| 1 |
27999330 |
10.3390/genes7120130 |
2022 |
Dysregulated MicroRNA Expression Profiles and Potential Cellular, Circulating and Polymorphic Biomarkers in Non-Hodgkin Lymphoma. |
LYN |
| 2 |
34890905 |
10.1016/j.neo.2021.12.001 |
2022 |
DCZ0014, a novel compound in the therapy of diffuse large B-cell lymphoma via the B cell receptor signaling pathway. |
LYN |
| 3 |
35030632 |
10.1182/bloodadvances.2021006410 |
2022 |
Distinct clinical and genetic features of hepatitis B virus-associated follicular lymphoma in Chinese patients. |
LYN |
| 4 |
35217034 |
10.1016/j.metabol.2022.155164 |
2022 |
The interactions of CAP and LYN with the insulin signaling transducer CBL play an important role in polycystic ovary syndrome. |
LYN |
| 5 |
35255496 |
10.1182/bloodadvances.2021006147 |
2022 |
A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas. |
LYN |
| 6 |
35295854 |
10.3389/fcell.2022.838871 |
2022 |
Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells. |
LYN |
| 7 |
35323358 |
10.3390/curroncol29030158 |
2022 |
Novel, First-in-Human, Oral PCLX-001 Treatment in a Patient with Relapsed Diffuse Large B-Cell Lymphoma. |
LYN |
| 8 |
35411950 |
10.1002/cbf.3702 |
2022 |
USP7 sustains an active epigenetic program via stabilizing MLL2 and WDR5 in diffuse large B-cell lymphoma. |
LYN |
| 9 |
35592412 |
10.3389/fphar.2022.883835 |
2022 |
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis <i>Via</i> Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway. |
LYN |
| 10 |
35879731 |
10.1186/s40364-022-00401-4 |
2022 |
Dynamic change of soluble interleukin-2 receptor distinguished molecular heterogeneity and microenvironment alterations in diffuse large B-cell lymphoma. |
LYN |
| 11 |
35941532 |
10.1186/s10020-022-00518-0 |
2022 |
Interfering B cell receptor signaling via SHP-1/p-Lyn axis shows therapeutic potential in diffuse large B-cell lymphoma. |
LYN |
| 12 |
32219444 |
10.1182/blood.2019001417 |
2021 |
Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. |
LYN |
| 13 |
33004801 |
10.1038/s41419-020-03035-2 |
2021 |
BAFF-driven NLRP3 inflammasome activation in B cells. |
LYN |
| 14 |
33199837 |
10.1038/s41375-020-01091-3 |
2021 |
Leukemic cells expressing NCOR1-LYN are sensitive to dasatinib in vivo in a patient-derived xenograft mouse model. |
LYN |
| 15 |
33373915 |
10.1016/j.biopha.2020.111166 |
2021 |
Yishen-tongbi decoction inhibits excessive activation of B cells by activating the FcγRIIb/Lyn/SHP-1 pathway and attenuates the inflammatory response in CIA rats. |
LYN |
| 16 |
33512474 |
10.1182/blood.2020006528 |
2021 |
CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1. |
LYN |
| 17 |
34497200 |
10.11406/rinketsu.62.1131 |
2021 |
[Assessment of the leukemogenic mechanism of Ph-like acute lymphocytic leukemia for the identification of a novel therapeutic target]. |
LYN |
| 18 |
34651869 |
10.1002/hon.2933 |
2021 |
The resistance mechanisms and treatment strategies of BTK inhibitors in B-cell lymphoma. |
LYN |
| 19 |
31101761 |
10.1158/0008-5472.CAN-18-1503 |
2020 |
Phosphorylation of SOCS1 Inhibits the SOCS1-p53 Tumor Suppressor Axis. |
LYN |
| 20 |
31202171 |
10.1016/j.biopha.2019.109071 |
2020 |
Huaier extract enhances the treatment efficacy of imatinib in Ik6<sup>+</sup> Ph<sup>+</sup> acute lymphoblastic leukemia. |
LYN |
| 21 |
31362927 |
10.1182/bloodadvances.2018016162 |
2020 |
Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling. |
LYN |
| 22 |
31516031 |
10.4155/fmc-2018-0354 |
2020 |
'Piperazining' the catalytic gatekeepers: unraveling the pan-inhibition of SRC kinases; LYN, FYN and BLK by masitinib. |
LYN |
| 23 |
31804985 |
10.3855/jidc.10107 |
2020 |
Epidemiology of bacteremia after autologous hematopoietic stem cell transplantation in the absence of antibiotic prophylaxis. |
LYN |
| 24 |
31947626 |
10.3390/cancers12010204 |
2020 |
A Novel Cytological Model of B-Cell/Macrophage Biphenotypic Cell Hodgkin Lymphoma in <i>Ganp</i>-Transgenic Mice. |
LYN |
| 25 |
32565964 |
10.3892/ol.2020.11552 |
2020 |
Comprehensive characterization of driver genes in diffuse large B cell lymphoma. |
LYN |
| 26 |
29567799 |
10.1182/blood-2017-10-809210 |
2019 |
Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma. |
LYN |
| 27 |
29569971 |
10.1080/10428194.2018.1452213 |
2019 |
Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells. |
LYN |
| 28 |
29642007 |
10.1016/j.celrep.2018.03.069 |
2019 |
How Biophysical Forces Regulate Human B Cell Lymphomas. |
LYN |
| 29 |
30700840 |
10.1038/s41375-018-0366-8 |
2019 |
New roles for B cell receptor associated kinases: when the B cell is not the target. |
LYN |
| 30 |
30818878 |
10.3390/genes10030185 |
2019 |
Single Nucleotide Polymorphisms in <i>MIR143</i> Contribute to Protection Against Non-Hodgkin Lymphoma (NHL) in Caucasian Populations. |
LYN |
| 31 |
31046815 |
10.1186/s40359-019-0302-3 |
2019 |
Monitoring neurocognitive functioning in childhood cancer survivors: evaluation of CogState computerized assessment and the Behavior Rating Inventory of Executive Function (BRIEF). |
LYN |
| 32 |
31189540 |
10.1136/jclinpath-2019-205837 |
2019 |
Diffuse large B-cell lymphoma in Southeast Asian cohort: expression patterns of B-cell receptor (BCR) repertoire and its linkage with molecular subtypes and response to R-CHOP therapy. |
LYN |
| 33 |
31400706 |
10.1016/j.ejmech.2019.07.048 |
2019 |
Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines. |
LYN |
| 34 |
27297662 |
10.1038/ncomms11889 |
2018 |
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics. |
LYN |
| 35 |
28245378 |
10.7534/j.issn.1009-2137.2017.01.012 |
2018 |
[Effects of PCI-32765 and Dasatinib on the Acute Lymphoblastic Leukemic Cells and Their Mechanisms]. |
LYN |
| 36 |
29022919 |
10.1038/cddis.2017.472 |
2018 |
DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway. |
LYN |
| 37 |
29125235 |
10.1002/cam4.1257 |
2018 |
Comparison of the mRNA expression profile of B-cell receptor components in normal CD5-high B-lymphocytes and chronic lymphocytic leukemia: a key role of ZAP70. |
LYN |
| 38 |
26724941 |
10.1007/s12026-015-8777-3 |
2017 |
hIgD promotes human Burkitt lymphoma Daudi cell proliferation by accelerated G1/S transition via IgD receptor activity. |
LYN |
| 39 |
27176795 |
10.1038/bcj.2016.28 |
2017 |
Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan. |
LYN |
| 40 |
27582059 |
10.1126/scitranslmed.aaf5309 |
2017 |
Targeting BCL-2 and ABL/LYN in Philadelphia chromosome-positive acute lymphoblastic leukemia. |
LYN |
| 41 |
27641927 |
10.1016/j.phrs.2016.09.011 |
2017 |
Ibrutinib inhibition of Bruton protein-tyrosine kinase (BTK) in the treatment of B cell neoplasms. |
LYN |
| 42 |
27899526 |
10.1126/scisignal.aaf3949 |
2017 |
Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia. |
LYN |
| 43 |
28153771 |
10.1016/j.ebiom.2017.01.027 |
2017 |
B-cell Function Gene Mutations in Diffuse Large B-cell Lymphoma: A Retrospective Cohort Study. |
LYN |
| 44 |
28359287 |
10.1186/s13045-017-0447-6 |
2017 |
Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma. |
LYN |
| 45 |
28408464 |
10.1182/blood-2016-12-758979 |
2017 |
Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group. |
LYN |
| 46 |
28666825 |
10.1016/j.toxlet.2017.06.010 |
2017 |
Triptonide acts as a novel potent anti-lymphoma agent with low toxicity mainly through inhibition of proto-oncogene Lyn transcription and suppression of Lyn signal pathway. |
LYN |
| 47 |
28972016 |
10.1182/blood-2017-06-743252 |
2017 |
Philadelphia chromosome-like acute lymphoblastic leukemia. |
LYN |
| 48 |
25682964 |
10.3109/10428194.2015.1017820 |
2016 |
The function of a novel immunophenotype candidate molecule PD-1 in chronic lymphocytic leukemia. |
LYN |
| 49 |
26110819 |
10.1371/journal.pone.0130195 |
2016 |
Establishment and Characterization of PCL12, a Novel CD5+ Chronic Lymphocytic Leukaemia Cell Line. |
LYN |
| 50 |
26308964 |
10.1080/15592294.2015.1078050 |
2016 |
Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia. |
LYN |
| 51 |
26404892 |
10.1111/bjh.13757 |
2016 |
Identification of novel kinase fusion transcripts in paediatric B cell precursor acute lymphoblastic leukaemia with IKZF1 deletion. |
LYN |
| 52 |
26514641 |
10.1093/jpepsy/jsv103 |
2016 |
The Association Between Motor Skills and Academic Achievement Among Pediatric Survivors of Acute Lymphoblastic Leukemia. |
LYN |
| 53 |
26517678 |
10.18632/oncotarget.5425 |
2016 |
Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance. |
LYN |
| 54 |
26731115 |
10.1371/journal.pone.0145872 |
2016 |
Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase. |
LYN |
| 55 |
27058227 |
10.1038/bcj.2016.11 |
2016 |
Myeloproliferative neoplasm with eosinophilia and T-lymphoblastic lymphoma with ETV6-LYN gene fusion. |
LYN |
| 56 |
24885312 |
10.1186/1471-2164-15-390 |
2015 |
In silico analyses reveal common cellular pathways affected by loss of heterozygosity (LOH) events in the lymphomagenesis of Non-Hodgkin's lymphoma (NHL). |
LYN |
| 57 |
25030870 |
|
2015 |
[Gastric mucosa-associated lymphoid tissue lymphoma with Schistosoma japonica infection: report of a case]. |
LYN |
| 58 |
25080849 |
10.1111/ejh.12427 |
2015 |
B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cells. |
LYN |
| 59 |
25222877 |
10.1016/j.ejmech.2014.09.018 |
2015 |
4-Amino-2-arylamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidin-7-(8H)-ones as BCR kinase inhibitors for B lymphoid malignancies. |
LYN |
| 60 |
25391967 |
10.1007/s11060-014-1655-3 |
2015 |
Differential expression of Toll-like receptor (TLR) and B cell receptor (BCR) signaling molecules in primary diffuse large B-cell lymphoma of the central nervous system. |
LYN |
| 61 |
25484043 |
10.4161/19420862.2014.979081 |
2015 |
Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells. |
LYN |
| 62 |
23121564 |
10.3109/10428194.2012.745071 |
2014 |
SAR103168: a tyrosine kinase inhibitor with therapeutic potential in myeloid leukemias. |
LYN |
| 63 |
23597135 |
10.3109/10428194.2013.796055 |
2014 |
MicroRNAs and B cell receptor signaling in chronic lymphocytic leukemia. |
LYN |
| 64 |
24366360 |
10.1182/blood-2013-09-525808 |
2014 |
The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis. |
LYN |
| 65 |
24667141 |
10.1016/j.ajpath.2014.01.036 |
2014 |
Global phosphoproteomic profiling reveals distinct signatures in B-cell non-Hodgkin lymphomas. |
LYN |
| 66 |
25171927 |
10.1182/blood-2013-12-546309 |
2014 |
Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients. |
LYN |
| 67 |
22781597 |
|
2013 |
[Screen of phosphopeptide specific for acute leukemia]. |
LYN |
| 68 |
22895079 |
10.4161/cbt.21460 |
2013 |
Oridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway. |
LYN |
| 69 |
22966017 |
10.1158/1078-0432.CCR-12-0397 |
2013 |
Quantitative immunofluorescence reveals the signature of active B-cell receptor signaling in diffuse large B-cell lymphoma. |
LYN |
| 70 |
23039362 |
10.3109/10428194.2012.736983 |
2013 |
Expression levels of Lyn, Syk, PLCγ2 and ERK in patients with chronic lymphocytic leukemia, and higher levels of Lyn are associated with a shorter treatment-free survival. |
LYN |
| 71 |
23231952 |
10.1158/1078-0432.CCR-12-1935 |
2013 |
Sorafenib inhibits cell migration and stroma-mediated bortezomib resistance by interfering B-cell receptor signaling and protein translation in mantle cell lymphoma. |
LYN |
| 72 |
23270582 |
10.3109/10428194.2012.754097 |
2013 |
B-cell receptor signaling in chronic lymphocytic leukemia leans on Lyn. |
LYN |
| 73 |
23422267 |
10.1186/2162-3619-2-4 |
2013 |
Targeting early B-cell receptor signaling induces apoptosis in leukemic mantle cell lymphoma. |
LYN |
| 74 |
23704093 |
10.1182/blood-2013-01-480244 |
2013 |
Runx1 is essential at two stages of early murine B-cell development. |
LYN |
| 75 |
23962443 |
10.1016/j.bcp.2013.08.009 |
2013 |
Sophoraflavanone G induces apoptosis of human cancer cells by targeting upstream signals of STATs. |
LYN |
| 76 |
21749309 |
10.3109/10428194.2011.594926 |
2012 |
Heterogeneous expression of Src tyrosine kinases Lyn, Fyn and Syk in classical Hodgkin lymphoma: prognostic implications. |
LYN |
| 77 |
22609829 |
10.1016/j.antiviral.2012.05.003 |
2012 |
Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growth in a murine model of lymphoma expressing Myc and Epstein-Barr virus LMP2A. |
LYN |
| 78 |
22612424 |
10.1517/13543784.2012.685650 |
2012 |
Tyrosine kinase inhibitors as potential drugs for B-cell lymphoid malignancies and autoimmune disorders. |
LYN |
| 79 |
22805580 |
10.1186/1478-811X-10-21 |
2012 |
Functions of the Lyn tyrosine kinase in health and disease. |
LYN |
| 80 |
22915648 |
10.1182/blood-2012-02-413252 |
2012 |
Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2. |
LYN |
| 81 |
20875408 |
10.1016/j.yexcr.2010.09.011 |
2011 |
Membrane-associated signaling in human B-lymphoma lines. |
LYN |
| 82 |
21463117 |
10.3109/10428194.2011.555890 |
2011 |
The potential for dasatinib in treating chronic lymphocytic leukemia, acute myeloid leukemia, and myeloproliferative neoplasms. |
LYN |
| 83 |
19732844 |
10.1016/j.cellbi.2009.08.009 |
2010 |
Gene networks involved in apoptosis induced by hyperthermia in human lymphoma U937 cells. |
LYN |
| 84 |
19965664 |
10.1182/blood-2009-08-237537 |
2010 |
Rituximab inhibits B-cell receptor signaling. |
LYN |
| 85 |
20043832 |
10.1186/1476-4598-8-132 |
2010 |
Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth. |
LYN |
| 86 |
20054396 |
10.1038/nature08638 |
2010 |
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. |
LYN |
| 87 |
20065290 |
10.1182/blood-2009-09-241943 |
2010 |
High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia. |
LYN |
| 88 |
20101619 |
10.1002/eji.200939848 |
2010 |
Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation. |
LYN |
| 89 |
20143445 |
10.1002/cncr.24953 |
2010 |
Killing tumor cells through their surface beta(2)-microglobulin or major histocompatibility complex class I molecules. |
LYN |
| 90 |
20370541 |
10.3109/10428191003728628 |
2010 |
Expression profiles of adult T-cell leukemia-lymphoma and associations with clinical responses to zidovudine and interferon alpha. |
LYN |
| 91 |
20561033 |
10.1111/j.1600-0609.2010.01492.x |
2010 |
The sphingolipid-rich rafts of ALK+ lymphomas downregulate the Lyn-Cbp/PAG signalosome. |
LYN |
| 92 |
20563869 |
10.1007/s00277-010-0998-x |
2010 |
Efficacy of MK-0457 and in combination with vorinostat against Philadelphia chromosome positive acute lymphoblastic leukemia cells. |
LYN |
| 93 |
20687794 |
10.3109/10428194.2010.505061 |
2010 |
How the microenvironment shapes chronic lymphocytic leukemia: the cytoskeleton connection. |
LYN |
| 94 |
19131553 |
10.1182/blood-2008-08-175901 |
2009 |
Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability. |
LYN |
| 95 |
19346216 |
10.1074/mcp.M800515-MCP200 |
2009 |
Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma. |
LYN |
| 96 |
19347730 |
10.1080/10428190802709438 |
2009 |
Activity of FB2, a novel dual Abl/Src tyrosine kinase inhibitor, against imatinib-resistant chronic myeloid leukemia in vivo and in vitro. |
LYN |
| 97 |
17823310 |
10.1182/blood-2007-04-087775 |
2008 |
HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration. |
LYN |
| 98 |
17998938 |
10.1038/sj.onc.1210921 |
2008 |
Activation of Rac1 and the exchange factor Vav3 are involved in NPM-ALK signaling in anaplastic large cell lymphomas. |
LYN |
| 99 |
18070987 |
10.1182/blood-2007-05-090985 |
2008 |
Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts. |
LYN |
| 100 |
18579586 |
10.1128/JVI.00843-08 |
2008 |
Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn. |
LYN |
Datasets
Models
