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| Status |
Public on Feb 23, 2022 |
| Title |
Expression alteration of plasma exosomal circular RNAs in OSA patients with acute myocardial infarction |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
This study demonstrated that there were a number of dysregulated circRNAs in exosomes from OSA with AMI patients, which might be effectively served as a promising diagnostic biomarker and therapeutic targets. Objectives: Circular RNAs (circRNAs) are recently identified as a class of non-coding RNAs that participate in the incidence of acute myocardial infarction(AMI)
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| Overall design |
The plasma exosomal circRNAs profile of three healthy subjects, three OSA without AMI and three OSA with AMI were analyzed using high-throughput sequencing. Bioinformatic analyses were carried out to assess potential core circRNAs and functional analyses were conducted to study biological functions.
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| Contributor(s) |
Huang J, Lian N, Lin G, Xie H, Wang B, Chen G, Lin Q |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Feb 21, 2022 |
| Last update date |
Feb 26, 2022 |
| Contact name |
Jie-feng Huang |
| E-mail(s) |
change@126.com
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| Organization name |
First affiliated hospital of Fujian Medical University
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| Street address |
No 20, Chazhong road, Taijiang district
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| City |
Fuzhou |
| ZIP/Postal code |
350005 |
| Country |
China |
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| Platforms (1) |
| GPL21825 |
074301 Arraystar Human CircRNA microarray V2 |
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