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# pmid doi year title Hugo_Symbol
1 34337566 10.1016/j.xcrm.2021.100350 2022 ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors. HRAS
2 34341476 10.1038/s10038-021-00965-3 2022 PAX3/7-FOXO1 fusion-negative alveolar rhabdomyosarcoma in Schuurs-Hoeijmakers syndrome. HRAS
3 35092381 10.31557/APJCP.2022.23.1.131 2022 Correlation between Programmed Death Ligand-1(PD-L1) Expression and Driver Gene Mutations in Non-Small Cell Lung Carcinoma- Adenocarcinoma Phenotype. HRAS
4 35192832 10.1016/j.scitotenv.2022.153990 2022 Effects of gestational exposure to bisphenol A on the hepatic transcriptome and lipidome of rat dams: Intergenerational comparison of effects in the offspring. HRAS
5 35363510 10.1200/JCO.21.02840 2022 Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial. HRAS
6 35674396 10.1093/bioinformatics/btac380 2022 Prediction of Allosteric Communication Pathways in Proteins. HRAS
7 35981360 10.19746/j.cnki.issn.1009-2137.2022.04.011 2022 [The Effect of KRAS on Proliferation and Apoptosis of T-ALL Cell Lines]. HRAS
8 32147503 10.1016/j.jid.2020.02.019 2021 Recurrent Oncogenic JAK and STAT Alterations in Cutaneous CD30-Positive Lymphoproliferative Disorders. HRAS
9 33016928 10.1172/JCI139080 2021 Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma. HRAS
10 33297669 10.3324/haematol.2020.267294 2021 Phenogenomic heterogeneity of post-transplant plasmablastic lymphomas. HRAS
11 33397922 10.1038/s41467-020-20255-4 2021 A RAC-GEF network critical for early intestinal tumourigenesis. HRAS
12 33512434 10.1182/blood.2020009082 2021 Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors. HRAS
13 33750196 10.1200/JCO.20.02903 2021 Tipifarnib in Head and Neck Squamous Cell Carcinoma With <i>HRAS</i> Mutations. HRAS
14 34302028 10.1038/s41598-021-94566-x 2021 Development of thymic tumor in [LSL:Kras<sup>G12D</sup>; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis. HRAS
15 30087949 10.1210/js.2018-00132 2020 Synchronous Independent Papillary Thyroid Carcinomas in Struma Ovarii and the Thyroid Gland With Different <i>RAS</i> Mutations. HRAS
16 30946933 10.1016/j.humpath.2019.03.004 2020 The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement. HRAS
17 32188628 10.1136/jclinpath-2020-206461 2020 Transcriptome complexity in intravascular NK/T-cell lymphoma. HRAS
18 32620621 10.21873/anticanres.14371 2020 Anti-tumor Properties of <i>Picrasma quassioides</i> Extracts in H-Ras<sup>G12V</sup> Liver Cancer Are Mediated Through ROS-dependent Mitochondrial Dysfunction. HRAS
19 29636358 10.1158/1078-0432.CCR-17-2452 2019 Resistance Mechanisms to Targeted Therapies in <i>ROS1</i><sup>+</sup> and <i>ALK</i><sup>+</sup> Non-small Cell Lung Cancer. HRAS
20 29661787 10.1182/blood-2018-01-827949 2019 Thromboembolism in acute lymphoblastic leukemia: results of NOPHO ALL2008 protocol treatment in patients aged 1 to 45 years. HRAS
21 29950132 10.1080/15548627.2018.1466013 2019 Role of the MAPK/cJun NH<sub>2</sub>-terminal kinase signaling pathway in starvation-induced autophagy. HRAS
22 30875092 10.1002/bem.22177 2019 Carcinogenicity of intermediate frequency magnetic field in Tg.rasH2 mice. HRAS
23 31199785 10.1371/journal.pgen.1008168 2019 Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias. HRAS
24 27034005 10.18632/oncotarget.8427 2018 Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. HRAS
25 27102345 10.1038/modpathol.2016.79 2018 Comprehensive genomic profiling of orbital and ocular adnexal lymphomas identifies frequent alterations in MYD88 and chromatin modifiers: new routes to targeted therapies. HRAS
26 27484103 10.1080/07391102.2016.1188417 2018 An integrated approach of network-based systems biology, molecular docking, and molecular dynamics approach to unravel the role of existing antiviral molecules against AIDS-associated cancer. HRAS
27 28262675 10.1038/ncomms14581 2018 Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene. HRAS
28 29923908 10.1097/DAD.0000000000001014 2018 ALK Rearrangements Are Infrequent in Cellular Blue Nevus and Deep Penetrating Nevus. HRAS
29 30257940 10.1073/pnas.1721678115 2018 PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice. HRAS
30 26675036 10.1177/1066896915622261 2017 Epithelial-Myoepithelial Carcinoma of the Salivary Gland Harboring HRAS Codon 61 Mutations With Lung Metastasis. HRAS
31 26873340 10.1177/1066896916630375 2017 Spitz Tumors: Comparison of Histological Features in Relationship to Immunohistochemical Staining for ALK and NTRK1. HRAS
32 27017489 10.1007/s00204-016-1696-9 2017 Twenty-six-week oral carcinogenicity study of 3-monochloropropane-1,2-diol in CB6F1-rasH2 transgenic mice. HRAS
33 27055865 10.1038/leu.2016.40 2017 Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis. HRAS
34 27488117 10.1007/s13277-016-5283-8 2017 IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells. HRAS
35 27696251 10.1007/s12020-016-1080-9 2017 Targeted next-generation sequencing for TP53, RAS, BRAF, ALK and NF1 mutations in anaplastic thyroid cancer. HRAS
36 28235199 10.1016/j.cell.2017.02.006 2017 Multivalent Small-Molecule Pan-RAS Inhibitors. HRAS
37 28425994 10.1038/nature22056 2017 Modulating the therapeutic response of tumours to dietary serine and glycine starvation. HRAS
38 26399548 10.1038/ncomms9477 2016 Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma. HRAS
39 26507119 10.1080/15592294.2015.1110672 2016 Epigenetic instability at imprinting control regions in a Kras(G12D)-induced T-cell neoplasm. HRAS
40 26855057 10.1016/j.ejmg.2016.01.003 2016 Acute lymphoblastic leukemia in the context of RASopathies. HRAS
41 27013922 10.2174/1389202916666151014221954 2016 Genetics of Bladder Malignant Tumors in Childhood. HRAS
42 25371176 10.1038/leu.2014.315 2015 Wild-type KRAS inhibits oncogenic KRAS-induced T-ALL in mice. HRAS
43 25387078 10.3390/ijms151120500 2015 Multiple mechanisms mediate resistance to sorafenib in urothelial cancer. HRAS
44 25602801 10.1097/PAS.0000000000000387 2015 Clinical, histopathologic, and genomic features of Spitz tumors with ALK fusions. HRAS
45 23751074 10.1111/pcmr.12129 2014 Identification of anaplastic lymphoma kinase break points and oncogenic mutation profiles in acral/mucosal melanomas. HRAS
46 24505083 10.1182/blood-2013-01-477620 2014 Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy. HRAS
47 22575864 10.1038/modpathol.2012.73 2013 Thyroid carcinoma-associated genetic mutations also occur in thyroid lymphomas. HRAS
48 22684892 10.1002/ijc.27668 2013 Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis. HRAS
49 22792269 10.1371/journal.pone.0040302 2013 The role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancer. HRAS
50 22976127 10.1038/leu.2012.251 2013 Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals. HRAS
51 23183424 10.1038/leu.2012.316 2013 Differential roles of Kras and Pten in murine leukemogenesis. HRAS
52 23392229 10.1097/JTO.0b013e318283558e 2013 Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma. HRAS
53 23673656 10.1074/jbc.M113.475376 2013 Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation. HRAS
54 21045156 10.1158/0008-5472.CAN-10-1568 2011 Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling. HRAS
55 20194733 10.1073/pnas.1001064107 2010 Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents. HRAS
56 18827450 10.2131/jts.33.493 2009 Carcinogenic comparative study on rasH2 mice produced by two breeding facilities. HRAS
57 19066392 10.1182/blood-2008-01-134262 2009 Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation. HRAS
58 19296721 10.1371/journal.pbio.1000059 2009 Oncogenic Kras initiates leukemia in hematopoietic stem cells. HRAS
59 19543317 10.1038/onc.2009.165 2009 BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases. HRAS
60 19765110 10.1111/j.1365-2613.2009.00667.x 2009 Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways. HRAS
61 16923573 10.1080/10428190600565925 2007 Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutations. HRAS
62 16969076 10.4161/cbt.5.8.3251 2007 Recurrent KRAS codon 146 mutations in human colorectal cancer. HRAS
63 17251932 10.1038/nature05541 2007 Restoration of p53 function leads to tumour regression in vivo. HRAS
64 17483702 10.1097/MPH.0b013e3180547136 2007 Leukemia in Cardio-facio-cutaneous (CFC) syndrome: a patient with a germline mutation in BRAF proto-oncogene. HRAS
65 12393503 10.1182/blood-2002-08-2434 2003 Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas. HRAS
66 12650030 2003 [Clinical importance of semi-quantitative monitoring of lymphomas using the comparative polymerase chain reaction]. HRAS
67 12970747 10.1038/sj.onc.1206766 2003 Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival. HRAS
68 11748353 10.3346/jkms.2001.16.6.731 2002 Expressions of p53 and p21 in primary gastric lymphomas. HRAS
69 12134164 10.1038/ncb833 2002 Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. HRAS
70 11351252 10.3892/ijo.18.6.1207 2001 Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability. HRAS
71 10634643 10.1016/s0145-2126(99)00157-5 2000 Overexpression of Ras, Raf and L-myc but not Bcl-2 family proteins is linked with resistance to TCR-mediated apoptosis and tumorigenesis in thymic lymphomas from TCR transgenic mice. HRAS
72 10730886 2000 Monitoring of residual disease in non-Hodgkin's lymphomas by quantitative PCR (preliminary report). HRAS
73 10769750 10.2144/00284st08 2000 Optimized multiplex IgH/ras PCR: a tool for quantitative monitoring of B-lymphoproliferative disorders. HRAS
74 9563642 10.1016/s0304-3835(97)00530-2 1998 MNNG-transformed Bloom syndrome B-lymphoblastoids for the detection of Hodgkin's lymphoma-associated antigen in 2D Westerns. HRAS
75 8940017 10.1074/jbc.271.48.30499 1997 Human type II Fcgamma receptors inhibit B cell activation by interacting with the p21(ras)-dependent pathway. HRAS
76 8970991 10.1128/JVI.70.12.8653-8659.1996 1997 Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. HRAS
77 9052860 10.1016/s0165-2478(96)02655-7 1997 Integration of activatory and inhibitory signals in human B-cells. HRAS
78 9111865 10.1016/s0065-230x(08)60098-6 1997 Functional aspects of apoptosis in hematopoiesis and consequences of failure. HRAS
79 8816388 1996 Activation of the Ras signaling pathway by the CD40 receptor. HRAS
80 7547984 10.1021/bi00038a037 1995 Burkitt lymphoma Daudi cells contain two distinct farnesyltransferases with different divalent cation requirements. HRAS
81 7761357 10.1007/s002920050084 1995 [Apoptosis and cell proliferation in HHV-6 infections. Regulatory mechanisms of p53/bcl-2/ras interactions]. HRAS
82 7784061 1995 TTF, a gene encoding a novel small G protein, fuses to the lymphoma-associated LAZ3 gene by t(3;4) chromosomal translocation. HRAS
83 8112727 10.1002/hon.2900110303 1994 Association between ATL and non-hematopoietic neoplasms. HRAS
84 1295465 1993 The expression of the ras p21 oncoprotein in the bone marrow smears of children with acute leukemia. HRAS
85 8505202 1993 Investigation of the role of the ras protooncogene point mutation in human uveal melanomas. HRAS
86 1313398 10.1002/ijc.2910500610 1992 Serum oncoproteins and growth factors in asbestosis and silicosis patients. HRAS
87 1373069 10.3109/08880019209006397 1992 Oncogene RNA expression in three human lymphoblastic leukemia cell lines lymphocytes. HRAS
88 1628649 10.1111/j.1432-1033.1992.tb17039.x 1992 Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells. HRAS
89 1737360 1992 Chemically induced forestomach papillomas in transgenic mice carry mutant human c-Ha-ras transgenes. HRAS
90 1746900 1992 Implication of the ras and myc oncoproteins in the pathogenesis of mycosis fungoides. HRAS
91 1773791 10.1289/ehp.919319 1992 ras activation in human tumors and in animal model systems. HRAS
92 2040694 10.1172/JCI115234 1991 The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia. HRAS
93 1699752 10.1507/endocrj1954.37.247 1990 Tumor markers and oncogene expression in thyroid cancer using biochemical and immunohistochemical studies. HRAS
94 1976194 10.1016/0140-6736(90)93302-6 1990 Co-expression of N-ras p21 and C-erbB-2 (neu) oncogene products by common ALL antigen-positive aggressive diffuse lymphoma. HRAS
95 2183888 1990 The pattern of mutational involvement of RAS genes in human hematologic malignancies determined by DNA amplification and direct sequencing. HRAS
96 2687507 1990 [Studies on association between the ATL and the development of multiple malignant neoplasms--analysis of 1171 cases of hematological malignancies during the past 24 years]. HRAS
97 2511175 10.1111/j.1349-7006.1989.tb01701.x 1989 Increased expression of ras genes in non-Hodgkin's lymphomas is not associated with oncogenic activation of those genes by point mutation. HRAS
98 2563124 10.1016/s0140-6736(89)91233-6 1989 Multiple primary malignant neoplasms in patients with adult T-cell leukaemia. HRAS
99 2681441 10.1002/stem.5530070603 1989 ras mutations in human leukemia and related disorders. HRAS
100 3065747 10.1016/S0344-0338(88)80050-5 1989 Interaction between transforming growth factor-alpha and c-Ha-ras p21 in progression of human gastric carcinoma. HRAS