Patients must have a Lansky or Karnofsky performance status score of >= , corresponding to Eastern Cooperative Oncology Group (ECOG) categories ,  or ; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age \r\n* Note: Neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age \r\n* Note: Neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: Neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; note: neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; NOTE: neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a Lansky or Karnofsky performance status score of >= , corresponding to Eastern Cooperative Oncology Group (ECOG) categories ,  or ; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age\r\n* Note: Neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: Neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age\r\n* Note: Neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a performance status corresponding to Eastern Cooperative Oncology Group (ECOG) scores of , , or ; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >= % for patients =<  years of age; Note: Neurologic deficits in patients with metastatic CNS tumors must have been relatively stable for a minimum of  week prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for subjects >  years of age and Lansky >=  for subjects =<  years of age; Note: subjects who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Lansky >=  for patients =<  years of age or as per institutional guidelines; Note: Patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky performance status >= % for patients >  years of age and Lansky >=  for patients =< years of age; Note: neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patient must have a Karnofsky (if >=  years of age) or Lansky performance score (if =<  years of age) of >=  by the time of registration; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >=  for patients >=  years of age, and Lansky >=  for patients <  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky performance scale (KPS for >  years of age) or Lansky performance score (LPS for =<  years of age) assessed within two weeks of enrollment must be >= ; patients who are unable to walk because of neurologic deficits, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
INCLUSION CRITERIA FOR STRATUM C: Karnofsky performance scale (KPS for >  years of age) or Lansky performance score (LPS for =<  years of age) assessed within two weeks of enrollment must be >= ; patients who are unable to walk because of neurologic deficits, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients >=  years of age: Karnofsky >= %; patients =<  years of age: Lansky scale >= %; subjects who are unable to walk because of paralysis, but who are upright in a wheelchair will be considered ambulatory for the purpose of calculating the performance score
Karnofsky (>  years of age) or Lansky (=<  years of age) performance status (PS) %; Note: patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >=  for patients >  years of age and Lansky >=  for patients =<  years of age. Patients who are unable to walk because of paralysis, but who are able to mobilize using a wheelchair, will be considered ambulatory for the purpose of assessing the performance score.
Clinical performance status: Patients >  years of age: Karnofsky ? %; patients <  years of age: Lansky scale ? %; subjects who are unable to walk because of paralysis, but who are upright in a wheelchair will be considered ambulatory for the purpose of calculating the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: Neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky > % for patients >  years of age and Lansky > % for patients <  years of age; neurologic deficits in patients with central nervous system (CNS) tumors must have been relatively stable for a minimum of  days; patients who are unable to walk because of paralysis, but who are able to sit in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a Karnofsky >= % for subjects >  years of age and Lansky score >=  for subjects =<  years of age \r\n* Note: Subjects who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Participant's performance score must be ?% Karnofsky (for participants > years of age) or Lansky (for participants less than or equal to (?) years of age).Participants who are unable to walk because of paralysis and/or previous surgeries, but who are in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score.
Karnofsky >=  for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age\r\n* Note: Neurologic deficits in patients must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a performance status corresponding to Karnofsky or Lansky greater than or equal to %; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a performance status corresponding to Karnofsky or Lansky greater than or equal to %; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Performance status defined by Karnofsky or Lansky >=  (except for patients with posterior fossa syndrome); use Karnofsky for patients >=  years and Lansky for patients <  years; note: patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered to be ambulatory for the purpose of assessing the performance score
At the time of study enrollment patients must have a Karnofsky greater than or equal to % for patients >  years of age and Lansky greater than or equal to  for patients less than or equal to  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for subjects >  years of age and Lansky >=  for subjects =<  years of age; note: subjects who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Performance level: Karnofsky > or equal to % for patients >  years of age or Lansky > or equal to  for patients <  years of age; Note: patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Lansky score of  or greater if =< years of age or a Karnofsky score of  or greater if >  years of age (NOTE: patients who are unable to walk because of paralysis, but who are in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score)
Karnofsky performance scale (KPS for >  years of age) or Lansky performance score (LPS for =<  years of age) assessed within two weeks of enrollment must be >= ; patients who are unable to walk because of neurologic deficits, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a performance status of >=  by Lansky or Karnofsky, corresponding to Eastern Cooperative Oncology Group (ECOG) scores of , , or . Use Karnofsky for patients >  years of age and Lansky for patients =<  years of age. Patients who are unable to walk because of paralysis, but are up in a wheelchair will be considered ambulatory for the purposes of assessing the performance score
Karnofsky ?  for subjects >  years of age and Lansky ?  for subjects ?  years of age \r\n* Note: subjects who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: Neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky performance scale (KPS for >  years of age) or Lansky performance score (LPS for =<  years of age) assessed within two weeks of enrollment must be >= ; patients who are unable to walk because of neurologic deficits, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >=  for patients >=  years of age, and Lansky >=  for patients <  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score; patients with pre-existing neurological deficits need to be stable prior to surgery or lumbar puncture (LP) as determined by the investigator
Patients must have a performance status corresponding to Eastern Cooperative Oncology Group (ECOG) scores of , , or ; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a performance status corresponding to an Eastern Cooperative Oncology Group (ECOG) scores of ,  or ; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; Note: patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patients must have a Lansky or Karnofsky performance status score of >= , corresponding to Eastern Cooperative Oncology Group (ECOG) categories ,  or ; use Karnofsky for patients >  years of age and Lansky for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: neurologic deficits in patients with CNS tumors must have been relatively stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; Note: patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Clinical performance status: patients >  years of age: Karnofsky >= %; patients =<  years of age: Lansky scale >= %; subjects who are unable to walk because of paralysis, but who are upright in a wheelchair will be considered ambulatory for the purpose of calculating the performance score
Performance level: Karnofsky >=  for patients >  years of age and Lansky >=  for patients =<  years of age); Note: patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Performance Status  Karnofsky >  % for patients > years of age or Lansky >  for patients <  years of age. Patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score.
Patients must have Karnofsky performance score (for patients >  years of age) or Lansky performance score (for patients =<  years of age) >= % assessed within two weeks of study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky score >=  for patients >=  years of age and Lansky score >=  for patients =<  years of age; patients who are unable to walk because of paralysis but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >= % for patients =<  years of age; neurologic deficits in patients with central nervous system (CNS) tumors must have been relatively stable for a minimum of  days; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky performance score ? for participants> year of age and Lansky play score ? for participants ? years of age. Neurologic deficits in participants with CNS tumors must have been relatively stable for at least  days prior to study enrollment. Participants who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
RECURRENT/ PROGRESSIVE DIPG (STRATUM ): Karnofsky performance scale (KPS for >  years of age) or Lansky performance score (LPS for =<  years of age) assessed within  days of enrollment must be >= %; patients who are unable to walk because of neurologic deficits, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
NON-PROGRESSED DIPG (STRATUM ): Karnofsky performance scale (KPS for >  years of age) or Lansky performance score (LPS for =<  years of age) assessed within  days of enrollment must be >= %; patients who are unable to walk because of neurologic deficits, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; note: neurologic deficits in patients with central nervous system (CNS) tumors must have been relatively stable for a minimum of  week prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Karnofsky >= % for patients >  years of age or Lansky >= % for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Performance Status: Karnofsky >= % for >  years of age; Lansky >= % for children =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purposes of assessing performance score
Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
ELIGIBILITY CRITERIA FOR ENROLLMENT ONTO APECSC: Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age); Note: neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
GENERAL INCLUSION CRITERIA FOR SUBPROTOCOLS: Karnofsky >= % for patients >  years of age and Lansky >=  for patients =<  years of age); Note: neurologic deficits in patients with CNS tumors must have been stable for at least  days prior to study enrollment; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score
Patient must have a Lansky or Karnofsky performance of > % corresponding to Eastern Cooperative Oncology Group (ECOG) categories , , or ; Karnofsky will be used for patients >  years of age and Lansky for patients <  years of age; patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score