2:E50	
+*	OVERLAP E50 E51 E52
+R102	BEFORE Arg1:E52 Arg2:E53	
+*	OVERLAP E53 E54 E56 E57 E59 E58
+R103	BEFORE Arg1:E58 Arg2:E61	
+*	OVERLAP E61 E62
+R104	AFTER Arg1:E62 Arg2:E67	
+R105	BEFORE Arg1:E67 Arg2:E68	
+R106	BEFORE Arg1:E68 Arg2:E63	
+T173	Date 2206 2218	the next day
+E90	Date:T173 
+A6	TREND E63 STAY
+*	OVERLAP E63 E90
+R107	BEFORE Arg1:E90 Arg2:E64	
+*	OVERLAP E64 E65
+R108	AFTER Arg1:E65 Arg2:E66	
+R109	BEFORE Arg1:E66 Arg2:E38	
+*	OVERLAP E38 E39 E40 E41
+R110	AFTER Arg1:E41 Arg2:E42	
+R111	BEFORE Arg1:E42 Arg2:E36	
+*	OVERLAP E36 E37 E70 E73 E78 E74 E79 E80 E81 E82 E83
+R112	BEFORE Arg1:E83 Arg2:E84	
+R113	BEFORE Arg1:E84 Arg2:E86	
+R114	AFTER Arg1:E86 Arg2:E85	
+R115	BEFORE Arg1:E85 Arg2:E75	
+*	OVERLAP E75 E87 E76 E77 E88 E89 E20
+R116	BEFORE Arg1:E20 Arg2:E10	
+*	OVERLAP E10 E12 E11