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# pmid doi year title Hugo_Symbol
1 35089437 10.1007/s00018-022-04139-y 2022 A20 undermines alternative NF-κB activity and expression of anti-apoptotic genes in Helicobacter pylori infection. TRAF3
2 35332215 10.1038/s41598-022-09112-0 2022 Evaluation of 41 single nucleotide polymorphisms in canine diffuse large B-cell lymphomas using MassARRAY. TRAF3
3 35726023 10.1038/s41684-022-00998-x 2022 The genomic landscape of canine diffuse large B-cell lymphoma identifies distinct subtypes with clinical and therapeutic implications. TRAF3
4 35789025 10.1002/hon.3045 2022 Mechanisms underlying synergism between circularized tumor necrosis factor-related apoptosis inducing ligand and bortezomib in bortezomib-sensitive or -resistant myeloma cells. TRAF3
5 33184494 10.1038/s41375-020-01088-y 2021 A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma. TRAF3
6 33206936 10.1182/blood.2020005650 2021 Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia. TRAF3
7 33503336 10.1002/cnr2.1335 2021 Novel germline TRAF3IP3 mutation in a dyad with familial acute B lymphoblastic leukemia. TRAF3
8 33639170 10.1016/j.jbc.2021.100465 2021 TNF receptor-associated factor 3 restrains B-cell receptor signaling in normal and malignant B cells. TRAF3
9 33847741 10.1182/bloodadvances.2020003431 2021 Deciphering the mechanisms of CC-122 resistance in DLBCL via a genome-wide CRISPR screen. TRAF3
10 34202989 10.3390/pharmaceutics13060911 2021 ChoK-Full of Potential: Choline Kinase in B Cell and T Cell Malignancies. TRAF3
11 34255829 10.1182/blood.2021011247 2021 DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis. TRAF3
12 34651869 10.1002/hon.2933 2021 The resistance mechanisms and treatment strategies of BTK inhibitors in B-cell lymphoma. TRAF3
13 31666375 10.1128/JVI.01553-19 2020 USP7-Dependent Regulation of TRAF Activation and Signaling by a Viral Interferon Regulatory Factor Homologue. TRAF3
14 32038991 10.3389/fonc.2020.00023 2020 The Genetic and Molecular Basis for Canine Models of Human Leukemia and Lymphoma. TRAF3
15 32773475 10.1097/QAD.0000000000002653 2020 Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV. TRAF3
16 33154951 10.3389/fonc.2020.591577 2020 Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies. TRAF3
17 33323169 10.1016/j.tvjl.2020.105575 2020 The prevalence and characterisation of TRAF3 and POT1 mutations in canine B-cell lymphoma. TRAF3
18 30563911 10.1101/gr.241141.118 2019 Human papillomavirus and the landscape of secondary genetic alterations in oral cancers. TRAF3
19 31320741 10.1038/s41598-019-46906-1 2019 Systematic Review of Somatic Mutations in Splenic Marginal Zone Lymphoma. TRAF3
20 31378966 10.1002/ajh.25600 2019 Clinical and molecular characteristics of lymphoplasmacytic lymphoma not associated with an IgM monoclonal protein: A multicentric study of the Rete Ematologica Lombarda (REL) network. TRAF3
21 29765142 10.1038/s41379-018-0064-0 2018 Targeted deep sequencing of gastric marginal zone lymphoma identified alterations of TRAF3 and TNFAIP3 that were mutually exclusive for MALT1 rearrangement. TRAF3
22 30018073 10.1084/jem.20180210 2018 CRL4<sup>DCAF2</sup> negatively regulates IL-23 production in dendritic cells and limits the development of psoriasis. TRAF3
23 30687320 10.3389/fimmu.2018.03114 2018 Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice. TRAF3
24 28682481 10.1002/path.4933 2017 Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma. TRAF3
25 29296923 10.1182/bloodadvances.2017009670 2017 The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency. TRAF3
26 26740054 10.1016/j.leukres.2015.12.005 2016 Signaling mechanisms of bortezomib in TRAF3-deficient mouse B lymphoma and human multiple myeloma cells. TRAF3
27 26755589 10.1073/pnas.1514586113 2016 Nuclear TRAF3 is a negative regulator of CREB in B cells. TRAF3
28 27752131 10.1038/srep35349 2016 TRAF3 deficiency promotes metabolic reprogramming in B cells. TRAF3
29 25428260 10.1038/leu.2014.330 2015 KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype. TRAF3
30 25468570 10.1182/blood-2014-10-602714 2015 Genetic inactivation of TRAF3 in canine and human B-cell lymphoma. TRAF3
31 25921526 10.1016/j.celrep.2015.03.059 2015 An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression. TRAF3
32 25960828 10.4172/1948-5956.1000327 2015 Targeting TRAF3 Downstream Signaling Pathways in B cell Neoplasms. TRAF3
33 26308964 10.1080/15592294.2015.1078050 2015 Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia. TRAF3
34 26377837 10.1101/gr.194449.115 2015 Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background. TRAF3
35 24362935 10.1038/nm.3435 2014 Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma. TRAF3
36 24418753 10.1016/j.leukres.2013.12.016 2014 Expression and function of a novel isoform of Sox5 in malignant B cells. TRAF3
37 24739416 10.4161/cc.28895 2014 The TRAF3 adaptor protein drives proliferation of anaplastic large cell lymphoma cells by regulating multiple signaling pathways. TRAF3
38 25200342 10.1186/s13045-014-0056-6 2014 Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. TRAF3
39 23333941 10.1016/j.gene.2012.12.026 2013 Identification and characterization of receptor-interacting protein 2 as a TNFR-associated factor 3 binding partner. TRAF3
40 23868181 10.1002/path.4239 2013 Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma. TRAF3
41 24131623 10.1186/1471-2407-13-481 2013 N-benzyladriamycin-14-valerate (AD 198) exhibits potent anti-tumor activity on TRAF3-deficient mouse B lymphoma and human multiple myeloma. TRAF3
42 24239354 10.1016/j.celrep.2013.10.022 2013 Context-specific BAFF-R signaling by the NF-κB and PI3K pathways. TRAF3
43 24260396 10.1371/journal.pone.0080470 2013 SUMOylation is required for optimal TRAF3 signaling capacity. TRAF3
44 22033491 10.1038/leu.2011.309 2012 Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice. TRAF3
45 22469134 10.1111/j.1365-2141.2012.09113.x 2012 Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma. TRAF3
46 22711886 10.4049/jimmunol.1200814 2012 TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice. TRAF3
47 20889926 10.1182/blood-2010-06-290437 2011 Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways. TRAF3
48 21228035 10.3324/haematol.2010.030577 2011 Polymorphisms of nuclear factor-κB family genes are associated with development of multiple myeloma and treatment outcome in patients receiving bortezomib-based regimens. TRAF3
49 21454205 10.3816/CLML.2011.n.021 2011 High-throughput genomic analysis in Waldenström's macroglobulinemia. TRAF3
50 21881048 10.1182/blood-2011-06-359166 2011 Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma. TRAF3
51 20410275 10.1128/JVI.00344-10 2010 Epstein-Barr virus latent membrane protein 1 modulates distinctive NF- kappaB pathways through C-terminus-activating region 1 to regulate epidermal growth factor receptor expression. TRAF3
52 21041452 10.1084/jem.20100857 2010 A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. TRAF3
53 19540595 10.1016/j.molimm.2009.05.178 2009 TRAF1 is involved in the classical NF-kappaB activation and CD30-induced alternative activity in Hodgkin's lymphoma cells. TRAF3
54 19667091 10.4049/jimmunol.0900442 2009 Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1. TRAF3
55 19693093 10.1038/leu.2009.149 2009 Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33). TRAF3
56 19698991 10.1016/j.molimm.2009.07.029 2009 TNF receptor-associated factor 1 is a positive regulator of the NF-kappaB alternative pathway. TRAF3
57 19917778 10.1084/jem.20091802 2009 Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets. TRAF3
58 19954665 2009 [The action mechanisms of unclassical NF-kappaB activity and TRAF3 expression in Hodgkin's lymphoma cells]. TRAF3
59 18042799 10.1182/blood-2007-07-100032 2008 The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis. TRAF3
60 17878343 10.4049/jimmunol.179.7.4473 2007 Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B. TRAF3
61 16247482 10.1038/sj.onc.1209023 2006 LMP1 signaling and activation of NF-kappaB in LMP1 transgenic mice. TRAF3
62 15386359 10.1002/ijc.20503 2005 TRAF interactions with raft-like buoyant complexes, better than TRAF rates of degradation, differentiate signaling by CD40 and EBV latent membrane protein 1. TRAF3
63 15514968 10.1002/ijc.20654 2005 In vitro EBV-infected subline of KMH2, derived from Hodgkin lymphoma, expresses only EBNA-1, while CD40 ligand and IL-4 induce LMP-1 but not EBNA-2. TRAF3
64 15914563 10.1182/blood-2004-10-3898 2005 Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis. TRAF3
65 16227255 10.1128/JVI.79.21.13326-13337.2005 2005 In nasopharyngeal carcinoma cells, Epstein-Barr virus LMP1 interacts with galectin 9 in membrane raft elements resistant to simvastatin. TRAF3
66 15663562 10.1111/j.1365-2222.2004.02119.x 2004 Biological effects of montelukast, a cysteinyl-leukotriene receptor-antagonist, on T lymphocytes. TRAF3
67 12972530 10.1200/JCO.2003.09.037 2003 Emerging applications of the tumor necrosis factor family of ligands and receptors in cancer therapy. TRAF3
68 12220533 10.1016/s0003-9861(02)00369-7 2002 CD40-mediated tumor necrosis factor receptor-associated factor 3 signaling upregulates IL-4-induced germline Cepsilon transcription in a human B cell line. TRAF3
69 12471121 10.4049/jimmunol.169.12.6883 2002 TNFR-associated factor-3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kappa B activation and IL-10 production. TRAF3
70 11600226 10.1016/s0198-8859(01)00284-1 2001 Expression and function of TRAF-3 splice-variant isoforms in human lymphoma cell lines. TRAF3
71 11023520 2000 Hodgkin disease: pharmacologic intervention of the CD40-NF kappa B pathway by a protease inhibitor. TRAF3
72 11046039 10.4049/jimmunol.165.9.5084 2000 TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. TRAF3
73 11144929 10.1038/modpathol.3880243 2000 Expression of the tumor necrosis factor receptor-associated factors (TRAFs) 1 and 2 is a characteristic feature of Hodgkin and Reed-Sternberg cells. TRAF3
74 10187771 10.1074/jbc.274.15.9962 1999 Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase. TRAF3
75 10202013 1999 An 11-amino acid sequence in the cytoplasmic domain of CD40 is sufficient for activation of c-Jun N-terminal kinase, activation of MAPKAP kinase-2, phosphorylation of I kappa B alpha, and protection of WEHI-231 cells from anti-IgM-induced growth arrest. TRAF3
76 10225457 10.1002/(sici)1097-0215(19990517)81:4&lt;645::aid-ijc22&gt;3.0.co;2-0 1999 Evidence of LMP1-TRAF3 interactions in glycosphingolipid-rich complexes of lymphoblastoid and nasopharyngeal carcinoma cells. TRAF3
77 10400794 10.1128/JVI.73.8.6953-6963.1999 1999 Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus. TRAF3
78 10509816 10.1016/s0161-5890(99)00079-6 1999 TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF-kappaB activation. TRAF3
79 9990039 10.1073/pnas.96.4.1421 1999 Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation. TRAF3
80 9516144 1998 Gene expression by single Reed-Sternberg cells: pathways of apoptosis and activation. TRAF3
81 9580648 10.1056/NEJM199805143382003 1998 Epstein-Barr virus and a cellular signaling pathway in lymphomas from immunosuppressed patients. TRAF3
82 9686578 1998 TNF receptor-associated factor-3 signaling mediates activation of p38 and Jun N-terminal kinase, cytokine secretion, and Ig production following ligation of CD40 on human B cells. TRAF3
83 9032281 10.1128/MCB.17.3.1535 1997 Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2. TRAF3
84 9037073 10.1073/pnas.94.4.1447 1997 The Epstein-Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation. TRAF3
85 9168896 10.1006/bbrc.1997.6509 1997 Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily. TRAF3
86 9366415 1997 Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes. TRAF3
87 8663299 10.1074/jbc.271.25.14661 1996 TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor. TRAF3