Using Trokendi XR with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression.
Tell your doctor about all your other medicines, especially:
zonisamide;
birth control pills;
divalproex, valproic acid; or
other glaucoma medications, including eye drops.
This list is not complete. Other drugs may interact with topiramate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Trokendi XR drug interactions (more detail)
