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### About Dataset
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20292
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Zhang Y, James M, Middleton FA, Davis RL. Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. Am J Med Genet B Neuropsychiatr Genet 2005 Aug 5;137B(1):5-16. PMID: 15965975
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Zheng B, Liao Z, Locascio JJ, Lesniak KA et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med 2010 Oct 6;2(52):52ra73. PMID: 20926834
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Transcriptional analysis of whole substantia nigra in Parkinson's disease
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Expression profiling by array
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15 control
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11 disease
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(3 outlier controls omitted)
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Top 250 genes ranked by p value.
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value distribution