Usual Adult Dose for Diabetes Type 2:
Subcutaneous Administration:
Initial dose: 0.25 mg subcutaneously once a week for 4 weeks, then 0.5 mg subcutaneously once a week
-If additional glycemic control is needed after at least 4 weeks receiving 0.5 mg dose subcutaneously once a week, may increase to 1 mg subcutaneously once a week
Maintenance dose: 0.5 to 1 mg subcutaneously once a week
Maximum dose: 1 mg/week
Usual Adult Dose for Cardiovascular Risk Reduction:
Subcutaneous Administration:
Initial dose: 0.25 mg subcutaneously once a week for 4 weeks, then 0.5 mg subcutaneously once a week
-If additional glycemic control is needed after at least 4 weeks receiving 0.5 mg dose subcutaneously once a week, may increase to 1 mg subcutaneously once a week
Maintenance dose: 0.5 to 1 mg subcutaneously once a week
Maximum dose: 1 mg/week
Comments:
Switching between Subcutaneous Administration and Oral Tablets:
-Patients receiving 14 mg orally once a day can be transitioned to 0.5 mg subcutaneously once a week; subcutaneous administration should start after last oral dose
-Patients receiving 0.5 mg subcutaneously once a week can be transitioned to 7 or 14 mg orally once a day; oral therapy should start up to 7 days after last subcutaneous injection
-No equivalent oral dose is recommended to replace a subcutaneous dose of 1 mg weekly
-Doses of 0.25 mg subcutaneously once a week and 3 mg orally once a day are intended for treatment initiation and are not effective doses for glycemic control.
-This drug has not been studied in patients with a history of pancreatitis; other antidiabetic therapies should be considered in these patients.
Uses:
-As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
-To reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) in adults with type 2 diabetes mellitus and established cardiovascular disease
 Detailed Ozempic dosage information
What happens if I miss a dose?
Ozempic: Use the medicine as soon as you can, but skip the missed dose if you are more than 5 days late for the dose. Do not use two doses within 5 days of each other.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
