| 1 |
33297669 |
10.3324/haematol.2020.267294 |
2022 |
Phenogenomic heterogeneity of post-transplant plasmablastic lymphomas. |
NOTCH1 |
| 2 |
34624096 |
10.1182/blood.2020010405 |
2022 |
ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells. |
NOTCH1 |
| 3 |
34669156 |
10.1007/s11684-021-0877-y |
2022 |
Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 4 |
34814054 |
10.1016/j.tice.2021.101674 |
2022 |
Mechanism of IDH1-R132H mutation in T cell acute lymphoblastic leukemia mouse model via the Notch1 pathway. |
NOTCH1 |
| 5 |
34882582 |
10.1172/JCI153283 |
2022 |
Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma. |
NOTCH1 |
| 6 |
34937946 |
10.1038/s41586-021-04244-1 |
2022 |
Valine tRNA levels and availability regulate complex I assembly in leukaemia. |
NOTCH1 |
| 7 |
35014081 |
10.1002/ddr.21911 |
2022 |
Mitoquinone intravitreal injection ameliorates retinal ischemia-reperfusion injury in rats involving SIRT1/Notch1/NADPH axis. |
NOTCH1 |
| 8 |
35014928 |
10.1080/10428194.2021.2020779 |
2022 |
Up to 6.5 years (median 4 years) of follow-up of first-line ibrutinib in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma and high-risk genomic features: integrated analysis of two phase 3 studies. |
NOTCH1 |
| 9 |
35020836 |
10.1182/blood.2021012077 |
2022 |
Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL. |
NOTCH1 |
| 10 |
35106936 |
10.1002/cam4.4550 |
2022 |
SGK1 mutation status can further stratify patients with germinal center B-cell-like diffuse large B-cell lymphoma into different prognostic subgroups. |
NOTCH1 |
| 11 |
35129045 |
10.1080/10428194.2022.2032033 |
2022 |
Prognostic significance of <i>NOTCH1/FBXW7</i> mutations in pediatric T cell acute lymphoblastic leukemia: a study of minimal residual disease risk-directed CCLG-ALL 2008 treatment protocol. |
NOTCH1 |
| 12 |
35173274 |
10.1038/s41375-022-01516-1 |
2022 |
Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL. |
NOTCH1 |
| 13 |
35231988 |
10.3760/cma.j.issn.0253-2727.2022.01.005 |
2022 |
[Mutational spectrum and its prognostic significance in childhood acute lymphoblastic leukemia based on next-generation sequencing technology]. |
NOTCH1 |
| 14 |
35240234 |
10.1016/j.canlet.2022.215608 |
2022 |
DT7 peptide-modified lecithin nanoparticles co-loaded with γ-secretase inhibitor and dexamethasone efficiently inhibit T-cell acute lymphoblastic leukemia and reduce gastrointestinal toxicity. |
NOTCH1 |
| 15 |
35245453 |
10.1016/j.molcel.2022.02.015 |
2022 |
How to resist Notch-targeted T-leukemia therapy: Lineage- and MYC enhancer switch. |
NOTCH1 |
| 16 |
35279479 |
10.1016/j.imbio.2022.152205 |
2022 |
Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia. |
NOTCH1 |
| 17 |
35280829 |
10.3389/fonc.2022.811151 |
2022 |
Prognostic Significance of Comprehensive Gene Mutations and Clinical Characteristics in Adult T-Cell Acute Lymphoblastic Leukemia Based on Next-Generation Sequencing. |
NOTCH1 |
| 18 |
35280868 |
10.3389/fmed.2022.826705 |
2022 |
Case Report: Early Distant Metastatic Inflammatory Myofibroblastic Tumor Harboring <i>EML4-ALK</i> Fusion Gene: Study of Two Typical Cases and Review of Literature. |
NOTCH1 |
| 19 |
35300216 |
10.2147/JIR.S341355 |
2022 |
The Mutation of <i>BTG2</i> Gene Predicts a Poor Outcome in Primary Testicular Diffuse Large B-Cell Lymphoma. |
NOTCH1 |
| 20 |
35401501 |
10.3389/fimmu.2022.867443 |
2022 |
Monoallelic <i>Heb/Tcf12</i> Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia. |
NOTCH1 |
| 21 |
35589701 |
10.1038/s41467-022-30396-3 |
2022 |
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 22 |
35592856 |
10.3389/fmed.2022.808378 |
2022 |
A Somatic Mutation Signature Predicts the Best Overall Response to Anti-programmed Cell Death Protein-1 Treatment in Epidermal Growth Factor Receptor/Anaplastic Lymphoma Kinase-Negative Non-squamous Non-small Cell Lung Cancer. |
NOTCH1 |
| 23 |
35605191 |
10.1182/blood.2021015144 |
2022 |
NOTCH1 signaling during CD4+ T-cell activation alters transcription factor networks and enhances antigen responsiveness. |
NOTCH1 |
| 24 |
35680792 |
10.19746/j.cnki.issn.1009-2137.2022.03.006 |
2022 |
[Effect of Curcumin on Apoptosis of Acute T-Lymphoblastic Leukemia Cells induced by UMI-77 and Its Related Mechanism]. |
NOTCH1 |
| 25 |
35681778 |
10.3390/cancers14112799 |
2022 |
The Role of NOTCH1, GATA3, and c-MYC in T Cell Non-Hodgkin Lymphomas. |
NOTCH1 |
| 26 |
35685993 |
10.21147/j.issn.1000-9604.2022.02.03 |
2022 |
Genomic landscape of T-cell lymphoblastic lymphoma. |
NOTCH1 |
| 27 |
35734596 |
10.3389/fonc.2022.846573 |
2022 |
The Clinical Characteristics and Prognosis of AYA and Older Adult ETP-ALL/LBL: A Real-World Multicenter Study in China. |
NOTCH1 |
| 28 |
35767640 |
10.1073/pnas.2118529119 |
2022 |
Early expression of mature αβ TCR in CD4<sup>-</sup>CD8<sup>-</sup> T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. |
NOTCH1 |
| 29 |
35768390 |
10.3760/cma.j.cn112137-20211025-02358 |
2022 |
[Characteristics and prognostic effects of NOTCH1/FBXW7 gene mutations in T-cell acute lymphoblastic leukemia patients]. |
NOTCH1 |
| 30 |
35774848 |
10.1155/2022/3276925 |
2022 |
Identification of CXCR4 Upregulation in Diffuse Large B-Cell Lymphoma Associated with Prognostic Significance and Clinicopathological Characteristics. |
NOTCH1 |
| 31 |
35829664 |
10.1111/bjh.18352 |
2022 |
Clonally unrelated Richter syndrome are truly de novo diffuse large B-cell lymphomas with a mutational profile reminiscent of clonally related Richter syndrome. |
NOTCH1 |
| 32 |
35852337 |
10.1128/spectrum.01478-22 |
2022 |
BET-Independent Murine Leukemia Virus Integration Is Retargeted <i>In Vivo</i> and Selects Distinct Genomic Elements for Lymphomagenesis. |
NOTCH1 |
| 33 |
35910501 |
10.6004/jadpro.2022.13.5.7 |
2022 |
An Approach to Diagnosis of Richter Transformation in Chronic Lymphocytic Leukemia. |
NOTCH1 |
| 34 |
35915142 |
10.1038/s41375-022-01651-9 |
2022 |
Inhibition of the m<sup>6</sup>A reader IGF2BP2 as a strategy against T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 35 |
36000950 |
10.1002/pbc.29926 |
2022 |
Diverse mutations and structural variations contribute to Notch signaling deregulation in paediatric T-cell lymphoblastic lymphoma. |
NOTCH1 |
| 36 |
36090975 |
10.3389/fimmu.2022.987298 |
2022 |
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. |
NOTCH1 |
| 37 |
32273478 |
10.3324/haematol.2020.251579 |
2021 |
Genetic lesions in MYC and STAT3 drive oncogenic transcription factor overexpression in plasmablastic lymphoma. |
NOTCH1 |
| 38 |
32327503 |
10.3324/haematol.2019.238766 |
2021 |
Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target. |
NOTCH1 |
| 39 |
32382081 |
10.1038/s41375-020-0845-6 |
2021 |
SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 40 |
32415821 |
10.17305/bjbms.2020.4687 |
2021 |
Progress in research on childhood T-cell acute lymphocytic leukemia, Notch1 signaling pathway, and its inhibitors: A review. |
NOTCH1 |
| 41 |
32733009 |
10.1038/s41375-020-0999-2 |
2021 |
Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination. |
NOTCH1 |
| 42 |
32812017 |
10.1182/blood.2020006996 |
2021 |
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 43 |
33068240 |
10.1007/s11845-020-02386-1 |
2021 |
Biclonal lymphoproliferative disorders: another association with NOTCH1-mutated chronic lymphocytic leukaemias. |
NOTCH1 |
| 44 |
33152759 |
10.1182/blood.2020005381 |
2021 |
Integrative genomic analysis of pediatric T-cell lymphoblastic lymphoma reveals candidates of clinical significance. |
NOTCH1 |
| 45 |
33191568 |
10.1002/onco.13595 |
2021 |
More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment. |
NOTCH1 |
| 46 |
33227818 |
10.1182/blood.2019004547 |
2021 |
Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL. |
NOTCH1 |
| 47 |
33310759 |
10.26508/lsa.202000794 |
2021 |
Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis. |
NOTCH1 |
| 48 |
33314742 |
10.1002/1878-0261.12877 |
2021 |
Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia. |
NOTCH1 |
| 49 |
33316538 |
10.1016/j.neo.2020.11.010 |
2021 |
U-RT1 - A new model for Richter transformation. |
NOTCH1 |
| 50 |
33407740 |
10.1186/s13045-020-01015-9 |
2021 |
Targeting oncogenic Notch signaling with SERCA inhibitors. |
NOTCH1 |
| 51 |
33436855 |
10.1038/s41598-020-80613-6 |
2021 |
Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 52 |
33458694 |
10.1158/2643-3230.BCD-20-0201 |
2021 |
A Tumor Suppressor Enhancer of <i>PTEN</i> in T-cell development and leukemia. |
NOTCH1 |
| 53 |
33479306 |
10.1038/s41598-020-80376-0 |
2021 |
Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma. |
NOTCH1 |
| 54 |
33526873 |
10.1038/s41379-021-00739-4 |
2021 |
Clinical, immunophenotypic and genomic findings of NK lymphoblastic leukemia: a study from the Bone Marrow Pathology Group. |
NOTCH1 |
| 55 |
33538669 |
10.2174/1389450122666210203192752 |
2021 |
Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia. |
NOTCH1 |
| 56 |
33538798 |
10.1182/blood.2020005734 |
2021 |
Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. |
NOTCH1 |
| 57 |
33569430 |
10.21037/atm-20-7574 |
2021 |
Molecular profiling of Chinese systemic anaplastic large cell lymphoma patients: novel evidence of genetic heterogeneity. |
NOTCH1 |
| 58 |
33570635 |
10.1182/bloodadvances.2020002995 |
2021 |
Notch activation is pervasive in SMZL and uncommon in DLBCL: implications for Notch signaling in B-cell tumors. |
NOTCH1 |
| 59 |
33571115 |
10.1126/sciadv.abc9781 |
2021 |
NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia. |
NOTCH1 |
| 60 |
33578108 |
10.1016/j.jbior.2021.100788 |
2021 |
Mutations that collaborate with IL-7Ra signaling pathways to drive ALL. |
NOTCH1 |
| 61 |
33611795 |
10.1002/gcc.22943 |
2021 |
MYB rearrangements and over-expression in T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 62 |
33615197 |
10.1016/j.isci.2021.102089 |
2021 |
Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways. |
NOTCH1 |
| 63 |
33634864 |
10.1002/ijc.33527 |
2021 |
Deleterious point mutations in T-cell acute lymphoblastic leukemia: Mechanistic insights into leukemogenesis. |
NOTCH1 |
| 64 |
33775465 |
10.1016/j.blre.2021.100824 |
2021 |
Revisiting Richter transformation in the era of novel CLL agents. |
NOTCH1 |
| 65 |
33777778 |
10.3389/fonc.2021.628807 |
2021 |
Mutational Profile and Clonal Evolution of Relapsed/Refractory Diffuse Large B-Cell Lymphoma. |
NOTCH1 |
| 66 |
33858050 |
10.3760/cma.j.issn.0253-2727.2021.02.014 |
2021 |
[The role and research progress of NOTCH1 in T-cell acute lymphoblastic leukemia]. |
NOTCH1 |
| 67 |
33876224 |
10.1182/blood.2020008955 |
2021 |
A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia. |
NOTCH1 |
| 68 |
33925883 |
10.3390/ijms22094502 |
2021 |
The New Therapeutic Strategies in Pediatric T-Cell Acute Lymphoblastic Leukemia. |
NOTCH1 |
| 69 |
33941203 |
10.1186/s13045-021-01068-4 |
2021 |
Oncogenetic landscape and clinical impact of IDH1 and IDH2 mutations in T-ALL. |
NOTCH1 |
| 70 |
33942287 |
10.1111/bjh.17310 |
2021 |
Current and emerging therapeutic approaches for T-cell acute lymphoblastic leukaemia. |
NOTCH1 |
| 71 |
33947863 |
10.1038/s41467-021-22787-9 |
2021 |
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures. |
NOTCH1 |
| 72 |
33972504 |
10.1038/s41408-021-00477-5 |
2021 |
Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome. |
NOTCH1 |
| 73 |
34035082 |
10.1158/0008-5472.CAN-20-2823 |
2021 |
Whole-Exome Sequencing of Radiation-Induced Thymic Lymphoma in Mouse Models Identifies Notch1 Activation as a Driver of p53 Wild-Type Lymphoma. |
NOTCH1 |
| 74 |
34080325 |
10.1002/cam4.4024 |
2021 |
The genomic landscape of teenage and young adult T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 75 |
34167562 |
10.1186/s13045-021-01114-1 |
2021 |
PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia. |
NOTCH1 |
| 76 |
34188174 |
10.1038/s42003-021-02330-8 |
2021 |
NOTCH-ing up nucleotide metabolism in T-cell acute lymphoblastic leukemia. |
NOTCH1 |
| 77 |
34203994 |
10.3390/cancers13123005 |
2021 |
<i>DLX</i> Genes: Roles in Development and Cancer. |
NOTCH1 |
| 78 |
34218589 |
10.3760/cma.j.issn.0253-2727.2021.05.015 |
2021 |
[The characteristics and prognostic impact of NOTCH1/FBXW7 mutation and CDKN2A/B deletion in adult T-cell acute lymphoblastic leukemia patients]. |
NOTCH1 |
| 79 |
34223928 |
10.1007/s00109-021-02101-2 |
2021 |
CARMA1 is required for Notch1-induced NF-κB activation in SIL-TAL1-negative T cell acute lymphoblastic leukemia. |
NOTCH1 |
| 80 |
34256839 |
10.1186/s40164-021-00232-3 |
2021 |
Progress in molecular feature of smoldering mantle cell lymphoma. |
NOTCH1 |
| 81 |
34376672 |
10.1038/s41467-021-25101-9 |
2021 |
Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. |
NOTCH1 |
| 82 |
34407842 |
10.1186/s13046-021-02071-w |
2021 |
SIRT1 regulates the phosphorylation and degradation of P27 by deacetylating CDK2 to promote T-cell acute lymphoblastic leukemia progression. |
NOTCH1 |
| 83 |
34440292 |
10.3390/genes12081118 |
2021 |
T-Cell Acute Lymphoblastic Leukemia: Biomarkers and Their Clinical Usefulness. |
NOTCH1 |
| 84 |
34506616 |
10.1371/journal.pone.0257353 |
2021 |
Genomic mutation profile in progressive chronic lymphocytic leukemia patients prior to first-line chemoimmunotherapy with FCR and rituximab maintenance (REM). |
NOTCH1 |
| 85 |
34514345 |
10.1097/HS9.0000000000000641 |
2021 |
Toward Pediatric T Lymphoblastic Lymphoma Stratification Based on Minimal Disseminated Disease and <i>NOTCH1/FBXW7</i> Status. |
NOTCH1 |
| 86 |
34573936 |
10.3390/diagnostics11091594 |
2021 |
Prognostic Role of Minimal Disseminated Disease and <i>NOTCH1/FBXW7</i> Mutational Status in Children with Lymphoblastic Lymphoma: The AIEOP Experience. |
NOTCH1 |
| 87 |
34680290 |
10.3390/cancers13205141 |
2021 |
Richter Transformation in Chronic Lymphocytic Leukemia: Update in the Era of Novel Agents. |
NOTCH1 |
| 88 |
34698884 |
10.1007/s00018-021-03979-4 |
2021 |
MicroRNA-34a: the bad guy in age-related vascular diseases. |
NOTCH1 |
| 89 |
34735923 |
10.1016/j.imbio.2021.152149 |
2021 |
Upregulation of leukemia-induced non-coding activator RNA (LUNAR1) predicts poor outcome in pediatric T-acute lymphoblastic leukemia. |
NOTCH1 |
| 90 |
34739844 |
10.1016/j.ccell.2021.10.006 |
2021 |
Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL. |
NOTCH1 |
| 91 |
34753401 |
10.1080/16078454.2021.1997197 |
2021 |
Circ_0000745 regulates NOTCH1-mediated cell proliferation and apoptosis in pediatric T-cell acute lymphoblastic leukemia through adsorbing miR-193b-3p. |
NOTCH1 |
| 92 |
34771656 |
10.3390/cancers13215493 |
2021 |
High Expression of <i>PPM1D</i> Induces Tumors Phenotypically Similar to <i>TP53</i> Loss-of-Function Mutations in Mice. |
NOTCH1 |
| 93 |
34956871 |
10.3389/fonc.2021.746577 |
2021 |
Clinical Features and Prognostic Significance of <i>NOTCH1</i> Mutations in Diffuse Large B-Cell Lymphoma. |
NOTCH1 |
| 94 |
34956898 |
10.3389/fonc.2021.780085 |
2021 |
Treatment Approaches to Chronic Lymphocytic Leukemia With High-Risk Molecular Features. |
NOTCH1 |
| 95 |
35008340 |
10.3390/cancers14010176 |
2021 |
Recent Advances in the Genetic of MALT Lymphomas. |
NOTCH1 |
| 96 |
35111674 |
10.3389/fonc.2021.790481 |
2021 |
Mutations in <i>JAK/STAT</i> and <i>NOTCH1</i> Genes Are Enriched in Post-Transplant Lymphoproliferative Disorders. |
NOTCH1 |
| 97 |
29313423 |
10.1080/21541248.2018.1423851 |
2020 |
Rho guanosine nucleotide exchange factors are not such bad guys after all in cancer<sup>a</sup>. |
NOTCH1 |
| 98 |
31467126 |
10.3324/haematol.2019.217687 |
2020 |
Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts. |
NOTCH1 |
| 99 |
31570389 |
10.1101/cshperspect.a035246 |
2020 |
The Genetics and Mechanisms of T-Cell Acute Lymphoblastic Leukemia. |
NOTCH1 |
| 100 |
31586130 |
10.1038/s41388-019-1042-9 |
2020 |
NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling. |
NOTCH1 |
Datasets
Models
