Get emergency medical help if you have signs of an allergic reaction to metoclopramide: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking metoclopramide and call your doctor at once if you have any of these SIGNS OF A SERIOUS MOVEMENT DISORDER, which may occur within the first 2 days of treatment:
tremors or shaking in your arms or legs;
uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or
any new or unusual muscle movements you cannot control.
Call your doctor at once if you have:
confusion, depression, thoughts of suicide or hurting yourself;
slow or jerky muscle movements, problems with balance or walking;
mask-like appearance in your face;
a seizure;
anxiety, agitation, jittery feeling, trouble staying still, trouble sleeping;
swelling, feeling short of breath, rapid weight gain; or
severe nervous system reactionvery stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.
Common metoclopramide side effects may include:
feeling restless;
feeling drowsy or tired;
lack of energy;
nausea, vomiting;
headache, confusion; or
sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Metoclopramide side effects (more detail)
