Patients must be willing to provide prior smoking history as required on the S Onstudy Form
No active tobacco use (>  years tobacco free interval, <  pack/year [pk/yr.] history)
Noncompliance - inability or unwillingness to comply with medical recommendations regarding therapy or follow-up, including smoking tobacco. Smoking cessation is a standard teaching practice prior to admission for all patients undergoing stem cell transplant. Any patient who refuses to stop smoking prior to transplant will not be eligible for this study.
Lifetime pack-year history of <  years, currently non-smoking for at least  years.
Patients must provide their personal smoking history prior to registration; patients cannot have a cumulative personal smoking history that exceeds  pack-years\r\n* Number of pack-years = (frequency of smoking [number of cigarettes per day] x duration of cigarette smoking [years]) / \r\n* Note: Twenty cigarettes is considered equivalent to one pack; cigar and pipe tobacco consumption is not included in calculating lifetime pack-years
History of smoking tobacco (or other related/herbal products) in the prior  months
Active smoking or a cumulative pack year history of >  pack years, active smoking is (defined as >=  cigarette per day) within the last  years
Actively smoking  or more cigarettes per day for at least one year
Smoking  or more cigarettes, little cigars and/or cigarillos per day, on average, within the  months preceding the screening visit and expired carbon monoxide (CO) greater than or equal to  parts per million (ppm) (if less than or equal to , then NicAlert Strip > )
>  pack years of tobacco use or more
Less than or equal to  pack years of tobacco history
Patients registering to Arms D, E, F, G, H, I, X, Y must not currently be smoking tobacco or other substances and must not have smoked within the past  months
Patients who have a smoking history of >  pack-years
Patients who have never smoked, defined as smoking ? cigarettes in a lifetime
Intermediate-risk group: Oropharynx cancer that is p-positive by immunohistochemistry with smoking status >  Pack-years, stage T-Nb-N OR ?  pack-years, stage TN-N or T-N.
History of smoking either tobacco or other herbal products in the last  months
Patients must provide their personal smoking history prior to registration; the lifetime cumulative history cannot exceed  pack-years; the following formula is used to calculate the pack-years during the periods of smoking in the patients life; the cumulative total of the number of pack-years during each period of active smoking is the lifetime cumulative history\r\n* Number of pack-years = (frequency of smoking [number of cigarettes per day] x duration of cigarette smoking [years])/ \r\n* Note: twenty cigarettes is considered equivalent to one pack; the effect of non-cigarette tobacco products on the survival of patients with p-positive oropharyngeal cancers is undefined; cigar and pipe tobacco consumption is therefore not included in calculating the lifetime pack-years; marijuana consumption is likewise not considered in this calculation; there is no clear scientific evidence regarding the role of chewing tobacco-containing products in this disease; investigators are discouraged from enrolling patients with a history of very sustained use (such as several years or more) of non-cigarette tobacco products alone
History of >=  pack-years of smoking cigarettes
Smoking history <  pack-year or equivalent (including cigarettes, cigars, pipes, chewing tobacco, and/or marijuana); one cannabis joint is equivalent of  cigarettes; smoking status definitions (National Health Interview Survey and Behavioral Risk Factor Surveillance System):\r\n* Smokers: smoking now every day or some days in past month\r\n* Quitters: at least  cigarettes/lifetime and not smoking in the past - months\r\n* Former smoker: at least  cigarettes/lifetime and not smoking >  months\r\n* Never smokers: <  cigarettes (or equivalent)/lifetime
For NSCLC, patients must have a minimum of a  pack-year smoking history.
Patients smoking in excess of  packs of cigarettes per day
Having at least a -pack year history of cigarette smoking
Patients with oropharynx carcinoma with a smoking history of ?  pack-year or equivalent  year history of tobacco product use and no recent history (within last  years) of tobacco use
Smoking history <  pack years or equivalent  year history of tobacco product use
Active smoking within the past  years with a cumulative pack year history of >  pack years or active smoking (defined as >=  cigarette per day) within the last  years
Patients with >  pack years of smoking history and/or currently a smoker at the time of treatment
Patients with smoking history of less than or equal to  pack years and with primary tumour site of base of tongue and/or tonsil
Patients with no smoking history
Desire to quit smoking, with at least one prior failed quit attempt and willingness to participate in a treatment study
Motivated to stop smoking, as indicated by a score of  or above on the Contemplation Ladder
Individuals who use e-cigarettes and who are not smoking cigarettes; dual users (those who use both e-cigarettes and cigarettes) will be included in the trial
Patient is a current or ex-smoker with a smoking history of >=  pack years
Subject is a current smoker, or has smoked within  months prior to enrollment, or plans to resume smoking within  months post-enrollment
Do not smoke (no smoking during previous  months)
History of previous experience with smoking or marijuana
Participants must not be active smokers within the past  days; active smoking is defined as any smoking, even a puff; if identified as a smoker, the individual will be referred the New York (NY) State Smoking Cessation Quit line (nysmokefree.com) which is available in English and Spanish
Smoking history of  pack-years or greater
Smoking
Documentation of current smoking in the cancer registry
Current smoker or quit smoking within the past  years
At least a  pack-year smoking history
=<  pack-years smoking history or =<  pack-years smoking history WITH >=  years abstinence from smoking
Patients who have smoked within the last  months, since smoking may interfere with relaxation and breathing
Not smoking
Willing to discontinue smoking for the duration of study intervention
Have at least a  pack-year history of smoking
Current tobacco smokers with >=  pack years of self-reported smoking exposure and an average use of >=  cigarettes/day
Urine cotinine level, if collected at screening, does not confirm active smoking status
Smoking history of >=  pack?years AND either current smoker (still smoking or quit <  year prior to pre?registration) OR former smoker (quit ? years prior to pre?registration); Note: Pack years is determined by multiplying the number of packs smoked per day by the number of years smoked
Smoking for at least one year
Carbon monoxide (CO) level of  ppm or greater, confirming smoking status
Involvement in a smoking program or currently trying to quit.
Current tobacco smokers with >=  pack years of self-reported smoking exposure and a current average use of >=  cigarettes/day
Willing to complete all appointments and change smoking behaviors for -weeks
 pack year history of smoking (i.e., the base population of high risk smokers to get screened)
Current smoker (defined as any smoking in the past  days  this is the criteria our lung cancer screening programs will use to trigger tobacco treatment interventions)
Smoking >=  tobacco cigarettes/week over the past year
Insufficient smoking (<  cigs per week) or have recently quit
Current motivation to quit smoking
Daily smoker for ?  months, smoking approximately ?  cigarettes per day on average in the past month or must meet the criteria for nicotine dependence
Smoking  or more cigarettes, little cigars or cigarillos per day, on average, within the  months preceding the screening visit and expired carbon monoxide (CO) greater than or equal to  parts per million (ppm); (if < , then NicAlert Strip > )
>=  year history of smoking, and smoking >=  cigarettes per week
Patients who chew tobacco and patients who are not smoking but are exposed to second hand smoking are excluded from this study
Be either a current smoker or a never smoker; to define a smoker, we will utilize the Centers for Disease Control definitions; any individual who is currently smoking and has smoked more than  cigarettes in their lifetime will be identified as a current smoker; smoking status will be assessed by a questionnaire; smoking status will be conferred using a urine cotinine test at the randomization visit (week-); the number of cigarettes smoked per day and years of smoking will be used to calculate pack-years, which will be used as a measure of tobacco exposure; a never smoker is defined as a person who has never smoked, or has smoked less than  cigarettes in their lifetime, and who has not had a cigarette in over ten years
Resides in a smoking household (where  or more household members smoke)
Active smoking (cigarettes per day [CPD] >= ) and exhaled carbon monoxide (CO) >=  parts per million (ppm)
Participants will include current and recently quit former smokers who have at least a  pack year smoking history (defined by number of packs smoked per day multiplied by number of years smoked)
Participants must have a smoking history of  pack-years or greater
All participants must also report an intention to quit smoking within the next month and a desire to receive behavioral and medication treatment.
Participation in a smoking study in the past  months.
Additionally, prior to enrollment at first session, reporting smoking  or more days of the past , or registering a carbon monoxide (CO) reading of  or above (as this indicates heavy smoking, and is not consistent with non-daily smoking.)
Smoking  or more cigarettes, little cigars or cigarillos per day, on average, within the  months preceding the screening visit and expired carbon monoxide (CO) greater than or equal to  parts per million (ppm) (if =< , then NicAlert strip > )
Not currently participating in a quit smoking program
Willingness to abstain from smoking for  hours (overnight abstinence) prior to study visits
Reside in a facility that does not allow smoking (e.g. certain nursing homes)
For smoking cessation groups, unwillingness to participate or no desire to quit smoking
PHASE I: Individuals at risk for lung cancer based on a smoking history of  or more pack/years of cigarette smoking
PHASE II: Smoking history of  or more pack/years of cigarette smoking
STUDY I: Current dual users (of tobacco cigarettes and e-cigarettes) without interest in quitting smoking
STUDY I: Current dual users who have attempted, but not quit smoking
STUDY I: >=  year history of weekly smoking
Nonsmokers (not smoking during previous  months)
Smoking history >=  pack/years; subjects must be included in an ongoing annual screening with low dose CT scan or must have two consecutive CT outside the context of a screening program confirming subsolid nodules
A current or ex-smoker with a >=  pack-year history of smoking; (an ex-smoker is defined as no tobacco use in the prior  months)
Motivated to quit smoking
Currently smoking  or more cigarettes per day
Male or female current tobacco smokers with >=  pack years of self-reported smoking exposure and an average use of >=  cigarettes/day
Urine cotinine level, if collected at screening, does not confirm active smoking status
Inclusion Criteria (adult):\n\n          -  Age  years or older\n\n          -  Female\n\n          -  Smoked ?  cigarettes per day for at least the past  months\n\n          -  Smoked on  days or more in the last month\n\n          -  Smoking status confirmed via cotinine verification strips\n\n          -  Resides with a child ?  years of age in the role of the child's parent or caregiver\n\n          -  Will agree to provide a urine sample at study enrollment\n\n          -  Will also agree to the child providing a urine sample at study enrollment and at\n             follow-up visits (for children who are not toilet trained, a diaper sample will be\n             collected in lieu of the urine sample)\n\n          -  Has a home address\n\n          -  Has a functioning home phone or cell phone\n\n          -  Provides written informed consent\n\n        Inclusion criteria (child):\n\n          -  < or =  years of age\n\n          -  Non-smoker -no cigarette use within prior  days to enrollment; however\n             experimentation with smoking (a puff) will not exclude the child\n\n          -  Lives in the primary home with the adult study participant at least  days a week\n\n        Exclusion criteria (adult):\n\n          -  Current or past  day use of Nicotine Replacement Therapy (NRT) or pharmacotherapy for\n             smoking cessation\n\n          -  Planning to move outside of Minnesota within the next  months\n\n          -  Have complete home smoking restrictions currently in place verified by the nicotine\n             dosimeter\n\n          -  Currently pregnant
Inclusion criteria:\n\n        Initial from phone interview:\n\n          -  Currently smoking - cigarettes per day for the past year;\n\n          -  Between the ages of  and  years;\n\n          -  In apparently good physical health with no unstable medical conditions including\n             seizures or cancer;\n\n          -  In stable and good mental health, i.e., currently do not experience unstable or\n             untreated psychiatric diagnosis, including substance abuse, as determined by the\n             DSM-IV criteria, during the past six months;\n\n          -  Not using any other tobacco or nicotine-containing products;\n\n          -  Not on methadone maintenance or stimulants such as ephedra; not a regular user of\n             street drugs and if uses occasionally, willing to abstain during the study; not taking\n             any drugs known to be PA substrates such as phenobarbital, rifampicin,\n             dexamethasone, ketoconazole, methoxsalen, pilocarpine, or tranylcypromine due to their\n             role in NNK metabolism;\n\n          -  Does not average more than  alcoholic drinks per week;\n\n          -  Willing to perform study activities such as having blood sample drawn, urine\n             collection, multiple clinic visits;\n\n          -  For female subjects of child bearing potential, not known to be pregnant or nursing,\n             or planning to become pregnant within next  months.\n\n        For enrollment in the Short-Term Trial:\n\n          -  Subjects who are generally healthy with liver enzyme and blood count values within the\n             ranges shown below based on blood samples drawn at the second screening visit.\n             Specifically:\n\n               -  White blood cells ? ,/mL\n\n               -  Total bilirubin ? . x upper limits of normal (ULN)\n\n               -  AST (SGOT)/ALT (SGPT) ? . x ULN\n\n               -  BUN and serum creatinine ? . x ULN\n\n        For enrollment in the Long-Term Trial:\n\n          -  Participated in the short-term trial and invited to participate in the long-term\n             trial;\n\n          -  Possess the GSTM null-null genotype;\n\n          -  Smoke  or more cigarettes/day with a cumulative smoking history of  or more\n             pack-years (one pack-year equals to smoking a pack of cigarettes a day for one year);\n\n          -  Normal liver enzymes based on blood sample drawn during  month wash-out;\n\n          -  Determined to be a good candidate for the bronchoscopy procedure by a primary care\n             physician.\n\n        Exclusion Criteria:\n\n          -  Subjects with uncontrolled hypertension, uncontrolled diabetes mellitus, unstable\n             coronary artery disease, history of cancer other than non-melanoma skin cancer, and\n             pregnant or lactating women will not be eligible.
Subjects with a smoking history of at least  cigarettes daily for at least  year (carbon monoxide [CO] >  parts per million (ppm); if CO =<  ppm, then Nic Alert test =< level ) and no serious quit attempts in the last  months (to ensure stability of smoking)
Patient smoking status will be documented in their electronic health record, per routine care
Have at least a -pack year smoking history (average packs per day x years smoking)
Smoking cigarettes for at least  years (so that smoking is expected to be reasonably established)
Smoking non-daily for the previous one year
Willingness and ability to come to the University of Pittsburghs Smoking Research Group lab for  visits over a -week period, and to report on smoking behavior via an IVR telephone system during that time
Exclusive use of roll-your-own cigarettes (since the study uses manufactured cigarettes); and cannot be currently smoking more than / of roll your own cigarettes
At first session, reporting smoking  or more days of the past , or registering a carbon monoxide (CO) reading of  or above
at least some concern for health effects of smoking