INSERT INTO `drugs` VALUES (445,'kadcyla','Usual Adult Dose for Breast Cancer:\n3.6 mg/kg IV every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity\nMaximum dose: 3.6 mg/kg IV every 3 weeks\nComments:\n-Administer the first infusion over 90 minutes. Subsequent infusions may be administered over 30 minutes as tolerated.\n-Observe patients during and for at least 90 minutes following the initial dose for fever, chills, or other infusion-related reactions.\n-Patients should have a HER2 positive tumor status confirmed prior to starting therapy.\n-Do not substitute trastuzumab emtansine for or with trastuzumab.\n-If a planned dose is delayed or missed, it should be administered as soon as possible; do not wait until the next planned cycle.\nUse: As a single agent, for HER2-positive, metastatic breast cancer in patients who previously received trastuzumab and a taxane, separately or in combination; patients should have either:\n-Received prior therapy for metastatic disease\nOR\n-Developed disease recurrence during or within 6 months of completing adjuvant therapy\n Detailed Kadcyla dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Kadcyla injection.\nWhat happens if I overdose?\nSince this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may interact with ado-trastuzumab emtansine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Kadcyla drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kadcyla: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome side effects may occur during the injection. Tell your caregiver right away if you feel cold, light-headed, feverish or sweaty, or have chest tightness, rapid heartbeats, or trouble breathing.\nCall your doctor at once if you have:\neasy bruising, unusual bleeding, purple or red spots under your skin;\ncoughing up blood or vomit that looks like coffee grounds;\nbloody or tarry stools;\nchest pain, wheezing, dry cough, feeling short of breath;\nunusual tiredness, feeling light-headed;\npale skin, cold hands and feet;\nnumbness, tingling, or burning pain in your hands or feet;\nsudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems;\nliver problems - loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes); or\nsigns of tumor cell breakdown - confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon Kadcyla side effects may include:\neasy bruising or bleeding (especially nosebleeds);\nnausea, constipation;\njoint or muscle pain;\nheadache; or\nfeeling tired.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kadcyla side effects (more detail)\n','Kadcyla (ado-trastuzumab emtansine) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.\nKadcyla is used to treat HER2-positive breast cancer.\nKadcyla is used both for early breast cancer and for breast cancer that has spread to other parts of the body (metastatic).\nKadcyla is usually given after other cancer medications have been tried without success.\nKadcyla should not be used in place of Herceptin (trastuzumab).\n','Do not use Kadcyla if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.\nYou may need to have a negative pregnancy test before starting this treatment.\nKadcyla can harm your liver. Call your doctor at once if you have upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).\nBefore you receive each Kadcyla injection, your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).\nBefore taking this medicine\nYou should not use Kadcyla if you are allergic to ado-trastuzumab emtansine.\nDo not use Kadcyla if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose.\nTell your doctor if you become pregnant during treatment.\nTo make sure Kadcyla is safe for you, tell your doctor if you have ever had:\nheart problems;\nliver disease (especially hepatitis B or C);\nbleeding or blood clotting disorder such as hemophilia; or\nasthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder.\nYou should not breast-feed while using this medicine.\nHow is Kadcyla given?\nKadcyla is given as an infusion into a vein. A healthcare provider will give you this injection.\nThis medicine must be given slowly, and the infusion can take 30 to 90 minutes to complete.\nTell your caregivers if you feel any burning, pain, or swelling around the IV needle when Kadcyla is injected.\nKadcyla is usually given once every 3 weeks. Your doctor will determine how long to treat you.\nYou may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.\n','Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.\nAdo-trastuzumab emtansine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient\'s body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.\n'),(446,'kadian','Usual Adult Dose for Pain:\nExtended-release capsules:\nDifferent extended-release products are not bioequivalent. Conversion from one extended-release product to the same total daily dose of another extended-release product may lead to either excessive sedation at peak or inadequate analgesia at trough. Individual product information should be consulted before prescribing and the dosage should be adjusted to the individual patient.\nOpioid naive:\nInitial dose: 30 mg orally every 24 hours\nOpioid tolerant:\nAppropriate dose should be taken 1 to 2 times daily.\n Detailed Kadian dosage information\nWhat happens if I miss a dose?\nKadian is usually taken once per day (every 24 hours) or twice daily (every 12 hours). Since this medicine is used for pain, you are not likely to miss a dose. If you do miss a dose, take a dose as soon as you remember. Then take your next dose as follows:\nIf you take Kadian 1 time per day: Take your next dose 24 hours after taking the missed dose.\nIf you take Kadian 2 times per day: Take your next dose 12 hours after taking the missed dose.\nDo not take two doses at one time. Do not take more than your prescribed dose in a 24-hour period.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or person using opioid medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.\nYour doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don\'t wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.\nAnyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.\n','Many other drugs can be dangerous when used with opioid medicine. Tell your doctor if you also use:\nother opioid medicines;\na benzodiazepine sedative like Valium, Klonopin, or Xanax;\nsleep medicine, muscle relaxers, or other drugs that make you drowsy; or\ndrugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson\'s disease.\nThis list is not complete. Many drugs may interact with morphine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Kadian drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kadian: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nOpioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.\nCall your doctor at once if you have:\nslow heart rate, sighing, weak or shallow breathing, breathing that stops;\nchest pain, fast or pounding heartbeats;\nextreme drowsiness, feeling like you might pass out;\nserotonin syndrome - agitation, hallucinations, fever, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, diarrhea; or\nlow cortisol levels - nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.\nSerious breathing problems may be more likely in older adults and people who are debilitated or have wasting syndrome or chronic breathing disorders.\nCommon Kadian side effects may include:\ndrowsiness, dizziness, tiredness;\nconstipation, stomach pain, nausea, vomiting;\nsweating; or\nfeelings of extreme happiness or sadness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kadian side effects (more detail)\n','Kadian (morphine) is an opioid medication. An opioid is sometimes called a narcotic.\nKadian extended-release capsules are used to treat moderate to severe pain.\nKadian extended-release capsules are used for around-the-clock treatment of pain when other pain treatments, such as non-opioid pain medicines or immediate-release opioid medicines, do not treat your pain well enough or you cannot tolerate them.\nKadian is not for use on an as-needed basis for pain.\n','You should not take Kadian if you have severe asthma or breathing problems, a blockage in your stomach or intestines, or a bowel obstruction called paralytic ileus.\nMorphine can slow or stop your breathing, and may be habit-forming MISUSE OF KADIAN CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, , especially in a child or other person using the medicine without a prescription. Keep the medication in a place where others cannot get to it.\nTaking Kadian during pregnancy may cause life-threatening withdrawal symptoms in the newborn.\nFatal side effects can occur if you use Kadian with alcohol, or with other drugs that cause drowsiness or slow your breathing.\nBefore taking this medicine\nYou should not take Kadian if you have ever had an allergic reaction to morphine or other narcotic medicines, or if you have:\nsevere asthma or breathing problems;\na stomach or bowel obstruction (including paralytic ileus); or\nif you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.\nTo make sure Kadian is safe for you, tell your doctor if you have ever had:\nbreathing problems, sleep apnea (breathing stops during sleep);\na head injury, brain tumor, or seizures;\na drug or alcohol addiction, or mental illness;\nurination problems;\nliver or kidney disease; or\nproblems with your gallbladder, pancreas, or thyroid.\nIf you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.\nAsk a doctor before using opioid medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.\nHow should I use Kadian?\nTake Kadian exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Never use Kadian in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine.\nNever share opioid medicine with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.\nStop taking all other around-the-clock narcotic pain medications when you start taking Kadian.\nSwallow the capsule whole to avoid exposure to a potentially fatal overdose. Crushing, chewing, or dissolving the pellets will result in uncontrolled delivery of morphine and can lead to overdose or death\nYou may have withdrawal symptoms if you stop using Kadian suddenly. Ask your doctor before stopping the medicine.\nNever crush or break a Kadian capsule to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death with the misuse of morphine and similar prescription drugs.\nStore at room temperature, away from heat, moisture, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.\nDo not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.\n','Do not drink alcohol.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\n'),(447,'kalbitor','Usual Adult Dose for Hereditary Angioedema:\n30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.\nUsual Pediatric Dose for Hereditary Angioedema:\n12 years and older: 30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.\n Detailed Kalbitor dosage information\nWhat happens if I miss a dose?\nBecause you will receive Kalbitor in a medical setting, you are not likely to miss a dose.\nWhat happens if I overdose?\nSince this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur and would be treated quickly.\n','Other drugs may interact with ecallantide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n','Tell your caregivers right away if you have any of these signs of an allergic reaction to Kalbitor within 1 hour after receiving your injection:\nchest pain or tightness, fast or weak heartbeat;\nwheezing, cough, throat irritation, trouble breathing;\nhoarse voice, tight feeling in your throat, trouble swallowing;\nswelling of your lips, tongue, or throat;\nswelling or redness in your face;\nitching, rash, or hives;\nflushing (warmth, redness, or tingly feeling);\nsneezing, runny or stuffy nose; or\ndizziness, feeling like you might pass out.\nAn allergic reaction to ecallantide can cause symptoms that are similar to the signs of hereditary angioedema. Your caregivers will watch you closely and will quickly treat an allergic reaction to ecallantide.\nCommon Kalbitor side effects may include:\nheadache;\nnausea, diarrhea;\nfever;\nstuffy nose, sore throat; or\nskin reactions where the medicine was injected (redness, rash, itching, bruising, swelling).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kalbitor side effects (more detail)\n','Kalbitor (ecallantide) is used to treat attacks of hereditary angioedema (an immune system disorder). This medicine is for use in adults and children at least 12 years old.\nKalbitor is not a cure for hereditary angioedema.\nKalbitor may also be used for other purposes not listed in this medication guide.\n','You should not be treated with Kalbitor if you are allergic to ecallantide. Ecallantide can cause a serious allergic reaction within 1 hour after receiving an injection. Symptoms include wheezing, cough, trouble breathing or swallowing, itching, hives, dizziness, fainting, or swelling in your face or throat Tell your doctor if you have a history of any type of allergy.\nIn an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.\nBefore receiving this medicine\nYou should not be treated with Kalbitor if you are allergic to ecallantide.\nIf possible before you receive Kalbitor, tell your doctor if you have a history of any type of allergy.\nIt is not known whether Kalbitor will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether ecallantide passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nIn an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.\nHow is Kalbitor given?\nKalbitor is injected under the skin. A healthcare provider will give you this injection.\nYou will be watched closely after receiving your injection, to make sure you do not have an allergic reaction to the medication.\nKalbitor is usually given in 3 separate injections. If you still have symptoms of the angioedema attack, more injections may be given within 24 hours.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(448,'kaletra','Take Kaletra exactly as prescribed by your doctor. Follow all directions on your prescription label, especially when giving the medicine to a child. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nIf a child is taking this medication, tell your doctor if the child has any changes in weight. Doses are based on weight in children.\nDo not crush, chew, or break a tablet. Swallow the tablet whole.\nKaletra tablets can be taken with or without food.\nKaletra liquid should be taken with food. Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.\nWhile using this medicine, you may need frequent blood tests at your doctor\'s office.\nHIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor\'s advice. Every person with HIV or AIDS should remain under the care of a doctor.\nStore the liquid medicine in the refrigerator or at room temperature. If you store the liquid at room temperature you must use it within 60 days.\nStore the tablets at room temperature, away from heat and moisture. Keep the pills in their original container with the cap tightly closed.\n Detailed Kaletra dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Kaletra oral liquid could be fatal to a child.\n','Many drugs can interact with Kaletra. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:\nantibiotic or antifungal medicine;\nantiviral medicines to treat hepatitis C or HIV;\ncancer medicine;\nerectile dysfunction medicine;\nheart or blood pressure medicine;\nmedicine to prevent blood clots;\nmedicine to prevent organ transplant rejection;\nmedicine to treat pulmonary arterial hypertension;\nmedicine to treat severe depression or schizophrenia;\nnarcotic medicine;\nseizure medicine;\n\"statin\" cholesterol-lowering medicine; or\nsteroid medicine.\nThis list is not complete and many other drugs can interact with Kaletra. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.\n Kaletra drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kaletra: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nsigns of a kidney stone - pain in your side or lower back, blood in your urine, painful or difficult urination;\nhigh blood sugar - increased thirst, increased urination, fruity breath odor, weight loss; or\nsigns of liver or pancreas problems - loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nKaletra affects your immune system, which may cause certain side effects (even weeks or months after you\'ve taken this medicine). Tell your doctor if you have:\nsigns of a new infection - fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;\ntrouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or\nswelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.\nliquid\nKaletra can cause changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).\nCommon Kaletra side effects may include:\nnausea, vomiting, diarrhea; or\nhigh cholesterol or triglycerides.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kaletra side effects (more detail)\n','Kaletra contains a combination of lopinavir and ritonavir. Lopinavir and ritonavir are antiviral medications that prevent the human immunodeficiency virus (HIV) from multiplying in your body.\nKaletra is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS).\nKaletra is not a cure for HIV or AIDS.\n','Kaletra can cause a serious heart problem, especially if you use certain other medicines at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using.\nCall your doctor at once if you have a headache with chest pain, fast or pounding heartbeats, and severe dizziness.\nBefore taking this medicine\nYou should not use Kaletra if you have ever had a severe allergic reaction to lopinavir or ritonavir.\nSome medicines can cause unwanted or dangerous effects when used with Kaletra. Your doctor may need to change your treatment plan if you use any of the following drugs:\nalfuzosin;\napalutamide;\ncisapride;\ncolchicine;\ndronedarone;\nelbasvir/grazoprevir;\nlomitapide;\nlurasidone, pimozide;\nranolazine;\nrifampin;\nlovastatin, simvastatin;\ntriazolam, or oral midazolam;\nsildenafil (Revatio for pulmonary arterial hypertension);\nSt. John\'s wort; or\nan ergot medicine (ergotamine, dihydroergotamine, methylergonovine).\nTo make sure Kaletra is safe for you, tell your doctor if you have ever had:\nliver disease (especially hepatitis B or C);\nheart disease, heart rhythm disorder, or a family history of long QT syndrome;\npancreas problems;\ndiabetes;\nlow levels of potassium in your blood; or\na bleeding disorder such as hemophilia.\nIt is not known whether Kaletra will harm an unborn baby. But HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.\nIf you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Kaletra on the baby.\nKaletra can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using Kaletra, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.\nWomen with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.\nKaletra is not approved for use by anyone younger than 14 days old. Premature infants should not receive the medication until it has been 14 days after their original due date.\n','If you take Kaletra liquid and you also take didanosine (Videx), take the didanosine at least 1 hour before or 2 hours after you take the liquid medicine.\nKaletra liquid contains alcohol. Avoid drinking alcohol while using this medicine.\nTaking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.\n'),(449,'kaopectate','Use exactly as directed on the label, or as prescribed by your doctor.\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nYou must chew the chewable tablet before you swallow it.\nDrink plenty of liquids while you are taking Kaopectate.\nDo not take more than 8 doses in one day (24 hours).\nCall your doctor if you still have diarrhea after 2 days of using  Kaopectate.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Kaopectate.\nStore at room temperature away from moisture and heat. Do not freeze.\n Detailed Kaopectate dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nSince  Kaopectate is used when needed, you may not be on a dosing schedule. Skip any missed dose if it\'s almost time for your next dose. Do not use two doses at one time.\nDo not take more than 8 doses per day.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include weakness, depression, anxiety, feeling irritable, problems with balance or coordination, confusion, tremors, or jerky muscle movements.\n','Ask a doctor or pharmacist before using Kaopectate with any other medications, especially:\narthritis medicine;\ngout medicine;\ninsulin or oral diabetes medications; or\na blood thinner--warfarin, Coumadin, Jantoven.\nThis list is not complete. Other drugs may affect Kaopectate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Kaopectate drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nStop taking  Kaopectate and call your doctor at once if you have:\nchanges in behavior with nausea and vomiting;\nhearing loss or ringing in your ears;\ndiarrhea lasting longer than 2 days; or\nworsened stomach symptoms.\nKaopectate can cause you to have a black or darkened tongue. This is a harmless side effect.\nCommon side effects include:\nconstipation; or\ndark colored stools.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kaopectate side effects (more detail)\n','Kaopectate is used to treat diarrhea, nausea, heartburn, indigestion, gas, or upset stomach.\nKaopectate may also be used for purposes not listed in this medication guide.\n','You should not use  Kaopectate if you have bleeding problems, a stomach ulcer, blood in your stools, or if you are allergic to aspirin or other salicylates.\nDo not give this medicine to a child or teenager with a fever, flu symptoms, or chickenpox.\nBefore taking this medicine\nYou should not use Kaopectate if you are allergic to it, or if you have:\nblack or bloody stools;\na stomach ulcer;\nbleeding problems; or\nif you are allergic to salicylates such as aspirin, Doan\'s Extra Strength, Salflex, Tricosal, and others.\nDo not give this medicine to a child or teenager with a fever, flu symptoms, or chickenpox. Salicylates can cause Reye\'s syndrome, a serious and sometimes fatal condition in children.\nAsk a doctor or pharmacist if this medicine is safe to use if you have:\nmucus in your stools; or\nif you currently have a fever.\nAsk a doctor before using this medicine if you are pregnant or breastfeeding.\nDo not give this medicine to a child younger than 12 years old without medical advice.\n','Ask a doctor or pharmacist before taking other antacids or diarrhea medicine, or taking medicine that may contain a salicylate (such as aspirin, salsalate, magnesium salicylate, choline salicylate, diflunisal, Ecotrin, Tricosal, Trilisate, and others).\n'),(450,'kapvay','Take Kapvay exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nKapvay is usually taken in the morning and at bedtime. If you take different doses of this medicine at each dosing time, it may be best to take the larger dose at bedtime.\nKapvay may be taken with or without food.\nDo not use two forms of clonidine at the same time. The Catapres brand of clonidine is used to treat hypertension (high blood pressure). The Kapvay brand is used to treat attention deficit hyperactivity disorder (ADHD).\nDo not crush, chew, or break an extended-release Kapvay tablet. Swallow it whole. Tell your doctor if you have trouble swallowing the tablet.\nIf you need surgery, tell the surgeon ahead of time that you are using Kapvay. You may need to stop using the medicine for a short time.\nDo not stop using Kapvay suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.\nCall your doctor if you are sick with vomiting. Prolonged illness can make it harder for your body to absorb clonidine, which may lead to withdrawal symptoms. This is especially important for a child taking Kapvay.\nIf you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.\nStore at room temperature away from moisture, heat, and light.\n Detailed Kapvay dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include dangerously high blood pressure (severe headache, pounding in your neck or ears, nosebleed, anxiety, chest pain, shortness of breath) followed by low blood pressure (feeling like you might pass out). Other overdose symptoms may include feeling cold, extreme weakness or drowsiness, weak or shallow breathing, pinpoint pupils, fainting, or seizure (convulsions).\n','Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking Kapvay with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.\nTell your doctor about all your current medicines and any you start or stop using, especially:\nother heart or blood pressure medications;\nan antidepressant; or\nany other medicine that contains clonidine.\nThis list is not complete. Other drugs may interact with clonidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Kapvay drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kapvay: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere chest pain, shortness of breath, irregular heartbeats;\na very slow heart rate;\nsevere headache, pounding in your neck or ears, blurred vision;\nnosebleeds;\nanxiety, confusion; or\na light-headed feeling, like you might pass out.\nSerious side effects may be more likely in older adults.\nCommon Kapvay side effects may include:\ndrowsiness, dizziness, headache;\nfeeling tired or irritable;\ndry mouth, loss of appetite;\nconstipation;\ndry eyes, contact lens discomfort; or\nsleep problems (insomnia), nightmares.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kapvay side effects (more detail)\n','Kapvay (clonidine) is a prescription medicine supplied as an extended-release tablet and is used to treat attention deficit hyperactivity disorder (ADHD). Your doctor may prescribe Kapvay alone or together with certain other ADHD medicines. Clonidine is not a central nervous system (CNS) stimulant.\nKapvay may also be used for purposes not listed in this medication guide.\n','Before you take Kapvay, tell your doctor if you have heart disease or severe coronary artery disease, a heart rhythm disorder, slow heartbeats, low blood pressure, a history of heart attack or stroke, kidney disease, or if you have ever had an allergic reaction to a clonidine transdermal skin patch (Catapres TTS).\nBefore taking this medicine\nYou should not take Kapvay if you are allergic to clonidine.\nTo make sure Kapvay is safe for you, tell your doctor if you have:\nheart disease or severe coronary artery disease;\nheart rhythm disorder, slow heartbeats;\nlow blood pressure, or a history of fainting spells;\na history of heart attack or stroke;\npheochromocytoma (tumor of the adrenal gland);\nkidney disease; or\nif you have ever had an allergic reaction to a clonidine transdermal skin patch (Catapres TTS).\nOlder adults may be more sensitive to the effects of this medicine.\nIt is not known whether Kapvay will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while taking Kapvay.\nClonidine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nDo not give Kapvay to a child younger than 6 years old.\n','Avoid drinking alcohol. It may increase certain side effects of Kapvay.\nKapvay may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.\n'),(451,'kariva','Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nYou will take your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms or a spermicide, when you first start using this medicine. Follow your doctor\'s instructions.\nTake one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You may get pregnant if you do not take one pill daily. Get your prescription refilled before you run out of pills completely.\nSome birth control packs contain seven \"reminder\" pills to keep you on your regular cycle. Your period will usually begin while you are using these reminder pills.\nYou may have breakthrough bleeding, especially during the first 3 months. Tell your doctor if this bleeding continues or is very heavy.\nUse a back-up birth control if you are sick with severe vomiting or diarrhea.\nIf you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using birth control pills.\nWhile taking birth control pills, you will need to visit your doctor regularly.\nStore at room temperature away from moisture and heat.\n Detailed Kariva dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nFollow the patient instructions provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Missing a pill increases your risk of becoming pregnant.\nIf you miss one active pill, take two pills on the day you remember. Then take one pill per day for the rest of the pack.\nIf you miss two active pills in a row in Week 1 or 2, take two pills per day for two days in a row. Then take one pill per day for the rest of the pack. Use back-up birth control for at least 7 days following the missed pills.\nIf you miss two active pills in a row in Week 3, throw out the rest of the pack and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.\nIf you miss three active pills in a row in Week 1, 2, or 3, throw out the rest of the pack and start a new pack on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.\nIf you miss two or more pills, you may not have a period during the month. If you miss a period for two months in a row, call your doctor because you might be pregnant.\nIf you miss a reminder pill, throw it away and keep taking one reminder pill per day until the pack is empty.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, and vaginal bleeding.\n','Other drugs may interact with birth control pills, including prescription and over-the-counter medicines, vitamins, and herbal products. Some drugs can make birth control pills less effective, which may result in pregnancy. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Kariva drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using birth control pills and call your doctor at once if you have:\nsigns of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;\nsigns of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;\nheart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;\nliver problems--loss of appetite, upper stomach pain, tiredness, fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nincreased blood pressure--severe headache, blurred vision, pounding in your neck or ears;\nswelling in your hands, ankles, or feet;\nchanges in the pattern or severity of migraine headaches;\na breast lump; or\nsymptoms of depression--sleep problems, weakness, tired feeling, mood changes.\nCommon side effects may include:\nnausea, vomiting (especially when you first start taking  Kariva);\nbreast tenderness;\nbreakthrough bleeding;\nacne, darkening of facial skin;\nweight gain; or\nproblems with contact lenses.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kariva side effects (more detail)\n','Kariva is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary).  Kariva also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.\nKariva is used to prevent pregnancy. There are many brands of this medicine available. Not all brands are listed on this leaflet.\nKariva may also be used for purposes not listed in this medication guide.\n','Do not use birth control pills if you are pregnant or if you have recently had a baby.\nYou should not use birth control pills if you have: uncontrolled high blood pressure, heart disease, coronary artery disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, jaundice caused by pregnancy or birth control pills, or cancer of the breast, uterus/cervix, or vagina.\nTaking birth control pills can increase your risk of blood clots, stroke, or heart attack.\nSmoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take birth control pills if you smoke and are over 35 years old.\nBefore taking this medicine\nTaking birth control pills can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking birth control pills. Your risk is also high when you restart birth control pills after not taking them for 4 weeks or longer.\nSmoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not take combination birth control pills if you smoke and are over 35 years old.\nDo not use if you are pregnant. Stop using  Kariva and tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking birth control pills.\nYou should not take birth control pills if you have:\nuntreated or uncontrolled high blood pressure;\nheart disease (chest pain, coronary artery disease, history of heart attack, stroke, or blood clot);\nan increased risk of having blood clots due to a heart problem or a hereditary blood disorder;\ncirculation problems (especially if caused by diabetes);\na history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;\nunusual vaginal bleeding that has not been checked by a doctor;\nliver disease or liver cancer;\nsevere migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;\na history of jaundice caused by pregnancy or birth control pills;\nif you smoke and are over 35 years old; or\nif you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir (Technivie).\nTo make sure birth control pills are safe for you, tell your doctor if you have ever had:\nheart disease, high blood pressure, or if you are prone to having blood clots;\nvaricose veins;\nhigh cholesterol or triglycerides, or if you are overweight;\ndepression;\nmigraine headaches;\ndiabetes, gallbladder disease;\nliver or kidney disease;\nirregular menstrual cycles; or\nfibrocystic breast disease, lumps, nodules, or an abnormal mammogram.\nThe hormones in birth control pills can pass into breast milk and may harm a nursing baby. This medicine may also slow breast milk production. Do not use if you are breast feeding a baby.\n','Do not smoke while taking birth control pills, especially if you are older than 35 years of age.\nBirth control pills will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.\n'),(452,'kayexalate','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nKayexalate can be given as a liquid by mouth, through a stomach feeding tube, or as a rectal enema.\nDo not give  Kayexalate orally (by mouth) to a newborn baby. Do not use the medicine orally or rectally in a baby who has slow digestion caused by surgery or by using other medicines.\nTo give this medicine orally: Mix the Kayexalate powder with water, or with honey or jam to make it taste better. Avoid inhaling the oral powder while you are preparing a dose.\nDo not mix the powder with any juice or other liquid that contains potassium, such as orange juice.\nThe rectal enema form of this medicine is usually given by a healthcare professional. The enema will be inserted slowly while you are lying down. You may need to hold in the enema for up to several hours. The Kayexalate enema is usually followed with a second cleansing enema.\nYou will need frequent medical tests to help your doctor determine how long to treat you with Kayexalate.\nKeep using this medicine even if you feel fine. Hyperkalemia often has no symptoms that you will notice until your potassium levels are very low.\nStore at room temperature away from moisture and heat.\n Detailed Kayexalate dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Kayexalate can make it harder for your body to absorb medicines you take by mouth. Avoid taking other medicines within 3 hours before or 3 hours after you take this medicine.\nIf you have a condition that slows your digestion, avoid taking other medicines by mouth within 6 hours before or 6 hours after you take Kayexalate.\nTell your doctor about all your other medicines. Some may affect Kayexalate, especially:\ndigoxin, digitalis;\nlithium;\nthyroxine; or\ndrugs that weaken the immune system such as cancer medicine, steroids, and medicines to prevent organ transplant rejection.\nThis list is not complete. Other drugs may affect Kayexalate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Kayexalate drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using Kayexalate and call your doctor at once if you have:\nstomach pain, rectal pain;\nsevere constipation, severe stomach pain, bloating;\nfever, chills, vomiting;\nconfusion, thinking problems, feeling irritable;\nlow potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;\nlow calcium levels--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes); or\nsigns of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nCommon side effects may include:\nnausea, vomiting;\ndiarrhea, constipation; or\nloss of appetite.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kayexalate side effects (more detail)\n','Kayexalate binds itself to potassium in your digestive tract. This helps prevent your body from absorbing too much potassium.\nKayexalate is used to treat high levels of potassium in the blood, also called hyperkalemia.\nKayexalate works differently from other medicines because it passes into your intestines without being absorbed into your blood stream.\nKayexalate may also be used for purposes not listed in this medication guide.\n','You should not use  Kayexalate if you have low potassium levels or a bowel obstruction.\nDo not give this medicine orally (by mouth) to a newborn baby.\nAvoid taking other medicines by mouth within 3 hours before or 3 hours after you take Kayexalate (or 6 hours before/after if you have slow digestion).\nBefore taking this medicine\nYou should not use Kayexalate if you are allergic to it, or if you have:\nlow potassium levels (hypokalemia); or\na bowel obstruction.\nTell your doctor if you have ever had:\nheart disease or high blood pressure;\na weak immune system caused using certain medicine;\nsevere constipation or other bowel problems;\nkidney disease (or if you are on dialysis);\nan electrolyte imbalance (such as low levels of potassium, calcium, or magnesium in your blood);\nfluid retention;\nsevere burns;\na bowel disorder, or surgery on your intestines;\nif you are dehydrated; or\nif you are on a low-salt diet.\nBecause Kayexalate is not absorbed into the bloodstream, this medicine is not expected to be harmful during pregnancy or while nursing a baby. Tell your doctor if you are pregnant or breast-feeding.\n','Avoid using antacids or laxatives without your doctor\'s advice. Antacids or laxatives can make Kayexalate less effective, or cause serious side effects.\nDo not use potassium supplements, calcium supplements, or salt substitutes while you are taking Kayexalate, unless your doctor has told you to.\nAvoid eating or drinking anything that contains sorbitol (a fruit sugar often used as a sweetener in chewing gum, diet drinks, baked goods, or frozen desserts).\n'),(453,'kcentra','Usual Adult Dose for Reversal of Acquired Coagulation Factor Deficiency:\nINR 2 to less than 4: 25 units of Factor IX/kg body weight given intravenously\nINR 4 to 6: 35 units of Factor IX/kg body weight given intravenously\nINR greater than 6: 50 units of Factor IX/kg body weight given intravenously\nMaximum dose:\nINR 2 to less than 4: 2500 units of Factor IX\nINR 4 to 6: 3500 units of Factor IX\nINR greater than 6: 5000 units of Factor IX\nDuration of therapy: Single dose. Repeat dosing is not supported by clinical data and is not recommended.\nComments:\n-Administer Vitamin K concurrently to maintain Vitamin K dependent clotting factor levels once the effects of Kcentra concentrate have diminished.\n-Individualize dosing based on the patient\'s current predose International Normalized Ratio (INR) value, and body weight.\n-Dose is based on body weight up to but not exceeding 100 kg. Do not exceed stated maximum dose for patients weighing more than 100 kg.\n-Dosing is based on actual potency. The potency varies from vial to vial and is stated on the carton. Potency varies from 20-31 Factor IX units/mL. Nominal potency is 500 units per vial or approximately 25 units per mL after reconstitution.\n Detailed Kcentra dosage information\nWhat happens if I miss a dose?\nSince Kcentra is used when needed, it is usually given as a single dose.\nWhat happens if I overdose?\nSince this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.\n','Other drugs may interact with prothrombin complex, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Kcentra drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kcentra: hives, rash; nausea, vomiting, feeling light-headed; fast heartbeats; chest tightness, wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.\nTell your caregivers right away if you have:\na light-headed feeling, like you might pass out;\nchest pain or pressure, pain when you breathe, shortness of breath;\nflushing (sudden warmth, redness, or tingly feeling);\nlow red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet;\nsigns of a stroke - sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems;\nsigns of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or\nsigns of a blood clot deep in the body - swelling or pain in your arms, legs, or stomach.\nCommon Kcentra side effects may include:\nlow blood pressure;\nanemia;\nnausea, vomiting; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kcentra side effects (more detail)\n','Kcentra (prothrombin complex) is a blood coagulation factor replacement product.\nKcentra is used to quickly reverse the effects of a blood-thinning medicine (such as warfarin) during a major bleeding episode, or when there is a need for emergency surgery or invasive medical procedure.\nKcentra is for use in adults and dosing is based on body weight.\n','While using Kcentra, tell your caregivers right away if you have signs of a blood clot: sudden numbness or weakness, problems with vision or speech, chest pain, cough, wheezing, rapid breathing, swelling or pain in your arms, legs, or stomach.\nTell your doctor if you have ever had a heart attack, stroke, TIA or \"mini-stroke\", chest pain, severe circulation problems, or a blood clot (especially within the past 3 months).\nKcentra is for use in people who use blood thinners such as warfarin. After you are treated with this medicine, do not start using your blood thinner again until your doctor tells you to.\nBefore taking this medicine\nYou should not be treated with Kcentra if you have:\nlow levels of platelets in your blood after using heparin;\nexcessive blood-clotting caused by a condition called disseminated intravascular coagulation; or\na history of severe allergic reaction to prothrombin complex, Protein C or Protein S, Antithrombin III, heparin, human albumin, or Factors II, VII, IX, X.\nIf possible before you receive Kcentra, tell your caregivers if you have ever had:\na stroke, including TIA (transient ischemic attack) or \"mini-stroke\";\na heart attack;\ndisseminated intravascular coagulation;\nsevere circulation problems;\nchest pain (angina); or\nif you have had a blood-clot within the last 3 months.\nTell your doctor if you are pregnant or breastfeeding.\nKcentra is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.\nHow is Kcentra given?\nKcentra is given as an infusion into a vein. A healthcare provider will give you this injection.\nAfter you are treated with Kcentra, do not start using your blood thinner again until your doctor tells you to.\nIn case of emergency, wear or carry medical identification to let others know you use a blood thinner.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(454,'keflex','Take Keflex exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nDo not use Keflex to treat any condition that has not been checked by your doctor.\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Cephalexin will not treat a viral infection such as the flu or a common cold.\nDo not share Keflex with another person, even if they have the same symptoms you have.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine.\nStore the tablets and capsules at room temperature away from moisture, heat, and light.\n Detailed Keflex dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include nausea, vomiting, stomach pain, diarrhea, and blood in your urine.\n','Tell your doctor about all your other medicines, especially:\nmetformin; or\nprobenecid.\nThis list is not complete. Other drugs may interact with cephalexin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Keflex drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Keflex (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nCall your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);\nunusual tiredness, feeling light-headed or short of breath;\neasy bruising, unusual bleeding, purple or red spots under your skin;\na seizure;\npale skin, cold hands and feet;\nyellowed skin, dark colored urine;\nfever, weakness; or\npain in your side or lower back, painful urination.\nCommon Keflex side effects may include:\ndiarrhea;\nnausea, vomiting;\nindigestion, stomach pain; or\nvaginal itching or discharge.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Keflex side effects (more detail)\n','Keflex (cephalexin) is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body.\nKeflex is used to treat infections caused by bacteria, including upper respiratory infections, ear infections, skin infections, urinary tract infections and bone infections.\nKeflex is used to treat infections in adults and children who are at least 1 year old.\n','You should not use Keflex if you are allergic to cephalexin or to similar antibiotics, such as Ceftin, Cefzil, Omnicef, and others. Tell your doctor if you are allergic to any drugs, especially penicillins or other antibiotics.\nTell your doctor if you have kidney disease, liver disease, a stomach or intestinal disorder such as colitis, or diabetes.\nTake this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Keflex will not treat a viral infection such as the common cold or flu.\nBefore taking this medicine\nTo make sure Keflex is safe for you, tell your doctor if you have ever had\nan allergy to any drug (especially penicillin);\nliver or kidney disease; or\nintestinal problems, such as colitis.\nTell your doctor if you are pregnant or breast-feeding.\n','Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.\n'),(455,'kenalog','Use Kenalog exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.\nKenalog topical will not treat a bacterial, fungal, or viral skin infection.\nWash your hands before and after each application, unless you are using Kenalog to treat a hand condition.\nApply a small amount to the affected area and rub it gently into the skin.\nAvoid using Kenalog on your face, near your eyes or mouth, or on body areas where you have skin folds or thin skin.\nIf you are using the dental paste, apply the medication in a thin layer, just enough to cover the mouth ulcer. The paste may stick better if you dry the mouth ulcer before applying the medication.\nDo not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with Kenalog can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor\'s instructions. Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days. It is important to use Kenalog regularly to get the most benefit.\nStore at room temperature away from moisture and heat.\n Detailed Kenalog dosage information\nWhat happens if I miss a dose?\nUse the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222, especially if anyone has accidentally swallowed this medicine. An overdose of Kenalog applied to the skin is not expected to produce life-threatening symptoms.\n','It is not likely that other drugs you take orally or inject will have an effect on topically applied Kenalog. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\n Kenalog drug interactions (more detail)\n','Get emergency medical help if you have any of these signs of an allergic reaction to Kenalog: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using this medication and call your doctor at once if you have any of these signs that you may be absorbing triamcinolone through your skin or gums:\nblurred vision, or seeing halos around lights;\nuneven heartbeats;\nmood changes;\nsleep problems (insomnia);\nweight gain, puffiness in your face; or\nfeeling tired.\nLess serious Kenalog side effects may include:\nskin redness, burning, itching, or peeling;\nthinning of your skin; or\nblistering skin; or\nstretch marks.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kenalog side effects (more detail)\n','Kenalog contains triamcinolone, a potent corticosteroid. Triamcinolone reduces the actions of chemicals in the body that cause inflammation.\nKenalog topical is used to treat the inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis. The dental paste form of triamcinolone (Kenalog Orabase) is used to treat mouth ulcers.\nKenalog topical may also be used for purposes not listed in this medication guide.\n','Use Kenalog exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended.\nDo not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with Kenalog can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor\'s instructions.\nAvoid using Kenalog on your face, near your eyes, or on body areas where you have skin folds or thin skin.\nDo not use Kenalog on a child without a doctor\'s advice. Children are more sensitive to the effects of Kenalog.\nKenalog topical will not treat a bacterial, fungal, or viral skin infection.\nContact your doctor if your condition does not improve or if it gets worse after using this medication for several days.\nBefore using Kenalog\nDo not use Kenalog if you are allergic to triamcinolone.\nTo make sure you can safely use Kenalog, tell your doctor if you have any of these other conditions:\nany skin infection, especially tuberculosis infection of the skin;\nchicken pox or herpes infection (including cold sores);\ndiabetes; or\na stomach ulcer.\nIt is not known whether Kenalog will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether triamcinolone passes into breast milk or if it could harm a nursing baby. Do not use Kenalog without telling your doctor if you are breastfeeding a baby. Do not use this medication on a child without a doctor\'s advice. Children are more sensitive to the effects of Kenalog.\n','Avoid getting Kenalog in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use Kenalog on sunburned, windburned, irritated, or broken skin. Also avoid using Kenalog in open wounds.\nAvoid using skin products that can cause irritation, such as harsh soaps or skin cleansers, or skin products with alcohol, spices, astringents, or lime. Avoid using other medications on the areas you treat with Kenalog unless your doctor tells you to.\n'),(456,'kenalog-40','This section provides information on the proper use of a number of products that contain triamcinolone.  It may not be specific to Kenalog-40. Please read with care.\nA nurse or other trained health professional will give you this medicine. You may also be taught how to give your medicine at home. This medicine is given as a shot into one of your muscles, a joint, or a spot on your skin called a lesion.\n Detailed Kenalog-40 dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor or nurse immediately if any of the following side effects occur:\nMore common\nAggression\nagitation\nanxiety\nblurred vision\ndecrease in the amount of urine\ndizziness\nfast, slow, pounding, or irregular heartbeat or pulse\nheadache\nirritability\nmental depression\nmood changes\nnervousness\nnoisy, rattling breathing\nnumbness or tingling in the arms or legs\npounding in the ears\nshortness of breath\nswelling of the fingers, hands, feet, or lower legs\ntrouble thinking, speaking, or walking\ntroubled breathing at rest\nweight gain\nIncidence not known\nAbdominal cramping and/or burning (severe)\nabdominal pain\nbackache\nbloody, black, or tarry stools\ncough or hoarseness\ndarkening of skin\ndecreased vision\ndiarrhea\ndry mouth\neye pain\neye tearing\nfacial hair growth in females\nfainting\nfatigue\nfever or chills\nflushed, dry skin\nfractures\nfruit-like breath odor\nfull or round face, neck, or trunk\nheartburn and/or indigestion (severe and continuous)\nincreased hunger\nincreased thirst\nincreased urination\nloss of appetite\nloss of sexual desire or ability\nlower back or side pain\nmenstrual irregularities\nmuscle pain or tenderness\nmuscle wasting or weakness\nnausea\npain in back, ribs, arms, or legs\npainful or difficult urination\nskin rash\nsleeplessness\nsweating\ntrouble healing\ntrouble sleeping\nunexplained weight loss\nunusual tiredness or weakness\nvision changes\nvomiting\nvomiting of material that looks like coffee grounds\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nIncidence not known\nBlemishes on the skin\nbruising\ndry, scaly skin\nfeeling of constant movement of self or surroundings\nfull or bloated feeling\nincreased appetite\nincreased hair growth on the face, forehead, back, arms, and legs\nlarge, flat, blue, or purplish patches in the skin\npimples\npitting or depression of the skin at the injection site\nreddish purple lines on the arms, face, legs, trunk, or groin\nredness of the skin\nredness, swelling, tenderness, or pain at the injection site\nsensation of spinning\nsmall, red, or purple spots on the skin\nthin, fragile, or shiny skin\nthinning of the scalp hair\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Kenalog-40 side effects (more detail)\n','Triamcinolone injection is used to treat inflammation (swelling), allergic reactions, certain types of arthritis, gout, skin diseases, and many other medical problems. It is given to patients who are not able to take medicines by the mouth. This medicine is a corticosteroid (cortisone-like medicine or steroid).\nThis medicine is to be administered only by or under the immediate supervision of your doctor.\n','Your doctor will check your progress closely while you or your child are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.\nThis medicine contains benzyl alcohol which may cause serious reactions (e.g., gasping syndrome, low blood pressure, and metabolic acidosis) to newborn or premature infants. Discuss this with your doctor if you are concerned.\nThis medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after receiving this medicine.\nLet your doctor know if you or your child have any events causing unusual stress or anxiety in your life. Your doctor may give you oral corticosteroids.\nThis medicine may cause fluid retention (edema) in some patients. Carefully follow your doctor\'s instructions about any special diet (especially on salt intake).\nUsing too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and for patients who use large amounts for a long time. Talk to your doctor if you have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, pounding, or uneven heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.\nIt may be easier for you to get an infection while you or your child are receiving triamcinolone. Avoid crowded places or being near people who are sick. If you are exposed to chicken pox or measles, tell your doctor right away.\nTell your doctor if you or your child have recently spent time in a tropical climate or have unexplained diarrhea before receiving this medicine.\nTalk with your doctor before getting flu shots or other vaccines while you or your child are receiving this medicine because there are certain vaccines that you should not receive.\nCheck with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you or your child to have your eyes checked by an ophthalmologist (eye doctor).\nBefore you have any skin tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.\nDo not stop using this medicine without checking first with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping it completely\nThis medicine may cause slow growth. If your child is using this medicine, the doctor will need to keep track of your child\'s height and weight to make sure that your child is growing properly.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.\n',NULL),(457,'keppra','Take Keppra exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nKeppra oral is taken by mouth at the same time each day, with or without food.\nKeppra injection is given in a vein if you are unable to take the medicine by mouth.\nYour dose needs may change if you switch to a different brand, strength, or form of levetiracetam. A child\'s dose needs may change if the child gains or loses weight. Avoid medication errors by using only the brand, form, and strength your doctor prescribes.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nMeasure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).\nSwallow the extended-release tablet whole and do not crush, chew, or break it.\nYour kidney function may need to be tested.\nUse all seizure medications as directed. Do not change your dose or stop using a medicine without your doctor\'s advice.\nSeizures may increase if you stop using Keppra suddenly.. Ask your doctor before stopping the medicine.\nWear a medical alert tag or carry an ID card to let others know you have seizures.\nStore at room temperature away from moisture, heat, and light.\n Detailed Keppra dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include extreme drowsiness, agitation, aggression, shallow breathing, weakness, or fainting.\n','Other drugs may interact with levetiracetam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Keppra drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Keppra (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nunusual changes in mood or behavior (unusual risk-taking behavior, being irritable or talkative);\nconfusion, hallucinations, extreme drowsiness, feeling very weak or tired;\nloss of balance or coordination, problems with walking or movement;\na skin rash, no matter how mild;\neasy bruising, unusual bleeding; or\nfever, chills, weakness, or other signs of infection.\nCommon Keppra side effects may include:\ndizziness, drowsiness, tiredness, weakness;\nfeeling aggressive or irritable;\nloss of appetite;\nstuffy nose; or\ninfection.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Keppra side effects (more detail)\n','Keppra (levetiracetam) is an anti-epileptic drug, also called an anticonvulsant.\nKeppra is a prescription medicine used to treat certain types of seizures in people with epilepsy, including partial onset seizures, myoclonic seizures, and tonic-clonic seizures.\nWhen used for partial onset seizures:\nKeppra XR is for adults and children at least 12 years old.\nKeppra (immediate release tablets or oral solution) may be used in children as young as 1 month old.\nKeppra is also used with other seizure medications to treat tonic-clonic seizures in people who are at least 6 years old, and myoclonic seizures in people at least 12 years old.\nKeppra injection is used only as an alternative for patients when oral use is temporarily not possible.\n','Do not stop using Keppra without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using this medicine suddenly. You may need to use less and less before you stop the medication completely.\nSome people have thoughts about suicide when first taking this medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nWear a medical alert tag or carry an ID card stating that you take Keppra. Any medical care provider who treats you should know that you take seizure medication.\nKeppra may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Do not start or stop taking levetiracetam during pregnancy without your doctor\'s advice. Having a seizure during pregnancy could harm both the mother and the baby. Seizure control is very important during pregnancy and the benefits of preventing seizures may outweigh any risks posed by using this medicine.\nBefore taking this medicine\nYou should not use Keppra if you are allergic to levetiracetam.\nTo make sure Keppra is safe for you, tell your doctor if you have ever had:\nkidney disease (or if you are on dialysis);\ndepression or other mood problems;\nmental illness or psychosis; or\nsuicidal thoughts or actions.\nDo not give this medicine to a child without medical advice. Different brands of levetiracetam are for use only in children of certain ages.\nSome people have thoughts about suicide while taking Keppra. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nDo not start or stop seizure medication during pregnancy without your doctor\'s advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor if you become pregnant. Your dose needs may be different during pregnancy.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of levetiracetam on the baby.\nAsk a doctor if it is safe to breastfeed while using this medicine.\n','Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\n'),(458,'keppra-xr','This section provides information on the proper use of a number of products that contain levetiracetam.  It may not be specific to Keppra XR. Please read with care.\nTake this medicine only as directed by your doctor, to help your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change your dose without checking first with your doctor.\nThis medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.\nLevetiracetam may be taken with or without food or on a full or empty stomach. However, if your doctor tells you to take the medicine a certain way, take it exactly as directed. You should try to take this medicine at the same time each day.\nSwallow the tablet or the extended-release tablet whole. Do not break, crush, or chew it. There is an oral liquid form of this medicine if you or your child cannot swallow the tablets.\nElepsia™ XR extended-release tablet has a blue and white to off-white layer. If you do not see the blue or white, off-white layer, do not take the tablet.\nA part of the tablet may also pass into your stool. This is normal and is nothing to worry about.\nIf you are using the Spritam® tablet or the Spritam® tablet for suspension, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Place the tablet on your tongue and take a sip of water. After it has melted, swallow.\nYou may also add one whole Spritam® tablet for suspension to a small volume of liquid in a cup (1 tablespoon or enough to cover the medicine), and swirl gently. Swallow right away after it has dissolved. Then add a small volume of liquid to cup again, swirl gently, and swallow the liquid.\nMeasure the oral liquid with a marked measuring spoon, dropper, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. If you have any questions about this, ask your doctor or pharmacist.\nThis medicine can be used with other seizure medicines. Keep using all of your seizure medicines unless your doctor tells you otherwise.\nTake only the form of this medicine that your doctor prescribed. If you refill your prescription and your pills look different, do not take the medicine and tell your doctor or pharmacist right away.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor oral dosage form (extended-release tablets):\nFor treatment of partial-onset seizures:\nAdults and children 12 years of age and older and weighing 50 kilograms (kg) or more—At first, 1000 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren younger than 12 years of age—Use and dose must be determined by your doctor.\nFor oral dosage form (Keppra® solution or tablets):\nFor partial onset seizures:\nAdults and children 16 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 4 to 15 years of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 10 milligrams (mg) per kilogram (kg) of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per kg of body weight per day.\nChildren 6 months to 3 years of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 10 mg per kg of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 50 mg per kg of body weight per day.\nChildren 1 to 5 months of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 7 mg per kg of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 42 mg per kg of body weight per day.\nChildren younger than 1 month of age—Use and dose must be determined by your doctor.\nFor juvenile myoclonic seizures:\nChildren 12 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren younger than 12 years of age—Use and dose must be determined by your doctor.\nFor primary generalized tonic-clonic seizures:\nAdults and children 16 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 6 to 15 years of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 10 milligrams (mg) per kilogram (kg) of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per kg of body weight per day.\nChildren younger than 6 years of age—Use and dose must be determined by your doctor.\nFor oral dosage forms (Spritam® tablets, Spritam® tablets for suspension):\nFor partial onset seizures:\nAdults and children 4 years of age and older weighing over 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 4 years of age and older weighing 20 to 40 kg—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 250 mg 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1500 mg per day.\nChildren younger than 4 years of age and weighing less than 20 kg—Use is not recommended.\nFor juvenile myoclonic seizures:\nChildren 12 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren younger than 12 years of age—Use and dose must be determined by your doctor.\nFor primary generalized tonic-clonic seizures:\nAdults and children 6 years of age and older weighing over 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 6 years of age and older weighing 20 to 40 kg—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 250 mg 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1500 mg per day.\nChildren younger than 6 years of age and weighing less than 20 kg—Use is not recommended.\nMissed dose\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Keppra XR dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nMore common\nAggressive or angry\nanxiety\nchange in personality\nchills\ncough\ncrying\ndeep or fast breathing with dizziness\ndelusions of persecution, mistrust, suspiciousness, or combativeness\ndiarrhea\ndry mouth\nfalse or unusual sense of well-being\nfeeling of unreality\nfever\ngeneral feeling of discomfort or illness\nheadache\nhoarseness\nirregular heartbeat\nirritability\njoint pain\nloss of appetite\nlower back or side pain\nmental depression\nmuscle aches and pains\nnausea\nnumbness of the feet, hands, and around the mouth\npainful or difficult urination\nquick to react or overreact emotionally\nrapidly changing moods\nrestlessness\nsense of detachment from self or body\nshaking\nshivering\nsleepiness or unusual drowsiness\nsore throat\nstuffy or runny nose\nsweating\ntrouble sleeping\nunusual tiredness or weakness\nvomiting\nLess common\nBloody nose\nburning, crawling, itching, numbness, prickling, \"pins and needles\", or tingling feelings\nclumsiness or unsteadiness\ndiscouragement\ndizziness or lightheadedness\ndouble vision\nearache\nfeeling of constant movement of self or surroundings\nfeeling sad or empty\nincrease in body movements\nloss of bladder control\nloss of memory\nmood or mental changes\noutburst of anger\npain or tenderness around the eyes and cheekbones\nproblems with memory\nredness or swelling in the ear\nseizures\nsensation of spinning\nshakiness and unsteady walk\nshakiness in the legs, arms, hands, or feet\ntightness of the chest\ntrembling or shaking of the hands or feet\ntrouble concentrating\nunsteadiness, trembling, or other problems with muscle control or coordination\nIncidence not known\nAttempts at killing oneself\nbeing forgetful\nbleeding gums\nblistering, peeling, or loosening of the skin\nbloating\nblood in the urine or stools\nbloody, black, or tarry stools\nblurred vision\nchanges in vision\nchest pain\nconstipation\ndark urine\ndifficulty with moving\nfast heartbeat\nfever with or without chills\ngeneral feeling of tiredness or weakness\nhigh fever\nindigestion\nitching\nlight-colored stools\nmuscle pains or stiffness\npains in the stomach, side, or abdomen, possibly radiating to the back\npale skin\npinpoint red spots on the skin\nred skin lesions, often with a purple center\nred, irritated eyes\nskin rash, encrusted, scaly, and oozing\nsores, ulcers, or white spots on the lips or in the mouth\nstomach pain, continuing\nswollen glands\nswollen joints\nthoughts or attempts at killing oneself\ntrouble with balance\ntwitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs\nuncontrolled jerking or twisting movements of the hands, arms, or legs\nuncontrolled movements of the lips, tongue, or cheeks\nunexplained bleeding or bruising\nunusual bleeding or bruising\nupper right abdominal or stomach pain\nweight loss\nyellow eyes or skin\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nMore common\nLoss of strength or energy\nmuscle pain or weakness\npain\ntender, swollen glands in the neck\ntrouble swallowing\nunusual weak feeling\nvoice changes\nLess common\nBody aches or pain\nburning, dry, or itching eyes\nchange in the color of the skin\ncongestion\ncough increased\nsneezing\nIncidence not known\nHair loss or thinning of the hair\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Keppra XR side effects (more detail)\n','Levetiracetam is used to control certain types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to use it.\nThis medicine is available only with your doctor\'s prescription.\n','It is very important that your doctor check your or your child\'s progress at regular visits, especially for the first few months you or your child are using this medicine. This is necessary to allow dose adjustments and to reduce any unwanted effects.\nLevetiracetam may cause changes in mood or behavior, problems with coordination, or unusual tiredness or weakness. Tell your doctor right away if you or your child start to feel depressed, anxious, angry, getting upset easily, restless, or have thoughts about hurting yourself. Report any unusual thoughts or behavior that trouble you, especially if they are new or getting worse quickly.\nThis medicine may cause some people to become dizzy, drowsy, tired, or less alert than they are normally. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.\nThis medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.\nSerious skin reactions can occur with this medicine. Check with your doctor right away if you or your child have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.\nDo not stop using levetiracetam without first checking with your doctor. Stopping the medicine suddenly may cause your seizures to return or to occur more often. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely.\nMake sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.\n',NULL),(459,'kesimpta','See the detailed Instructions for Use that comes with Kesimpta for information about how to prepare and inject a dose of Kesimpta and how to properly throw away (dispose of) used pens or prefilled syringes.\nUse Kesimpta exactly as your healthcare provider tells you to use it.\nKesimpta is given as an injection under your skin (subcutaneous injection), in your thigh or stomach-area (abdomen) by you or a caregiver. A caregiver may also give you an injection in your upper outer arm.\nYour healthcare provider will show you how to prepare and inject Kesimpta the right way before you use it for the first time.\nDo not inject into areas where the skin is tender, bruised, red, scaly or hard. Avoid areas with moles, scars or stretch marks.\nThe initial dosing is 20 mg of Kesimpta given by subcutaneous injection at Weeks 0, 1, and 2. There is no injection at Week 3. Starting at Week 4 and then every month, the recommended dose is 20 mg of Kesimpta administered by subcutaneous injection.\nIf you miss an injection at Week 0, 1, or 2, talk to your healthcare provider. If you miss a monthly injection, give it as soon as possible without waiting until the next scheduled dose. After that, use your injections a month apart.\n Detailed Kesimpta dosage information\n',NULL,'Kesimpta may cause serious side effects, including:\nSee Important information\nInjection-related reactions. Injection-related reactions is a common side effect of Kesimpta. Injecting this medicine can cause injection-related reactions that can happen within 24 hours (1 day) following the first injections and with later injections. Talk with your healthcare provider if you have any of these signs and symptoms:\nat or near the injection site: redness of the skin, swelling, itching and pain or\nthat may happen when certain substances are released in your body: fever, headache, pain in the muscles, chills, and tiredness.\nLow immunoglobulins. Kesimpta may cause a decrease in some types of antibodies. Your healthcare provider will do blood tests to check your blood immunoglobulin levels.\nThe most common side effects of Kesimpta include:\nupper respiratory tract infection, with symptoms such as sore throat and runny nose, and headache. See Important information\nheadache\nThese are not all the possible side effects of Kesimpta. Call your doctor for medical advice about side effects.\nYou may report side effects to FDA at 1-800-FDA-1088.\n Kesimpta side effects (more detail)\nHow should I store Kesimpta?\nStore Kesimpta in a refrigerator between 36°F to 46°F (2°C to 8°C).\nKeep Kesimpta in the original carton until ready for use to protect from light.\nDo not freeze.\nDo not shake.\nKeep Kesimpta and all medicines out of the reach of children.\nGeneral information about the safe and effective use of Kesimpta.\nMedicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms that you have. It may harm them.You can ask your pharmacist or healthcare provider for information that is written for health professionals.\nWhat are the ingredients in Kesimpta?\nActive ingredient: ofatumumab\nInactive ingredients: Sensoready pen and prefilled syringe: arginine, disodium edetate, polysorbate 80, sodium acetate trihydrate, sodium chloride, and Water for Injection. Hydrochloric acid may be added.\n','Kesimpta (ofatumumab) is a prescription medicine used to treat adults with relapsing forms of multiple sclerosis (MS) including:\nclinically isolated syndrome\nrelapsing-remitting disease\nactive secondary progressive disease\nIt is not known if Kesimpta is safe or effective in children.\n','Kesimpta can cause serious side effects, including:\nInfections. Serious infections can happen during treatment with Kesimpta. If you have an active infection, your healthcare provider should delay your treatment until your infection is gone. Kesimpta taken before or after other medicines that weaken the immune system may increase your risk of getting infections.\nTell your healthcare provider right away if you have any infections or get any symptoms, including painful and frequent urination, nasal congestion, runny nose, sore throat, fever, chills, cough, or body aches.\nHepatitis B virus (HBV) reactivation. Before starting treatment, your healthcare provider will do blood tests to check for HBV. If you have ever had HBV infection, the HBV may become active again during or after treatment. Hepatitis B virus becoming active again (called reactivation) may cause serious liver problems, including liver failure or death. You should not receive Kesimpta if you have active hepatitis B liver disease. Your healthcare provider will monitor you for HBV infection during and after you stop using this medicine.\nTell your healthcare provider right away if you get worsening tiredness or yellowing of your skin or white part of your eyes during treatment.\nProgressive Multifocal Leukoencephalopathy (PML). PML may happen with Kesimpta. PML is a rare, serious brain infection caused by a virus that may get worse over days or weeks. PML can result in death or severe disability. Tell your healthcare provider right away if you have any new or worsening neurologic signs or symptoms. These may include weakness on one side of your body, loss of coordination in arms and legs, vision problems, changes in thinking and memory which may lead to confusion and personality changes.\nWeakened immune system. Kesimpta taken before or after other medicines that weaken the immune system could increase your risk of getting infections.\nWho should not take Kesimpta?\nDo not use Kesimpta if you:\nhave active hepatitis B virus infection.\n',NULL),(460,'ketamine','Usual Adult Dose for Anesthesia:\nIV:-Induction: 1 to 4.5 mg/kg IV; alternatively, 1 to 2 mg/kg IV at a rate of 0.5 mg/kg/min; (2 mg/kg dose provides 5 to 10 minutes of surgical anesthesia within 30 seconds)-Maintenance: The maintenance dose should be adjusted according to the patient\'s anesthetic needs and whether an additional anesthetic is employed.  Increments of one-half to the full induction dose may be repeated as needed for maintenance of anesthesia.IM:-Induction: 6.5 to 13 mg/kg IM; (9 to 13 mg/kg IM provides 12 to 25 minutes of surgical anesthesia)-Maintenance: The maintenance dose should be adjusted according to the patient\'s anesthetic needs and whether an additional anesthetic is employed.  Increments of one-half to the full induction dose may be repeated as needed for maintenance of anesthesia.Comments:-This drug should be administered slowly over a period of 60 seconds (more rapid administration may result in respiratory depression and enhanced pressor response).-The larger the total dose, the longer will be complete recovery.-Because of rapid induction following the initial IV injection, the patient should be in a supported position during administration.\nUsual Pediatric Dose for Anesthesia:\n16 years and older: See adult dosing\n Detailed Ketamine dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','If you are using any drugs that make you sleepy or slow your breathing, it may take you longer to recover from anesthesia with ketamine. This includes opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nOther drugs may affect ketamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ketamine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nTell your caregivers at once if you have any of these serious side effects within 24 hours after you receive ketamine: severe confusion, hallucinations, unusual thoughts, or extreme fear.\nCall your doctor at once if you have:\npainful or difficult urination, increased urination, loss of bladder control, blood in your urine;\na light-headed feeling, like you might pass out;\nslow heart rate, weak or shallow breathing; or\njerky muscle movements that may look like convulsions.\nCommon side effects may include:\ndream-like feeling;\nblurred vision, double vision;\ndizziness, drowsiness;\nnausea, vomiting, loss of appetite; or\nsleep problems (insomnia).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ketamine side effects (more detail)\n','Ketamine is used to put you to sleep for surgery and to prevent pain and discomfort during certain medical tests or procedures.\nKetamine may also be used for purposes not listed in this medication guide.\n','You should not be treated with ketamine if you have untreated or uncontrolled hypertension (high blood pressure).\nTell your caregivers at once if you have serious side effects within 24 hours after you receive ketamine, including severe confusion, hallucinations, unusual thoughts, or extreme fear.\nBefore taking this medicine\nYou should not receive ketamine if you are allergic to it, or if you have untreated or uncontrolled hypertension (high blood pressure).\nTell your doctor if you have ever had:\nheart disease;\nhigh blood pressure;\nalcoholism; or\nif you drink large amounts of alcohol.\nKetamine may be harmful to an unborn baby. Tell your doctor if you are pregnant.\nAnesthesia medicine may affect brain development in a child under 3, or an unborn baby whose mother receives  ketamine during late pregnancy. These effects may be more likely when the anesthesia is used for 3 hours or longer, or used for repeated procedures. Effects on brain development could cause learning or behavior problems later in life.\nNegative brain effects from anesthesia have been seen in animal studies. However, studies in human children receiving single short uses of anesthesia have not shown a likely effect on behavior or learning. More research is needed.\nIn some cases, your doctor may decide to postpone a surgery or procedure based on these risks. Treatment may not be delayed in the case of life-threatening conditions, medical emergencies, or surgery needed to correct certain birth defects.\nAsk your doctor for information about all medicines that will be used during your surgery or procedure. Also ask how long the procedure will last.\nIt may not be safe to breast-feed shortly after receiving this medicine. Ask your doctor about any risk.\nHow is ketamine given?\nKetamine is injected into a muscle, or as an infusion into a vein. You will receive this injection in a clinic or hospital setting.\nYour breathing, blood pressure, heart function, and other vital signs will be watched closely while you are receiving ketamine.\nYou may feel strange or slightly confused when you first come out of anesthesia. Tell your caregivers if these feelings are severe or unpleasant.\nWhat happens if I miss a dose?\nSince ketamine is usually given for anesthesia, you are not likely to be on a dosing schedule.\nWhat happens if I overdose?\nSince ketamine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. Your vital signs will be closely watched while you are under anesthesia to make sure the medication is not causing any harmful effects.\n',' ketamine may impair your thinking or reactions. You will probably not be allowed to drive yourself home after your surgery or medical procedure. Avoid driving or operating machinery for at least 24 hours after you have received ketamine.\n'),(461,'ketoconazole','Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using ketoconazole.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYou may need to use this medicine for up to 6 months.\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Ketoconazole will not treat a viral infection such as the flu or a common cold.\nWhile using ketoconazole, you may need frequent blood tests to check your liver function.\nStore at room temperature away from moisture, heat, and light.\nDo not share this medicine with another person, even if they have the same symptoms you have.\n Detailed Ketoconazole dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Some medicines can make it harder for your body to absorb ketoconazole. If you take an antacid, take it 1 hour before or 2 hours after you take ketoconazole. Tell your doctor if you also take a stomach acid reducer, such as Nexium, Prevacid, Prilosec, Protonix, Zantac, and others.\nSometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nKetoconazole can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\nMany drugs can affect ketoconazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ketoconazole drug interactions (more detail)\nDoes Ketoconazole interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, fever, chest pain, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nunusual weakness or tiredness, dizziness, nausea, and vomiting; or\nliver problems--upper stomach pain, fever, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nnausea, diarrhea, stomach pain\nbreast swelling;\nheadache, dizziness; or\nabnormal liver function tests.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ketoconazole side effects (more detail)\n','Ketoconazole is an antifungal medication that is used to treat certain infections caused by fungus.\n ketoconazole should be used only when you cannot use other antifungal medications. Ketoconazole can cause serious harm to your liver that may result in liver transplant or cause death.\nKetoconazole is not for use in treating fungal infections of the fingernails or toenails. This medicine is also not for use in treating prostate cancer or Cushing syndrome.\nKetoconazole may also be used for purposes not listed in this medication guide.\n','This medicine should be used only when you cannot use other antifungal medications. Ketoconazole can cause serious harm to your liver that may result in liver transplant or cause death.\nCall your doctor at once if you have any signs of liver damage, such as nausea, vomiting, stomach pain, fever, tiredness, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).\nTell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.\nKetoconazole can also cause a serious heart problem. Call your doctor right away if you have fast or pounding heartbeats, shortness of breath, and sudden dizziness.\nBefore taking this medicine\nYou should not use ketoconazole if you are allergic to it, or if you have liver disease.\nSome medicines can cause unwanted or dangerous effects when used with ketoconazole. Your doctor may change your treatment plan if you also use:\ncisapride;\ncolchicine;\nirinotecan;\nmethadone;\ntolvaptan;\nantipsychotic medicine--pimozide, lurasidone;\ncholesterol medication--lovastatin, simvastatin, and others;\nergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine;\nheart medication--disopyramide, dofetilide, dronedarone, eplerenone, felodipine, nisoldipine, quinidine, ranolazine; or\na sedative--alprazolam, midazolam, or triazolam.\nTell your doctor if you have ever had:\nliver problems;\nlong QT syndrome (in you or a family member); or\nproblems with your adrenal gland.\nIt is not known whether  ketoconazole will harm an unborn baby. Tell your doctor if you are pregnant.\nYou should not breast-feed while using this medicine.\nDo not give this medicine to a child without medical advice.\n','Do not drink alcohol. Dangerous side effects could occur.\nKetoconazole could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.\n'),(462,'ketoconazole-topical',NULL,'Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\nDoes Ketoconazole topical interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nburning, stinging, or severe irritation after using this medicine;\nredness, pain, or oozing of treated skin; or\nshortness of breath.\nCommon side effects may include:\nthinning hair;\nchanges in the color or texture of your hair;\ndry skin; or\nmild itching.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ketoconazole topical side effects (more detail)\n','Ketoconazole topical (for the skin) is an antifungal medicine used to treat infections such as athlete\'s foot, jock itch, ringworm, and seborrhea (dry, flaking skin or dandruff).\nKetoconazole topical is also used to treat a fungal infection called pityriasis, which causes scaly discolored patches on the skin of the neck, chest, arms, or legs.\nKetoconazole topical may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\n','Do not get  ketoconazole topical in your eyes. If contact does occur, rinse with water.\nAvoid covering treated skin areas with tight-fitting, synthetic clothing (such as nylon or polyester) that doesn\'t allow air to circulate to your skin. If you are treating your feet, wear clean cotton socks and sandals or shoes that allow for air circulation. Keep your feet as dry as possible.\nYou may need to avoid sunlight if you are treating pityriasis. Follow your doctor\'s instructions.\nAvoid using skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.\nAvoid using other medications on the areas you treat with ketoconazole topical unless your doctor tells you to.\n'),(463,'ketoprofen','Use exactly as directed on the label, or as prescribed by your doctor. Use the lowest dose that is effective in treating your condition.\nKetoprofen may be taken with food or milk if it upsets your stomach.\nSwallow the capsule whole and do not crush, chew, break, or open it.\nIf you use  ketoprofen long-term, you may need frequent medical tests.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Ketoprofen dosage information\nWhat happens if I miss a dose?\nSince ketoprofen is used when needed, you may not be on a dosing schedule. Skip any missed dose if it\'s almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.\n','Ask your doctor before using ketoprofen if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.\nAsk a doctor or pharmacist before using ketoprofen with any other medications, especially:\nlithium;\nmethotrexate;\nprobenecid;\na blood thinner (warfarin, Coumadin, Jantoven);\nheart or blood pressure medication, including a diuretic or \"water pill\"; or\nsteroid medicine (such as prednisone).\nThis list is not complete. Other drugs may affect ketoprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Ketoprofen drug interactions (more detail)\nDoes Ketoprofen interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (sneezing, runny or stuffy nose, hives, wheezing or trouble breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nGet emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.\nStop using ketoprofen and call your doctor at once if you have:\nshortness of breath (even with mild exertion);\nswelling or rapid weight gain;\nnausea, diarrhea, flu-like symptoms (fever, swollen glands, muscle aches, severe weakness);\na skin rash, no matter how mild;\nsigns of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nliver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nkidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or\nlow red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.\nCommon side effects may include:\nheartburn, stomach pain, gas, nausea, vomiting;\ndiarrhea, constipation; or\ndizziness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ketoprofen side effects (more detail)\n','Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain or inflammation caused by arthritis.\nThe ketoprofen regular capsule is also used to treat mild to moderate pain, or menstrual pain.\nOnly ketoprofen extended-release capsules are used for treating arthritis. This form of ketoprofen will not work fast enough to treat acute (immediate) pain.\nKetoprofen may also be used for purposes not listed in this medication guide.\n','Ketoprofen can increase your risk of fatal heart attack or stroke. Do not use  ketoprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Ketoprofen may also cause stomach or intestinal bleeding, which can be fatal.\nBefore taking this medicine\nKetoprofen can increase your risk of fatal heart attack or stroke, even if you don\'t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nKetoprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using ketoprofen, especially in older adults.\nYou should not use ketoprofen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.\nAsk a doctor or pharmacist if this medicine is safe to use if you have ever had:\nheart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;\na heart attack, stroke, or blood clot;\nstomach ulcers or bleeding;\nasthma;\nliver or kidney disease; or\nfluid retention.\nIf you are pregnant, you should not take ketoprofen unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.\nAsk a doctor before using this medicine if you are breastfeeding.\nKetoprofen is not approved for use by anyone younger than 18 years old.\n','Do not take ketoprofen regular capsules and extended-release capsules at the same time.\nAvoid drinking alcohol. It may increase your risk of stomach bleeding.\nAsk a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to ketoprofen (such as aspirin, ibuprofen, or naproxen).\n'),(464,'ketorolac',NULL,NULL,NULL,NULL,NULL,NULL),(465,'ketorolac-ophthalmic','Usual Adult Dose for Corneal Refractive Surgery:\n0.4% Ophthalmic Solution: Instill 1 drop in the operated eye(s) four times a day as needed for pain and burning/stinging for up to 4 days following corneal refractive surgeryUse: For the relief of ocular pain and burning/stinging following corneal refractive surgery\nUsual Adult Dose for Postoperative Ocular Inflammation:\n0.45% Ophthalmic Solution: Instill 1 drop in the affected eye(s) twice a day beginning 1 day prior to cataract surgery, continuing on the day of surgery, and through the first 2 weeks of the postoperative period0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day beginning 24 hours after cataract surgery and continue through the first 2 weeks of the postoperative periodUse: For the treatment of pain and inflammation following cataract surgery\nUsual Adult Dose for Seasonal Allergic Conjunctivitis:\n0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a dayUse: For the temporary relief of ocular itching due to seasonal allergic conjunctivitis\nUsual Pediatric Dose for Corneal Refractive Surgery:\n3 years or older:0.4% Ophthalmic Solution: Instill 1 drop in the operated eye(s) four times a day as needed for pain and burning/stinging for up to 4 days following corneal refractive surgeryUse: For the relief of ocular pain and burning/stinging following corneal refractive surgery\nUsual Pediatric Dose for Postoperative Ocular Inflammation:\n2 years or older:0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day beginning 24 hours after cataract surgery and continue through the first 2 weeks of the postoperative periodUses: For the treatment of pain and inflammation following cataract surgery\nUsual Pediatric Dose for Seasonal Allergic Conjunctivitis:\n2 years or older:0.5% Ophthalmic Solution: Instill 1 drop in the affected eye(s) four times a day for the relief of ocular itchingUse: For the temporary relief of ocular itching due to seasonal allergic conjunctivitis\n Detailed Ketorolac ophthalmic dosage information\n','It is not likely that other drugs you take orally or inject will have an effect on ketorolac used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n Ketorolac ophthalmic drug interactions (more detail)\nDoes Ketorolac ophthalmic interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere burning, stinging, or itching of your eyes;\na wound that will not heal;\neye pain, redness, or watering;\nvision changes, increased sensitivity to light;\nwhite patches on your eyes; or\ncrusting or drainage from your eyes.\nCommon side effects may include:\nmild eye pain, stinging, or redness;\nblurred vision;\nwatery eyes;\nswollen or puffy eyelids; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ketorolac ophthalmic side effects (more detail)\n','Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body.\nKetorolac ophthalmic (for the eye) is used to relieve eye itching caused by seasonal allergies.\nKetorolac ophthalmic is also used to reduce swelling, pain, and burning or stinging after cataract surgery or corneal refractive surgery.\nKetorolac ophthalmic may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use  ketorolac ophthalmic if you are allergic to ketorolac. Tell your doctor if you are allergic to any other NSAIDs, such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nTo make sure ketorolac ophthalmic is safe for you, tell your doctor if you have:\na bleeding or blood-clotting disorder;\ndiabetes;\narthritis;\nglaucoma;\ndry eye syndrome; or\na condition for which you take a blood thinner such as warfarin (Coumadin, Jantoven).\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.\nIt is not known whether ketorolac ophthalmic passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nDo not give this medicine to a child without medical advice.\nHow should I use ketorolac ophthalmic?\nFollow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nKetorolac ophthalmic is used 2 to 4 times per day, depending on the condition you are treating. Follow your doctor\'s dosing instructions very carefully. Prolonged use of NSAID eye drops can lead to serious damage to your eyesight.\nFor cataract surgery you will begin using the eye drops 1 day before surgery and continue for up to 2 weeks afterward. For corneal refractive surgery the usual dosage is 4 times daily for up to 4 days after surgery.\nDo not use ketorolac ophthalmic while you are wearing contact lenses.\nWash your hands before using the eye drops.\nTo apply the eye drops:\nTilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.\nClose your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.\nUse only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.\nIf using this medicine after single-eye surgery, use the drops only in the eye you are having surgery on.\nWait at least 10 minutes before using any other eye drops your doctor has prescribed.\nDo not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.\nDo not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.\nEach single-use vial (bottle) of this medicine is for use in one eye only. Throw away after one use, even if there is still some medicine left in the vial.\nStore at room temperature away from moisture, heat, and light. Do not freeze. Keep the bottle tightly closed when not in use. If your medicine vials come in a foil pouch, store the vials inside the pouch and fold the ends closed.\nWhat happens if I miss a dose?\nUse the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.\nWhat happens if I overdose?\nAn overdose of ketorolac ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\n','While using this medication, do not wear any contact lens that has not been approved by your doctor.\nDo not use other eye medications unless your doctor tells you to.\n'),(466,'ketorolac-tromethamine',NULL,NULL,NULL,NULL,NULL,NULL),(467,'ketotifen','Make certain your health care professional knows if you are on any special diet, such as a low-sugar diet. The syrup contains carbohydrates.\nKetotifen is used to help prevent asthma attacks. It will not relieve an asthma attack that has already started.\nKetotifen must be taken continuously in order to be effective.\nContinue taking your current asthma medications until instructed otherwise by your doctor.\nKetotifen may be taken with or without food.\nDosing\nThe dose of ketotifen will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of ketotifen. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor oral dosage form (tablets and syrup):\nFor asthma:\nAdults and children 3 years of age and older—The usual dose is 1 milligram (mg) (1 tablet or 5 milliliters [mL] of syrup) twice daily, once in the morning and once in the evening.\nInfants and children from 6 months to 3 years of age—Dose is based on body weight and must be determined by the doctor. It is usually 0.25 mL (50 mcg or 0.05 mg) of syrup per kilogram (kg) (110 micrograms [mcg] or 0.110 mg per pound) of body weight twice daily, once in the morning and once in the evening.\nMissed dose\nIf you miss a dose of ketotifen, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\n Detailed Ketotifen ophthalmic dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor as soon as possible if any of the following side effects occur:\nLess common\nChills\ncough\ndiarrhea\nfever\ngeneral feeling of discomfort or illness\nheadache\njoint pain\nloss of appetite\nmuscle aches and pains\nnausea\nrunny nose\nshivering\nsore throat\nsweating\ntrouble sleeping\nunusual tiredness or weakness\nvomiting\nRare\nAbdominal or stomach pain\nblistering, itching, peeling, or redness of skin\nbloody or cloudy urine\nclay-colored stools\nconvulsions\ndark urine\ndifficult, burning, or painful urination\ndizziness\nfrequent urge to urinate\nmuscle spasm or jerking of all extremities\nrash\nsudden loss of consciousness\nunpleasant breath odor\nvomiting of blood\nyellow eyes or skin\nSymptoms of overdose\nGet emergency help immediately if any of the following symptoms of overdose occur:\nBlurred vision\nconfusion\nconvulsions\ndisorientation\ndizziness\ndrowsiness (severe)\nfaintness or lightheadedness when getting up from a lying or sitting position\nfast, pounding, or irregular heartbeat or pulse\nhyperexcitability\nloss of consciousness\npalpitations\nsweating\nunusual tiredness or weakness\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nMore common\nWeight gain\nLess common or rare\nBloody nose\ndrowsiness\ndryness of mouth\nexcitation\nincreased appetite\nirritability\nnervousness\nswelling of eyelids\nunexplained nosebleeds\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Ketotifen ophthalmic side effects (more detail)\n','Ketotifen is a type of asthma medication which, when taken every day and used along with other antiasthma medications, may reduce the frequency, severity, and duration of asthma symptoms or attacks in children. It may also lead to a reduction in daily requirements of other antiasthma medications. Ketotifen is not effective for the prevention or treatment of acute asthma attacks. Ketotifen works by inhibiting certain substances in the body that are known to cause inflammation and symptoms of asthma.\nKetotifen is available only with your doctor\'s prescription.\n','It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your symptoms worsen, you should check with your doctor.\nKetotifen may cause some people to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to ketotifen before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.\nKetotifen may cause some people to become excited, irritable, or nervous or to have trouble in sleeping. These are symptoms of central nervous system stimulation and are especially likely to occur in children.\nFor patients with diabetes:\nThe syrup form of ketotifen may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests or if you have any questions, check with your doctor.\n',NULL),(468,'ketotifen-ophthalmic','Usual Adult Dose for Allergic Conjunctivitis:\nInstill 1 drop in the affected eye(s) 2 times a dayComments: May administer eye drops every 8 to 12 hours, but should not administer more than twice a day.Use: For the treatment of itching related to pollen, ragweed, grass, animal hair and dander.\nUsual Pediatric Dose for Allergic Conjunctivitis:\nAge: 3 years and olderInstill 1 drop in the affected eye(s) 2 times a dayComments: May administer eye drops every 8 to 12 hours, but should not administer more than twice a day.Use: For the treatment of itching related to pollen, ragweed, grass, animal hair and dander.\n Detailed Ketotifen ophthalmic dosage information\n','It is not likely that other drugs you take orally or inject will have an effect on ketotifen used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\nDoes Ketotifen ophthalmic interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using ketotifen ophthalmic and call your doctor at once if you have:\nredness, drainage, eyelid swelling, or other signs of infection;\neye pain;\nvision changes; or\nsevere itching of the eyes worse than before using the medication.\nCommon side effects may include:\nmild burning, stinging, or eye irritation;\ndryness of the eyes; or\nincreased sensitivity to light.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ketotifen ophthalmic side effects (more detail)\n','Ketotifen is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.\nKetotifen ophthalmic (for use in the eyes) is used to treat itching of the eyes caused by allergy to dust, pollen, animals, or other allergens.\nKetotifen ophthalmic may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use ketotifen ophthalmic if you are allergic to it, or if you have:\nan untreated eye infection; or\neye irritation caused by wearing contact lenses.\nKetotifen ophthalmic is not approved for use by anyone younger than 3 years old.\nHow should I use ketotifen ophthalmic?\nUse exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.\nDo not use  ketotifen ophthalmic while wearing contact lenses. Ketotifen ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 10 minutes after using this medicine before putting in your contact lenses.\nWash your hands before using the eye drops.\nTo apply the eye drops:\nTilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.\nClose your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.\nUse only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.\nWait at least 10 minutes before using any other eye drops your doctor has prescribed.\nDo not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.\nDo not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.\nCall your doctor if your eye itching does not improve, or if it lasts longer than 72 hours.\nStore at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.\nWhat happens if I miss a dose?\nUse the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.\nWhat happens if I overdose?\nAn overdose of ketotifen ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\n','Do not use other eye medications unless your doctor tells you to.\n'),(469,'kevzara','Usual Adult Dose for Rheumatoid Arthritis:\n200 mg subcutaneously every 2 weeks\nComments:\n-This drug may be used as monotherapy or in combination with methotrexate (MTX) or other conventional DMARDs.\n-Test patients for latent tuberculosis (TB); if positive, consider treating for TB prior to initiating therapy.\n-Avoid using this drug with biological DMARDs because of the possibility of increased immunosuppression and increased risk of infection; concurrent use with biological DMARDs such as TNF antagonists, IL-1R antagonists, anti-CD20 monoclonal antibodies and selective co-stimulation modulators has not been studied.\n-Avoid use in patients with active infections.\nUse: For the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs (DMARDs)\n Detailed Kevzara dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nTell your doctor about all your current medicines. Many drugs can interact with sarilumab, especially:\nany other medicines to treat rheumatoid arthritis, such as abatacept, adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, rituximab, tocilizumab, or tofacitinib.\nThis list is not complete and many other drugs may affect Kevzara. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Kevzara drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kevzara: hives; chest pain, difficult breathing, feeling like you might pass out; swelling of your face, lips, tongue, or throat.\nSerious and sometimes fatal infections may occur during treatment with Kevzara. Stop using this medicine and call your doctor right away if you have signs of infection such as:\nfever, chills, sweating, body aches;\ncough with bloody mucus;\nfeeling short of breath;\ndiarrhea, stomach pain, weight loss;\nsores on your skin;\npain or burning when you urinate; or\nfeeling very tired.\nAlso call your doctor at once if you have signs of perforation (a hole or tear) in your stomach or intestines:\nfever;\nongoing stomach pain; or\na change in bowel habits.\nCommon Kevzara side effects may include:\nrunny or stuffy nose, sinus pain, sore throat;\nabnormal liver function tests;\npainful urination; or\nskin redness where an injection was given.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kevzara side effects (more detail)\n','Kevzara (sarilumab) reduces the effects of a substance in the body that can cause inflammation.\nKevzara is used to treat moderate to severe rheumatoid arthritis in adults. Itis sometimes given together with other arthritis medicines.\nKevzara is usually given after other medications have been tried without successful treatment of symptoms.\nKevzara is also being studied in clinical trials as a potential treatment for patients who are severely or critically ill with COVID-19.\n','Kevzara affects your immune system. You may get infections more easily, even serious or fatal infections. Tell your doctor if you have a fever, chills, tiredness, cough, diarrhea, stomach pain, weight loss, skin sores, or painful urination.\nKevzara may cause you to have a tear in your stomach or intestines. This is more likely if you have diverticulitis or a stomach ulcer, or if you also take steroids, methotrexate, or an NSAID (nonsteroidal anti-inflammatory drug). Call your doctor right away if you have a fever and ongoing stomach pain.\nBefore and during your treatment with Kevzara, you will need frequent blood tests. Your treatment may be delayed or stopped based on the results of these tests.\nBefore taking this medicine\nYou should not use Kevzara if you are allergic to sarilumab.\nTell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.\nTo make sure Kevzara is safe for you, tell your doctor if you have ever had:\nan active or chronic infection;\ndiabetes;\nHIV or AIDS;\na weak immune system;\nhepatitis or other liver problems;\nstomach pain, diverticulitis, or stomach or intestinal ulcers;\ncancer; or\nif you have received or are scheduled to receive any vaccines.\nUsing Kevzara may increase your risk of developing certain types of cancers. Ask your doctor about this risk.\nIt is not known whether sarilumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of sarilumab on the baby.\nYou should not breast-feed while using Kevzara.\nHow should I take Kevzara?\nKevzara is injected under the skin, usually given once every 2 weeks. A healthcare provider may teach you how to properly use the medication by yourself.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy or has particles in it. Call your pharmacist for new medicine.\nKevzara affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.\nStore this medicine in its original container in a refrigerator. Protect from light. Do not shake or freeze the medicine. Keep Kevzara cold even while traveling.\nBefore injecting your dose, take the medicine out of the refrigerator and let it reach room temperature (for 30 minutes if using the prefilled syringe, or for 60 minutes if using the injection pen). Once at room temperature, the medicine must be used within 14 days.\nEach prefilled syringe or injection pen is for one use only. Throw it away after one use, even if there is still medicine left inside.\nPlace used needles, syringes, or injection pens in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n','Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\nDo not receive a \"live\" vaccine while using Kevzara, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\n'),(470,'keytruda','Usual Adult Dose for Melanoma -- Metastatic:\nUnresectable or metastatic melanoma:\n200 mg IV over 30 minutes every 3 weeks until disease progression or unacceptable toxicity\nAdjuvant treatment of melanoma:\n200 mg IV over 30 minutes every 3 weeks until disease recurrence, unacceptable toxicity, or for up to 12 months in patients without disease recurrence\nUses:\n-Treatment of patients with unresectable or metastatic melanoma\n-Adjuvant treatment of patients with melanoma with involvement of lymph node(s) following complete resection\nUsual Adult Dose for Non-Small Cell Lung Cancer:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUses:\nSINGLE AGENT:\n-For the first-line treatment of patients with non-small cell lung cancer (NSCLC) expressing PD-L1 (Tumor Proportion Score [TPS] 1% or greater) as determined by an FDA-approved test with no EGFR or ALK genomic tumor aberrations, and is stage III where patients are not candidates for surgical resection or definitive chemoradiation OR metastatic\n-For the treatment of patients with metastatic NSCLC whose tumors express PD-L1 (TPS 1% or greater) as determined by an FDA-approved test with disease progression on or after platinum-containing chemotherapy; patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving this drug\nCOMBINATION THERAPY:\n-In combination with pemetrexed and platinum chemotherapy for first-line treatment of metastatic nonsquamous non-small cell lung cancer (NSCLC) with no EGFR or ALK genomic tumor aberrations\n-In combination with carboplatin and either paclitaxel or paclitaxel protein-bound for first-line treatment of patients with metastatic squamous NSCLC\nUsual Adult Dose for Small Cell Lung Cancer:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy and at least one prior line of therapy\nUsual Adult Dose for Head and Neck Cancer:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nComments:\n-When administering this drug in combination with chemotherapy, administer this drug prior to chemotherapy when given on the same day.\n-Refer to the Prescribing Information for the chemotherapy agents administered in combination with this drug for recommended dosing information.\nUses:\n-As a single agent for first line treatment of patients with metastatic or unresectable recurrent head and neck squamous cell cancer (HNSCC) whose tumors express PD-L1 (Combined Positive Score [CPS] greater than or equal to 1) as determined by an FDA-approved test\n-As a single agent for treatment of patients with recurrent or metastatic HNSCC with disease progression on or after platinum-containing chemotherapy\n-In combination with platinum and fluorouracil (FU) for first-line treatment of patients with metastatic or with unresectable, recurrent head and neck squamous cell carcinoma (HNSCC)\nUsual Adult Dose for Hodgkin\'s Disease:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of patients with refractory classical Hodgkin lymphoma (cHL), or who have relapsed after 3 or more prior lines of therapy\nUsual Adult Dose for Urothelial Carcinoma:\nLocally advanced or metastatic urothelial carcinoma:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nHigh-risk BCG-unresponsive non-muscle invasive bladder cancer:\n200 mg IV over 30 minutes every 3 weeks until persistent or recurrent high-risk NMIBC, disease progression or unacceptable toxicity, or up to 24 months in patients without disease progression\nUses:\n-For the treatment of patients with locally advanced or metastatic urothelial carcinoma who are not eligible for cisplatin-containing chemotherapy and whose tumors express PD-L1 10 or greater) as determined by an FDA-approved test, or in patients who are not eligible for any platinum-containing chemotherapy regardless of PD-L1 status.\n-For the treatment of patients with locally advanced or metastatic urothelial\ncarcinoma who have disease progression during or following platinum-containing chemotherapy or within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.\n-For the treatment of patients with Bacillus Calmette-Guerin (BCG)-unresponsive, high-risk, non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumors who are ineligible for or have elected not to undergo cystectomy\nUsual Adult Dose for Colorectal Cancer:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUses: For the treatment of patients with unresectable or metastatic, microsatellite instability-high (MSI-H) or mismatch repair deficient solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options OR colorectal cancer that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan\nUsual Adult Dose for Solid Tumors:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUses: For the treatment of patients with unresectable or metastatic, microsatellite instability-high (MSI-H) or mismatch repair deficient solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options OR colorectal cancer that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan\nUsual Adult Dose for Gastric Cancer:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For patients with recurrent locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma whose tumors express PD-L1 Positive Score (CPS) 1 or greater as determined by an FDA-approved test, with disease progression on or after 2 or more prior lines of therapy including fluoropyrimidine-and platinum-containing chemotherapy and if appropriate, HER2/neu-targeted therapy\nUsual Adult Dose for Cervical Cancer:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy whose tumors express PD-L1 (CPS 1 or greater) as determined by an FDA-approved test\nUsual Adult Dose for Lymphoma:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of patients with refractory primary mediastinal large B-cell lymphoma (PMBCL) or who have relapsed after 2 or more prior lines of therapy (not recommended for treatment of patients with PMBCL who require urgent cytoreductive therapy)\nUsual Adult Dose for Hepatocellular Carcinoma:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib\nUsual Adult Dose for Merkel Cell Carcinoma:\n200 mg IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of patients with recurrent locally advanced or metastatic Merkel cell carcinoma (MCC)\nUsual Adult Dose for Renal Cell Carcinoma:\n200 mg IV over 30 minutes every 3 weeks in combination with 5 mg axitinib orally 2 times a day until disease progression, unacceptable toxicity, or for pembrolizumab up to 24 months in patients without disease progression\nComments:\n-When axitinib is used in combination with this drug, dose escalation of axitinib above the initial 5 mg dose may be considered at intervals of 6 weeks or longer.\n-See the prescribing information for recommended axitinib dosing information.\nUse: In combination with axitinib for the first-line treatment of advanced renal cell carcinoma (RCC)\nUsual Adult Dose for Esophageal Carcinoma:\n200 mg IV over 30 minutes every 3 weeks in combination until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For patients with recurrent locally advanced or metastatic squamous cell carcinoma of the esophagus whose tumors express PD-L1 (CPS 10 or greater) as determined by an FDA-approved test, with disease progression after one or more prior lines of systemic therapy\nUsual Adult Dose for Endometrial Carcinoma:\n200 mg IV over 30 minutes every 3 weeks in combination with lenvatinib 20 mg orally once daily until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nComments:\n-Refer to the lenvatinib prescribing information for recommended dosing.\nUse: In combination with lenvatinib for the treatment of patients with advanced endometrial carcinoma that is not MSI-H or dMMR, who have disease progression following prior systemic therapy, and are not candidates for curative surgery or radiation\nUsual Pediatric Dose for Hodgkin\'s Disease:\n2 years and older:\n2 mg/kg (up to a maximum of 200 mg) IV 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of pediatric patients 2 years and older with refractory classical Hodgkin lymphoma (cHL), or who have relapsed after 3 or more prior lines of therapy\nUsual Pediatric Dose for Colorectal Cancer:\n2 years and older:\n2 mg/kg (up to a maximum of 200 mg) IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUses: For the treatment of pediatric patients with unresectable or metastatic, microsatellite instability-high (MSI-H) or mismatch repair deficient solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options OR colorectal cancer that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan\nUsual Pediatric Dose for Solid Tumors:\n2 years and older:\n2 mg/kg (up to a maximum of 200 mg) IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUses: For the treatment of pediatric patients with unresectable or metastatic, microsatellite instability-high (MSI-H) or mismatch repair deficient solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options OR colorectal cancer that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan\nUsual Pediatric Dose for Lymphoma:\n2 years and older:\n2 mg/kg (up to a maximum of 200 mg) IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of pediatric patients 2 years and older with refractory primary mediastinal large B-cell lymphoma (PMBCL) or who have relapsed after 2 or more prior lines of therapy (not recommended for treatment of patients with PMBCL who require urgent cytoreductive therapy)\nUsual Pediatric Dose for Merkel Cell Carcinoma:\n2 years and older:\n2 mg/kg (up to a maximum of 200 mg) IV over 30 minutes every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months in patients without disease progression\nUse: For the treatment of patients with recurrent locally advanced or metastatic Merkel cell carcinoma (MCC)\n Detailed Keytruda dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Keytruda injection.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with Keytruda, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Keytruda drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Keytruda: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nSome side effects may occur during the injection. Tell your caregiver if you feel dizzy, light-headed, itchy, hot, sweaty, chilled, or have trouble breathing.\nPembrolizumab affects your immune system, and can cause side effects in many different parts of your body. Some side effects may need to be treated with other medicine.\nCall your doctor at once if you have:\nsores in your mouth, throat, or nose, or on your genital area;\neye pain or vision problems;\nnumbness, tingling, burning pain, redness, rash, or blisters on your hands or feet;\nsevere muscle weakness, severe or ongoing muscle or joint pain;\nfever, swollen glands, neck stiffness;\ndiarrhea or increased stools, severe stomach pain, bloody or tarry stools;\na change in the amount or color of your urine;\nliver problems - loss of appetite, right-sided stomach pain, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes);\nlow levels of sodium in the body - confusion, slurred speech, severe weakness, loss of coordination, feeling unsteady; or\nsigns of a hormonal disorder - frequent or unusual headaches, feeling light-headed, rapid heartbeats, hoarse or deepened voice, increased hunger or thirst, increased urination, constipation, hair loss, muscle pain, sweating, feeling cold, weight changes.\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon Keytruda side effects (some are more likely with combination chemotherapy) may include:\nnausea, vomiting, stomach pain, loss of appetite, diarrhea, constipation;\nlow sodium levels, abnormal liver function or thyroid function tests;\nfever, feeling weak or tired;\ncough, hoarse voice, feeling short of breath;\nitching, rash, or hair loss;\nincreased blood pressure;\npain in your muscles, bones, or joints; or\nsoreness in or around your mouth, nose, eyes, throat, or vagina.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Keytruda side effects (more detail)\n','Keytruda (pembrolizumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.\nKeytruda is used alone or in combination with other medicines to treat certain types of cancer such as:\nskin cancer (melanoma or Merkel cell carcinoma);\nlung cancer;\nhead and neck cancer;\nclassical Hodgkin lymphoma;\nprimary mediastinal large B-cell lymphoma;\ncancer of the kidney, bladder, and urinary tract;\nliver cancer;\ncancer of the cervix or uterus;\nadvanced stomach cancer or esophageal cancer; or\na type of cancer that laboratory testing proves to have certain specific DNA mutations, including colorectal cancer.\nKeytruda is often given when the cancer has spread to other parts of the body, or cannot be treated with surgery or radiation, or when other cancer treatments did not work or have stopped working.\nFor some types of cancer, pembrolizumab is given only if your tumor tests positive for \"PD-L1\", or if the tumor has been tested for a specific genetic marker (including \"EGFR,\" \"ALK,\" \"HER2/neu,\" or \"TMB\").\n','Keytruda can change the way your immune system works, which may cause certain side effects that can lead to serious medical problems.\nKeytruda can cause side effects in many different parts of your body. Some side effects may need to be treated with other medicine, and your cancer treatments may be delayed. You will need frequent medical tests to help your doctor determine if it is safe for you to keep receiving Keytruda.\nCall your doctor at once if you have: skin problems, vision problems, fever, swollen glands, neck stiffness, chest pain, cough, shortness of breath, muscle or joint pain, pale skin, weakness, diarrhea, severe stomach pain, blood in your stools, bruising or bleeding, dark urine, yellowing of the skin or eyes, a hormonal disorder (frequent headaches, feeling light-headed, rapid heartbeats, a deeper voice, increased thirst or urination, feeling cold, weight gain or loss), or a change in the amount or color of your urine.\nBefore taking this medicine\nTell your doctor if you have ever had:\nlung disease or a breathing disorder;\nliver disease;\ndiabetes, or a thyroid disorder;\nan adrenal gland disorder;\nan autoimmune disorder such as lupus, Crohn\'s disease, or ulcerative colitis; or\nan organ transplant or stem cell transplant.\nYou may need to have a negative pregnancy test before starting this treatment. Do not use Keytruda if you are pregnant. Pembrolizumab could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 4 months after your last dose. Tell your doctor right away if you become pregnant.\nDo not breastfeed while using pembrolizumab, and for at least 4 months after your last dose.\nHow is Keytruda given?\nKeytruda is given as an infusion into a vein, usually once every 3 weeks or every 6 weeks. A healthcare provider will give you this injection.\nYour doctor will perform a blood test to make sure Keytruda is the right treatment for your condition.\nThis medicine must be given slowly, and the infusion can take at least 30 minutes to complete.\nYou will need frequent medical tests to help your doctor determine if it is safe for you to keep receiving Keytruda. Do not miss any follow-up visits.\n','Pembrolizumab can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient\'s body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.\n'),(471,'kineret','Usual Adult Dose of Kineret for Rheumatoid Arthritis:\n100 mg subcutaneously once daily at approximately the same time each day\nComments:\n-Alternating the injection site is recommended to avoid discomfort at the site of injection.\nUse: To reduce symptoms and slow the progression of structural damage in moderately to severely active rheumatoid arthritis (RA) in patients who have failed 1 or more disease modifying antirheumatic drugs (DMARDs)\nUsual Adult Dose of Kineret for Interleukin-1 Receptor Antagonist Deficiency:\nInitial dose: 1 to 2 mg/kg subcutaneously daily\nDose escalation: Adjust doses in 0.5 to 1 mg/kg increments\nMaximum dose: 8 mg/kg subcutaneously daily\nUse: For the treatment of Deficiency of Interleukin-1 Receptor Antagonist (DIRA)\nUsual Pediatric Dose of Kineret for Cryopyrin-Associated Periodic Syndrome:\nInitial dose: 1 to 2 mg/kg subcutaneously daily\nDose escalation: Adjust doses in 0.5 to 1 mg/kg increments\nMaximum dose: 8 mg/kg subcutaneously daily\nNOTE: Once daily administration is generally recommended, but the dose may be split into twice daily administrations.\nComments:\n-The therapeutic response is primarily reflected by reduction in symptoms such as fever, rash, joint pain, and headache, but also in inflammatory serum markers (CRP/SAA levels), or occurrence of flares.\nUse: Cryopyrin-Associated Periodic Syndromes (CAPS): Treatment of Neonatal-Onset Multisystem Inflammatory Disease (NOMID)\nUsual Pediatric Dose of Kineret for Interleukin-1 Receptor Antagonist Deficiency:\n1 month and older:\nInitial dose: 1 to 2 mg/kg subcutaneously daily\nDose escalation: Adjust doses in 0.5 to 1 mg/kg increments\nMaximum dose: 8 mg/kg subcutaneously daily\nUse: For the treatment of Deficiency of Interleukin-1 Receptor Antagonist (DIRA) in children 1 month and older\n Detailed Kineret dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','You may have a higher risk of infection from Kineret if you are also using:\ncertolizumab;\netanercept;\ngolimumab;\ninfliximab;\nadalimumab; or\ncancer medicines, steroids, or medicines to prevent organ transplant rejection.\nThis list is not complete. Other drugs may interact with anakinra, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Kineret drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kineret: hives, sweating, severe itching; wheezing, difficult breathing; fast or pounding heartbeats; dizziness, fainting; swelling of your face, lips, tongue, or throat.\nIf you are using Kineret for DIRA, you may have an increased risk of allergic reactions, especially in the first weeks of treatment.\nCall your doctor at once if you have:\nfever or chills;\nopen sores on your body; or\nsigns of tuberculosis: fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired.\nCommon Kineret side effects may include:\nworsening arthritis symptoms;\nnausea, vomiting, diarrhea, stomach pain;\nheadache;\njoint pain;\nflu symptoms;\ncold symptoms such as stuffy nose, sneezing, sore throat; or\nredness, bruising, itching, stinging, or swelling where the injection was given.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kineret side effects (more detail)\n','Kineret (anakinra) reduces the actions of chemicals in the body that are involved in inflammatory and immune responses.\nKineret is used to treat the symptoms of moderate to severe rheumatoid arthritis in adults. Kineret may also help slow the progress of the disease. This medicine is usually given after other arthritis medications did not work or have stopped working.\nKineret is also used in newborn babies to treat a rare genetic condition called neonatal onset multisystem inflammatory disease (NOMID). NOMID is a form of cryopyrin-associated periodic syndromes (CAPS). This condition causes uncontrolled inflammation in many parts of the body, including the skin, joints, and central nervous system.\nKineret is also used to control symptoms of a condition called Deficiency of Interleukin-1 Receptor Antagonist (DIRA) in adults and children. DIRA is a very rare genetic condition that causes a severe inflammatory reaction during the first days of life and can lead to organ failure throughout the body.\n','You should not use Kineret if you are allergic to medicines that contain E. coli bacteria proteins, or if you have an active infection.\nBefore using Kineret, tell your doctor if you have asthma, kidney disease, a latex allergy, a weak immune system, an active or chronic infection, or signs of infection such as fever, chills, or open sores on your skin.\nKineret can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Stop using this medicine and call your doctor right away if you have signs of infection such as: fever, chills, flu symptoms, mouth sores, weight loss, or feeling tired or short of breath.\nYou may have a higher risk of infection if you are also using adalimumab (Humira), certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), adalimumab (Humira), cancer medicines, steroids, or medicines to prevent organ transplant rejection.\nDo not give Kineret to anyone under 18 years old without medical advic\nBefore taking this medicine\nYou should not use Kineret if you are allergic to anakinra or if you have:\nan active infection; or\nan allergy to any medicine that contains E. coli bacteria proteins.\nTo make sure Kineret is safe for you, tell your doctor if you have:\nkidney disease;\nan active or chronic infection;\nfever, chills, or open sores on your skin;\na weak immune system (caused by disease or by using certain medicines):\nasthma; or\ntuberculosis.\nTell your doctor if you are pregnant or plan to become pregnant. Having rheumatoid arthritis or CAPS during pregnancy may increase the risk of premature birth or low birth weight. The benefit of treating rheumatoid arthritis or CAPS may outweigh any risks to the baby.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nDo not give this medicine to a child without medical advice. Kineret is not approved to treat rheumatoid arthritis in anyone younger than 18 years old.\nHow should I use Kineret?\nUse Kineret exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nKineret is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.\nKineret is given either once per day or once every other day. Follow your doctor\'s dosing instructions very carefully. Inject your dose at the same time of day when you use the medicine.\nYour healthcare provider will show you where on your body to inject Kineret. Use a different place each time you give an injection. Each injection should be given at least 1 inch away from where you last injected the medicine.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nDo not shake the prefilled syringe or you may ruin the medicine.\nPrepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.\nCall your doctor if your arthritis symptoms do not improve, or if they get worse while using Kineret.\nAnakinra affects your immune system. You may get infections more easily. You will need frequent medical tests while using Kineret and for several months after you stop using it.\nStore in the refrigerator, do not freeze. Protect from light. Throw away any unused medicine after the expiration date on the label has passed.\nEach prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n','Do not receive a \"live\" vaccine while using Kineret, or you could develop an infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\nAvoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\n'),(472,'kisqali','Usual Adult Dose for Breast Cancer:\n600 mg orally once a day for 21 consecutive days followed by 7 days off for a complete cycle of 28 days; continue until disease progression or unacceptable toxicity\nComments:\n-Refer to the manufacturer product information for dosing and administration recommendations for the co-administered aromatase inhibitor (e.g., letrozole).\n-When given with this drug, the recommended dose of fulvestrant is 500 mg administered on Days 1, 15, 29, and once monthly thereafter. Refer to the full prescribing information of fulvestrant.\n-Pre/perimenopausal women treated with the combination of this drug plus an aromatase inhibitor or fulvestrant should be treated with a luteinizing hormone-releasing hormone (LHRH) agonist according to current clinical practice standards.\nUses:\n-In combination with an aromatase inhibitor as initial endocrine-based therapy for the treatment of postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.\n-In combination with fulvestrant for the treatment of postmenopausal women with HR-positive, HER2-negative advanced or metastatic breast cancer, as initial endocrine based therapy or following disease progression on endocrine therapy.\n Detailed Kisqali dosage information\nWhat happens if I miss a dose?\nSkip the missed dose. Take your next dose at the regular time and stay on your once-daily schedule. Do not use 2 doses in one day.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nRibociclib can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\nMany drugs can interact with ribociclib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Kisqali drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kisqali: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nSeek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nlow white blood cell counts - fever, mouth sores, skin sores, sore throat, cough, trouble breathing;\nsigns of inflammation in the lungs - new or worsening cough, painful or difficult breathing, wheezing, feeling short of breath even while resting; or\nliver problems - loss of appetite, upper stomach pain, tiredness, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes).\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon Kisqali side effects may include:\nlow white blood cells, infections;\ncough;\nnausea, vomiting;\ndiarrhea, constipation;\nfeeling tired;\nrash;\nheadache; or\nhair loss.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kisqali side effects (more detail)\n','Kisqali (ribociclib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.\nKisqali is used to treat hormone-related breast cancer in women. Ribociclib is used only if your cancer tests negative for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.\nKisqali is used when the cancer has progressed or has spread to other parts of the body after other treatments.\nKisqali is given in combination with another cancer medicine such as letrozole (Femara) or fulvestrant (Faslodex).\n','Kisqali can cause serious side effects on your heart, liver, or lungs. Call your doctor at once if you have chest pain, fast or pounding heartbeats, trouble breathing, cough (with or without mucus), sudden dizziness, right-sided upper stomach pain, loss of appetite, unusual bleeding or bruising, dark urine, or yellowing of your skin or eyes.\nYou will need frequent medical tests while taking Kisqali. Your cancer treatments may be delayed based on the results of these tests. Tell your doctor if you have signs of infection, such as fever or chills.\nBefore taking this medicine\nYou should not use Kisqali if you are allergic to ribociclib, or if you also take tamoxifen.\nYour doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Kisqali.\nTo make sure Kisqali is safe for you, tell your doctor if you have ever had:\nslow heartbeats;\nheart disease or prior heart attack;\nlong QT syndrome;\nan electrolyte imbalance (such as low levels of calcium, magnesium, phosphorus, or potassium in your blood);\nliver disease;\nkidney disease; or\nsigns of infection (fever, chills).\nTell your doctor whether or not you have gone through menopause.\nYou may need to have a negative pregnancy test before starting this treatment.\nDo not use Kisqali if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.\nThis medicine may affect fertility (ability to have children) in men. Talk with your doctor if you have concerns about this risk.\nYou should not breastfeed while using Kisqali and for at least 3 weeks after your last dose.\nHow should I take Kisqali?\nTake Kisqali exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nKisqali is given in a 28-day treatment cycle. You will take the medicine for the first 21 days of each cycle, followed by 7 days off. Your doctor will determine how long to treat you with Kisqali.\nSwallow the tablet whole and do not crush, chew, or break it.\nTake the medicine at the same time each morning, with or without food.\nIf you vomit after taking the medicine, wait until the next day to take your next dose.\nDo not use a broken or damaged pill.\nYou may need frequent medical tests to be sure Kisqali is not causing harmful effects. Your cancer treatments may be delayed based on the results.\nStore in the original container at room temperature, away from moisture and heat.\n','Grapefruit may interact with ribociclib and lead to unwanted side effects. Avoid the use of grapefruit products.\nAvoid taking an herbal supplement containing St. John\'s wort at the same time you are taking Kisqali.\n'),(473,'klonopin','Take Klonopin exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Never use clonazepam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.\nNever share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nYou will need frequent medical tests.\nDo not stop using Klonopin suddenly, even if you feel fine. Stopping suddenly may cause increased seizures or unpleasant withdrawal symptoms. Follow your doctor\'s instructions about tapering your dose.\nSwallow the regular tablet whole, with a full glass of water.\nClonazepam doses are based on weight in children. Your child\'s dose needs may change if the child gains or loses weight.\nRemove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.\nYour doctor will need to check your progress on a regular basis.\nCall your doctor if this medicine seems to stop working as well in treating your seizures or panic attacks.\nSeizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor\'s advice.\nStore at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.\n Detailed Klonopin dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include extreme drowsiness, confusion, muscle weakness, or coma.\n','Taking Klonopin with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your other medicines, especially:\nphenytoin;\nvalproic acid;\nThis list is not complete. Other drugs may interact with clonazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Klonopin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Klonopin : hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nClonazepam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. A person caring for you should seek emergency medical attention if you have weak or shallow breathing, if you are hard to wake up, or if you stop breathing.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nnew or worsening seizures;\nsevere drowsiness;\nweak or shallow breathing;\nunusual changes in mood or behavior;\nnightmares, hallucinations;\nthoughts of suicide or hurting yourself;\nunusual or involuntary eye movements.\nThe sedative effects of clonazepam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Klonopin.\nCommon Klonopin side effects may include:\ndrowsiness, dizziness;\nfeeling tired or depressed;\nmemory problems; or\nproblems with walking or coordination.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Klonopin side effects (more detail)\n','Klonopin (clonazepam) is a benzodiazepine. It is thought that clonazepam works by enhancing the activity of certain neurotransmitters in the brain. Clonazepam is also a seizure medicine, also called an anti-epileptic drug.\nKlonopin is used to treat certain seizure disorders (including absence seizures or Lennox-Gastaut syndrome in adults and children.\nKlonopin is also used to treat panic disorder (including agoraphobia) in adults.\n','You should not use Klonopin if you have narrow-angle glaucoma, severe liver disease, or if you are allergic to Valium or a similar medicine.\nCall your doctor if you have any new or worsening symptoms of depression, unusual changes in behavior, or thoughts about suicide or hurting yourself.\nDo not drink alcohol while taking this medicine. Clonazepam may be habit-forming. Never share Klonopin with another person. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.\nUsing Klonopin with opiate medications can result in sedation, respiratory depression, coma, and death.\nBefore taking this medicine\nYou should not take Klonopin if you have:\nnarrow-angle glaucoma;\nsevere liver disease; or\na history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Restoril, Tranxene, Valium, Versed, Xanax, and others).\nTo make sure Klonopin is safe for you, tell your doctor if you have ever had:\nkidney or liver disease;\nbreathing problems;\ndepression, mood problems, or suicidal thoughts or behavior; or\nporphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).\nSome people have thoughts about suicide when taking seizure medication. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nIf you use clonazepam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.\nDo not start or stop taking seizure medication during pregnancy without your doctor\'s advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of clonazepam on the baby.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nDo not give this medicine to a child without medical advice. Klonopin is not approved to treat panic disorder in anyone younger than 18 years old.\n','Do not drink alcohol. Dangerous side effects or death could occur.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\n'),(474,'klor-con','Take Klor-Con exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nTake Klor-Con with food if the medicine upsets your stomach.\nAlways follow directions on the medicine label about giving this medicine to a child.\nTake the tablet or capsule with a full glass of water.\nDo not crush, chew, or suck on a potassium tablet or capsule. Sucking on the pill could irritate your mouth or throat.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Mix the oral solution with least 4 ounces of water before taking it.\nYou may need to follow a special diet while using Klor-Con. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.\nCall your doctor if you have trouble swallowing a Klor-Con capsule or tablet. You may be able to dissolve the tablet in water, or mix the medicine from a capsule with soft food. Carefully follow your doctor\'s instructions.\nYou may need frequent medical tests. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.\nSome tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.\nStore at room temperature away from moisture, heat, and light. Keep the medication in a closed container.\n Detailed Klor-Con dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include stomach pain, vomiting, irregular heartbeats, chest pain, muscle weakness, loss of movement, numbness or tingling, or feeling light-headed.\n','Tell your doctor about all your other medicines, especially:\nmedicine to prevent organ transplant rejection;\na diuretic or \"water pill\"; or\nheart or blood pressure medication.\nThis list is not complete. Other drugs may interact with potassium chloride, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Klor-Con drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Klor-Con: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using Klor-Con and call your doctor at once if you have:\nsevere throat irritation;\nchest pain, trouble breathing;\nstomach bloating, severe vomiting, severe stomach pain;\nhigh potassium level - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nCommon Klor-Con side effects may include:\nnausea, vomiting, diarrhea;\ngas, stomach pain; or\nthe appearance of a Klor-Con tablet in your stool.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Klor-Con side effects (more detail)\n','Klor-Con contains potassium chloride, a mineral that is found in many foods and is needed for several functions of your body, especially the beating of your heart.\nKlor-Con is used to prevent or to treat low blood levels of potassium (hypokalemia). Potassium levels can be low as a result of a disease or from taking certain medicines, or after a prolonged illness with diarrhea or vomiting.\nKlor-Con is available as effervescent tablets, extended release tablets, extended release capsules (sprinkle), and powder for oral solution.\n','You should not use Klor-Con if you have high levels of potassium in your blood (hyperkalemia), or if you also take a \"potassium-sparing\" diuretic.\nTo be sure Klor-Con is helping your condition, your blood may need to be tested often. Your heart rate and rhythm may also be checked using an electrocardiograph or ECG (sometimes called an EKG) to measure electrical activity of the heart. Do not miss any scheduled appointments.\nSerious side effects of potassium include uneven heartbeat, muscle weakness or limp feeling, severe stomach pain, and numbness or tingling in your hands, feet, or mouth.\nDo not stop taking Klor-Con without first talking to your doctor. If you stop taking potassium suddenly, your condition may become worse.\nDo not crush, chew, break, or suck on an extended-release tablet or capsule. Swallow the pill whole. Breaking or crushing the pill may cause too much of the drug to be released at one time. Sucking on a potassium tablet can irritate your mouth or throat. Take Klor-Con with food or just after a meal.\nBefore taking this medicine\nYou should not use Klor-Con if you are allergic to potassium chloride, or if:\nyou have high levels of potassium in your blood (hyperkalemia); or\nyou take a \"potassium-sparing\" diuretic (water pill) such as amiloride, spironolactone, or triamterene.\nTo make sure Klor-Con is safe for you, tell your doctor if you have ever had:\nheart problems;\nhigh blood pressure;\nliver or kidney disease;\na large tissue injury such as a severe burn;\nan electrolyte imbalance (such as low levels of calcium or magnesium in your blood);\ntrouble swallowing;\nslow digestion;\nstomach bleeding, an ulcer, or a blockage in your stomach or intestines;\nan adrenal gland disorder;\ndiabetes; or\nsevere dehydration.\nTell your doctor if you are pregnant or breastfeeding.\n','Do not use potassium supplements or other products that contain potassium, unless your doctor has told you to. Salt substitutes or low-salt foods often contain potassium. Read the label of any food or medicine to see if it contains potassium.\n'),(475,'kombiglyze-xr','Usual Adult Dose of Kombiglyze XR for Diabetes Type 2:\nIndividualize dose based patient\'s current regimen, effectiveness, and tolerability; gradual dose titration of metformin is advised to reduce gastrointestinal side effects.\nSaxagliptin-Metformin XR:\nUsual dose: 1 tablet orally once a day with the evening meal\nMaximum dose: saxagliptin 5 mg-metformin 2000 mg orally once a day\nMaximum dose with concomitant strong CYP450 3A4/5 inhibitors: saxagliptin 2.5-metformin 1000 mg orally once a day\n-Patients not currently treated with metformin: Initial dose saxagliptin 5 mg-metformin 500 mg orally once daily\n-Patients currently treated with metformin: Initial dose: saxagliptin 5 mg plus the dose of metformin that is already being taken, or the nearest therapeutically appropriate dose.\nComments:\n-Patients requiring saxagliptin 2.5 mg per day AND are either metformin-naive or require a dose of metformin greater than 1000 mg per day should use the individual components.\n-Following a switch from metformin immediate-release to metformin extended release, glycemic control should be closely monitored and dosage adjustments made according.\n-When used in combination with a sulfonylurea or insulin, a lower dose of the sulfonylurea or insulin may be considered to reduce the risk of hypoglycemia.\n-Note: There are saxagliptin-metformin combination products available internationally that contain immediate-release metformin; saxagliptin-metformin products containing immediate-release metformin should be dosed twice a day.\nUse: An adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes when treatment with both saxagliptin and metformin is appropriate.\n Detailed Kombiglyze XR dosage information\nWhat happens if I miss a dose?\nTake the medicine (with food) as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure).\n','Many drugs can interact with metformin and saxagliptin, making this medicine less effective or increasing your risk of lactic acidosis.\nTell your doctor about all your other medicines, especially:\nan antibiotic or antifungal medicine;\ninsulin or oral diabetes medicine; or\nmedicine to treat HIV or AIDS.\nThis list is not complete. Other drugs may interact with metformin and saxagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Kombiglyze XR drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kombiglyze XR: hives, itching, peeling skin; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop taking this medicine and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.\nSome people using metformin develop lactic acidosis, which can be fatal. Get emergency medical help if you have even mild symptoms such as:\nunusual muscle pain;\nfeeling cold;\ntrouble breathing;\nfeeling dizzy, light-headed, tired, or very weak;\nstomach pain, vomiting; or\nirregular heart rate.\nCall your doctor at once if you have any of these serious side effects:\nsevere autoimmune reaction - itching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints;\npain or burning when you urinate; or\nsymptoms of heart failure - shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nCommon Kombiglyze XR side effects may include:\ndiarrhea, nausea;\nheadache; or\ncold symptoms such as runny or stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kombiglyze XR side effects (more detail)\n','Kombiglyze XR contains a combination of metformin and saxagliptin. Metformin and saxagliptin are oral diabetes medicines that help control blood sugar levels.\nMetformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Saxagliptin works by regulating the levels of insulin your body produces after eating.\nKombiglyze XR is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.\nKombiglyze XR is not for treating type 1 diabetes.\n','You should not use Kombiglyze XR if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).\nYou may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.\nBefore taking this medicine\nYou should not use Kombiglyze XR if you are allergic to metformin or saxagliptin (Onglyza), or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).\nTell your doctor if you have ever had:\nkidney disease (your kidney function may need to be checked before you take Kombiglyze XR);\nliver disease;\nheart disease;\npancreatitis;\nhigh triglycerides (a type of fat in the blood);\ngallstones; or\nalcoholism.\nYou may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.\nIf you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Kombiglyze XR. Be sure your caregivers know ahead of time that you are using this medication.\nFollow your doctor\'s instructions about using Kombiglyze XR if you are pregnant or breastfeeding a baby. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Your dose needs may also be different while you are breastfeeding.\nMetformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.\nKombiglyze XR is not approved for use by anyone younger than 18 years old.\nHow should I take Kombiglyze XR?\nTake Kombiglyze XR exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake Kombiglyze XR with food.\nSwallow the tablet whole and do not crush, chew, or break it.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nKombiglyze XR is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore Kombiglyze XR at room temperature away from moisture and heat.\n','Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.\n'),(476,'krill-oil',NULL,'\nEstrogens (birth control pills or hormone replacement)\nA blood thinner such as warfarin (Coumadin, Jantoven)\nAspirin or NSAIDS (naproxen, ibuprofen, Aleve, Motrin IB, Advil)\nA beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others, or\nA diuretic (water pill) such as chlorothiazide (Diuril), hydrochlorothiazide (HydroDIURIL, Microzide), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn), and others\nOrlistat (Xenical, Alli) for weight loss\nThis list is not complete and other drugs may interact with Fish Oil. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.1\n','\nFever, chills, body aches, flu symptoms\nChest pain\nUneven heartbeats\nBack pain\nMild skin rash\nFishy aftertaste or belching in some patients\n1\n','Krill (Euphausia superba) is a small crustacean with an appearance similar to shrimp. They are found in the colder waters of the ocean. Krill primarily serve as a food source for other animals in the ocean, for example - whales, seals, penguins, squid and fish.\nKrill is found in the oceans off of Antarctica, Canada, and Japan. Harvesting of krill is controversial. There is concern that commercial harvesting of Krill for use in Krill Oil supplements could threaten the species that consume it for food, including whales. All krill oil sold in nutritional supplements is harvested out of the open ocean, upsetting the natural balance of food supplies for larger marine animals.\nCommercial uses of Krill include salmon aquaculture farming, harvesting for use in Krill Oil capsules, as food for home aquariums, and as a human food source. Krill, known as Okiami has been harvested by the Japanese as a human food source since the 19th century, and is also consumed in South Korea and Taiwan. Krill has a pink or red appearance due to the plankton that they consume as a food source in the ocean.1\nWhat is in Krill Oil?\nKrill contains an oil that is similar to the oils found in fish oils, the omega-3 fatty acids. Omega-3 fatty acids are recommended for use in lowering triglyceride levels. Krill Oil use as a supplement to lower blood lipids is increasing in popularity.1\nKrill Oil contains:\nThe omega-3 polyunsaturated fatty acids EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic). Omega-3 polyunsaturated fatty acids are also found in oils from certain types of fish, vegetables, and other plant sources.\nUnlike fish oil, the omega-3 fatty acids in Krill oil are absorbed and carried to the body\'s cells in phospholipid form. Omega-3 fatty acids, in combination with diet and exercise, work by lowering the body\'s production of “bad”, low density lipoprotein (LDL) and triglycerides, and may raise high density lipoprotein (HDL) “good”  cholesterol. High levels of cholesterol and triglycerides can lead to coronary artery disease, heart disease, and stroke.\nSupportive, but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.\nKrill Oil also contains:\nPhospholipid-derived fatty acids (PLFA), which may result in better absorption, and marine lethicin2\nA carotenoid antioxidant called astaxanthin. Antioxidants inhibit oxidation and may neutralize the oxidant effect of free radicals and other substances in body tissues that may lead to disease.\nKrill Oil has also been used to treat high blood pressure, stroke, cancer, osteoarthritis, depression and premenstrual syndrome (PMS), although high quality studies with adequately sized populations validating these uses are lacking. Patients should speak with their physician prior to using Krill Oil for any condition.\nWarnings issued by the FDA note that certain fish (marlin, tuna, swordfish) may contain toxins such as methylmercury, leading some consumers to be wary of eating fish to obtain omega-3 fatty acids. Manufacturers of Krill Oil suggest it may be safer due to lower levels of contaminants such as mercury. The FDA has issued recommendations that women who are pregnant or planning to become pregnant, and young children avoid eating more than 6 ounces of fish per week. However, Krill may also contain methylmercury and other pollutants from sea water, although they are lower on the food chain and may contain lower values of such pollutants. One study noted that Krill harvested from Antarctica contains high levels of organic pesticides.3\nManufacturers of Krill Oil claim one of the advantages of Krill Oil over Fish Oil is that it does not lead to the fishy aftertaste, reflux or belching of fish flavors, a common side effect with fish oil supplements. However, Krill Oil may still lead to these side effects in some patients.\nThe U.S. Food and Drug Administration (FDA) has not specifically made recommendations on Krill Oil safety or effectiveness. Krill Oil is considered a dietary supplement and does not require a prescription.1,4,5,6,7,8\nKrill Oil may also be used for purposes not listed in this medication guide.\n','Take Krill Oil exactly as directed on the label, or as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended.\nKrill Oil should not be used in patients with a fish or shrimp allergy, or probably any other type of seafood. Tests for susceptibility to allergic reactions to Krill Oil have not been completed.\nPeople with coagulopathy or taking anticoagulants or other medications should notify their physician prior to taking dietary supplements.\nStop taking Krill Oil at least two weeks prior to any scheduled surgery or procedure.\nSwallow the Krill Oil capsule whole. Do not puncture or open the capsule.\nMarine Oils, such as Krill Oil,  is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.1\nThere may be other drugs that can interact with Krill Oil. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\nStop using Krill Oil and get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nLess serious side effects are more likely, and you may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.\nBefore Taking Krill Oil\nDiabetes\nLiver disease\nA pancreas disorder\nBlood clotting disorder or risk of stroke\nUpcoming surgery or procedure that might increase your risk for bleeding\nUnderactive thyroid\nIf you drink more than two alcoholic beverages per day\nLovaza\n1\nFish Oil and Pregnancy and Breastfeeding Warnings\n','\n'),(477,'kristalose','Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.\nMeasure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.\nThe liquid form of lactulose may become slightly darker in color, but this is a harmless effect. However, do not use the medicine if it becomes very dark, or if it gets thicker or thinner in texture.\nKristalose powder should be mixed with at least 4 ounces of water. You may also use fruit juice or milk to make the medication taste better.\nIt may take up to 48 hours before you have a bowel movement after taking Kristalose.\nIf you use Kristalose over a long period of time, your doctor may want you to have occasional blood tests. Do not miss any scheduled appointments.\nStore Kristalose at room temperature away from moisture and heat.\n Detailed Kristalose dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, and muscle weakness or limp feeling.\n','There may be other drugs that can interact with Kristalose. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\n Kristalose drug interactions (more detail)\nDoes Kristalose interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using Kristalose and call your doctor at once if you have severe or ongoing diarrhea.\nLess serious side effects may include:\nbloating, gas;\nstomach pain;\ndiarrhea; or\nnausea, vomiting.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kristalose side effects (more detail)\n','Kristalose is a type of sugar. It is broken down in the large intestine into mild acids that draw water into the colon, which helps soften the stools.\nKristalose is used to treat chronic constipation.\nKristalose is sometimes used to treat or prevent certain conditions of the brain that are caused by liver failure, which can lead to confusion, problems with memory or thinking, behavior changes, tremors, feeling irritable, sleep problems, loss of coordination, and loss of consciousness.\nKristalose may also be used for purposes not listed in this medication guide.\n','You should not use this medication if you are on a special diet low in galactose (milk sugar).\nBefore taking Kristalose, tell your doctor if you have diabetes or if you need to have any type of intestinal test using a scope (such as a colonoscopy).\nIt may take up to 48 hours before you have a bowel movement after taking Kristalose.\nStop using Kristalose and call your doctor at once if you have severe or ongoing diarrhea.\nThe liquid form of lactulose may become slightly darker in color, but this is a harmless effect. However, do not use the medicine if it becomes very dark, or if it gets thicker or thinner in texture.\nIf you use Kristalose over a long period of time, your doctor may want you to have occasional blood tests. Do not miss any scheduled appointments.\nBefore taking this medicine\nYou should not use this medication if you are on a special diet low in galactose (milk sugar).\nTo make sure you can safely take Kristalose, tell your doctor if you have other medical conditions, especially:\ndiabetes; or\nif you need to have any type of intestinal test using a scope (such as a colonoscopy).\nFDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.\nIt is not known whether lactulose passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.\n','Avoid using antacids without your doctor\'s advice. Use only the type of antacid your doctor recommends. Some antacids can make it harder for your body to absorb Kristalose.\n'),(478,'kyleena',NULL,'Some drugs can affect your blood levels of levonorgestrel, which could make this form of birth control less effective. Tell your doctor about all your other medicines, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Kyleena drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nGet emergency medical help if you have severe pain in your lower stomach or side. This could be a sign of a tubal pregnancy (a pregnancy that implants in the fallopian tube instead of the uterus). A tubal pregnancy is a medical emergency.\nThe levonorgestrel IUD may become embedded into the wall of the uterus, or may perforate (form a hole) in the uterus. If this occurs, the device may no longer prevent pregnancy, or it may move outside the uterus and cause scarring, infection, or damage to other organs. Your doctor may need to surgically remove the device.\nCall your doctor at once if you have:\nsevere cramps or pelvic pain, pain during sexual intercourse;\nextreme dizziness or light-headed feeling;\nsevere migraine headache;\nheavy or ongoing vaginal bleeding, vaginal sores, vaginal discharge that is watery, foul-smelling discharge, or otherwise unusual;\npale skin, weakness, easy bruising or bleeding, fever, chills, or other signs of infection;\njaundice (yellowing of the skin or eyes); or\nsudden numbness or weakness (especially on one side of the body), confusion, problems with vision, sensitivity to light.\nCommon side effects may include:\npelvic pain, vaginal itching or infection, missed or irregular menstrual periods, changes in bleeding patterns or flow (especially during the first 3 to 6 months);\ntemporary pain, bleeding, or dizziness during insertion of the IUD;\novarian cysts (pelvic pain that disappears within 3 months);\nstomach pain, nausea, vomiting, bloating;\nheadache, migraine, depression, mood changes;\nback pain, breast tenderness or pain;\nweight gain, acne, changes in hair growth, loss of interest in sex; or\npuffiness in your face, hands, ankles, or feet.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kyleena side effects (more detail)\n','Levonorgestrel is a female hormone that can cause changes in your cervix and uterus. Kyleena is a T-shaped plastic intrauterine device (IUD) that is placed in the uterus where it slowly releases the hormone.\nKyleena used to prevent pregnancy for 3 to 6 years. You may use this IUD whether you have children or not. Mirena is also used to treat heavy menstrual bleeding in women who choose to use an intrauterine form of birth control.\nLevonorgestrel is a progestin and does not contain estrogen. Kyleena should not be used as emergency birth control.\nKyleena may also be used for purposes not listed in this medication guide.\n','You should not use this device if you have abnormal vaginal bleeding, a pelvic infection, certain other problems with your uterus or cervix, or if you have breast or uterine cancer, liver disease or liver tumor, or a weak immune system.\nDo not use during pregnancy. Call your doctor if you think you might be pregnant.\n','Avoid having more than one sex partner. The IUD can increase your risk of developing a serious pelvic infection, which is often caused by sexually transmitted disease. Kyleena will not protect you from sexually transmitted diseases, including HIV and AIDS. Using a condom is the only way to help protect yourself from these diseases.\nCall your doctor if your sex partner develops HIV or a sexually transmitted disease, or if you have any change in sexual relationships.\n'),(479,'kymriah','Usual Adult Dose of Kymriah for Acute Lymphoblastic Leukemia:\nUp to Age 25 Years:\n-Body Weight 50 kg or less: 0.2 to 5 x 10(6) chimeric antigen receptor (CAR)-positive viable T cells per kg of body weight.\n-Body Weight Above 50 kg: 0.1 to 2.5 x 10(8) CAR-positive viable T cells\nDuration of Therapy: Infuse this drug 2 to 14 days after completion of lymphodepleting chemotherapy.\nComments:\n-Base the dosage on the patient\'s weight at the time of leukapheresis.\n-Administer this drug via IV infusion within 30 minutes of thawing at 10 to 20 mL per minute (adjusted as appropriate for smaller children and smaller volumes); the infusion bag volume ranges from 10 to 50 mL.\n-Pre-medicate patients with acetaminophen and diphenhydramine or another H1-antihistamine approximately 30 to 60 minutes prior to infusion of this drug; avoid using corticosteroids at any time except in the case of a life-threatening emergency.\nUse: Treatment of patients up to age 25 with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.\nUsual Pediatric Dose for Acute Lymphoblastic Leukemia:\n-Body Weight 50 kg or less: 0.2 to 5 x 10(6) chimeric antigen receptor (CAR)-positive viable T cells per kg of body weight.\n-Body Weight Above 50 kg: 0.1 to 2.5 x 10(8) CAR-positive viable T cells\nDuration of Therapy: Infuse this drug 2 to 14 days after completion of lymphodepleting chemotherapy.\nComments:\n-Base the dosage on the patient\'s weight at the time of leukapheresis.\n-Administer this drug via IV infusion within 30 minutes of thawing at 10 to 20 mL per minute, adjusted as appropriate for smaller children and smaller volumes; the infusion bag volume ranges from 10 to 50 mL.\n-Pre-medicate patients with acetaminophen and diphenhydramine or another H1-antihistamine approximately 30 to 60 minutes prior to infusion of this drug; avoid using corticosteroids at any time except in the case of a life-threatening emergency.\nUse: Treatment of patients up to age 25 with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.\n Detailed Kymriah dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss any of your chemotherapy treatment, or if you miss a dose of your medications to prevent side effects of Kymriah.\nWhat happens if I overdose?\nSince this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.\n','Other drugs may interact with tisagenlecleucel, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Kymriah drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Kymriah: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nA serious side effect of Kymriah is called cytokine release syndrome (CRS). Tell your caregivers right away if you have signs of this condition: fever, chills, trouble breathing, body aches, vomiting, diarrhea, or feeling light-headed. Your caregivers will have medication available to quickly treat CRS if it occurs.\nAlso tell your caregivers or seek emergency medical attention if you have signs of life-threatening nerve problems: problems with speech, problems with thinking or memory, confusion, or a seizure.\nAlso call your doctor at once if you have:\nheadaches, unusual tiredness;\ntremors, anxiety, agitation;\nunusual thoughts or behavior;\ntrouble speaking or understanding what is said to you; or\nsigns of infection - fever, chills, flu symptoms, mouth sores, skin sores, easy bruising or bleeding, cough, trouble breathing.\nCommon Kymriah side effects may include:\nnausea, vomiting, diarrhea, loss of appetite;\nfever;\nheadache, confusion, feeling tired;\nbleeding; or\nfast heartbeats.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Kymriah side effects (more detail)\nBefore taking this medicine\nTo make sure Kymriah is safe for you, tell your doctor if you have ever had:\nhepatitis B or C;\nHIV (human immunodeficiency virus); or\nif you have received a vaccine in the past 2 weeks.\nWomen may need pregnancy testing before receiving this medicine. You may also need to use birth control to prevent pregnancy during and shortly after treatment with Kymriah and chemotherapy.\nIf you receive Kymriah during pregnancy, your baby\'s blood may need to be tested after it is born. This is to evaluate any effects the medicine may have had on the baby.\nIt may not be safe to breastfeed while using Kymriah . Ask your doctor about any risk.\nHow is Kymriah given?\nKymriah is available only at an authorized hospital or clinic, and must be given by specially trained healthcare professionals.\nKymriah is given after a procedure called leukapheresis (LOO-kuh-fuh-REE-sis).\nDuring leukapheresis, some of your blood is collected through a small tube (catheter) placed into a vein. The catheter is connected to a machine that separates your white blood cells from other parts of the blood.\nThe cells are then sent to a laboratory where they are made into tisagenlecleucel. Because it will take time to process your blood cells into tisagenlecleucel, you will not receive the medicine on the same day your blood cells are drawn.\nAbout 2 to 14 days before Kymriah is given, you will be pre-treated with chemotherapy to help prepare your body for tisagenlecleucel.\nJust before you receive Kymriah, you will be given other medications to help prevent serious side effects or allergic reaction.\nOnce your body is ready to receive tisagenlecleucel, your care providers will inject the medicine into a vein through an IV.\nFor at least 4 weeks, plan to stay near the hospital or clinic where you received Kymriah. Avoid being so far away that it takes you longer than 2 hours to travel back to the hospital.\nSerious and sometimes fatal infections may develop after the injection. Call your doctor right away if you have fever, chills, easy bruising, unusual bleeding, or other signs of infection.\nThis medicine can cause you to have a false positive screening test for HIV (human immunodeficiency virus). Tell any doctor who treats you that you are using Kymriah.\nUsing Kymriah may increase your risk of developing other types of cancer, or causing your leukemia to come back. Your doctor will need to check your progress for the rest of your life.\nIf you have ever had hepatitis B, Kymriah can cause this condition to come back or get worse. You will need frequent blood tests to check your liver function during treatment and for several months after you stop using this medicine.\n','Kymriah (tisagenlecleucel) is an immunotherapy medicine used to treat a certain type of acute lymphoblastic leukemia in people who are up to 25 years old.\nKymriah is also used to treat certain adult patients with large B-cell lymphoma.\nKymriah is given after other treatments have failed.\nKymriah is made using white blood cells removed from blood that is drawn from your body through a vein.\nKymriah is available under a special program. You must be registered in the program and understand the risks and benefits of this medicine.\n','A serious side effect of Kymriah is called cytokine release syndrome, which causes fever, chills, trouble breathing, vomiting, and other symptoms. Your caregivers will have medication available to quickly treat this condition if it occurs.\nKymriah can also cause life-threatening nerve problems. Tell your caregivers or seek emergency medical attention if you have problems with speech, problems with thinking or memory, confusion, or a seizure.\n','This medicine can cause weakness, drowsiness, confusion, problems with memory or coordination, and seizures. Avoid driving or operating machinery for at least 8 weeks after you are treated with Kymriah.\nDo not donate blood, an organ, or any tissues or cells from your own body.\nDo not receive a \"live\" vaccine while using Kymriah, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\nDo not donate blood, an organ, or any tissues or cells from your own body.\n'),(480,'labetalol','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nLabetalol oral is taken by mouth.\nLabetalol injection is given as an infusion into a vein when hypertension is severe. A healthcare provider will give you this injection.\nAfter receiving a labetalol injection, you may need to remain lying down for up to 3 hours. You may feel light-headed when you first stand up.\nYour blood pressure will need to be checked often, and you may need other medical tests.\nKeep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.\nUsing labetalol can make it harder for you to tell when your blood sugar is low. If you have diabetes, check your blood sugar regularly.\nLabetalol can cause false results with certain lab tests of the urine. This medicine also may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use labetalol.\nIf you need surgery, tell the surgeon ahead of time that you are using labetalol.\nYou should not stop using labetalol suddenly. Stopping suddenly may make your condition worse.\nStore at room temperature away from moisture and heat.\n Detailed Labetalol dosage information\nWhat happens if I miss a dose?\nLabetalol oral: Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nBecause you will receive labetalol injection in a clinical setting, you are not likely to miss a dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include slow heart rate, wheezing, chest tightness, trouble breathing, extreme dizziness, seizure, or fainting.\n','Tell your doctor about all your other medicines, especially:\nany other blood pressure medicine;\naminophylline, theophylline;\ncimetidine;\nheart medication;\ninsulin or oral diabetes medicine;\nan antidepressant--amitriptyline, doxepin, desipramine, imipramine, nortriptyline, and others; or\na bronchodilator--albuterol, formoterol, levalbuterol, metaproterenol, olodaterol, salmeterol, and others.\nThis list is not complete. Other drugs may affect labetalol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Labetalol drug interactions (more detail)\nDoes Labetalol interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nslow heart rate, weak pulse, fainting, slow breathing (breathing may stop);\nshortness of breath (even with mild exertion), swelling, rapid weight gain;\nsevere headache, blurred vision, pounding in your neck or ears; or\nliver problems--loss of appetite, stomach pain (upper right side), flu-like symptoms, itching, dark urine, jaundice (yellowing of the skin or eyes).\nSevere dizziness or fainting may be more likely in older adults.\nCommon side effects may include:\ndizziness, drowsiness, tiredness;\nnausea, vomiting;\nsudden warmth, skin redness, sweating;\nnumbness; or\ntingly feeling in your scalp.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Labetalol side effects (more detail)\n','Labetalol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).\nLabetalol is used to treat hypertension (high blood pressure). Labetalol oral is sometimes given with other blood pressure medications.\nLabetalol injection is used when hypertension is severe.\nLabetalol may also be used for purposes not listed in this medication guide.\n','You should not use labetalol if you have asthma, very low blood pressure, or a serious heart condition such as 2nd or 3rd degree \"AV block,\" uncontrolled heart failure, or very slow heartbeats.\nBefore taking this medicine\nYou should not use labetalol if you are allergic to it, or if you have:\nasthma;\n\"AV block\" (2nd or 3rd degree);\nuncontrolled heart failure;\nvery low blood pressure;\nslow heartbeats that have caused you to faint; or\nif your heart cannot pump blood properly.\nTell your doctor if you have ever had:\ncongestive heart failure;\nangina (chest pain);\nliver disease;\nemphysema, chronic bronchitis, or other breathing problems;\npheochromocytoma (tumor of the adrenal gland);\ndiabetes;\ncoronary artery bypass surgery (sometimes called \"CABG\");\nkidney disease; or\nallergies.\nLabetalol can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you use  labetalol.\nIt is not known whether labetalol will harm an unborn baby. Labetalol may cause low blood pressure, low blood sugar, slow heartbeats, or breathing problems in a newborn if the mother uses labetalol during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nLabetalol is not approved for use by anyone younger than 18 years old.\n','Avoid driving or hazardous activity until you know how  labetalol will affect you. Your reactions could be impaired.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy.\nDrinking alcohol can further lower your blood pressure and may increase certain side effects of labetalol.\n'),(481,'lactulose','Usual Adult Dose for Constipation -- Chronic:\n15 mL orally once a day.\nUsual Adult Dose for Constipation -- Acute:\nInitial dose:  15 mL orally once a day.  Therapy should be continued until normal bowel function resumes.\nUsual Adult Dose for Hepatic Encephalopathy:\nInitial dose:  30 mL orally 3 times a day or 300 mL in 700 mL water or normal saline as an enema retained for 30 to 60 minutes every 4 to 6 hours.Maintenance dose:  30 to 45 mL orally 3 times a day.\nUsual Pediatric Dose for Hepatic Encephalopathy:\nInfants: 1.7 to 6.7 g/day (2.5 to 10 mL) orally daily divided in 3 to 4 doses.  Adjust dosage to produce 2 to 3 soft stools per day.Children: 26.7 to 60 g/day (40 to 90 mL) orally daily divided in 3 to 4 doses.  Adjust dosage to produce 2 to 3 soft stools per day.\nUsual Pediatric Dose for Constipation -- Chronic:\nChildren: 0.7 to 2 g/kg/day (1 to 3 mL/kg/day) orally in divided doses daily; generally recommended not to exceed the adult maximum of 40 g/day (60 mL/day).\n Detailed Lactulose dosage information\n','There may be other drugs that can interact with lactulose. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\n Lactulose drug interactions (more detail)\nDoes Lactulose interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using lactulose and call your doctor at once if you have severe or ongoing diarrhea.\nLess serious side effects may include:\nbloating, gas;\nstomach pain;\ndiarrhea; or\nnausea, vomiting.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lactulose side effects (more detail)\n','Lactulose is a type of sugar. It is broken down in the large intestine into mild acids that draw water into the colon, which helps soften the stools.\nLactulose is used to treat chronic constipation.\nLactulose is sometimes used to treat or prevent certain conditions of the brain that are caused by liver failure, which can lead to confusion, problems with memory or thinking, behavior changes, tremors, feeling irritable, sleep problems, loss of coordination, and loss of consciousness.\nLactulose may also be used for purposes not listed in this medication guide.\n','You should not use this medication if you are on a special diet low in galactose (milk sugar).\nBefore taking lactulose, tell your doctor if you have diabetes or if you need to have any type of intestinal test using a scope (such as a colonoscopy).\nIt may take up to 48 hours before you have a bowel movement after taking lactulose.\nStop using lactulose and call your doctor at once if you have severe or ongoing diarrhea.\nThe liquid form of lactulose may become slightly darker in color, but this is a harmless effect. However, do not use the medicine if it becomes very dark, or if it gets thicker or thinner in texture.\nIf you use lactulose over a long period of time, your doctor may want you to have occasional blood tests. Do not miss any scheduled appointments.\nBefore taking this medicine\nYou should not use this medication if you are on a special diet low in galactose (milk sugar).\nTo make sure you can safely take lactulose, tell your doctor if you have other medical conditions, especially:\ndiabetes; or\nif you need to have any type of intestinal test using a scope (such as a colonoscopy).\nFDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.\nIt is not known whether lactulose passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.\nHow should I take lactulose?\nTake exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.\nMeasure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.\nThe liquid form of lactulose may become slightly darker in color, but this is a harmless effect. However, do not use the medicine if it becomes very dark, or if it gets thicker or thinner in texture.\nLactulose powder should be mixed with at least 4 ounces of water. You may also use fruit juice or milk to make the medication taste better.\nIt may take up to 48 hours before you have a bowel movement after taking lactulose.\nIf you use lactulose over a long period of time, your doctor may want you to have occasional blood tests. Do not miss any scheduled appointments.\nStore lactulose at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, and muscle weakness or limp feeling.\n','Avoid using antacids without your doctor\'s advice. Use only the type of antacid your doctor recommends. Some antacids can make it harder for your body to absorb lactulose.\n'),(482,'lamictal','Take Lamictal exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nTaking too much Lamictal at the start of treatment may increase your risk of a severe life-threatening skin rash.\nYou may need frequent blood tests to help your doctor make sure you are taking the right dose.\nExtended-release and immediate-release Lamictal may be used for different conditions. Always check your refills to make sure you have received the correct size, color, and shape of tablet. Avoid medication errors by using only the form and strength your doctor prescribes.\nIf you switch to Lamictal from another seizure medicine, carefully follow your doctor\'s instructions about the timing and dosage of your medicine.\nLamictal tablets should be swallowed whole. Do not crush, chew, or break it.\nLamictal chewable dispersible tablets may be swallowed whole, chewed, or mixed with water or diluted fruit juice.\nRead and carefully follow any Instructions for Use provided with the orally disintegrating or dispersible tablets. Ask your doctor or pharmacist if you do not understand these instructions.\nDo not stop using this medicine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor\'s instructions about tapering your dose.\nIn case of emergency, wear or carry medical identification to let others know you use seizure medication.\nLamotrigine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use lamotrigine.\nStore at room temperature away from light and moisture.\n Detailed Lamictal dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include blurred vision, problems with coordination, increased seizures, feeling light-headed, or fainting.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor if you take any of the following medication, as these drugs may affect Lamictal;\nanti-epileptic medications including valproic acid, divalproex sodium, carbamazepine, phenytoin, phenobarbital, or primidone;\nantibiotics, such as rifampin;\nbirth control pills called oral contraceptives; or\nhuman immunodeficiency virus (HIV) medications including lopinavir/ritonavir or atazanavir/lopinavir\nOther drugs may interact with lamotrigine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Lamictal drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Lamictal (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nIf you have to stop taking lamotrigine because of a serious skin rash, you may not be able to take it again in the future.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nfast, slow, or pounding heartbeats or fluttering in your chest;\nchest pain, shortness of breath;\nfever, swollen glands, weakness, severe muscle pain;\nany skin rash, especially with blistering or peeling;\npainful sores in your mouth or around your eyes;\nheadache, neck stiffness, increased sensitivity to light, nausea, vomiting, confusion, drowsiness;\njaundice (yellowing of the skin or eyes); or\npale skin, cold hands and feet, easy bruising, unusual bleeding.\nCommon Lamictal side effects may include:\nheadache, dizziness;\nblurred vision, double vision;\ntremor, loss of coordination;\ndry mouth, nausea, vomiting, stomach pain, diarrhea;\nfever, sore throat, runny nose;\ndrowsiness, tired feeling;\nback pain; or\nsleep problems (insomnia).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lamictal side effects (more detail)\n','Lamictal (lamotrigine) is an anti-epileptic medication, also called an anticonvulsant.\nLamictal is used alone or with other medications to treat epileptic seizures in adults and children. Lamictal is also used to delay mood episodes in adults with bipolar disorder (manic depression).\nImmediate-release Lamictal can be used in children as young as 2 years old for seizure treatment as an add-on treatment to other seizure medication. However, this form should not be used as a single medication in a child or teenager who is younger than 16 years old.\nExtended-release Lamictal XR is for use only in adults and children who are at least 13 years old.\n','Lamictal may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose, or those who also take valproic acid (Depakene) or divalproex (Depakote). Seek emergency medical attention if you have a skin rash, hives, blistering, peeling, or sores in your mouth or around your eyes.\nCall your doctor at once if you have signs of other serious side effects, including: fever, swollen glands, severe muscle pain, bruising or unusual bleeding, yellowing of your skin or eyes, headache, neck stiffness, vomiting, confusion, or increased sensitivity to light.\nSome people have thoughts about suicide while taking lamotrigine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nDo not stop taking Lamictal without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using this medicine suddenly. Contact your doctor if your seizures get worse or you have them more often while taking this medicine. Taking this medication during early pregnancy can increase the risk of the baby being born with cleft lip or cleft palate. Tell your doctor if you are pregnant or if you become pregnant during treatment.\nBefore taking this medicine\nYou should not take Lamictal if you are allergic to lamotrigine.\nLamictal may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose, or those who also take valproic acid (Depakene) or divalproex (Depakote).\nTell your doctor if you have ever had:\na rash or allergic reaction after taking another seizure medication;\nkidney or liver disease;\nheart problems such as heart block or irregular heartbeats;\ndepression, suicidal thoughts or actions; or\nmeningitis (inflammation of the tissue that covers the brain and spinal cord) after taking Lamictal.\nSome people have thoughts about suicide while taking lamotrigine. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nDo not start or stop taking seizure medication during pregnancy without your doctor\'s advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of lamotrigine on the baby.\nBirth control pills can make lamotrigine less effective, resulting in increased seizures. Tell your doctor if you start or stop using birth control pills. Your lamotrigine dose may need to be changed.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\n','Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(483,'lamotrigine','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nTaking too much lamotrigine at the start of treatment may increase your risk of a severe life-threatening skin rash.\nYou may need frequent blood tests to help your doctor make sure you are taking the right dose.\nExtended-release and immediate-release lamotrigine may be used for different conditions. Always check your refills to make sure you have received the correct size, color, and shape of tablet. Avoid medication errors by using only the form and strength your doctor prescribes.\nIf you switch to lamotrigine from another seizure medicine, carefully follow your doctor\'s instructions about the timing and dosage of your medicine.\nSwallow the tablet whole and do not crush, chew, or break it.\nRead and carefully follow any Instructions for Use provided with the orally disintegrating or dispersible tablets. Ask your doctor or pharmacist if you do not understand these instructions.\nDo not stop using lamotrigine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor\'s instructions about tapering your dose.\nIn case of emergency, wear or carry medical identification to let others know you use seizure medication.\nLamotrigine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use lamotrigine.\nStore at room temperature away from light and moisture.\n Detailed Lamotrigine dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include blurred vision, problems with coordination, increased seizures, feeling light-headed, or fainting.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may affect lamotrigine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Lamotrigine drug interactions (more detail)\nDoes Lamotrigine interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nIf you have to stop taking lamotrigine because of a serious skin rash, you may not be able to take it again in the future.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nfast, slow, or pounding heartbeats or fluttering in your chest;\nchest pain, shortness of breath;\nfever, swollen glands, weakness, severe muscle pain;\nany skin rash, especially with blistering or peeling;\npainful sores in your mouth or around your eyes;\nheadache, neck stiffness, increased sensitivity to light, nausea, vomiting, confusion, drowsiness;\njaundice (yellowing of the skin or eyes); or\npale skin, cold hands and feet, easy bruising, unusual bleeding.\nCommon side effects may include:\nheadache, dizziness;\nblurred vision, double vision;\ntremor, loss of coordination;\ndry mouth, nausea, vomiting, stomach pain, diarrhea;\nfever, sore throat, runny nose;\ndrowsiness, tired feeling;\nback pain; or\nsleep problems (insomnia).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lamotrigine side effects (more detail)\n','Lamotrigine is an anti-epileptic medication, also called an anticonvulsant.\nLamotrigine is used alone or with other medications to treat epileptic seizures in adults and children. Lamotrigine is also used to delay mood episodes in adults with bipolar disorder (manic depression).\nImmediate-release lamotrigine can be used in children as young as 2 years old when it is given as part of a combination of seizure medications. However, this form should not be used as a single medication in a child or teenager who is younger than 16 years old.\nExtended-release lamotrigine is for use only in adults and children who are at least 13 years old.\nLamotrigine may also be used for purposes not listed in this medication guide.\n','Lamotrigine may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose, or those who also take valproic acid (Depakene) or divalproex (Depakote). Seek emergency medical attention if you have a skin rash, hives, blistering, peeling, or sores in your mouth or around your eyes.\nCall your doctor at once if you have signs of other serious side effects, including: fever, swollen glands, severe muscle pain, bruising or unusual bleeding, yellowing of your skin or eyes, headache, neck stiffness, vomiting, confusion, or increased sensitivity to light.\nSome people have thoughts about suicide while taking lamotrigine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nBefore taking this medicine\nYou should not take lamotrigine if you are allergic to it.\nLamotrigine may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose, or those who also take valproic acid (Depakene) or divalproex (Depakote).\nTell your doctor if you have ever had:\na rash or allergic reaction after taking another seizure medication;\nkidney or liver disease;\nheart problems such as heart block or irregular heartbeats;\ndepression, suicidal thoughts or actions; or\nmeningitis (inflammation of the tissue that covers the brain and spinal cord) after taking lamotrigine.\nSome people have thoughts about suicide while taking lamotrigine. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nDo not start or stop taking seizure medication during pregnancy without your doctor\'s advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of lamotrigine on the baby.\nBirth control pills can make lamotrigine less effective, resulting in increased seizures. Tell your doctor if you start or stop using birth control pills. Your lamotrigine dose may need to be changed.\nIt may not be safe to breastfeed while using  lamotrigine. Ask your doctor about any risk.\n','Avoid driving or hazardous activity until you know how  lamotrigine will affect you. Your reactions could be impaired.\n'),(484,'lansoprazole','Use lansoprazole exactly as directed on the label, or as prescribed by your doctor and read all medication guides or instruction sheets.\nLansoprazole is usually taken before eating. Prevacid OTC should be taken in the morning before you eat breakfast.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nShake the lansoprazole oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nSwallow the lansoprazole capsule whole and do not crush, chew, break, or open it.\nRemove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.\nUse lansoprazole for the full prescribed length of time, even if your symptoms quickly improve.\nPrevacid OTC should be taken only once daily for 14 days. It may take up to 4 days for full effect. Allow at least 4 months to pass before you start another 14-day treatment with Prevacid OTC.\nCall your doctor if your symptoms do not improve or if they get worse while you are taking lansoprazole. If you take Prevacid OTC, call your doctor if your heartburn gets worse over the 14-day treatment, or if you need treatment more than once every 4 months.\nSome conditions are treated with a combination of lansoprazole and antibiotics. Use all medications as directed.\nIf you use lansoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.\nStore at room temperature away from moisture, heat, and light. Do not freeze the liquid medicine.\n Detailed Lansoprazole dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sucralfate (Carafate) can make it harder for your body to absorb lansoprazole. Wait at least 30 minutes after taking lansoprazole before you take sucralfate.\nTell your doctor if you use methotrexate.\nSometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can affect lansoprazole, and some drugs should not be used at the same time. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Lansoprazole drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction ro lansoprazole: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody;\nnew or unusual pain in your wrist, back, hip, or thigh;\na seizure (convulsions);\nkidney problems - fever, nausea, little or no urination, blood in your urine, swelling, rapid weight gain;\nlow magnesium - dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or\nnew or worsening symptoms of lupus - joint pain, and a skin rash on your cheeks or arms that worsens in sunlight.\nTaking lansoprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.\nIf you use lansoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.\nCommon lansoprazole side effects may include:\nnausea, stomach pain;\ndiarrhea, constipation; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lansoprazole side effects (more detail)\n','Lansoprazole is a proton pump inhibitor. Lansoprazole decreases the amount of acid produced in the stomach.\nLansoprazole is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome.\nOver-the-counter lansoprazole (Prevacid OTC) is used to treat frequent heartburn that happens 2 or more days per week. This medicine is not for the immediate relief of heartburn symptoms.\n','Lansoprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.\nThis medicine can cause diarrhea, which may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.\nLansoprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.\nYou may be more likely to have a broken bone while taking this medicine long term or more than once per day.\nIf you also take sucralfate (Carafate), avoid taking it at the same time you take this medicine. Sucralfate can make it harder for your body to absorb lansoprazole. Wait at least 30 minutes after taking this medicine before you take sucralfate.\nBefore taking this medicine\nYou should not use lansoprazole if you are allergic to it, or if you take any medicine that contains rilpivirine (Edurant, Complera, Odefsey).\nHeartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.\nTell your doctor if you have ever had:\nliver disease;\nlupus;\nlow levels of magnesium in your blood; or\nosteoporosis or low bone mineral density (osteopenia).\nDo not use over-the-counter lansoprazole (Prevacid OTC) without the advice of a doctor if you have:\ntrouble or pain with swallowing;\nbloody or black stools; vomit that looks like blood or coffee grounds;\nheartburn that has lasted for over 3 months;\nfrequent chest pain, heartburn with wheezing;\nunexplained weight loss;\nnausea or vomiting, stomach pain; or\nan electrolyte imbalance or metabolic disorder.\nSome forms of lansoprazole may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).\nYou may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.\nSome conditions are treated with a combination of lansoprazole and antibiotics. Use all medications as directed by your doctor\nDo not give lansoprazole to a child younger than 1 year old. Prevacid OTC is not approved for use by anyone younger than 18 years old.\nAsk a doctor before using this medicine if you are pregnant or breastfeeding.\n','This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.\n'),(485,'lantus','Use Lantus exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\nIf there are any changes in the brand, strength, or type of insulin you use, your dosage needs may change. The Toujeo brand of insulin glargine contains 3 times as much insulin per milliliter (mL) as the Lantus brand. There are 300 units of insulin in 1 mL of Toujeo, and 100 units in 1 mL of Lantus.\nInsulin is injected under the skin. You will be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.\nLantus must not be given with an insulin pump, or mixed with other insulins. Do not inject insulin glargine into a vein or a muscle.\nDo not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nLantus is usually injected once per day at the same time each day. You will be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.\nYour care provider will show you the best places on your body to inject Lantus. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nIf you use an injection pen, use only the injection pen that comes with Lantus. Attach a new needle before each use. Do not transfer the insulin from the pen into a syringe.\nNever share an injection pen or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nUse a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof \"sharps\" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your insulin dose or schedule.\nLantus is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nKeep this medicine in its original container protected from heat and light. Do not draw insulin from a vial into a syringe until you are ready to give an injection. Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen.\nStoring unopened (not in use) Lantus:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within 28 days.\nStoring opened (in use) Lantus:\nStore the vial in a refrigerator or at room temperature and use within 28 days.\nStore the injection pen at room temperature (do not refrigerate) and use within 28 days.\nDo not store an injection pen with the needle attached.\nDo not use the medicine if it looks cloudy, has changed colors, or has any particles in it. Call your pharmacist for new medicine.\nWear a diabetes medical alert tag in case of emergency. Any medical care provider who treats you should know that you have diabetes.\n Detailed Lantus dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose of Lantus. You should not use more than one dose in a 24-hour period unless your doctor tells you to.\nKeep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell your doctor about the following medications, which can interact with Lantus:\npioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin);\nother anti-diabetic medications;\nblood pressure medications (including ACE-inhibitors, diuretics or water pills, clonidine, beta-blockers;\nbirth control pills;\nthyroid medications;\nanti-depressant medications (especially monoamine oxidase inhibitors or MAOIs, fluoxetine, and others);\nanti-psychotic medications (including olanzapine, clozapine, and others);\ncertain antibiotics, including sulfa drugs; or\ncorticosteroid medications (such as prednisone);\nTell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products.\n Lantus drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergy reaction to Lantus: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nweight gain, swelling in your hands or feet, feeling short of breath; or\nsigns of low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon Lantus side effects may include:\nlow blood sugar;\nitching, mild skin rash; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lantus side effects (more detail)\nBefore taking this medicine\nYou should not use Lantus if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).\nLantus is not approved for use by anyone younger than 6 years old, and should not be used to treat type 2 diabetes in a child of any age.\nTo make sure Lantus is safe for you, tell your doctor if you have:\nliver or kidney disease; or\nlow levels of potassium in your blood (hypokalemia);\nTell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using Lantus if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Lantus (insulin glargine) is a man-made form of a hormone (insulin) that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.\nLantus is used to improve blood sugar control in adults and children with diabetes mellitus.\nLantus is for use in adults with type 1 or type 2 diabetes, and in children at least 6 years old with type 1 diabetes.\nSome brands of insulin glargine are for use only in adults. Carefully follow all instructions for the brand of insulin glargine you are using.\n','You should not use Lantus if you are having an episode of hypoglycemia (low blood sugar), or if you are in a state of diabetic ketoacidosis (call your doctor for treatment).\nNever share a Lantus injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.\nNot all insulin glargine brands are equal in dosing. Follow your doctor’s instructions when changing from one brand to another. If there are any changes in the brand, strength, or type of insulin you use, your dosage needs may change.\nLantus is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.\n','Do not change the brand of insulin glargine or syringe you are using without first talking to your doctor or pharmacist.\nAvoid medication errors by always checking the medicine label before injecting your insulin.\nAvoid drinking alcohol. It can cause low blood sugar and may interfere with your diabetes treatment.\n'),(486,'lasix','Take Lasix exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nDo not take more than your recommended dose. High doses of furosemide may cause irreversible hearing loss.\nMeasure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.\nLasix will make you urinate more often and you may get dehydrated easily. Follow your doctor\'s instructions about using potassium supplements or getting enough salt and potassium in your diet.\nWhile using Lasix, you may need frequent blood tests.\nKeep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.\nIf you need surgery, tell the surgeon ahead of time that you are using Lasix.\nStore at room temperature away from moisture, heat, and light. Throw away any Lasix oral solution (liquid) 90 days after opening the bottle, even if it still contains unused medicine.\n Detailed Lasix dosage information\nWhat happens if I miss a dose?\nLasix is sometimes used only once, so you may not be on a dosing schedule. If you are using the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include feeling very thirsty or hot, heavy sweating, hot and dry skin, extreme weakness, or fainting.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nIf you also take sucralfate, take your furosemide dose 2 hours before or 2 hours after you take sucralfate.\nTell your doctor about all your current medicines and any you start or stop using, especially:\nchloral hydrate;\nlithium;\nphenytoin;\ncancer medicine, such as cisplatin;\nheart or blood pressure medicine; or\nanother diuretic, especially ethacrynic acid.\nThis list is not complete. Other drugs may interact with furosemide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Lasix drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Lasix: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nCall your doctor at once if you have:\nringing in your ears, hearing loss;\neasy bruising, unusual bleeding;\nsudden weakness or ill feeling, fever, chills;\npainful or difficult urination;\nnumbness, tingling, or burning pain;\na light-headed feeling, like you might pass out;\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor;\nsigns of liver or pancreas problems - loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, dark urine, jaundice (yellowing of the skin or eyes);\nkidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or\nsigns of an electrolyte imbalance - dry mouth, increased thirst, mood changes, weakness, drowsiness, lack of energy, muscle pain, fast heartbeats, feeling restless, nausea, vomiting.\nCommon Lasix side effects may include:\ndiarrhea, constipation;\nnumbness or tingling;\nheadache, dizziness; or\nblurred vision.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lasix side effects (more detail)\n','Lasix (furosemide) is a loop diuretic (water pill) that prevents your body from absorbing too much salt. This allows the salt to instead be passed in your urine.\nLasix is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.\nLasix is also used to treat high blood pressure (hypertension).\n','You should not use Lasix if you are unable to urinate.\nDo not take more Lasix than your recommended dose. High doses of furosemide may cause irreversible hearing loss.\nBefore using Lasix, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs.\nTell your doctor if you have recently had an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Do not take more of this medication than is recommended. High doses of furosemide may cause irreversible hearing loss. If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.\nBefore taking this medicine\nYou should not use Lasix if you are allergic to furosemide, or:\nif you are unable to urinate.\nTo make sure Lasix is safe for you, tell your doctor if you have:\nkidney disease;\nenlarged prostate, bladder obstruction, urination problems;\ncirrhosis or other liver disease;\nan electrolyte imbalance (such as low levels of potassium or magnesium in your blood);\nhigh cholesterol or triglycerides (a type of fat in the blood);\ngout;\nlupus;\na thyroid disorder;\ndiabetes; or\nsulfa drug allergy.\nTell your doctor if you have an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Both contrast dyes and furosemide can harm your kidneys.\nIt is not known whether Lasix will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.\nFurosemide can pass into breast milk and may harm a nursing baby. This medicine may also slow breast milk production. Tell your doctor if you are breast-feeding a baby.\n','Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\nAvoid becoming dehydrated. Follow your doctor\'s instructions about the type and amount of liquids you should drink while you are taking Lasix.\nDrinking alcohol with this medicine can cause side effects.\n'),(487,'latanoprost','Administration\nOphthalmic Administration\nApply topically to the affected eye(s) as an ophthalmic emulsion (latanoprost) or ophthalmic solution (latanoprost alone or in fixed combination with netarsudil).        \nAvoid contamination of the dispensing container.   (See Bacterial Keratitis under Cautions.)\nRemove contact lenses before administering each dose; may reinsert lenses 15 minutes after the dose.  \nIf more than one topical ophthalmic preparation is used, administer the preparations at least 5 minutes apart.  \nDosage\nAdults\nOcular Hypertension and Glaucoma\nOphthalmic\nLatanoprost 0.005% ophthalmic solution or emulsion: One drop in the affected eye(s) once daily in the evening.       \nNetarsudil 0.02% and latanoprost 0.005% ophthalmic solution: One drop in the affected eye(s) once daily in the evening.\nMore frequent dosing may diminish the IOP-lowering effect of latanoprost or cause paradoxical elevation of IOP.     \nIf target IOP not achieved, may initiate additional or alternative ocular hypotensive agents.   (See Ocular Hypertension and Glaucoma under Uses.) However, concomitant use of ≥2 prostaglandin analogs not recommended. \nIf a dose is missed, continue the usual schedule with the next dose applied the following evening.   \nSpecial Populations\nNo special population dosage recommendations at this time.  \n Detailed Latanoprost ophthalmic dosage information\n','Specific Drugs\nDrug\nInteraction\nComments\nThimerosal\nOphthalmic preparations containing thimerosal: Precipitation occurs when admixed with latanoprost ophthalmic solution or emulsion  \nAdminister latanoprost and thimerosal-containing preparations ≥5 minutes apart\n Latanoprost ophthalmic drug interactions (more detail)\n',NULL,'Ocular Hypertension and Glaucoma\nLatanoprost 0.005%: Reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension.               \nAppears to be more effective than unoprostone (not available in US), as effective as travoprost, and slightly less effective than bimatoprost in reducing IOP in patients with open-angle glaucoma or ocular hypertension.     \nMay be more effective or at least as effective as twice-daily administration of timolol 0.5% in reducing IOP in patients with open-angle glaucoma or ocular hypertension.         Appears to be more effective than thrice-daily administration of dorzolamide 2%. \nTolerance does not occur, and reduction in mean IOP is maintained for up to at least 24 months of therapy after initial stabilization.        \nFixed-combination netarsudil 0.02% and latanoprost 0.005%: Reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension. When administered once daily, mean IOP reduction was approximately 1–3 mm Hg greater than that achieved with once-daily administration of either drug alone. \nWhen selecting an initial ocular hypotensive agent, consider extent of the required IOP reduction, coexisting medical conditions, and drug characteristics (e.g., dosing frequency, adverse effects, cost).  With single-agent regimens, the reduction in IOP is approximately 25–33% with topical prostaglandin analogs; 20–25% with topical β-adrenergic blocking agents, α-adrenergic agonists, or miotic (parasympathomimetic) agents; 20–30% with oral carbonic anhydrase inhibitors; 18% with topical rho kinase inhibitors; and 15–20% with topical carbonic anhydrase inhibitors. \nA prostaglandin analog frequently is considered for initial therapy in the absence of other considerations (e.g., contraindications, cost considerations, intolerance, adverse effects, patient refusal) because of relatively greater activity, once-daily administration, and low frequency of systemic adverse effects; however, ocular adverse effects can occur.   \nGoal is to maintain an IOP at which visual field loss is unlikely to substantially reduce quality of life during the patient\'s lifetime. \nReduction of pretreatment IOP by ≥25% shown to slow progression of primary open-angle glaucoma.  Set an initial target IOP (based on extent of optic nerve damage and/or visual field loss, baseline IOP at which damage occurred, rate of progression, life expectancy, and other considerations) and reduce IOP toward this goal.   Adjust target IOP up or down as needed over course of disease.  \nCombination therapy with drugs from different therapeutic classes often required to control IOP. \n',NULL,NULL),(488,'latuda','Take Latuda exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nLatuda should be taken with food (at least 350 calories).\nYou may need frequent blood tests.\nIt may take several weeks before your symptoms improve. Keep using the medication as directed. Call your doctor if your symptoms do not improve, or if they get worse while using Latuda.\nYou should not stop using this medicine suddenly. Stopping suddenly may cause other problems.\nIt is easier to become dangerously overheated and dehydrated while you are taking Latuda. Drink plenty of fluids, especially in hot weather and during exercise. You may also be more sensitive to temperature extremes (hot or cold).\nStore at room temperature away from moisture and heat.\n Detailed Latuda dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Using Latuda with other drugs that slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your current medicines. Many drugs can interact with lurasidone, especially:\ndepression or psychotic episodes;\nsleep problems (insomnia);\nhigh blood pressure or a heart rhythm disorder;\nswelling or inflammation;\nseizures; or\nParkinson\'s disease.\nThis list is not complete and many other drugs may interact with lurasidone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Latuda drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Latuda: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nHigh doses or long-term use of Latuda can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include uncontrollable muscle movements of your lips, tongue, eyes, face, arms, or legs. The longer you use lurasidone, the more likely you are to develop this disorder, especially if you are a woman or an older adult.\nCall your doctor at once if you have:\nany new or unusual muscle movements you cannot control;\na light-headed feeling, like you might pass out;\na seizure (convulsions);\n(in women) irregular menstrual periods, breast or vaginal changes, nipple discharge;\n(in men) breast swelling, impotence;\ntrouble swallowing;\nmanic episodes - racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative;\nlow white blood cell counts - fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing;\nhigh blood sugar - increased thirst, increased urination, hunger, dry mouth, fruity breath odor; or\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.\nCommon Latuda side effects may include:\ndrowsiness;\nweight gain;\ntremors, muscle stiffness, slow muscle movement;\nfeeling restless or being unable to sit still;\nnausea, vomiting;\nrunny nose; or\nsleep problems (insomnia).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Latuda side effects (more detail)\n','Latuda (lurasidone) is an antipsychotic medicine. It works by changing the effects of chemicals in the brain.\nLatuda is used to treat schizophrenia in adults and teenagers who are at least 13 years old.\nLatuda is also used to treat episodes of depression associated with bipolar disorder (bipolar depression) in adults and children who are at least 10 years old.\n','Latuda is not approved for use in psychotic conditions related to dementia. Lurasidone may increase the risk of death in older adults with dementia-related psychosis.\nSome young people have thoughts about suicide when taking Latuda. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nBefore you take Latuda, tell your doctor if you have liver disease, kidney disease, heart disease, high blood pressure, heart rhythm problems, a history of heart attack or stroke, high cholesterol or triglycerides, low white blood cell (WBC) counts, seizures, diabetes, Parkinson\'s disease, trouble swallowing, or a history of breast cancer or suicidal thoughts.\nSome medicines can interact with lurasidone and should not be used at the same time. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.\nWhile you are taking Latuda, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medicine.\nLatuda may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\nDrinking alcohol can increase certain side effects of lurasidone. Stop using this medicine and call your doctor at once if you have very stiff (rigid) muscles, high fever, sweating, confusion, fast or pounding heartbeats, feeling like you might pass out, tremors, or twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.\nBefore taking this medicine\nYou should not use Latuda if you are allergic to lurasidone.\nMany drugs can interact and cause dangerous effects. Some drugs should not be used together with lurasidone. Your doctor may change your treatment plan if you also use:\nantifungal medicine such as ketoconazole or voriconazole;\nan antibiotic such as clarithromycin or rifampin;\nan antiviral such as ritonavir;\nSt. John\'s wort; or\nseizure medicine such as carbamazepine or phenytoin.\nLatuda is not approved for use in psychotic conditions related to dementia. Lurasidone may increase the risk of death in older adults with dementia-related conditions.\nTell your doctor if you have ever had:\nheart disease or a stroke;\nhigh or low blood pressure;\nhigh cholesterol or triglycerides (a type of fat in the blood);\ndiabetes or high blood sugar (in you or your family);\na seizure;\nliver or kidney disease;\nlow white blood cell (WBC) counts;\nabnormal hormone function tests (thyroid, pituitary gland);\nbreast cancer; or\nsuicidal thoughts or actions.\nSome people have thoughts about suicide while taking lurasidone. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nTaking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking lurasidone without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of lurasidone on the baby.\nIt may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks.\nLatuda is not approved for schizophrenia in anyone younger than 13 years old. Latuda is not approved for depression in anyone younger than 10 years old.\n','Avoid drinking alcohol. Dangerous side effects could occur.\nAvoid driving or operating machinery until you know how this medicine will affect you. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\nGrapefruit and grapefruit juice may interact with lurasidone and lead to unwanted side effects. Avoid the use of grapefruit products while taking Latuda.\n'),(489,'leflunomide','Usual Adult Dose for Rheumatoid Arthritis:\nLoading dose: 100 mg orally once a day for 3 daysMaintenance: 20 mg orally once a day (If not well tolerated, the dose may be decreased to 10 mg orally once a day)Comment: -Hematology parameters and liver enzymes should be monitored.Use: For the treatment of active rheumatoid arthritis (RA):-To reduce signs and symptoms -To inhibit structural damage as evidenced by X-ray erosions and joint space narrowing-To improve physical function\n Detailed Leflunomide dosage information\n','Leflunomide can cause severe or fatal liver damage. This effect is increased when you also use certain other medicines, including:\nacetaminophen (Tylenol), aspirin, gout or arthritis medication (including gold injections); an NSAID (non-steroidal anti-inflammatory drug)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;\nan antibiotic, antifungal medicine, or sulfa drug; tuberculosis medicine; antiviral or HIV/AIDS medication; medicine to treat mental illness; seizure medication--carbamazepine, phenytoin, valproic acid, and others;\nbirth control pills or hormone replacement therapy; anabolic steroids--methyltestosterone, \"performance-enhancing drugs\"; cancer medication; or\ncholesterol-lowering medication--Crestor, Lipitor, Vytorin, Zocor, and others; heart or blood pressure medication.\nThis list is not complete and many other drugs can interact with leflunomide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you. Not all possible interactions are listed in this medication guide.\n Leflunomide drug interactions (more detail)\nDoes Leflunomide interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsigns of infection--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing;\nsudden chest pain or discomfort, wheezing, dry cough, feeling short of breath;\neasy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;\nnumbness, tingling, or burning pain in your hands or feet;\nliver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or\nsevere skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.\nCommon side effects may include:\nnausea, diarrhea, stomach pain;\nheadache;\nabnormal liver function tests;\nthinning hair;\nback pain;\nweakness;\nrash; or\nhigh blood pressure.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Leflunomide side effects (more detail)\n','Leflunomide affects the immune system and reduces swelling and inflammation in the body.\nLeflunomide is used to treat the symptoms of rheumatoid arthritis.\nLeflunomide may also be used for purposes not listed in this medication guide.\n','Do not use leflunomide if you are pregnant, and stop taking  leflunomide if you think you might be pregnant. Use birth control to prevent pregnancy while you are taking leflunomide, and until you complete a \"drug elimination\" procedure.\nLeflunomide can cause severe or fatal liver damage. Tell your doctor if you have a history of liver disease or if you also use other medicines such as: pain or arthritis medicine (including aspirin, Tylenol, and Advil/Motrin), medicines to treat tuberculosis or other infections, seizure medication, hormonal birth control or hormone replacement therapy, chemotherapy, cholesterol-lowering medicine, heart medication, or blood pressure medicine.\nYour liver function will need to be tested often, and you may need to stop taking leflunomide based on the results of these tests.\nBefore taking this medicine\nYou should not use this medicine if you are allergic to leflunomide or teriflunomide, or if:\nyou are pregnant (you will need to have a negative pregnancy test before starting this treatment);\nyou have severe liver disease; or\nyou are also using teriflunomide.\nDo not use leflunomide if you are pregnant or may become pregnant. Avoid getting pregnant until after you stop taking leflunomide and undergo a \"drug elimination\" procedure to help rid your body of this medicine. Stop taking leflunomide and call your doctor right away if you miss a period or think you might be pregnant.\nTo make sure leflunomide is safe for you, tell your doctor if you have:\na history of liver disease or hepatitis (leflunomide can cause severe liver problems);\na severe or uncontrolled infection;\nkidney disease;\nnerve problems, such as neuropathy caused by diabetes;\na history of tuberculosis;\na weak immune system or bone marrow disorder; or\nif you are using any drugs that weaken your immune system (such as cancer medicine or steroids).\nUse birth control to prevent pregnancy while you are taking this medicine. After you stop taking leflunomide, continue using birth control until you have received blood tests to make sure the drug has been eliminated from your body.\nAsk your doctor if you should use a barrier form of birth control (condom or diaphragm with spermicide). Using hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may increase your risk of liver damage while taking leflunomide.\nIt is not known whether leflunomide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.\nHow should I take leflunomide?\nBefore you start treatment with leflunomide, your doctor may perform tests to make sure you do not have tuberculosis or other infections.\nFollow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use  leflunomide in larger or smaller amounts or for longer than recommended.\nYour blood pressure will need to be checked often.\nLeflunomide can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your leflunomide treatment may be stopped for a short time based on the results of these tests.\nYour liver function will also need to be tested often, and you may need to stop taking leflunomide based on the results of these tests.\nAfter you stop taking leflunomide, you may need to be treated with other medicines to help your body eliminate leflunomide quickly. If you do not undergo this drug elimination procedure, leflunomide could stay in your body for up to 2 years. Follow your doctor\'s instructions.\nYou will also need to go through this drug elimination procedure if you plan to become pregnant after you stop taking leflunomide.\nArthritis is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor\'s advice.\nStore at room temperature away from moisture, heat, and light.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include diarrhea, stomach pain, pale skin, easy bruising or bleeding, dark urine, or jaundice (yellowing of the skin or eyes).\n','Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.\nDo not receive a \"live\" vaccine while using leflunomide, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\n'),(490,'lenvatinib','Usual Adult Dose for Thyroid Cancer:\n24 mg orally once a day\nComment:\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUse: For the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer (DTC)\nUsual Adult Dose for Renal Cell Carcinoma:\n18 mg orally once a day\nComments:\n-This drug is given in combination with 5 mg everolimus.\n-Refer to everolimus prescribing information for recommended dosing information.\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUse: In combination with everolimus for the treatment of patients with advanced renal cell carcinoma (RCC) following one prior anti-angiogenic therapy\nUsual Adult Dose for Hepatocellular Carcinoma:\n-Weight less than 60 kg: 8 mg orally once a day\n-Weight 60 kg or greater: 12 mg orally once a day\nComment:\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUse: For the first-line treatment of patients with unresectable hepatocellular carcinoma (HCC)\nUsual Adult Dose for Endometrial Carcinoma:\n20 mg orally once daily\nComments:\n-This drug is given in combination with pembrolizumab 200 mg IV over 30 minutes every 3 weeks.\n-Refer to the pembrolizumab prescribing information for other dosing information.\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUse: In combination with pembrolizumab for the treatment of patients with advanced endometrial carcinoma that is not microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR), who have disease progression following prior systemic therapy and are not candidates for curative surgery or radiation\n Detailed Lenvatinib dosage information\n','Lenvatinib can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\nTell your doctor about all your other medicines, especially an osteoporosis medicine.\nOther drugs may interact with lenvatinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Lenvatinib drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to lenvatinib: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome people taking lenvatinib have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nAlso call your doctor at once if you have:\nsevere diarrhea;\nheadache, confusion, change in mental status, vision loss, seizure (convulsions);\nlittle or no urination;\nunusual bleeding (nosebleeds, heavy menstrual bleeding), or any other bleeding that will not stop;\nsevere headache, blurred vision, pounding in your neck or ears;\njaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nheart problems - chest pain, pain in your jaw or shoulder, swelling, rapid weight gain, feeling short of breath;\nsigns of a blood clot - sudden numbness or weakness, problems with vision or speech;\nliver problems - dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nlow calcium level - muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon lenvatinib side effects may include:\nbleeding;\nstomach pain, nausea, vomiting, diarrhea;\nloss of appetite, weight loss;\nabnormal thyroid function tests;\nmuscle or joint pain;\nswelling in your arms and legs;\nmouth sores;\nrash;\nredness, itching, or peeling skin on your hands or feet;\nheadache, tiredness; or\ncough, trouble breathing, hoarse voice.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lenvatinib side effects (more detail)\n','Lenvatinib is a kinase inhibitor used to treat certain types of cancer. Kinase inhibitors are enzyme inhibitors that blocks the action of one or more protein kinases.\nLenvatinib is used to treat thyroid cancer. It is usually given after radioactive iodine has been tried without success.\nLenvatinib is used together with everolimus (Afinitor) to treat advanced kidney cancer when other medicines have not been effective.\nLenvatinib is used together with pembrolizumab (Keytruda) to treat a certain type of endometrial cancer (a type of uterine cancer) that has progressed and cannot be removed with surgery or radiation.\nLenvatinib is also used to treat liver cancer that cannot be removed with surgery.\n','Some people taking lenvatinib have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Get emergency medical help if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nCall your doctor at once if you have signs of serious side effects, including: severe chest pain, shortness of breath, swelling in your ankles, numbness or weakness, confusion, severe headache, problems with speech or vision, seizure (convulsions), unusual bleeding, coughing up blood, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).\nBefore taking this medicine\nTo make sure lenvatinib is safe for you, tell your doctor if you have ever had:\nlong QT syndrome (in you or a family member);\nheart disease, high blood pressure;\na heart attack, heart failure, stroke, or blood clot;\nheadaches or vision problems;\nbleeding problems;\na perforation (a hole or tear) in your stomach or intestines;\na seizure disorder;\nkidney disease; or\nliver disease.\nLenvatinib may cause jaw bone problems (osteonecrosis). The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Ask your doctor about your own risk.\nLenvatinib may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 30 days after your last dose.\nPregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.\nDo not breastfeed while using this medicine, and for at least 1 week after your last dose.\nHow should I take lenvatinib?\nTake lenvatinib exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nTake lenvatinib at the same time each day, with or without food.\nTo get a full dose, you may need to take a combination of capsules with different amounts (strengths) of lenvatinib in them. Follow your doctor\'s dosing instructions very carefully.\nSwallow the capsule whole and do not crush, chew, break, or open it.\nIf you cannot swallow a capsule whole, dissolve the capsules in water as follows:\nMeasure 1 tablespoon of water or apple juice and pour the liquid into a small glass.\nPlace only enough capsules for one dose into the liquid. Allow the capsules to dissolve for at least 10 minutes, then stir the mixture for at least 3 more minutes.\nDrink this mixture right away. Add a little more water or juice to the glass, swirl gently and drink right away.\nCall your doctor if you are sick with vomiting or severe diarrhea. Prolonged illness can lead to dehydration and kidney failure.\nCarefully follow your doctor\'s instructions about when to start taking medicine to prevent diarrhea while you are using lenvatinib.\nYou will need frequent medical tests and blood pressure checks.\nPay special attention to your dental hygiene while taking lenvatinib. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using lenvatinib.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(491,'lenvima','Usual Adult Dose for Thyroid Cancer:\n24 mg orally once a day\nComment:\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUsual Adult Dose for Renal Cell Carcinoma:\n18 mg orally once a day\nComments:\n-This drug is given in combination with 5 mg everolimus.\n-Refer to everolimus prescribing information for recommended dosing information.\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUsual Adult Dose for Hepatocellular Carcinoma:\n-Weight less than 60 kg: 8 mg orally once a day\n-Weight 60 kg or greater: 12 mg orally once a day\nComment:\n-Treatment should be continued until disease progression or unacceptable toxicity.\nUsual Adult Dose for Endometrial Carcinoma:\n20 mg orally once daily\nComments:\n-This drug is given in combination with pembrolizumab 200 mg IV over 30 minutes every 3 weeks.\n-Refer to the pembrolizumab prescribing information for other dosing information.\n-Treatment should be continued until disease progression or unacceptable toxicity.\n Detailed Lenvima dosage information\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Lenvima can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\nTell your doctor about all your other medicines, especially an osteoporosis medicine.\nOther drugs may interact with lenvatinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Lenvima drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Lenvima: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome people taking Lenvima have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nAlso call your doctor at once if you have:\nsevere diarrhea;\nheadache, confusion, change in mental status, vision loss, seizure (convulsions);\nlittle or no urination;\nunusual bleeding (nosebleeds, heavy menstrual bleeding), or any other bleeding that will not stop;\nsevere headache, blurred vision, pounding in your neck or ears;\njaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nheart problems - chest pain, pain in your jaw or shoulder, swelling, rapid weight gain, feeling short of breath;\nsigns of a blood clot - sudden numbness or weakness, problems with vision or speech;\nliver problems - dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nlow calcium level - muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon Lenvima side effects may include:\nbleeding;\nstomach pain, nausea, vomiting, diarrhea;\nloss of appetite, weight loss;\nabnormal thyroid function tests;\nmuscle or joint pain;\nswelling in your arms and legs;\nmouth sores;\nrash;\nredness, itching, or peeling skin on your hands or feet;\nheadache, tiredness; or\ncough, trouble breathing, hoarse voice.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lenvima side effects (more detail)\n','Lenvima (lenvatinib) is a kinase inhibitor used to treat certain types of cancer. Kinase inhibitors are enzyme inhibitors that blocks the action of one or more protein kinases which interferes with the growth and spread of cancer cells in the body.\nLenvima is used to treat thyroid cancer. It is usually given after radioactive iodine has been tried without success.\nLenvima is used together with everolimus (Afinitor) to treat advanced kidney cancer when other medicines have not been effective.\nLenvima is used together with pembrolizumab (Keytruda) to treat a certain type of endometrial cancer (a type of uterine cancer) that has progressed and cannot be removed with surgery or radiation.\nLenvima is also used to treat liver cancer that cannot be removed with surgery.\n','Some people taking Lenvima have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Get emergency medical help if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nCall your doctor at once if you have signs of serious side effects, including: severe chest pain, shortness of breath, swelling in your ankles, numbness or weakness, confusion, severe headache, problems with speech or vision, seizure (convulsions), unusual bleeding, coughing up blood, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).\nBefore taking this medicine\nTo make sure Lenvima is safe for you, tell your doctor if you have ever had:\nlong QT syndrome (in you or a family member);\nheart disease, high blood pressure;\na heart attack, heart failure, stroke, or blood clot;\nheadaches or vision problems;\nbleeding problems;\na perforation (a hole or tear) in your stomach or intestines;\na seizure disorder;\nkidney disease; or\nliver disease.\nLenvima may cause jaw bone problems (osteonecrosis). The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Ask your doctor about your own risk.\nLenvatinib may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 30 days after your last dose.\nPregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.\nDo not breastfeed while using Lenvima, and for at least 1 week after your last dose.\nHow should I take Lenvima?\nTake Lenvima exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nTake Lenvima at the same time each day, with or without food.\nTo get a full dose, you may need to take a combination of capsules with different amounts (strengths) of lenvatinib in them. Follow your doctor\'s dosing instructions very carefully.\nSwallow the Lenvima capsule whole and do not crush, chew, break, or open it.\nIf you cannot swallow a capsule whole, dissolve the capsules in water as follows:\nMeasure 1 tablespoon of water or apple juice and pour the liquid into a small glass.\nPlace only enough capsules for one dose into the liquid. Allow the capsules to dissolve for at least 10 minutes, then stir the mixture for at least 3 more minutes.\nDrink this mixture right away. Add a little more water or juice to the glass, swirl gently and drink right away.\nCall your doctor if you are sick with vomiting or severe diarrhea. Prolonged illness can lead to dehydration and kidney failure.\nCarefully follow your doctor\'s instructions about when to start taking medicine to prevent diarrhea while you are using Lenvima.\nYou will need frequent medical tests and blood pressure checks.\nPay special attention to your dental hygiene while taking Lenvima. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using this medicine.\nStore at room temperature away from moisture and heat.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(492,'letrozole','Usual Adult Dose for Breast Cancer:\n2.5 mg orally once a dayDuration of therapy:-Adjuvant and extended adjuvant settings: Optimal duration is unknown; discontinue therapy at relapse.-Advanced disease: Until tumor progression is evident.Uses: -Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer-Extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy-First-line treatment of advanced breast cancer in postmenopausal women with hormone receptor positive or unknown locally advanced or metastatic breast cancer; second-line treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy\nUsual Adult Dose for Breast Cancer -- Adjuvant:\n2.5 mg orally once a dayDuration of therapy:-Adjuvant and extended adjuvant settings: Optimal duration is unknown; discontinue therapy at relapse.-Advanced disease: Until tumor progression is evident.Uses: -Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer-Extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy-First-line treatment of advanced breast cancer in postmenopausal women with hormone receptor positive or unknown locally advanced or metastatic breast cancer; second-line treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy\n Detailed Letrozole dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Other drugs may affect letrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Letrozole drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCommon side effects may include:\nhot flashes, warmth or redness in your face or chest;\nheadache, dizziness, weakness;\nbone pain, muscle or joint pain;\nswelling, weight gain;\nincreased sweating; or\nincreased cholesterol in your blood.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Letrozole side effects (more detail)\n','Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.\nLetrozole is used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.\nLetrozole may also be used for purposes not listed in this medication guide.\n','You should not use letrozole if you are pregnant.\nBefore taking this medicine\nYou should not use letrozole if you are allergic to it.\n letrozole is for use only in women who can no longer get pregnant. Letrozole can harm an unborn baby. Do not use if you are pregnant. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of letrozole. Tell your doctor if you think you may be pregnant.\nTell your doctor if you have ever had:\nliver disease (especially cirrhosis);\nosteoporosis, osteopenia (low bone mineral density);\nhigh cholesterol; or\nif you also take tamoxifen.\nYou should not breastfeed while you are using letrozole and for at least 3 weeks after your last dose.\nHow should I take letrozole?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nYou may take letrozole with or without food.\nYou will need frequent medical tests, and your bone mineral density may also need to be checked.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Avoid driving or hazardous activity until you know how  letrozole will affect you. Your reactions could be impaired.\n'),(493,'leukeran','You must remain under the care of a doctor while you are using Leukeran.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nLeukeran is usually taken for 3 to 6 weeks. Follow your doctor\'s dosing instructions very carefully.\nLeukeran can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results.\nStore Leukeran tablets in the refrigerator.\n Detailed Leukeran dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include agitation, fast heartbeats, skin rash, bruising, bleeding gums, nosebleeds, trouble breathing, or signs of infection (fever, chills, weakness).\n','Other drugs may affect Leukeran, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Leukeran drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nCall your doctor at once if you have:\na seizure;\nan unusual mass or lump;\nsevere vomiting or diarrhea;\nnew or worsening cough;\nbone marrow suppression--dizziness, pale lips or fingernail beds, fast heart rate, getting easily tired or short of breath;\nliver problems--loss of appetite, stomach pain (upper right side), dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or\nlow blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.\nCommon side effects may include:\nbone marrow suppression;\nlow blood cell counts;\nmissed menstrual periods;\nnausea, vomiting, diarrhea; or\nsores or white patches in or around your mouth.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Leukeran side effects (more detail)\n','Leukeran is used to treat several types of cancer, including Hodgkin\'s disease and certain types of leukemia or lymphoma.\nLeukeran may also be used for purposes not listed in this medication guide.\n','Leukeran can increase your risk of bleeding or infection. Call your doctor if you have unusual bruising or bleeding, or new signs of infection (fever, chills, weakness).\nBefore taking this medicine\nYou should not be treated with Leukeran if you are allergic to it, or if you have received this medicine in the past without successful treatment of your condition.\nYou may not be able to receive Leukeran if you\'ve ever had an allergic reaction to another cancer drug such as bendamustine, busulfan, carmustine, dacarbazine, ifosfamide, lomustine, mechlorethamine, melphalan, streptozocin, or temozolomide.\nTell your doctor if you have ever had:\nkidney disease;\nliver disease;\na seizure;\na head injury or brain tumor; or\nif you have received radiation or chemotherapy within the past 4 weeks.\nTaking Leukeran may increase your risk of developing other types of cancer. Talk to your doctor about your specific risk.\nDo not use Leukeran if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using  Leukeran.\nThis medicine may affect fertility (ability to have children) in both men and women. However, women should still use birth control to prevent pregnancy because Leukeran can harm an unborn baby.\nYou should not breastfeed while using this medicine.\n','Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\nAvoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.\nDo not receive a \"live\" vaccine while using Leukeran. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\n'),(494,'levaquin','Take Levaquin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nTake this medicine with water, at the same time each day. Drink extra fluids to keep your kidneys working properly while taking this medicine.\nYou may take Levaquin tablets with or without food.\nTake levofloxacin oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Levaquin will not treat a viral infection such as the flu or a common cold.\nDo not share Levaquin with another person.\nThis medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use levofloxacin.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\n Detailed Levaquin dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Some medicines can make levofloxacin much less effective when taken at the same time. If you take any of the following medicines, take your Levaquin dose 2 hours before or 2 hours after you take the other medicine.\nantacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids), or the ulcer medicine sucralfate (Carafate);\ndidanosine (Videx) powder or chewable tablets; or\nvitamin or mineral supplements that contain aluminum, iron, magnesium, or zinc.\nTo make sure Levaquin is safe for you, tell your doctor if you have ever had:\ntheophylline;\na diuretic or \"water pill\";\nheart rhythm medication;\ninsulin or oral diabetes medicine;\nmedicine to treat depression or mental illness;\nsteroid medicine (such as prednisone);\na blood thinner - warfarin, Coumadin, Jantoven; or\nNSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nThis list is not complete. Other drugs may interact with levofloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Levaquin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nLevaquin can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).\nStop taking this medicine and call your doctor at once if you have:\nlow blood sugar - headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, or feeling anxious or shaky;\nnerve symptoms in your hands, arms, legs, or feet - numbness, weakness, tingling, burning pain;\nserious mood or behavior changes - nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; or\nsigns of tendon rupture - sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions).\nIn rare cases, levofloxacin may cause damage to your aorta, the main blood artery of the body. This could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.\nStop taking Levaquin and call your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody;\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nthe first sign of any skin rash, no matter how mild;\nmuscle weakness, breathing problems;\nseizure (convulsions);\nincreased pressure inside the skull - severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or\nliver problems - upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nnausea, constipation, diarrhea;\nheadache, dizziness; or\ntrouble sleeping.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levaquin side effects (more detail)\n','Levaquin (levofloxacin) is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body.\nLevaquin is used to treat different types of bacterial infections. Levofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague.\nFluoroquinolone antibiotics can cause serious or disabling side effects.\nLevaquin should be used only for infections that cannot be treated with a safer antibiotic.\n','Levaquin can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.\nStop using this medicine and call your doctor at once if you have symptoms such as: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints.\nIn rare cases, levofloxacin may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.\nLevaquin may cause swelling or tearing of a tendon. Stop taking levofloxacin and call your doctor at once if you have sudden pain, swelling, bruising, tenderness, stiffness, or movement problems in any of your joints.\nBefore taking this medicine\nYou should not use Levaquin if you are allergic to levofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, moxifloxacin, norfloxacin, ofloxacin, and others).\nLevaquin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles\' tendon of the heel. This can happen during treatment or up to several months after you stop taking levofloxacin. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).\nTell your doctor if you have ever had:\ntendon problems, bone problems, arthritis or other joint problems (especially in children);\nblood circulation problems, aneurysm, narrowing or hardening of the arteries;\nheart problems, high blood pressure;\na genetic disease such as Marfan syndrome or Ehler\'s-Danlos syndrome;\ndiabetes;\na muscle or nerve disorder, such as myasthenia gravis;\nkidney disease;\nseizures or epilepsy;\na head injury or brain tumor;\nlong QT syndrome (in you or a family member); or\nlow levels of potassium in your blood (hypokalemia).\nDo not give this medicine to a child without medical advice.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.\nYou should not breast-feed while using this medicine.\n','Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\nAntibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.\nLevofloxacin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Tell your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.\n'),(495,'levemir','Use Levemir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nLevemir is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.\nYour healthcare provider will show you where on your body to inject Levemir. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nDo not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nIf you use this medicine once daily, use the injection at your evening meal or at bedtime. If you use the medicine twice daily, use your evening dose at least 12 hours after your morning dose.\nYour doctor may want you to also use a short-acting insulin. Always inject your insulins separately. Levemir must not be given with an insulin pump, or mixed with other insulins. Do not inject into a vein or a muscle.\nIf you use an injection pen, use only the injection pen that comes with Levemir. Attach a new needle before each use. Do not transfer the insulin from the pen into a syringe.\nNever share a Levemir injection pen or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nLevemir is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nKeep this medicine in its original container protected from heat and light. Do not draw insulin from a vial into a syringe until you are ready to give an injection. Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen.\nStoring unopened (not in use) Levemir:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within 42 days.\nStoring opened (in use) Levemir:\nStore the vial in a refrigerator or at room temperature and use within 42 days.\nStore the injection pen at room temperature (do not refrigerate) and use within 42 days. Do not store the injection pen with a needle attached.\nIn case of emergency, wear or carry medical identification to let others know you have diabetes.\n Detailed Levemir dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose. Keep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products.\n Levemir drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Levemir: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nfluid retention - weight gain, swelling in your hands or feet, feeling short of breath; or\nlow potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon Levemir side effects include:\nlow blood sugar;\nweight gain;\nswelling in your hands and feet;\nrash, itching; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levemir side effects (more detail)\n','Levemir (insulin detemir) is a man-made form of insulin, a hormone that is produced in the body. Insulin works by lowering levels of glucose (sugar) in the blood.\nLevemir is a long-acting insulin that starts to work several hours after injection and keeps working evenly for up to 24 hours.\nLevemir is used to improve blood sugar control in people with diabetes mellitus. This medicine is for use in adults and children at least 2 years old.\n','You should not use Levemir if you are allergic to insulin detemir, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with a short-acting insulin).\nNever share a Levemir injection pen or syringe with another person, even if the needle has been changed.\nMany other drugs can potentially interfere with the effects of Levemir. It is extremely important that you tell your doctor about all the prescription and over-the-counter medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\nLow blood sugar (hypoglycemia) can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. An insulin overdose can cause life-threatening hypoglycemia. Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating. Be sure your family and close friends know how to help you in an emergency.\nBefore taking this medicine\nYou should not use Levemir if you are allergic to iinsulin detemir. Do not use during an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment).\nTo make sure Levemir is safe for you, tell your doctor if you have ever had:\nlow levels of potassium in your blood (hypokalemia); or\nliver or kidney disease.\nTell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using Levemir may increase your risk of serious heart problems.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using Levemirif you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Insulin can cause low blood sugar. Avoid driving or operating machinery until you know how this medicine will affect you.\nAvoid medication errors by always checking the medicine label before injecting your insulin.\nAvoid drinking alcohol.\n'),(496,'levetiracetam','Take levetiracetam only as directed by your doctor, to help your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change your dose without checking first with your doctor.\nLevetiracetam comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.\nLevetiracetam may be taken with or without food or on a full or empty stomach. However, if your doctor tells you to take the medicine a certain way, take it exactly as directed. You should try to take levetiracetam at the same time each day.\nSwallow the tablet or the extended-release tablet whole. Do not break, crush, or chew it. There is an oral liquid form of levetiracetam if you or your child cannot swallow the tablets.\nElepsia™ XR extended-release tablet has a blue and white to off-white layer. If you do not see the blue or white, off-white layer, do not take the tablet.\nA part of the tablet may also pass into your stool. This is normal and is nothing to worry about.\nIf you are using the Spritam® tablet or the Spritam® tablet for suspension, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Place the tablet on your tongue and take a sip of water. After it has melted, swallow.\nYou may also add one whole Spritam® tablet for suspension to a small volume of liquid in a cup (1 tablespoon or enough to cover the medicine), and swirl gently. Swallow right away after it has dissolved. Then add a small volume of liquid to cup again, swirl gently, and swallow the liquid.\nMeasure the oral liquid with a marked measuring spoon, dropper, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. If you have any questions about this, ask your doctor or pharmacist.\nLevetiracetam can be used with other seizure medicines. Keep using all of your seizure medicines unless your doctor tells you otherwise.\nTake only the form of levetiracetam that your doctor prescribed. If you refill your prescription and your pills look different, do not take the medicine and tell your doctor or pharmacist right away.\nDosing\nThe dose of levetiracetam will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of levetiracetam. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor oral dosage form (extended-release tablets):\nFor treatment of partial-onset seizures:\nAdults and children 12 years of age and older and weighing 50 kilograms (kg) or more—At first, 1000 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren younger than 12 years of age—Use and dose must be determined by your doctor.\nFor oral dosage form (Keppra® solution or tablets):\nFor partial onset seizures:\nAdults and children 16 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 4 to 15 years of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 10 milligrams (mg) per kilogram (kg) of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per kg of body weight per day.\nChildren 6 months to 3 years of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 10 mg per kg of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 50 mg per kg of body weight per day.\nChildren 1 to 5 months of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 7 mg per kg of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 42 mg per kg of body weight per day.\nChildren younger than 1 month of age—Use and dose must be determined by your doctor.\nFor juvenile myoclonic seizures:\nChildren 12 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren younger than 12 years of age—Use and dose must be determined by your doctor.\nFor primary generalized tonic-clonic seizures:\nAdults and children 16 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 6 to 15 years of age—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 10 milligrams (mg) per kilogram (kg) of body weight 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per kg of body weight per day.\nChildren younger than 6 years of age—Use and dose must be determined by your doctor.\nFor oral dosage forms (Spritam® tablets, Spritam® tablets for suspension):\nFor partial onset seizures:\nAdults and children 4 years of age and older weighing over 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 4 years of age and older weighing 20 to 40 kg—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 250 mg 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1500 mg per day.\nChildren younger than 4 years of age and weighing less than 20 kg—Use is not recommended.\nFor juvenile myoclonic seizures:\nChildren 12 years of age and older—At first, 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren younger than 12 years of age—Use and dose must be determined by your doctor.\nFor primary generalized tonic-clonic seizures:\nAdults and children 6 years of age and older weighing over 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day.\nChildren 6 years of age and older weighing 20 to 40 kg—Dose is based on body weight and must be determined by your doctor. The usual starting dose is 250 mg 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1500 mg per day.\nChildren younger than 6 years of age and weighing less than 20 kg—Use is not recommended.\nMissed dose\nIf you miss a dose of levetiracetam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Levetiracetam dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nMore common\nAggressive or angry\nanxiety\nchange in personality\nchills\ncough\ncrying\ndeep or fast breathing with dizziness\ndelusions of persecution, mistrust, suspiciousness, or combativeness\ndiarrhea\ndry mouth\nfalse or unusual sense of well-being\nfeeling of unreality\nfever\ngeneral feeling of discomfort or illness\nheadache\nhoarseness\nirregular heartbeat\nirritability\njoint pain\nloss of appetite\nlower back or side pain\nmental depression\nmuscle aches and pains\nnausea\nnumbness of the feet, hands, and around the mouth\npainful or difficult urination\nquick to react or overreact emotionally\nrapidly changing moods\nrestlessness\nsense of detachment from self or body\nshaking\nshivering\nsleepiness or unusual drowsiness\nsore throat\nstuffy or runny nose\nsweating\ntrouble sleeping\nunusual tiredness or weakness\nvomiting\nLess common\nBloody nose\nburning, crawling, itching, numbness, prickling, \"pins and needles\", or tingling feelings\nclumsiness or unsteadiness\ndiscouragement\ndizziness or lightheadedness\ndouble vision\nearache\nfeeling of constant movement of self or surroundings\nfeeling sad or empty\nincrease in body movements\nloss of bladder control\nloss of memory\nmood or mental changes\noutburst of anger\npain or tenderness around the eyes and cheekbones\nproblems with memory\nredness or swelling in the ear\nseizures\nsensation of spinning\nshakiness and unsteady walk\nshakiness in the legs, arms, hands, or feet\ntightness of the chest\ntrembling or shaking of the hands or feet\ntrouble concentrating\nunsteadiness, trembling, or other problems with muscle control or coordination\nIncidence not known\nAttempts at killing oneself\nbeing forgetful\nbleeding gums\nblistering, peeling, or loosening of the skin\nbloating\nblood in the urine or stools\nbloody, black, or tarry stools\nblurred vision\nchanges in vision\nchest pain\nconstipation\ndark urine\ndifficulty with moving\nfast heartbeat\nfever with or without chills\ngeneral feeling of tiredness or weakness\nhigh fever\nindigestion\nitching\nlight-colored stools\nmuscle pains or stiffness\npains in the stomach, side, or abdomen, possibly radiating to the back\npale skin\npinpoint red spots on the skin\nred skin lesions, often with a purple center\nred, irritated eyes\nskin rash, encrusted, scaly, and oozing\nsores, ulcers, or white spots on the lips or in the mouth\nstomach pain, continuing\nswollen glands\nswollen joints\nthoughts or attempts at killing oneself\ntrouble with balance\ntwitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs\nuncontrolled jerking or twisting movements of the hands, arms, or legs\nuncontrolled movements of the lips, tongue, or cheeks\nunexplained bleeding or bruising\nunusual bleeding or bruising\nupper right abdominal or stomach pain\nweight loss\nyellow eyes or skin\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nMore common\nLoss of strength or energy\nmuscle pain or weakness\npain\ntender, swollen glands in the neck\ntrouble swallowing\nunusual weak feeling\nvoice changes\nLess common\nBody aches or pain\nburning, dry, or itching eyes\nchange in the color of the skin\ncongestion\ncough increased\nsneezing\nIncidence not known\nHair loss or thinning of the hair\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Levetiracetam side effects (more detail)\n','Levetiracetam is used to control certain types of seizures in the treatment of epilepsy. Levetiracetam cannot cure epilepsy and will only work to control seizures for as long as you continue to use it.\nLevetiracetam is available only with your doctor\'s prescription.\n','It is very important that your doctor check your or your child\'s progress at regular visits, especially for the first few months you or your child are using levetiracetam. This is necessary to allow dose adjustments and to reduce any unwanted effects.\nLevetiracetam may cause changes in mood or behavior, problems with coordination, or unusual tiredness or weakness. Tell your doctor right away if you or your child start to feel depressed, anxious, angry, getting upset easily, restless, or have thoughts about hurting yourself. Report any unusual thoughts or behavior that trouble you, especially if they are new or getting worse quickly.\nLevetiracetam may cause some people to become dizzy, drowsy, tired, or less alert than they are normally. Do not drive or do anything else that could be dangerous until you know how levetiracetam affects you.\nLevetiracetam may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using levetiracetam.\nSerious skin reactions can occur with levetiracetam. Check with your doctor right away if you or your child have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using levetiracetam.\nDo not stop using levetiracetam without first checking with your doctor. Stopping the medicine suddenly may cause your seizures to return or to occur more often. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely.\nMake sure any doctor or dentist who treats you knows that you are using levetiracetam. Levetiracetam may affect the results of certain medical tests.\n',NULL),(497,'levocetirizine','Usual Adult Dose for Urticaria:\n5 mg orally once a day in the eveningComments: Some patients may be adequately controlled on 2.5 mg orally once a day in the evening.Use: For the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria\nUsual Adult Dose for Allergic Rhinitis:\nSeasonal Allergic Rhinitis (OTC): 5 mg orally once a day in the evening; some patients may be adequately controlled on 2.5 mg once a day\nUsual Pediatric Dose for Allergic Rhinitis:\nPerennial Allergic Rhinitis:6 months to 2 years: 1.25 mg orally once a day in the eveningComments: The recommended dose in pediatric patients 6 months to 2 years should not be exceeded.Use: For the relief of symptoms associated with perennial allergic rhinitisSeasonal Allergic Rhinitis (OTC):6 to 11 years: 2.5 mg orally once a day in the evening12 years or older: 5 mg orally once a day in the evening; some patients may be adequately controlled on 2.5 mg once a dayComments: Avoid use in patients less than 6 years.\nUsual Pediatric Dose for Urticaria:\n6 months to 5 years: 1.25 mg orally once a day in the evening6 to 11 years: 2.5 mg orally once a day in the evening12 years or older: 5 mg orally once a day in the evening; some patients may be adequately controlled on 2.5 mg once a dayComments: The recommended doses in pediatric patients 6 months to 12 years should not be exceeded.Use: For the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria\n Detailed Levocetirizine dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Using levocetirizine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your other medicines, especially:\nritonavir; or\ntheophylline.\nThis list is not complete. Other drugs may affect levocetirizine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Levocetirizine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nStop using levocetirizine and call your doctor at once if you have:\nworsening allergy or urticaria symptoms;\npainful or difficult urination;\nlittle or no urination;\na light-headed feeling, like you might pass out;\nfever; or\nsigns of an ear infection--ear pain or full feeling, trouble hearing, drainage from the ear, fussiness in a child.\nCommon side effects may include:\ndrowsiness, tiredness;\nsinus pain;\near infection;\ncough;\nfever;\nnosebleed;\nvomiting, diarrhea, constipation;\ndry mouth; or\nweight gain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levocetirizine side effects (more detail)\n','Levocetirizine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms such as a runny nose or hives.\nLevocetirizine is used to treat symptoms of year-round (perennial) allergies in children who are at least 6 months old.\nLevocetirizine is also used to treat itching and swelling caused by chronic urticaria (hives) in adults and children who are at least 6 months old.\nLevocetirizine may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use  levocetirizine if you are allergic to levocetirizine or cetirizine (Zyrtec).\nYou should not take levocetirizine if you have end-stage kidney disease or if you are on dialysis. Any child younger than 12 years old with kidney disease should not take levocetirizine.\nTell your doctor if you have ever had:\nkidney disease;\nliver disease;\nurination problems (caused by conditions such as enlarged prostate or spinal cord lesion); or\ngallbladder problems.\nLevocetirizine is not expected to harm an unborn baby. Tell your doctor if you are pregnant.\nYou should not breast-feed while using this medicine.\nLevocetirizine is not approved for use by anyone younger than 6 months old.\nHow should I take levocetirizine?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nA child\'s dose of levocetirizine is based on the age of the child. Follow your doctor\'s dosing instructions very carefully.\nDo not give a child more than the prescribed dose of this medicine. A child\'s body absorbs twice as much of the same dose size of levocetirizine as an adult\'s body.\nTaking more of this medication will not make it more effective, and may cause severe drowsiness.\nLevocetirizine is usually taken in the evening, with or without food.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nCall your doctor if your symptoms do not improve, if they get worse, or if you also have a fever.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Avoid driving or hazardous activity until you know how  levocetirizine will affect you. Your reactions could be impaired.\nDrinking alcohol with this medicine can cause side effects.\n'),(498,'levodopa-inhalation','Usual Adult Dose for Parkinson\'s Disease:\n84 mg via oral inhalation as needed when OFF period starts to return; may dose up to 5 times a dayMaximum dose per OFF period: 84 mgMaximum daily dose: 420 mgComments:-Therapy should be taken when symptoms of an OFF period start to return.  -This drug has shown efficacy only in combination with levodopa/carbidopa therapy.-Oral inhalation capsules should only be used with the Inbrija(R) inhaler; capsules should not be swallowed whole as the intended effect will not be obtained.  Use: For the intermittent treatment of OFF episodes in patients with Parkinson\'s disease treated with carbidopa/levodopa.\n Detailed Levodopa dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Using levodopa inhalation with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your other medicines, especially:\nisoniazid;\nmetoclopramide;\nrisperidone or other antipsychotic medication;\niron medication, such as ferrous fumarate, ferrous gluconate, or ferrous sulfate;\na multivitamin or mineral supplement that contains iron; or\nother medicines to treat Parkinson\'s disease.\nThis list is not complete. Other drugs may affect levodopa inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Levodopa drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using levodopa inhalation and call your doctor or seek emergency medical attention if you have a wheezing, chest tightness, or trouble breathing after inhaling this medicine.\nCall your doctor at once if you have:\nextreme drowsiness, falling asleep suddenly (even after feeling alert);\nnausea, sweating, and a light-headed feeling (like you might pass out);\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\nconfusion, paranoia, hallucinations (seeing or hearing things that are not real);\nunusual thoughts or behavior;\ntrouble sleeping, or increased dreaming;\nagitation, aggression; or\nincreased sexual urges, unusual urges to gamble, or other intense urges.\nSome people using this medicine have fallen asleep during normal daytime activities such as working, talking, eating, or driving. This side effect has occurred up to 1 year after the start of treatment with levodopa inhalation. Tell your doctor if you have any problems with daytime drowsiness.\nCommon side effects may include:\ncough;\ncold symptoms such as stuffy nose, sneezing, sore throat;\nnausea; or\nsweat, urine, or saliva that appears dark in color.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levodopa side effects (more detail)\n','Levodopa inhalation is used to treat symptoms of Parkinson\'s disease that come back (OFF episodes) while you are taking another medicine called carbidopa and levodopa.\nLevodopa inhalation is not to be used in place of any medicine you take daily for Parkinson\'s disease.\nLevodopa inhalation may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nDo not use levodopa inhalation if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nTell your doctor if you have ever had:\nasthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;\nglaucoma;\ninvoluntary muscle movements;\na sleep disorder that causes daytime sleepiness;\ndizziness, nausea, or fainting spells when standing from a sitting or lying position;\nmental illness or psychosis; or\nan intense urge or compulsive behavior (such as sexual urges, binge eating, gambling, or spending money).\nIt is not known whether  levodopa inhalation will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nHow should I use levodopa inhalation?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nLevodopa inhalation is for use only in people who are currently taking carbidopa and levodopa. Do not stop taking your daily Parkinson\'s medications or change your dosing schedule without your doctor\'s advice.\nFor best results, use levodopa inhalation when an \"off episode\" begins (when your Parkinson\'s symptoms start to return). Do not use levodopa inhalation more than 5 times per day.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nLevodopa inhalation (Inbrija) is a powder that comes with a special inhaler device and blister packs containing capsules of the medicine. You will load 2 capsules (one at a time) into the inhaler device each time you use the medicine. Pushing the handle of the device onto the mouthpiece will pierce the capsule and release the medicine into the inhaler.\nDo not swallow a levodopa inhalation capsule. It is for use only in the Inbrija inhaler device.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using levodopa inhalation.\nDo not stop using levodopa inhalation suddenly after long-term regular use, or you could have unpleasant withdrawal symptoms (fever, confusion, muscle stiffness, changes in breathing and heart rate). Ask your doctor how to safely stop using this medicine.\nStore at room temperature away from moisture and heat. Keep each capsule in the blister pack until you ready to load the inhaler device. Do not store capsules inside the device.\nThrow away the device when your capsules run out. Always use the inhaler device that comes with each new prescription.\nWhat happens if I miss a dose?\nSince levodopa inhalation is used when needed, you may not be on a dosing schedule. Skip any missed dose if it\'s almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include muscle pain or weakness, fever, dark colored urine, little or no urination, fast heartbeats, or fainting.\n','Avoid driving or hazardous activity until you know how  levodopa inhalation will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\n'),(499,'levofloxacin','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake levofloxacin with water, at the same time each day. Drink extra fluids to keep your kidneys working properly while taking  levofloxacin.\nYou may take levofloxacin tablets with or without food.\nTake levofloxacin oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Levofloxacin will not treat a viral infection such as the flu or a common cold.\nDo not share levofloxacin with another person.\nThis medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use levofloxacin.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\n Detailed Levofloxacin dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Some medicines can make levofloxacin much less effective when taken at the same time. If you take any of the following medicines, take your levofloxacin dose 2 hours before or 2 hours after you take the other medicine.\nantacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids), or the ulcer medicine sucralfate (Carafate);\ndidanosine (Videx) powder or chewable tablets; or\nvitamin or mineral supplements that contain aluminum, iron, magnesium, or zinc.\nTell your doctor about all your other medicines, especially:\ntheophylline;\na diuretic or \"water pill\";\nheart rhythm medication;\ninsulin or oral diabetes medicine (check your blood sugar regularly);\nmedicine to treat depression or mental illness;\nsteroid medicine (such as prednisone);\na blood thinner--warfarin, Coumadin, Jantoven; or\nNSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nThis list is not complete. Other drugs may affect levofloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Levofloxacin drug interactions (more detail)\nDoes Levofloxacin interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nLevofloxacin can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).\nStop taking this medicine and call your doctor at once if you have:\nlow blood sugar--headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, or feeling anxious or shaky;\nnerve symptoms in your hands, arms, legs, or feet--numbness, weakness, tingling, burning pain;\nserious mood or behavior changes--nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; or\nsigns of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions).\nIn rare cases, levofloxacin may cause damage to your aorta, the main blood artery of the body. This could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.\nStop taking levofloxacin and call your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody;\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nthe first sign of any skin rash, no matter how mild;\nmuscle weakness, breathing problems;\nseizure (convulsions);\nincreased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or\nliver problems--upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nnausea, constipation, diarrhea;\nheadache, dizziness; or\ntrouble sleeping.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levofloxacin side effects (more detail)\n','Levofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Levofloxacin is used to treat different types of bacterial infections. Levofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague.\nFluoroquinolone antibiotics can cause serious or disabling side effects. Levofloxacin should be used only for infections that cannot be treated with a safer antibiotic.\nLevofloxacin may also be used for purposes not listed in this medication guide.\n','Levofloxacin can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.\nStop using  levofloxacin and call your doctor at once if you have symptoms such as: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints.\nIn rare cases, levofloxacin may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.\nBefore taking this medicine\nYou should not use this medicine if you are allergic to levofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, moxifloxacin, norfloxacin, ofloxacin, and others).\nLevofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles\' tendon of the heel. This can happen during treatment or up to several months after you stop taking levofloxacin. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).\nTell your doctor if you have ever had:\ntendon problems, bone problems, arthritis or other joint problems (especially in children);\nblood circulation problems, aneurysm, narrowing or hardening of the arteries;\nheart problems, high blood pressure;\na genetic disease such as Marfan syndrome or Ehler\'s-Danlos syndrome;\ndiabetes;\na muscle or nerve disorder, such as myasthenia gravis;\nkidney disease;\nseizures or epilepsy;\na head injury or brain tumor;\nlong QT syndrome (in you or a family member); or\nlow levels of potassium in your blood (hypokalemia).\nDo not give this medicine to a child without medical advice.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.\nYou should not breast-feed while using this medicine.\n','Avoid driving or hazardous activity until you know how  levofloxacin will affect you. Your reactions could be impaired.\nAntibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.\nLevofloxacin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Tell your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.\n'),(500,'levothyroxine','Take levothyroxine exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nLevothyroxine oral is taken by mouth. The injection is given as an infusion into a vein. Levothyroxine is usually given by injection only if you are unable to take the medicine by mouth.\nLevothyroxine oral works best if you take it on an empty stomach, 30 to 60 minutes before breakfast. Follow your doctor\'s dosing instructions and try to take the medicine at the same time each day.\nSwallow the tablet or capsule whole, with a full glass (8 ounces) of water. The tablet may dissolve very quickly and could swell in your throat.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nLevothyroxine doses are based on weight in children. Your child\'s dose needs may change if the child gains or loses weight.\nIt may take several weeks before your body starts to respond to levothyroxine. Keep using this medicine even if you feel well. You may need to use this medicine for the rest of your life.\nYou may need frequent medical tests. Tell any doctor, dentist, or surgeon who treats you that you are using this medicine.\nStore at room temperature away from moisture and heat.\nDo not share this medicine with another person, even if they have the same symptoms you have.\n Detailed Levothyroxine dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include headache, leg cramps, tremors, feeling nervous or irritable, chest pain, shortness of breath, and fast or pounding heartbeats.\n','Many other medicines can be affected by your thyroid hormone levels. Certain other medicines may also increase or decrease the effects of levothyroxine.\nCertain medicines can make this medicine less effective if taken at the same time. If you use any of the following drugs, avoid taking them within 4 hours before or 4 hours after you take levothyroxine:\ncalcium carbonate (Alka-Mints, Caltrate, Os-Cal, Oyster Shell Calcium, Rolaids Soft Chew, Tums, and others);\ncholestyramine, colesevelam, colestipol;\nferrous sulfate iron supplement;\nsucralfate;\nsodium polystyrene sulfonate (Kalexate, Kayexalate, Kionex);\nstomach acid reducers - esomeprazole, lansoprazole, omeprazole, rabeprazole, Nexium, Prilosec, Prevacid, Protonix, Zegerid, and others; or\nantacids that contain aluminum or magnesium - Gaviscon, Maalox, Milk of Magnesia, Mintox, Mylanta, Pepcid Complete, and others.\nMany drugs can interact with levothyroxine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Levothyroxine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to levothyroxine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nfast or irregular heartbeats;\nchest pain, pain spreading to your jaw or shoulder;\nshortness of breath;\nfever, hot flashes, sweating;\ntremors, or if you feel unusually cold;\nweakness, tiredness, sleep problems (insomnia);\nmemory problems, feeling depressed or irritable;\nheadache, leg cramps, muscle aches;\nfeeling nervous or irritable;\ndryness of your skin or hair, hair loss;\nirregular menstrual periods; or\nvomiting, diarrhea, appetite changes, weight changes.\nCertain side effects may be more likely in older adults.\nCommon levothyroxine side effects may include:\nchest pain, irregular heartbeats;\nshortness of breath;\nheadache, leg cramps, muscle pain or weakness;\ntremors, feeling nervous or irritable, trouble sleeping;\nincreased appetite;\nfeeling hot;\nweight loss;\nchanges in your menstrual periods;\ndiarrhea; or\nskin rash, partial hair loss.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levothyroxine side effects (more detail)\n','Levothyroxine is a thyroid medicine that replaces a hormone normally produced by your thyroid gland to regulate the body\'s energy and metabolism.\nLevothyroxine is used to treat hypothyroidism (low thyroid hormone). This medicine is given when your thyroid does not produce enough of this hormone on its own.\nLevothyroxine is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.\n','You may not be able to take levothyroxine if you have certain medical conditions. Tell your doctor if you have an untreated or uncontrolled adrenal gland disorder, a thyroid disorder called thyrotoxicosis, or if you have any recent or current symptoms of a heart attack.\nLevothyroxine should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of this medicine, especially if you are taking any other weight-loss medications or appetite suppressants.\nBefore taking this medicine\nLevothyroxine should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of levothyroxine, especially if you are taking any other weight-loss medications or appetite suppressants.\nSince thyroid hormone occurs naturally in the body, almost anyone can take levothyroxine. However, you may not be able to take this medicine if you have certain medical conditions. Tell your doctor if you have:\nan untreated or uncontrolled adrenal gland disorder;\na thyroid disorder called thyrotoxicosis; or\nsymptoms of a heart attack (chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling).\nTo make sure levothyroxine is safe for you, tell your doctor if you have ever had:\na thyroid nodule;\nheart disease, a blood clot, or a blood-clotting disorder;\ndiabetes (insulin or oral diabetes medication doses may need to be changed when you start taking this medicine);\nkidney disease;\nanemia (lack of red blood cells);\nosteoporosis, or low bone mineral density;\nproblems with your pituitary gland; or\nany food or drug allergies.\nTell your doctor if you have recently received radiation therapy with iodine (such as I-131).\nIf you become pregnant while taking levothyroxine, do not stop taking the medicine without your doctor\'s advice. Having low thyroid hormone levels during pregnancy could harm both mother and baby. Your dose needs may be different during pregnancy.\nTell your doctor if you are breastfeeding. Your dose needs may be different while you are nursing.\nDo not give this medicine to a child without medical advice. Tirosint is not approved for use by anyone younger than 6 years old.\n','Avoid the following food products, which can make your body absorb less levothyroxine: grapefruit juice, infant soy formula, soybean flour, cotton seed meal, walnuts, and high-fiber foods.\n'),(501,'levoxyl','Take Levoxyl exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nLevoxyl is taken by mouth.\nLevoxyl works best if you take it on an empty stomach, 30 to 60 minutes before breakfast. Follow your doctor\'s dosing instructions and try to take the medicine at the same time each day.\nSwallow the tablet whole, with a full glass (8 ounces) of water. The Levoxyl tablet may dissolve very quickly and could swell in your throat.\nWhen giving Levoxyl to infants and children who cannot swallow tablets the tablets may be crushed. Place the freshly crushed tablet in a small amount (5 mL to 10 mL or 1 to 2 teaspoonfuls) of water and immediately give the medicine by spoon or dropper. Do not store the mixed medicine or mix it with foods that decrease the absorption of levothyroxine, such as soybean-based infant formula.\nIt may take several weeks before your body starts to respond to levothyroxine. Keep using Levoxyl even if you feel well. You may need to use for the rest of your life.\nYou may need frequent medical tests. Tell any doctor, dentist, or surgeon who treats you that you are using .\nStore at room temperature away from moisture and heat.\nDo not share Levoxyl with another person, even if they have the same symptoms you have.\n Detailed Levoxyl dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include headache, leg cramps, tremors, feeling nervous or irritable, chest pain, shortness of breath, and fast or pounding heartbeats.\n','Many other medicines can be affected by your thyroid hormone levels. Certain other medicines may also increase or decrease the effects of levothyroxine.\nCertain medicines can make levothyroxine less effective if taken at the same time. If you use any of the following drugs, avoid taking them within 4 hours before or 4 hours after you take :\ncalcium carbonate (Alka-Mints, Caltrate, Os-Cal, Oyster Shell Calcium, Rolaids Soft Chew, Tums, and others);\ncholestyramine, colesevelam, colestipol;\nferrous sulfate iron supplement;\nsucralfate;\nsodium polystyrene sulfonate (Kalexate, Kayexalate, Kionex);\nstomach acid reducers - esomeprazole, lansoprazole, omeprazole, rabeprazole, Nexium, Prilosec, Prevacid, Protonix, Zegerid, and others; or\nantacids that contain aluminum or magnesium - Gaviscon, Maalox, Milk of Magnesia, Mintox, Mylanta, Pepcid Complete, and others.\nMany drugs can interact with levothyroxine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Levoxyl drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Levoxyl: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nfast or irregular heartbeats;\nchest pain, pain spreading to your jaw or shoulder;\nshortness of breath;\nfever, hot flashes, sweating;\ntremors, or if you feel unusually cold;\nweakness, tiredness, sleep problems (insomnia);\nmemory problems, feeling depressed or irritable;\nheadache, leg cramps, muscle aches;\nfeeling nervous or irritable;\ndryness of your skin or hair, hair loss;\nirregular menstrual periods; or\nvomiting, diarrhea, appetite changes, weight changes.\nCertain side effects may be more likely in older adults.\nCommon Levoxyl side effects may include:\nchest pain, irregular heartbeats;\nshortness of breath;\nheadache, leg cramps, muscle pain or weakness;\ntremors, feeling nervous or irritable, trouble sleeping;\nincreased appetite;\nfeeling hot;\nweight loss;\nchanges in your menstrual periods;\ndiarrhea; or\nskin rash, partial hair loss.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Levoxyl side effects (more detail)\n','Levoxyl (levothyroxine) is a thyroid medicine that replaces a hormone normally produced by your thyroid gland to regulate the body\'s energy and metabolism. Levothyroxine is given when your thyroid does not produce enough of this hormone on its own.\nLevoxyl is a prescription medicine used to treat hypothyroidism (low thyroid hormone).\nLevoxyl is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.\nLevoxyl is also used in patients who need surgery and radioiodine therapy to manage a type of thyroid cancer called well-differentiated thyroid cancer.\n','You may not be able to take Levoxyl if you have certain medical conditions. Tell your doctor if you have an untreated or uncontrolled adrenal gland disorder, a thyroid disorder called thyrotoxicosis, or if you have any recent or current symptoms of a heart attack.\nLevoxyl should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of this medicine, especially if you are taking any other weight-loss medications or appetite suppressants.\nBefore taking this medicine\nLevoxyl should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of levothyroxine, especially if you are taking any other weight-loss medications or appetite suppressants.\nSince thyroid hormone occurs naturally in the body, almost anyone can take Levoxyl. However, you may not be able to take this medicine if you have certain medical conditions. Tell your doctor if you have:\nan untreated or uncontrolled adrenal gland disorder;\na thyroid disorder called thyrotoxicosis; or\nsymptoms of a heart attack (chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling).\nTo make sure Levoxyl is safe for you, tell your doctor if you have ever had:\na thyroid nodule;\nheart disease, a blood clot, or a blood-clotting disorder;\ndiabetes (insulin or oral diabetes medication doses may need to be changed when you start taking Levoxyl);\nkidney disease;\nanemia (lack of red blood cells);\nosteoporosis, or low bone mineral density;\nproblems with your pituitary gland; or\nany food or drug allergies.\nTell your doctor if you have recently received radiation therapy with iodine (such as I-131).\nIf you become pregnant while taking Levoxyl, do not stop taking the medicine without your doctor\'s advice. Having low thyroid hormone levels during pregnancy could harm both mother and baby. Your dose needs may be different during pregnancy.\nTell your doctor if you are breast-feeding. Your dose needs may be different while you are nursing.\nDo not give Levoxyl to a child without medical advice.\n','Avoid the following food products, which can make your body absorb less levothyroxine: grapefruit juice, infant soy formula, soybean flour, cotton seed meal, walnuts, and high-fiber foods.\n'),(502,'lexapro','Usual Adult Dose for Generalized Anxiety Disorder:\nInitial dose: 10 mg orally once a day; increase if necessary after at least 1 week of treatment to 20 mg once a day\nMaintenance dose: 10 to 20 mg orally once a day\nMaximum dose: 20 mg orally once a day\nComment: Treatment should be periodically reassessed to determine the need for ongoing treatment; efficacy beyond 8 weeks has not been systematically studied.\nUse: Acute treatment of generalized anxiety disorder\nUsual Adult Dose for Depression:\nInitial dose: 10 mg orally once a day; increase if necessary after at least 1 week of treatment to 20 mg once a day\nMaintenance dose: 10 to 20 mg orally once a day\nMaximum dose: 20 mg orally once a day\nComments:\n-Acute episodes may require several months or longer of sustained pharmacological therapy beyond response to the acute episode.\n-Patients should be periodically reassessed to determine the need for maintenance treatment.\nUse: Acute and maintenance treatment of major depressive disorder\nUsual Geriatric Dose for Depression:\nRecommended dose: 10 mg orally once a day\nUse: Acute and maintenance treatment of major depressive disorder\nUsual Pediatric Dose for Depression:\n12 years and older:\n-Initial dose: 10 mg orally once a day; increase if necessary after at least 3 weeks of treatment to 20 mg once a day\n-Maintenance dose: 10 to 20 mg orally once a day\n-Maximum dose: 20 mg orally once a day\nComments:\n-Acute episodes may require several months or longer of sustained pharmacological therapy beyond response to the acute episode.\n-Patients should be periodically reassessed to determine the need for maintenance treatment.\nUse: Acute and maintenance treatment of major depressive disorder\n Detailed Lexapro dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Using Lexapro with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your current medicines, especially a blood thinner such as warfarin, Coumadin, or Jantoven.\nMany drugs may interact with escitalopram, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Lexapro drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Lexapro: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nblurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;\nracing thoughts, unusual risk-taking behavior, feelings of extreme happiness or sadness;\npain or burning when you urinate;\n(in a child taking Lexapro) slow growth or weight gain;\nlow levels of sodium in the body - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; or\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nCommon Lexapro side effects may include:\npainful urination;\ndizziness, drowsiness, tiredness, weakness;\nfeeling anxious or agitated;\nincreased muscle movements, feeling shaky;\nsleep problems (insomnia);\nsweating, dry mouth, increased thirst, loss of appetite;\nnausea, constipation;\nyawning;\nnosebleed, heavy menstrual periods; or\ndecreased sex drive, impotence, or difficulty having an orgasm.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lexapro side effects (more detail)\n','Lexapro (escitalopram) is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Escitalopram affects the levels of certain chemicals in the brain that may be altered in people suffering from depression or anxiety.\nLexapro is used to treat major depressive disorder in adults and adolescents at least 12 years old.\nLexapro is also used to treat anxiety in adults.\n','You should not use Lexapro if you also take pimozide or citalopram (Celexa).\nDo not use Lexapro within 14 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.\nSome young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nDo not give Lexapro to anyone under 12 years.\nBefore taking this medicine\nYou should not use Lexapro if you are allergic to escitalopram or citalopram (Celexa), or if:\nyou also take pimozide or citalopram.\nDo not use Lexapro within 14 days before or 14 days after you have used an MAO inhibitor. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.\nBe sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with escitalopram and cause a serious condition called serotonin syndrome.\nTo make sure Lexapro is safe for you, tell your doctor if you have ever had:\nliver or kidney disease;\nseizures;\nlow levels of sodium in your blood;\nheart disease, high blood pressure;\na stroke;\nbleeding problems;\nbipolar disorder (manic depression); or\ndrug addiction or suicidal thoughts.\nSome young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nLexapro is not approved for use by anyone younger than 12 years old.\nAsk your doctor about taking this medicine if you are pregnant. Taking an SSRI antidepressant during late pregnancy may cause serious medical complications in the baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking Lexapro without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of escitalopram on the baby.\nIf you are breastfeeding, tell your doctor if you notice drowsiness, agitation, feeding problems, or poor weight gain in the nursing baby.\nHow should I take Lexapro?\nTake Lexapro exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nTake the medicine at the same time each day, with or without food.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nIt may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nYour doctor will need to check your progress on a regular basis. A child taking Lexapro should be checked for height and weight gain.\nDo not stop using Lexapro suddenly, or you could have unpleasant withdrawal symptoms. Follow your doctor\'s instructions about tapering your dose.\nStore Lexapro at room temperature away from moisture and heat.\n','Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with Lexapro may cause you to bruise or bleed easily.\nAvoid alcohol.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(503,'lexette','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nDo not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Rinse with water if this medicine gets in your eyes or mouth.\nWash your hands before and after using halobetasol, unless you are using this medicine to treat the skin on your hands.\nShake the foam before each use.\nApply a thin layer of halobetasol topical to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.\nDo not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.\nIf you are treating the diaper area, do not use plastic pants or tight-fitting diapers.\nThis medicine is for short-term use only (2 weeks, or up to 8 weeks for psoriasis). Follow your doctor\'s dosing instructions very carefully.\nIf you use halobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.\nYou may need medical tests to be sure this medicine is not causing harmful effects.\nCall your doctor if your symptoms do not improve, or if they get worse.\nYou should not stop using halobetasol suddenly. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature away from moisture and heat. Do not freeze.\nKeep Lexette foam away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty canister.\n Detailed Lexette dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nApply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\nHigh doses or long-term use of  Lexette can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.\n','Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n Lexette drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nworsening of your skin condition;\nredness, warmth, swelling, oozing, or severe irritation of any treated skin;\nblurred vision, tunnel vision, eye pain, or seeing halos around lights;\nhigh blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or\npossible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.\nCommon side effects may include:\nburning, stinging, itching, or dryness of treated skin;\npain where the foam was applied;\nredness or crusting around your hair follicles;\nstretch marks;\nspider veins;\nheadache; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lexette side effects (more detail)\n','Halobetasol is a highly potent steroid that helps reduce inflammation in the body.\nLexette (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.\nLexette may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use halobetasol if you are allergic to it.\nTell your doctor if you have ever had:\nany type of skin infection;\na skin reaction to any steroid medicine;\nan adrenal gland disorder;\nliver disease; or\nif you plan to have surgery.\nSteroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.\nIt is not known whether  Lexette will harm an unborn baby. Tell your doctor if you are pregnant.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply halobetasol to your chest, avoid areas that may come into contact with the baby\'s mouth.\nLexette is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.\nChildren can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.\n','Avoid applying  Lexette to your face, scalp, underarms, or groin area.\nDo not use Lexette to treat any skin condition that has not been checked by your doctor.\nAvoid using other topical steroid medications on the areas you treat with halobetasol unless your doctor tells you to.\n'),(504,'lidex','This section provides information on the proper use of a number of products that contain fluocinonide.  It may not be specific to Lidex. Please read with care.\nIt is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.\nThis medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.\nThis medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.\nIf you are using the Vanos® cream:\nDo not use it on the face, groin, or underarms unless directed to do so by your doctor.\nDo not use it for more than 2 weeks unless your doctor tells you otherwise.\nTo use:\nWash your hands with soap and water before and after using this medicine.\nApply a thin layer of this medicine to the affected area of the skin. Rub it in gently.\nDo not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.\nIf the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.\nIf your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor topical dosage forms (cream, gel, ointment, or solution):\nFor redness, itching, and swelling of the skin:\nAdults—Apply to the affected area of the skin two to four times per day.\nChildren—Apply to the affected area of the skin two to four times per day.\nFor topical dosage form (cream):\nFor atopic dermatitis:\nAdults and children 12 years of age and older—Apply to the affected area of the skin once a day.\nChildren younger than 12 years of age—Use is not recommended.\nFor psoriasis:\nAdults and children 12 years of age and older—Apply to the affected area of the skin one to two times per day.\nChildren younger than 12 years of age—Use is not recommended.\nMissed dose\nIf you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Lidex dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nIncidence not known\nBlistering, burning, crusting, dryness, or flaking of the skin\nirritation\nitching, scaling, severe redness, soreness, or swelling of the skin\nredness and scaling around the mouth\nthinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)\nthinning, weakness, or wasting away of the skin\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nLess common\nFever\nheadache\nmuscle aches\nsore throat\nstuffy or runny nose\nunusual tiredness or weakness\nIncidence not known\nAcne or pimples\nburning and itching of the skin with pinhead-sized red blisters\nburning, itching, and pain in hairy areas, or pus at the root of the hair\nincreased hair growth on the forehead, back, arms, and legs\nlightening of normal skin color\nlightening of treated areas of dark skin\nreddish purple lines on the arms, face, legs, trunk, or groin\nsoftening of the skin\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Lidex side effects (more detail)\n','Fluocinonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid (cortisone-like medicine or steroid).\nThis medicine is available only with your doctor\'s prescription.\n','It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.\nIf your or your child\'s symptoms do not improve within a few days, or if they become worse, check with your doctor.\nUsing too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.\nStop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.\nDo not use cosmetics or other skin care products on the treated areas.\n',NULL),(505,'liletta',NULL,'Some drugs can affect your blood levels of levonorgestrel, which could make this form of birth control less effective. Tell your doctor about all your other medicines, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Liletta drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nGet emergency medical help if you have severe pain in your lower stomach or side. This could be a sign of a tubal pregnancy (a pregnancy that implants in the fallopian tube instead of the uterus). A tubal pregnancy is a medical emergency.\nThe levonorgestrel IUD may become embedded into the wall of the uterus, or may perforate (form a hole) in the uterus. If this occurs, the device may no longer prevent pregnancy, or it may move outside the uterus and cause scarring, infection, or damage to other organs. Your doctor may need to surgically remove the device.\nCall your doctor at once if you have:\nsevere cramps or pelvic pain, pain during sexual intercourse;\nextreme dizziness or light-headed feeling;\nsevere migraine headache;\nheavy or ongoing vaginal bleeding, vaginal sores, vaginal discharge that is watery, foul-smelling discharge, or otherwise unusual;\npale skin, weakness, easy bruising or bleeding, fever, chills, or other signs of infection;\njaundice (yellowing of the skin or eyes); or\nsudden numbness or weakness (especially on one side of the body), confusion, problems with vision, sensitivity to light.\nCommon side effects may include:\npelvic pain, vaginal itching or infection, missed or irregular menstrual periods, changes in bleeding patterns or flow (especially during the first 3 to 6 months);\ntemporary pain, bleeding, or dizziness during insertion of the IUD;\novarian cysts (pelvic pain that disappears within 3 months);\nstomach pain, nausea, vomiting, bloating;\nheadache, migraine, depression, mood changes;\nback pain, breast tenderness or pain;\nweight gain, acne, changes in hair growth, loss of interest in sex; or\npuffiness in your face, hands, ankles, or feet.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Liletta side effects (more detail)\n','Levonorgestrel is a female hormone that can cause changes in your cervix and uterus. Liletta is a T-shaped plastic intrauterine device (IUD) that is placed in the uterus where it slowly releases the hormone.\nLiletta used to prevent pregnancy for 3 to 6 years. You may use this IUD whether you have children or not. Mirena is also used to treat heavy menstrual bleeding in women who choose to use an intrauterine form of birth control.\nLevonorgestrel is a progestin and does not contain estrogen. Liletta should not be used as emergency birth control.\nLiletta may also be used for purposes not listed in this medication guide.\n','You should not use this device if you have abnormal vaginal bleeding, a pelvic infection, certain other problems with your uterus or cervix, or if you have breast or uterine cancer, liver disease or liver tumor, or a weak immune system.\nDo not use during pregnancy. Call your doctor if you think you might be pregnant.\n','Avoid having more than one sex partner. The IUD can increase your risk of developing a serious pelvic infection, which is often caused by sexually transmitted disease. Liletta will not protect you from sexually transmitted diseases, including HIV and AIDS. Using a condom is the only way to help protect yourself from these diseases.\nCall your doctor if your sex partner develops HIV or a sexually transmitted disease, or if you have any change in sexual relationships.\n'),(506,'linezolid','Administration\nAdminister orally or by IV infusion.\nWhen clinically appropriate, IV route may be switched to oral without dosage adjustment.\nAvoid large quantities of foods or beverages with high tyramine content during linezolid treatment. (See Monoamine Oxidase Inhibition under Cautions.)\nOral Administration\nAdminister orally without regard to meals.\nReconstitution\nReconstitute powder for oral suspension at time of dispensing by adding amount of water specified on bottle to provide a suspension containing 100 mg/5 mL. After tapping bottle gently to loosen the powder, add water in 2 portions and agitate well after each addition.\nPrior to administration of each dose, gently mix suspension by inverting bottle 3–5 times; do not shake.\nIV Administration\nFor solution and drug compatibility information, see Compatibility under Stability.\nSingle-use containers of linezolid injection for IV infusion should be administered without further dilution. Do not use the containers in series connections; do not introduce additives into the solution.\nRate of Administration\nAdminister by IV infusion over 30–120 minutes.\nDosage\nSafety and efficacy of >28 days of linezolid treatment not evaluated in controlled clinical trials.\nPediatric Patients\nGeneral Dosage for Neonates\nOral or IV\nNeonates: Manufacturer recommends 10 mg/kg every 12 hours initially in premature neonates <7 days of age; may consider 10 mg/kg every 8 hours in those with inadequate response. Manufacturer recommends 10 mg/kg every 8 hours in all neonates ≥7 days of age.\nNeonates ≤7 days of age: AAP recommends 10 mg/kg every 12 hours in those weighing ≤2 kg and 10 mg/kg every 8 hours in those weighing >2 kg.\nNeonates 8–28 days of age: AAP recommends 10 mg/kg every 8 hours, regardless of weight.\nGeneral Dosage for Infants and Children\nOral or IV\nManufacturer recommends 10 mg/kg every 8 hours in infants and children through 11 years of age and 600 mg every 12 hours in adolescents ≥12 years of age.\nAAP recommends 10 mg/kg 3 times daily in children <12 years of age and 600 mg twice daily in adolescents ≥12 years of age.\nRespiratory Tract Infections\nCommunity-acquired or Nosocomial Pneumonia\nChildren 7 days through 11 years of age: 10 mg/kg every 8 hours for 10–14 days.\nAdolescents ≥12 years of age: 600 mg every 12 hours for 10–14 days.\nCAP or healthcare-associated pneumonia caused by MRSA: IDSA recommends 7–21 days of treatment.\nSkin and Skin Structure Infections\nUncomplicated Skin and Skin Structure Infections\nChildren 7 days through 4 years of age: 10 mg/kg every 8 hours for 10–14 days.\nChildren 5 through 11 years of age: 10 mg/kg every 12 hours for 10–14 days.\nAdolescents ≥12 years of age: 600 mg every 12 hours for 10–14 days.\nComplicated Skin and Skin Structure Infections\nChildren 7 days through 11 years of age: 10 mg/kg every 8 hours for 10–14 days.\nAdolescents ≥12 years of age: 600 mg every 12 hours for 10–14 days.\nVancomycin-resistant Enterococcus faecium Infections\nOral or IV\nChildren 7 days through 11 years of age: 10 mg/kg every 8 hours for 14–28 days.\nAdolescents ≥12 years of age: 600 mg every 12 hours for 14–28 days.\nCNS Infections Caused by MRSA†\nOral or IV\n10 mg/kg (up to 600 mg) every 8 hours recommended by IDSA.\nAdults\nRespiratory Tract Infections\nCommunity-acquired or Nosocomial Pneumonia\n600 mg every 12 hours for 10–14 days.\nCAP or healthcare-associated pneumonia caused by MRSA: IDSA recommends 7–21 days of treatment.\nSkin and Skin Structure Infections\nUncomplicated Skin and Skin Structure Infections\n400 mg every 12 hours for 10–14 days.\nPurulent or nonpurulent cellulitis caused by MRSA: IDSA recommends 600 mg twice daily for 5–10 days; duration depends on clinical response.\nComplicated Skin and Skin Structure Infections\n600 mg every 12 hours for 10–14 days.\nComplicated infections caused by MRSA: IDSA recommends 7–14 days of treatment; duration depends on clinical response.\nVancomycin-resistant Enterococcus faecium Infections\nOral or IV\n600 mg every 12 hours for 14–28 days.\nCNS Infections Caused by MRSA†\nOral or IV\n600 mg every 12 hours recommended by IDSA.\nSpecial Populations\nHepatic Impairment\nMild to moderate hepatic impairment (Child-Pugh class A or B): Dosage adjustments not needed.\nSevere hepatic impairment: Pharmacokinetics not evaluated.\nRenal Impairment\nDosage adjustments not needed. Consider that linezolid metabolites may accumulate in patients with renal impairment; clinical importance unknown. (See Renal Impairment under Cautions.)\nHemodialysis patients: Administer linezolid doses after dialysis session.\nGeriatric Patients\nDosage adjustments not needed.\n Detailed Linezolid dosage information\n','Minimally metabolized; possibly by CYP isoenzymes.\nDoes not inhibit CYP1A2, 2C9, 2C19, 2D6, 2E1, or 3A4. Does not induce CYP isoenzymes.\nDrugs Affecting or Metabolized by Hepatic Microsomal Enzymes\nPotent inducers of hepatic enzymes: Possible reduced linezolid concentrations.\nSpecific Drugs\nDrug\nInteraction\nComments\nAminoglycosides\nGentamicin: No effect on pharmacokinetics of linezolid or gentamicin  \nGentamicin or streptomycin: In vitro evidence of additive or indifferent antibacterial effects\nAmpicillin\nIn vitro evidence of additive or indifferent antibacterial effects\nAntidiabetic agents, oral\nPotential for hypoglycemia\nDosage reduction of antidiabetic agent or discontinuance of linezolid or antidiabetic agent may be necessary\nAztreonam\nNo effect on pharmacokinetics of either drug  \nIn vitro evidence of additive or indifferent antibacterial effects\nCarbamazepine\nPossible decreased linezolid concentrations\nCarbapenems\nImipenem: In vitro evidence of additive or indifferent antibacterial effects\nInsulin\nPotential for hypoglycemia\nDosage reduction of insulin or discontinuance of linezolid or insulin may be necessary\nMAO inhibitors (isocarboxazid, phenelzine, selegiline, tranylcypromine)\nPotential pharmacologic interaction\nIncreased risk of CNS toxicity, including serotonin syndrome \nDo not use linezolid in patients who are receiving (or have received within the last 2 weeks) an MAO inhibitor (see Serotonergic Drugs under Specific Drugs)\nPhenobarbital\nPossible decreased linezolid concentrations\nPhenytoin\nEffect on phenytoin pharmacokinetics unlikely; possible decreased linezolid concentrations\nDosage adjustments not needed\nRifampin\nDecreased peak plasma concentration and AUC of linezolid\nIn vitro evidence of additive or indifferent antibacterial effects\nMechanism of the interaction and clinical importance unknown\nSerotonergic drugs (SSRIs, SNRIs, tricyclic antidepressants, amoxapine, bupropion, buspirone, maprotiline, meperidine, mirtazapine, nefazodone, trazodone, vilazodone)\nIncreased risk of serotonin syndrome, particularly with SSRIs and SNRIs;         unclear whether risk associated with other serotonergic drugs is comparable to that reported with SSRIs and SNRIs\nDo not use concurrently unless considered clinically appropriate and patient can be carefully monitored for manifestations of serotonin syndrome or NMS-like reactions \nIf urgent linezolid treatment necessary (e.g., life-threatening infections caused by MRSA or vancomycin-resistant E. faecium), promptly discontinue the serotonergic antidepressant and administer linezolid with close monitoring (see Serotonin Syndrome under Cautions)\nSerotonergic drug may be initiated or resumed 24 hours after last linezolid dose\nSympathomimetic agents\nReversible enhancement of pressor response may occur if linezolid used concomitantly with indirect-acting sympathomimetic agents (e.g., phenylpropanolamine, pseudoephedrine), vasopressor agents (e.g., epinephrine, norepinephrine), or dopaminergic agents (e.g., dopamine, dobutamine)\nDo not use concomitantly unless patient monitored for potential BP increases\nIf adrenergic agent (e.g., dopamine, epinephrine) initiated in patient receiving linezolid, use lower initial doses of the adrenergic agent and titrate dosage to achieve desired response\nVancomycin\nIn vitro evidence of additive or indifferent antibacterial effects\nVitamins (ascorbic acid, vitamin E)\nAscorbic acid or vitamin E: Concomitant use slightly increases linezolid AUC\nAscorbic acid or vitamin E: Dosage adjustments not needed\nWarfarin\nNo substantial effect on warfarin pharmacokinetics\nDosage adjustments not needed\n Linezolid drug interactions (more detail)\n',NULL,'Respiratory Tract Infections\nTreatment of community-acquired pneumonia (CAP), including infections associated with concurrent bacteremia, caused by susceptible Streptococcus pneumoniae.    \nTreatment of CAP caused by susceptible Staphylococcus aureus (methicillin-susceptible [oxacillin-susceptible] strains only).     Also recommended for treatment of CAP caused by methicillin-resistant S. aureus† (MRSA; also known as oxacillin-resistant S. aureus or ORSA).  \nTreatment of nosocomial pneumonia caused by susceptible S. aureus (including MRSA) or S. pneumoniae.   \nNot indicated for treatment of respiratory tract infections caused by gram-negative bacteria. It is imperative that an anti-infective active against gram-negative bacteria be used concomitantly if documented or presumed pathogens include gram-negative bacteria.\nFor information regarding treatment of pneumonia, including infections caused by MRSA, consult current IDSA clinical practice guidelines available at [Web].  \nSkin and Skin Structure Infections\nTreatment of uncomplicated skin and skin structure infections caused by susceptible S. aureus (methicillin-susceptible [oxacillin-susceptible] strains only) or S. pyogenes (group A β-hemolytic streptococci, GAS).  \nTreatment of complicated skin and skin structure infections (including diabetic foot infections), without concurrent osteomyelitis, caused by susceptible S. aureus (including MRSA), S. pyogenes, or S. agalactiae (group B streptococci, GBS).    \nNot evaluated for use in the treatment of decubitus ulcers. \nNot indicated for treatment of skin and skin structure infections caused by gram-negative bacteria. It is imperative that an anti-infective active against gram-negative bacteria be used concomitantly if the documented or presumed pathogens include gram-negative bacteria.\nFor information regarding treatment of skin and skin structure infections, including infections caused by MRSA, consult current IDSA clinical practice guidelines available at [Web].  \nVancomycin-resistant Enterococcus faecium Infections\nTreatment of infections caused by susceptible vancomycin-resistant Enterococcus faecium, including infections associated with concurrent bacteremia.  \nHas been used for treatment of native valve or prosthetic valve infective endocarditis† caused by vancomycin-resistant or multidrug-resistant E. faecium. AHA recommends that patients with infective endocarditis attributable to enterococci resistant to penicillins, aminoglycosides, and vancomycin be managed by a team of specialists in infectious disease, cardiology, cardiovascular surgery, clinical pharmacy, and, if necessary, pediatrics.\nFor information on diagnosis and management of infective endocarditis and its complications, including anti-infective treatment of enterococcal endocarditis, consult current AHA guidelines available at [Web].\nCNS Infections\nHas been recommended as an alternative to vancomycin for treatment of CNS infections caused by MRSA† (e.g., meningitis†, brain abscess†, subdural empyema†, spinal epidural abscess†). (See Pediatric Use under Cautions.)\nFor information regarding treatment of CNS infections caused by MRSA, consult current IDSA clinical practice guidelines available at [Web].\n',NULL,NULL),(507,'linzess','Usual Adult Dose for Irritable Bowel Syndrome:\n290 mcg orally once a day\nComments:\n-Patients should take this drug on an empty stomach, at least 30 minutes prior to the first meal of the day.\n-Capsules should be swallowed whole; patients should avoid breaking apart or chewing the capsules.\n-Patients with swallowing difficulties may open the capsules and administer orally (in applesauce or water) OR via nasogastric or gastrostomy tube (in water).\nUse: Treatment of irritable bowel syndrome with constipation (IBS-C)\nUsual Adult Dose for Constipation:\n145 mcg orally once a day\nComments:\n-Some patients may be given 72 mcg orally once a day based on individual characteristics and tolerability.\n-Patients should take this drug on an empty stomach, at least 30 minutes prior to the first meal of the day.\n-Capsules should be swallowed whole; patients should avoid breaking apart or chewing the capsules.\n-Patients with swallowing difficulties may open the capsules and administer orally (in applesauce or water) OR via nasogastric or gastrostomy tube (in water).\nUse: Treatment of chronic idiopathic constipation (CIC)\n Detailed Linzess dosage information\nWhat happens if I miss a dose?\nSkip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with linaclotide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Linzess drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Linzess: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using Linzess and call your doctor at once if you have:\nsevere or ongoing diarrhea; or\ndiarrhea with dizziness or a light-headed feeling (like you might pass out).\nCommon Linzess side effects may include:\ndiarrhea;\nstomach pain;\ngas; or\nbloating or full feeling in your stomach.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Linzess side effects (more detail)\n','Linzess (linaclotide) works by increasing the secretion of chloride and water in the intestines, which can soften stools and stimulate bowel movements.\nLinzess is a prescription medicine used used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in people who have had constipation as the main symptom.\nThe safety and effectiveness of Linzess has not been established in patients under 18 years of age.\n','You should not use Linzess if you have a blockage in your intestines.\nTake Linzess in the morning on an empty stomach, at least 30 minutes before your first meal. Do not crush, chew, break, or open a capsule. Swallow it whole.\nStop using this medicine and call your doctor at once if you have severe or ongoing diarrhea, severe stomach pain, or black, bloody, or tarry stools.\nBefore taking this medicine\nYou should not use Linzess if you are allergic to linaclotide, or if you have:\na blockage in your intestines (bowel obstruction).\nLinzess is not approved for use by anyone younger than 18 years old.\nLinzess should not be given to a child younger than 6 years old. Linaclotide can cause severe diarrhea and fatal dehydration in a child. Do not give this medicine to any child or teenager without the advice of a doctor.\nTell your doctor if you are pregnant or breastfeeding.\nHow should I take Linzess?\nTake Linzess exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nTake Linzess in the morning on an empty stomach, at least 30 minutes before your first meal.\nSwallow the capsule whole and do not crush, chew, break, or open it.\nIf you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce or bottled water. Swallow the mixture right away without chewing. Do not save it for later use.\nEven if you have taken this medicine with applesauce, wait at least 30 minutes before eating a full meal.\nIf needed, medicine from the Linzess capsule may be given through a nasogastric (NG) or gastronomy tube.\nCarefully follow instructions for mixing medicine from the capsule with applesauce or water, or giving the medicine through a feeding tube. Ask your doctor or pharmacist if you have any questions.\nIt may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nStore at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.\nKeep this medicine out of the reach of children. Linaclotide can be fatal to a child who accidentally swallows this medicine. Seek emergency medical attention if this happens.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(508,'liothyronine','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nOlder adults may be more sensitive to the effects of liothyronine, and doses are generally lower for people in this age group.\nIf you are switching to liothyronine from any other thyroid medicine, stop using the other medicine before you start taking liothyronine.\nLiothyronine doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.\nWhen given as part of a thyroid suppression test, you will need to take  liothyronine for several days in a row in preparation for the test. Tell your doctor if you miss any doses during this time.\nYour thyroid function will need to be tested often. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.\nIf you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using liothyronine.\nKeep using this medicine as directed, even if you feel well. You may need to take thyroid medication for the rest of your life.\nStore at room temperature away from moisture and heat.\n Detailed Liothyronine dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include headache, sweating, diarrhea, irregular menstrual periods, confusion, weakness, swelling in your hands or feet, fast heart rate, chest pain, feeling short of breath, fainting, or feeling nervous, restless, or irritable.\n','Some medicines can make liothyronine much less effective when taken at the same time. If you take any of the following medicines, take your liothyronine dose 4 hours before you take the other medicine.\ncholestyramine;\ncolesevelam;\ncolestipol; or\nsevelamer.\nTell your doctor about all your current medicines. Many drugs can affect liothyronine, especially:\ncancer medicine;\nbirth control pills or hormone replacement therapy;\ncough or cold medicine;\nan antidepressant;\nsteroid medicine;\nseizure medicine;\ninsulin or oral diabetes medicine; or\na blood thinner (warfarin, Coumadin, Jantoven).\nThis list is not complete and many other drugs may affect liothyronine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Liothyronine drug interactions (more detail)\nDoes Liothyronine interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using liothyronine and call your doctor if you have symptoms of thyroid toxicity, such as chest pain, fast or pounding heartbeats, feeling hot or nervous, or sweating more than usual.\nAlso call your doctor at once if you have:\nweak or shallow breathing;\nconfusion;\na feeling of being cold all the time;\nchanges in weight or appetite;\nchest pressure spreading to your jaw or shoulder;\na light-headed feeling, like you might pass out;\nsevere headaches, ringing in your ears, dizziness, vision problems, pain behind your eyes;\na seizure; or\n(in a child or teenager) pain, stiffness, and trouble moving the legs.\nCommon side effects may include:\ntrouble breathing;\nheadache;\ntremors, feeling nervous or irritable;\nmuscle weakness;\nincreased appetite;\ndiarrhea;\nirregular menstrual periods;\nweight loss;\nfeeling hot;\nrash; or\nsleep problems (insomnia).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Liothyronine side effects (more detail)\n','Liothyronine is a man-made form of a hormone that is normally produced by your thyroid gland to regulate the body\'s energy and metabolism. Liothyronine is given when the thyroid does not produce enough of this hormone on its own.\nLiothyronine treats hypothyroidism (low thyroid hormone). Liothyronine is also given as part of a medical test for thyroid disorders.\nLiothyronine is also used together with surgery and radioactive iodine therapy in people with thyroid cancer.\nLiothyronine should not be used to treat obesity or weight problems.\nLiothyronine may also be used for purposes not listed in this medication guide.\n','Liothyronine should not be used to treat obesity or weight problems.\nYou may not be able to use  liothyronine if you have an adrenal gland problem that is not controlled by treatment.\nStop taking liothyronine and call your doctor if you have symptoms of thyroid toxicity, such as chest pain, fast or pounding heartbeats, feeling hot or nervous, or sweating more than usual.\nBefore taking this medicine\nSince thyroid hormone occurs naturally in the body, almost anyone can take liothyronine. However, you may not be able to use this medicine if you have an adrenal gland problem that is not controlled by treatment.\nTell your doctor if you have ever had:\nproblems with your pituitary or adrenal gland;\nheart disease, angina (chest pain);\na bleeding or blood clotting disorder;\ndiabetes; or\nosteoporosis or low bone mineral density.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using this medicine if you are pregnant. Controlling your thyroid hormone levels is very important during pregnancy, and your dose needs may be different during each trimester.\n','Do not change brands or change to a generic product without first asking your doctor. Different brands of liothyronine may not work the same. If you get a prescription refill and your new pills look different, talk with your pharmacist or doctor.\n'),(509,'lipitor','Take Lipitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nLipitor is usually taken once a day, with or without food. Take the medicine at the same time each day.\nDo not break an Lipitor tablet before taking it, unless your doctor has told you to.\nYou may need to stop using this medicine for a short time if you have:\nuncontrolled seizures;\nan electrolyte imbalance (such as high or low potassium levels in your blood);\nseverely low blood pressure;\na severe infection or illness; or\nsurgery or a medical emergency.\nIt may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Lipitor is effective.\nLipitor is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture, heat, and light.\n Detailed Lipitor dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them. Tell your doctor about all your current medicines and any you start or stop using, especially:\nother cholesterol-lowering medication;\nantibiotic or antifungal medicine;\nbirth control pills;\nmedicine to prevent organ transplant rejection;\nheart medication; or\nmedicine to treat hepatitis C or HIV.\nThis list is not complete. Many other drugs may interact with atorvastatin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Lipitor drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Lipitor: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nIn rare cases, Lipitor can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.\nAlso call your doctor at once if you have:\nmuscle weakness in your hips, shoulders, neck, and back;\ntrouble lifting your arms, trouble climbing or standing;\nupper stomach pain, weakness, tired feeling, loss of appetite, dark urine, yellowing of the skin or eyes (signs of liver problems); or\nlittle or no urinating, swelling in your feet or ankles, feeling tired or short of breath (signs of kidney problems).\nCommon Lipitor side effects may include:\njoint pain;\nstuffy nose, sore throat;\ndiarrhea; or\npain in your arms or legs.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lipitor side effects (more detail)\n','Lipitor (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or \"statins.\"\nLipitor is used together with diet to lower blood levels of \"bad\" cholesterol (low-density lipoprotein, or LDL), to increase levels of \"good\" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).\nLipitor is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.\nLipitor is for use in adults and children who are at least 10 years old.\n','You should not take Lipitor if you are pregnant or breastfeeding, if you have liver disease, or if you have had an allergic reaction to Lipitor in the past.\nStop taking Lipitor and tell your doctor right away if you become pregnant.\nSerious drug interactions can occur when certain medicines are used together with Lipitor. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.\nAtorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.\nAvoid eating foods that are high in fat or cholesterol. Lipitor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Lipitor starts to work in about 2 weeks. Lipitor is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.\nBefore taking this medicine\nYou should not use Lipitor if you are allergic to atorvastatin, or if you have:\nliver disease; or\nif you are pregnant or breastfeeding.\nAtorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Lipitor and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.\nAtorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking Lipitor.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nliver problems;\nmuscle pain or weakness;\nkidney disease;\ndiabetes;\na thyroid disorder; or\nif you drink more than 2 alcoholic beverages daily.\nLipitor can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).\nAtorvastatin is not approved for use by anyone younger than 10 years old.\n','Avoid eating foods that are high in fat or cholesterol. Lipitor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.\nAvoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.\nGrapefruit and grapefruit juice may interact with atorvastatin and lead to unwanted side effects. Avoid drinking more than 1 liter of grapefruit juice per day while taking this medicine.\n'),(510,'liraglutide','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nDo not use Saxenda and Victoza together.\nLiraglutide is injected under the skin at any time of the day, with or without a meal. A healthcare provider may teach you how to properly use the medication by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.\nCall your doctor if you are sick with vomiting or diarrhea. You can easily become dehydrated while using liraglutide. This can lead to kidney failure.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nStoring unopened injection pens: Refrigerate and use until the expiration date.\nStoring after your first use: Store the pen in a refrigerator or at room temperature and use within 30 days.\nDo not freeze liraglutide, and throw away the medicine if it has become frozen.\nUse a needle only once and then place it in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n Detailed Liraglutide dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nSkip the missed dose and use the next regularly scheduled dose. Do not use two doses at one time.\nCall your doctor for instructions if you miss 3 or more doses of Saxenda.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Liraglutide can slow your digestion, and it may take longer for your body to absorb any medicines you take by mouth.\nTell your doctor if you also use insulin or oral diabetes medicine.\nOther drugs may affect liraglutide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Liraglutide drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; fast heartbeats; dizziness; trouble breathing or swallowing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nracing or pounding heartbeats;\nsudden changes in mood or behavior, suicidal thoughts;\ndehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;\nlow blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky;\ngallbladder or pancreas problems--sudden and severe pain in your upper stomach that may spread to your back, nausea, vomiting, fever, jaundice (yellowing of your skin or eyes); or\nsigns of a thyroid tumor--swelling or a lump in your neck, trouble swallowing, a hoarse voice, feeling short of breath.\nCommon side effects may include:\nlow blood sugar;\nnausea, vomiting, stomach discomfort, loss of appetite;\ndiarrhea, constipation;\nrash;\nheadache, dizziness; or\nfeeling tired.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Liraglutide side effects (more detail)\n','The Victoza brand of liraglutide is used together with diet and exercise to improve blood sugar control in adults and children at least 10 years old who have type 2 diabetes mellitus.\nVictoza is also used to help reduce the risk of serious heart problems such as heart attack or stroke in adults who have type 2 diabetes and heart disease. Victoza is not for treating type 1 diabetes.\nThe Saxenda brand of liraglutide is used together with diet and exercise to help people lose weight when they have certain health conditions. Saxenda is for use in adults with a body mass index (BMI) of 30 or higher, and for children at least 12 years old who weigh more than 132 pounds (60 kilograms).\nSaxenda is not for treating type 1 or type 2 diabetes. Saxenda is not a weight-loss medicine or appetite suppressant.\nLiraglutide may also be used for purposes not listed in this medication guide.\n','Do not use Saxenda and Victoza together.\nYou should not use liraglutide if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer.\nIn animal studies, liraglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses.\nCall your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.\nBefore taking this medicine\nYou should not use liraglutide if you are allergic to it, or if you have:\nmultiple endocrine neoplasia type 2 (tumors in your glands); or\na personal or family history of medullary thyroid carcinoma (a type of thyroid cancer).\nYou should not use Saxenda if you also use other medicines like liraglutide (albiglutide, dulaglutide, exenatide, Byetta, Bydureon, Tanzeum, Trulicity).\nTell your doctor if you have ever had:\nstomach problems causing slow digestion;\nkidney or liver disease;\nhigh triglycerides (a type of fat in the blood);\nheart problems;\nproblems with your pancreas or gallbladder; or\n(if you use Saxenda) depression or suicidal thoughts.\nIn animal studies, liraglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.\nDo not use Saxenda if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight. Stop using Saxenda and tell your doctor right away if you become pregnant.\nFollow your doctor\'s instructions about using Victoza if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nIt may not be safe to breastfeed while using liraglutide. Ask your doctor about any risk.\n','Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nDo not use Saxenda together with other weight loss products, diet pills, or appetite suppressants.\n'),(511,'lisinopril','Take lisinopril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nDrink plenty of water each day while you are taking this medicine.\nLisinopril can be taken with or without food.\nMeasure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.\nYour blood pressure will need to be checked often. Your kidney function and electrolytes may also need to be checked.\nCall your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking lisinopril.\nIf you need surgery, tell the surgeon ahead of time that you are using lisinopril.\nIf you have high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.\nStore at room temperature away from moisture and heat. Do not freeze the oral liquid.\n Detailed Lisinopril dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your current medicines and any you start or stop using, especially:\na diuretic or \"water pill\";\nlithium;\ngold injections to treat arthritis;\ninsulin or oral diabetes medicine;\na potassium supplement;\nmedicine to prevent organ transplant rejection - everolimus, sirolimus, tacrolimus, temsirolimus; or\nNSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nThis list is not complete. Other drugs may interact with lisinopril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Lisinopril drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to lisinopril: hives; severe stomach pain, difficult breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nfever, sore throat;\nhigh potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;\nkidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or\nliver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nCommon lisinopril side effects may include:\nheadache, dizziness;\ncough; or\nchest pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lisinopril side effects (more detail)\n','Lisinopril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.\nLisinopril is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old.\nLisinopril is also used to treat congestive heart failure in adults, or to improve survival after a heart attack.\n','Do not use lisinopril if you are pregnant. It could harm the unborn baby. Stop using this medicine and tell your doctor right away if you become pregnant.\nYou should not use this medicine if you have ever had angioedema. Do not take lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).\nIf you have diabetes, do not use lisinopril together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).\nYou may also need to avoid taking lisinopril with aliskiren if you have kidney disease.\nBefore taking this medicine\nYou should not use lisinopril if you are allergic to it, or if you:\nhave a history of angioedema;\nrecently took a heart medicine called sacubitril; or\nare allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.\nDo not take lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).\nIf you have diabetes, do not use lisinopril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).\nYou may also need to avoid taking lisinopril with aliskiren if you have kidney disease.\nTo make sure lisinopril is safe for you, tell your doctor if you have ever had:\nkidney disease (or if you are on dialysis);\nliver disease; or\nhigh levels of potassium in your blood.\nDo not use lisinopril if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. This medicine can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking lisinopril.\nIt is not known whether lisinopril passes into breast milk or if it could harm a nursing baby. You should not breastfeed while using lisinopril.\n','Drinking alcohol can further lower your blood pressure and may increase certain side effects of lisinopril.\nAvoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Lisinopril can decrease sweating and you may be more prone to heat stroke.\nDo not use potassium supplements or salt substitutes while taking this medicine, unless your doctor has told you to.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\n'),(512,'lithium','Usual Adult Dose for Mania:\nAcute Control:\n-Usual dose: 1800 mg/day\n-Extended release formulations: 900 mg orally in the morning and at nighttime\n-Regular release formulations: 600 mg orally 3 times a day, in the morning, afternoon, and nighttime\nLong-term Control:\n-Maintenance dose: 900 to 1200 mg/day\n-Extended release formulations: 600 mg orally in the morning and at nighttime\n-Regular release formulations: 300 mg orally 3 to 4 times a day\nUses:\n-Treatment of manic episodes of bipolar disorder\n-Maintenance treatment for individuals with bipolar disorder\nUsual Adult Dose for Bipolar Disorder:\nAcute Control:\n-Usual dose: 1800 mg/day\n-Extended release formulations: 900 mg orally in the morning and at nighttime\n-Regular release formulations: 600 mg orally 3 times a day, in the morning, afternoon, and nighttime\nLong-term Control:\n-Maintenance dose: 900 to 1200 mg/day\n-Extended release formulations: 600 mg orally in the morning and at nighttime\n-Regular release formulations: 300 mg orally 3 to 4 times a day\nUses:\n-Treatment of manic episodes of bipolar disorder\n-Maintenance treatment for individuals with bipolar disorder\nUsual Pediatric Dose for Mania:\n12 years and older:\nAcute Control:\n-Usual dose: 1800 mg/day\n-Extended release formulations: 900 mg orally in the morning and at nighttime\n-Regular release formulations: 600 mg orally 3 times a day, in the morning, afternoon, and nighttime\nLong-term Control:\n-Maintenance dose: 900 to 1200 mg/day\n-Extended release formulations: 600 mg orally in the morning and at nighttime\n-Regular release formulations: 300 mg orally 3 to 4 times a day\nUses:\n-Treatment of manic episodes of bipolar disorder\n-Maintenance treatment for individuals with bipolar disorder\nUsual Pediatric Dose for Bipolar Disorder:\n12 years and older:\nAcute Control:\n-Usual dose: 1800 mg/day\n-Extended release formulations: 900 mg orally in the morning and at nighttime\n-Regular release formulations: 600 mg orally 3 times a day, in the morning, afternoon, and nighttime\nLong-term Control:\n-Maintenance dose: 900 to 1200 mg/day\n-Extended release formulations: 600 mg orally in the morning and at nighttime\n-Regular release formulations: 300 mg orally 3 to 4 times a day\nUses:\n-Treatment of manic episodes of bipolar disorder\n-Maintenance treatment for individuals with bipolar disorder\n Detailed Lithium dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nStop taking lithium and seek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nEarly signs of toxicity include: vomiting, diarrhea, drowsiness, muscle weakness, or loss of coordination.\n','Tell your doctor about all your current medicines. Many drugs can affect lithium, especially:\nbuspirone;\nfentanyl;\nSt. John\'s wort;\ntramadol;\na \"triptan\" migraine headache medicine;\ntryptophan;\nan antidepressant or antipsychotic medication; or\na MAO inhibitor - isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nThis list is not complete and many other drugs may interact with lithium. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Lithium drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to lithium: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nToo much lithium in your body can cause death. Lithium toxicity can occur if you take only slightly more than a recommended dose.\nStop using this medicine and call your doctor right away if you have symptoms of lithium toxicity: muscle weakness, twitching, drowsiness, feeling light-headed, mood changes, blurred vision, ringing in your ears, irregular heartbeats, confusion, slurred speech, clumsiness, trouble breathing, or seizures.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nshortness of breath;\nfever, increased thirst or urination;\nweakness, dizziness or spinning sensation;\nmemory problems, hallucinations;\nproblems with balance or muscle movement;\nloss of bowel or bladder control;\na seizure (blackout or convulsions);\nlow sodium level - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady;\nthyroid problems - weight gain or loss, muscle pain, tremors, feeling hot or cold, changes in your skin or hair, sweating, feeling weak or tired, fast or pounding heartbeats, increased bowel movements, feeling anxious or agitated;\ndehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or\nincreased pressure inside the skull -severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nCommon lithium side effects may include:\ndizziness, drowsiness;\ntremors in your hands;\ntrouble walking;\ndry mouth, increased thirst or urination;\nnausea, vomiting, loss of appetite;\nrash; or\nblurred vision.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lithium side effects (more detail)\n','Lithium affects the flow of sodium through nerve and muscle cells in the body. Sodium affects excitation or mania.\nLithium a mood stabilizer that is a used to treat or control the manic episodes of bipolar disorder (manic depression). Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger.\nLithium also helps to prevent or lessen the intensity of manic episodes.\nLithium is for use in adults and children at least 7 years old.\n','Do not use lithium without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.\nLithium toxicity can cause death. Lithium is a medicine with a narrow range of safety and toxicity can occur if you take only slightly more than a recommended dose.\nStop using lithium and call your doctor right away if you have symptoms of lithium toxicity: muscle weakness, twitching, drowsiness, feeling light-headed, mood changes, blurred vision, ringing in your ears, irregular heartbeats, confusion, slurred speech, clumsiness. trouble breathing, or seizures.\nDo not crush, chew, or break an extended-release tablet. Swallow the pill whole. Drink extra fluids to keep from getting dehydrated while you are taking this medication.\nTell your doctor if you have been sweating excessively, or if you are sick with fever, vomiting, or diarrhea.\nAvoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor\'s instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.\nLithium can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.\nBefore taking this medicine\nYou should not use lithium if you are allergic to it.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nbreathing problems;\nheart disease;\nkidney disease;\na thyroid disorder;\nan abnormal electrocardiograph or ECG (sometimes called an EKG);\nfainting spells; or\na family member who died before age 45.\nSome medicines can interact with lithium and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.\nIt is not known whether lithium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nYou should not breast-feed while using this medicine.\nLithium is not approved for use by anyone younger than 7 years old.\nHow should I take lithium?\nTake lithium exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Never use lithium in larger amounts, or for longer than prescribed. Overdose can occur if you take only slightly more than a recommended dose.\nSwallow the tablet whole and do not crush, chew, or break it.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nCall your doctor if you are sick with a fever and vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking lithium, which may affect your dose needs. Do not change your dose or medication schedule without your doctor\'s advice.\nDrink extra fluids each day to prevent dehydration.\nIt may take up to 3 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not begin to improve after 1 week of treatment.\nYou may need frequent blood tests.\nIf you need surgery, tell the surgeon ahead of time that you are using this medicine.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\n','Avoid driving or hazardous activity until you know how lithium will affect you. Your reactions could be impaired.\nAvoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor\'s instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.\nDo not change the amount of salt you consume in your diet. Changing your salt intake could change the amount of lithium in your blood.\n'),(513,'lo-loestrin-fe','Take Loestrin 24 Fe exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nEach blister card (28 tablets) of Loestrin 24 Fe contains 24 white, round (active) tablets with 1 mg norethindrone acetate and 20 mcg ethinyl estradiol and 4 brown (placebo) tablets containing 75 mg ferrous fumarate. The ferrous fumarate tablets do not serve any therapeutic purpose.\nTake your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms with spermicide, when you first start using this medication. Follow your doctor\'s instructions.\nTake one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You may get pregnant if you do not take one pill daily. Get your prescription refilled before you run out of pills completely.\nUse a back-up birth control if you are sick with severe vomiting or diarrhea.\nYou may have breakthrough bleeding, especially during the first 3 months. Tell your doctor if this bleeding continues or is very heavy.\nIf you need major surgery with long-term bed rest, you may need to stop using Loestrin 24 Fe for a short time. Any doctor or surgeon who treats you should know that you are using birth control pills.\nWhile taking Loestrin 24 Fe, you will need to visit your doctor regularly.\nStore Loestrin 24 Fe at room temperature away from moisture and heat.\n Detailed Lo Loestrin Fe dosage information\nWhat happens if I miss a dose?\nFollow the patient instructions provided with your medicine. Missing a pill increases your risk of becoming pregnant.\nIf you miss 1 active pill, take 2 pills on the day you remember. Then take 1 pill per day for the rest of the pack.\nIf you miss 2 active pills in a row in Week 1 or 2, take 2 pills per day for 2 days in a row. Then take 1 pill per day for the rest of the pack. Use back-up birth control for at least 7 days following the missed pills.\nIf you miss 2 active pills in a row in Week 3, throw out the rest of the pack and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.\nIf you miss 3 active pills in a row in Week 1, 2, or 3, throw out the rest of the pack and start a new pack on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.\nIf you miss 2 or more active pills, you may not have a period during the month. If you miss a period for 2 months in a row, call your doctor because you might be pregnant.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may cause nausea or vaginal bleeding.\n','Other drugs may interact with ethinyl estradiol and norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Some drugs can make Loestrin 24 Fe less effective, which may result in pregnancy. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Lo Loestrin Fe drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Loestrin 24 Fe: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using this medicine and call your doctor at once if you have:\nsigns of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;\nsigns of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;\nheart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;\nliver problems - loss of appetite, upper stomach pain, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nincreased blood pressure - severe headache, blurred vision, pounding in your neck or ears;\nswelling in your hands, ankles, or feet;\na change in the pattern or severity of migraine headaches;\na breast lump; or\nsymptoms of depression - sleep problems, weakness, tired feeling, mood changes.\nCommon Loestrin 24 Fe side effects may include:\nnausea, vomiting;\nbreast tenderness;\nbreakthrough bleeding;\nheadache; or\nproblems with contact lenses.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lo Loestrin Fe side effects (more detail)\nBefore taking this medicine\nTaking Loestrin 24 Fe can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking birth control pills. Your risk is also high when you restart birth control pills after not taking them for 4 weeks or longer.\nSmoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not take Loestrin 24 Fe if you smoke and are over 35 years old.\nDo not use if you are pregnant. Stop using Loestrin 24 Fe and tell your doctor right away if you become pregnant, or if you miss 2 menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking Loestrin 24 Fe.\nYou should not take Loestrin 24 Fe if you have:\nuntreated or uncontrolled high blood pressure;\nheart disease (chest pain, coronary artery disease, history of heart attack, stroke, or blood clot);\nan increased risk of having blood clots due to a heart problem or a hereditary blood disorder;\ncirculation problems (especially if caused by diabetes);\na history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;\nunusual vaginal bleeding that has not been checked by a doctor;\nliver disease or liver cancer;\nsevere migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;\na history of jaundice caused by pregnancy or birth control pills;\nif you smoke and are over 35 years old; or\nif you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir (Technivie).\nTo make sure Loestrin 24 Fe are safe for you, tell your doctor if you have ever had:\nheart problems, high blood pressure, or if you are prone to having blood clots;\nhigh cholesterol or triglycerides, or if you are overweight;\ndepression;\na seizure or migraine headache;\ndiabetes, gallbladder disease, underactive thyroid;\nliver or kidney disease;\nirregular menstrual cycles; or\nfibrocystic breast disease, lumps, nodules, or an abnormal mammogram.\nThe hormones in Loestrin 24 Fe can pass into breast milk and may harm a nursing baby. Birth control pills may also slow breast milk production. Do not use if you are breast feeding a baby.\n','Loestrin 24 Fe (ethinyl estradiol and norethindrone, and ferrous fumarate) is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.\nLoestrin 24 Fe is used as contraception to prevent pregnancy.\nLoestrin 24 Fe may also be used for purposes not listed in this medication guide.\n','Do not use Loestrin 24 Fe if you are pregnant or if you have recently had a baby.\nYou should not use Loestrin 24 Fe if you have: uncontrolled high blood pressure, heart disease, coronary artery disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you also take certain hepatitis C medication, if you have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, jaundice caused by pregnancy or birth control pills, or cancer of the breast, uterus/cervix, or vagina.\nTaking Loestrin 24 Fe can increase your risk of blood clots, stroke, or heart attack.\nSmoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take Loestrin 24 Fe if you smoke and are over 35 years old.\n','Do not smoke while taking Loestrin 24 Fe, especially if you are older than 35 years of age.\nLoestrin 24 Fe will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.\n'),(514,'lokelma','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nYou will need medical tests to help your doctor determine how long to treat you with Lokelma.\nStore at room temperature away from moisture and heat.\nLokelma can make it harder for your body to absorb other medicines you take by mouth. If you take any other medicines, take them 2 hours before or 2 hours after you take this medicine.\n Detailed Lokelma dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may affect Lokelma, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Lokelma drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\n Lokelma contains sodium and may cause swelling or rapid weight gain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lokelma side effects (more detail)\n','Lokelma is used to treat hyperkalemia (high levels of potassium in the blood) in adults.\nLokelma works directly in the intestines and is not absorbed into your bloodstream.\nLokelma may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nTell your doctor if you have ever had:\nslow digestion;\na bowel obstruction or severe constipation;\nheart problems; or\nif you are on a low-salt diet.\nBecause  Lokelma is not absorbed into the bloodstream, it is not expected to be harmful during pregnancy or while nursing a baby. Tell your doctor if you are pregnant or breast-feeding.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(515,'lomotil','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nDrink plenty of liquids to keep from getting dehydrated while you have diarrhea. Your doctor may recommend an electrolyte supplement such as Gatorade or Pedialyte. Carefully follow all care instructions.\nIt may take up to 48 hours before your symptoms improve. Keep using the medication as directed. Call your doctor if you still have diarrhea after 10 days, or if you have a fever.\nStore at room temperature away from moisture and heat.\nKeep  Lomotil where a child cannot reach it. An overdose of atropine and diphenoxylate can be fatal to a child.\n Detailed Lomotil dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of  Lomotil can cause breathing problems and may result in death or permanent brain damage.\nEarly overdose symptoms include weakness, blurred vision, slurred speech, feeling hot, fast heartbeats, slowed breathing, fainting, seizure, or coma. Report any early overdose symptoms to your doctor as soon as possible.\n','Using  Lomotil with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, cold or allergy medicine, or medicine for anxiety, depression, or seizures.\nTell your doctor about all your other medicines. Some may affect Lomotil, especially:\nmedicine to treat Parkinson\'s disease;\nmedicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;\nbladder or urinary medicines;\na bronchodilator; or\nan MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nThis list is not complete. Other drugs may affect Lomotil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Lomotil drug interactions (more detail)\nDoes Lomotil interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome side effects may occur up to 30 hours after you take this medicine.\nStop using this medicine and call your doctor at once if you have:\nsevere constipation, stomach pain or bloating;\nongoing or worsening diarrhea;\ndiarrhea that is watery or bloody;\nsevere pain in your upper stomach spreading to your back;\nfever, flushing (warmth, redness, or tingly feeling);\nhallucinations, seizure;\nrapid breathing, weak or shallow breathing;\nfast heart rate; or\ndehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.\nCommon side effects may include:\ndrowsiness, dizziness, feeling restless;\nheadache;\nnumbness in your hands or feet;\ndepression, not feeling well;\nconfusion, feelings of extreme happiness;\nred or swollen gums;\ndry mouth, nose, or throat;\nnausea, vomiting, upset stomach, loss of appetite; or\nskin rash, dryness, or itching.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Lomotil side effects (more detail)\n','Atropine affects the body in many different ways, such as reducing spasms in the bladder, stomach, and intestines.\nDiphenoxylate is an antidiarrheal medication.\nLomotil is a combination medicine used to treat diarrhea in adults and children who are at least 13 years old.\nLomotil may also be used for purposes not listed in this medication guide.\n','Do not use  Lomotil if you have diarrhea that is caused by bacteria or by taking an antibiotic. You should not use Lomotil if you have a bile duct disorder causing jaundice (yellowing of your skin or eyes).\nKeep this medicine where a child cannot reach it. An overdose can be fatal to a child.\nBefore taking this medicine\nYou should not use this medicine if you are allergic to atropine or diphenoxylate, or if you have:\nobstructive jaundice (a bile duct disorder that may cause yellowing of your skin or eyes);\ndiarrhea that is caused by bacteria; or\ndiarrhea caused by using antibiotic medication.\nLomotil is not approved for use by anyone younger than 6 years old. This medicine has not been proven safe or effective in children younger than 13 years old.\nTell your doctor if you have ever had:\na blockage in your intestines;\nulcerative colitis;\nasthma or other breathing problems;\nglaucoma;\nurination problems;\nliver or kidney disease;\nDown\'s syndrome; or\nif you are dehydrated.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.\nIt may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.\n','Avoid driving or hazardous activity until you know how  Lomotil will affect you. Your reactions could be impaired.\nAvoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor\'s instructions about the type and amount of liquids you should drink.\nDrinking alcohol with this medicine can cause side effects.\n'),(516,'loperamide','Use exactly as directed on the label, or as prescribed by your doctor.\nLoperamide is safe when used as directed. TAKING TOO MUCH LOPERAMIDE CAN CAUSE SERIOUS HEART PROBLEMS OR DEATH.\nAlways follow directions on the medicine label about giving loperamide to a child. A safe dose of loperamide is different for an adult than for a child. Doses in children are based on the child\'s age.\nTake loperamide with a full glass of water. Diarrhea can cause your body to lose fluids and electrolytes. Drink plenty of liquids to keep from getting dehydrated.\nThe loperamide chewable tablet must be chewed before swallowing.\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nNot all liquid forms of loperamide are the same strengths. Carefully follow all dosing instructions for the medicine you are using.\nStore at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.\nStop taking loperamide and call your doctor if you still have diarrhea after 2 days of treatment, or if you also have stomach bloating.\n Detailed Loperamide dosage information\nWhat happens if I miss a dose?\nSince loperamide is used when needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using  loperamide.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of loperamide can be fatal.\nOverdose symptoms may include fast or irregular heartbeats, or fainting. A person caring for you should seek emergency medical attention if you pass out and are hard to wake up.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take. Ask a doctor or pharmacist about safely using medications together.\nLoperamide can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, heart problems, depression, mental illness, cancer, malaria, or HIV.\nMany drugs can affect loperamide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Loperamide drug interactions (more detail)\nDoes Loperamide interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop taking loperamide and call your doctor at once if you have:\ndiarrhea that is watery or bloody;\nstomach pain or bloating;\nongoing or worsening diarrhea; or\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out).\nCommon side effects may include:\nconstipation;\ndizziness, drowsiness;\nnausea; or\nstomach cramps.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Loperamide side effects (more detail)\n','Loperamide is used to treat diarrhea.\nLoperamide is also used to reduce the amount of stool in people who have an ileostomy (re-routing of the bowel through a surgical opening in the stomach).\nLoperamide may also be used for purposes not listed in this medication guide.\n','You should not use loperamide if you have ulcerative colitis, bloody or tarry stools, diarrhea with a high fever, or diarrhea caused by antibiotic medication.\nLoperamide is safe when used as directed. TAKING TOO MUCH LOPERAMIDE CAN CAUSE SERIOUS HEART PROBLEMS OR DEATH.\nSerious heart problems may also happen if you take loperamide with other medicines. Ask a doctor or pharmacist about safely using medications together.\nDo not give loperamide to a child younger than 2 years old.\nBefore taking this medicine\nYou should not use loperamide if you are allergic to it, or if you have:\nstomach pain without diarrhea;\ndiarrhea with a high fever;\nulcerative colitis;\ndiarrhea that is caused by a bacterial infection; or\nstools that are bloody, black, or tarry.\nAsk your doctor before using loperamide to treat diarrhea caused by taking an antibiotic (Clostridium difficile).\nDo not give loperamide to a child younger than 2 years old. Do not give  loperamide to an older child or teenager without a doctor\'s advice.\nAsk a doctor or pharmacist if it is safe for you to take loperamide if you have:\na fever;\nmucus in your stools;\nliver disease; or\na heart rhythm disorder.\nAsk a doctor before using this medicine if you are pregnant.\nYou should not breast-feed while you are using loperamide.\n','Avoid drinking tonic water. It can interact with loperamide and may cause serious heart problems.\nAvoid becoming dehydrated by drinking plenty of fluids. Avoid vigorous exercise or exposure to hot weather if you are dehydrated.\nAvoid driving or hazardous activity until you know how  loperamide will affect you. Your reactions could be impaired.\n'),(517,'lopressor','This section provides information on the proper use of a number of products that contain metoprolol.  It may not be specific to Lopressor. Please read with care.\nTake this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.\nIn addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet.\nMany patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.\nRemember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.\nSwallow the extended-release capsule and tablet whole. Do not crush, break, or chew them.\nIf you cannot swallow the extended-release capsule:\nYou may open it and sprinkle the contents over a small amount (teaspoonful) of soft food (including applesauce, pudding, or yogurt). Swallow the mixture within 60 minutes. Do not store for later use.\nYou may also use a nasogastric tube to give the medicine. Mix the contents of the opened capsule with water into a syringe. Gently shake the mixture for about 10 seconds, then flush it through the tube. Rinse the tube with water until all of the medicine is washed out.\nTake the tablet or extended-release tablet with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor acute heart attack or heart failure:\nFor oral dosage form (extended-release capsules):\nAdults—At first, 25 milligrams (mg) once a day for 2 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day.\nChildren—Use and dose must be determined by your doctor.\nFor oral dosage form (extended-release tablets):\nAdults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed.\nChildren—Use and dose must be determined by your doctor.\nFor oral dosage form (tablets):\nAdults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg 2 times a day. The medicine will be started in the hospital.\nChildren—Use and dose must be determined by your doctor.\nFor chest pain:\nFor oral dosage form (extended-release capsules):\nAdults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.\nChildren—Use and dose must be determined by your doctor.\nFor oral dosage form (extended-release tablets):\nAdults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.\nChildren—Use and dose must be determined by your doctor.\nFor oral dosage form (tablets):\nAdults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.\nChildren—Use and dose must be determined by your doctor.\nFor high blood pressure:\nFor oral dosage form (extended-release capsules):\nAdults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.\nChildren 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight once a day. The first dose should not be more than 50 mg once a day. Your doctor may adjust your dose as needed.\nChildren younger than 6 years of age—Use and dose must be determined by your doctor.\nFor oral dosage form (extended-release tablets):\nAdults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.\nChildren 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day.\nChildren younger than 6 years of age—Use and dose must be determined by your doctor.\nFor oral dosage form (tablets):\nAdults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day.\nChildren—Use and dose must be determined by your doctor. .\nMissed dose\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Lopressor dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nMore common\nBlurred vision\nchest pain or discomfort\nconfusion\ndizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position\nslow or irregular heartbeat\nsweating\nunusual tiredness or weakness\nLess common\nBloating or swelling of the face, arms, hands, lower legs, or feet\ncough\ndecreased urine output\ndifficult or labored breathing\ndifficulty with speaking\ndilated neck veins\ndisturbed color perception\ndouble vision\nextreme tiredness or weakness\nfast, pounding, or racing heartbeat or pulse\nhalos around lights\nheadache\ninability to move the arms, legs, or facial muscles\ninability to speak\nirregular breathing\nloss of vision\nnight blindness\nnoisy breathing\noverbright appearance of lights\npain, tension, and weakness upon walking that subsides during periods of rest\npaleness or cold feeling in the fingertips and toes\nrapid weight gain\nseeing, hearing, or feeling things that are not there\nshort-term memory loss\nslow speech\nswelling of the face, fingers, feet, or lower legs\ntightness in the chest\ntingling of the hands or feet\ntingling or pain in the fingers or toes when exposed to cold temperatures\ntroubled breathing\ntunnel vision\nunusual weight gain or loss\nRare\nBluish color of the skin of the fingers or toes\nchills\nclay-colored stools\ncontinuing loss of appetite\ncontinuing or severe abdominal or stomach pain\ncontinuing or severe nausea and vomiting\ndark urine\ndifficulty with moving\nfever\ngeneral tiredness and weakness\nhoarseness\nincreased frequency of urination\nitching skin\nlight-colored stools\nlower back or side pain\nmuscle pain or stiffness\nnumbness of the fingers or toes\npain, swelling, or redness in the joints\nrash\nsore throat\nsores, ulcers, or white spots on the lips or in the mouth\nunpleasant breath odor\nunusual bleeding or bruising\nupper right abdominal or stomach pain\nvomiting of blood\nweakness\nyellow eyes and skin\nIncidence not known\nBlack, tarry stools\nbleeding gums\nblood in the urine or stools\nburning, crawling, itching, numbness, prickling, \"pins and needles\", or tingling feelings\ncool, sweaty skin\npinpoint red spots on the skin\nGet emergency help immediately if any of the following symptoms of overdose occur:\nSymptoms of overdose\nBluish color of the fingernails, lips, skin, palms, or nail beds\nchange in consciousness\nloss of consciousness\nno blood pressure or pulse\nstopping of the heart\nvery drowsy or sleepy\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nLess common\nBelching\nbloated feeling\ndecreased interest in sexual intercourse\ndifficulty having a bowel movement\ndiscouragement\ndry mouth\nexcess air or gas in stomach or bowels\nfeeling of constant movement of self or surroundings\nfeeling of fullness\nfeeling of indigestion\nfeeling sad or empty\ninability to have or keep an erection\nirritability\nloss in sexual ability, desire, drive, or performance\nloss of interest or pleasure\nnightmares\npain in the chest below the breastbone\npassing gas\nredness or other discoloration of the skin\nrunny nose\nsensation of spinning\nsneezing\nstuffy nose\ntiredness\ntrouble concentrating\ntrouble sleeping\nRare\nBone pain\ncontinuing ringing or buzzing or other unexplained noise in the ears\ndry eyes\nhair loss or thinning of the hair\nhearing loss\nincreased sensitivity of the skin to sunlight\npain in the penis on erection\nsevere sunburn\nIncidence not known\nChange in taste or bad, unusual, or unpleasant (after) taste\nfear or nervousness\nhives or welts\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Lopressor side effects (more detail)\n','Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. A lower blood pressure can reduce the risk of strokes and heart attacks.\nMetoprolol is also used to treat severe chest pain (angina) and lowers the risk of repeated heart attacks. It is given to people who have already had a heart attack. In addition, metoprolol is used to treat patients with heart failure.\nThis medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.\nThis medicine is available only with your doctor\'s prescription.\n','It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.\nMetoprolol may worsen the symptoms of heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing or heartbeat, shortness of breath, swelling of the face, fingers, feet, or lower legs, or weight gain.\nDo not suddenly stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous.\nThis medicine may cause changes in blood sugar levels. Also, this medicine may cover up the symptoms of low blood sugar, such as a rapid pulse rate. Check with your doctor if you notice a change in your normal symptoms or a change in the results of your blood or urine sugar tests.\nMake sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery.\nThis medicine may cause some people to become less alert than they are normally. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.\nDizziness, lightheadedness, or even fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.\nAvoid drinking alcohol while you are using the extended-release capsules.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may increase your blood pressure.\n',NULL),(518,'loratadine','Usual Adult Dose of Loratadine for Allergic Rhinitis:\n10 mg orally once a day\nUsual Adult Dose for Urticaria:\n10 mg orally once a day\nUsual Pediatric Dose for Allergic Rhinitis:\n2 to 5 years: 5 mg orally once a day (syrup)\n6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)\nUsual Pediatric Dose for Urticaria:\n2 to 5 years: 5 mg orally once a day (syrup)\n6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)\n Detailed Loratadine dosage information\n','Other drugs may interact with loratadine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Loratadine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to loratadine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using loratadine and call your doctor at once if you have:\nfast or uneven heart rate;\nsevere headache; or\na light-headed feeling, like you might pass out;\nCommon loratadine side effects may include:\nheadache;\nfeeling tired or drowsy;\nstomach pain, vomiting;\ndry mouth; or\nfeeling nervous or hyperactive.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Loratadine side effects (more detail)\n','Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.\nLoratadine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.\nLoratadine is also used to treat skin hives and itching in people with chronic skin reactions.\n','You should not take this medication if you are allergic to loratadine or to desloratadine (Clarinex).\nFollow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nSome chewable dosage forms of loratadine may contain phenylalanine. Talk to your doctor before using these forms of loratadine if you have phenylketonuria (PKU).\nAsk a doctor or pharmacist before taking this medicine if you have liver or kidney disease.\nBefore taking this medicine\nYou should not take this medicine if you are allergic to loratadine or to desloratadine (Clarinex).\nAsk a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:\nasthma;\nkidney disease; or\nliver disease.\nLoratadine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nLoratadine can pass into breast milk, but is considered compatible with breastfeeding. Tell your doctor if you are breast-feeding a baby.\nSome forms of loratadine may contain phenylalanine. Talk to your doctor before taking loratadine if you have phenylketonuria (PKU).\nHow should I take loratadine?\nUse loratadine exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold or allergy medicine is usually taken only for a short time until your symptoms clear up.\nDo not give this medicine to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.\nLoratadine is usually taken once per day. Follow your doctor\'s instructions.\nDo not crush, chew, or break the regular tablet. Swallow the pill whole.\nMeasure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.\nThe chewable tablet must be chewed before you swallow it.\nTo take the orally disintegrating tablet (Claritin RediTab, Alavert):\nKeep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil. Do not push a tablet through the foil or you may damage the tablet.\nUse dry hands to remove the tablet and place it in your mouth.\nDo not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. If desired, you may drink liquid to help swallow the dissolved tablet.\nCall your doctor if your symptoms do not improve, or if they get worse.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include headache, drowsiness, and fast or pounding heartbeat.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),