Get emergency medical help if you have signs of an allergic reaction to Skyrizi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
You may get infections more easily. Call your doctor right away if you have signs of infection such as:
fever, chills, sweating, body aches;
shortness of breath, cough, bloody mucus;
mouth sores, red or swollen gums;
stomach pain, diarrhea;
increased urination, burning when you urinate;
pale skin, easy bruising, unusual bleeding;
a fungal skin infection - skin sores different from psoriasis, rash or redness, blisters, itching, burning, cracking or peeling, changes in skin color; or
signs of tuberculosis: fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired.
If you develop an infection, you may need to postpone your next injection until the infection clears up.
Common Skyrizi side effects may include:
headache;
tiredness;
cold symptoms such as stuffy nose, sneezing, sore throat;
fungal skin infections; or
pain, redness, itching, bruising, swelling, warmth, bleeding, burning, or other skin irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Skyrizi side effects (more detail)
