<table><tbody><tr><td><table cellpadding="2" cellspacing="0" width="600"><tbody><tr bgcolor="#cccccc" valign="top"><td colspan="2"><table width="600"><tbody><tr><td><strong class="acc" id="GSE197137"><a href="/geo/query/acc.cgi?acc=GSE197137" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">Series GSE197137</a></strong></td>

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<td align="right" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_gds)"><a href="/gds/?term=GSE197137[Accession]">Query DataSets for GSE197137</a></td>

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<tr valign="top"><td>Status</td>

<td>Public on Feb 23, 2022</td>

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<tr valign="top"><td nowrap="">Title</td>

<td style="text-align: justify">Expression alteration of plasma exosomal circular RNAs in OSA patients with acute myocardial infarction</td>

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<tr valign="top"><td nowrap="">Organism</td>

<td><a href="/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=9606" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_organismus)">Homo sapiens</a></td>

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<tr valign="top"><td nowrap="">Experiment type</td>

<td>Non-coding RNA profiling by array<br></td>

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<tr valign="top"><td nowrap="">Summary</td>

<td style="text-align: justify">This study demonstrated that there were a number of dysregulated circRNAs in exosomes from OSA with AMI patients, which might be effectively served as a promising diagnostic biomarker and therapeutic targets. Objectives: Circular RNAs (circRNAs) are recently identified as a class of non-coding RNAs that participate in the incidence of acute myocardial infarction(AMI)<br></td>

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<tr valign="top"><td nowrap="">Overall design</td>

<td style="text-align: justify">The plasma exosomal circRNAs profile of three healthy subjects, three OSA without AMI and three OSA with AMI were analyzed using high-throughput sequencing. Bioinformatic analyses were carried out to assess potential core circRNAs and functional analyses were conducted to study biological functions.<br></td>

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<tr valign="top"><td>Contributor(s)</td>

<td><a href="/pubmed/?term=Huang J[Author]">Huang J</a>, <a href="/pubmed/?term=Lian N[Author]">Lian N</a>, <a href="/pubmed/?term=Lin G[Author]">Lin G</a>, <a href="/pubmed/?term=Xie H[Author]">Xie H</a>, <a href="/pubmed/?term=Wang B[Author]">Wang B</a>, <a href="/pubmed/?term=Chen G[Author]">Chen G</a>, <a href="/pubmed/?term=Lin Q[Author]">Lin Q</a></td>

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<tr valign="top"><td>Citation missing</td>

<td class="message" id="pmidCell">Has this study been published? Please <a href="/geo/submitter">login</a> to update or <a href="mailto:geo@ncbi.nlm.nih.gov?subject=Citation for GSE197137 [not logged in]&amp;body=Thank you very much for helping to keep GEO citation links up-to-date. Please enter the PubMed ID (PMID) or full citation for GSE197137 below, and we will update the record accordingly within the next day or two. The PubMed ID or citation is:

">notify GEO</a>.</td>

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<tr valign="top"><td colspan="2"><span id="geo2r"><button class="button" id="geo2r_button"><span class="">Analyze with GEO2R</span></button></span> <span id="rnaseq_counts"></span></td></tr>

<tr bgcolor="#eeeeee" valign="top"><td>Submission date</td>

<td>Feb 21, 2022</td>

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<tr bgcolor="#eeeeee" valign="top"><td>Last update date</td>

<td>Feb 26, 2022</td>

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<tr bgcolor="#eeeeee" valign="top"><td>Contact name</td>

<td>Jie-feng Huang</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">E-mail(s)</td>

<td><a href="mailto:change@126.com">change@126.com</a><br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Organization name</td>

<td style="text-align: justify">First affiliated hospital of Fujian Medical University<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Street address</td>

<td style="text-align: justify">No 20, Chazhong road, Taijiang district<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">City</td>

<td style="text-align: justify">Fuzhou</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">ZIP/Postal code</td>

<td style="text-align: justify">350005</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Country</td>

<td style="text-align: justify">China</td>

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<tr valign="top"><td>Platforms (1)</td>

<td onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)"><table cellpadding="3" style="position:relative;top:-5px;left:-5px"><tbody><tr><td valign="top"><a href="/geo/query/acc.cgi?acc=GPL21825" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">GPL21825</a></td>

<td valign="top">074301 Arraystar Human CircRNA microarray V2</td>

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