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T1 Age 2 13 70-year-old T2 Sex 14 18 male T3 Clinical_event 23 31 admitted E1 Clinical_event:T3 T4 Disease_disorder 105 113 aneurysm E2 Disease_disorder:T4 T5 Biological_structure 88 104 abdominal aortic R1 MODIFY Arg1:T5 Arg2:E2 T6 Diagnostic_procedure 66 84 cardiac evaluation E3 Diagnostic_procedure:T6 T7 Date 240 254 4 years before E4 Date:T7 T8 Therapeutic_procedure 141 172 coronary artery bypass grafting E5 Therapeutic_procedure:T8 T9 Therapeutic_procedure 174 178 CABG E6 Therapeutic_procedure:T9 R2 IDENTICAL Arg1:E6 Arg2:E5 T10 Sign_symptom 191 199 stenosis E7 Sign_symptom:T10 T11 Severity 184 190 severe R3 MODIFY Arg1:T11 Arg2:E7 T12 Biological_structure 207 232 left main coronary artery T13 Biological_structure 234 238 LMCA R4 IDENTICAL Arg1:T13 Arg2:T12 R5 MODIFY Arg1:T12 Arg2:E7 T14 Biological_structure 279 309 right internal thoracic artery T15 Biological_structure 311 315 RITA R6 IDENTICAL Arg1:T15 Arg2:T14 T16 Biological_structure 324 355 left anterior descending artery T17 Biological_structure 357 360 LAD R7 MODIFY Arg1:T17 Arg2:T16 T18 Therapeutic_procedure 366 386 saphenous vein graft E8 Therapeutic_procedure:T18 T19 Therapeutic_procedure 388 391 SVG E9 Therapeutic_procedure:T19 R8 IDENTICAL Arg1:E9 Arg2:E8 T20 Biological_structure 400 422 left circumflex artery T21 Biological_structure 424 427 LCX R9 IDENTICAL Arg1:T21 Arg2:T20 T22 Outcome 3428 3432 died E10 Outcome:T22 T23 Therapeutic_procedure 3464 3488 external cardiac massage E11 Therapeutic_procedure:T23 T24 Disease_disorder 3438 3452 aortic rupture E12 Disease_disorder:T24 R10 CAUSE Arg1:E11 Arg2:E12 R11 CAUSE Arg1:E12 Arg2:E10 T25 Detailed_description 52 65 perioperative R12 MODIFY Arg1:T25 Arg2:E3 T26 Disease_disorder 478 486 aneurysm E13 Disease_disorder:T26 A1 TREND E13 INC T27 Therapeutic_procedure 503 510 surgery E14 Therapeutic_procedure:T27 T28 Biological_structure 461 477 abdominal aortic R13 MODIFY Arg1:T28 Arg2:E13 T31 Diagnostic_procedure 540 549 angiogram E15 Diagnostic_procedure:T31 T32 Biological_structure 526 539 Left coronary R16 MODIFY Arg1:T32 Arg2:E15 T29 Sign_symptom 562 570 stenosis E16 Sign_symptom:T29 T30 Lab_value 557 561 90 % E17 Lab_value:T30 R14 MODIFY Arg1:E17 Arg2:E16 T33 Biological_structure 578 582 LMCA R15 MODIFY Arg1:T33 Arg2:E16 T34 Sign_symptom 593 602 occlusion E18 Sign_symptom:T34 T35 Severity 587 592 total R17 MODIFY Arg1:T35 Arg2:E18 T36 Coreference 611 617 grafts E19 Coreference:T36 R18 IDENTICAL Arg1:E19 Arg2:E8 T37 Detailed_description 606 610 both R19 MODIFY Arg1:T37 Arg2:E19 T38 Biological_structure 641 645 LMCA T39 Therapeutic_procedure 3399 3414 surgical repair E20 Therapeutic_procedure:T39 T40 Therapeutic_procedure 619 622 PCI E21 Therapeutic_procedure:T40 #1 AnnotatorNotes E21 Percutaneous coronary intervention T41 Sign_symptom 646 654 stenosis E22 Sign_symptom:T41 R20 MODIFY Arg1:T38 Arg2:E22 T42 Therapeutic_procedure 671 677 sheath E23 Therapeutic_procedure:T42 T43 Detailed_description 666 670 7-Fr R21 MODIFY Arg1:T43 Arg2:E23 T44 Biological_structure 700 720 right femoral artery R22 MODIFY Arg1:T44 Arg2:E23 T45 Therapeutic_procedure 741 749 catheter E24 Therapeutic_procedure:T45 T46 Detailed_description 733 740 guiding T47 Detailed_description 728 732 CLS4 R23 MODIFY Arg1:T46 Arg2:E24 R24 MODIFY Arg1:T47 Arg2:E24 T48 Biological_structure 808 828 left coronary artery T49 Biological_structure 830 833 LCA T50 Biological_structure 835 841 ostium R25 MODIFY Arg1:T50 Arg2:T48 R26 IDENTICAL Arg1:T49 Arg2:T48 R27 MODIFY Arg1:T48 Arg2:E24 T51 Therapeutic_procedure 845 854 guidewire E25 Therapeutic_procedure:T51 T52 Biological_structure 917 927 distal LAD R28 MODIFY Arg1:T52 Arg2:E25 T53 Therapeutic_procedure 941 950 guidewire E26 Therapeutic_procedure:T53 T54 Biological_structure 1041 1051 distal LCX R29 MODIFY Arg1:T54 Arg2:E26 T55 Diagnostic_procedure 1053 1077 Intravascular ultrasound E27 Diagnostic_procedure:T55 T56 Diagnostic_procedure 1079 1083 IVUS E28 Diagnostic_procedure:T56 R30 IDENTICAL Arg1:E28 Arg2:E27 T57 Sign_symptom 1164 1177 calcification E29 Sign_symptom:T57 T58 Severity 1142 1147 heavy R31 MODIFY Arg1:T58 Arg2:E29 T59 Sign_symptom 1190 1196 lesion E30 Sign_symptom:T59 R32 MODIFY Arg1:E29 Arg2:E30 T60 Biological_structure 1185 1189 LMCA R33 MODIFY Arg1:T60 Arg2:E30 T61 Detailed_description 1148 1163 circumferential R34 MODIFY Arg1:T61 Arg2:E29 T62 Therapeutic_procedure 1243 1251 catheter E31 Therapeutic_procedure:T62 T63 Detailed_description 1235 1242 balloon T64 Detailed_description 1218 1234 Quantum Maverick T65 Detailed_description 1206 1217 4.0 × 15-mm R35 MODIFY Arg1:T63 Arg2:E31 R36 MODIFY Arg1:T64 Arg2:E31 R37 MODIFY Arg1:T65 Arg2:E31 T66 Detailed_description 1086 1100 Intra-focus WR T67 Detailed_description 952 970 Hi-Torque Pilot 50 T68 Detailed_description 856 865 SION Blue R38 MODIFY Arg1:T68 Arg2:E25 R39 MODIFY Arg1:T67 Arg2:E26 R40 MODIFY Arg1:T66 Arg2:E28 T69 Sign_symptom 1292 1298 lesion E32 Sign_symptom:T69 T70 Biological_structure 1300 1303 LCA T71 Diagnostic_procedure 1304 1313 angiogram E33 Diagnostic_procedure:T71 T72 Sign_symptom 1331 1341 dissection E34 Sign_symptom:T72 T73 Severity 1325 1330 large R41 MODIFY Arg1:T73 Arg2:E34 T74 Therapeutic_procedure 1383 1388 stent E35 Therapeutic_procedure:T74 T75 Detailed_description 1365 1382 Multi-Link Vision T76 Detailed_description 1353 1364 4.0 × 28-mm R42 MODIFY Arg1:T75 Arg2:E35 R43 MODIFY Arg1:T76 Arg2:E35 T77 Diagnostic_procedure 2434 2445 vital signs E36 Diagnostic_procedure:T77 T78 Sign_symptom 2456 2473 cardiogenic shock E37 Sign_symptom:T78 T79 Clinical_event 2326 2334 admitted E38 Clinical_event:T79 T80 Nonbiological_location 2342 2356 emergency room R44 MODIFY Arg1:T80 Arg2:E38 T81 Sign_symptom 2378 2382 pain E39 Sign_symptom:T81 T82 Biological_structure 2372 2377 chest R45 MODIFY Arg1:T82 Arg2:E39 T83 Sign_symptom 2387 2395 dyspnoea E40 Sign_symptom:T83 T84 Date 2400 2414 next day after E41 Date:T84 T85 Clinical_event 2419 2428 discharge E42 Clinical_event:T85 T86 Diagnostic_procedure 1433 1445 Angiographic E43 Diagnostic_procedure:T86 T87 Sign_symptom 1468 1478 dissection E44 Sign_symptom:T87 A2 POLARITY E44 NEG T88 Therapeutic_procedure 1499 1504 stent E45 Therapeutic_procedure:T88 T89 Therapeutic_procedure 1551 1567 balloon catheter E46 Therapeutic_procedure:T89 T90 Detailed_description 1522 1533 5.0 × 15-mm T91 Detailed_description 1534 1550 Quantum Maverick R46 MODIFY Arg1:T91 Arg2:E46 R47 MODIFY Arg1:T90 Arg2:E46 T92 Diagnostic_procedure 1621 1632 angiography E47 Diagnostic_procedure:T92 T93 Therapeutic_procedure 1639 1644 stent E48 Therapeutic_procedure:T93 T94 Sign_symptom 1593 1603 dissection E49 Sign_symptom:T94 A3 POLARITY E49 NEG T95 Detailed_description 1584 1592 residual T96 Detailed_description 1459 1467 residual R48 MODIFY Arg1:T96 Arg2:E44 R49 MODIFY Arg1:T95 Arg2:E49 T97 Therapeutic_procedure 1703 1714 angioplasty E50 Therapeutic_procedure:T97 T98 Detailed_description 1687 1702 kissing balloon T99 Biological_structure 1678 1686 LMCA-LCX T100 Biological_structure 1665 1673 LMCA-LAD R50 MODIFY Arg1:T98 Arg2:E50 R51 MODIFY Arg1:T99 Arg2:E50 R52 MODIFY Arg1:T100 Arg2:E50 T101 Therapeutic_procedure 1764 1771 balloon E51 Therapeutic_procedure:T101 T102 Therapeutic_procedure 1813 1820 balloon E52 Therapeutic_procedure:T102 T103 Biological_structure 1779 1782 LAD T104 Biological_structure 1858 1861 LCX R53 MODIFY Arg1:T104 Arg2:E52 R54 MODIFY Arg1:T103 Arg2:E51 T105 Detailed_description 1749 1763 stent delivery T106 Detailed_description 1737 1748 4.0 × 28-mm R55 MODIFY Arg1:T105 Arg2:E51 R56 MODIFY Arg1:T106 Arg2:E51 T107 Detailed_description 1789 1803 3.0 mm × 15-mm T108 Detailed_description 1804 1812 Ikazuchi R57 MODIFY Arg1:T108 Arg2:E52 R58 MODIFY Arg1:T107 Arg2:E52 T109 Detailed_description 1822 1849 Kaneka Medics, Tokyo, Japan R59 MODIFY Arg1:T109 Arg2:E52 T110 Diagnostic_procedure 1873 1885 angiographic E53 Diagnostic_procedure:T110 T111 Diagnostic_procedure 1909 1916 results E54 Diagnostic_procedure:T111 T112 Lab_value 1901 1908 optimal E55 Lab_value:T112 R60 MODIFY Arg1:E55 Arg2:E54 T113 Diagnostic_procedure 1922 1926 IVUS E56 Diagnostic_procedure:T113 T114 Sign_symptom 1942 1948 lesion E57 Sign_symptom:T114 T115 Therapeutic_procedure 1982 1987 stent E58 Therapeutic_procedure:T115 T116 Diagnostic_procedure 1967 1974 sealing E59 Diagnostic_procedure:T116 T117 Lab_value 1956 1966 completely E60 Lab_value:T117 R61 MODIFY Arg1:E60 Arg2:E59 T118 Sign_symptom 2005 2013 hematoma E61 Sign_symptom:T118 T119 Severity 1999 2004 large R62 MODIFY Arg1:T119 Arg2:E61 T120 Sign_symptom 2053 2061 bleeding E62 Sign_symptom:T120 T121 Detailed_description 2047 2052 local R63 MODIFY Arg1:T121 Arg2:E62 T122 Sign_symptom 2167 2175 hematoma E63 Sign_symptom:T122 T123 Clinical_event 2239 2249 discharged E64 Clinical_event:T123 T124 Nonbiological_location 2259 2267 hospital R64 MODIFY Arg1:T124 Arg2:E64 T125 Date 2275 2290 fifth day after E65 Date:T125 T126 Therapeutic_procedure 2291 2294 PCI E66 Therapeutic_procedure:T126 T127 Therapeutic_procedure 2096 2110 femoral sheath E67 Therapeutic_procedure:T127 A4 POLARITY E67 NEG T128 Therapeutic_procedure 2115 2133 manual compression E68 Therapeutic_procedure:T128 T129 Therapeutic_procedure 2150 2161 haemostasis E69 Therapeutic_procedure:T129 R65 SUB_PROCEDURE Arg1:E68 Arg2:E69 T130 Biological_structure 2021 2042 femoral puncture site R66 MODIFY Arg1:T130 Arg2:E61 T131 Diagnostic_procedure 2475 2492 Electrocardiogram E70 Diagnostic_procedure:T131 T132 Sign_symptom 2500 2512 ST elevation E71 Sign_symptom:T132 T133 Diagnostic_procedure 2516 2527 leads V1-V3 E72 Diagnostic_procedure:T133 R67 SUB_PROCEDURE Arg1:E72 Arg2:E70 T134 Diagnostic_procedure 2538 2554 echocardiography E73 Diagnostic_procedure:T134 T135 Sign_symptom 2607 2611 mass E74 Sign_symptom:T135 T136 Therapeutic_procedure 3088 3095 surgery E75 Therapeutic_procedure:T136 T137 Therapeutic_procedure 3198 3205 surgery E76 Therapeutic_procedure:T137 T138 Sign_symptom 3223 3228 clots E77 Sign_symptom:T138 T139 Color 3214 3222 dark red T140 Severity 3207 3212 large R68 MODIFY Arg1:T139 Arg2:E77 R69 MODIFY Arg1:T140 Arg2:E77 T141 Detailed_description 972 1017 Abbott Vascular, Santa Clara, California, USA T142 Detailed_description 751 785 Boston Scientific, Natick, MA, USA R70 MODIFY Arg1:T141 Arg2:E26 R71 MODIFY Arg1:T142 Arg2:E24 T143 Detailed_description 1253 1270 Boston Scientific T144 Detailed_description 1390 1405 Abbott Vascular R72 MODIFY Arg1:T143 Arg2:E31 R73 MODIFY Arg1:T144 Arg2:E35 T145 Sign_symptom 2589 2597 asynergy E78 Sign_symptom:T145 A5 POLARITY E78 NEG T146 Biological_structure 2572 2588 left ventricular R74 MODIFY Arg1:T146 Arg2:E78 T147 Biological_structure 2619 2661 outflow tract of right ventricular chamber R75 MODIFY Arg1:T147 Arg2:E74 T148 Diagnostic_procedure 2702 2721 computed tomography E79 Diagnostic_procedure:T148 T149 Detailed_description 2684 2701 Contrast-enhanced R76 MODIFY Arg1:T149 Arg2:E79 T150 Distance 2731 2736 40-mm T151 Sign_symptom 2737 2745 hematoma E80 Sign_symptom:T151 R77 MODIFY Arg1:T150 Arg2:E80 T152 Biological_structure 2762 2789 main pulmonary artery trunk T153 Biological_structure 2798 2813 right ventricle T154 Sign_symptom 2746 2757 compressing E81 Sign_symptom:T154 R78 CAUSE Arg1:E80 Arg2:E81 R79 MODIFY Arg1:T152 Arg2:E81 R80 MODIFY Arg1:T153 Arg2:E81 T155 Diagnostic_procedure 2830 2841 examination E82 Diagnostic_procedure:T155 T156 Disease_disorder 2871 2893 cardiopulmonary arrest E83 Disease_disorder:T156 T157 Detailed_description 2864 2870 sudden R81 MODIFY Arg1:T157 Arg2:E83 T158 Therapeutic_procedure 2917 2946 cardiopulmonary resuscitation E84 Therapeutic_procedure:T158 T159 Detailed_description 2907 2916 immediate R82 MODIFY Arg1:T159 Arg2:E84 T160 Therapeutic_procedure 3025 3055 cardiopulmonary support device E85 Therapeutic_procedure:T160 T161 Detailed_description 3012 3024 percutaneous R83 MODIFY Arg1:T161 Arg2:E85 T162 Sign_symptom 2963 2986 spontaneous circulation E86 Sign_symptom:T162 T163 Detailed_description 3079 3087 emergent R84 MODIFY Arg1:T163 Arg2:E75 T164 Sign_symptom 3119 3127 hematoma E87 Sign_symptom:T164 T165 Biological_structure 3241 3263 pulmonary artery trunk T166 Biological_structure 3268 3273 aorta R85 MODIFY Arg1:T165 Arg2:E77 R86 MODIFY Arg1:T166 Arg2:E77 T167 Sign_symptom 3328 3336 hematoma E88 Sign_symptom:T167 T168 Biological_structure 3363 3378 LMCA stent site T169 Biological_structure 3317 3327 epicardial R87 MODIFY Arg1:T169 Arg2:E88 T170 Sign_symptom 3341 3353 blood oozing E89 Sign_symptom:T170 R88 CAUSE Arg1:E89 Arg2:E88 R89 MODIFY Arg1:T168 Arg2:E89 * OVERLAP E1 E3 E2 R90 AFTER Arg1:E2 Arg2:E5 * OVERLAP E5 E7 E4 E8 R91 MODIFY Arg1:T14 Arg2:E5 R92 MODIFY Arg1:T16 Arg2:E5 R93 BEFORE Arg1:E8 Arg2:E13 R94 BEFORE Arg1:E13 Arg2:E14 * OVERLAP E14 E15 E16 E18 E19 E21 E22 E23 E24 E25 E26 E27 E29 E30 E31 E32 T171 Detailed_description 867 893 Asahi Intecc, Aichi, Japan R95 MODIFY Arg1:T171 Arg2:E25 T172 Detailed_description 1102 1127 Terumo Corp, Tokyo, Japan R96 MODIFY Arg1:T172 Arg2:E27 R97 MODIFY Arg1:T70 Arg2:E33 R98 BEFORE Arg1:E32 Arg2:E33 * OVERLAP E33 E34 E35 R99 BEFORE Arg1:E35 Arg2:E43 * OVERLAP E43 E44 E45 E46 E49 E47 R100 AFTER Arg1:E47 Arg2:E48 R101 BEFORE Arg1:E48 Arg2:E50 * OVERLAP E50 E51 E52 R102 BEFORE Arg1:E52 Arg2:E53 * OVERLAP E53 E54 E56 E57 E59 E58 R103 BEFORE Arg1:E58 Arg2:E61 * OVERLAP E61 E62 R104 AFTER Arg1:E62 Arg2:E67 R105 BEFORE Arg1:E67 Arg2:E68 R106 BEFORE Arg1:E68 Arg2:E63 T173 Date 2206 2218 the next day E90 Date:T173 A6 TREND E63 STAY * OVERLAP E63 E90 R107 BEFORE Arg1:E90 Arg2:E64 * OVERLAP E64 E65 R108 AFTER Arg1:E65 Arg2:E66 R109 BEFORE Arg1:E66 Arg2:E38 * OVERLAP E38 E39 E40 E41 R110 AFTER Arg1:E41 Arg2:E42 R111 BEFORE Arg1:E42 Arg2:E36 * OVERLAP E36 E37 E70 E73 E78 E74 E79 E80 E81 E82 E83 R112 BEFORE Arg1:E83 Arg2:E84 R113 BEFORE Arg1:E84 Arg2:E86 R114 AFTER Arg1:E86 Arg2:E85 R115 BEFORE Arg1:E85 Arg2:E75 * OVERLAP E75 E87 E76 E77 E88 E89 E20 R116 BEFORE Arg1:E20 Arg2:E10 * OVERLAP E10 E12 E11