Get emergency medical help if you have signs of an allergic reaction to hydrochlorothiazide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
a light-headed feeling;
eye pain, vision problems;
jaundice (yellowing of the skin or eyes);
pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum);
shortness of breath, wheezing, cough with foamy mucus, chest pain;
dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or
signs of an electrolyte imbalance - increased thirst or urination, confusion, vomiting, constipation, muscle pain, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling.
Common hydrochlorothiazide side effects may include:
weakness;
feeling like you might pass out;
severe pain in your upper stomach spreading to your back, nausea and vomiting;
fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
electrolyte imbalance.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Hydrochlorothiazide side effects (more detail)
