1 |
34597466 |
10.1002/pbc.29361 |
2022 |
Clonal dynamics in pediatric B-cell precursor acute lymphoblastic leukemia with very early relapse. |
WHSC1 |
2 |
35124168 |
10.1016/j.jsbmb.2022.106068 |
2022 |
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia. |
WHSC1 |
3 |
33147938 |
10.3324/haematol.2020.259226 |
2021 |
Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations |
WHSC1 |
4 |
33469000 |
10.1038/s41420-021-00402-6 |
2021 |
Histone methyltransferase WHSC1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic BCL2. |
WHSC1 |
5 |
31697823 |
10.1182/blood.2019002220 |
2020 |
Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia. |
WHSC1 |
6 |
32332049 |
10.1158/1541-7786.MCR-20-0092 |
2020 |
The NSD2 p.E1099K Mutation Is Enriched at Relapse and Confers Drug Resistance in a Cell Context-Dependent Manner in Pediatric Acute Lymphoblastic Leukemia. |
WHSC1 |
7 |
32826945 |
10.1038/s42003-020-01186-8 |
2020 |
Proteosomal degradation of NSD2 by BRCA1 promotes leukemia cell differentiation. |
WHSC1 |
8 |
30171259 |
10.1038/s41388-018-0474-y |
2019 |
An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia. |
WHSC1 |
9 |
30471851 |
10.1016/j.bbrc.2018.11.037 |
2019 |
Identification of LEM-14 inhibitor of the oncoprotein NSD2. |
WHSC1 |
10 |
31221981 |
10.1038/s12276-019-0230-6 |
2019 |
The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism. |
WHSC1 |
11 |
29755111 |
10.1038/s41417-018-0022-5 |
2018 |
Genomic landscape and prognostic analysis of mantle cell lymphoma. |
WHSC1 |
12 |
27872090 |
10.1158/0008-5472.CAN-16-1303 |
2017 |
Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia. |
WHSC1 |
13 |
25790293 |
10.1038/ncomms7604 |
2015 |
Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia. |
WHSC1 |
14 |
26294725 |
10.3324/haematol.2015.129692 |
2015 |
Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation. |
WHSC1 |
15 |
23823660 |
10.1038/leu.2013.204 |
2014 |
Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies. |
WHSC1 |
16 |
24682267 |
10.1182/blood-2013-07-517177 |
2014 |
The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. |
WHSC1 |
17 |
24145436 |
10.1073/pnas.1314608110 |
2013 |
Landscape of somatic mutations and clonal evolution in mantle cell lymphoma. |
WHSC1 |