About Dataset

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20292

Zhang Y, James M, Middleton FA, Davis RL. Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. Am J Med Genet B Neuropsychiatr Genet 2005 Aug 5;137B(1):5-16. PMID: 15965975

Zheng B, Liao Z, Locascio JJ, Lesniak KA et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med 2010 Oct 6;2(52):52ra73. PMID: 20926834

Transcriptional analysis of whole substantia nigra in Parkinson's disease
Expression profiling by array

15 control
11 disease
(3 outlier controls omitted)

Top 250 genes ranked by p value.

value distribution