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+T1	Age 2 13	30-year-old
+T2	Sex 14 19	woman
+T3	History 38 41	HIV
+T4	History 46 49	HCV
+#1	AnnotatorNotes T4	Hepatitis C
+T5	Clinical_event 50 59	presented
+E1	Clinical_event:T5 
+T6	Disease_disorder 38 41	HIV
+E2	Disease_disorder:T6 
+T7	Disease_disorder 46 49	HCV
+E3	Disease_disorder:T7 
+T8	Nonbiological_location 67 87	emergency department
+R1	MODIFY Arg1:T8 Arg2:E1	
+T9	Duration 95 102	4-month
+E4	Duration:T9 
+T10	Sign_symptom 138 146	swelling
+E5	Sign_symptom:T10 
+T11	Biological_structure 154 165	lower limbs
+T12	Biological_structure 170 177	abdomen
+R2	MODIFY Arg1:T11 Arg2:E5	
+R3	MODIFY Arg1:T12 Arg2:E5	
+T13	Detailed_description 126 137	progressive
+T14	Detailed_description 114 121	gradual
+A1	TREND E5 INC
+R4	MODIFY Arg1:T13 Arg2:E5	
+R5	MODIFY Arg1:T14 Arg2:E5	
+T15	Sign_symptom 200 204	pain
+E6	Sign_symptom:T15 
+A2	POLARITY E6 NEG
+T16	Biological_structure 194 199	chest
+R6	MODIFY Arg1:T16 Arg2:E6	
+T17	Sign_symptom 206 214	dyspnoea
+E7	Sign_symptom:T17 
+A3	POLARITY E7 NEG
+T18	Sign_symptom 237 245	dyspnoea
+E8	Sign_symptom:T18 
+A4	POLARITY E8 NEG
+T19	Sign_symptom 249 259	orthopnoea
+E9	Sign_symptom:T19 
+A5	POLARITY E9 NEG
+T20	Detailed_description 227 236	nocturnal
+T21	Detailed_description 216 226	paroxysmal
+R7	MODIFY Arg1:T20 Arg2:E8	
+R8	MODIFY Arg1:T21 Arg2:E8	
+T22	Diagnostic_procedure 261 267	Vitals
+E10	Diagnostic_procedure:T22 
+T23	Lab_value 273 279	stable
+E11	Lab_value:T23 
+R9	MODIFY Arg1:E11 Arg2:E10	
+T24	Diagnostic_procedure 281 307	Cardiovascular examination
+E12	Diagnostic_procedure:T24 
+T25	Diagnostic_procedure 339 362	jugular venous pressure
+E13	Diagnostic_procedure:T25 
+T26	Diagnostic_procedure 364 367	JVP
+E14	Diagnostic_procedure:T26 
+R10	IDENTICAL Arg1:E14 Arg2:E13	
+T27	Lab_value 330 338	elevated
+E15	Lab_value:T27 
+R11	MODIFY Arg1:E15 Arg2:E13	
+T28	Lab_value 378 383	12 cm
+E16	Lab_value:T28 
+R12	MODIFY Arg1:E16 Arg2:E13	
+T29	Lab_value 391 413	pronounced ‘y’ descent
+E17	Lab_value:T29 
+R13	MODIFY Arg1:E17 Arg2:E13	
+T30	Sign_symptom 437 460	pericardial knock sound
+E18	Sign_symptom:T30 
+T31	Biological_structure 476 487	praecordium
+R14	MODIFY Arg1:T31 Arg2:E18	
+T32	Severity 427 436	prominent
+R15	MODIFY Arg1:T32 Arg2:E18	
+T33	Sign_symptom 502 517	pericardial rub
+E19	Sign_symptom:T33 
+A6	POLARITY E19 NEG
+T34	Sign_symptom 521 527	murmur
+E20	Sign_symptom:T34 
+A7	POLARITY E20 NEG
+T35	Diagnostic_procedure 553 565	auscultation
+E21	Diagnostic_procedure:T35 
+T36	Biological_structure 533 538	lungs
+R16	MODIFY Arg1:T36 Arg2:E21	
+T37	Lab_value 544 549	clear
+E22	Lab_value:T37 
+R17	MODIFY Arg1:E22 Arg2:E21	
+T38	Sign_symptom 592 602	oedematous
+E23	Sign_symptom:T38 
+T39	Biological_structure 612 619	abdomen
+T40	Biological_structure 627 638	lower limbs
+R18	MODIFY Arg1:T39 Arg2:E23	
+R19	MODIFY Arg1:T40 Arg2:E23	
+T41	Clinical_event 648 656	admitted
+E24	Clinical_event:T41 
+T42	Diagnostic_procedure 669 687	diagnostic work-up
+E25	Diagnostic_procedure:T42 
+T43	Therapeutic_procedure 692 702	management
+E26	Therapeutic_procedure:T43 
+T44	Disease_disorder 727 730	HIV
+E27	Disease_disorder:T44 
+T45	History 727 730	HIV
+R20	MODIFY Arg1:E4 Arg2:E5	
+T46	Date 738 746	May 2010
+E28	Date:T46 
+T47	Medication 763 785	antiretroviral therapy
+E29	Medication:T47 
+T48	Activity 804 817	illicit drugs
+E30	Activity:T48 
+A8	POLARITY E30 NEG
+T49	Duration 822 845	approximately 5–6 years
+E31	Duration:T49 
+R21	MODIFY Arg1:E31 Arg2:E30	
+T50	Disease_disorder 847 873	Renal and hepatic diseases
+E32	Disease_disorder:T50 
+A9	POLARITY E32 NEG
+T51	Diagnostic_procedure 897 908	blood tests
+E33	Diagnostic_procedure:T51 
+T52	Diagnostic_procedure 913 920	imaging
+E34	Diagnostic_procedure:T52 
+T53	Disease_disorder 956 966	malignancy
+E35	Disease_disorder:T53 
+A10	POLARITY E35 NEG
+T54	Biological_structure 922 938	Peritoneal fluid
+R22	MODIFY Arg1:T54 Arg2:E35	
+T55	Diagnostic_procedure 968 982	Echocardiogram
+E36	Diagnostic_procedure:T55 
+T56	Biological_structure 1009 1020	pericardium
+T57	Biological_structure 1037 1055	right heart border
+R23	MODIFY Arg1:T56 Arg2:E36	
+R24	MODIFY Arg1:T57 Arg2:E36	
+T58	Lab_value 1002 1008	bright
+E37	Lab_value:T58 
+T59	Lab_value 992 1001	thickened
+E38	Lab_value:T59 
+R25	MODIFY Arg1:E37 Arg2:T56	
+R26	MODIFY Arg1:E38 Arg2:T56	
+T60	Lab_value 1157 1170	septal bounce
+E39	Lab_value:T60 
+R27	MODIFY Arg1:E39 Arg2:E36	
+T61	Lab_value 1183 1200	pericardial slide
+E40	Lab_value:T61 
+A11	POLARITY E40 NEG
+R28	MODIFY Arg1:E40 Arg2:E36	
+T62	Lab_value 1072 1133	parallel separation between epicardial and pericardial echoes
+E41	Lab_value:T62 
+R29	MODIFY Arg1:E41 Arg2:E36	
+T63	Diagnostic_procedure 1247 1254	Doppler
+E42	Diagnostic_procedure:T63 
+T64	Biological_structure 1240 1246	tissue
+R30	MODIFY Arg1:T64 Arg2:E42	
+T65	Sign_symptom 1202 1219	Annulus paradoxus
+E43	Sign_symptom:T65 
+T66	Diagnostic_procedure 1267 1301	Left ventricular ejection fraction
+E44	Diagnostic_procedure:T66 
+T67	Lab_value 1306 1309	64%
+E45	Lab_value:T67 
+R31	MODIFY Arg1:E45 Arg2:E44	
+T68	Diagnostic_procedure 1345 1349	size
+E46	Diagnostic_procedure:T68 
+T69	Diagnostic_procedure 1354 1362	function
+E47	Diagnostic_procedure:T69 
+T70	Biological_structure 1315 1330	right ventricle
+R32	MODIFY Arg1:T70 Arg2:E46	
+R33	MODIFY Arg1:T70 Arg2:E47	
+T71	Lab_value 1335 1341	normal
+E48	Lab_value:T71 
+R34	MODIFY Arg1:E48 Arg2:E46	
+R35	MODIFY Arg1:E48 Arg2:E47	
+T72	Sign_symptom 1383 1406	tricuspid regurgitation
+E49	Sign_symptom:T72 
+T73	Severity 1374 1382	moderate
+R36	MODIFY Arg1:T73 Arg2:E49	
+T74	Sign_symptom 1421 1441	pericardial effusion
+E50	Sign_symptom:T74 
+A12	POLARITY E50 NEG
+T75	Sign_symptom 1488 1494	debris
+E51	Sign_symptom:T75 
+T76	Biological_structure 1451 1468	pericardial space
+R37	MODIFY Arg1:T76 Arg2:E51	
+T77	Disease_disorder 1496 1519	Constrictive physiology
+E52	Disease_disorder:T77 
+T78	Diagnostic_procedure 1540 1547	Doppler
+E53	Diagnostic_procedure:T78 
+T79	Activity 1604 1615	inspiration
+E54	Activity:T79 
+T80	Activity 1620 1630	expiration
+E55	Activity:T80 
+T81	Sign_symptom 1632 1655	diastolic flow reversal
+E56	Sign_symptom:T81 
+T82	Biological_structure 1685 1698	hepatic veins
+R38	MODIFY Arg1:T82 Arg2:E56	
+T83	Activity 1706 1716	expiration
+E57	Activity:T83 
+R39	MODIFY Arg1:E57 Arg2:E56	
+T84	Other_event 1557 1585	tricuspid and mitral inflows
+E58	Other_event:T84 
+R40	MODIFY Arg1:E54 Arg2:E58	
+R41	MODIFY Arg1:E55 Arg2:E58	
+R42	MODIFY Arg1:E58 Arg2:E53	
+T85	Sign_symptom 1735 1745	dilatation
+E59	Sign_symptom:T85 
+T86	Biological_structure 1753 1771	inferior vena cava
+R43	MODIFY Arg1:T86 Arg2:E59	
+T87	Activity 1794 1805	inspiration
+E60	Activity:T87 
+T88	Activity 1809 1819	expiration
+E61	Activity:T88 
+T89	Diagnostic_procedure 1821 1823	CT
+E62	Diagnostic_procedure:T89 
+T90	Biological_structure 1831 1836	chest
+R44	MODIFY Arg1:T90 Arg2:E62	
+T91	Sign_symptom 1846 1856	thickening
+E63	Sign_symptom:T91 
+T92	Biological_structure 1864 1875	pericardium
+R45	MODIFY Arg1:T92 Arg2:E63	
+T93	Sign_symptom 1896 1909	calcification
+E64	Sign_symptom:T93 
+A13	POLARITY E64 NEG
+T94	Sign_symptom 1930 1937	nodules
+E65	Sign_symptom:T94 
+A14	POLARITY E65 NEG
+T95	Biological_structure 1925 1929	lung
+R46	MODIFY Arg1:T95 Arg2:E65	
+T96	Disease_disorder 1949 1966	pleural effusions
+E66	Disease_disorder:T96 
+T97	Detailed_description 1939 1948	Bilateral
+R47	MODIFY Arg1:T97 Arg2:E66	
+T98	Sign_symptom 1984 1994	thickening
+E67	Sign_symptom:T98 
+T99	Detailed_description 1971 1983	interstitial
+R48	MODIFY Arg1:T99 Arg2:E67	
+T100	Biological_structure 2015 2025	lung bases
+R49	MODIFY Arg1:T100 Arg2:E67	
+T101	Diagnostic_procedure 2035 2038	MRI
+E68	Diagnostic_procedure:T101 
+T102	Biological_structure 2027 2034	Cardiac
+R50	MODIFY Arg1:T102 Arg2:E68	
+T103	Biological_structure 2087 2098	pericardium
+T104	Sign_symptom 2077 2086	thickened
+E69	Sign_symptom:T104 
+T105	Detailed_description 2067 2076	diffusely
+R51	MODIFY Arg1:T105 Arg2:E69	
+R52	MODIFY Arg1:T103 Arg2:E69	
+T106	Lab_value 2102 2106	5 mm
+E70	Lab_value:T106 
+R53	MODIFY Arg1:E70 Arg2:E69	
+T107	Sign_symptom 2158 2167	plethoric
+E71	Sign_symptom:T107 
+T108	Biological_structure 2112 2130	inferior vena cava
+T109	Biological_structure 2135 2148	hepatic veins
+R54	MODIFY Arg1:T109 Arg2:E71	
+R55	MODIFY Arg1:T108 Arg2:E71	
+T110	Diagnostic_procedure 2187 2210	early diastolic filling
+E72	Diagnostic_procedure:T110 
+T111	Lab_value 2181 2186	rapid
+E73	Lab_value:T111 
+R56	MODIFY Arg1:E73 Arg2:E72	
+T112	Sign_symptom 2226 2249	diastolic septal bounce
+E74	Sign_symptom:T112 
+T113	Diagnostic_procedure 2272 2294	late diastolic filling
+E75	Diagnostic_procedure:T113 
+T114	Lab_value 2263 2271	hindered
+E76	Lab_value:T114 
+R57	MODIFY Arg1:E76 Arg2:E75	
+T115	Therapeutic_procedure 2345 2353	diuresis
+E77	Therapeutic_procedure:T115 
+T116	Diagnostic_procedure 2333 2341	response
+E78	Diagnostic_procedure:T116 
+T117	Lab_value 2328 2332	good
+E79	Lab_value:T117 
+R58	MODIFY Arg1:E79 Arg2:E78	
+T118	Therapeutic_procedure 2390 2405	catheterisation
+E80	Therapeutic_procedure:T118 
+T119	Biological_structure 2384 2389	heart
+R59	MODIFY Arg1:T119 Arg2:E80	
+T120	Detailed_description 2379 2383	left
+T121	Detailed_description 2369 2374	right
+R60	MODIFY Arg1:T120 Arg2:E80	
+R61	MODIFY Arg1:T121 Arg2:E80	
+T122	Disease_disorder 2417 2440	constrictive physiology
+E81	Disease_disorder:T122 
+*	OVERLAP E2 E3
+R62	BEFORE Arg1:E3 Arg2:E1	
+R63	AFTER Arg1:E1 Arg2:E4	
+*	OVERLAP E4 E5
+R64	BEFORE Arg1:E5 Arg2:E6	
+*	OVERLAP E6 E7 E8 E9 E10 E12 E13 E18 E19 E20 E21 E23
+R65	BEFORE Arg1:E23 Arg2:E24	
+*	OVERLAP E24 E25 E26
+R66	AFTER Arg1:E26 Arg2:E27	
+*	OVERLAP E27 E28 E29
+R67	BEFORE Arg1:E29 Arg2:E30	
+*	OVERLAP E30 E31
+R68	BEFORE Arg1:E31 Arg2:E32	
+*	OVERLAP E32 E33 E34 E35 E36 E43 E42 E44 E46 E47 E49 E50 E51 E52 E53 E54 E55 E56 E57 E59 E60 E61 E62 E63 E64 E65 E66 E67 E68 E69 E71 E72 E74 E75
+R69	BEFORE Arg1:E75 Arg2:E78	
+R70	AFTER Arg1:E78 Arg2:E77	
+R71	BEFORE Arg1:E77 Arg2:E80	
+*	OVERLAP E80 E81