Why do I need pharmacogenetic testing?
Your health care provider may order these tests before you start a certain medicine, or if you are taking a medicine that is not working and/or causing bad side effects.
Pharmacogenetic tests are only available for a limited number of medicines. Below are some of the medicines and genes that can be tested. (Gene names are usually given in letters and numbers.)
Medicine
Genes
Warfarin: a blood thinner
CYP2C9 and VKORC1
Plavix, a blood thinner
CYP2C19
Antidepressants, epilepsy medicines
CYP2D6, CYPD6 CYP2C9, CYP1A2, SLC6A4, HTR2A/C
Tamoxifen, a treatment for breast cancer
CYPD6
Antipsychotics
DRD3, CYP2D6, CYP2C19, CYP1A2
Treatments for attention deficit disorder
D4D4
Carbamazepine, a treatment for epilepsy
HLA-B*1502
Abacavir, a treatment for HIV
HLA-B*5701
Opioids
OPRM1
Statins, medicines that treat high cholesterol
SLCO1B1
Treatments for childhood leukemia and certain autoimmune disorders
TMPT
