| 1 |
29311820 |
10.3389/fnmol.2017.00432 |
2022 |
Activation of Autophagy Contributes to Sevoflurane-Induced Neurotoxicity in Fetal Rats. |
PTEN |
| 2 |
29594222 |
10.1016/j.ctro.2017.09.006 |
2022 |
The impact of the IGF-1 system of cancer cells on radiation response - An <i>in vitro</i> study. |
PTEN |
| 3 |
31572063 |
10.1186/s12935-019-0960-5 |
2022 |
Ethanol extract of <i>Ligustrum lucidum Ait.</i> leaves suppressed hepatocellular carcinoma in vitro and in vivo. |
PTEN |
| 4 |
32393046 |
10.1080/09603123.2020.1757043 |
2022 |
The expression of microRNAs and exposure to environmental contaminants related to human health: a review. |
PTEN |
| 5 |
32431543 |
10.2147/CMAR.S242903 |
2022 |
Clinicopathological Characteristics and Mutational Profiling of Adult T-Cell Lymphoblastic Lymphoma in a Chinese Population. |
PTEN |
| 6 |
32606772 |
10.2147/OTT.S250233 |
2022 |
HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice. |
PTEN |
| 7 |
33404293 |
10.1080/15548627.2020.1871204 |
2022 |
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes. |
PTEN |
| 8 |
33458694 |
10.1158/2643-3230.BCD-20-0201 |
2022 |
A Tumor Suppressor Enhancer of <i>PTEN</i> in T-cell development and leukemia. |
PTEN |
| 9 |
34046322 |
|
2022 |
Cytotoxic effects of hydroalcoholic extract of <i>Cuscuta chinensis</i> on PC3 and MCF7 cancer cell lines. |
PTEN |
| 10 |
34217275 |
10.1186/s12920-021-01023-9 |
2022 |
Hypodiploidy in a pediatric patient of T-cell acute lymphoblastic leukemia: a case report. |
PTEN |
| 11 |
34396903 |
10.1080/10428194.2021.1965139 |
2022 |
Response to everolimus in a patient with refractory HGBL-NOS harboring multiple genomic aberrations in PTEN. |
PTEN |
| 12 |
34669944 |
10.1093/mtomcs/mfab058 |
2022 |
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice. |
PTEN |
| 13 |
34708625 |
10.19852/j.cnki.jtcm.2021.05.003 |
2022 |
Mechanism of total glucosides from Chishao (Radix Paeoniae Rubra) on proliferation and apoptosis of hepatocellular carcinoma cells via phosphatase and tensin homolog deleted on chromosome ten / phosphatidylinositol 3-kinase / protein kinase B signaling pathway. |
PTEN |
| 14 |
34750354 |
10.1038/s41419-021-04353-9 |
2022 |
Cooperative miRNA-dependent PTEN regulation drives resistance to BTK inhibition in B-cell lymphoid malignancies. |
PTEN |
| 15 |
34814054 |
10.1016/j.tice.2021.101674 |
2022 |
Mechanism of IDH1-R132H mutation in T cell acute lymphoblastic leukemia mouse model via the Notch1 pathway. |
PTEN |
| 16 |
34831026 |
10.3390/cells10112803 |
2022 |
Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL. |
PTEN |
| 17 |
34837676 |
10.22074/cellj.2021.7302 |
2022 |
AntagomiR-19a Induced Better Responsiveness to Bortezomib in Myeloma Cell Lines. |
PTEN |
| 18 |
34956421 |
10.1155/2021/9956666 |
2022 |
miRNA-19b-3p Stimulates Cardiomyocyte Apoptosis Induced by Myocardial Ischemia Reperfusion via Downregulating PTEN. |
PTEN |
| 19 |
35068334 |
10.1080/21655979.2022.2026552 |
2022 |
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells. |
PTEN |
| 20 |
35072573 |
10.1177/15330338211070689 |
2022 |
Roles of BMI1 in the Initiation, Progression, and Treatment of Hepatocellular Carcinoma. |
PTEN |
| 21 |
35116342 |
10.21037/tcr-21-2394 |
2022 |
miRNA-425-5p enhances diffuse large B cell lymphoma growth by targeting PTEN. |
PTEN |
| 22 |
35117001 |
10.21037/tcr.2019.10.04 |
2022 |
Prognostic relevance of genetic variations in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma. |
PTEN |
| 23 |
35117766 |
10.21037/tcr-20-2071 |
2022 |
The expression of SOX9, Tiam1, and PTEN is correlated with angiogenesis and prognosis in gastric cancer. |
PTEN |
| 24 |
35133871 |
10.1200/JCO.21.01648 |
2022 |
Phase II Study of Copanlisib in Patients With Tumors With <i>PIK3CA</i> Mutations: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1F. |
PTEN |
| 25 |
35138919 |
10.1200/PO.21.00424 |
2022 |
Phase II Study of Taselisib in <i>PIK3CA</i>-Mutated Solid Tumors Other Than Breast and Squamous Lung Cancer: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol I. |
PTEN |
| 26 |
35142981 |
10.1007/s11033-022-07203-9 |
2022 |
Apoptosis induction in human lung and colon cancer cells via impeding VEGF signaling pathways. |
PTEN |
| 27 |
35184749 |
10.1186/s12885-022-09275-z |
2022 |
The PI3K/AKT/mTOR signaling pathway is aberrantly activated in primary central nervous system lymphoma and correlated with a poor prognosis. |
PTEN |
| 28 |
35185889 |
10.3389/fimmu.2022.797244 |
2022 |
Calcium Signaling Is Impaired in PTEN-Deficient T Cell Acute Lymphoblastic Leukemia. |
PTEN |
| 29 |
35231988 |
10.3760/cma.j.issn.0253-2727.2022.01.005 |
2022 |
[Mutational spectrum and its prognostic significance in childhood acute lymphoblastic leukemia based on next-generation sequencing technology]. |
PTEN |
| 30 |
35253299 |
10.1002/gcc.23036 |
2022 |
CRLF2 overexpression defines an immature-like subgroup which is rescued through restoration of the PRC2 function in T-cell precursor acute lymphoblastic leukemia. |
PTEN |
| 31 |
35260738 |
10.1038/s41598-022-08049-8 |
2022 |
PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to L-asparaginase. |
PTEN |
| 32 |
35279479 |
10.1016/j.imbio.2022.152205 |
2022 |
Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia. |
PTEN |
| 33 |
35336821 |
10.3390/biology11030449 |
2022 |
Post-Irradiation Thymic Regeneration in B6C3F1 Mice Is Age Dependent and Modulated by Activation of the PI3K-AKT-mTOR Pathway. |
PTEN |
| 34 |
35411248 |
|
2022 |
PIK-75 overcomes venetoclax resistance <i>via</i> blocking PI3K-AKT signaling and MCL-1 expression in mantle cell lymphoma. |
PTEN |
| 35 |
35456022 |
10.3390/cells11081343 |
2022 |
Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H<sub>2</sub>AX, CHK2 and p53. |
PTEN |
| 36 |
35503721 |
10.7554/eLife.69255 |
2022 |
The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress. |
PTEN |
| 37 |
35563843 |
10.3390/cells11091537 |
2022 |
Signal Transduction Regulators in Axonal Regeneration. |
PTEN |
| 38 |
35592654 |
10.1155/2022/5707504 |
2022 |
Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch. |
PTEN |
| 39 |
35616841 |
10.1007/s11356-022-20734-9 |
2022 |
Cadmium induces apoptosis by miR-9-5p targeting PTEN and regulates the PI3K/AKT pathway in the piglet adrenal gland. |
PTEN |
| 40 |
35687490 |
10.1182/bloodadvances.2021006654 |
2022 |
Genomic characterization of lymphomas in patients with inborn errors of immunity. |
PTEN |
| 41 |
35869735 |
10.14715/cmb/2022.68.2.14 |
2022 |
Influences of ALDH2 on Cardiomyocyte Apoptosis in Heart Failure Rats Through Regulating PINK1-Parkin Signaling Pathway-Mediated Mitophagy. |
PTEN |
| 42 |
35905946 |
10.1016/j.tox.2022.153275 |
2022 |
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells. |
PTEN |
| 43 |
35910796 |
10.7150/thno.72786 |
2022 |
Inhibition of acylglycerol kinase sensitizes DLBCL to venetoclax via upregulation of FOXO1-mediated BCL-2 expression. |
PTEN |
| 44 |
30216493 |
10.1002/jcb.27081 |
2021 |
Upregulated microRNA-132 rescues cardiac fibrosis and restores cardiocyte proliferation in dilated cardiomyopathy through the phosphatase and tensin homolog-mediated PI3K/Akt signal transduction pathway. |
PTEN |
| 45 |
30304554 |
10.1002/jcb.27559 |
2021 |
Effects of microRNA-494 on proliferation, migration, invasion, and apoptosis of medulloblastoma cells by mediating c-myc through the p38 MAPK signaling pathway. |
PTEN |
| 46 |
31682844 |
10.1016/j.jid.2019.08.454 |
2021 |
Preclinical Evidence for Targeting PI3K/mTOR Signaling with Dual-Inhibitors as a Therapeutic Strategy against Cutaneous T-Cell Lymphoma. |
PTEN |
| 47 |
31712222 |
10.1101/cshperspect.a036244 |
2021 |
PTEN in Regulating Hematopoiesis and Leukemogenesis. |
PTEN |
| 48 |
31744878 |
10.1158/1541-7786.MCR-19-0217 |
2021 |
HSF1-Mediated Control of Cellular Energy Metabolism and mTORC1 Activation Drive Acute T-Cell Lymphoblastic Leukemia Progression. |
PTEN |
| 49 |
31752573 |
10.1080/10428194.2019.1691200 |
2021 |
New murine models of aggressive lymphoma. |
PTEN |
| 50 |
31804006 |
10.1002/cam4.2757 |
2021 |
RAS and TP53 can predict survival in adults with T-cell lymphoblastic leukemia treated with hyper-CVAD. |
PTEN |
| 51 |
31863623 |
10.1111/jcmm.14782 |
2021 |
Relationship between polycomb-group protein BMI-1 and phosphatases regulating AKT phosphorylation level in endometrial cancer. |
PTEN |
| 52 |
32004387 |
10.1111/bjh.16435 |
2021 |
Evaluation of the PIK3 pathway in peripheral T-cell lymphoma and NK/T-cell lymphoma. |
PTEN |
| 53 |
32020591 |
10.1002/jcp.29544 |
2021 |
Long noncoding RNA TCL6 binds to miR-106a-5p to regulate hepatocellular carcinoma cells through PI3K/AKT signaling pathway. |
PTEN |
| 54 |
32062191 |
10.1016/j.ceca.2020.102171 |
2021 |
Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca<sup>2+</sup>-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. |
PTEN |
| 55 |
32134755 |
10.1097/PAI.0000000000000839 |
2021 |
PTEN Loss and Cyclin A2 Upregulation Define a PI3K/AKT Pathway Activation in Helicobacter pylori-induced MALT and DLBCL Gastric Lymphoma With Features of MALT. |
PTEN |
| 56 |
32142900 |
10.1016/j.jmoldx.2020.02.004 |
2021 |
Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia. |
PTEN |
| 57 |
32329824 |
10.26355/eurrev_202004_20810 |
2021 |
Effects of miR-32 targeting PTEN on proliferation and apoptosis of myeloma cells. |
PTEN |
| 58 |
32374309 |
10.1039/d0fo00019a |
2021 |
Dietary supplementation of l-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction. |
PTEN |
| 59 |
32380791 |
10.3390/cells9051137 |
2021 |
hsa-miR-20b-5p and hsa-miR-363-3p Affect Expression of <i>PTEN</i> and <i>BIM</i> Tumor Suppressor Genes and Modulate Survival of T-ALL Cells In Vitro. |
PTEN |
| 60 |
32423803 |
10.1016/j.bbrc.2020.03.165 |
2021 |
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis. |
PTEN |
| 61 |
32479694 |
10.1002/cyto.b.21882 |
2021 |
Single-cell profiling of pediatric T-cell acute lymphoblastic leukemia: Impact of PTEN exon 7 mutation on PI3K/Akt and JAK-STAT signaling pathways. |
PTEN |
| 62 |
32483710 |
10.1134/S0012496620020106 |
2021 |
Changes in the Activity of Genes Involved in the Regulation of Hematopoiesis during Tumorigenesis in Irradiated Mice. |
PTEN |
| 63 |
32495857 |
10.26355/eurrev_202005_21306 |
2021 |
LncRNA MEG3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating PTEN. |
PTEN |
| 64 |
32812017 |
10.1182/blood.2020006996 |
2021 |
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia. |
PTEN |
| 65 |
32970929 |
10.1111/ajco.13449 |
2021 |
Role and mechanism of autophagy-regulating factors in tumorigenesis and drug resistance. |
PTEN |
| 66 |
33000212 |
10.3892/or.2020.7776 |
2021 |
SPAG6 promotes cell proliferation and inhibits apoptosis through the PTEN/PI3K/AKT pathway in Burkitt lymphoma. |
PTEN |
| 67 |
33037136 |
10.1158/1535-7163.MCT-19-0973 |
2021 |
Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A. |
PTEN |
| 68 |
33054126 |
10.3324/haematol.2020.262659 |
2021 |
<i>CDKN2A</i> deletion is a frequent event associated with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified (PTCL-NOS). |
PTEN |
| 69 |
33082322 |
10.1038/s41419-020-03098-1 |
2021 |
Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome. |
PTEN |
| 70 |
33085743 |
10.1093/abbs/gmaa100 |
2021 |
NO66 overexpression rescues ethanol-induced cell apoptosis in human AC16 cardiomyocytes by suppressing PTEN and activating the PI3K/Akt signaling. |
PTEN |
| 71 |
33128318 |
10.1111/cas.14716 |
2021 |
Pathophysiological significance of N-myc downstream-regulated gene 2 in cancer development through protein phosphatase 2A phosphorylation regulation. |
PTEN |
| 72 |
33154951 |
10.3389/fonc.2020.591577 |
2021 |
Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies. |
PTEN |
| 73 |
33179084 |
10.3892/mmr.2020.11666 |
2021 |
Effects and mechanism of microRNA‑218 against lung cancer. |
PTEN |
| 74 |
33191568 |
10.1002/onco.13595 |
2021 |
More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment. |
PTEN |
| 75 |
33436855 |
10.1038/s41598-020-80613-6 |
2021 |
Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia. |
PTEN |
| 76 |
33515421 |
10.1007/s12094-020-02520-6 |
2021 |
Downregulation of HOXA11 enhances endometrial cancer malignancy and cisplatin resistance via activating PTEN/AKT signaling pathway. |
PTEN |
| 77 |
33561953 |
10.3390/cancers13040650 |
2021 |
Spatial Heterogeneity in Large Resected Diffuse Large B-Cell Lymphoma Bulks Analysed by Massively Parallel Sequencing of Multiple Synchronous Biopsies. |
PTEN |
| 78 |
33634864 |
10.1002/ijc.33527 |
2021 |
Deleterious point mutations in T-cell acute lymphoblastic leukemia: Mechanistic insights into leukemogenesis. |
PTEN |
| 79 |
33651821 |
10.1371/journal.pone.0247394 |
2021 |
IL-6 promotes MYC-induced B cell lymphomagenesis independent of STAT3. |
PTEN |
| 80 |
33724154 |
10.1080/21505594.2021.1899674 |
2021 |
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage. |
PTEN |
| 81 |
33790574 |
10.2147/OTT.S189032 |
2021 |
Oral PI3K-δ,γ Inhibitor for the Management of People with Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: A Narrative Review on Duvelisib. |
PTEN |
| 82 |
33813280 |
10.1016/j.bbrc.2021.03.081 |
2021 |
Nuclear PTEN deficiency and heterozygous PTEN loss have distinct impacts on brain and lymph node size. |
PTEN |
| 83 |
33843428 |
10.1080/10428194.2021.1913148 |
2021 |
SPAG6-silencing enhances decitabine-induced apoptosis and demethylation of PTEN in SKM-1 cells and in a xenograft mouse model. |
PTEN |
| 84 |
33898103 |
10.1016/j.omtn.2021.03.011 |
2021 |
Cell death pathways and viruses: Role of microRNAs. |
PTEN |
| 85 |
33941203 |
10.1186/s13045-021-01068-4 |
2021 |
Oncogenetic landscape and clinical impact of IDH1 and IDH2 mutations in T-ALL. |
PTEN |
| 86 |
33966404 |
10.21037/apm-21-604 |
2021 |
microRNA-181a promotes the proliferation of hypertrophic scar fibroblasts and inhibits their apoptosis via targeting phosphatase and tensin homolog. |
PTEN |
| 87 |
34061780 |
10.1172/JCI146893 |
2021 |
TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies. |
PTEN |
| 88 |
34118770 |
10.1016/j.esmoop.2021.100187 |
2021 |
Clinical benefits of precision medicine in treating solid cancers: European Society of Medical Oncology-Magnitude of Clinical Benefit Scale score-based analysis. |
PTEN |
| 89 |
34166762 |
10.1016/j.neuroscience.2021.06.021 |
2021 |
Phosphatase and Tensin Homolog Deleted on Chromosome Ten Knockdown Attenuates Cognitive Deficits by Inhibiting Neuroinflammation in a Mouse Model of Perioperative Neurocognitive Disorder. |
PTEN |
| 90 |
34488159 |
10.1016/j.envpol.2021.118036 |
2021 |
Quercetin antagonizes imidacloprid-induced mitochondrial apoptosis through PTEN/PI3K/AKT in grass carp hepatocytes. |
PTEN |
| 91 |
34589395 |
10.1016/j.apsb.2020.12.020 |
2021 |
Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management. |
PTEN |
| 92 |
34624316 |
10.1016/j.jbc.2021.101172 |
2021 |
Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma. |
PTEN |
| 93 |
34729049 |
10.4103/jcar.jcar_14_21 |
2021 |
Molecular characterization of lung carcinomas: A study on diagnostic, predictive, and prognostic markers using immunohistochemical analysis at a Tertiary Care Center in Uttarakhand, India. |
PTEN |
| 94 |
34771656 |
10.3390/cancers13215493 |
2021 |
High Expression of <i>PPM1D</i> Induces Tumors Phenotypically Similar to <i>TP53</i> Loss-of-Function Mutations in Mice. |
PTEN |
| 95 |
27698880 |
10.3892/ol.2016.4943 |
2020 |
Anticancer effect of deoxypodophyllotoxin induces apoptosis of human prostate cancer cells. |
PTEN |
| 96 |
28280620 |
10.21037/jgo.2017.01.14 |
2020 |
Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis. |
PTEN |
| 97 |
28539722 |
10.4103/0973-1296.204618 |
2020 |
Effect of <i>Helix aspersa</i> extract on TNFα, NF-κB and some tumor suppressor genes in breast cancer cell line Hs578T. |
PTEN |
| 98 |
28943948 |
10.3892/ol.2017.6721 |
2020 |
Analysis of the expression level and methylation of tumor protein p53, phosphatase and tensin homolog and mutS homolog 2 in N-methyl-N-nitrosourea-induced thymic lymphoma in C57BL/6 mice. |
PTEN |
| 99 |
29312508 |
|
2020 |
Curcumin combined with glycyrrhetinic acid inhibits the development of hepatocellular carcinoma cells by down-regulating the PTEN/PI3K/AKT signalling pathway. |
PTEN |
| 100 |
29805582 |
10.3892/ol.2018.8377 |
2020 |
Effects of aspirin on proliferation, invasion and apoptosis of Hep-2 cells via the PTEN/AKT/NF-κB/survivin signaling pathway. |
PTEN |
Datasets
Models
