| 1 |
35053500 |
10.3390/cancers14020338 |
2022 |
High ETV6 Levels Support Aggressive B Lymphoma Cell Survival and Predict Poor Outcome in Diffuse Large B-Cell Lymphoma Patients. |
PIM2 |
| 2 |
34625423 |
10.1158/0008-5472.CAN-21-1023 |
2021 |
Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies. |
PIM2 |
| 3 |
30658101 |
10.1016/j.lfs.2019.01.022 |
2019 |
PIM inhibitor SMI-4a induces cell apoptosis in B-cell acute lymphocytic leukemia cells via the HO-1-mediated JAK2/STAT3 pathway. |
PIM2 |
| 4 |
30340823 |
10.1016/j.bbrc.2018.09.062 |
2018 |
Proviral insertion in murine lymphomas 2 promotes stomach cancer progression by regulating apoptosis via reactive oxygen species-triggered endoplasmic reticulum stress. |
PIM2 |
| 5 |
30370255 |
10.15430/JCP.2018.23.3.109 |
2018 |
PIM Kinase as an Executional Target in Cancer. |
PIM2 |
| 6 |
28698206 |
10.1182/blood-2017-01-760702 |
2017 |
Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma. |
PIM2 |
| 7 |
28729093 |
10.1016/j.yexcr.2017.07.019 |
2017 |
PIM kinases 1, 2 and 3 in intracellular LIF signaling, proliferation and apoptosis in trophoblastic cells. |
PIM2 |
| 8 |
26764044 |
10.3109/10428194.2015.1124991 |
2016 |
Elevated PIM2 gene expression is associated with poor survival of patients with acute myeloid leukemia. |
PIM2 |
| 9 |
26824321 |
10.18632/oncotarget.7036 |
2016 |
Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma. |
PIM2 |
| 10 |
26340096 |
10.1371/journal.pone.0137210 |
2015 |
Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185. |
PIM2 |
| 11 |
26643319 |
10.1186/s12943-015-0477-z |
2015 |
Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. |
PIM2 |
| 12 |
24131033 |
10.1517/13543776.2014.848196 |
2014 |
Small molecule inhibitors of PIM1 kinase: July 2009 to February 2013 patent update. |
PIM2 |
| 13 |
24474669 |
10.1158/1078-0432.CCR-13-2062 |
2014 |
Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers. |
PIM2 |
| 14 |
25207815 |
10.1371/journal.pone.0106788 |
2014 |
Gene expression profiling identifies IRF4-associated molecular signatures in hematological malignancies. |
PIM2 |
| 15 |
23135987 |
10.1002/stem.1277 |
2013 |
TEL (ETV6)-AML1 (RUNX1) initiates self-renewing fetal pro-B cells in association with a transcriptional program shared with embryonic stem cells in mice. |
PIM2 |
| 16 |
23360755 |
10.1186/1756-8722-6-12 |
2013 |
Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice. |
PIM2 |
| 17 |
23752607 |
10.5604/17322693.1052449 |
2013 |
Expression of PIM-2 and NF-κB genes is increased in patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) and is associated with complete remission rate and overall survival. |
PIM2 |
| 18 |
24009772 |
10.1371/journal.pone.0074420 |
2013 |
Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts. |
PIM2 |
| 19 |
24900629 |
10.1021/ml400307j |
2013 |
Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors. |
PIM2 |
| 20 |
22722314 |
10.1038/bjc.2012.272 |
2012 |
PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma. |
PIM2 |
| 21 |
22808135 |
10.1371/journal.pone.0040332 |
2012 |
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma. |
PIM2 |
| 22 |
22843119 |
10.1007/s10059-012-0142-y |
2012 |
MYC and PIM2 co-expression in mouse bone marrow cells readily establishes permanent myeloid cell lines that can induce lethal myeloid sarcoma in vivo. |
PIM2 |
| 23 |
22955922 |
10.1182/blood-2012-02-412643 |
2012 |
Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma. |
PIM2 |
| 24 |
21273489 |
10.1126/science.1198946 |
2011 |
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. |
PIM2 |
| 25 |
21299464 |
10.3109/10428194.2011.553001 |
2011 |
Paired box gene 5 may modulate Proviral Integration of Moloney virus 2 gene and protein expression in mature B-cells. |
PIM2 |
| 26 |
21859846 |
10.1084/jem.20110846 |
2011 |
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma. |
PIM2 |
| 27 |
21937691 |
10.1182/blood-2011-03-344374 |
2011 |
PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma. |
PIM2 |
| 28 |
19965690 |
10.1182/blood-2009-07-233445 |
2010 |
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. |
PIM2 |
| 29 |
20215640 |
10.1182/blood-2009-03-210070 |
2010 |
Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model. |
PIM2 |
| 30 |
17289214 |
10.1016/j.jaad.2006.12.026 |
2007 |
New prognostic relevant factors in primary cutaneous diffuse large B-cell lymphomas. |
PIM2 |
| 31 |
17395733 |
10.1196/annals.1392.003 |
2007 |
Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene. |
PIM2 |
| 32 |
17696935 |
10.1111/j.1478-3231.2007.01542.x |
2007 |
Up-regulation of proproliferative genes and the ligand/receptor pair placental growth factor and vascular endothelial growth factor receptor 1 in hepatitis C cirrhosis. |
PIM2 |
| 33 |
15721354 |
10.1016/j.virol.2005.01.001 |
2005 |
Pim kinases are upregulated during Epstein-Barr virus infection and enhance EBNA2 activity. |
PIM2 |
| 34 |
16373702 |
10.1158/1535-7163.MCT-05-0146 |
2005 |
Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures. |
PIM2 |
| 35 |
15291354 |
10.1080/10428190310001641251 |
2004 |
Increased expression of the hPim-2 gene in human chronic lymphocytic leukemia and non-Hodgkin lymphoma. |
PIM2 |
| 36 |
15548703 |
10.1158/0008-5472.CAN-04-2284 |
2004 |
Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation. |
PIM2 |
| 37 |
12605034 |
10.1097/00019606-200303000-00005 |
2003 |
Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV. |
PIM2 |
| 38 |
12185366 |
10.1038/ng950 |
2002 |
High-throughput retroviral tagging to identify components of specific signaling pathways in cancer. |
PIM2 |
| 39 |
12200383 |
10.1182/blood-2002-01-0008 |
2002 |
A molecular compendium of genes expressed in multiple myeloma. |
PIM2 |
| 40 |
11313958 |
10.1038/sj.onc.1204090 |
2001 |
Runx2: a novel oncogenic effector revealed by in vivo complementation and retroviral tagging. |
PIM2 |
| 41 |
9804974 |
10.1016/s0167-4781(98)00185-7 |
1998 |
The human Pim-2 proto-oncogene and its testicular expression. |
PIM2 |
| 42 |
9294606 |
10.1038/sj.onc.1201288 |
1997 |
Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. |
PIM2 |
| 43 |
9401000 |
10.1038/sj.onc.1201670 |
1997 |
Pim1 cooperates with E2a-Pbx1 to facilitate the progression of thymic lymphomas in transgenic mice. |
PIM2 |
| 44 |
8786139 |
10.1006/geno.1996.0301 |
1996 |
Genomic structure and precise mapping of a thymic regulatory region on mouse chromosome 17 revealed by a c-myc transgene insertion. |
PIM2 |
| 45 |
7781606 |
10.1002/j.1460-2075.1995.tb07251.x |
1995 |
Proviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2. |
PIM2 |
| 46 |
7587098 |
10.1101/sqb.1994.059.01.049 |
1994 |
Mouse model systems to study multistep tumorigenesis. |
PIM2 |
Datasets
Models
