| 1 |
35296646 |
10.1038/s41419-022-04684-1 |
2022 |
Dual BTK/SYK inhibition with CG-806 (luxeptinib) disrupts B-cell receptor and Bcl-2 signaling networks in mantle cell lymphoma. |
NFKBIA |
| 2 |
35600392 |
10.3389/fonc.2022.881801 |
2022 |
SOCS3 Acts as an Onco-immunological Biomarker With Value in Assessing the Tumor Microenvironment, Pathological Staging, Histological Subtypes, Therapeutic Effect, and Prognoses of Several Types of Cancer. |
NFKBIA |
| 3 |
35885481 |
10.3390/diagnostics12071575 |
2022 |
Cell-Free DNA for Genomic Analysis in Primary Mediastinal Large B-Cell Lymphoma. |
NFKBIA |
| 4 |
32817282 |
10.3324/haematol.2019.236455 |
2021 |
A three-gene signature based on <i>MYC</i>, <i>BCL-2</i> and <i>NFKBIA</i> improves risk stratification in diffuse large B-cell lymphoma. |
NFKBIA |
| 5 |
32961552 |
10.1182/blood.2020007507 |
2021 |
Mutational landscape of gray zone lymphoma. |
NFKBIA |
| 6 |
33757561 |
10.1186/s13104-021-05521-y |
2021 |
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) versus adult T-cell leukemia/lymphoma (ATLL). |
NFKBIA |
| 7 |
33824284 |
10.1038/s41419-021-03638-3 |
2021 |
Single loss of a Trp53 allele triggers an increased oxidative, DNA damage and cytokine inflammatory responses through deregulation of IκBα expression. |
NFKBIA |
| 8 |
33847741 |
10.1182/bloodadvances.2020003431 |
2021 |
Deciphering the mechanisms of CC-122 resistance in DLBCL via a genome-wide CRISPR screen. |
NFKBIA |
| 9 |
34113355 |
10.3389/fimmu.2021.684424 |
2021 |
Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection. |
NFKBIA |
| 10 |
34405005 |
10.7150/jca.60390 |
2021 |
Serial surveillance by circulating tumor DNA profiling after chimeric antigen receptor T therapy for the guidance of r/r diffuse large B cell lymphoma precise treatment. |
NFKBIA |
| 11 |
32065117 |
10.12659/MSM.921649 |
2020 |
Huai Qi Huang Potentiates Dexamethasone-Mediated Lethality in Acute Lymphoblastic Leukemia Cells by Upregulating Glucocorticoid Receptor α. |
NFKBIA |
| 12 |
32246052 |
10.1038/s42003-020-0882-8 |
2020 |
Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses. |
NFKBIA |
| 13 |
30563911 |
10.1101/gr.241141.118 |
2019 |
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers. |
NFKBIA |
| 14 |
30887112 |
10.1007/s00109-019-01777-x |
2019 |
Activation of NF-κB in B cell receptor signaling through Bruton's tyrosine kinase-dependent phosphorylation of IκB-α. |
NFKBIA |
| 15 |
31344550 |
10.1016/j.virol.2019.07.011 |
2019 |
Association of polymorphisms in NFκB1 promoter and NFκBIA gene with the development of antibodies against HHV-8 in HIV-infected individuals. |
NFKBIA |
| 16 |
30116272 |
10.1186/s11658-018-0102-4 |
2018 |
The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells. |
NFKBIA |
| 17 |
26247921 |
10.1002/jcp.25122 |
2016 |
Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα. |
NFKBIA |
| 18 |
26526716 |
10.1053/j.gastro.2015.10.017 |
2016 |
BCL3 Reduces the Sterile Inflammatory Response in Pancreatic and Biliary Tissues. |
NFKBIA |
| 19 |
26647777 |
10.3892/ijo.2015.3247 |
2016 |
Diallyl trisulfide induces apoptosis by suppressing NF-κB signaling through destabilization of TRAF6 in primary effusion lymphoma. |
NFKBIA |
| 20 |
26727576 |
10.1038/oncsis.2015.44 |
2016 |
A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture. |
NFKBIA |
| 21 |
26740240 |
10.1038/srep18934 |
2016 |
Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction. |
NFKBIA |
| 22 |
27221964 |
10.1016/j.semcancer.2016.05.001 |
2016 |
NF-κB deregulation in Hodgkin lymphoma. |
NFKBIA |
| 23 |
27563822 |
10.18632/oncotarget.11507 |
2016 |
The BCR-ABL/NF-κB signal transduction network: a long lasting relationship in Philadelphia positive Leukemias. |
NFKBIA |
| 24 |
27566587 |
10.18632/oncotarget.11548 |
2016 |
Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas. |
NFKBIA |
| 25 |
25333578 |
10.3892/mmr.2014.2704 |
2015 |
An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IκBα. |
NFKBIA |
| 26 |
25394713 |
10.1038/leu.2014.324 |
2015 |
GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α. |
NFKBIA |
| 27 |
25916485 |
10.1007/s13346-015-0230-6 |
2015 |
TAT cell-penetrating peptide modulates inflammatory response and apoptosis in human lung epithelial cells. |
NFKBIA |
| 28 |
25985447 |
10.1055/s-0034-1398628 |
2015 |
Bortezomib Treatment can Overcome Glucocorticoid Resistance in Childhood B-cell Precursor Acute Lymphoblastic Leukemia Cell Lines. |
NFKBIA |
| 29 |
26237500 |
10.1097/CAD.0000000000000274 |
2015 |
Bortezomib and fenretinide induce synergistic cytotoxicity in mantle cell lymphoma through apoptosis, cell-cycle dysregulation, and IκBα kinase downregulation. |
NFKBIA |
| 30 |
26488500 |
10.12659/msm.895257 |
2015 |
Common Polymorphisms in the NFKBIA Gene and Cancer Susceptibility: A Meta-Analysis. |
NFKBIA |
| 31 |
26492364 |
10.1038/cddis.2015.260 |
2015 |
The RCAN1 inhibits NF-κB and suppresses lymphoma growth in mice. |
NFKBIA |
| 32 |
23697845 |
10.3109/10428194.2013.806799 |
2014 |
Bortezomib inhibits proteasomal degradation of IκBα and induces mitochondrial dependent apoptosis in activated B-cell diffuse large B-cell lymphoma. |
NFKBIA |
| 33 |
24992336 |
10.1371/journal.pone.0101314 |
2014 |
Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion. |
NFKBIA |
| 34 |
25280822 |
10.1016/j.jstrokecerebrovasdis.2014.05.032 |
2014 |
Anti-inflammatory and antiapoptotic effects of mesenchymal stem cells transplantation in rat brain with cerebral ischemia. |
NFKBIA |
| 35 |
22889356 |
10.3109/10428194.2012.720371 |
2013 |
Norcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells in vitro and in nude mouse xenografts. |
NFKBIA |
| 36 |
23441730 |
10.1042/BJ20121651 |
2013 |
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. |
NFKBIA |
| 37 |
23526666 |
10.1002/cbin.10101 |
2013 |
Genistein induces apoptotic cell death associated with inhibition of the NF-κB pathway in adult T-cell leukemia cells. |
NFKBIA |
| 38 |
23555990 |
10.1371/journal.pone.0060540 |
2013 |
Phosphorylated IκBα predicts poor prognosis in activated B-cell lymphoma and its inhibition with thymoquinone induces apoptosis via ROS release. |
NFKBIA |
| 39 |
23633516 |
10.1093/carcin/bgt144 |
2013 |
p53 dysfunction precedes the activation of nuclear factor-κB during disease progression in mice expressing Tax, a human T-cell leukemia virus type 1 oncoprotein. |
NFKBIA |
| 40 |
23665105 |
10.1016/j.ygcen.2013.04.033 |
2013 |
Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testis. |
NFKBIA |
| 41 |
23868181 |
10.1002/path.4239 |
2013 |
Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma. |
NFKBIA |
| 42 |
22065599 |
10.1182/blood-2011-08-374561 |
2012 |
Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies. |
NFKBIA |
| 43 |
22297640 |
10.1038/jid.2011.470 |
2012 |
Low herpesvirus entry mediator (HVEM) expression on dermal fibroblasts contributes to a Th2-dominant microenvironment in advanced cutaneous T-cell lymphoma. |
NFKBIA |
| 44 |
22393418 |
10.1371/journal.pone.0032584 |
2012 |
Blocking autophagy prevents bortezomib-induced NF-κB activation by reducing I-κBα degradation in lymphoma cells. |
NFKBIA |
| 45 |
22649101 |
10.1182/blood-2011-07-369397 |
2012 |
Essential role of TAK1 in regulating mantle cell lymphoma survival. |
NFKBIA |
| 46 |
22768179 |
10.1371/journal.pone.0039945 |
2012 |
Cross-talk between NFkB and the PI3-kinase/AKT pathway can be targeted in primary effusion lymphoma (PEL) cell lines for efficient apoptosis. |
NFKBIA |
| 47 |
20889926 |
10.1182/blood-2010-06-290437 |
2011 |
Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways. |
NFKBIA |
| 48 |
21224428 |
10.1158/1541-7786.MCR-10-0368 |
2011 |
Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL. |
NFKBIA |
| 49 |
21228035 |
10.3324/haematol.2010.030577 |
2011 |
Polymorphisms of nuclear factor-κB family genes are associated with development of multiple myeloma and treatment outcome in patients receiving bortezomib-based regimens. |
NFKBIA |
| 50 |
21406399 |
10.1158/0008-5472.CAN-10-3626 |
2011 |
CARMA3 is crucial for EGFR-Induced activation of NF-κB and tumor progression. |
NFKBIA |
| 51 |
21526201 |
10.1371/journal.pone.0018933 |
2011 |
Hepatitis C virus protects human B lymphocytes from Fas-mediated apoptosis via E2-CD81 engagement. |
NFKBIA |
| 52 |
21701779 |
10.3892/mmr.2011.515 |
2011 |
Analysis of CCL5 expression in classical Hodgkin's lymphoma L428 cell line. |
NFKBIA |
| 53 |
21896478 |
10.1074/jbc.M111.263384 |
2011 |
The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation. |
NFKBIA |
| 54 |
19648161 |
10.3324/haematol.2009.010157 |
2010 |
Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin's lymphoma. |
NFKBIA |
| 55 |
19857958 |
10.1016/j.ejca.2009.10.008 |
2010 |
Expression of NF-kappaB and IkappaB proteins in skeletal muscle of gastric cancer patients. |
NFKBIA |
| 56 |
19966855 |
10.1038/onc.2009.431 |
2010 |
TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway. |
NFKBIA |
| 57 |
20081837 |
10.1038/ncb2019 |
2010 |
Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA. |
NFKBIA |
| 58 |
20106524 |
10.1016/j.leukres.2009.12.014 |
2010 |
NFkappaB modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia. |
NFKBIA |
| 59 |
20193848 |
10.1016/j.cancergencyto.2009.11.005 |
2010 |
Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma. |
NFKBIA |
| 60 |
20359517 |
10.1016/j.tox.2010.03.014 |
2010 |
Gene expression profiles of human promyelocytic leukemia cell lines exposed to volatile organic compounds. |
NFKBIA |
| 61 |
20393484 |
10.1038/jid.2010.86 |
2010 |
Curcumin selectively induces apoptosis in cutaneous T-cell lymphoma cell lines and patients' PBMCs: potential role for STAT-3 and NF-kappaB signaling. |
NFKBIA |
| 62 |
20466000 |
10.1016/j.yexcr.2010.05.004 |
2010 |
Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations. |
NFKBIA |
| 63 |
20551178 |
10.1242/jcs.069476 |
2010 |
Interplay between BCL10, MALT1 and IkappaBalpha during T-cell-receptor-mediated NFkappaB activation. |
NFKBIA |
| 64 |
20558726 |
10.1074/jbc.M110.112128 |
2010 |
BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1. |
NFKBIA |
| 65 |
20607853 |
10.1002/gcc.20789 |
2010 |
Rare occurrence of biallelic CYLD gene mutations in classical Hodgkin lymphoma. |
NFKBIA |
| 66 |
20716621 |
10.1158/1055-9965.EPI-10-0389 |
2010 |
Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. |
NFKBIA |
| 67 |
20937806 |
10.1074/jbc.M110.159681 |
2010 |
Tumor necrosis factor alpha-induced inflammation is increased but apoptosis is inhibited by common food additive carrageenan. |
NFKBIA |
| 68 |
18992741 |
10.1016/j.yexcr.2008.10.010 |
2009 |
Role for protein geranylgeranylation in adult T-cell leukemia cell survival. |
NFKBIA |
| 69 |
19085995 |
10.1002/ibd.20821 |
2009 |
ROS, Hsp27, and IKKbeta mediate dextran sodium sulfate (DSS) activation of IkappaBa, NFkappaB, and IL-8. |
NFKBIA |
| 70 |
19219072 |
10.1038/onc.2009.6 |
2009 |
Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes. |
NFKBIA |
| 71 |
19223558 |
10.1158/1055-9965.EPI-08-1130 |
2009 |
Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma. |
NFKBIA |
| 72 |
19507254 |
10.1002/ijc.24502 |
2009 |
Mutations of NFKBIA, encoding IkappaB alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases. |
NFKBIA |
| 73 |
19573080 |
10.1111/j.1365-2141.2009.07790.x |
2009 |
Common genetic variants in candidate genes and risk of familial lymphoid malignancies. |
NFKBIA |
| 74 |
19773279 |
10.1136/oem.2008.044024 |
2009 |
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. |
NFKBIA |
| 75 |
20695076 |
10.4248/IJOS.09059 |
2009 |
CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex. |
NFKBIA |
| 76 |
18235046 |
10.1182/blood-2007-08-108654 |
2008 |
PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor. |
NFKBIA |
| 77 |
18574738 |
10.1080/08830180801939272 |
2008 |
Current topics in prevention of human T-cell leukemia virus type i infection: NF-kappa B inhibitors and APOBEC3. |
NFKBIA |
| 78 |
18636124 |
10.1371/journal.pone.0002816 |
2008 |
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. |
NFKBIA |
| 79 |
18728964 |
10.1080/10428190802304966 |
2008 |
Growth control of multiple myeloma cells through inhibition of glycogen synthase kinase-3. |
NFKBIA |
| 80 |
18852135 |
10.1158/1535-7163.MCT-08-0541 |
2008 |
Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines. |
NFKBIA |
| 81 |
16778832 |
10.1038/sj.cdd.4401996 |
2007 |
Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-kappaB and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner. |
NFKBIA |
| 82 |
17095757 |
10.1152/ajpgi.00380.2006 |
2007 |
Carrageenan induces interleukin-8 production through distinct Bcl10 pathway in normal human colonic epithelial cells. |
NFKBIA |
| 83 |
17310217 |
10.1038/labinvest.3700528 |
2007 |
IkappaBalpha independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells. |
NFKBIA |
| 84 |
17355202 |
10.1089/adt.2006.048 |
2007 |
A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor. |
NFKBIA |
| 85 |
17363905 |
10.1038/sj.emboj.7601622 |
2007 |
Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways. |
NFKBIA |
| 86 |
17367755 |
10.1016/j.bbrc.2007.03.002 |
2007 |
Induction of the nuclear IkappaB protein IkappaB-zeta upon stimulation of B cell antigen receptor. |
NFKBIA |
| 87 |
17540779 |
10.1152/ajpgi.00149.2007 |
2007 |
Bcl10 mediates LPS-induced activation of NF-kappaB and IL-8 in human intestinal epithelial cells. |
NFKBIA |
| 88 |
17550372 |
10.1111/j.1365-2249.2007.03427.x |
2007 |
Interleukin-13-induced type II polarization of inflammatory macrophages is mediated through suppression of nuclear factor-kappaB and preservation of IkappaBalpha in a T cell lymphoma. |
NFKBIA |
| 89 |
17555878 |
10.1016/j.bbagen.2007.04.011 |
2007 |
Nitric oxide induces apoptosis in cutaneous T cell lymphoma (HuT-78) by downregulating constitutive NF-kappaB. |
NFKBIA |
| 90 |
17681786 |
10.1016/j.phrs.2007.06.003 |
2007 |
Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells. |
NFKBIA |
| 91 |
17899540 |
10.1002/eji.200636759 |
2007 |
Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells. |
NFKBIA |
| 92 |
16289774 |
10.1016/j.canlet.2005.10.004 |
2006 |
The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkappaBalpha-deficient diffuse large B-cell lymphoma cell line. |
NFKBIA |
| 93 |
16388856 |
10.1016/j.imlet.2005.10.019 |
2006 |
In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline. Involvement of caspase cascades and IkappaBalpha phosphorylation. |
NFKBIA |
| 94 |
16401828 |
10.1182/blood-2005-07-2827 |
2006 |
Lack of IKBA coding region mutations in primary mediastinal large B-cell lymphoma and the host response subtype of diffuse large B-cell lymphoma. |
NFKBIA |
| 95 |
16498412 |
10.1038/sj.emboj.7600996 |
2006 |
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. |
NFKBIA |
| 96 |
16539850 |
10.1111/j.1745-7254.2006.00284.x |
2006 |
Deguelin inhibits expression of IkappaBalpha protein in Raji and U937 cells. |
NFKBIA |
| 97 |
16751281 |
10.1073/pnas.0507809103 |
2006 |
The role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas. |
NFKBIA |
| 98 |
15778364 |
10.4049/jimmunol.174.7.4060 |
2005 |
CD40 engagement prevents peroxisome proliferator-activated receptor gamma agonist-induced apoptosis of B lymphocytes and B lymphoma cells by an NF-kappaB-dependent mechanism. |
NFKBIA |
| 99 |
15782119 |
10.1038/sj.onc.1208564 |
2005 |
Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts. |
NFKBIA |
| 100 |
15858823 |
10.1002/ijc.21036 |
2005 |
Germline mutations and polymorphisms in the NFKBIA gene in Hodgkin lymphoma. |
NFKBIA |
Datasets
Models
