When using Otezla your weight should be monitored regularly. Any unexplained or significant weight loss should be reported to your health care provider.
Contact your healthcare provider if you experience severe diarrhea, nausea, or vomiting.
Some people have thoughts about suicide while taking Otezla. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Before taking this medicine
You should not use Otezla if you are allergic to apremilast.
To make sure Otezla is safe for you, tell your doctor if you have ever had:
kidney disease; or
depression or suicidal thoughts or actions.
Some people have thoughts about suicide while taking Otezla. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Apremilast may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of apremilast on the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Otezla is not approved for use by anyone younger than 18 years old.
How should I take Otezla?
Take Otezla exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
You may take Otezla with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
Keep track of your body weight while you are taking this medicine, and tell your doctor about any major weight loss.
Store at room temperature away from moisture and heat.
