| 1 |
33870156 |
10.1016/j.jhepr.2021.100250 |
2022 |
Genetic or pharmacological reduction of cholangiocyte senescence improves inflammation and fibrosis in the <i>Mdr2</i> <sup><i>-/-</i></sup> mouse. |
CASP8 |
| 2 |
34276918 |
10.4084/MJHID.2021.049 |
2022 |
Crocin Promotes Apoptosis in Human EBV-Transformed B-Lymphocyte via Intrinsic Pathway. |
CASP8 |
| 3 |
34302634 |
10.1007/s13258-021-01142-8 |
2022 |
Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLAR<sub>L</sub> downregulation in Caki-1 cells. |
CASP8 |
| 4 |
34853447 |
10.1038/s41418-021-00908-7 |
2022 |
Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1. |
CASP8 |
| 5 |
35178927 |
10.19540/j.cnki.cjcmm.20210902.701 |
2022 |
[Molecular mechanism of Ganoderma against gastric cancer based on network pharmacology and experimental test]. |
CASP8 |
| 6 |
35628538 |
10.3390/ijms23105721 |
2022 |
Therapeutic Potential of Pretreatment with Exosomes Derived from Stem Cells from the Apical Papilla against Cisplatin-Induced Acute Kidney Injury. |
CASP8 |
| 7 |
31954371 |
10.1016/j.redox.2019.101403 |
2021 |
Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP. |
CASP8 |
| 8 |
32575162 |
10.1002/cbf.3569 |
2021 |
Characterization of antiapoptotic microRNAs in primary Sjögren's syndrome. |
CASP8 |
| 9 |
33039058 |
10.1016/S1875-5364(20)60019-X |
2021 |
Dracocephalum palmatum Stephan extract induces apoptosis in human prostate cancer cells via the caspase-8-mediated extrinsic pathway. |
CASP8 |
| 10 |
33162537 |
10.11406/rinketsu.61.1365 |
2021 |
[Lymphoproliferative disorders and inborn errors of immunity]. |
CASP8 |
| 11 |
33241658 |
10.1111/jcmm.16117 |
2021 |
Anti-coronavirus disease 2019 (COVID-19) targets and mechanisms of puerarin. |
CASP8 |
| 12 |
33297339 |
10.3390/nu12123755 |
2021 |
Gene Expression Alterations Associated with Oleuropein-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Triple-Negative Breast Cancer Cells. |
CASP8 |
| 13 |
33356695 |
10.1080/10408363.2020.1855623 |
2021 |
Immunologic evaluation and genetic defects of apoptosis in patients with autoimmune lymphoproliferative syndrome (ALPS). |
CASP8 |
| 14 |
33913583 |
10.1002/cbin.11619 |
2021 |
Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway. |
CASP8 |
| 15 |
33922439 |
10.3390/cells10050987 |
2021 |
Targeting Cutaneous T-Cell Lymphoma Cells by Ingenol Mebutate (PEP005) Correlates with PKCδ Activation, ROS Induction as Well as Downregulation of XIAP and c-FLIP. |
CASP8 |
| 16 |
33974882 |
10.1016/j.ejphar.2021.174167 |
2021 |
Effects of trans-resveratrol on type 1 diabetes-induced up-regulation of apoptosis and mitogen-activated protein kinase signaling in retinal pigment epithelium of Dark Agouti rats. |
CASP8 |
| 17 |
33995372 |
10.3389/fimmu.2021.656356 |
2021 |
Next Generation Sequencing for Detecting Somatic <i>FAS</i> Mutations in Patients With Autoimmune Lymphoproliferative Syndrome. |
CASP8 |
| 18 |
34627429 |
10.19746/j.cnki.issn.1009-2137.2021.05.018 |
2021 |
[Relationships between CASP8, Fas Gene Polymorphisms and the Prognosis of Patients with Non-Hodgkin's Lymphoma in Han Nationality]. |
CASP8 |
| 19 |
34945004 |
10.3390/cancers13246384 |
2021 |
Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel. |
CASP8 |
| 20 |
30859901 |
10.1080/15548627.2019.1591672 |
2020 |
Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation. |
CASP8 |
| 21 |
30990357 |
10.1080/15548627.2019.1607694 |
2020 |
Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells. |
CASP8 |
| 22 |
31220671 |
10.1016/j.bioorg.2019.103053 |
2020 |
Protective effect of hypoxylonol C and 4,5,4',5'-tetrahydroxy-1,1'-binaphthyl isolated from Annulohypoxylon annulatum against streptozotocin-induced damage in INS-1 cells. |
CASP8 |
| 23 |
31730868 |
10.1016/j.lfs.2019.117038 |
2020 |
Effect of maternal omega-3 fatty acids and vitamin E supplementation on placental apoptotic markers in rat model of early and late onset preeclampsia. |
CASP8 |
| 24 |
31752870 |
10.1186/s12917-019-2167-3 |
2020 |
Effects of prostaglandin F<sub>2α</sub> (PGF<sub>2α</sub>) on cell-death pathways in the bovine corpus luteum (CL). |
CASP8 |
| 25 |
31908105 |
10.1111/cas.14296 |
2020 |
Efficient recruitment of c-FLIP<sub>L</sub> to the death-inducing signaling complex leads to Fas resistance in natural killer-cell lymphoma. |
CASP8 |
| 26 |
31974619 |
10.3892/mmr.2019.10873 |
2020 |
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells. |
CASP8 |
| 27 |
32075108 |
10.3390/ijms21041298 |
2020 |
C5, A Cassaine Diterpenoid Amine, Induces Apoptosis via the Extrinsic Pathways in Human Lung Cancer Cells and Human Lymphoma Cells. |
CASP8 |
| 28 |
29755111 |
10.1038/s41417-018-0022-5 |
2019 |
Genomic landscape and prognostic analysis of mantle cell lymphoma. |
CASP8 |
| 29 |
29891925 |
10.1038/s41598-018-27106-9 |
2019 |
Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway. |
CASP8 |
| 30 |
30061179 |
10.1042/BSR20180391 |
2019 |
<i>In vivo</i> and <i>in vitro</i> effects of hyperplasia suppressor gene on the proliferation and apoptosis of lung adenocarcinoma A549 cells. |
CASP8 |
| 31 |
30175514 |
10.1111/nep.13487 |
2019 |
Loss of receptor interacting protein kinases 3 and caspase-8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia-reperfusion injury. |
CASP8 |
| 32 |
31810928 |
10.21873/anticanres.13878 |
2019 |
Evaluation of Combination Treatment Effect With TRAIL-secreting Mesenchymal Stem Cells and Compound C Against Glioblastoma. |
CASP8 |
| 33 |
28199208 |
10.2741/4549 |
2018 |
Macrophage migration inhibitory factor siRNA inhibits hepatic metastases of colorectal cancer cells. |
CASP8 |
| 34 |
28427190 |
10.18632/oncotarget.15843 |
2018 |
Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells. |
CASP8 |
| 35 |
28643758 |
10.4103/0973-1482.176172 |
2018 |
Effects of EF-24, RAD001, and paclitaxel on the expression profiles of apoptotic and anti-apoptotic genes. |
CASP8 |
| 36 |
28765878 |
10.3892/ijmm.2017.3081 |
2018 |
Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway. |
CASP8 |
| 37 |
28972304 |
10.1002/1878-0261.12140 |
2018 |
DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells. |
CASP8 |
| 38 |
29617412 |
10.1371/journal.pone.0195116 |
2018 |
Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells. |
CASP8 |
| 39 |
29966986 |
10.1016/j.biopha.2018.06.164 |
2018 |
In vitro combinatorial anti-proliferative and immunosuppressive effects of Brucea javanica extract with CX-4945 and imatinib in human T-cell acute lymphoblastic leukemia cells. |
CASP8 |
| 40 |
30111413 |
10.7534/j.issn.1009-2137.2018.04.025 |
2018 |
[Apoptosis of Murine T-Cell Lymphoma EL4 Cells Induced by Murine Cytomegalovirus and Its Mechanism]. |
CASP8 |
| 41 |
26905515 |
10.1007/s00296-016-3443-1 |
2017 |
Fas/FasL, Bcl2 and Caspase-8 gene polymorphisms in Chinese patients with rheumatoid arthritis. |
CASP8 |
| 42 |
27176505 |
10.3892/ijo.2016.3518 |
2017 |
The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells. |
CASP8 |
| 43 |
27193732 |
10.2131/jts.41.403 |
2017 |
Ochratoxin A mediates MAPK activation, modulates IL-2 and TNF-α mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells. |
CASP8 |
| 44 |
27391025 |
10.1371/journal.pone.0158987 |
2017 |
The Interaction of CD154 with the α5β1 Integrin Inhibits Fas-Induced T Cell Death. |
CASP8 |
| 45 |
27678524 |
10.1016/j.taap.2016.09.021 |
2017 |
A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. |
CASP8 |
| 46 |
27868169 |
10.1007/s11010-016-2883-y |
2017 |
Articulatin-D induces apoptosis via activation of caspase-8 in acute T-cell leukemia cell line. |
CASP8 |
| 47 |
27929746 |
10.1080/15384101.2016.1261226 |
2017 |
Exogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells. |
CASP8 |
| 48 |
27998762 |
10.1016/j.canlet.2016.12.010 |
2017 |
Rocaglamide breaks TRAIL-resistance in human multiple myeloma and acute T-cell leukemia in vivo in a mouse xenogtraft model. |
CASP8 |
| 49 |
28154184 |
10.1074/jbc.M116.754184 |
2017 |
Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma. |
CASP8 |
| 50 |
28361856 |
|
2017 |
Aberrant promoter hypermethylation of selected apoptotic genes in childhood acute lymphoblastic leukemia among North Indian population. |
CASP8 |
| 51 |
24614587 |
10.1371/journal.pone.0091359 |
2016 |
KSHV RTA abolishes NFκB responsive gene expression during lytic reactivation by targeting vFLIP for degradation via the proteasome. |
CASP8 |
| 52 |
25248880 |
10.3109/10428194.2014.953149 |
2016 |
The potential evasion of immune surveillance in mucosa associated lymphoid tissue lymphoma by DcR2-mediated up-regulation of nuclear factor-κB. |
CASP8 |
| 53 |
25663566 |
10.1007/s12016-015-8466-y |
2016 |
Updated Understanding of Autoimmune Lymphoproliferative Syndrome (ALPS). |
CASP8 |
| 54 |
25697054 |
10.1016/j.steroids.2015.02.007 |
2016 |
24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8. |
CASP8 |
| 55 |
26142735 |
10.1007/s13277-015-3720-8 |
2016 |
Temozolomide sensitizes stem-like cells of glioma spheres to TRAIL-induced apoptosis via upregulation of casitas B-lineage lymphoma (c-Cbl) protein. |
CASP8 |
| 56 |
26398332 |
10.3892/mmr.2015.4323 |
2016 |
Mucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8-mediated death receptor apoptotic pathways. |
CASP8 |
| 57 |
26437781 |
10.1038/leu.2015.267 |
2016 |
A20 targets caspase-8 and FADD to protect HTLV-I-infected cells. |
CASP8 |
| 58 |
26479732 |
10.1080/09168451.2015.1095065 |
2016 |
Advanced glycation end-product (AGE) induces apoptosis in human retinal ARPE-19 cells via promoting mitochondrial dysfunction and activating the Fas-FasL signaling. |
CASP8 |
| 59 |
26549478 |
10.1016/j.cbi.2015.10.025 |
2016 |
Resveratrol induces cell death and inhibits human herpesvirus 8 replication in primary effusion lymphoma cells. |
CASP8 |
| 60 |
24621205 |
10.3109/00365513.2014.891257 |
2015 |
Association of BH3 interacting domain death agonist (BID) gene polymorphisms with proteinuria of immunoglobulin A nephropathy. |
CASP8 |
| 61 |
25060748 |
10.3892/mmr.2014.2379 |
2015 |
Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo. |
CASP8 |
| 62 |
25207815 |
10.1371/journal.pone.0106788 |
2015 |
Gene expression profiling identifies IRF4-associated molecular signatures in hematological malignancies. |
CASP8 |
| 63 |
25345447 |
10.1517/17460441.2015.974544 |
2015 |
Neuroblastoma models for insights into tumorigenesis and new therapies. |
CASP8 |
| 64 |
25446254 |
10.1016/j.cellsig.2014.11.014 |
2015 |
TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways. |
CASP8 |
| 65 |
25470234 |
10.4161/15548627.2014.981790 |
2015 |
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions. |
CASP8 |
| 66 |
25477070 |
10.1186/s13045-014-0088-y |
2015 |
c-FLIP is involved in tumor progression of peripheral T-cell lymphoma and targeted by histone deacetylase inhibitors. |
CASP8 |
| 67 |
25534662 |
10.1007/s00775-014-1221-7 |
2015 |
Phosphonomethyl iminodiacetic acid-conjugated cobalt oxide nanoparticles liberate Co(++) ion-induced stress associated activation of TNF-α/p38 MAPK/caspase 8-caspase 3 signaling in human leukemia cells. |
CASP8 |
| 68 |
25551567 |
10.4161/15548627.2014.984270 |
2015 |
Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. |
CASP8 |
| 69 |
25578476 |
10.1038/leu.2015.9 |
2015 |
BIN1 tumor suppressor regulates Fas/Fas ligand-mediated apoptosis through c-FLIP in cutaneous T-cell lymphoma. |
CASP8 |
| 70 |
25738497 |
10.1371/journal.pone.0117994 |
2015 |
Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis. |
CASP8 |
| 71 |
25850729 |
10.1016/j.leukres.2015.03.010 |
2015 |
LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. |
CASP8 |
| 72 |
26117011 |
10.7534/j.issn.1009-2137.2015.03.010 |
2015 |
[Salinomycin Enhances the Apoptosis of T-cell Acute Lymphoblastic Leukemia Cell Line Jurkat Cells Induced by Vincristine]. |
CASP8 |
| 73 |
26195820 |
10.1128/MCB.00692-15 |
2015 |
RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival. |
CASP8 |
| 74 |
23582793 |
10.1016/j.biopha.2013.02.002 |
2014 |
c-FLIP does not correlate with response to immunochemotherapy treatment and outcome of patients with nodal diffuse large B-cell lymphoma. |
CASP8 |
| 75 |
23828565 |
10.1038/cddis.2013.214 |
2014 |
Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways. |
CASP8 |
| 76 |
23844036 |
10.1371/journal.pone.0067577 |
2014 |
Genetic polymorphisms of the CASP8 gene promoter may not be associated with colorectal cancer in Han Chinese from southwest China. |
CASP8 |
| 77 |
24352466 |
10.1128/JVI.03025-13 |
2014 |
Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis. |
CASP8 |
| 78 |
24370029 |
10.7534/j.issn.1009-2137.2013.06.017 |
2014 |
[Effect of midazolam on mantle cell lymphoma JeKo-1 cell line and its relevant mechanisms]. |
CASP8 |
| 79 |
22126780 |
|
2013 |
[Honokiol-induced apoptosis of human non-Hodgkin lymphoma Raji cells and its possible mechanism]. |
CASP8 |
| 80 |
22426257 |
10.1016/j.humimm.2012.02.018 |
2013 |
The role of BCL11B in regulating the proliferation of human naive T cells. |
CASP8 |
| 81 |
22860893 |
10.3109/10428194.2012.717079 |
2013 |
Interleukin-24 mediates apoptosis in human B-cells through early activation of cell cycle arrest followed by late induction of the mitochondrial apoptosis pathway. |
CASP8 |
| 82 |
23071110 |
10.1074/jbc.M112.419747 |
2013 |
Protease activity of procaspase-8 is essential for cell survival by inhibiting both apoptotic and nonapoptotic cell death dependent on receptor-interacting protein kinase 1 (RIP1) and RIP3. |
CASP8 |
| 83 |
23193206 |
10.2337/dc12-0194 |
2013 |
Caspase induction and BCL2 inhibition in human adipose tissue: a potential relationship with insulin signaling alteration. |
CASP8 |
| 84 |
23731686 |
10.1016/j.jss.2013.04.079 |
2013 |
Regulation of tumor necrosis factor-α-induced microvascular endothelial cell hyperpermeability by recombinant B-cell lymphoma-extra large. |
CASP8 |
| 85 |
23770605 |
10.1038/ng.2652 |
2013 |
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. |
CASP8 |
| 86 |
23804715 |
10.4049/jimmunol.1202514 |
2013 |
Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells. |
CASP8 |
| 87 |
21638304 |
10.1002/hon.996 |
2012 |
Cellular (FLICE) like inhibitory protein (cFLIP) expression in diffuse large B-cell lymphoma identifies a poor prognostic subset, but fails to predict the molecular subtype. |
CASP8 |
| 88 |
21737742 |
10.1210/me.2011-0046 |
2012 |
TSH receptor function is required for normal thyroid differentiation in zebrafish. |
CASP8 |
| 89 |
21952919 |
10.1002/ijc.26458 |
2012 |
Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas. |
CASP8 |
| 90 |
21954216 |
10.1002/pbc.23331 |
2012 |
Inhibition of caspase-8 activity caused by overexpression of BCL10 contributes to the pathogenesis of high-grade MALT lymphoma. |
CASP8 |
| 91 |
22010212 |
10.1158/1078-0432.CCR-11-0513 |
2012 |
Important role of caspase-8 for chemosensitivity of ALL cells. |
CASP8 |
| 92 |
22011910 |
10.1038/jid.2011.316 |
2012 |
Nonsteroidal anti-inflammatory drugs induce apoptosis in cutaneous T-cell lymphoma cells and enhance their sensitivity for TNF-related apoptosis-inducing ligand. |
CASP8 |
| 93 |
22086925 |
10.1074/jbc.M111.286526 |
2012 |
Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression. |
CASP8 |
| 94 |
22173242 |
10.1038/leu.2011.353 |
2012 |
RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis. |
CASP8 |
| 95 |
22190004 |
10.1038/cddis.2011.131 |
2012 |
The role of c-FLIP splice variants in urothelial tumours. |
CASP8 |
| 96 |
22205673 |
10.2527/jas.2011-4340 |
2012 |
9-cis Retinoic acid inhibits cumulus cell apoptosis during the maturation of bovine cumulus-oocyte-complexes. |
CASP8 |
| 97 |
22211869 |
10.3109/10428194.2011.654117 |
2012 |
Functional polymorphisms in FAS, FASL and CASP8 genes and risk of childhood acute lymphoblastic leukemia: a case-control study. |
CASP8 |
| 98 |
22221251 |
10.1111/j.1365-2184.2011.00801.x |
2012 |
A new development of triterpene acid-containing extracts from Viscum album L. displays synergistic induction of apoptosis in acute lymphoblastic leukaemia. |
CASP8 |
| 99 |
22343728 |
10.1182/blood-2011-07-367532 |
2012 |
Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis. |
CASP8 |
| 100 |
22393362 |
10.1371/journal.pone.0031366 |
2012 |
Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia. |
CASP8 |
Datasets
Models
