Prolia is injected under the skin of your stomach, upper thigh, or upper arm. A healthcare provider will give you this injection.
Prolia is usually given once every 6 months.
Your doctor may have you take extra calcium and vitamin D while you are being treated with Prolia. Take only the amount of calcium and vitamin D that your doctor has prescribed.
If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Prolia.
Pay special attention to your dental hygiene. Brush and floss your teeth regularly while using this medication. You may need to have a dental exam before you begin treatment with Prolia. Follow your doctor's instructions.
Your risk of bone fractures can increase when you stop using Prolia. Do not stop using this medicine without first talking to your doctor.
If you keep this medicine at home, store it in the original container in a refrigerator. Protect from light and do not freeze.
You may take Prolia syringe out of the refrigerator and allow it to reach room temperature before the injection is given. Do not heat the medicine before using.
Do not shake the the prefilled syringe or you may ruin the medicine. Do not use the medicine if it looks cloudy or has particles in it. Call your pharmacist for a new prescription.
Each prefilled syringe of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.
After you have taken Prolia out of the refrigerator, you may keep it at room temperature for up to 14 days. Store in the original container away from heat and light.
Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Do not share this medicine with another person, even if they have the same symptoms you have.
 Detailed Prolia dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose or miss an appointment for your Prolia injection. You should receive your missed injection as soon as possible.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
