Usual Adult Dose for Hypertension:
HYPERTENSION:Hydrochlorothiazide 12.5 to 25 mg-Losartan 50 to 100 mg orally once a dayMaximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a dayComments:-A patient whose blood pressure is not adequately controlled with hydrochlorothiazide or losartan monotherapy may be switched to hydrochlorothiazide 12.5 mg-losartan 50 mg orally once a day.-May increase dose if blood pressure remains uncontrolled after about 3 weeks.Use: Treatment of hypertension.  This drug is not indicated for initial therapy except when hypertension is severe enough that the benefit of achieving prompt blood pressure control exceeds the risk of initiating combination therapy.SEVERE HYPERTENSION:Initial treatment: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled after 2 to 4 weeks, may initiate maximum dose.Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a dayHYPERTENSION WITH LEFT VENTRICULAR HYPERTROPHY:Initial therapy: Losartan monotherapy; if blood pressure remains uncontrolled, may initiate this drug.Add-on therapy: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled, initiate hydrochlorothiazide 12.5 mg-losartan 100 mg orally once a day, followed by hydrochlorothiazide 25 mg-losartan 100 mg orally once a day, if needed.Use: To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients.
 Detailed Hydrochlorothiazide/losartan dosage information
