| 1 |
34210682 |
10.1158/1078-0432.CCR-21-0553 |
2022 |
Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia. |
STAT5B |
| 2 |
34587248 |
10.1182/blood.2021012976 |
2022 |
Genome-wide CRISPR-Cas9 screen identifies rationally designed combination therapies for CRLF2-rearranged Ph-like ALL. |
STAT5B |
| 3 |
34895266 |
10.1186/s13000-021-01173-5 |
2022 |
Clinicopathological and molecular genomic features of monomorphic epitheliotropic intestinal T-cell lymphoma in the Chinese population: a study of 20 cases. |
STAT5B |
| 4 |
35354799 |
10.1038/s41420-022-00953-2 |
2022 |
Ablation of Cbl-b and c-Cbl in dendritic cells causes spontaneous liver cirrhosis via altering multiple properties of CD103<sup>+</sup> cDC1s. |
STAT5B |
| 5 |
35452696 |
10.1016/j.humpath.2022.04.002 |
2022 |
B-cell lymphoma-2 downregulation is a useful feature supporting a neoplastic phenotype in mature T-cell lymphomas. |
STAT5B |
| 6 |
35551151 |
10.1097/PAS.0000000000001914 |
2022 |
Targeted Next-generation Sequencing Reveals a Wide Morphologic and Immunophenotypic Spectrum of Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma. |
STAT5B |
| 7 |
35708139 |
10.3324/haematol.2022.281226 |
2022 |
Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome. |
STAT5B |
| 8 |
35895386 |
10.1111/bjd.21791 |
2022 |
Primary cutaneous peripheral T-cell lymphomas with a T-follicular helper phenotype: an integrative clinical, pathological and molecular case series study. |
STAT5B |
| 9 |
36045346 |
10.1186/s12943-022-01640-7 |
2022 |
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma. |
STAT5B |
| 10 |
31123029 |
10.3324/haematol.2019.216986 |
2021 |
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia. |
STAT5B |
| 11 |
31822801 |
10.1038/s41379-019-0415-5 |
2021 |
Mutational profile and EBV strains of extranodal NK/T-cell lymphoma, nasal type in Latin America. |
STAT5B |
| 12 |
32479694 |
10.1002/cyto.b.21882 |
2021 |
Single-cell profiling of pediatric T-cell acute lymphoblastic leukemia: Impact of PTEN exon 7 mutation on PI3K/Akt and JAK-STAT signaling pathways. |
STAT5B |
| 13 |
32619110 |
10.1080/10520295.2020.1770332 |
2021 |
Silencing Stat3 inhibits viability and induces apoptosis in BGC-823 human gastric cancer cell line. |
STAT5B |
| 14 |
32643174 |
10.1111/ijd.15036 |
2021 |
Mapping signal transducer and activator of transcription (STAT) activity in different stages of mycosis fungoides and Sezary syndrome. |
STAT5B |
| 15 |
33410350 |
10.1080/10428194.2020.1869964 |
2021 |
<i>STAT3</i> and <i>STAT5B</i> mutations have unique distribution in T-cell large granular lymphocyte proliferations and advanced myeloid neoplasms. |
STAT5B |
| 16 |
34299796 |
10.3390/ijerph18147345 |
2021 |
The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border. |
STAT5B |
| 17 |
34535769 |
10.1038/s41388-021-02012-z |
2021 |
Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia. |
STAT5B |
| 18 |
34680385 |
10.3390/cancers13205238 |
2021 |
A Recurrent <i>STAT5B<sup>N642H</sup></i> Driver Mutation in Feline Alimentary T Cell Lymphoma. |
STAT5B |
| 19 |
30516071 |
10.1080/10428194.2018.1543875 |
2020 |
MicroRNA-221 sensitizes chronic myeloid leukemia cells to imatinib by targeting STAT5. |
STAT5B |
| 20 |
31394087 |
10.1016/j.yexmp.2019.104294 |
2020 |
RHOA G17V mutation in angioimmunoblastic T-cell lymphoma: A potential biomarker for cytological assessment. |
STAT5B |
| 21 |
31774495 |
10.1182/blood.2019001904 |
2020 |
Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant-associated ALCL. |
STAT5B |
| 22 |
31914529 |
10.3760/cma.j.issn.0529-5807.2020.01.004 |
2020 |
[Monomorphic epitheliotropic intestinal T-cell lymphoma: a clinicopathological analysis of twelve cases]. |
STAT5B |
| 23 |
31992840 |
10.1038/s41375-019-0685-4 |
2020 |
Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation. |
STAT5B |
| 24 |
32188095 |
10.3390/cancers12030702 |
2020 |
<i>STAT3</i> Mutation Is Associated with STAT3 Activation in CD30<sup>+</sup> ALK<sup>-</sup> ALCL. |
STAT5B |
| 25 |
32271188 |
10.1097/PAS.0000000000001470 |
2020 |
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group. |
STAT5B |
| 26 |
26385310 |
10.1016/j.leukres.2015.09.004 |
2019 |
STAT transcript levels in childhood acute lymphoblastic leukemia: STAT1 and STAT3 transcript correlations. |
STAT5B |
| 27 |
28356009 |
10.2174/1871520617666170327115657 |
2019 |
ECPIRM, a Potential Therapeutic Agent for Cutaneous T-Cell Lymphoma, Inhibits Cell Proliferation and Promotes Apoptosis via a JAK/STAT Pathway. |
STAT5B |
| 28 |
28760054 |
10.1080/10428194.2017.1357176 |
2019 |
Successful treatment of a patient with acute promyelocytic leukemia with a STAT5B/RARA fusion gene using decitabine. |
STAT5B |
| 29 |
29200404 |
10.1172/JCI94509 |
2019 |
STAT5BN642H is a driver mutation for T cell neoplasia. |
STAT5B |
| 30 |
29262599 |
10.18632/oncotarget.21790 |
2019 |
Fusion of the genes ataxin 2 like, <i>ATXN2L</i>, and Janus kinase 2, <i>JAK2</i>, in cutaneous CD4 positive T-cell lymphoma. |
STAT5B |
| 31 |
29337025 |
10.1016/j.humpath.2018.01.005 |
2019 |
Hepatosplenic T-cell Lymphoma: a review of clinicopathologic features, pathogenesis, and prognostic factors. |
STAT5B |
| 32 |
29650799 |
10.1182/blood-2017-11-814913 |
2019 |
Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma. |
STAT5B |
| 33 |
29682185 |
10.18632/oncotarget.24698 |
2019 |
STAT5 inhibition induces TRAIL/DR4 dependent apoptosis in peripheral T-cell lymphoma. |
STAT5B |
| 34 |
29740158 |
10.1038/s41375-018-0127-8 |
2019 |
Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia. |
STAT5B |
| 35 |
30450688 |
10.1111/1346-8138.14702 |
2019 |
Papuloerythroderma-like cutaneous involvement of a CD62L<sup>-</sup> subclone of T-cell prolymphocytic leukemia. |
STAT5B |
| 36 |
30964854 |
10.12659/MSM.914934 |
2019 |
The Signal Transducer and Activator of Transcription 5B (STAT5B) Gene Promotes Proliferation and Drug Resistance of Human Mantle Cell Lymphoma Cells by Activating the Akt Signaling Pathway. |
STAT5B |
| 37 |
31175292 |
10.1038/s41467-019-10422-7 |
2019 |
Structural and functional consequences of the STAT5B<sup>N642H</sup> driver mutation. |
STAT5B |
| 38 |
27600764 |
10.1038/ncomms12602 |
2018 |
Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations. |
STAT5B |
| 39 |
27911132 |
10.1080/10428194.2016.1262952 |
2018 |
A new acute myeloid leukemia case with STAT5B-RARA gene fusion due to 17q21.2 interstitial deletion. |
STAT5B |
| 40 |
28214593 |
10.1016/j.mce.2017.02.019 |
2018 |
JAK/STAT pathway directed therapy of T-cell leukemia/lymphoma: Inspired by functional and structural genomics. |
STAT5B |
| 41 |
29115375 |
10.3892/ijmm.2017.3205 |
2018 |
Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib. |
STAT5B |
| 42 |
29615001 |
10.1186/s12885-018-4311-z |
2018 |
Epstein-Barr virus positive peripheral T cell lymphoma with novel variants in STAT5B of a pediatric patient: a case report. |
STAT5B |
| 43 |
26500062 |
10.1038/onc.2015.405 |
2017 |
Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia. |
STAT5B |
| 44 |
26854024 |
10.1038/leu.2016.13 |
2017 |
JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma. |
STAT5B |
| 45 |
27174491 |
10.1038/leu.2016.83 |
2017 |
MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. |
STAT5B |
| 46 |
27342034 |
10.1016/j.jid.2016.04.027 |
2017 |
Sézary Syndrome: Translating Genetic Diversity into Personalized Medicine. |
STAT5B |
| 47 |
28122867 |
10.1158/2159-8290.CD-16-0330 |
2017 |
The Genetic Basis of Hepatosplenic T-cell Lymphoma. |
STAT5B |
| 48 |
28373165 |
10.1158/2159-8290.CD-17-0160 |
2017 |
It Takes a Village to Unmask HSTL. |
STAT5B |
| 49 |
28424246 |
10.1084/jem.20160894 |
2017 |
Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2. |
STAT5B |
| 50 |
28671688 |
10.1038/ng.3909 |
2017 |
The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia. |
STAT5B |
| 51 |
25586472 |
10.1038/ncomms7025 |
2016 |
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells. |
STAT5B |
| 52 |
25629986 |
10.3109/10428194.2015.1007454 |
2016 |
Novel STAT5B-RARA fusion transcript in acute promyelocytic leukemia: identification and treatment response. |
STAT5B |
| 53 |
25915535 |
10.18632/oncotarget.3837 |
2016 |
Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma. |
STAT5B |
| 54 |
26192917 |
10.1038/ng.3358 |
2016 |
Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma. |
STAT5B |
| 55 |
26297271 |
10.1016/j.clml.2015.02.012 |
2016 |
Investigating the Role of JAK/STAT Pathway on Dasatinib-Induced Apoptosis for CML Cell Model K562. |
STAT5B |
| 56 |
26338970 |
10.18632/oncotarget.5009 |
2016 |
Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis. |
STAT5B |
| 57 |
26379152 |
10.1097/PAS.0000000000000503 |
2016 |
Primary CNS T-cell Lymphomas: A Clinical, Morphologic, Immunophenotypic, and Molecular Analysis. |
STAT5B |
| 58 |
26415585 |
10.1038/ncomms9470 |
2016 |
Genomic analyses reveal recurrent mutations in epigenetic modifiers and the JAK-STAT pathway in Sézary syndrome. |
STAT5B |
| 59 |
26431836 |
10.1007/s11899-015-0289-7 |
2016 |
Molecular Pathogenesis of Peripheral T Cell Lymphoma. |
STAT5B |
| 60 |
26536348 |
10.1371/journal.pone.0141906 |
2016 |
Concurrent Mutations in ATM and Genes Associated with Common γ Chain Signaling in Peripheral T Cell Lymphoma. |
STAT5B |
| 61 |
26917488 |
10.1111/bjh.13952 |
2016 |
Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia. |
STAT5B |
| 62 |
24947020 |
10.1038/leu.2014.200 |
2015 |
Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas. |
STAT5B |
| 63 |
24972766 |
10.3324/haematol.2014.104992 |
2015 |
The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse. |
STAT5B |
| 64 |
25013898 |
10.1371/journal.pone.0100822 |
2015 |
Reliable quantification of protein expression and cellular localization in histological sections. |
STAT5B |
| 65 |
25355872 |
10.1128/JVI.02570-14 |
2015 |
High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. |
STAT5B |
| 66 |
25749351 |
10.1016/j.cancergen.2014.12.001 |
2015 |
Rare occurrence of a STAT5B N642H mutation in adult T-cell acute lymphoblastic leukemia. |
STAT5B |
| 67 |
25907517 |
10.1111/apm.12381 |
2015 |
Nucleophosmin overexpression is associated with poor survival in astrocytoma. |
STAT5B |
| 68 |
24367274 |
10.1371/journal.pgen.1003997 |
2014 |
Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia. |
STAT5B |
| 69 |
24523507 |
10.4049/jimmunol.1302951 |
2014 |
Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner. |
STAT5B |
| 70 |
24573384 |
10.1038/leu.2014.89 |
2014 |
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia. |
STAT5B |
| 71 |
23362870 |
10.1111/exd.12086 |
2013 |
The antihistamines clemastine and desloratadine inhibit STAT3 and c-Myc activities and induce apoptosis in cutaneous T-cell lymphoma cell lines. |
STAT5B |
| 72 |
23406773 |
10.1158/1078-0432.CCR-12-0284 |
2013 |
Molecular pathways: Jak/STAT pathway: mutations, inhibitors, and resistance. |
STAT5B |
| 73 |
23451206 |
10.1371/journal.pone.0057326 |
2013 |
Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells. |
STAT5B |
| 74 |
23457589 |
10.1371/journal.pone.0056600 |
2013 |
Enhanced T cell lymphoma in NOD.Stat5b transgenic mice is caused by hyperactivation of Stat5b in CD8+ thymocytes. |
STAT5B |
| 75 |
23716595 |
10.1128/MCB.01620-12 |
2013 |
STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6. |
STAT5B |
| 76 |
23768868 |
10.1016/j.leukres.2013.05.003 |
2013 |
Polymorphisms in JAK/STAT signaling pathway genes and risk of non-Hodgkin lymphoma. |
STAT5B |
| 77 |
23962443 |
10.1016/j.bcp.2013.08.009 |
2013 |
Sophoraflavanone G induces apoptosis of human cancer cells by targeting upstream signals of STATs. |
STAT5B |
| 78 |
22126101 |
10.3109/10428194.2011.645212 |
2012 |
Investigation and analysis of single nucleotide polymorphisms in Janus kinase/signal transducer and activator of transcription genes with leukemia. |
STAT5B |
| 79 |
22442148 |
10.1074/jbc.M111.319756 |
2012 |
Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies. |
STAT5B |
| 80 |
17225522 |
|
2011 |
[Expression and its significance of STAT3, STAT5, Survivin and Ki67 in nasal NK/T cell lymphoma]. |
STAT5B |
| 81 |
20438785 |
10.1016/j.humimm.2010.04.004 |
2011 |
Polymorphisms in innate immunity genes and risk of childhood leukemia. |
STAT5B |
| 82 |
20716621 |
10.1158/1055-9965.EPI-10-0389 |
2011 |
Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. |
STAT5B |
| 83 |
21268278 |
10.1002/pmic.201000569 |
2011 |
One-source peptide/phosphopeptide standards for accurate phosphorylation degree determination. |
STAT5B |
| 84 |
21606506 |
10.1084/jem.20101947 |
2011 |
Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia. |
STAT5B |
| 85 |
19709433 |
10.1186/1476-4598-8-67 |
2010 |
STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells. |
STAT5B |
| 86 |
20227268 |
10.1016/j.coi.2010.02.004 |
2010 |
STAT5 in B cell development and leukemia. |
STAT5B |
| 87 |
19047679 |
10.1182/blood-2008-07-166355 |
2009 |
BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3. |
STAT5B |
| 88 |
19393833 |
10.1053/j.seminoncol.2009.02.007 |
2009 |
Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches. |
STAT5B |
| 89 |
17890450 |
10.1182/blood-2007-04-084707 |
2008 |
A Stat5b transgene is capable of inducing CD8+ lymphoblastic lymphoma in the absence of normal TCR/MHC signaling. |
STAT5B |
| 90 |
17922009 |
10.1038/nm1659 |
2008 |
STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression. |
STAT5B |
| 91 |
18285272 |
10.1309/63H1A83HRTBQ07DB |
2008 |
Phosphorylated STAT5 represents a new possible prognostic marker in Hodgkin lymphoma. |
STAT5B |
| 92 |
18716132 |
10.1182/blood-2008-03-148726 |
2008 |
PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. |
STAT5B |
| 93 |
16125365 |
10.1016/j.cellsig.2005.07.013 |
2006 |
Characterization of STAT5B phosphorylation correlating with expression of cytokine-inducible SH2-containing protein (CIS). |
STAT5B |
| 94 |
16502315 |
10.1007/s00403-006-0647-3 |
2006 |
The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines. |
STAT5B |
| 95 |
15363129 |
|
2005 |
[Identification of acute leukemia-specific genes from leukemia recipient/sibling donor pairs by distinguishing study with oligonucleotide microarrays]. |
STAT5B |
| 96 |
15606748 |
10.1111/j.1432-1033.2004.04424.x |
2005 |
Regulation of STAT signalling by proteolytic processing. |
STAT5B |
| 97 |
15870688 |
10.1038/sj.onc.1208726 |
2005 |
Haploinsufficiency identifies STAT5 as a modifier of IL-7-induced lymphomas. |
STAT5B |
| 98 |
14556656 |
10.1111/j.1349-7006.2003.tb01365.x |
2004 |
Pre-B lymphomas in SL/Kh mice: a multifactorial disease model. |
STAT5B |
| 99 |
14695224 |
|
2004 |
Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome. |
STAT5B |
| 100 |
12835478 |
10.1084/jem.20021548 |
2003 |
Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma. |
STAT5B |
Datasets
Models
