You should not use Zofran if you are also using apomorphine (Apokyn).
You should not use Zofran if you are allergic to ondansetron or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi).
Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
Serious side effects include blurred vision or temporary vision loss (lasting from only a few minutes to several hours), slow heart rate, trouble breathing, anxiety, agitation, shivering, feeling like you might pass out, and urinating less than usual or not at all. Stop taking Zofran and call your doctor at once if you have any of these side effects. Ondansetron may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Before taking this medicine
You should not use Zofran if:
you are also using apomorphine (Apokyn); or
you are allergic to ondansetron or similar medicines (dolasetron, granisetron, palonosetron).
To make sure Zofran is safe for you, tell your doctor if you have:
liver disease;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
congestive heart failure, slow heartbeats;
a personal or family history of long QT syndrome; or
a blockage in your digestive tract (stomach or intestines).
Zofran is not expected to harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Ondansetron is not approved for use by anyone younger than 4 years old.
Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
