(372,'hyoscyamine','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nAlways follow directions on the medicine label about giving  hyoscyamine to a child.\nSwallow an extended-release tablet whole and do not crush, chew, or break it.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nRemove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve. Swallow several times as the tablet dissolves. You may drink water after the pill has completely dissolved.\nStore at room temperature away from moisture and heat.\n Detailed Hyoscyamine dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include headache, dizziness, dry mouth, trouble swallowing, nausea, vomiting, blurred vision, hot dry skin, and feeling restless or nervous.\n','Tell your doctor about all your other medicines, especially:\nan antidepressant;\nmedicine to treat mental illness;\ncold or allergy medicine (Benadryl and others);\nmedicine to treat or prevent nausea and vomiting; or\nan MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nThis list is not complete. Other drugs may affect hyoscyamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Hyoscyamine drug interactions (more detail)\nDoes Hyoscyamine interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using hyoscyamine and call your doctor at once if you have:\nanxiety, confusion, hallucinations, unusual thoughts or behavior;\nweakness, memory problems;\nslurred speech;\nproblems with balance or muscle movement;\ndiarrhea; o\npounding heartbeats or fluttering in your chest.\nCommon side effects may include:\ndizziness, drowsiness, feeling weak or tired;\ndecreased sweating, decreased urination;\nblurred vision;\nrash;\ndry mouth, decreased sense of taste;\nstomach pain, nausea, vomiting, bloating;\ndiarrhea, constipation;\nheadache;\nsleep problems (insomnia); or\nimpotence, loss of interest in sex, or trouble having an orgasm.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Hyoscyamine side effects (more detail)\n','Hyoscyamine is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome. It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid.\nHyoscyamine is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson\'s disease.\nHyoscyamine is also used as a drying agent to control excessive salivation, runny nose, or excessive sweating.\nHyoscyamine may also be used for purposes not listed in this medication guide.\n','You should not use  hyoscyamine if you have urination problems, a stomach or bowel obstruction, severe ulcerative colitis, glaucoma, or myasthenia gravis.\nBefore taking this medicine\nYou should not use hyoscyamine if you are allergic to it, or if you have:\na bladder obstruction or other urination problems;\nan enlarged prostate;\na stomach or bowel obstruction (including paralytic ileus);\nsevere ulcerative colitis, or toxic megacolon;\nglaucoma; or\nmyasthenia gravis.\nHyoscyamine is not approved for use by anyone younger than 2 years old.\nTell your doctor if you have ever had:\nheart problems;\nhigh blood pressure;\nkidney disease;\na colostomy or ileostomy;\na thyroid disorder; or\nhiatal hernia with GERD (gastroesophageal reflux disease).\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.\n','Avoid taking antacids at the same time you take hyoscyamine. Antacids can make it harder for your body to absorb hyoscyamine. If you use an antacid, take it after you have taken hyoscyamine and eaten a meal.\nDrinking alcohol with  hyoscyamine can cause side effects.\nAvoid becoming overheated or dehydrated during exercise and in hot weather. Hyoscyamine can decrease sweating and you may be more prone to heat stroke.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(373,'hytrin','Take Hytrin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.\nYour doctor may occasionally change your dose to make sure you get the best results.\nHytrin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it, or when you start taking it again. You may wish to take this medication only at bedtime if it causes you to feel light-headed. Call your doctor if you have severe dizziness or feel like you might pass out.\nYou may feel very dizzy when you first wake up. Be careful when standing or sitting up from a lying position.\nIf you stop taking Hytrin for any reason, call your doctor before you start taking it again. You may need a dose adjustment.\nYour blood pressure and/or prostate will need to be checked often. Visit your doctor regularly.\nIf you are being treated for high blood pressure, keep using Hytrin even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.\nSome things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.\nStore Hytrin at room temperature away from moisture, heat, and light.\n Detailed Hytrin dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nIf you miss your doses for several days in a row, contact your doctor before restarting the medication. You may need a lower dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include extreme dizziness or fainting.\n','Tell your doctor about all other medications you use, especially:\nsildenafil (Viagra, Revatio);\ntadalafil (Cialis);\nvardenafil (Levitra);\nverapamil (Calan, Covera, Isoptin, Verelan); or\nother blood pressure medications, including diuretics (water pills).\nThis list is not complete and other drugs may interact with Hytrin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\n Hytrin drug interactions (more detail)\n','Get emergency medical help if you have any of these signs of an allergic reaction to Hytrin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:\nfast or pounding heartbeats or fluttering in your chest;\nfeeling like you might pass out;\nswelling in your hands, ankles, or feet; or\npenis erection that is painful or lasts 4 hours or longer.\nLess serious Hytrin side effects may include:\nmild dizziness;\nweakness, drowsiness;\nblurred vision;\nnausea; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Hytrin side effects (more detail)\n','Hytrin (terazosin) is in a group of drugs called alpha-adrenergic blockers. Hytrin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.\nHytrin is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate).\nHytrin may also be used for other purposes not listed in this medication guide.\n','You should not use Hytrin if you are allergic to terazosin. Hytrin may cause dizziness or fainting, especially when you first start taking it or when you start taking it again. You may wish to take this medication only at bedtime if it causes you to feel light-headed. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.\nIf you stop taking Hytrin for any reason, call your doctor before you start taking it again. You may need a dose adjustment.\nHytrin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using Hytrin. Do not stop using Hytrin before surgery unless your surgeon tells you to.\nTell your doctor about all other medications you use, especially other blood pressure medications including diuretics (water pills).\nBefore taking this medicine\nHytrin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Hytrin before surgery unless your surgeon tells you to.\nIf you have a history of prostate cancer, you may need a dose adjustment or special tests to safely take Hytrin.\nYou should not use Hytrin if you are allergic to terazosin.\nFDA pregnancy category C. It is not known whether Hytrin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether terazosin passes into breast milk or if it could harm a nursing baby. Do not use Hytrin without telling your doctor if you are breast-feeding a baby.\n Hytrin pregnancy and breastfeeding warnings (more detail)\n','Hytrin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\nTo prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can increase certain side effects of Hytrin.\n'),(374,'hyzaar','Usual Adult Dose for Hypertension:\nHYPERTENSION:\nHydrochlorothiazide 12.5 to 25 mg-Losartan 50 to 100 mg orally once a day\nMaximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day\nComments:\n-A patient whose blood pressure is not adequately controlled with hydrochlorothiazide or losartan monotherapy may be switched to hydrochlorothiazide 12.5 mg-losartan 50 mg orally once a day.\n-May increase dose if blood pressure remains uncontrolled after about 3 weeks.\nUse: Treatment of hypertension. This drug is not indicated for initial therapy except when hypertension is severe enough that the benefit of achieving prompt blood pressure control exceeds the risk of initiating combination therapy.\nSEVERE HYPERTENSION:\nInitial treatment: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled after 2 to 4 weeks, may initiate maximum dose.\nMaximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day\nHYPERTENSION WITH LEFT VENTRICULAR HYPERTROPHY:\nInitial therapy: Losartan monotherapy; if blood pressure remains uncontrolled, may initiate this drug.\nAdd-on therapy: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled, initiate hydrochlorothiazide 12.5 mg-losartan 100 mg orally once a day, followed by hydrochlorothiazide 25 mg-losartan 100 mg orally once a day, if needed.\nUse: To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients.\n Detailed Hyzaar dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','If you also take cholestyramine or colestipol, take your Hyzaar dose 4 hours before or 4 to 6 hours after you take the other medicine.\nTell your doctor about all your other medicines, especially:\na diuretic or \"water pill\";\nother blood pressure medications;\nlithium; or\nNSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nThis list is not complete. Other drugs may interact with hydrochlorothiazide and losartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Hyzaar drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Hyzaar: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nirregular heartbeats;\neye pain, vision problems;\nkidney problems - little or no urination, rapid weight gain, swelling in your hands, feet, or ankles;\nnew or worsening symptoms of lupus - joint pain, and a skin rash on your cheeks or arms that worsens in sunlight; or\nsigns of an electrolyte imbalance - increased thirst or urination, confusion, vomiting, constipation, muscle pain, leg cramps, irregular heartbeats, numbness or tingling, severe weakness, loss of movement, feeling jittery or unsteady.\nCommon Hyzaar side effects may include:\ndizziness;\nback pain; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Hyzaar side effects (more detail)\n','Hyzaar contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.\nLosartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker). Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.\nHyzaar is used to treat high blood pressure (hypertension).\nHyzaar is also used to lower the risk of stroke in certain people with heart disease.\n','Do not use Hyzaar if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.\nYou should not use this medicine if you are unable to urinate.\nIf you have diabetes, do not use Hyzaar together with any medication that contains aliskiren (a blood pressure medicine).\nYou may also need to avoid taking Hyzaar with aliskiren if you have kidney disease.\nIn rare cases, Hyzaar can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.\nBefore taking this medicine\nYou should not use Hyzaar if you are allergic to hydrochlorothiazide or losartan, if you are unable to urinate.\nTo make sure Hyzaar is safe for you, tell your doctor if you have ever had:\nlupus;\nliver or kidney disease;\nasthma or allergies;\ndiabetes;\ngout;\ncongestive heart failure;\nglaucoma;\nlow or high levels of potassium in your blood;\nhigh cholesterol or triglyceride levels; or\nan allergy to penicillin or sulfa drugs.\nDo not use if Hyzaar you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Hydrochlorothiazide and losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.\nYou should not breast-feed while using this medicine.\nHow should I take Hyzaar?\nTake Hyzaar exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nYour blood pressure will need to be checked often.\nCall your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure.\nIf you need surgery or medical tests, tell the surgeon ahead of time that you are using Hyzaar.\nIf you have high blood pressure, keep using Hyzaar even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.\nStore at room temperature away from moisture, heat, and light.\n','Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis.\nDo not use potassium supplements or salt substitutes, unless your doctor has told you to.\nDrinking alcohol can further lower your blood pressure and may cause side effects.\nAvoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids.\n'),(375,'ibandronate','General\nCorrect hypocalcemia and other disturbances of bone and mineral metabolism prior to initiation of therapy.\nProvide supplemental calcium and vitamin D if dietary intake is inadequate.\nAdministration\nOral Administration\nAdminister orally with a full glass (180–240 mL) of plain water ≥60 minutes prior to the first food, beverage (other than plain water), or other orally administered drug or supplement (including vitamins, antacids, and calcium) of the day.   (See Food under Pharmacokinetics.)\nAvoid lying down for ≥60 minutes following administration.\nDo not to suck or chew tablets; potential for oropharyngeal ulceration. (See Upper GI Effects under Cautions.)\nIf a morning daily oral dose is missed, do not take missed dose later that same day. Resume the regular schedule the next day.\nWhen administered monthly, take tablets in the morning on the same day each month. If a monthly dose is missed and the next scheduled dose is more than 7 days away, take the missed dose the next morning after it is remembered and resume the regular schedule. If the next scheduled dose is 1–7 days away, maintain the regular schedule; do not take more than one 150-mg tablet within the same week.\nIV Administration\nAdminister by IV injection once every 3 months by a health-care professional. \nInjection must only be administered IV.  Safety and efficacy of IV injection administered by other routes not established.\nBecause of the risk of anaphylaxis or other severe hypersensitivity reactions, appropriate medical support should be readily available during IV administration. (See Hypersensitivity under Cautions.)\nIf a dose is missed, reschedule administration with a health-care professional as soon as possible. Schedule subsequent injections at 3-month intervals; should not be administered more often than once every 3 months.\nAdministration Risks\nTake care to avoid intra-arterial or paravenous injection as such administration could result in tissue damage.\nRate of Administration\nAdminister IV over a period of 15–30 seconds.\nDosage\nAvailable as ibandronate sodium (as the monosodium monohydrate); dosage expressed in terms of ibandronate. \nAdults\nOsteoporosis\nPrevention in Postmenopausal Women\n150 mg once monthly.\nOsteoporosis\nTreatment in Postmenopausal Women\n150 mg once monthly.\nOptimal duration of treatment not established. Safety and efficacy based on data over 3 years. Reevaluate need for continued therapy periodically in all patients receiving bisphosphonates. Consider discontinuance of bisphosphonate therapy after 3–5 years in patients at low risk of fracture. Evaluate fracture risk periodically in patients who discontinue therapy.\nIV\n3 mg once every 3 months.\nOptimal duration of treatment not established. Safety and efficacy of IV ibandronate based on data supporting fracture reduction over 1 year of treatment. Reevaluate need for continued therapy periodically in all patients receiving bisphosphonates. Consider discontinuance of bisphosphonate therapy after 3–5 years in patients at low risk of fracture. Evaluate fracture risk periodically in patients who discontinue therapy.\nSpecial Populations\nRenal Impairment\nOral or IV\nDosage adjustments not necessary in patients with mild to moderate renal impairment (Clcr ≥30 mL/minute); use not recommended in patients with severe renal impairment (Clcr <30 mL/minute).   \n Detailed Ibandronate dosage information\n','Does not induce or inhibit CYP isoenzymes (i.e., CYP1A2, 2A6, 2C9, 2C19, 2D6, 2E1, or 3A4)  and is not metabolized. \nAntacids or Mineral Supplements Containing Divalent Cations\nPharmacokinetic interaction (decreased absorption of ibandronate) when tablets are used concomitantly with antacids or mineral supplements containing divalent cations (e.g., aluminum, calcium, magnesium, iron). Administer tablets ≥60 minutes prior to such drugs or supplements.\nDrugs Affecting Hepatic Microsomal Enzymes\nPharmacokinetic interactions unlikely.\nDrugs Excreted through Renal Tubular Transport\nBased on limited data in animals, not excreted through renal tubular transport.   Pharmacokinetic interaction unlikely. \nNephrotoxic Agents\nPotential pharmacologic interaction (increased risk of renal toxicity).      Assess patients taking concomitant nephrotoxic agents. (See Renal Effects under Cautions.)\nSpecific Drugs and Tests\nDrug\nInteraction\nComments\nBone-imaging agents\nPotential to interfere with use of bone-imaging agents\nHistamine H2-receptor antagonists\nIncreased oral bioavailability of ibandronate \nNo evidence of increased adverse upper GI effects \nNot considered clinically important \nMelphalan\nPharmacokinetic interaction unlikely with IV ibandronate\nNSAIAs\nNo evidence of increased adverse upper GI effects\nUse concomitantly with caution\nPrednisolone\nPharmacokinetic interaction unlikely with IV ibandronate\nTamoxifen\nPharmacokinetic interaction unlikely with IV ibandronate\n Ibandronate drug interactions (more detail)\n',NULL,'Osteoporosis\nPrevention of osteoporosis in postmenopausal women. Risk factors for postmenopausal osteoporosis and related fractures include early menopause, advanced age, low bone mineral density (BMD), low body mass index (BMI), previous fracture or family history of fracture/osteoporosis, excessive alcohol intake, smoking, inadequate physical activity, low calcium and vitamin D intake, certain drugs (e.g., glucocorticoids), and medical conditions or diseases (e.g., rheumatoid arthritis, diabetes mellitus, Cushing syndrome, hyperparathyroidism). \nTreatment of osteoporosis in postmenopausal women.  \nIn addition to adequate intake of calcium/vitamin D and other lifestyle modifications (e.g., exercise, avoidance of excessive alcohol and tobacco use), experts recommend that pharmacologic therapy for osteoporosis be considered in postmenopausal women with previous hip or vertebral fractures or low BMD; pharmacologic therapy also may be considered in postmenopausal women with low bone mass, although there is less evidence supporting overall fracture risk reduction in such patients. \nUse of a drug with proven efficacy in reducing fracture risk is recommended; bisphosphonates (e.g., alendronate, risedronate, zoledronic acid, ibandronate) are recommended as one of several first-line drugs. \nIndividualize choice of therapy based on potential benefits (with respect to fracture risk reduction) and adverse effects of therapy, patient preferences, comorbidities, and risk factors. \nGlucocorticoid-induced Osteoporosis\nAlso has been used in the management of glucocorticoid-induced osteoporosis†. \nAmerican College of Rheumatology (ACR) recommends optimizing calcium and vitamin D intake and lifestyle modifications (e.g., diet, smoking cessation, weight-bearing or resistance-training exercise) in all patients receiving long-term glucocorticoid therapy; in addition, pharmacologic therapy with an oral bisphosphonate is recommended in patients who are considered to be at moderate-to-high risk of fracture. Oral bisphosphonates generally are preferred because of their demonstrated antifracture benefits, safety, and low cost.\n',NULL,NULL),(376,'ibrance','Usual Adult Dose for Breast Cancer:\n28-day cycle: 125 mg orally once a day for 21 consecutive days followed by 7 days off\nComments:\n-Administer the recommended dose of an aromatase inhibitor when given with this drug. Refer to the prescribing information for the aromatase inhibitor being used.\n-When given with this drug, the recommended dose of fulvestrant is 500 mg on Days 1, 15, 29, and once monthly thereafter. Refer to the prescribing Information for fulvestrant.\n-Pre/perimenopausal women treated with the combination of this drug plus fulvestrant should be treated with luteinizing hormone-releasing hormone (LHRH) agonists according to local protocol.\nUse: For HR-positive, HER2-negative advanced or metastatic breast cancer in combination with an aromatase inhibitor as initial endocrine-based therapy in postmenopausal women OR fulvestrant in women with disease progression following endocrine therapy.\n Detailed Ibrance dosage information\nWhat happens if I miss a dose?\nSkip the missed dose and do not take the medicine again until the next day. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with palbociclib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ibrance drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Ibrance: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nblisters or ulcers in your mouth, red or swollen gums, trouble swallowing;\nlow blood cell counts - fever, chills, weakness, dizziness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;\nsigns of inflammation in the lungs - new or worsening cough, painful or difficult breathing, wheezing, feeling short of breath even while resting; or\nsigns of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood.\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon Ibrance side effects may include:\nlow blood cell counts, infections;\neasy bruising or bleeding;\nfeeling weak or tired;\nnausea, vomiting, diarrhea, loss of appetite;\nmouth sores;\nabnormal liver function tests;\ndry skin, rash;\naltered sense of taste;\nnosebleed; or\nthinning hair or hair loss.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ibrance side effects (more detail)\n','Ibrance (palbociclib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.\nIbrance is used in men and women to treat HR-positive, HER2-negative breast cancer that has spread to other parts of the body.\nIn postmenopausal women, Ibrance is given in combination with a hormonal medicine such as letrozole (Femara). In others, Ibrance is given together with fulvestrant (Faslodex).\n','Ibrance affects your lungs or your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, chest pain, shortness of breath, or cough with or without mucus.\nBefore taking this medicine\nYou should not use Ibrance if you are allergic to palbociclib. Tell your doctor if you have signs of infection (such as fever or chills).\nTo make sure Ibrance is safe for you, tell your doctor if you have ever had:\nliver disease; or\nkidney disease.\nPalbociclib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.\nIf you are a woman, do not use palbociclib if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.\nIf you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.\nTell your doctor right away if a pregnancy occurs while either the mother or the father is using Ibrance.\nThis medicine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because palbociclib can harm an unborn baby.\nYou should not breastfeed while using palbociclib and for at least 3 weeks after your last dose.\nHow should I take Ibrance?\nTake Ibrance exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nIbrance is given in a 28-day treatment cycle, and you may only need to take the medicine during the first 3 weeks of each cycle. Your doctor will determine how long to treat you with Ibrance.\nTake Ibrance capsules with food. Avoid grapefruit products. Grapefruit may interact with palbociclib and lead to unwanted side effects.\nYou may take Ibrance tablets with or without food.\nTake the medicine at the same time each day.\nSwallow the capsule or tablet whole and do not crush, chew, break, or open it. Do not use a broken or damaged pill.\nIf you vomit after taking Ibrance, wait until the next day to take your next dose.\nPalbociclib affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.\nStore at room temperature away from moisture and heat.\n','Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\n'),(377,'ibrutinib','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Ibrutinib is usually taken until your body no longer responds to the medication.\nTake this medicine with a full glass of water, at the same time each day. Drink plenty of liquids while you are taking ibrutinib.\nSwallow the tablet or capsule whole and do not crush, chew, break, or open it.\nIf you need surgery or dental work, tell your surgeon or dentist you currently use this medicine. You may need to stop for a short time.\nCall your doctor if you have severe or ongoing diarrhea. You can easily become dehydrated while taking ibrutinib.\nIbrutinib affects your immune system. You may get infections more easily, even serious or fatal infections. You will need frequent medical tests.\nIbrutinib can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop. Bleeding may also happen inside your body, such as in your stomach or intestines, or in your brain.\nStore in the original package at room temperature, away from moisture and heat.\n Detailed Ibrutinib dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not take 2 doses on the same day.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may affect ibrutinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ibrutinib drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using ibrutinib and call your doctor at once if you have:\nsevere or ongoing diarrhea;\nchest pain, pounding heartbeats or fluttering in your chest, feeling like you might pass out;\nsevere headache, blurred vision, pounding in your neck or ears;\npale skin, cold hands and feet;\neasy bruising or bleeding (nosebleeds, bleeding gums);\nsigns of bleeding inside your body--dizziness, confusion, problems with speech, prolonged headache, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds;\nsigns of infection--fever, chills, weakness, mouth sores, cough with mucus, trouble breathing;\nkidney problems--little or no urinating, swelling in your feet or ankles; or\nsigns of tumor cell breakdown--tiredness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, tingling in your hands and feet or around your mouth;\nCommon side effects may include:\ndiarrhea, nausea;\nfever, cough, trouble breathing;\nblisters or ulcers in your mouth;\nfeeling tired;\nbruising, rash; or\nmuscle pain, bone pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ibrutinib side effects (more detail)\n','Ibrutinib is used to treat mantle cell lymphoma, marginal zone lymphoma, Waldenstrom\'s macroglobulinemia, chronic lymphocytic leukemia, and small lymphocytic lymphoma.\nIbrutinib is also used to treat chronic graft-versus-host disease.\nIbrutinib may also be used for purposes not listed in this medication guide.\n','Ibrutinib can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop.\nBleeding may also happen inside your body. Call your doctor at once if you have signs such as dizziness, confusion, headache, speech problems, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds.\nIbrutinib also affects your immune system. You may get infections more easily, even serious or fatal infections. Tell your doctor if you have a fever, chills, cough, mouth sores, or other signs of infection.\nBefore taking this medicine\nYou should not use ibrutinib if you are allergic to it.\nTell your doctor if you have ever had:\nan infection;\nliver disease;\nbleeding problems;\na heart rhythm disorder; or\nrisk factors for heart disease (such as diabetes, smoking, being overweight, having high blood pressure or high cholesterol).\nUsing ibrutinib may increase your risk of developing other types of cancer. Ask your doctor about your specific risk.\nBoth men and women using  ibrutinib should use birth control to prevent pregnancy. Ibrutinib can harm an unborn baby if the mother or father is using this medicine.\nKeep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ibrutinib .\nDo not breastfeed while using this medicine, and for at least 1 week after your last dose.\n','Grapefruit and Seville oranges may interact with ibrutinib and lead to unwanted side effects. Avoid the use of grapefruit products and orange marmalades.\n'),(378,'ibuprofen','Use ibuprofen exactly as directed on the label, or as prescribed by your doctor. Use the lowest dose that is effective in treating your condition.\nAn ibuprofen overdose can damage your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses).\nA child\'s dose is based on the age and weight of the child. Carefully follow the dosing instructions provided with children\'s ibuprofen for the age and weight of your child. Ask a doctor or pharmacist if you have questions.\nTake ibuprofen with food or milk to lessen stomach upset.\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nYou must chew the chewable tablet before you swallow it.\nStore at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.\n Detailed Ibuprofen dosage information\nWhat happens if I miss a dose?\nSince ibuprofen is used when needed, you may not be on a dosing schedule. Skip any missed dose if it\'s almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.\n','Ask your doctor before using ibuprofen if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.\nAsk a doctor or pharmacist before using ibuprofen with any other medications, especially:\ncyclosporine;\nlithium;\nmethotrexate;\na blood thinner (warfarin, Coumadin, Jantoven);\nheart or blood pressure medication, including a diuretic or \"water pill\"; or\nsteroid medicine (such as prednisone).\nThis list is not complete. Other drugs may interact with ibuprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Ibuprofen drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to ibuprofen (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nGet emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.\nStop using this medicine and call your doctor at once if you have:\nchanges in your vision;\nshortness of breath (even with mild exertion);\nswelling or rapid weight gain;\na skin rash, no matter how mild;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nliver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nlow red blood cells (anemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or\nkidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath.\nCommon ibuprofen side effects may include:\nnausea, vomiting, gas;\nbleeding; or\ndizziness, headache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ibuprofen side effects (more detail)\n','Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.\nIbuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury.\nIbuprofen is used in adults and children who are at least 6 months old.\n','Ibuprofen can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nIbuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.\nDo not take more than your recommended dose. An ibuprofen overdose can damage your stomach or intestines. Use only the smallest amount of medication needed to get relief from your pain, swelling, or fever.\nBefore taking this medicine\nYou should not use ibuprofen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.\nAsk a doctor or pharmacist if this medicine is safe to use if you have ever had:\nheart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;\na heart attack, stroke, or blood clot;\nstomach ulcers or bleeding;\nliver or kidney disease;\nasthma; or\nif you take aspirin to prevent heart attack or stroke.\nAsk a doctor before using this medicine if you are pregnant or breastfeeding.\nIf you are pregnant, you should not take ibuprofen unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.\nDo not give ibuprofen to a child younger than 6 months old without the advice of a doctor.\n','Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to ibuprofen (such as aspirin, ketoprofen, or naproxen).\nAvoid taking aspirin unless your doctor tells you to.\nIf you also take aspirin to prevent stroke or heart attack, taking ibuprofen can make aspirin less effective in protecting your heart and blood vessels. If you take both medicines, take ibuprofen at least 8 hours before or 30 minutes after you take aspirin (non-enteric coated form).\nAvoid drinking alcohol. It may increase your risk of stomach bleeding.\n'),(379,'iclusig','Usual Adult Dose for Chronic Myelogenous Leukemia:\nInitial Dose: 45 mg orally once a day\nComments: The optimal dose has not been identified. The starting dose in clinical trials was 45 mg once a day; however, 68% of phase 2 trial patients required dose reductions to 30 mg or 15 mg once a day.\nUses: Treatment of:\n-Chronic phase (CP), accelerated phase (AP), or blast phase (BP) chronic myeloid leukemia (CML) or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) for whom no other tyrosine kinase inhibitor (TKI) therapy is indicated.\n-T315I-positive CP/AP/BP CML or T315I-Ph+ ALL\n Detailed Iclusig dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can interact with ponatinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Iclusig drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Iclusig: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nIclusig may cause heart or blood vessel problems that could lead to heart attack or stroke. Call your doctor right away or get emergency medical help if you have:\nheart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, feeling short of breath;\nsigns of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; or\nsigns of a blood clot - severe stomach pain, pain or swelling in your arms or legs, coughing up blood.\nCall your doctor at once if you have:\ndizziness, confusion, headache, change in mental status;\na seizure;\nswelling, rapid weight gain, feeling short of breath;\na wound that will not heal;\neye problems - vision problems, eye pain or swelling, bleeding in the eye, increased sensitivity to light, flashes of light or \"floaters\" in your vision;\nheart problems - chest pain, shortness of breath, fast or pounding heartbeats, feeling like you might pass out;\na hole or tear in your stomach or intestine - severe pain or swelling in your stomach with a high fever;\nlow blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet;\nnerve problems - muscle weakness, trouble moving your eyes or other parts of your face, tingling, burning pain, numbness in your hands and feet;\nsevere bleeding - nosebleeds, bloody or tarry stools, pink or brown urine, heavy menstrual periods, coughing up blood or vomit that is bloody or looks like coffee grounds; or\nsigns of liver or pancreas problems - loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes).\nCommon Iclusig side effects include:\ndry skin, rash;\nstomach pain, nausea, vomiting, diarrhea, constipation;\nheadache, muscle or joint pain;\npain in your arms, hands, legs, or feet;\nincreased blood pressure; or\nfever, tired feeling.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Iclusig side effects (more detail)\n','Iclusig (ponatinib) is a cancer medicine that interferes with the growth of some cancer cells.\nIclusig is used in adults to treat a type of blood cancer called chronic myeloid leukemia (CML), or Philadelphia chromosome positive acute lymphoblastic leukemia (ALL).\nIclusig is usually given after other similar medications have been tried without success.\n','Iclusig may cause heart or blood vessel problems that could lead to heart attack, stroke, or death.\nCall your doctor or get emergency medical help if you have: chest pain spreading to your jaw or shoulder, shortness of breath, dizziness, severe stomach pain, swelling in your legs, sudden numbness or weakness, headache, or problems with vision or speech.\nIclusig may also harm your liver. Call your doctor right away if you have upper stomach pain with loss of appetite, dark urine, bruising, or yellowing of your skin or eyes.\nBefore taking this medicine\nYou should not use Iclusig if you are allergic to ponatinib.\nTo make sure Iclusig is safe for you, tell your doctor if you have ever had:\nheart failure, high blood pressure, heart rhythm problems;\nlong QT syndrome (in you or a family member);\na stroke or blood clot;\ndiabetes;\nhigh cholesterol;\nliver disease;\nbleeding problems;\nlactose intolerance (tablets may contain lactose);\npancreatitis; or\nif you\'ve had surgery within the past 2 weeks.\nYou may need to have a negative pregnancy test before starting this treatment.\nPonatinib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.\nThis medicine may affect fertility (ability to have children) in women. However, it is important to use birth control to prevent pregnancy because Iclusig can harm an unborn baby.\nYou should not breastfeed while using Iclusig and for at least 6 days after your last dose.\nHow should I take Iclusig?\nTake Iclusig exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nIclusig is usually taken once daily, with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nYou may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.\nIf you need surgery, tell the surgeon ahead of time that you are using Iclusig. You may need to stop using the medicine at least 1 week before a surgery.\nDo not stop taking Iclusig or change your medication dose without your doctor\'s advice.\nStore at room temperature away from moisture and heat.\n','Grapefruit may interact with ponatinib and lead to unwanted side effects. Avoid the use of grapefruit products.\n'),(380,'idhifa','Usual Adult Dose for Acute Myeloid Leukemia:\n100 mg orally once a day with or without food\nDuration of Therapy:\n-Treat until disease progression or unacceptable toxicity.\n-For patients without disease progression or unacceptable toxicity, treat for a minimum of 6 months to allow time for clinical response.\nComments: Select patients based on the presence of isocitrate dehydrogenase-2 (IDH2) mutations in the blood or bone marrow as detected by an FDA-approved test, http://www.fda.gov/CompanionDiagnostics.\nUse: Treatment of relapsed or refractory acute myeloid leukemia (AML) with an IDH2 mutation.\n Detailed Idhifa dosage information\nWhat happens if I miss a dose?\nTake the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not use 2 doses in one day.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with enasidenib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Idhifa drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Idhifa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nIdhifa can cause a condition called differentiation syndrome, which affects blood cells and can be fatal if not treated. This condition may occur within 10 days to 5 months after you start taking Idhifa.\nSeek medical help right away if you have symptoms of differentiation syndrome:\nfever, cough, trouble breathing;\nbone pain;\nrapid weight gain; or\nswelling in your arms, legs, underarms, groin, or neck.\nCall your doctor at once if you have any of these side effects:\ndark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nsevere or ongoing vomiting or diarrhea; or\nsigns of tumor cell breakdown - tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.\nCommon Idhifa side effects may include:\nnausea, vomiting, diarrhea;\nloss of appetite; or\njaundice.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Idhifa side effects (more detail)\n','Idhifa (enasidenib) targets a specific gene mutation called IDH2, which can affect your bone marrow. IDH2 mutation prevents young blood cells from developing into healthy adult blood cells, which can result in symptoms of acute myeloid leukemia.\nIdhifa is used to treat acute myeloid leukemia in adults with an IDH2 mutation.\nIdhifa is used when AML has come back or has not improved with prior treatment.\n','Idhifa can cause a condition called differentiation syndrome, which affects blood cells and can be fatal if not treated. This condition may occur within 10 days to 5 months after you start taking this medicine.\nSeek medical help right away if you have symptoms of differentiation syndrome: fever, cough, trouble breathing, bone pain, rapid weight gain, or swelling in your arms, legs, underarms, groin, or neck.\nBefore taking this medicine\nYou should not use Idhifa if you are allergic to enasidenib.\nBefore using Idhifa tell your doctor about all your medical conditions or allergies.\nYou may need to have a negative pregnancy test before starting this treatment. In animal studies, enasidenib caused miscarriage, low birth weight, stillbirth, and birth defects.\nEnasidenib may harm an unborn baby. Use a barrier form of birth control (condom or diaphragm with spermicide) to prevent pregnancy while you are using Idhifa. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment.\nYou should use birth control to prevent pregnancy while using this medicine whether you are a man or a woman. Idhifa use by either parent may cause birth defects.\nKeep using birth control for at least 2 months after your last dose of Idhifa. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using enasidenib.\nIdhifa may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because enasidenib may harm the baby if a pregnancy does occur.\nIt is not known whether enasidenib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine, and for at least 1 month after your last dose.\nHow should I take Idhifa?\nTake Idhifa exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nTake Idhifa exactly as prescribed by your doctor. Idhifa is usually given once per day. Take this medicine with a full glass of water, at the same time each day. Drink plenty of liquids while you are taking this medicine.\nYou may take this medicine with or without food.\nDo not crush, chew, or break a tablet. Swallow the tablet whole.\nIdhifa is usually given until your body no longer responds to the medication.\nIf you vomit shortly after taking Idhifa, do not take another dose. Take your next dose as scheduled.\nYou may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests.\nStore at room temperature away from moisture and heat. Keep the tablets in their original container, along with the canister of moisture-absorbing preservative.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(381,'ilumya','Usual Adult Dose of Ilumya for Plaque Psoriasis:\n100 mg subcutaneously at Weeks 0 and 4, and every 12 weeks thereafter\nComments:\n-Evaluate patients for tuberculosis (TB) infection prior to initiating therapy.\nUse: For adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy\nAdministration advice:\n-Ilumya should only be administered by a healthcare provider.\n-Before injection, remove carton from the refrigerator, and let the prefilled syringe (in the carton with the lid closed) sit at room temperature for 30 minutes.\n-Follow the instructions on the carton to remove the prefilled syringe correctly, and remove only when ready to inject. Do not pull off the needle cover until you are ready to inject.\n-Inspect the syringe visually for particulate matter and discoloration prior to administration. The product is a clear to slightly opalescent, colorless to slightly yellow solution. Do not use if the liquid contains visible particles or the syringe is damaged. Air bubbles may be present; there is no need to remove them.\n-Choose an injection site with clear skin and easy access (such as abdomen, thighs, or upper arm). Do not administer 2 inches around the navel or where the skin is tender, bruised, erythematous, indurated, or affected by psoriasis. Do not inject into scars, stretch marks, or blood vessels.\n-While holding the body of the syringe, pull the needle cover straight off (do not twist) and discard.\n-Inject the full amount (1 mL), which provides 100 mg of drug per syringe.\n-Press down the blue plunger until it can go no further. This activates the safety mechanism that will ensure full retraction of the needle after the injection is given.\n-Remove the needle from the skin entirely before letting go of the blue plunger. After the blue plunger is released, the safely lock will draw the needle inside the needle guard.\n-If a dose is missed, administer the dose as soon as possible; thereafter, resume dosing at the regularly scheduled interval.\n Detailed Ilumya dosage information\nWhat happens if I miss a dose?\nIf you miss a follow-up appointment and do not receive your dose, schedule another appointment as soon as possible.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with tildrakizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ilumya drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Ilumya: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nYou may get infections more easily, even serious or fatal infections. Call your doctor right away if you have signs of infection such as:\nfever, chills, sweating;\nskin sores;\nmuscle pain;\nincreased urination, pain or burning when you urinate;\nstomach pain, diarrhea, weight loss; or\ncough, shortness of breath, coughing up pink or red mucus.\nCommon Ilumya side effects may include:\npain, itching, rash, redness, swelling, bruising, or bleeding where the medicine was injected;\ndiarrhea; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ilumya side effects (more detail)\n','Ilumya (tildrakizumab) reduces the effects of a substance in the body that can cause inflammation.\nIlumya injection is a prescription medicine used to treat moderate to severe psoriasis in adults who may benefit from receiving injections, pills, or treatment using ultraviolet or UV light phototherapy).\nIlumya may also be used for purposes not listed in this medication guide.\n','Ilumya affects your immune system. You may get infections more easily. Call your doctor if you have a fever, chills, aches, cough, shortness of breath, skin sores, diarrhea, weight loss, or burning when you urinate.\nBefore receiving this medicine\nYou should not be treated with Ilumya if you are allergic to tildrakizumab\nTell your doctor if you have a chronic infection, or if you are scheduled to receive any vaccine.\nTell your doctor if you have ever had tuberculosis, or if anyone in your household has tuberculosis.\nIt is not known whether Ilumya will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breast-feed while using tildrakizumab. Ask your doctor about any risk.\nIlumya is not approved for use by anyone younger than 18 years old.\nHow is Ilumya given?\nIlumya is given as an injection under your skin (subcutaneous injection) in areas of your body such as your thighs, stomach area (abdomen), or upper arm.\nA healthcare provider will administer your Ilumya injection.\nBefore you start treatment with Ilumya, your doctor may perform tests to make sure you do not have tuberculosis or other infections.\n','Do not receive a \"live\" vaccine while using Ilumya. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).\n'),(382,'imatinib','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake imatinib with a meal and a large glass of water. Do not take imatinib on an empty stomach.\nIf you cannot swallow a tablet whole, you may dissolve it in a glass of water or apple juice to make the pill easier to swallow. Use about 2 ounces of liquid for each 100-milligram tablet, or 7 ounces of liquid for each 400-milligram tablet. Stir the mixture and drink all of it right away.\nDo not use a broken tablet. The medicine from a broken pill can be dangerous if it gets in your mouth, eyes, or nose, or on your skin. If this happens, wash your skin with soap and water or rinse your eyes with water. Ask your pharmacist how to safely dispose of a broken pill.\nImatinib can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.\nYou will also need frequent tests to check your liver function.\nDo not stop using imatinib without your doctor\'s advice.\nStore at room temperature away from moisture and heat.\n Detailed Imatinib dosage information\nWhat happens if I miss a dose?\nTake your dose as soon as you can, making sure you also eat a meal and drink a large glass of water. Skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nTell your doctor about all your current medicines. Many drugs can affect imatinib, especially:\nan antibiotic, antifungal, or antiviral medicine;\nseizure medicine;\na blood thinner such as warfarin (Coumadin, Jantoven); or\na vitamin or mineral supplement that contains iron.\nThis list is not complete and many other drugs may affect imatinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Imatinib drug interactions (more detail)\nDoes Imatinib interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nCall your doctor at once if you have:\nfluid retention--shortness of breath (even while lying down), swelling, rapid weight gain;\nkidney problems--little or no urination, swelling in your feet or ankles;\nfluid build-up in the lungs--pain when you breathe, wheezing, gasping for breath, cough with foamy mucus;\nliver problems--upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);\nlow blood cell counts--fever, cold or flu symptoms, easy bruising, unusual bleeding, mouth sores, pale skin, unusual tiredness, feeling light-headed, cold hands and feet;\nsigns of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nsigns of tumor cell breakdown--confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth; or\nthyroid symptoms--tiredness, dry skin, hair loss, constipation, depression, slow heart rate, weight gain, feeling more sensitive to cold temperatures.\nImatinib can affect growth in children and teenagers. Tell your doctor if your child is not growing at a normal rate while using this medicine.\nCommon side effects may include:\nfluid retention;\nnausea, vomiting, stomach pain, diarrhea;\njoint or muscle pain;\nskin rash; or\nfeeling tired.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imatinib side effects (more detail)\n','Imatinib is used to treat certain types of leukemia (blood cancer), bone marrow disorders, and skin cancer. Imatinib is also used to treat certain tumors of the stomach and digestive system.\nImatinib may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use imatinib if you are allergic to it.\nTell your doctor if you have ever had:\nliver disease (especially hepatitis B);\nkidney disease;\nunderactive thyroid, recent or upcoming thyroid surgery;\nheart disease, high blood pressure, congestive heart failure;\na stomach ulcer or bleeding;\ndiabetes; or\nchemotherapy.\nYou may need to have a negative pregnancy test before starting this treatment.\nDo not use imatinib if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using  imatinib and for at least 14 days after your last dose.\nDo not breast-feed a baby while you are using this medicine and for at least 1 month after your last dose.\n',' imatinib may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls, accidents, or severe injuries.\nGrapefruit may interact with imatinib and lead to unwanted side effects. Avoid the use of grapefruit products.\nAvoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\nAvoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.\n'),(383,'imbruvica','Usual Adult Dose for Lymphoma:\n560 mg orally once a day until disease progression or unacceptable toxicity\nUses:\n-For the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy\n-For the treatment of adult patients with marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy\nUsual Adult Dose for Chronic Lymphocytic Leukemia:\nAs a single agent or in combination with bendamustine and rituximab or with obinutuzumab:\n420 mg orally once daily until disease progression or unacceptable toxicity\nComments:\n-Consider administering this drug prior to rituximab or obinutuzumab when given on the same day.\nUses:\n-For the treatment of adult patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)\n-For the treatment of adult patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) with 17p deletion\nUsual Adult Dose for non-Hodgkin\'s Lymphoma:\n420 mg orally once a day\nDuration of Therapy:\n-WM: Until disease progression or unacceptable toxicity\n-cGVHD: Until disease progression, recurrence of an underlying malignancy, or unacceptable toxicity\nComments:\n-WM: Management of hyperviscosity may include plasmapheresis before and during therapy, which will not require dosing modifications.\n-cGVHD: When a patient no longer requires therapy, discontinue this drug considering the medical assessment of the individual patient.\nUses:\n-For the treatment of adult patients with Waldenstrom\'s macroglobulinemia (WM)\n-For the treatment of adult patients with chronic graft-versus-host disease (cGVHD) after failure of one or more lines of systemic therapy\nUsual Adult Dose for Graft Versus Host Disease:\n420 mg orally once a day\nDuration of Therapy:\n-WM: Until disease progression or unacceptable toxicity\n-cGVHD: Until disease progression, recurrence of an underlying malignancy, or unacceptable toxicity\nComments:\n-WM: Management of hyperviscosity may include plasmapheresis before and during therapy, which will not require dosing modifications.\n-cGVHD: When a patient no longer requires therapy, discontinue this drug considering the medical assessment of the individual patient.\nUses:\n-For the treatment of adult patients with Waldenstrom\'s macroglobulinemia (WM)\n-For the treatment of adult patients with chronic graft-versus-host disease (cGVHD) after failure of one or more lines of systemic therapy\n Detailed Imbruvica dosage information\nWhat happens if I miss a dose?\nTake the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not take 2 doses on the same day.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with ibrutinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Imbruvica drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction t0 Imbruvica: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using Imbruvica and call your doctor at once if you have:\nsevere or ongoing diarrhea;\nchest pain, pounding heartbeats or fluttering in your chest, feeling like you might pass out;\nsevere headache, blurred vision, pounding in your neck or ears;\npale skin, cold hands and feet;\neasy bruising or bleeding (nosebleeds, bleeding gums);\nsigns of bleeding inside your body - dizziness, confusion, problems with speech, prolonged headache, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds;\nsigns of infection - fever, chills, weakness, mouth sores, cough with mucus, trouble breathing;\nkidney problems - little or no urinating, swelling in your feet or ankles; or\nsigns of tumor cell breakdown - tiredness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, tingling in your hands and feet or around your mouth;\nCommon Imbruvica side effects may include:\ndiarrhea, nausea;\nfever, cough, trouble breathing;\nblisters or ulcers in your mouth;\nfeeling tired;\nbruising, rash; or\nmuscle pain, bone pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imbruvica side effects (more detail)\n','Imbruvica (ibrutinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.\nImbruvica is used to treat mantle cell lymphoma, marginal zone lymphoma, Waldenstrom\'s macroglobulinemia, chronic lymphocytic leukemia, and small lymphocytic lymphoma.\nImbruvica is also used to treat chronic graft-versus-host disease.\n','Imbruvica can make it easier for you to bleed. Contact your doctor or seek emergency medical attention if you have easy bruising, unusual bleeding, or any bleeding that will not stop.\nCall your doctor at once if you have signs of bleeding inside your body, such as: dizziness, confusion, headache, speech problems, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds.\nImbruvica also affects your immune system. You may get infections more easily, even serious or fatal infections. Tell your doctor if you have a fever, chills, cough, mouth sores, or other signs of infection.\nBefore taking this medicine\nYou should not use Imbruvica if you are allergic to ibrutinib.\nTo make sure Imbruvica is safe for you, tell your doctor if you have:\nan infection;\nliver disease;\nbleeding problems;\na heart rhythm disorder; or\nrisk factors for heart disease (such as diabetes, smoking, being overweight, having high blood pressure or high cholesterol).\nUsing Imbruvica may increase your risk of developing other types of cancer. Ask your doctor about your specific risk.\nBoth men and women using Imbruvica should use birth control to prevent pregnancy. Ibrutinib can harm an unborn baby if the mother or father is using this medicine.\nKeep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Imbruvica .\nDo not breastfeed while using this medicine, and for at least 1 week after your last dose.\nHow should I take Imbruvica?\nTake Imbruvica exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Imbruvica is usually taken until your body no longer responds to the medication.\nTake this medicine with a full glass of water, at the same time each day. Drink plenty of liquids while you are taking Imbruvica.\nSwallow the tablet or capsule whole and do not crush, chew, break, or open it.\nIf you need surgery or dental work, tell your surgeon or dentist you currently use this medicine. You may need to stop for a short time.\nCall your doctor if you have severe or ongoing diarrhea. You can easily become dehydrated while taking Imbruvica.\nIbrutinib affects your immune system. You may get infections more easily, even serious or fatal infections. You will need frequent medical tests.\nImbruvica can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop. Bleeding may also happen inside your body, such as in your stomach or intestines, or in your brain.\nStore in the original package at room temperature, away from moisture and heat.\n','Grapefruit and Seville oranges may interact with ibrutinib and lead to unwanted side effects. Avoid the use of grapefruit products and orange marmalades.\n'),(384,'imdur','Usual Adult Dose for Angina Pectoris Prophylaxis:\nEXTENDED RELEASE:\n30 to 60 mg orally once a day in the morning\nMaximum dose: 240 mg orally once a day in the morning\nComments:\n-Swallow whole (do not crush or chew) with half-glass of fluid.\n-Start at low end of dosing range for elderly patients.\nUse: Prevention of angina pectoris due to coronary artery disease; onset of action is not sufficiently rapid to be useful in aborting an acute anginal episode.\nUsual Adult Dose for Angina Pectoris:\nEXTENDED RELEASE:\n30 to 60 mg orally once a day in the morning\nMaximum dose: 240 mg orally once a day in the morning\nComments:\n-Swallow whole (do not crush or chew) with half-glass of fluid.\n-Start at low end of dosing range for elderly patients.\nUse: Prevention of angina pectoris due to coronary artery disease; onset of action is not sufficiently rapid to be useful in aborting an acute anginal episode.\n Detailed Imdur dosage information\n','Taking Imdur with certain other medicines can cause severely low blood pressure. This includes medicine to treat erectile dysfunction or pulmonary arterial hypertension. Serious, life-threatening side effects may occur.\nTell your doctor about all your current medicines and any you start or stop using, especially:\navanafil (Stendra);\na diuretic or \"water pill\";\nnitroglycerin;\nriociguat (Adempas);\nsildenafil (Viagra, Revatio);\ntadalafil (Cialis, Adcirca); or\nvardenafil (Levitra, Staxyn).\nThis list is not complete. Other drugs may interact with isosorbide mononitrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Imdur drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Imdur: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nworsening angina pain;\nfast or slow heart rate; or\npounding heartbeats or fluttering in your chest.\nImdur can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin. Do not stop taking this medicine to avoid headaches. Ask your doctor before using any headache pain medication.\nCommon Imdur side effects may include:\nheadache; or\nflushing (warmth, redness, or tingly feeling).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imdur side effects (more detail)\n','Imdur (isosorbide mononitrate) is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.\nImdur is an extended release tablet used to prevent angina attacks (chest pain).\nImdur will not treat an angina attack that has already begun.\n','You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking Imdur. Taking these medicine together can cause a sudden and serious decrease in blood pressure.\nSeek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, sweating, general ill feeling).\nDo not stop taking this medicine suddenly. Stopping suddenly could cause a severe angina attack.\nIsosorbide mononitrate can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use the medication. Do not stop taking Imdur. Ask your doctor before using any headache pain medication.\nUse this medicine regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely.\nBefore taking this medicine\nYou should not use Imdur if:\nyou are allergic to isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin; or\nyou have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating).\nYou should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking Imdur. Taking these medicines together can cause a sudden and serious decrease in blood pressure.\nTo make sure Imdur is safe for you, tell your doctor if you have:\ncongestive heart failure;\nkidney disease; or\nlow blood pressure.\nIt is not known whether Imdur will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether isosorbide mononitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.\nHow should I take Imdur?\nTake Imdur exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. If you use too much isosorbide mononitrate, it might stop working as well in controlling your condition.\nTry to rest or stay seated when you take this medicine (may cause dizziness or fainting).\nDo not crush, chew, or break an extended-release Imdur tablet. Swallow it whole.\nYou may have very low blood pressure while taking Imdur. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Prolonged illness can lead to a serious electrolyte imbalance, making it dangerous for you to use this medicine.\nUse Imdur regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely.\nYou should not stop using Imdur suddenly or you could have a severe attack of angina. Keep this medicine on hand at all times. Get your prescription refilled before you run out of medicine completely.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of isosorbide mononitrate can be fatal.\nOverdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions).\n','This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\nAvoid drinking alcohol. Alcohol may increase certain side effects of Imdur (dizziness, drowsiness, feeling light-headed, or fainting).\n'),(385,'imfinzi','Usual Adult Dose for Non-Small Cell Lung Cancer:\n10 mg/kg IV over 60 minutes every 2 weeks until disease progression, unacceptable toxicity, or a maximum of 12 months\nUse: For patients with unresectable Stage III non-small cell lung cancer (NSCLC) whose disease has not progressed following concurrent platinum-based chemotherapy and radiation therapy\nUsual Adult Dose for Small Cell Lung Cancer:\n30 kg or less:\n20 mg/kg IV every 3 weeks (21 days) for 4 cycles, followed by 20 mg/kg every 4 weeks as a single agent until weight increases to greater than 30 kg\nNOTE: When this drug is given in combination with chemotherapy, administer this drug prior to chemotherapy on the same day; refer to the Prescribing Information for etoposide and carboplatin or cisplatin for dosing information.\nGreater than 30 kg:\n1500 mg IV every 3 weeks (21 days) for 4 cycles, followed by 1500 mg every 4 weeks as a single agent until disease progression or unacceptable toxicity\nNOTE: When this drug is given in combination with chemotherapy, administer this drug prior to chemotherapy on the same day; refer to the Prescribing Information for etoposide and carboplatin or cisplatin for dosing information.\nUse: This drug in combination with etoposide and either carboplatin or cisplatin, for the first-line treatment of adult patients with extensive-stage small cell lung cancer (ES-SCLC)\n Detailed Imfinzi dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Imfinzi injection.\nWhat happens if I overdose?\nSince this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.\n','Other drugs may interact with durvalumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Imfinzi drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Imfinzi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome side effects may occur during the injection. Tell your caregiver right away if you feel light-headed or itchy, or if you have a fever, chills, neck or back pain, trouble breathing, or flushing (warmth, redness, or tingly feeling).\nDurvalumab causes your immune system to attack tumor cells, but it could also attack healthy organs and tissues in your body. This could lead to serious or life-threatening side effects on your lungs, liver, pancreas, kidneys, intestines, thyroid, or adrenal glands.\nCall your doctor at once if you have:\nchest pain, new or worsening cough, feeling short of breath;\nsevere stomach pain, diarrhea, bloody or tarry stools;\nnew or worsening skin rash, itching, or blistering;\nfever, flu-like symptoms;\npain or burning when you urinate;\nproblems in other organs - mood or behavior changes, neck stiffness, confusion, eye pain or redness, vision problems;\nliver problems - loss of appetite, upper stomach pain, drowsiness, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes);\nkidney problems - little or no urination, red or pink urine, swelling in your feet or ankles;\ntransplant rejection - rash with blisters and peeling, watery diarrhea, stomach pain, vomiting, loss of appetite, fever, bruising or bleeding, jaundice, pain or swelling near your transplanted organ; or\nsigns of a hormonal disorder - unusual headaches, feeling light-headed or very tired, hoarse or deepened voice, increased hunger or thirst, increased urination, constipation, vomiting, hair loss, feeling cold, weight gain, or weight loss.\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nCommon Imfinzi side effects may include:\nnausea, constipation;\ndecreased appetite;\nfeeling weak or tired;\nbone or muscle pain;\ncough, feeling short of breath;\ncold symptoms such as stuffy nose, sneezing, sore throat;\npainful urination;\nhair loss;\nrash; or\nswelling in your arms and legs.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imfinzi side effects (more detail)\n','Imfinzi (durvalumab) is a cancer medicine that works with your immune system to interfere with the growth and spread of cancer cells in the body.\nImfinzi is used to treat non-small cell lung cancer in patients whose tumors cannot be removed by surgery, and whose cancer has not progressed after treatment with chemotherapy and radiation (chemoradiation).\nImfinzi is also used to treat small cell lung cancer in combination with the chemotherapy medicines etoposide and carboplatin or cisplatin when the cancer has spread within your lungs or to other parts of the body.\n','Imfinzi works by causing your immune system to attack tumor cells. Durvalumab may cause your immune system to attack healthy organs and tissues in your body. This could lead to serious or life-threatening side effects on your lungs, liver, pancreas, kidneys, intestines, thyroid, pituitary, or adrenal glands.\nCall your doctor at once if you have new or unusual symptoms, such as: tiredness, mood changes, headaches, vision problems, muscle weakness, stomach problems, weight changes, skin rash, hair loss, bleeding or bruising, yellowing of your skin or eyes, increased or decreased urination, dark urine, bloody or tarry stools, worsening cough, chest pain, or trouble breathing.\nBefore taking this medicine\nYou should not use Imfinzi if you are allergic to durvalumab.\nTo make sure Imfinzi is safe for you, tell your doctor if you have have an active infection, or if you have ever had:\nan organ transplant or a stem cell transplant (recent or planned);\nlung disease or breathing problems;\nliver disease;\nradiation treatment of your chest area; or\nan autoimmune disorder such as lupus, ulcerative colitis, or Crohn\'s disease.\nImfinzi may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.\nDo not breastfeed while using Imfinzi, and for at least 3 months after your last dose.\nHow is Imfinzi given?\nImfinzi is given as an infusion into a vein, usually once every 2, 3 or 4 weeks. A healthcare provider will give you this injection.\nThis medicine must be given slowly and the infusion can take about 1 hour to complete.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(386,'imipramine','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nTell your doctor if you have a planned surgery.\nCall your doctor if your symptoms do not improve, or if they get worse.\nYou should not stop using imipramine suddenly. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Imipramine dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of imipramine can be fatal.\nOverdose symptoms may include irregular heartbeats, feeling like you might pass out, seizures, or coma.\n','Taking  imipramine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking imipramine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.\nMany drugs can affect imipramine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all other medicines you use.\n Imipramine drug interactions (more detail)\nDoes Imipramine interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\neasy bruising, unusual bleeding, purple or red spots under your skin;\ntunnel vision, eye pain or swelling, or seeing halos around lights;\na light-headed feeling, like you might pass out;\nnew or worsening chest pain, pounding heartbeats or fluttering in your chest;\nsudden numbness or weakness, problems with vision, speech, or balance;\nfever, sore throat;\nconfusion, hallucinations, unusual thoughts or behavior;\npainful or difficult urination;\nseizure (convulsions); or\njaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nincreased blood pressure;\ntingly feeling, weakness, lack of coordination;\ndry mouth, nausea, vomiting; or\nbreast swelling (in men or women).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imipramine side effects (more detail)\n','Imipramine is a tricyclic antidepressant used to treat symptoms of depression. Imipramine is sometimes used to treat bed-wetting in children ages 6 and older.\nImipramine may also be used for purposes not listed in this medication guide.\n','Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nBefore taking this medicine\nYou should not use imipramine if you are allergic to it, or if:\nyou recently had a heart attack; or\nyou are allergic to other antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, nortriptyline, protriptyline, or trimipramine).\nDo not use imipramine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.\nTell your doctor if you have used an \"SSRI\" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.\nTell your doctor if you have ever had:\nheart disease, stroke, or seizures;\nbipolar disorder (manic-depression), schizophrenia or other mental illness;\nkidney or liver disease;\noveractive thyroid;\nnarrow-angle glaucoma; or\nproblems with urination.\nSome young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nIt is not known whether  imipramine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nYou should not breastfeed while using imipramine.\nDo not give this medicine to a child without medical advice. Imipramine is not approved to treat depression in anyone younger than 18 years old. Imipramine should not be used to treat bed-wetting in a child younger than 6 years old.\n','Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with imipramine.\nAvoid driving or hazardous activity until you know how  imipramine will affect you. Your reactions could be impaired.\nAvoid exposure to sunlight or tanning beds. Imipramine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.\n'),(387,'imitrex','Usual Adult Dose for Migraine:\nUse only after a clear diagnosis of migraine has been established\nOral:\nInitial dose: 25 mg, 50 mg, or 100 mg orally, once\n-If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose if needed\n-Oral doses of 50 and 100 mg may provide greater relief than 25 mg; however, a 100 mg dose may not provide greater effect than a 50 mg dose\nMaximum dose: 200 mg per 24 hours\nIntranasal:\nNasal spray: Initial dose: 5 mg, 10 mg, or 20 mg into one nostril, once\n-Administer the 5 and 20 mg doses as a single spray in 1 nostril; the 10 mg dose may be administered as 5 mg into each nostril\n-If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose if needed\nMaximum dose: 40 mg per 24 hours\nComments:\n-Treatment should be started at the first sign of a migraine headache, or associated symptoms such as nausea, vomiting, or photophobia; this drug should not be used for migraine prophylaxis.\n-Higher doses may have a greater effect, but also carry a greater risk of adverse reactions.\n-The safety of treating an average of more than 4 headaches in a 30 day period has not been established.\nUse: For the acute treatment of migraine with or without aura.\n Detailed Imitrex dosage information\nWhat happens if I miss a dose?\nSince Imitrex is used when needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using this medicine.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include tremors, skin redness in your arms or legs, weakness, loss of coordination, breathing problems, blue-colored lips or fingernails, vision problems, or a seizure (convulsions).\n','Using Imitrex while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called \"serotonin syndrome,\" which can be fatal. Tell your doctor if you also use:\nmedicine to treat depression or a psychiatric disorder;\nmedicine for Parkinson\'s disease;\nmedicine for serious infections;\nherbal products;\nstimulant medicine;\nopioid medicine; or\nmedicine to prevent nausea and vomiting.\nThis list is not complete. Other drugs may interact with sumatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Imitrex drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Imitrex: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nStop using Imitrex and call your doctor at once if you have:\nsudden and severe stomach pain and bloody diarrhea;\nsevere chest pain, shortness of breath, irregular heartbeats;\na seizure (convulsions);\nsevere headache, blurred vision, pounding in your neck or ears;\nblood circulation problems in your legs or feet - cramps, tight or heavy feeling, numbness or tingling, muscle weakness, burning pain, cold feeling, color changes (pale or blue), hip pain;\nheart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;\nhigh levels of serotonin in the body - agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, vomiting, diarrhea; or\nsigns of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.\nCommon Imitrex side effects may include:\npain or tight feeling in your chest, throat, or jaw;\npressure or heavy feeling in any part of your body;\nnumbness or tingling, feeling hot or cold;\ndizziness, drowsiness, weakness;\nunusual or unpleasant taste in your mouth after using the nasal medicine;\npain, burning, numbness, or tingling in your nose or throat after using the nasal medicine; or\nrunny or stuffy nose after using the nasal medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imitrex side effects (more detail)\n','Imitrex (sumatriptan) is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.\nImitrex is available as oral tablets, a nasal spray, and as an injection. It used to treat migraine headaches in adults. Imitrex will only treat a headache. It will not prevent headaches or reduce the number of attacks.\nImitrex should not be used to treat a common tension headache or a headache that causes loss of movement on one side of your body. Use this medicine only if your condition has been confirmed by a doctor as migraine headaches.\n','You should not use Imitrex if you have uncontrolled high blood pressure, heart problems, certain heart rhythm disorders, a history of heart attack or stroke, or circulation problems that cause a lack of blood supply within the body.\nDo not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.\nAlso tell your doctor if you are taking an antidepressant such as citalopram (Celexa), desvenlafaxine (Pristiq), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor).\nImitrex will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.\nDo not use Imitrex within 24 hours before or after using any other migraine headache medicine.\nBefore taking this medicine\nYou should not use Imitrex if you are allergic to sumatriptan, or if you have ever had:\nheart problems, or a stroke (including \"mini-stroke\");\ncoronary artery disease, angina (chest pain), blood circulation problems, lack of blood supply to the heart;\ncirculation problems affecting your legs, arms, stomach, intestines, or kidneys;\na heart disorder called Wolff-Parkinson-White syndrome;\nuncontrolled high blood pressure;\nsevere liver disease; or\na headache that seems different from your usual migraine headaches.\nDo not use Imitrex if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nBe sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, serious infections, or prevention of nausea and vomiting. These medicines may interact with sumatriptan and cause a serious condition called serotonin syndrome.\nTo make sure Imitrex is safe for you, tell your doctor if you have ever had:\nliver or kidney disease;\nepilepsy or other seizure disorder;\nhigh blood pressure, a heart rhythm disorder; or\nrisk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, or being older than 40 and a man).\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nSumatriptan can pass into breast milk. Do not breast-feed within 12 hours after using Imitrex. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.\nImitrex is not approved for use by anyone younger than 18 years old.\nHow should I use Imitrex?\nUse Imitrex as soon as you notice headache symptoms. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nYou may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nTake a Imitrex tablet whole with a full glass of water. Do not split the tablet.\nAfter using Imitrex: If your headache does not completely go away, or goes away and comes back, use a second dose if it has been at least 2 hours since your first dose.\nNever use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.\nDo not take more than 200 milligrams of oral Imitrex within 24 hours.\nDo not use more than 40 milligrams of Imitrex nasal spray within 24 hours.\nCall your doctor if your symptoms do not improve, or if you have more than 4 headaches in one month (30 days).\nStore at room temperature away from moisture, heat, and light. Do not store in a refrigerator. Do not freeze.\n','Do not use Imitrex within 24 hours before or after using another migraine headache medicine, including:\nsumatriptan injection, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, zolmitriptan; or\nergot medicine such as dihydroergotamine, ergotamine, ergonovine, or methylergonovine.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(388,'imodium','This section provides information on the proper use of a number of products that contain loperamide.  It may not be specific to Imodium. Please read with care.\nTake this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.\nSwallow the capsule whole. Do not crush, break, or chew it.\nDrink plenty of water while using this medicine.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor acute diarrhea:\nFor oral dosage form (capsules):\nAdults and children 13 years of age and older—At first, 4 milligrams (mg) (2 capsules) after the first loose bowel movement, then 2 mg (1 capsule) after each loose bowel movement after the first dose has been taken. However, dose is usually not more than 16 mg (8 capsules).\nChildren 8 to 12 years of age weighing more than 30 kilograms (kg)—2 mg (1 capsule) 3 times a day.\nChildren 6 to 8 years of age weighing 20 to 30 kg—2 mg (1 capsule) 2 times a day.\nChildren 2 to 5 years of age weighing 20 kg or less—Use the oral solution.\nChildren younger than 2 years of age—Use is not recommended.\nFor oral dosage form (oral solution):\nChildren 8 to 12 years of age weighing more than 30 kilograms (kg)—2 teaspoonfuls (2 mg) 3 times a day.\nChildren 6 to 8 years of age weighing 20 to 30 kg—2 teaspoonfuls (2 mg) 3 times a day.\nChildren 2 to 5 years of age weighing 13 to 20 kg—1 teaspoonful (1 mg) 3 times a day.\nChildren younger than 2 years of age—Use is not recommended.\nFor oral dosage form (tablets):\nAdults and teenagers—The usual dose is 4 mg (2 tablets) after the first loose bowel movement, and 2 mg (1 tablet) after each loose bowel movement after the first dose has been taken. No more than 8 mg (4 tablets) should be taken in any 24-hour period.\nChildren 9 to 11 years of age—The usual dose is 2 mg (1 tablet) after the first loose bowel movement, and 1 mg (½ tablet) after each loose bowel movement after the first dose has been taken. No more than 6 mg (3 tablets) should be taken in any 24-hour period.\nChildren 6 to 8 years of age—The usual dose is 2 mg (1 tablet) after the first loose bowel movement, and 1 mg (½ tablet) after each loose bowel movement after the first dose has been taken. No more than 4 mg (2 tablets) should be taken in any 24-hour period.\nChildren up to 6 years of age—Use is not recommended unless directed by your doctor.\nFor chronic diarrhea:\nFor oral dosage form (capsules):\nAdults—At first, 4 milligrams (mg) (2 capsules) after the first loose bowel movement, then 2 mg (1 capsule) after each loose bowel movement after the first dose has been taken. Your doctor may adjust your dose as needed. However, dose is usually not more than 16 mg (8 capsules) per day.\nChildren 2 years of age and older—Use and dose must be determined by your doctor.\nChildren younger than 2 years of age—Use is not recommended.\nMissed dose\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Imodium dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nRare\nBloating\nconstipation\nloss of appetite\nnausea\nstomach pain\nvomiting\nIncidence not known\nBlistering, peeling, loosening of skin\nchest pain or discomfort\nchills\ncough\ndecrease in urine volume\ndecrease in frequency of urination\ndifficulty in passing urine\ndiarrhea\nfainting\nfast, pounding, or irregular heartbeat or pulse\nhives or welts, itching, rash\nirregular or slow heartbeat\njoint or muscle pain\nlarge, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs\nno blood pressure or pulse\npainful urination\npalpitations\nred irritated eyes\nredness of the skin\nred skin lesions, often with a purple center\nsores, ulcers, or white spots in the mouth or on the lips\nsore throat\nstopping of heart\nunconsciousness\nunusual tiredness or weakness\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nRare\nAcid or sour stomach\nbelching\ndizziness\ndrowsiness\ndryness of mouth\nexcess air or gas in the stomach or bowels\nfull feeling\nheartburn\nindigestion\npassing gas\nstomach upset\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Imodium side effects (more detail)\n','Loperamide is used to control and relieve the symptoms of acute diarrhea. It is also used to treat chronic diarrhea in patients with inflammatory bowel disease. Loperamide helps stop diarrhea by slowing down the movements of the intestines.\nLoperamide is also used to decrease the amount of drainage in patients who have ileostomies.\nLoperamide capsules are available only with your doctor\'s prescription.\n','If you will be taking this medicine for chronic diarrhea, it is very important that your doctor check you at regular visits for any problems or unwanted effects that may be caused by this medicine. If you will be taking this medicine for acute diarrhea, you should not use it for more than 2 days, unless directed by your doctor.\nCheck with your doctor if your diarrhea does not stop after two days or if you develop a fever.\nThis medicine may cause heart rhythm problems (eg, torsades de pointes, ventricular arrhythmias). Check with your doctor right away if you or your child have chest pain or discomfort, fast, slow, or irregular heartbeat, fainting, or trouble breathing.\nLoperamide may increase your risk for stomach or bowel problems. Check with your doctor right away if you have bloating, blood in the stools, constipation, fever, loss of appetite, nausea or vomiting, or stomach pain.\nThis medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Check with your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.\nThis medicine may cause some people to become dizzy, or drowsy, or tired. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.\n',NULL),(389,'imodium','Use Imodium A-D exactly as directed on the label, or as prescribed by your doctor.\nImodium A-D is safe when used as directed. TAKING TOO MUCH LOPERAMIDE CAN CAUSE SERIOUS HEART PROBLEMS OR DEATH.\nCarefully follow all dosing directions on the medicine label. A safe dose of loperamide is different for an adult than for a child. This medicine doses in children are based on the child\'s age.\nTake Imodium A-D with a full glass of water. Diarrhea can cause your body to lose fluids and electrolytes. Drink plenty of liquids to keep from getting dehydrated.\nThe chewable tablet must be chewed before swallowing. Take the chewable tablet on an empty stomach (1 hour before or 2 hours after a meal)\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nNot all liquid forms of this medicine are the same strengths. Carefully follow all dosing instructions for the medicine you are using.\nStore at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.\nStop taking Imodium A-D and call your doctor if you still have diarrhea after 2 days of treatment, or if you also have stomach bloating.\n Detailed Imodium A-D dosage information\nWhat happens if I miss a dose?\nSince Imodium A-D is used when needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using this medicine.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of loperamide can be fatal.\nOverdose symptoms may include fast or irregular heartbeats, or fainting. A person caring for you should seek emergency medical attention if you pass out and are hard to wake up.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take. Ask a doctor or pharmacist about safely using medications together.\nLoperamide can cause a serious heart problem with high doses.\nMany drugs can affect loperamide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Imodium A-D drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Imodium A-D (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop taking this medicine and call your doctor at once if you have:\ndiarrhea that is watery or bloody;\nstomach pain or bloating;\nongoing or worsening diarrhea; or\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out).\nCommon Imodium A-D side effects may include:\nconstipation;\ndizziness, drowsiness;\nnausea; or\nstomach cramps.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imodium A-D side effects (more detail)\n','Imodium A-D (loperamide) slows the rhythm of digestion so that the small intestines have more time to absorb fluid and nutrients from the foods you eat.\nImodium A-D is used to treat diarrhea.\nImodium A-D is also used to reduce the amount of stool in people who have an ileostomy (re-routing of the bowel through a surgical opening in the stomach).\n','You should not use Imodium A-D if you have ulcerative colitis, bloody or tarry stools, diarrhea with a high fever, or diarrhea caused by antibiotic medication.\nDo not take more than the recommended dose of this medicine. Misuse of loperamide can cause serious heart problems that could be fatal.\nSerious heart problems may also happen if you take Imodium A-D with other medicines. Ask a doctor or pharmacist about safely using medications together.\nLoperamide may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\nImodium A-D should not be given to a child younger than 2 years old. Loperamide can cause serious breathing problems and heart problems in a child.\nDrink plenty of liquids while you are taking this medicine. It may take up to 48 hours of taking Imodium A-D before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 10 days of treatment.\nBefore taking this medicine\nYou should not use Imodium A-D if you are allergic to loperamide, or if you have:\nstomach pain without diarrhea;\ndiarrhea with a high fever;\nulcerative colitis;\ndiarrhea that is caused by a bacterial infection; or\nstools that are bloody, black, or tarry.\nDo not give Imodium A-D to a child younger than 2 years old. Do not give this medicine to an older child or teenager without a doctor\'s advice.\nAsk a doctor or pharmacist if it is safe for you to use this medicine if you have:\na fever;\nmucus in your stools;\nliver disease; or\na heart rhythm disorder.\nAsk your doctor before using Imodium A-D to treat diarrhea caused by Clostridium difficile.\nAsk a doctor before using this medicine if you are pregnant or breastfeeding.\nYou should not breast-feed while you are using loperamide.\n','Avoid drinking tonic water. It can interact with loperamide and may cause serious heart problems.\nAvoid becoming dehydrated by drinking plenty of fluids. Avoid vigorous exercise or exposure to hot weather if you are dehydrated.\nImodium A-D liquid may contain alcohol. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(390,'impoyz','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nDo not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.\nDo not use Impoyz on broken or infected skin. Also avoid using this medicine in open wounds.\nWash your hands before and after using clobetasol, unless you are using the medicine to treat the skin on your hands.\nApply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.\nDo not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.\nIf you are treating the diaper area, do not use plastic pants or tight-fitting diapers.\nThis medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor\'s dosing instructions very carefully.\nIf you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.\nCall your doctor if your symptoms do not improve, or if they get worse.\nYou should not stop using clobetasol suddenly. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature away from moisture and heat. Keep from freezing.\nClobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.\n Detailed Impoyz dosage information\nWhat happens if I miss a dose?\nApply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\nHigh doses or long-term use of  Impoyz can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.\n','Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n Impoyz drug interactions (more detail)\nDoes Impoyz interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nworsening of your skin condition;\nredness, warmth, swelling, oozing, or severe irritation of any treated skin;\nblurred vision, tunnel vision, eye pain, or seeing halos around lights;\nhigh blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or\npossible signs of absorbing this medicine through your skin--weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.\nCommon side effects may include:\nburning, itching, swelling, or irritation of treated skin;\ndry or cracking skin;\nredness or crusting around your hair follicles;\nspider veins;\nstretch marks, thinning skin;\nrash or hives;\nacne; or\ntemporary hair loss.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Impoyz side effects (more detail)\n','Clobetasol is a highly potent steroid that helps reduce inflammation in the body.\nImpoyz (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.\nImpoyz may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use Impoyz if you are allergic to it.\nTell your doctor if you have ever had:\nany type of skin infection;\na skin reaction to any steroid medicine;\nliver disease; or\nan adrenal gland disorder.\nSteroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.\nIt is not known whether  Impoyz will harm an unborn baby. Tell your doctor if you are pregnant.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby\'s mouth.\nImpoyz is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.\nChildren can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.\n','Avoid applying  Impoyz to your face, underarms, or groin area.\nDo not use this medicine to treat any condition that has not been checked by your doctor.\nAvoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to.\n'),(391,'imuran','Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Imuran.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nWhen given for kidney transplant, Imuran is usually given right before or on the day of transplant. For rheumatoid arthritis, this medicine is taken on a daily basis.\nIt may take up to 8 weeks before your symptoms improve. Keep using Imuran as directed and tell your doctor if your symptoms have not improved after 12 weeks of use.\nTake with food if Imuran upsets your stomach.\nYou may not be able to continue taking other arthritis medications together with Imuran. Do not change your dose or dosing schedule without your doctor\'s advice.\nImuran affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Imuran dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your current medicines. Many drugs can affect Imuran, especially:\nallopurinol;\nfebuxostat; or\nribavirin.\nThis list is not complete and many other drugs may affect Imuran. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Imuran drug interactions (more detail)\nDoes Imuran interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nImuran may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.\nStop using Imuran and call your doctor right away if you have any of these symptoms of lymphoma:\nfever, swollen glands, body aches, night sweats, not feeling well;\npale skin, rash, easy bruising or bleeding;\ncold hands and feet, feeling light-headed or short of breath;\npain in your upper stomach that may spread to your shoulder; or\nfeeling full after eating only a small amount, weight loss.\nAlso call your doctor at once if you have:\nsigns of infection (fever, chills, weakness, flu symptoms, sore throat, cough, pain or burning when you urinate);\nsevere nausea, vomiting, or diarrhea;\neasy bruising, unusual bleeding;\nrapid heartbeats, shortness of breath;\npale skin, cold hands and feet; or\ndark urine, jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nnausea, diarrhea, stomach pain;\nhair loss; or\nskin rash.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Imuran side effects (more detail)\n','Imuran weakens your body\'s immune system, to help keep it from \"rejecting\" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.\nImuran is used to prevent your body from rejecting a transplanted kidney. This medicine is also used to treat symptoms of rheumatoid arthritis.\nImuran may also be used for purposes not listed in this medication guide.\n','Imuran may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn\'s disease or ulcerative colitis.\nBefore taking this medicine\nYou should not take  Imuran if you are allergic to Imuran.\nYou should not use Imuran to treat rheumatoid arthritis if you are pregnant. This medicine can harm an unborn baby. Use effective birth control to prevent pregnancy while using this medicine.\nImuran may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn\'s disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of lymphoma. Talk with your doctor about your own risk.\nWhile taking Imuran, you may have a higher risk of developing skin cancer. Ask your doctor about skin symptoms to watch for.\nTell your doctor if you have ever had:\nkidney disease, or a kidney transplant (if you are using Imuran for rheumatoid arthritis);\nany type of viral, bacterial, or fungal infection;\nliver disease; or\nchemotherapy with medications like cyclophosphamide, chlorambucil, melphalan, busulfan, and others.\nYou should not breast-feed while you are using Imuran.\n','Avoid sunlight or tanning beds. Imuran can increase your risk of developing skin cancer. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.\nAvoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\nDo not receive a \"live\" vaccine while using Imuran. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).\n'),(392,'incruse-ellipta','Usual Adult Dose for Chronic Obstructive Pulmonary Disease -- Maintenance:\n1 inhalation (62.5 mcg) orally once a day\nMaximum dose: 1 inhalation every 24 hours\nUse: Treatment of airflow obstruction in patients with COPD, including chronic bronchitis and/or emphysema\n Detailed Incruse Ellipta dosage information\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. Do not use more than once in a 24-hour period.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\natropine;\nmedicine to treat depression, anxiety, mood disorders, or mental illness;\ncold or allergy medicine (Benadryl and others);\nmedicine to treat Parkinson\'s disease;\nmedicine to treat stomach problems, motion sickness, or irritable bowel syndrome;\nmedicine to treat overactive bladder; or\nanother bronchodilator medication.\nThis list is not complete. Other drugs may interact with umeclidinium, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Incruse Ellipta drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Incruse Ellipta: hives, rash, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nwheezing, choking, or other breathing problems after using this medicine;\nblurred vision, nausea, vomiting, eye pain or redness, or seeing halos or bright colors around lights; or\npainful or difficult urination, or urinating more often.\nCommon Incruse Ellipta side effects may include:\ncold symptoms such as stuffy nose, sneezing, sore throat, cough;\nfast or irregular heartbeats;\nbruising, darkened skin;\nmouth pain, tooth pain;\nmuscle or joint pain;\nstomach pain; or\naltered sense of taste.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Incruse Ellipta side effects (more detail)\n','Incruse Ellipta (umeclidinium) is an anticholinergic that works by relaxing muscles in the airways to improve breathing.\nIncruse Ellipta is used to prevent airflow obstruction and reduce flare-ups in adults with COPD (chronic obstructive pulmonary disease, including bronchitis and emphysema.\nIncruse Ellipta is for use only in people with COPD and should not be used to treat asthma.\n','You should not use Incruse Ellipta if you are allergic to umeclidinium or have a severe allergy to milk proteins.\nIncruse Ellipta is not a rescue medicine. It will not work fast enough to treat a bronchospasm attack. Use only a fast acting inhalation medicine for an attack.\nSeek medical attention if your breathing problems do not improve, or if your symptoms get worse quickly.\nBefore taking this medicine\nYou should not use Incruse Ellipta if you are allergic to umeclidinium, or if you have:\na severe allergy to milk proteins.\nTo make sure Incruse Ellipta is safe for you, tell your doctor if you have:\nglaucoma;\nheart disease;\nan enlarged prostate; or\nurination problems.\nTell your doctor if you are pregnant or breastfeeding.\nIncruse Ellipta is not approved for use by anyone younger than 18 years old.\nHow should I use Incruse Ellipta?\nUse Incruse Ellipta exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nIncruse Ellipta is a powder that comes with a special inhaler device preloaded with blister packs containing measured doses of the medicine. The device opens and loads a blister of powdered medicine each time you use the inhaler. Follow the patient instructions provided with the inhaler device.\nThe usual dose is 1 inhalation per day. Use the medicine at the same time each day, and not more than once in a 24-hour period.\nIncruse Ellipta is not a rescue medicine. It will not work fast enough to treat a bronchospasm attack. Use only a fast acting inhalation medicine for an attack. Tell your doctor if any of your medicines seem to stop working as well in controlling your COPD.\nDo not stop using this medicine without your doctor\'s advice, even if you feel fine.\nDo not try to clean or take apart the inhaler device. Always use the new inhaler device provided with your refill.\nStore at room temperature away from moisture, heat, and light. Keep the inhaler device in the sealed foil tray until ready to start using it.\nThrow the inhaler away 6 weeks after opening, or when the dose indicator shows a zero (whichever comes first).\n','Do not use a second inhaled bronchodilator that contains aclidinium, arformoterol, indacaterol, olodaterol, salmeterol, tiotropium, or vilanterol.\nFollow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(393,'indapamide','Usual Adult Dose for Edema:\nInitial dose:  2.5 mg orally once a day.\nUsual Adult Dose for Hypertension:\nInitial dose:  1.25 mg orally once a day.\n Detailed Indapamide dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Tell your doctor about all your current medicines and any you start or stop using, especially:\ndigoxin, digitalis;\nlithium;\nblood pressure medication; or\nsteroids (prednisone and others).\nThis list is not complete. Other drugs may interact with indapamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Indapamide drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have signs of an electrolyte imbalance, such as:\ndrowsiness, lack of energy, feeling tired;\nleg cramps, muscle weakness or limp feeling;\nsevere weakness, loss of coordination, feeling unsteady;\nfast or irregular heartbeats, fluttering in your chest, feeling restless;\nnumbness or tingling;\nvomiting, constipation;\nheadache, confusion, slurred speech;\na light-headed feeling, like you might pass out;\ndry mouth, increased thirst; or\nlittle or no urinating.\nCommon side effects may include:\ndizziness;\nweakness, tiredness;\nback pain, muscle cramps;\nfeeling anxious or agitated;\nheadache; or\nrunny nose.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Indapamide side effects (more detail)\n','Indapamide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.\nIndapamide treats fluid retention (edema) in people with congestive heart failure.  indapamide is also used to treat high blood pressure (hypertension).\nIndapamide may also be used for purposes not listed in this medication guide.\n','You should not use this medicine if you are allergic to sulfa drugs or if you are unable to urinate.\nBefore taking this medicine\nYou should not use indapamide if you are allergic to it, or if:\nyou are unable to urinate; or\nyou are allergic to sulfa drugs.\nTo make sure indapamide is safe for you, tell your doctor if you have:\ncirrhosis or other liver disease;\nkidney disease;\nlow levels of potassium or sodium in your blood;\ngout;\ndiabetes;\nlupus; or\nif you are on a low-salt diet.\nIndapamide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether indapamide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using  indapamide.\nIndapamide is not approved for use by anyone younger than 18 years old.\nHow should I take indapamide?\nFollow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nIndapamide is usually taken once per day in the morning. Follow your doctor\'s dosing instructions very carefully.\nCall your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine, which can lead to severely low blood pressure or a serious electrolyte imbalance.\nWhile using indapamide, you may need frequent medical tests and blood pressure checks. Your blood and urine may both be tested if you have been vomiting or are dehydrated.\nIf you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include vomiting, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness.\n','Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor\'s instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.\n'),(394,'inderal','Take Inderal exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nAdults may take Inderal with or without food, but take it the same way each time.\nTake this medicine at the same time each day.\nDo not crush, chew, break, or open an extended-release capsule. Swallow it whole.\nYour blood pressure will need to be checked often.\nIf you need surgery, tell the surgeon ahead of time that you are using Inderal. You may need to stop using Inderal for a short time.\nDo not skip doses or stop using Inderal suddenly. Stopping suddenly may make your condition worse. Follow your doctor\'s instructions about tapering your dose.\nThis medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Inderal.\nIf you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.\nInderal is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.\nStore at room temperature away from moisture and heat.\n Detailed Inderal dosage information\nWhat happens if I miss a dose?\nFor regular (short-acting) propranolol: Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 4 hours away.\nFor extended-release propranolol (Inderal LA, InnoPran XL and others): Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 8 hours away.\nDo not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include slow or uneven heartbeats, dizziness, weakness, or fainting.\n','Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Inderal, especially:\na blood thinner - warfarin, Coumadin, Jantoven;\nan antidepressant - amitriptyline, clomipramine, desipramine, imipramine, and others;\ndrugs to treat high blood pressure or a prostate disorder - doxazosin, prazosin, terazosin;\nheart or blood pressure medicine - amiodarone, diltiazem, propafenone, quinidine, verapamil, and others;\nNSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or\nsteroid medicine-prednisone and others.\nThis list is not complete. Other drugs may interact with propranolol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Inderal drug interactions (more detail)\n','Get emergency medical help if you have any signs of an allergic reaction to Inderal: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nslow or uneven heartbeats;\na light-headed feeling, like you might pass out;\nwheezing or trouble breathing;\nshortness of breath (even with mild exertion), swelling, rapid weight gain;\nsudden weakness, vision problems, or loss of coordination;\ncold feeling in your hands and feet;\ndepression, confusion, hallucinations;\nliver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nlow blood sugar - headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;\nlow blood sugar in a baby - pale skin, blue or purple skin, sweating, fussiness, crying, not wanting to eat, feeling cold, drowsiness, weak or shallow breathing (breathing may stop for short periods), seizure (convulsions), or loss of consciousness; or\nsevere skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.\nCommon Inderal side effects may include:\nnausea, vomiting, diarrhea, constipation, stomach cramps;\ndecreased sex drive, impotence, or difficulty having an orgasm;\nsleep problems (insomnia); or\ntired feeling.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Inderal side effects (more detail)\n','Inderal (propranolol) is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).\nInderal is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches.\nInderal may also be used for purposes not listed in this medication guide.\n','You should not use Inderal if you have asthma, very slow heart beats, or a serious heart condition such as \"sick sinus syndrome\" or \"AV block\" (unless you have a pacemaker).\nBefore taking this medicine\nYou should not use Inderal if you are allergic to propranolol, or if you have:\nasthma;\nvery slow heart beats that have caused you to faint; or\na serious heart condition such as \"sick sinus syndrome\" or \"AV block\" (unless you have a pacemaker).\nTo make sure Inderal is safe for you, tell your doctor if you have:\na muscle disorder;\nasthma, bronchitis, emphysema, or other breathing disorders;\nlow blood sugar, or diabetes (propranolol can make it harder for you to tell when you have low blood sugar);\nslow heartbeats, low blood pressure;\ncongestive heart failure;\ndepression;\nliver or kidney disease;\na thyroid disorder;\npheochromocytoma (tumor of the adrenal gland); or\nproblems with circulation (such as Raynaud\'s syndrome).\nFDA pregnancy category C. It is not known whether Inderal will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.\nPropranolol can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\n Inderal pregnancy and breastfeeding warnings (more detail)\n','Avoid drinking alcohol. It may increase your blood levels of Inderal.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\n'),(395,'indocin','Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.\nSwallow the extended-release capsule whole and do not crush, chew, break, or open it.\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nYour dose needs may change if you switch to a different brand, strength, or form of  Indocin. Avoid medication errors by using only the form and strength your doctor prescribes.\nIf you use this medicine long-term, you may need frequent medical tests.\nIf you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.\nStore at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.\n Detailed Indocin dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness, stomach pain, or vomiting.\n','Ask your doctor before using Indocin if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.\nAsk a doctor or pharmacist before using Indocin with any other medications, especially:\ncyclosporine;\nlithium;\nmethotrexate;\nprobenecid;\nheart or blood pressure medication, including a diuretic or \"water pill\";\na blood thinner--warfarin, Coumadin, Jantoven; or\nother NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, meloxicam, and others.\nThis list is not complete. Other drugs may affect Indocin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Indocin drug interactions (more detail)\nDoes Indocin interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nGet emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.\nStop using Indocin and call your doctor at once if you have:\na skin rash, no matter how mild;\nchanges in your vision;\nheart problems--swelling, rapid weight gain, feeling short of breath;\nsigns of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea, vomiting, diarrhea, unusual tiredness, itching, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes);\nsigns of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nkidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or\nlow red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.\nCommon side effects may include:\nindigestion, nausea;\nheadache; or\ndizziness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Indocin side effects (more detail)\n','Indocin is a nonsteroidal anti-inflammatory drug (NSAID).\nIndocin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. This medicine is also used to treat shoulder pain caused by bursitis or tendinitis.\nExtended-release Indocin (Indocin SR) should not be used to treat gouty arthritis.\nIndocin may also be used for purposes not listed in this medication guide.\n','Indocin can increase your risk of fatal heart attack or stroke, even if you don\'t have any risk factors. Do not use  Indocin just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nIndocin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.\nBefore taking this medicine\nIndocin can increase your risk of fatal heart attack or stroke, even if you don\'t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nIndocin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.\nYou should not use Indocin if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.\nTell your doctor if you have ever had:\nheart disease, high blood pressure;\na heart attack, stroke, or blood clot;\nfluid retention;\nbleeding problems;\nstomach ulcers or bleeding;\nasthma;\nliver or kidney disease; or\nif you smoke.\nIf you are pregnant, you should not take Indocin unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.\nThis medicine may temporarily affect fertility (ability to have children) in women.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nIndocin is not approved for use by anyone younger than 14 years old.\n','Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding.\nAvoid taking aspirin unless your doctor tells you to.\nAsk a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to Indocin (such as aspirin, ibuprofen, ketoprofen, or naproxen).\n'),(396,'indomethacin','Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.\nSwallow the extended-release capsule whole and do not crush, chew, break, or open it.\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nYour dose needs may change if you switch to a different brand, strength, or form of  indomethacin. Avoid medication errors by using only the form and strength your doctor prescribes.\nIf you use this medicine long-term, you may need frequent medical tests.\nIf you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.\nStore at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.\n Detailed Indomethacin dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness, stomach pain, or vomiting.\n','Ask your doctor before using indomethacin if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.\nAsk a doctor or pharmacist before using indomethacin with any other medications, especially:\ncyclosporine;\nlithium;\nmethotrexate;\nprobenecid;\nheart or blood pressure medication, including a diuretic or \"water pill\";\na blood thinner--warfarin, Coumadin, Jantoven; or\nother NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, meloxicam, and others.\nThis list is not complete. Other drugs may affect indomethacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Indomethacin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nGet emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.\nStop using indomethacin and call your doctor at once if you have:\na skin rash, no matter how mild;\nchanges in your vision;\nheart problems--swelling, rapid weight gain, feeling short of breath;\nsigns of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea, vomiting, diarrhea, unusual tiredness, itching, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes);\nsigns of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nkidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or\nlow red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.\nCommon side effects may include:\nindigestion, nausea;\nheadache; or\ndizziness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Indomethacin side effects (more detail)\n','Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID).\nIndomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. Indomethacin is also used to treat shoulder pain caused by bursitis or tendinitis.\nExtended-release indomethacin (Indocin SR) should not be used to treat gouty arthritis.\nIndomethacin may also be used for purposes not listed in this medication guide.\n','Indomethacin can increase your risk of fatal heart attack or stroke, even if you don\'t have any risk factors. Do not use  indomethacin just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nIndomethacin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using indomethacin, especially in older adults.\nBefore taking this medicine\nIndomethacin can increase your risk of fatal heart attack or stroke, even if you don\'t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nIndomethacin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using indomethacin, especially in older adults.\nYou should not use indomethacin if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.\nTell your doctor if you have ever had:\nheart disease, high blood pressure;\na heart attack, stroke, or blood clot;\nfluid retention;\nbleeding problems;\nstomach ulcers or bleeding;\nasthma;\nliver or kidney disease; or\nif you smoke.\nIf you are pregnant, you should not take indomethacin unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.\nThis medicine may temporarily affect fertility (ability to have children) in women.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nIndomethacin is not approved for use by anyone younger than 14 years old.\n','Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding.\nAvoid taking aspirin unless your doctor tells you to.\nAsk a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to indomethacin (such as aspirin, ibuprofen, ketoprofen, or naproxen).\n'),(397,'infliximab','Before you start treatment with infliximab, your doctor may perform tests to make sure you do not have tuberculosis or other infections.\nInfliximab is given as an infusion into a vein. A healthcare provider will give you this injection.\n infliximab must be given slowly, and the infusion can take at least 2 hours to complete.\nYou may be watched closely after receiving infliximab, to make sure the medicine has not caused any serious side effects.\nInfliximab affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis, and you may need frequent TB tests.\nSerious infections may be more likely in older adults.\nIf you need surgery, tell the surgeon ahead of time that you are using infliximab.\nIf you\'ve ever had hepatitis B, using infliximab can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.\n Detailed Infliximab dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your infliximab injection.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\nabatacept;\nanakinra;\ntocilizumab;\nany \"biologic\" medications to treat your condition--adalimumab, certolizumab, etanercept, golimumab, natalizumab, rituximab, and others; or\nany other medicines to treat Crohn\'s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis.\nThis list is not complete. Other drugs may affect infliximab, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Infliximab drug interactions (more detail)\nDoes Infliximab interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; fever, chills, severe dizziness; swelling of your face, lips, tongue, or throat.\nSome side effects may occur during the injection. Tell your caregiver if you feel dizzy, nauseated, light-headed, itchy or tingly, short of breath, or have a headache, fever, chills, muscle or joint pain, pain or tightness in your throat, chest pain, or trouble swallowing during the injection. Infusion reactions may also occur within 1 or 2 hours after injection.\nSerious and sometimes fatal infections may occur during treatment with infliximab. Call your doctor right away if you have signs of infection such as: fever, extreme tiredness, flu symptoms, cough, or skin symptoms (pain, warmth, or redness).\nAlso call your doctor if you have:\nskin changes, new growths on the skin;\npale skin, easy bruising or bleeding;\ndelayed allergic reaction (up to 12 days after receiving infliximab)--fever, sore throat, trouble swallowing, headache, joint or muscle pain, skin rash, or swelling in your face or hands;\nliver problems--right-sided upper stomach pain, loss of appetite, yellowing of your skin or eyes, and not feeling well;\nlupus-like syndrome--joint pain or swelling, chest discomfort, feeling short of breath, skin rash on your cheeks or arms (worsens in sunlight);\nnerve problems--numbness or tingling, problems with vision, weakness in your arms or legs, seizure;\nnew or worsening psoriasis--skin redness or scaly patches, raised bumps filled with pus;\nsigns of heart failure--shortness of breath with swelling of your ankles or feet, rapid weight gain;\nsigns of a stroke--sudden numbness or weakness, trouble speaking or understanding what is said to you, problems with vision or balance, severe headache;\nsigns of lymphoma--fever, night sweats, weight loss, stomach pain or swelling, chest pain, cough, trouble breathing, swollen glands (in your neck, armpits, or groin); or\nsigns of tuberculosis--fever, cough, night sweats, loss of appetite, weight loss, feeling constantly tired.\nSerious infections may be more likely in adults who are 65 years or older.\nCommon side effects may include:\nstuffy nose, sinus pain;\nfever, chills, sore throat;\ncough, chest pain, shortness of breath;\nhigh or low blood pressure;\nheadache, feeling light-headed;\nrash, itching; or\nstomach pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Infliximab side effects (more detail)\n','Infliximab is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and severe or disabling plaque psoriasis in adults.\nInfliximab is also used to treat ulcerative colitis or Crohn\'s disease in adults and children at least 6 years old.\nInfliximab is often used when other medicines have not been effective.\nInfliximab may also be used for purposes not listed in this medication guide.\n','Using infliximab may increase your risk of developing certain types of cancer, including a rare fast-growing type of lymphoma that can be fatal. Ask your doctor about your specific risk.\nInfliximab affects your immune system. You may get infections more easily, even serious or fatal infections. Before you start using infliximab, your doctor may perform tests to make sure you do not have certain infections.\nCall your doctor if you have a fever, tiredness, flu symptoms, cough, or skin sores.\nBefore taking this medicine\nYou should not be treated with infliximab if you are allergic to it.\nTell your doctor if you have ever had tuberculosis (TB) or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.\nTell your doctor if you have ever had:\nan active infection (fever, cough, flu symptoms, open sores or skin wounds);\nheart failure or other heart problems;\ndiabetes;\na weak immune system;\nliver failure, hepatitis B, or other liver problems;\nchronic obstructive pulmonary disease (COPD);\nheart problems;\ncancer;\nseizures;\nnumbness or tingling anywhere in your body;\na nerve-muscle disorder, such as multiple sclerosis or Guillain-Barré syndrome;\nphototherapy for psoriasis;\nvaccination with BCG (Bacille Calmette-Guérin); or\nif you are scheduled to receive any vaccines.\nMake sure your child is current on all vaccines before he or she starts treatment with infliximab.\nInfliximab may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn\'s disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of lymphoma. Talk with your doctor about your own risk.\nInfliximab may cause other types of cancer, such as skin cancer or cancer of the cervix. Ask your doctor about this risk.\nIf you use infliximab while you are pregnant, make sure any doctor caring for your new baby knows that you used the medicine during pregnancy. Being exposed to infliximab in the womb could affect your baby\'s vaccination schedule during the first 6 months of life.\nYou should not breastfeed while you are receiving infliximab.\nInfliximab is not for use in children younger than 6 years old.\n','Avoid activities that may increase your risk of bleeding injury.\nDo not receive a \"live\" vaccine while using infliximab, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).\n'),(398,'ingrezza','Usual Adult Dose for Tardive Dyskinesia:\n-Initial Dose: 40 mg orally once a day\n-Maintenance Dose: Increase to 80 mg orally once a day after one week at the initial dose; however, continuation of the initial dose may be considered for some patients.\nComments: Administer with or without food.\nUse: Treatment of tardive dyskinesia.\n Detailed Ingrezza dosage information\n','Other drugs may interact with valbenazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ingrezza drug interactions (more detail)\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOther drugs may interact with valbenazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n','Get emergency medical help if you have signs of an allergic reaction to Ingrezza: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nextreme drowsiness;\nfast, slow, or uneven heartbeats;\npounding heartbeats or fluttering in your chest;\nshortness of breath; or\na light-headed feeling, like you might pass out.\nCommon Ingrezza side effects may include:\nheadache, dizziness, drowsiness;\nproblems with balance or coordination;\ndry mouth;\nfeeling restless;\nconstipation; or\nblurred vision.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ingrezza side effects (more detail)\n','Ingrezza (valbenazine) blocks certain chemicals in the body that may be involved with involuntary muscle movement.\nIngrezza is used to treat symptoms of tardive dyskinesia, a nervous system disorder. Tardive dyskinesia causes repetitive uncontrolled muscle movements, usually in the face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement).\nIngrezza is not a permanent cure for this condition.\n','Do not breast-feed while using Ingrezza and for at least 5 days after your last dose.\nBefore taking this medicine\nYou should not use Ingrezza if you are allergic to valbenazine.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nheart disease;\nlong QT syndrome or other heart rhythm disorder;\ncongestive heart failure;\na heart attack;\nliver disease; or\nkidney disease.\nIt is not known whether Ingrezza will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nDo not breast-feed while using this medicine and for at least 5 days after your last dose.\nIngrezza is not approved for use by anyone younger than 18 years old.\nHow should I take Ingrezza?\nTake Ingrezza exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYou may take Ingrezza with or without food.\nYour heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).\nDo not stop taking this medicine without first asking your doctor.\nStore at room temperature away from moisture and heat.\n','Valbenazine may impair your thinking or reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\n'),(399,'injectafer','Usual Adult Dose for Iron Deficiency Anemia:\nPatients weighing 50 kg or more: Two doses of 750 mg via slow IV push or infusion separated by at least 7 days\nAlternatively, for patients weighing 50 kg or more: 15 mg/kg to a maximum of 1000 mg may be administered as a single-dose treatment course\nPatients weighing less than 50 kg: Two doses of 15 mg/kg via slow IV push or infusion separated by at least 7 days\nMaximum dose: Total cumulative dose should not exceed 1500 mg of iron per course\nComments:\n-The dosage is expressed in mg of elemental iron.\n-Treatment may be repeated if iron deficiency anemia recurs\nUse: Treatment of iron deficiency anemia in adults with an intolerance or unsatisfactory response to oral iron and in adults with non-dialysis dependent chronic kidney disease\n Detailed Injectafer dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Injectafer injection.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include weakness, joint problems, and problems with balance or walking.\n','Other drugs may interact with ferric carboxymaltose, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Injectafer drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Injectafer: hives; feeling light-headed; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nincreased blood pressure - severe headache, pounding in your neck or ears, dizziness, nausea;\nlow levels of phosphorus in your blood - confusion, bone pain, muscle weakness; or\nhigh levels of iron stored in your body - metallic taste in the mouth, bloody or tarry stools, vomiting blood, severe shortness of breath, chest pain, pale skin, blue lips or fingernails, loss of consciousness, or seizure (convulsions).\nCommon Injectafer side effects may include:\nnausea;\ndizziness;\nhigh blood pressure;\nflushing (warmth, redness, or tingly feeling); or\nlow phosphorus levels.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Injectafer side effects (more detail)\n','Injectafer (ferric carboxymaltose) is an injectable iron replacement product. You normally get iron from the foods you eat. Iron helps your body produce red blood cells that carry oxygen through your blood to tissues and organs.\nInjectafer is used in adults to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).\nInjectafer is usually given after oral (taken by mouth) iron replacement medicines have been tried without success.\n','You should not use Injectafer if you have iron overload disorder, or anemia that is not caused by iron deficiency.\nBefore taking this medicine\nYou should not use Injectafer if you are allergic to ferric carboxymaltose, or if you have:\niron overload disorder (hemochromatosis, hemosiderosis); or\nanemia that is not caused by iron deficiency.\nTo make sure Injectafer is safe for you, tell your doctor if you have:\nliver disease; or\nhigh blood pressure.\nIt is not known whether Injectafer will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nFerric carboxymaltose can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nHow is Injectafer given?\nInjectafer is injected into a vein through an IV. A healthcare provider will give you this injection.\nInjectafer is usually given in two doses, 7 days apart, or given as a single dose. Your doctor will determine whether you need a repeat course.\nTell your caregivers if you feel any burning, pain, or swelling around the IV needle when Injectafer is injected.\nYou will be watched closely for at least 30 minutes after receiving Injectafer, to make sure you do not have an allergic reaction to the medication.\nTell your doctor if you have any changes in weight. Injectafer doses are based on weight, and any changes may affect the dose.\nTo be sure this medicine is helping your condition, you may need frequent blood tests. You may not notice any change in your symptoms, but your blood work will help your doctor determine how long to treat you with Injectafer.\n','Iron is contained in many vitamin or mineral supplements. Taking certain products together can cause you to get too much iron. Avoid taking any vitamin or mineral supplement your doctor has not recommended.\n'),(400,'inlyta','Usual Adult Dose for Renal Cell Carcinoma:\nInitial dose: 5 mg orally twice a day\nMaintenance dose: Increase or decrease dose based on individual safety and tolerability\nDose range: 2 to 10 mg twice a day\nComments: Doses should be taken approximately 12 hours apart.\nUse: For the treatment of advanced renal cell carcinoma after the failure of 1 prior systemic therapy.\n Detailed Inlyta dosage information\nWhat happens if I miss a dose?\nSkip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may interact with axitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Inlyta drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Inlyta: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome people taking Inlyta have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nAlso call your doctor at once if you have:\nchest pain or pressure, pain spreading to your jaw or shoulder, trouble breathing;\nsudden numbness or weakness, problems with vision or speech;\nheadache, confusion, thinking problems, seizure (convulsions);\na light-headed feeling, like you might pass out;\neasy bruising, unusual bleeding, purple or red spots under your skin;\nheavy menstrual bleeding;\nany bleeding that will not stop;\npink or brown urine;\nheart problems - swelling, rapid weight gain, feeling short of breath;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or\nsigns of a thyroid problem - sudden weight gain or loss, feeling very weak or tired, muscle pain, feeling hot or cold, hair loss, hoarse or deepened voice.\nCommon Inlyta side effects may include:\nnausea, vomiting, diarrhea, constipation;\nrash, itching, redness, and peeling skin on your hands or feet;\nfeeling weak or tired;\nincreased blood pressure;\ndecreased appetite, weight loss; or\nhoarse voice.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Inlyta side effects (more detail)\n','Inlyta (axitinib) is a prescription medicine that interferes with the growth of some cancer cells.\nInlyta is used to treat advanced kidney cancer (advanced renal cell carcinoma).\nInlyta is sometimes given after at least one other cancer treatment did not work or has stopped working.\nIt is not known if Inlyta is safe and effective in children.\n','Do not use Inlyta if you are pregnant. It could harm the unborn baby. Use birth control to prevent pregnancy while you are receiving this medicine, whether you are a man or a woman. Inlyta use by either parent may cause birth defects or miscarriage.\nAxitinib can increase your risk of serious bleeding. Stop using Inlyta and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.\nSome people taking this medicine have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nInlyta is usually taken once every 12 hours. It should be taken at evenly spaced intervals. Follow your doctor\'s instructions.\nTo be sure this medication is not causing harmful effects, your kidney, thyroid, and liver function will need to be tested. Your blood pressure will also need to be checked often. Visit your doctor regularly.\nBefore taking this medicine\nYou should not use Inlyta if you are allergic to axitinib.\nTo make sure Inlyta is safe for you, tell your doctor if you have:\na perforation (a hole or tear) in your stomach or intestines;\nbleeding problems, or a wound that has not healed;\na heart attack, heart failure, stroke, or blood clot.\nhigh blood pressure;\nliver disease; or\na thyroid disorder.\nYou may need to have a negative pregnancy test before starting this treatment.\nBoth men and women using this medicine should use effective birth control to prevent pregnancy. Axitinib can cause harm an unborn baby if the mother or father is using this medicine.\nKeep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Inlyta.\nThis medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because axitinib can harm an unborn baby.\nIt is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 2 weeks after your last dose.\nHow should I take Inlyta?\nTake Inlyta exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nInlyta should be taken at evenly spaced intervals, usually once every 12 hours.\nTake this medicine with a full glass of water. You may take this medicine with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nIf you vomit shortly after taking Inlyta, do not take another dose. Wait until your next scheduled dose time to take the medicine again.\nYour blood pressure will need to be checked often. You may also need frequent medical tests.\nIf you need surgery, tell your surgeon you currently use Inlyta. You will need to stop using the medicine at least 24 hours before a planned surgery.\nStore at room temperature away from moisture and heat.\n','Grapefruit may interact with axitinib and lead to unwanted side effects. Avoid the use of grapefruit products.\n'),(401,'insulin','Use insulin exactly as directed. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nRegular insulin is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself. Regular insulin must not be given with a pump. Do not inject this medicine into a vein or a muscle.\nRead and carefully follow any Instructions for Use provided with your medicine. Do not use insulin if you don\'t understand all instructions for proper use. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.\nYour care provider will show you where on your body to inject this medicine. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nDo not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nAfter using regular insulin, you should eat a meal within 30 minutes.\nNever share a syringe with another person, even if the needle has been changed. Sharing syringes can allow infections or disease to pass from one person to another.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, medications, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nInsulin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nIn case of emergency, wear or carry medical identification to let others know you have diabetes.\nKeep this medicine in its original container protected from heat and light. Do not freeze or store near the cooling element in a refrigerator. Throw away any insulin that has been frozen.\nStoring unopened (not in use) pens of vials:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within the number of days shown in your Instructions for Use.\nStoring opened (in use) pens or vials:\nStore at room temperature and use within the number of days shown in your Instructions for Use.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n Detailed Insulin regular dosage information\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nKeep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, or increase/decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Insulin regular drug interactions (more detail)\n','Get emergency medical help if you have signs of insulin allergy: redness, swelling, sweating, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nlow potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon insulin side effects may include:\nlow blood sugar;\nswelling in your hands or feet;\nweight gain; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Insulin regular side effects (more detail)\n','Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Regular insulin is short-acting and starts to work within 30 minutes after injection, peaks in 2 to 3 hours, and keeps working for up to 8 hours.\nRegular insulin is used to improve blood sugar control in adults and children with diabetes mellitus.\nInsulin regular may be used for type 1 or type 2 diabetes.\n','You should not use insulin if you are having an episode of hypoglycemia (low blood sugar).\nHypoglycemia, or low blood sugar, is the most common side effect of insulin. Symptoms include headache, hunger, dizziness, sweating, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets with you in case you have low blood sugar.\nBefore taking this medicine\nYou should not use insulin regular if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).\nRegular insulin is not approved for use by anyone younger than 2 years old. This medicine should not be used to treat type 2 diabetes in a child of any age.\nTell your doctor if you have ever had:\nliver or kidney disease; or\nheart failure.\nTaking certain oral diabetes medicines while using insulin may increase your risk of serious heart problems. Tell your doctor if you also take medicine that contains pioglitazone or rosiglitazone.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using regular insulin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Do not change the brand of insulin or syringe you are using without first talking to your doctor or pharmacist. Some brands are interchangeable, while others are not. Your doctor and/or pharmacist know which brands can be substituted for one another.\nInsulin can cause low blood sugar. Avoid driving or operating machinery until you know how this medicine will affect you.\nAvoid medication errors by always checking the medicine label before injecting your dose.\nAvoid drinking alcohol. It can interfere with your diabetes treatment.\n'),(402,'insulin-detemir','Use insulin detemir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nInsulin detemir is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an insulin detemir injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.\nYour healthcare provider will show you where on your body to inject insulin detemir. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nDo not inject insulin detemir into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nIf you use insulin detemir once daily, use the injection at your evening meal or at bedtime. If you use the medicine twice daily, use your evening dose at least 12 hours after your morning dose.\nYour doctor may want you to also use a short-acting insulin. Always inject your insulins separately. Insulin detemir must not be given with an insulin pump, or mixed with other insulins. Do not inject into a vein or a muscle.\nIf you use an injection pen, use only the injection pen that comes with insulin detemir. Attach a new needle before each use. Do not transfer the insulin from the pen into a syringe.\nNever share an injection pen or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nInsulin detemir is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nKeep insulin detemir in its original container protected from heat and light. Do not draw insulin from a vial into a syringe until you are ready to give an injection. Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen.\nStoring unopened (not in use) insulin detemir:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within 42 days.\nStoring opened (in use) insulin detemir:\nStore the vial in a refrigerator or at room temperature and use within 42 days.\nStore the injection pen at room temperature (do not refrigerate) and use within 42 days. Do not store the injection pen with a needle attached.\nIn case of emergency, wear or carry medical identification to let others know you have diabetes.\n Detailed Insulin detemir dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose. Keep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products.\n Insulin detemir drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergy to insulin detemir: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nfluid retention - weight gain, swelling in your hands or feet, feeling short of breath; or\nlow potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon insulin detemir side effects may include:\nlow blood sugar;\nweight gain;\nswelling in your hands and feet;\nrash, itching; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Insulin detemir side effects (more detail)\n','Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin detemir is a man-made long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.\nInsulin detemir is used to improve blood sugar control in people with diabetes mellitus.\nInsulin detemir is for use in adults and children at least 2 years old.\nInsulin detemir is not to be used to treat diabetic ketoacidosis.\n','Never share an injection pen or syringe with another person, even if the needle has been changed.\nBefore taking this medicine\nYou should not use insulin detemir if you are allergic to it. Do not use during an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment).\nTo make sure insulin detemir is safe for you, tell your doctor if you have ever had:\nlow levels of potassium in your blood (hypokalemia); or\nliver or kidney disease.\nTell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin detemir may increase your risk of serious heart problems.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using insulin detemir if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Insulin can cause low blood sugar. Avoid driving or operating machinery until you know how insulin detemir will affect you.\nAvoid medication errors by always checking the medicine label before injecting your insulin.\nAvoid drinking alcohol.\n'),(403,'insulin-glargine','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nInsulin glargine is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.\nInsulin glargine must not be given with an insulin pump, or mixed with other insulins. Do not inject insulin glargine into a vein or a muscle.\nDo not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nRead and carefully follow any Instructions for Use provided with your medicine. Do not use insulin glargine if you don\'t understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.\nThe Toujeo brand of insulin glargine contains 3 times as much insulin per milliliter (mL) as the Lantus or Basaglar brands. There are 300 units of insulin in 1 mL of Toujeo, and 100 units in 1 mL of Lantus or Basaglar.\nIf there are any changes in the brand, strength, or type of insulin you use, your dosage needs may change.\nIf you use an injection pen, use only the injection pen that comes with insulin glargine. Attach a new needle before each use. Do not transfer the insulin from the pen into a syringe.\nNever share an injection pen or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nKeep this medicine in its original container protected from heat and light. Do not draw insulin from a vial into a syringe until you are ready to give an injection. Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen.\nStoring unopened (not in use) Basaglar or Lantus:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within 28 days.\nStoring unopened (not in use) Toujeo:\nRefrigerate and use until expiration date.\nStoring opened (in use) Basaglar or Lantus:\nStore the vial in a refrigerator or at room temperature and use within 28 days.\nStore the injection pen at room temperature (do not refrigerate) and use within 28 days.\nStoring opened (in use) Toujeo:\nStore the injection pen at room temperature (do not refrigerate) and use within 42 days.\nDo not store an injection pen with the needle attached.\nDo not use the medicine if it looks cloudy, has changed colors, or has any particles in it. Call your pharmacist for new medicine.\nWear a diabetes medical alert tag in case of emergency. Any medical care provider who treats you should know that you have diabetes.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n Detailed Insulin glargine dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose of insulin glargine. You should not use more than one dose in a 24-hour period unless your doctor tells you to.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products.\n Insulin glargine drug interactions (more detail)\n','Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nrapid weight gain, swelling in your feet or ankles;\nshortness of breath; or\nlow potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon side effects may include:\nlow blood sugar;\nitching, mild skin rash; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Insulin glargine side effects (more detail)\n','Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.\nInsulin glargine is used to improve blood sugar control in people with diabetes mellitus.  insulin glargine is for use in adults with type 1 or type 2 diabetes, and in children at least 6 years old with type 1 diabetes.\nSome brands of this medicine are for use only in adults. Carefully follow all instructions for the brand of insulin glargine you are using.\nInsulin glargine may also be used for purposes not listed in this medication guide.\n','Never share an injection pen or syringe with another person, even if the needle has been changed.\nBefore taking this medicine\nYou should not use  insulin glargine if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment).\nInsulin glargine is not approved for use by anyone younger than 6 years old, and some brands are for use only in adults. Do not use this medicine to treat type 2 diabetes in a child of any age.\nTell your doctor if you have ever had:\nliver or kidney disease; or\nheart failure or other heart problems.\nTell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using insulin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Avoid driving or hazardous activity until you know how  insulin glargine will affect you. Your reactions could be impaired.\nAvoid medication errors by always checking the medicine label before injecting your insulin.\nAvoid drinking alcohol. It can cause low blood sugar and may interfere with your diabetes treatment.\n'),(404,'insulin-lispro','Use Insulin lispro exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nInsulin lispro is injected under the skin with a syringe and needle, an injection pen, or with an infusion pump. A healthcare provider will teach you how to properly use insulin lispro by yourself.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nPrepare your injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors or has particles in it. Call your pharmacist for new medicine.\nAdmelog or HumaLOG are given within 15 minutes before a meal, or right after eating. Lyumjev is given at the start of a meal or within 20 minutes after eating.\nYour healthcare provider will show you where on your body to inject insulin lispro. Use a different place each time you give an injection. Do not inject into the same place two times in a row. Do not inject into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nConcentrated insulin lispro (200 units) must not be given with an insulin pump, or mixed with other insulins. Do not transfer insulin lispro from an injection pen to a syringe or a severe overdose could occur.\nNever share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nKeep insulin lispro in its original container protected from heat and light. Do not freeze insulin lispro or store it near the cooling element in a refrigerator. Throw away any insulin lispro that has been frozen.\nStoring unopened (not in use) insulin lispro:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within 28 days.\nStoring opened (in use) insulin lispro:\nStore the vial in a refrigerator or at room temperature and use within 28 days.\nStore the cartridge or injection pen (without a needle attached) at room temperature and use within 28 days.\nUse a needle and syringe only once and place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n Detailed Insulin lispro dosage information\nWhat happens if I miss a dose?\nSince insulin lispro is used with meals, you may not be on a timed dosing schedule. Whenever you use insulin lispro, follow the directions for your specific brand about whether to use the medicine before of after you eat. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products.\n Insulin lispro drug interactions (more detail)\n','Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nweight gain, swelling in your hands or feet, feeling short of breath;\nlow blood sugar - headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or\nlow potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon Insulin lispro side effects may include:\nlow blood sugar;\nweight gain;\nswelling in your hands or feet;\nitching; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Insulin lispro side effects (more detail)\n','Insulin Lispro is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin lispro is a fast-acting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours.\nInsulin lispro is used to improve blood sugar control in adults and children with diabetes mellitus.\nAdmelog and HumaLOG are used to treat type 2 diabetes in adults, or type 1 diabetes in adults and children who are at least 3 years old.\nLyumjev is not approved for use by anyone younger than 18 years old.\n','Do not share your Insulin lispro with another person. This includes any pens, cartridge devices, needles, or syringes, even if the needle has been changed. Sharing may pass infections from one person to another. This includes infections you may not know you have.\nLow blood sugar may happen with insulin lispro. Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death.\nLow blood potassium may also happen with insulin lispro. If not treated, this can lead to a heartbeat that is not normal, very bad breathing problems, and sometimes death.\nIt may be harder to control blood sugar during times of stress such as fever, infection, injury, or surgery. A change in physical activity, exercise, or diet may also affect blood sugar.\nDo not drive if your blood sugar has been low. There is a greater chance of you having a crash.\nTalk with your doctor before you drink alcohol or take products that have alcohol in them.\nBefore taking this medicine\nYou should not use insulin lispro if you are allergic to it, or if you are having an episode of hypoglycemia (low blood sugar).\nInsulin lispro should not be given to a child younger than 3 years old. Insulin lispro should not be used to treat type 2 diabetes in a child of any age.\nTo make sure Insulin lispro is safe for you, tell your doctor if you have ever had:\nliver or kidney disease;\nheart problems; or\nlow levels of potassium in your blood (hypokalemia).\nTell your doctor if you also take medicine that contains pioglitazone or rosiglitazone. Taking certain oral diabetes medicines while you are using insulin lispro may increase your risk of serious heart problems.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using insulin lispro if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Insulin can cause low blood sugar. Avoid driving or operating machinery until you know how insulin lispro will affect you.\nAvoid medication errors by always checking the medicine label before injecting your insulin lispro.\nAvoid drinking alcohol.\n'),(405,'insulin-regular','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nRegular insulin is injected under the skin. A healthcare provider can teach you how to properly use the medication by yourself. Regular insulin must not be given with an insulin pump. Do not inject regular insulin into a vein or a muscle.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.\nPrepare your injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.\nYour care provider will show you where on your body to inject insulin. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nDo not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.\nAfter using regular insulin, you should eat a meal within 30 minutes.\nNever share a syringe with another person, even if the needle has been changed. Sharing syringes can allow infections or disease to pass from one person to another.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nInsulin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nIn case of emergency, wear or carry medical identification to let others know you have diabetes.\nKeep this medicine in its original container protected from heat and light. Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen.\nStoring unopened (not in use) regular insulin:\nRefrigerate and use until expiration date; or\nStore at room temperature and use within the number of days shown in your Instructions for Use.\nStoring opened (in use) regular insulin:\nStore at room temperature and use within the number of days shown in your Instructions for Use.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n Detailed Insulin regular dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nKeep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.\n','Many other medicines can affect your blood sugar, or increase/decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Insulin regular drug interactions (more detail)\n','Get emergency medical help if you have signs of insulin allergy: redness, swelling, sweating, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.\nCall your doctor at once if you have:\nlow potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nCommon side effects may include:\nlow blood sugar;\nswelling in your hands or feet;\nweight gain; or\nthickening or hollowing of the skin where you injected the medicine.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Insulin regular side effects (more detail)\n','Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Regular insulin is a short-acting insulin that starts to work within 30 minutes after injection, peaks in 2 to 3 hours, and keeps working for up to 8 hours.\nRegular insulin is used to improve blood sugar control in adults and children with diabetes mellitus.  insulin regular may be used for type 1 or type 2 diabetes.\nRegular insulin may also be used for purposes not listed in this medication guide.\n','You should not use insulin if you are having an episode of hypoglycemia (low blood sugar).\nBefore taking this medicine\nYou should not use  insulin regular if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).\nRegular insulin is not approved for use by anyone younger than 2 years old. Regular insulin should not be used to treat type 2 diabetes in a child of any age.\nTell your doctor if you have ever had:\nliver or kidney disease; or\nheart failure.\nTaking certain oral diabetes medicines while using insulin may increase your risk of serious heart problems. Tell your doctor if you also take medicine that contains pioglitazone or rosiglitazone.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using insulin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\n','Do not change the brand of insulin or syringe you are using without first talking to your doctor or pharmacist. Some brands of insulin and syringes are interchangeable, while others are not. Your doctor and/or pharmacist know which brands can be substituted for one another.\nInsulin can cause low blood sugar. Avoid driving or operating machinery until you know how  insulin regular will affect you.\nAvoid medication errors by always checking the medicine label before injecting your insulin.\nAvoid drinking alcohol. It can interfere with your diabetes treatment.\n'),(406,'intuniv','Usual Pediatric Dose for Attention Deficit Disorder:\n6 YEARS TO LESS THAN 18 YEARS:\nInitial dose: 1 mg orally once a day, either in the morning or evening, at approximately the same time each day; may adjust in increments of no more than 1 mg/week.\nRecommended target dose: 0.05 to 0.12 mg/kg/day (total daily dose between 1 and 7 mg) once a day, depending on clinical response and tolerability\nMaximum dose: 6 to 12 years: Doses above 4 mg/day have not been evaluated; 13 to 17 years: Doses above 7 mg/day have not been evaluated.\nComments: Attention Deficit Hyperactivity Disorder (ADHD) may require treatment for an extended period of time; healthcare providers should periodically reevaluate treatment and adjust dose as needed.\nUse: Treatment of ADHD as monotherapy and as adjunctive therapy to stimulant medications.\n Detailed Intuniv dosage information\nWhat happens if I miss a dose?\nAvoid taking Intuniv with high-fat foods, or your body could absorb the medicine too quickly.\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nCall your doctor for instructions if you miss more than 2 doses in a row.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness, slow heart rate, and feeling like you might pass out.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nUsing Intuniv with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.\nTell your doctor about all your other medicines. Some may affect Intuniv, especially:\nketoconazole;\na barbiturate, such as phenobarbital;\nblood pressure medications;\nmedicine to treat mental illness; or\na sedative, such as Valium or Xanax.\nThis list is not complete. Other drugs may interact with guanfacine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Intuniv drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Intuniv: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nanxiety, nervousness;\nhallucinations (especially in children);\nsevere drowsiness;\nslow heartbeats; or\na light-headed feeling, like you might pass out;\nIf you stop taking Intuniv, tell your doctor if you have headaches, confusion, rapid heartbeats, tremors, increased blood pressure, or if you feel nervous or agitated. If left untreated, these symptoms could lead to very high blood pressure, vision problems, or seizures.\nCommon Intuniv side effects may include:\ndizziness, drowsiness;\nlow blood pressure, slow heartbeats;\nfeeling tired or irritable;\ntrouble sleeping;\ndry mouth; or\nstomach pain, nausea, constipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Intuniv side effects (more detail)\n','Intuniv (guanfacine) reduces nerve impulses in your heart and blood vessels. Intuniv works by relaxing blood vessels, which lowers blood pressure and improves blood flow.\nIntuniv is a prescription medicine used to treat attention deficit hyperactivity disorder (ADHD) in children who are at least 6 years old.\nIntuniv is a long acting tablet that is taken once daily, normally in the morning, at approximately the same time each day.\nThe Tenex brand of guanfacine is used to treat high blood pressure (hypertension). It is sometimes given with other blood pressure medications.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nAvoid becoming overheated or dehydrated during excercise and in hot weather. Avoid drinking alcohol.\nTell your doctor if you regularly use other medicines that make you sleepy. They can add to sleepiness caused by Intuniv.\nBefore taking this medicine\nYou should not use Intuniv if you are allergic to guanfacine.\nIntuniv is not approved for use by anyone younger than 6 years old.\nTell your doctor if you have ever had:\nheart problems, coronary artery disease (clogged arteries);\na heart rhythm disorder;\na heart attack or stroke;\nhigh or low blood pressure;\nliver disease; or\nkidney disease.\nIt is not known whether Intuniv will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.\nHow should I take Intuniv?\nTake Intuniv exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nTake Intuniv with a full glass of water, milk, or other liquid.\nSwallow the Intuniv tablet whole and do not crush, chew, or break it.\nIf a child is using this medicine, tell your doctor if the child has any changes in weight. Guanfacine doses are based on weight in children, and any changes may affect your child\'s dose.\nYou should not stop using Intuniv suddenly. Stopping suddenly can raise your blood pressure and cause unpleasant symptoms.\nCall your doctor if you are sick with vomiting and cannot take your medicine as usual.\nYour dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes.\nYour doctor will need to check your progress on a regular basis. Your blood pressure and heart rate may also need to be checked.\nStore at room temperature away from moisture, heat, and light.\n','Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\nDrinking alcohol can increase certain side effects of Intuniv.\n'),(407,'invega','Take Invega exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nYou may take Invega with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nYour doctor will need to check your progress on a regular basis.\nStore at room temperature away from moisture, heat, and light.\n Detailed Invega dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness, fast heartbeats, and fainting.\n','Using Invega with other drugs that make you dizzy or lower your blood pressure can worsen these effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nSometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can interact with paliperidone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Invega drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Invega: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nStop taking Invega and call your doctor at once if you have any of these signs of a serious movement disorder:\ntremors or shaking in your arms or legs;\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or\nany new or unusual muscle movements you cannot control.\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nbreast swelling (in women or men), nipple discharge;\nchanges in menstrual periods;\nimpotence, penis erection that is painful or lasts 4 hours or longer;\nweight gain;\nlow white blood cell counts - fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing;\nhigh blood sugar - increased thirst, increased urination, hunger, fruity breath odor; or\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, fast or pounding heartbeats, fainting.\nCommon Invega side effects may include:\ndrowsiness;\nanxiety;\nmuscle stiffness, tremors or shaking;\nuncontrolled muscle movements, trouble with walking, balance, or speech;\nweight gain;\nupset stomach, constipation;\nfast heart rate; or\nstuffy nose, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Invega side effects (more detail)\n','Invega (paliperidone) is an antipsychotic medicine. It works by changing the effects of chemicals in the brain.\nInvega is used to treat schizophrenia in adults and teenagers who are at least 12 years old.\nInvega may also be used for purposes not listed in this medication guide.\n','Invega is not for use in psychotic conditions related to dementia. Paliperidone may cause heart failure, sudden death, or pneumonia in older adults with dementia-related psychosis.\nWhile you are taking Invega, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medicine.\nStop taking Invega and call your doctor at once if you have very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, or feeling like you might pass out.\nBefore taking this medicine\nYou should not use Invega if you are allergic to paliperidone or risperidone (Risperdal).\nPaliperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.\nHigh doses or long-term use of paliperidone can cause a serious movement disorder that may not be reversible. The longer you use Invega, the more likely you are to develop this disorder, especially if you are a woman or an older adult.\nTo make sure Invega is safe for you, tell your doctor if you have ever had:\nheart problems, or a heart attack;\nlong QT syndrome (in you or a family member);\nhigh or low blood pressure, or fainting spells;\nlow white blood cell (WBC) counts;\na serious neurologic disorder caused by taking an antipsychotic medicine;\nuncontrolled muscle movements in your face;\na stomach or intestinal disorder;\nliver or kidney disease;\nseizures or epilepsy;\nan electrolyte imbalance (such as low potassium or magnesium levels in your blood);\ndiabetes (paliperidone may raise your blood sugar); or\nbreast cancer.\nTell your doctor if you are pregnant or plan to become pregnant while using this medicine.\nTaking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. However, you may have withdrawal symptoms or other problems if you stop using your medicine during pregnancy. If you get pregnant, tell your doctor right away. Do not stop using Invega without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of paliperidone on the baby.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\n','While you are taking Invega, you may be more sensitive to heat. Avoid getting too hot, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking paliperidone.\nAvoid drinking alcohol. Dangerous side effects could occur.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy.\n'),(408,'invega-sustenna','Usual Adult Dose of Invega Sustenna for Schizophrenia:\n1-month extended-release injectable suspension:\n-For patients who have never taken oral paliperidone or oral or injectable risperidone, tolerability should be established with oral paliperidone or oral risperidone prior to initiating treatment with paliperidone extended-release injectable suspension.\n-Dosing in the US and Canada is the same; however, paliperidone extended-release injectable suspension is dosed as the salt (paliperidone palmitate) in the US and as the base (paliperidone) in Canada:\nPaliperidone palmitate:\n-Initial dose: 234 mg IM on day 1 followed by 156 mg IM one week later; administer IM into deltoid muscle\n-Maintenance dose: 117 mg IM monthly; administer into deltoid or gluteal muscle\n-Dose range: 39 to 234 mg based on patient tolerability and efficacy; dose adjustments may be made monthly, although full effect may not be evident for several months\n-Maximum dose: 234 mg/month\nPaliperidone (base):\n-Initial dose: 150 mg IM on day 1 followed by 100 mg IM one week later; administer IM into deltoid muscle\n-Maintenance dose: 75 mg IM monthly; administer into deltoid or gluteal muscle\n-Dose range: 25 to 150 mg based on patient tolerability and efficacy; dose adjustments may be made monthly, although full effect may not be evident for several months\nComments:\n-The dosing window for maintenance doses is 7 days before or after monthly time point.\n-If a dose is missed during initial titration or maintenance dosing, see dosage adjustment section for guidance.\nUsual Adult Dose od Invega Sustenna for Schizoaffective Disorder:\n1-month extended-release injectable suspension::\n-For patients who have never taken oral paliperidone or oral or injectable risperidone, tolerability should be established with oral paliperidone or oral risperidone prior to initiating treatment with paliperidone extended-release injectable suspension.\n-Dosing in the US and Canada is the same; however, paliperidone extended-release injectable suspension is dosed as the salt (paliperidone palmitate) in the US and as the base (paliperidone) in Canada:\nPaliperidone palmitate:\n-Initial dose: 234 mg IM on day 1 followed by 156 mg IM one week later; administer IM into deltoid muscle\n-Dose range: 78 to 234 mg based on patient tolerability and efficacy; dose adjustments may be made monthly, although full effect may not be evident for several months\n-Maximum dose: 234 mg/month\nPaliperidone (base):\n-Initial dose: 150 mg IM on day 1 followed by 100 mg IM one week later; administer IM into deltoid muscle\n-Dose range: 50 to 150 mg based on patient tolerability and efficacy; dose adjustments may be made monthly, although full effect may not be evident for several months\nComments:\n-The dosing window for maintenance doses is 7 days before or after monthly time point.\n-If a dose is missed during initial titration or maintenance dosing, see dosage adjustment section for guidance.\nUse: Treatment of schizoaffective disorder as monotherapy and as an adjunct to mood stabilizers and/or antidepressants\n Detailed Invega Sustenna dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Invega Sustenna.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include a headache with chest pain, fast or pounding heartbeats, and severe dizziness.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can affect Invega Sustenna. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Invega Sustenna drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Invega Sustenna: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nTell your doctor right away if you have any of these signs of a serious movement disorder:\ntremors or shaking in your arms or legs;\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or\nany new or unusual muscle movements you cannot control.\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\ntrouble swallowing;\na seizure (convulsions);\nbreast swelling (in women or men), nipple discharge;\nchanges in menstrual periods;\nimpotence, or penis erection that is painful or lasts 4 hours or longer;\nweight gain;\nfever, chills, sore throat, mouth sores, feeling light-headed;\nhigh blood sugar - increased thirst, increased urination, hunger, fruity breath odor; or\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, fast or pounding heartbeats, fainting.\nCommon Invega Sustenna side effects may include:\ndizziness, drowsiness;\ncold symptoms such as stuffy nose, sneezing, sore throat;\nfeeling restless or anxious;\nmuscle stiffness, tremors or shaking;\nuncontrolled muscle movements, trouble with walking, balance, or speech;\nabnormal movements of your eyes;\nweight gain;\nupset stomach, constipation;\nfast heart rate; or\npain or tenderness where the medicine was injected.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Invega Sustenna side effects (more detail)\n','Invega Sustenna (paliperidone) is an extended-release antipsychotic medicine given by injection.\nInvega Sustenna is prescription medicine used to treat schizophrenia in adults.\nInvega Sustenna is also used alone or with other medicines to treat schizoaffective disorder in adults.\n','Invega Sustenna is not approved for use in older adults with dementia-related psychosis.\nDizziness, sleepiness, and feeling less stable may happen with Invega Sustenna. This may lead to falling, which can cause broken bones or other health problems. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.\nSome people may get a severe muscle problem called tardive dyskinesia. This problem may lessen or go away after stopping Invega Sustenna, but it may not go away. The risk is greater with diabetes and in older adults, especially older women. The risk is greater with longer use or higher doses, but it may also occur after short-term use with low doses. Call your doctor right away if you have trouble controlling body movements or problems with your tongue, face, mouth, or jaw like tongue sticking out, puffing cheeks, mouth puckering, or chewing.\nLow white blood cell counts have happened with drugs like this one. This may lead to a higher chance of infection. Rarely, infections have been deadly. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat.\nBefore taking this medicine\nYou should not use Invega Sustenna if you are allergic to Invega Sustenna or to risperidone (Risperdal).\nInvega Sustenna may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.\nHigh doses or long-term use of paliperidone can cause a serious movement disorder that may not be reversible. The longer you use Invega Sustenna, the more likely you are to develop this disorder, especially if you are a woman or an older adult.\nBefore you receive your first injection, tell your doctor if you have never taken oral (by mouth) Invega Sustenna or risperidone.\nTo make sure Invega Sustenna is safe for you, tell your doctor if you have ever had:\nheart problems, or a heart attack;\nlong QT syndrome (in you or a family member);\nhigh or low blood pressure, or fainting spells;\nlow white blood cell (WBC) counts;\na serious neurologic disorder caused by taking an antipsychotic medicine;\nuncontrolled muscle movements in your face;\nliver or kidney disease;\nseizures or epilepsy;\nan electrolyte imbalance (such as low levels of potassium or magnesium in your blood);\ndiabetes (paliperidone may raise your blood sugar); or\nbreast cancer.\nTell your doctor if you are pregnant or plan to become pregnant while using Invega Sustenna.\nUsing antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. However, you may have withdrawal symptoms or other problems if you stop using your medicine during pregnancy. If you get pregnant, tell your doctor right away. Do not stop using Invega Sustenna without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of paliperidone on the baby.\nIt may not be safe to breastfeed while using Invega Sustenna. Ask your doctor about any risk.\nInvega Sustenna is not approved for use by anyone younger than 18 years old.\nHow is Invega Sustenna given?\nInvega Sustenna is injected into a muscle. A healthcare provider will give you this injection.\nInvega Sustenna is usually given only once per month, but the first two doses are given 1 week apart. Invega Trinza is usually given once every 3 months, after you have used Invega Sustenna for at least 4 months in a row.\nFollow your doctor\'s dosing instructions very carefully. Get your Invega Sustennas regularly to get the most benefit.\nYour doctor will need to check your progress while you are using Invega Sustenna.\n','Avoid drinking alcohol. Dangerous side effects could occur.\nWhile you are using Invega Sustenna, you may be more sensitive to very hot conditions. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise.\nAvoid driving or hazardous activity until you know how Invega Sustenna will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy.\n'),(409,'invokana','Usual Adult Dose for Diabetes Type 2:\nInitial dose: 100 mg orally once a day\n-May increase to 300 mg orally once a day for additional glycemic control but only in patients who have tolerated lower dose and who have an eGFR of 60 mL/min/1.73 m2 or greater\nMaximum dose: 300 mg/day\nComments:\n-Do not initiate in patients with an eGFR less than 45 mL/min/1.73 m2 as this drug will not be effective.\n-If used in combination with insulin or an insulin secretagogue, a lower dose of insulin or the insulin secretagogue should be considered to reduce the risk of hypoglycemia.\nUse: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.\n Detailed Invokana dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\ninsulin or other oral diabetes medicines;\na diuretic or \"water pill\";\ndigoxin, digitalis;\nrifampin;\nritonavir; or\nseizure medication - phenobarbital, phenytoin.\nThis list is not complete. Other drugs may interact with canagliflozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Invokana drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Invokana: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSeek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nlittle or no urination;\npain or burning when you urinate;\nnew pain, tenderness, sores, ulcers, or infections in your legs or feet;\nhigh potassium - nausea, irregular heartbeats, weakness, loss of movement;\nketoacidosis (too much acid in the blood) - nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing; or\ndehydration symptoms - dizziness, weakness, feeling light-headed (like you might pass out).\nYou may be more likely to have a broken bone while using Invokana. Talk with your doctor about how to avoid the risk of fractures.\nSide effects may be more likely to occur in older adults.\nCommon Invokana side effects may include:\ngenital infections; or\nurinating more than usual.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Invokana side effects (more detail)\n','Invokana (canagliflozin) is an oral diabetes medicine that helps control blood sugar levels. Canagliflozin works by helping the kidneys get rid of glucose from your bloodstream.\nInvokana is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.\nInvokana is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.\nInvokana is also used to reduce the risk of end-stage kidney disease and hospitalization or death from heart problems in adults who also have kidney problems caused by type 2 diabetes.\nInvokana is not for treating type 1 diabetes.\n','You should not use Invokana if you have severe kidney disease or if you are on dialysis.\nInvokana can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don\'t feel well.\nBefore taking this medicine\nYou should not use Invokana if you are allergic to canagliflozin, or if you have:\nsevere kidney disease (or if you are on dialysis).\nInvokana may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nheart problems;\na diabetic foot ulcer or amputation;\ncirculation problems or nerve problems in your legs or feet;\nkidney disease;\nliver disease;\nbladder infections or other urination problems;\na pancreas disorder;\nif you drink often, or drink large amounts of alcohol;\nif you are eating less than usual; or\nif you are on a low salt diet.\nFollow your doctor\'s instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.\nYou should not use canagliflozin during the second or third trimester of pregnancy.\nYou should not breast-feed while using this medicine.\nInvokana is not approved for use by anyone younger than 18 years old.\nHow should I take Invokana?\nInvokana is usually taken once per day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nInvokana is usually taken once per day, before the first meal of the day.\nYou may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Drink plenty of liquids while you are taking Invokana.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nInvokana is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using canagliflozin.\nStore at room temperature away from moisture and heat.\n','Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.\n'),(410,'irbesartan','Usual Adult Dose for Hypertension:\nInitial dose: 150 mg orally once a dayMaximum dose: 300 mg orally once a day\nUsual Adult Dose for Diabetic Nephropathy:\nTarget maintenance dose: 300 mg orally once a dayUse: Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (greater than 300 mg/day) in patients with type 2 diabetes and hypertension.\n Detailed Irbesartan dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Tell your doctor about all your other medicines, especially:\nheart or blood pressure medication;\nlithium; or\nNSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nThis list is not complete. Other drugs may affect irbesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Irbesartan drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nlittle or no urination;\nhigh potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.\nCommon side effects may include:\ndizziness;\nfeeling light-headed; or\nhigh potassium.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Irbesartan side effects (more detail)\n','Irbesartan is an angiotensin II receptor blocker (sometimes called an ARB).\nIrbesartan is used to treat high blood pressure (hypertension) in adults and children at least 6 years old. Lowering blood pressure may lower your risk of a stroke or heart attack.\nIrbesartan is also used to treat kidney problems caused by type 2 diabetes.\nIrbesartan may also be used for purposes not listed in this medication guide.\n','Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant.\nIf you have diabetes, do not take irbesartan with any medication that contains aliskiren (a blood pressure medicine).\nBefore taking this medicine\nYou should not use irbesartan if you are allergic to it.\nIf you have diabetes, do not take irbesartan with any medication that contains aliskiren (a blood pressure medicine).\nYou may also need to avoid taking irbesartan with aliskiren if you have kidney disease.\nTell your doctor if you have ever had:\na heart condition other than one being treated with irbesartan;\nkidney disease (or if you are on dialysis); or\nif you are on a low-salt diet.\nDo not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.\nIf you plan to get pregnant, ask your doctor for a safer medicine to use before and during pregnancy. Having high blood pressure during pregnancy may cause complications in the mother and the baby.\nYou should not breastfeed while using  irbesartan.\nHow should I take irbesartan?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nIrbesartan may be taken with or without food.\nYour blood pressure will need to be checked often. Your kidney function may also need to be checked.\nCall your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking irbesartan.\nIt may take up to 2 weeks before your blood pressure is under control. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms.\nYou may need to use blood pressure medicine for the rest of your life. Treatment may also include diet, exercise, lowering cholesterol, not smoking, and controlling diabetes.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include fast heartbeats or fainting.\n','Do not use potassium supplements or salt substitutes, unless your doctor has told you to.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy.\n'),(411,'iron-sucrose','General\nAlthough manufacturer makes no specific recommendations regarding test doses, test doses of iron sucrose (20–25 or 50 mg) have been administered in some patients.    (See Sensitivity Reactions under Cautions.)\nEnsure immediate availability of personnel trained to provide emergency treatment and appropriate agents for the treatment of a severe allergic or anaphylactic reaction when administering iron sucrose injection.\nAdministration\nIV Administration\nFor solution and drug compatibility information, see Compatibility under Stability.\nAdminister (diluted) by IV infusion or (undiluted) by slow IV injection.\nDo not mix with other drugs or add to parenteral nutrition solutions for IV infusion.\nDilution\nFor IV infusion, dilute in 0.9% sodium chloride injection; specific recommendations for dilution vary depending on the intended patient population (see Dosage). Do not dilute to concentrations <1 mg/mL.\nDosage\nDosage expressed in terms of mg of elemental iron. Iron sucrose injection contains the equivalent of 20 mg of elemental iron per mL.\nPediatric Patients\nIron Maintenance Treatment in Patients with Hemodialysis-dependent CKD\nIV\nChildren ≥2 years of age: 0.5 mg/kg (not to exceed 100 mg per dose) every 2 weeks for 12 weeks; may administer undiluted by slow IV injection over 5 minutes or diluted in 25 mL of 0.9% sodium chloride injection over 5–60 minutes.\nRepeat treatment if necessary.\nIron Maintenance Treatment in Patients with Non-dialysis-dependent CKD Receiving ESAs\nIV\nChildren ≥2 years of age: 0.5 mg/kg (not to exceed 100 mg per dose) every 4 weeks for 12 weeks; may administer undiluted by slow IV injection over 5 minutes or diluted in 25 mL of 0.9% sodium chloride injection over 5–60 minutes.\nRepeat treatment if necessary.\nIron Maintenance Treatment in Patients with Peritoneal Dialysis-dependent CKD Receiving ESAs\nIV\nChildren ≥2 years of age: 0.5 mg/kg (not to exceed 100 mg per dose) every 4 weeks for 12 weeks; may administer undiluted by slow IV injection over 5 minutes or diluted in 25 mL of 0.9% sodium chloride injection over 5–60 minutes.\nRepeat treatment if necessary.\nAdults\nPatients with Hemodialysis-dependent CKD\nIV\n100 mg by slow IV injection (over 2–5 minutes) or by IV infusion (diluted in a maximum of 100 mL of 0.9% sodium chloride injection and administered over at least 15 minutes) during each consecutive hemodialysis session. Administer early during dialysis procedure.\nA cumulative dose of 1 g of iron sucrose usually is required.\nRepeat treatment if necessary.\nPatients with Non-dialysis-dependent CKD\nIV\n200 mg by slow IV injection (over 2–5 minutes) or IV infusion (diluted in a maximum of 100 mL of 0.9% sodium chloride injection and administered over 15 minutes) for a total of 5 doses; administer the doses on 5 different occasions over a 14-day period.\nAlso has been administered in a dosage of 500 mg by IV infusion (diluted in a maximum of 250 mL of 0.9% sodium chloride injection) on days 1 and 14; administer each dose over 3.5–4 hours.\nRepeat treatment if necessary.\nPatients with Peritoneal Dialysis-dependent CKD\nIV\nAdminister a series of 3 doses, each dose spaced 14 days apart, over 28 days. For the first 2 doses, administer 300 mg by IV infusion (diluted in a maximum of 250 mL of 0.9% sodium chloride injection and administered over 1.5 hours); follow with a dose of 400 mg (diluted in a maximum of 250 mL of 0.9% sodium chloride injection and administered over 2.5 hours).\nRepeat treatment if necessary.\nPrescribing Limits\nPediatric Patients\nIV\nDo not exceed 100 mg per dose.\nSpecial Populations\nGeriatric Patients\nSelect dosage with caution because of age-related decreases in hepatic, renal, and/or cardiac function and of concomitant disease and/or other drug therapies.\n Detailed Iron sucrose dosage information\n','Oral Iron Preparations\nNo formal drug interaction studies to date.\nLike other parenteral iron preparations, iron sucrose injection may be expected to reduce absorption of concomitantly administered oral iron.\n Iron sucrose drug interactions (more detail)\n',NULL,'Iron Deficiency Anemia in Patients with Chronic Kidney Disease\nTreatment of iron deficiency anemia in patients with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis.        \nIn patients with CKD on hemodialysis, IV iron superior to orally administered iron in increasing hemoglobin concentrations and/or minimizing dosage of an erythropoiesis-stimulating agent (ESA); the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) guidelines state that the IV route of iron administration is preferred in such patients.\nAvailable data suggest that iron sucrose and sodium ferric gluconate may be associated less frequently with serious adverse effects (e.g., hypersensitivity reactions) than iron dextran.   \nIron sucrose injection also used as iron maintenance therapy in children with dialysis-dependent (hemodialysis or peritoneal dialysis) or non-dialysis-dependent CKD. (See Pediatric Use under Cautions.)\n',NULL,NULL),(412,'isoniazid','Follow all directions on your prescription label. Do not take  isoniazid in larger or smaller amounts or for longer than recommended.\nTake isoniazid on an empty stomach, at least 1 hour before or 2 hours after a meal.\nUse this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Isoniazid will not treat a viral infection such as the flu or a common cold.\nYour liver function may need to be checked every month while you are taking this medicine.\nYour doctor may have you take extra vitamin B6 while you are taking isoniazid. Take only the amount of vitamin B6 that your doctor has prescribed.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Isoniazid dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include vomiting, severe dizziness or drowsiness, slurred speech, blurred vision, hallucinations, trouble breathing, increased thirst, increased urination, fruity breath odor, or loss of consciousness.\n','Many drugs can interact with isoniazid. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with isoniazid. Give a list of all your medicines to any healthcare provider who treats you.\n Isoniazid drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nSeek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using isoniazid.\nCall your doctor at once if you have:\nsudden weakness or ill feeling, or fever for 3 days or longer;\npain in your upper stomach (may spread to your back), nausea, loss of appetite;\ndark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nvision changes, pain behind your eyes;\nconfusion, memory problems, unusual thoughts or behavior;\na seizure (convulsions); or\npale skin, easy bruising or bleeding (nosebleeds, bleeding gums).\nCommon side effects may include:\nnumbness, tingling, or burning pain in your hands or feet;\nnausea, vomiting, upset stomach; or\nabnormal liver function tests.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Isoniazid side effects (more detail)\n','Isoniazid is an antibiotic that fights bacteria.\nIsoniazid is used to treat and to prevent tuberculosis (TB). You may need to take other TB medicines in combination with isoniazid.\nWhen treating active TB, isoniazid must be used with other TB medicines. Tuberculosis can become resistant to treatment if isoniazid is used alone. Take all your medicines as prescribed by your doctor.\nIsoniazid may also be used for purposes not listed in this medication guide.\n','You should not use  isoniazid if you have active liver disease, or if you have taken isoniazid in the past and it caused liver problems, fever, chills, joint pain, or severe allergic reaction.\nSerious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medicine, especially if you are between the ages of 35 and 65. Your liver function may need to be checked every month while you are taking this medicine.\nCall your doctor right away if you have: nausea, upper stomach pain, loss of appetite, and feeling weak or tired.\nAvoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid.\nBefore taking this medicine\nYou should not use isoniazid if you are allergic to it, or if you have:\nactive liver disease;\na history of severe allergic reaction to isoniazid;\na history of hepatitis or other liver problems caused by taking isoniazid; or\na history of severe isoniazid side effects such as fever, chills, or joint pain and swelling.\nTo make sure isoniazid is safe for you, tell your doctor if you have:\na history of liver disease;\nkidney disease;\nnerve problems that cause pain, weakness, or numbness;\ndiabetes;\nHIV or AIDS;\nif you drink alcohol daily;\nif you are malnourished;\nif you use any drugs that are injected; or\nif you have ever had to stop taking isoniazid for any reason.\nIf you are 35 years or older, your doctor will check your liver enzymes before you start treatment, to make sure you can safely use isoniazid.\nSerious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medication, even months after stopping. The risk of liver problems is highest in adults between the ages of 35 and 65.\nSerious liver problems may be more likely to occur in women, especially after childbirth, or in women of Hispanic or African-American ancestry. Ask your doctor about your specific risk.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nTalk to your doctor if you will be breast-feeding a baby during your treatment with isoniazid. This medicine can pass into breast milk, but it will not treat or prevent tuberculosis in the nursing infant.\n','Avoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid.\nYou may need to avoid certain foods while you are taking isoniazid. This includes red wine, aged cheese, dried meats, and tuna or other types of fish.\n'),(413,'isosorbide-dinitrate','Before using isosorbide dinitrate to treat a sudden angina attack, your doctor may want you to first use a nitroglycerin sublingual tablet. Follow your doctor\'s instructions about what medications to use during an attack and how much time to allow between doses.\nFollow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. If you use too much isosorbide dinitrate, it might stop working as well in controlling your condition.\nTry to rest or stay seated when you take this medicine (may cause dizziness or fainting).\nTo prevent angina attacks, isosorbide dinitrate is usually taken at regular intervals.\nTo treat an angina attack that has already begun, use the medicine at the first sign of chest pain. Place the tablet under your tongue and allow it to dissolve slowly. Do not chew or swallow it.\nYou may use the sublingual tablet within 15 minutes before an activity you think might cause chest pain. Follow your doctor\'s instructions.\nDo not crush, chew, break, or open an extended-release capsule or tablet. Swallow it whole.\nFollow your doctor\'s dosing instructions very carefully. If your doctor changes your brand, strength, or type of isosorbide dinitrate, your dosage needs may change. Ask your pharmacist if you have any questions about the new kind of isosorbide dinitrate you receive at the pharmacy.\nSeek emergency medical attention if your chest pain gets worse or lasts longer than 5 minutes, especially if you have trouble breathing or feel weak, dizzy, or nauseated, or lightheaded.\nYou may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Prolonged illness can lead to a serious electrolyte imbalance, making it dangerous for you to use isosorbide dinitrate.\nIf you take isosorbide dinitrate on a regular schedule to prevent angina, do not stop taking it suddenly or you could have a severe attack of angina. Keep this medicine on hand at all times. Get your prescription refilled before you run out of medicine completely.\nStore at room temperature, away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Isosorbide dinitrate dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nSince isosorbide dinitrate is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 2 hours away.\nIf you are using the extended-release capsule or tablet and your next dose is less than 6 hours away, skip the missed dose and use the medicine at your next regularly scheduled time.\nDo not use extra medicine to make up a missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention if you think you have used too much of  isosorbide dinitrate. An overdose of isosorbide dinitrate can be fatal.\nOverdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions).\n','Taking isosorbide dinitrate with certain other medicines can cause severely low blood pressure. This includes medicine to treat erectile dysfunction or pulmonary arterial hypertension. Serious, life-threatening side effects may occur.\nTell your doctor about all your current medicines and any you start or stop using, especially:\navanafil (Stendra);\na diuretic or \"water pill\";\nnitroglycerin;\nriociguat (Adempas);\nsildenafil (Viagra, Revatio);\ntadalafil (Cialis, Adcirca); or\nvardenafil (Levitra, Staxyn).\nThis list is not complete. Other drugs may interact with isosorbide dinitrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Isosorbide dinitrate drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nworsening angina pain;\nfast or slow heart rate; or\npounding heartbeats or fluttering in your chest.\nIsosorbide dinitrate can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin. Do not stop taking  isosorbide dinitrate to avoid headaches. Ask your doctor before using any headache pain medication.\nCommon side effects may be more likely to occur, such as:\nheadache; or\nflushing (warmth, redness, or tingly feeling).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Isosorbide dinitrate side effects (more detail)\n','Isosorbide dinitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.\nIsosorbide dinitrate is used to treat or prevent attacks of chest pain (angina).\nOnly the sublingual tablet should be used to treat an angina attack that has already begun.\nIsosorbide dinitrate regular and extended-release tablets are used to prevent angina attacks but will not treat an angina attack.\nIsosorbide dinitrate may also be used for purposes not listed in this medication guide.\n','You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide dinitrate. Taking these medicine together can cause a sudden and serious decrease in blood pressure.\nSeek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, sweating, general ill feeling).\nBefore taking this medicine\nYou should not use isosorbide dinitrate if:\nyou are allergic to isosorbide dinitrate, isosorbide mononitrate, or nitroglycerin; or\nyou have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating).\nYou should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide dinitrate. Taking these medicines together can cause a sudden and serious decrease in blood pressure.\nTo make sure isosorbide dinitrate is safe for you, tell your doctor if you have:\ncongestive heart failure;\nkidney disease; or\nlow blood pressure.\nIt is not known whether  isosorbide dinitrate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether isosorbide dinitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.\n','This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\nAvoid drinking alcohol. Alcohol may increase certain side effects of isosorbide dinitrate (dizziness, drowsiness, feeling light-headed, or fainting).\n'),(414,'isosorbide-mononitrate','Take isosorbide mononitrate exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.\nThis form of nitrate is used to reduce the number of angina attacks over a long time. It will not relieve an attack that has already started because it works too slowly. The extended-release form gradually releases medicine to provide its effect for 8 to 10 hours. Check with your doctor if you also need a fast-acting medicine to relieve the pain of an angina attack.\nYou should take isosorbide mononitrate first thing in the morning and follow the same schedule each day. Isosorbide mononitrate works best if you have a \"drug-free\" period of time every day when you do not take it. Your doctor will schedule your doses during the day to allow for a drug-free time. Follow the schedule of dosing carefully so the medicine will work properly.\nSwallow the extended-release tablet whole with a half glass of water. Do not split, crush, or chew it.\nDosing\nThe dose of isosorbide mononitrate will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of isosorbide mononitrate. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor prevention of angina:\nFor oral dosage form (extended-release tablets):\nAdults—At first, 30 or 60 milligrams (mg) once a day. Take the dose in the morning right after you wake up. Your doctor may increase your dose as needed.\nChildren—Use and dose must be determined by your doctor.\nFor oral dosage form (tablets):\nAdults—20 milligrams (mg) two times a day. Take the first dose in the morning right after you wake up, and the second dose 7 hours later.\nChildren—Use and dose must be determined by your doctor.\nMissed dose\nIf you miss a dose of isosorbide mononitrate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Isosorbide mononitrate dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nLess common\nAbnormal heart sound\nabsence of or decrease in body movement\narm, back, or jaw pain\nblack, tarry stools\nbladder pain\nbleeding after defecation\nbleeding gums\nblood in the urine or stools\nblurred vision\nbody aches or pain\nburning while urinating\nburning, crawling, itching, numbness, prickling, \"pins and needles\", or tingling feelings\nchest pain or discomfort\nchest tightness or heaviness\nchills\ncold sweats\ncolds\nconfusion\nconvulsions\ncough or hoarseness\ndecreased urine\ndiarrhea\ndifficult or labored breathing\ndifficult, burning, or painful urination\ndilated neck veins\ndizziness\ndizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position\ndry mouth\near congestion\nextra heartbeats\nfainting\nfast, slow, irregular, pounding, or racing heartbeat or pulse\nfever or chills\nflu-like symptoms\nfrequent urge to urinate\nfrequent urination\ngeneral feeling of discomfort or illness\nheadache\nheadache, severe and throbbing\nheart murmur\nincreased need to urinate\nincreased sweating\nincreased thirst\nincreased volume of pale, dilute urine\nirregular breathing\nitching, pain, redness, or swelling on the leg\njoint pain, stiffness, or swelling\nlightheadedness\nloss of appetite\nloss of voice\nlower back, side, or stomach pain\nmuscle aches and pains\nmuscle cramps\nnasal congestion\nnausea or vomiting\nnervousness\nnumbness or tingling in the hands, feet, or lips\npain or discomfort in the arms, jaw, back, or neck\npain, tension, and weakness upon walking that subsides during periods of rest\npartial or slight paralysis\npassing urine more often\npinpoint red or purple spots on the skin\npounding in the ears\nrunny nose\nshakiness in the legs, arms, hands, or feet\nshivering\nsneezing\nsore on the leg\nsore throat\nsudden decrease in the amount of urine\nsweating\nswelling\nswelling of the face, fingers, feet, or lower legs\ntightness in the chest\ntrembling or shaking of the hands or feet\ntrouble sleeping\ntroubled breathing\nuncomfortable swelling around the anus\nunusual bleeding or bruising\nunusual tiredness or weakness\nvomiting of blood or material that looks like coffee grounds\nweakness\nweight gain\nRare\nBluish-colored lips, fingernails, or palms\ndark urine\npale skin\nrapid heart rate\nGet emergency help immediately if any of the following symptoms of overdose occur:\nSymptoms of overdose\nBlurred or loss of vision\nbulging soft spot on the head of an infant\nchange in consciousness\nchange in the ability to see colors, especially blue or yellow\ncold, clammy skin\ndisturbed color perception\ndouble vision\nfeeling of constant movement of self or surroundings\nhalos around lights\nheadache, severe and throbbing\nloss of consciousness\nnight blindness\noverbright appearance of lights\nparalysis\nsensation of spinning\ntunnel vision\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nLess common\nAcid or sour stomach\nanxiety\nback pain\nbelching\nblemishes on the skin\nbloated\nbreast pain\nburning feeling in the chest or stomach\nburning, dry, or itching eyes\nchange in color vision\nchanges in vision\ncold sweats\ncongestion\nconstipation\ncontinuing ringing or buzzing or other unexplained noise in the ears\ncough producing mucus\ndecreased interest in sexual intercourse\ndifficulty seeing at night\ndifficulty with moving\ndischarge, excessive tearing\ndouble vision\ndrooping upper eyelids\ndull ache or feeling of pressure or heaviness in the legs\nearache\nexcess air or gas in the stomach or intestines\nfeeling of constant movement of self or surroundings\nfeeling of warmth\nfeeling unusually cold\nfrequent urge to defecate\nfrozen shoulder\nfull feeling\nhearing loss\nheartburn\nhyperventilation\ninability to have or keep an erection\nincreased appetite\nincreased sensitivity of the eyes to sunlight\nincreased sputum\nindigestion\nirritability\nitching skin near damaged veins\nlack or loss of strength\nloss in sexual ability, desire, drive, or performance\nmuscle or bone pain\nmuscle stiffness or weakness\nnightmares\nnoisy breathing\npain or tenderness around the eyes and cheekbones\npassing gas\npimples\npoor concentration\nrash\nredness of the face, neck, arms, and occasionally, upper chest\nredness, pain, swelling of the eye, eyelid, or inner lining of the eyelid\nredness, swelling, or soreness of the tongue\nrestlessness\nseeing double\nsensation of spinning\nsleepiness or unusual drowsiness\nsmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope\nsmall lumps under the skin\nsore mouth or tongue\nstiff neck\nstomach bloating, burning, cramping, or pain\nstomach discomfort or upset\nstraining while passing stool\nstuffy nose\nsudden sweating\nswollen feet and ankles\ntender, swollen glands in the neck\ntenderness in the stomach area\nterrifying dreams causing sleep disturbances\ntooth disorder\ntrouble swallowing\nuncontrolled twisting movements of the neck\nvoice changes\nweight loss\nwhite patches in the mouth, tongue, or throat\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Isosorbide mononitrate side effects (more detail)\n','Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). It does not work fast enough to relieve the pain of an angina attack that has already started.\nIsosorbide mononitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.\nIsosorbide mononitrate is available only with your doctor\'s prescription.\n','If you will be taking isosorbide mononitrate for a long time, it is very important that your doctor check your progress at regular visits to make sure that isosorbide mononitrate is working properly. Blood tests may be needed to check for unwanted effects.\nDo not take riociguat (Adempas®), sildenafil (Viagra®), tadalafil (Cialis®), or vardenafil (Levitra®) while you are using isosorbide mononitrate. Using these medicines together may lower your blood pressure and cause blurred vision, dizziness, lightheadedness, or fainting. If you are taking these medicines and you experience an angina attack, you must go to the hospital right away.\nIsosorbide mononitrate may cause headaches. These headaches are a sign that the medicine is working. Do not stop using the medicine or change the time you use it in order to avoid the headaches. If you have severe pain, talk with your doctor.\nDizziness, lightheadedness, or faintness may occur, especially when you get up quickly from a lying or sitting position. Getting up slowly may help.\nDizziness, lightheadedness, or fainting is also more likely to occur if you drink alcohol, stand for long periods of time, exercise, or if the weather is hot. While you are taking isosorbide mononitrate, be careful to limit the amount of alcohol you drink. Also, use extra care during exercise or hot weather or if you must stand for long periods of time.\nDo not stop using isosorbide mononitrate without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely.\nMake sure any doctor or dentist who treats you knows that you are using isosorbide mononitrate. You may need to stop using isosorbide mononitrate several days before you have medical tests.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.\n',NULL),(415,'isosorbide_mononitrate','Take isosorbide mononitrate exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. If you use too much isosorbide mononitrate, it might stop working as well in controlling your condition.\nTry to rest or stay seated when you take this medicine (may cause dizziness or fainting).\nDo not crush, chew, or break an extended-release tablet. Swallow it whole.\nNot all brands and forms of isosorbide mononitrate are taken the same number of times per day. You may need to take the medicine only once daily, in the morning after getting out of bed. You may also need a second dose later in the day.\nFollow your doctor\'s dosing instructions very carefully. If your doctor changes your brand, strength, or type of isosorbide mononitrate, your dosage needs may change. Ask your pharmacist if you have any questions about the new brand of medicine you receive at the pharmacy.\nUse this medicine regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely.\nYou should not stop using isosorbide mononitrate suddenly or you could have a severe attack of angina. Keep this medicine on hand at all times. Get your prescription refilled before you run out of medicine completely.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Isosorbide mononitrate dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of isosorbide mononitrate can be fatal.\nOverdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions).\n','Taking isosorbide mononitrate with certain other medicines can cause severely low blood pressure. This includes medicine to treat erectile dysfunction or pulmonary arterial hypertension. Serious, life-threatening side effects may occur.\nTell your doctor about all your current medicines and any you start or stop using, especially:\nerectile dysfunction medication (including Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil, others);\na diuretic or \"water pill\";\nblood pressure medications including calcium channel blockers (such as nifedipine, Procardia);\nnitroglycerin; or\nriociguat (Adempas);\nThis list is not complete. Other drugs may interact with isosorbide mononitrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Isosorbide mononitrate drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to isosorbide mononitrate: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nworsening angina pain;\nfast or slow heart rate; or\npounding heartbeats or fluttering in your chest.\nIsosorbide mononitrate can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin. Do not stop taking this medicine to avoid headaches. Ask your doctor before using any headache pain medication.\nCommon isosorbide mononitrate side effects may include:\nheadache;\ndizziness upon standing; or\nflushing (warmth, redness, or tingly feeling).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Isosorbide mononitrate side effects (more detail)\n','Isosorbide mononitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.\nIsosorbide mononitrate is used to prevent angina attacks (chest pain).\nIsosorbide mononitrate will not treat an angina attack that has already begun.\n','You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide mononitrate. Taking these medicines together can cause a sudden and serious decrease in blood pressure.\nSeek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, sweating, general ill feeling).\nDo not stop taking this medicine suddenly. Stopping suddenly could cause a severe angina attack.\nIsosorbide mononitrate can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use the medication. Do not stop taking isosorbide mononitrate. Ask your doctor before using any headache pain medication.\nUse this medicine regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely.\nBefore taking this medicine\nYou should not use isosorbide mononitrate if:\nyou are allergic to isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin; or\nyou have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating).\nYou should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide mononitrate. Taking these medicines together can cause a sudden and serious decrease in blood pressure.\nTo make sure this medicine is safe for you, tell your doctor if you have:\ncongestive heart failure;\nkidney disease; or\nlow blood pressure.\nIt is not known whether this medicine will harm an unborn baby, although animal studies have not shown harm. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether isosorbide mononitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.\n','This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\nAvoid drinking alcohol. Alcohol may increase certain side effects of isosorbide mononitrate (dizziness, drowsiness, feeling light-headed, or fainting).\n'),(416,'isotretinoin','Usual Adult Dose for Acne:\nMaintenance dose: 0.25 to 0.5 mg/kg orally 2 times a dayMaximum dose: Up to 2 mg/kg/dayDuration of therapy: Up to 20 weeksComments:-Patients should take some formulations of this drug with food.-Prior to increasing the dose, patients should be asked about their compliance with treatment (e.g., taking this drug with food).-Patients with very severe acne, scarring, or primary manifestations on the trunk may require 2 mg/kg/day dosing.-Any patient requesting refills requires a new prescription and a new authorization from the iPLEDGE program.-The safety and efficacy of once a day dosing has not been established; thus, once a day dosing is not recommended.Use: Treatment of severe recalcitrant nodular acne in patients who are unresponsive to conventional therapy, including systemic antibiotics\nUsual Pediatric Dose for Acne:\n12 years or older:-Maintenance dose: 0.25 to 0.5 mg/kg orally 2 times a day-Maximum dose: 2 mg/kg/day-Duration of therapy: Up to 20 weeksComments:-Patients should take some formulations of this drug with food.-Prior to increasing the dose, patients should be asked about their compliance with treatment (e.g., taking this drug with food).-Patients with very severe acne, scarring, or primary manifestations on the trunk may require 2 mg/kg/day dosing.-Any patient requesting refills requires a new prescription and a new authorization from the iPLEDGE program.-The safety and efficacy of once a day dosing has not been established; thus, once a day dosing is not recommended.Use: Treatment of severe recalcitrant nodular acne in patients who are unresponsive to conventional therapy, including systemic antibiotics\n Detailed Isotretinoin dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Tell your doctor about all your other medicines, especially:\nphenytoin;\nSt. John\'s wort;\nvitamin or mineral supplements;\nprogestin-only birth control pills (mini-pills);\nsteroid medicine; or\na tetracycline antibiotic, including doxycycline or minocycline.\nThis list is not complete. Other drugs may affect isotretinoin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Isotretinoin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nStop using isotretinoin and call your doctor at once if you have:\nproblems with your vision or hearing;\nmuscle or joint pain, bone pain, back pain;\nincreased thirst, increased urination;\nhallucinations, (see or hearing things that are not real);\nsymptoms of depression--unusual mood changes, crying spells, feelings of low self-worth, loss of interest in things you once enjoyed, new sleep problems, thoughts about hurting yourself;\nsigns of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes);\nsevere stomach problems--severe stomach or chest pain, pain when swallowing, heartburn, diarrhea, rectal bleeding, bloody or tarry stools; or\nincreased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.\nCommon side effects may include:\ndryness of your skin, lips, eyes, or nose (you may have nosebleeds);\nvision problems;\nheadache, back pain, joint pain, muscle problems;\nskin reactions; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Isotretinoin side effects (more detail)\n','Isotretinoin is a form of vitamin A that is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.\nIsotretinoin is available only from a certified pharmacy under a special program called iPLEDGE.\nIsotretinoin may also be used for purposes not listed in this medication guide.\n','Isotretinoin in just a single dose can cause severe birth defects or death of a baby. Never use  isotretinoin if you are pregnant or may become pregnant.\nYou must have a negative pregnancy test before taking isotretinoin. You will also be required to use two forms of birth control to prevent pregnancy while taking this medicine. Stop using isotretinoin and call your doctor at once if you think you might be pregnant.\nBefore taking this medicine\nIsotretinoin can cause miscarriage, premature birth, severe birth defects, or death of a baby if the mother takes this medicine at the time of conception or during pregnancy. Even one dose of isotretinoin can cause major birth defects of the baby\'s ears, eyes, face, skull, heart, and brain. Never use isotretinoin if you are pregnant.\nFor Women: Unless you have had your uterus and ovaries removed (total hysterectomy with oophorectomy) or have been in menopause for at least 12 months in a row, you are considered to be of child-bearing potential. You must have a negative pregnancy test before you start taking isotretinoin, before each prescription is refilled, right after you take your last dose of isotretinoin, and again 30 days later. All pregnancy testing is required by the iPLEDGE program.\nYou must agree in writing to use two specific forms of birth control beginning 30 days before you start taking isotretinoin and ending 30 days after your last dose. Both a primary and a secondary form of birth control must be used together.\nPrimary forms of birth control include:\ntubal ligation (tubes tied);\nvasectomy of the male sexual partner;\nan IUD (intrauterine device);\nestrogen-containing birth control pills (not mini-pills); and\nhormonal birth control patches, implants, injections, or vaginal ring.\nSecondary forms of birth control include:\na male latex condom with or without spermicide;\na diaphragm plus a spermicide;\na cervical cap plus a spermicide; and\na vaginal sponge containing a spermicide.\nStop using isotretinoin and call your doctor at once if you have unprotected sex, if you quit using birth control, if your period is late, or if you think you might be pregnant. If you get pregnant while taking isotretinoin, call the iPLEDGE pregnancy registry at 1-866-495-0654.\nNot having sexual intercourse (abstinence) is the most effective method of preventing pregnancy.\nYou should not use isotretinoin if you are allergic to it.\nTell your doctor if you have ever had:\ndepression or mental illness;\nasthma;\nliver disease;\ndiabetes;\nheart disease or high cholesterol;\nosteoporosis or low bone mineral density;\nan eating disorder such as anorexia;\na food or drug allergy; or\nan intestinal disorder such as inflammatory bowel disease or ulcerative colitis.\nYou should not breastfeed while using this medicine.\nIsotretinoin is not approved for use by anyone younger than 12 years old.\nHow should I take isotretinoin?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nEach prescription of isotretinoin must be filled within 7 days of the date it was written by your doctor. You will receive no more than a 30-day supply of isotretinoin at one time.\nAlways take isotretinoin with a full glass of water. Do not chew or suck on the capsule. Swallow it whole.\nFollow all directions about taking isotretinoin with or without food.\nUse  isotretinoin for the full prescribed length of time. Your acne may seem to get worse at first, but should then begin to improve.\nYou may need frequent blood tests.\nNever share this medicine with another person, even if they have the same symptoms you have.\nStore at room temperature away from moisture, heat, and light.\nWhat happens if I miss a dose?\nSkip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include headache, dizziness, vomiting, stomach pain, warmth or tingling in your face, swollen or cracked lips, and loss of balance or coordination.\n','Do not take a vitamin or mineral supplement that contains vitamin A.\nDo not donate blood while taking isotretinoin and for at least 30 days after you stop taking it. Donated blood that is later given to a pregnant woman could lead to birth defects in her baby if the blood contains any level of isotretinoin.\nWhile you are taking isotretinoin and for at least 6 months after your last dose: Do not use wax hair removers or have dermabrasion or laser skin treatments. Scarring may result.\nIsotretinoin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.\nAvoid driving or hazardous activity until you know how  isotretinoin will affect you. Isotretinoin may impair your vision, especially at night.\n'),(417,'itraconazole','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nDo not share  itraconazole with another person, even if they have the same symptoms you have.\nThe itraconazole capsule should be taken with food.\nSwallow the capsule whole and do not crush, chew, break, or open it.\nTake itraconazole oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal. Swish the liquid in your mouth for several seconds before swallowing it.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nThe Sporanox PulsePak has a special dosing schedule that includes not taking the medicine for several days in a row. Follow all dosing instructions carefully.\nItraconazole capsules should not be used in place of itraconazole oral solution (liquid) if that is what your doctor has prescribed. Avoid medication errors by using only the form and strength your doctor prescribes.\nIf you also take a stomach acid reducer (Tagamet, Pepcid, Axid, Zantac, and others), take itraconazole with an acidic drink such as non-diet cola.\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Itraconazole will not treat a viral infection such as the flu or a common cold.\nYou may need frequent medical tests.\nStore at room temperature away from moisture, heat, and light.\n Detailed Itraconazole dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can affect itraconazole, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Itraconazole drug interactions (more detail)\nDoes Itraconazole interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives, severe skin rash, tingling in your arms or legs; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using itraconazole and call your doctor at once if you have signs of congestive heart failure: feeling tired or short of breath, cough with mucus, fast heartbeats, swelling, rapid weight gain, or sleep problems.\nKeep taking itraconazole but call your doctor at once if you have:\nconfusion, a light-headed feeling (like you might pass out);\nblurred vision, double vision, ringing in your ears, problems with hearing;\nfast heartbeats;\nnumbness or tingly feeling, loss of bladder control;\nlittle or no urinating, pain or burning when you urinate;\nlow potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, muscle weakness or limp feeling;\npancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting; or\nliver problems--nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nheadache, dizziness, drowsiness, tiredness;\nincreased blood pressure;\nrash, itching;\nnausea, vomiting, stomach pain, diarrhea, constipation;\nswelling;\nabnormal liver function or blood tests;\nfever, muscle or joint pain;\nunusual or unpleasant taste in your mouth;\nhair loss;\nimpotence, erection problems; or\nchanges in your menstrual periods.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Itraconazole side effects (more detail)\n','Itraconazole is an antifungal medication that is used in adults to treat infections caused by fungus. This includes infections in any part of the body including the lungs, mouth or throat, toenails, or fingernails.\nSome brands of itraconazole are not for use in treating fungal infections of the fingernails or toenails. Avoid medication errors by using only the brand and strength your doctor prescribes.\nItraconazole may also be used for purposes not listed in this medication guide.\n','You should not take  itraconazole if you have ever had heart failure.\nIf you have liver or kidney disease, you should not take itraconazole with colchicine, fesoterodine, or solifenacin.\nItraconazole may harm an unborn baby. Avoid getting pregnant while taking itraconazole and for 2 months after your last dose.\nStop using itraconazole and call your doctor at once if you have signs of congestive heart failure: feeling tired or short of breath, cough with mucus, fast heartbeats, swelling, rapid weight gain, or sleep problems.\nLife-threatening side effects may occur if you take itraconazole with certain other drugs. Tell your doctor about all your current medicines and any you start or stop using.\nBefore taking this medicine\nYou should not take this medicine if you are allergic to itraconazole or similar medicines such as fluconazole or ketoconazole, or if you have ever had congestive heart failure.\nLife-threatening side effects may occur if you take itraconazole with certain other drugs. Your doctor may change your treatment plan if you have used other medicines in the past 2 weeks, especially:\navanafil;\ncisapride;\neliglustat;\nirinotecan;\nisavuconazonium;\nmethadone;\nnaloxegol;\nranolazine;\nticagrelor;\nlurasidone or pimozide (anti-psychotic medications);\nlomitapide, lovastatin, simvastatin (cholesterol-lowering medicines);\ndihydroergotamine, ergonovine, ergotamine, or methylergonovine (ergot medicines);\neplerenone, felodipine, ivabradine, or nisoldipine (heart or blood pressure medicines);\ndisopyramide, dofetilide, dronedarone, or quinidine (medicines for heart rhythm disorders); or\noral midazolam, or triazolam (Valium-like sedatives).\nIf you have liver or kidney disease, you should not take itraconazole with colchicine, fesoterodine, solifenacin, or telithromycin.\nItraconazole may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 months after your last dose. Tell your doctor if you become pregnant.\nTell your doctor if you have ever had:\nheart problems;\ncystic fibrosis or other lung problems;\nliver or kidney disease; or\na weak immune system.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\n','Avoid driving or hazardous activity until you know how  itraconazole will affect you. Your reactions could be impaired.\nAvoid taking antacids within 1 hour before or 2 hours after you take itraconazole. Some antacids can make it harder for your body to absorb itraconazole.\n'),(418,'ivabradine','Usual Adult Dose for Congestive Heart Failure:\nInitial dose: 5 mg orally twice a day with mealsMaximum dose: 7.5 mg orally twice a dayComments:-In patients with a history of conduction defects or in patients whom bradycardia could lead to hemodynamic compromise, start with 2.5 mg orally twice a day.-Assess after 2 weeks and adjust dose to maintain tolerability and achieve resting heart rate between 50 and 60 beats per minute (bpm); if resting heart rate is greater than 60 bpm, increase by 2.5 mg twice daily to a maximum of 7.5 mg twice daily; if resting heart rate is less than 50 bpm or bradycardia signs and symptoms occur, decrease by 2.5 mg twice daily (discontinue if current dose is 2.5 mg orally twice a day).Use: To reduce worsening heart failure hospitalization risk in patients with stable, symptomatic chronic heart failure and left ventricular ejection fraction (LVEF) at or below 35%, who are in sinus rhythm with resting heart rate at or above 70 bpm and are either unable to tolerate or have a contraindication to beta-blockers.\nUsual Pediatric Dose for Congestive Heart Failure:\n6 Months or Older:Less than 40 kg (oral solution):-Initial dose: 0.05 mg/kg orally twice a day with food; assess patient at 2-week intervals and adjust dose by 0.05 mg/kg to target a heart rate reduction of at least 20%, based on tolerability.-Maximum dose: 6 months to less than 1 year old: 0.2 mg/kg orally twice a day, up to a total of 7.5 mg orally twice a day; 1 year or older: 0.3 mg/kg orally twice a day, up to a total of 7.5 mg orally twice a day.40 kg or more (tablets):-Initial dose: 2.5 mg orally twice a day with food; assess patient at 2-week intervals and adjust dose by 2.5 mg to target a heart rate reduction of at least 20%, based on tolerability.-Maximum dose: 7.5 mg orally twice a dayUse: Treatment of stable symptomatic heart failure due to dilated cardiomyopathy (DCM) in pediatric patients 6 months or older who are in sinus rhythm with an elevated heart rate.\n Detailed Ivabradine dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Ivabradine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\nMany drugs can affect ivabradine, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Ivabradine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nvery slow heartbeats;\nsevere headache, blurred vision, pounding in your neck or ears;\nracing heartbeats with dizziness, tiredness, or a lack of energy;\nchest tightness; or\nshortness of breath that is worse than usual.\nIf your baby is taking ivabradine, watch for symptoms of feeding problems, trouble breathing, or turning blue.\nIvabradine can cause a temporary brightness in your vision, especially during the first 2 months of treatment. This can make you see halos around lights, see colors within lights, or see multiple images while looking at an object. You may also see kaleidoscope colors or flashes of movement in certain parts of your vision. Sudden bright light can make these vision changes more noticeable. These effects usually go away as you continue taking ivabradine or after you stop taking it.\nCommon side effects may include:\nslow or irregular heartbeats;\nhigh blood pressure; or\nyour eyes may be more sensitive to light.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ivabradine side effects (more detail)\n','Ivabradine works by affecting your heart\'s electrical activity in order to slow the heart rate.\nIvabradine is used in adults with chronic heart failure, to help lower the risk of needing to be hospitalized when symptoms get worse.\nIvabradine is also used in children at least 6 months old who have stable heart failure caused by an enlarged heart.\nIvabradine may also be used for purposes not listed in this medication guide.\n','You should not use ivabradine if you have severe liver disease, very low blood pressure, a slow resting heart rate, a serious heart condition such as \"sick sinus syndrome\" or 3rd-degree \"AV block\" (unless you have a pacemaker), or if you depend on a pacemaker to control your heart rate.\nTell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.\nIvabradine may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.\nIvabradine can cause serious heart rhythm problems. Call your doctor at once if you have chest pressure, racing or pounding heartbeats, very slow heartbeats, weakness, tiredness, severe dizziness, or shortness of breath that is worse than usual.\nIf your baby is taking ivabradine, watch for symptoms of feeding problems, trouble breathing, or turning blue.\nBefore taking this medicine\nYou should not use ivabradine if you are allergic to it, or if you have:\na serious heart condition such as \"sick sinus syndrome\" or 3rd-degree \"AV block\" (unless you have a pacemaker);\nheart failure symptoms that recently got worse;\nvery low blood pressure;\na slow resting heart rate;\nsevere liver disease; or\nif you depend on a pacemaker to control your heart rate.\nSome medicines can cause unwanted or dangerous effects when used with ivabradine. Your doctor may need to change your treatment plan if you use any of the following drugs:\nan antibiotic or antifungal medicine;\nan antidepressant;\nantiviral medicine to treat hepatitis C or HIV/AIDS; or\nother heart medicine or blood pressure medication (such as amiodarone, digoxin, diltiazem, or verapamil).\nTell your doctor if you have any other heart problems not being treated with ivabradine.\nTaking ivabradine during pregnancy may harm an unborn baby or lead to premature birth. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.\nYou should not breastfeed while using  ivabradine.\nHow should I take ivabradine?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nIvabradine is usually taken 2 times per day with food. Avoid grapefruit or grapefruit juice.\nTell your doctor if you have trouble swallowing a ivabradine tablet.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Each plastic ampule is for one use only. Throw it away after one use, even if there is still medicine left inside.\nIf a child taking ivabradine spits outs the medicine shortly after taking, do not give another dose. Wait until the next scheduled dose time to give the medicine again.\nYou may also need to take another medicine called a beta-blocker. Use all medications as directed and read all medication guides you receive. Do not stop taking your medication or change your doses without your doctor\'s advice.\nYour heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).\nStore at room temperature away from moisture, heat, and light. Keep the ampules of liquid ivabradine in the foil pouch and use the medicine right away after opening.\nWhat happens if I miss a dose?\nSkip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Grapefruit may interact with ivabradine and lead to unwanted side effects. Avoid the use of grapefruit products.\nAvoid taking an herbal supplement containing St. John\'s wort.\nAvoid driving or hazardous activity until you know how  ivabradine will affect you. Your reactions could be impaired.\nAvoid sudden changes in the intensity of light around you, such as going outside in sunlight after being in a dark place. Allow your eyes time to adjust slowly to the light.\n'),(419,'ivermectin','Usual Adult Dose of Ivermectin for Onchocerciasis:\n0.15 mg/kg orally once every 12 months\nPatients with heavy ocular infection may require retreatment every 6 months. Retreatment may be considered at intervals as short as 3 months.\nDosage guidelines based on body weight:\n15 to 25 kg: 3 mg orally one time\n26 to 44 kg: 6 mg orally one time\n45 to 64 kg: 9 mg orally one time\n65 to 84 kg: 12 mg orally one time\n85 kg or more: 0.15 mg/kg orally one time\nUsual Adult Dose for Strongyloidiasis:\n0.2 mg/kg orally once\nIn immunocompromised (including HIV) patients, the treatment of strongyloidiasis may be refractory requiring repeated treatment (i.e., every 2 weeks) and suppressive therapy (i.e., once a month), although well-controlled studies are not available. Cure may not be achievable in these patients.\nDosage guidelines based on body weight:\n15 to 24 kg: 3 mg orally one time\n25 to 35 kg: 6 mg orally one time\n36 to 50 kg: 9 mg orally one time\n51 to 65 kg: 12 mg orally one time\n66 to 79 kg: 15 mg orally one time\n80 kg or more: 0.2 mg/kg orally one time\nUsual Adult Dose for Ascariasis:\n0.2 mg/kg orally once\nUsual Adult Dose for Cutaneous Larva Migrans:\n0.2 mg/kg orally once\nUsual Adult Dose for Filariasis:\n0.2 mg/kg orally once\nStudy (n=26,000)\nMass treatment in Papua, New Guinea:\nBancroftian filariasis: 0.4 mg/kg orally once yearly (with a single annual dose of diethylcarbamazine 6 mg/kg), for 4 to 6 years\nUsual Adult Dose for Scabies:\n0.2 mg/kg orally once, and repeated in 2 weeks\nIvermectin therapy may be combined with a topical scabicide.\nUsual Pediatric Dose for Filariasis:\nStudy (n=26,000)\nMass treatment in Papua, New Guinea:\nBancroftian filariasis:\n5 years or older: 0.4 mg/kg orally once yearly (with a single annual dose of diethylcarbamazine 6 mg/kg), for 4 to 6 years\n Detailed Ivermectin dosage information\nWhat happens if I miss a dose?\nSince ivermectin is usually given in a single dose, you may not be on a dosing schedule. If you are on a schedule, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with ivermectin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Ivermectin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to ivermectin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\neye pain or redness, puffy eyes, problems with your vision;\nsevere skin rash, itching, or rash with pus;\nconfusion, change in your mental status, balance problems, trouble walking;\nfever, swollen glands, stomach pain, joint pain, swelling in your hands or feet;\nfast heart rate, trouble breathing;\nloss of bladder or bowel control;\nneck or back pain, seizure (convulsions); or\na light-headed feeling, like you might pass out.\nCommon ivermectin side effects may include:\nheadache, muscle aches;\ndizziness;\nnausea, diarrhea; or\nmild skin rash.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ivermectin side effects (more detail)\n','Ivermectin is an anti-parasite medication.\nIvermectin is used to treat infections in the body that are caused by certain parasites.\nIvermectin is currently being investigated as a treatment for coronavirus SARS-CoV-2, which is the virus that causes COVID-19. The FDA has not approved ivermectin for use in treating or preventing COVID-19 in humans. The World Health Organization (WHO) recommend not to use ivermectin in patients with COVID-19, except in clinical trials.\nClick for further information on using ivermectin to treat COVID-19 and other prevention and investigational treatments.\n','You will need to have a stool exam after taking ivermectin to make sure the infection is gone. Some patients may need to take another dose of ivermectin to treat the infection.\nIvermectin may make you feel dizzy. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.\nBefore taking this medicine\nYou should not use ivermectin if you are allergic to it.\nTo make sure ivermectin is safe for you, tell your doctor if you have:\nliver or kidney disease; or\ncancer, HIV or AIDS, or other conditions that can weaken your immune system.\nIt is not known whether ivermectin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.\nIvermectin can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nIvermectin should not be given to a child who weighs less than 33 pounds (15 kg).\nHow should I take ivermectin?\nNever take ivermectin in larger amounts, or for longer than recommended by your doctor. Follow all directions on your prescription label.\nTake ivermectin on an empty stomach, at least 1 hour before or 2 hours after a meal.\nIvermectin is usually given as a single dose. Take this medicine with a full glass of water.\nTo effectively treat your infection, you may need to take ivermectin again several months to a year after your first dose.\nIf you have a weak immune system (caused by disease or by using certain medicine), you may need to take more than one dose of ivermectin. Some people who have a weak immune system need to take this medicine on a regular basis. Follow your doctor\'s instructions.\nTo make sure this medicine is working, you may need to provide frequent stool samples.\nStore this medicine at room temperature away from moisture and heat.\n','Drinking alcohol can increase certain side effects of ivermectin.\n'),(420,'jadenu','Take Jadenu exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nYour doctor may perform certain tests to make sure you do not have conditions that would prevent you from safely using Jadenu.\nTake Jadenu at the same time every day.\nYou may take this medicine on an empty stomach or with a small low-fat meal.\nSwallow the Jadenu tablet whole with a full glass of water. If you cannot swallow the tablet whole, you may crush the tablet and mix it with yogurt, applesauce, or other soft food.\nTo take Jadenu Sprinkles, open the packet and sprinkle the medicine into a spoonful of soft food.\nAfter mixing a crushed tablet or sprinkles with soft food, swallow the mixture right away without chewing. Do not save it for later use.\nYou may need frequent blood tests. Your kidney or liver function may also need to be checked every 6 months, and you may need a liver biopsy.\nStore at room temperature, away from moisture and heat.\n Detailed Jadenu dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can interact with deferasirox. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Jadenu drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Jadenu (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop using Jadenu and call your doctor at once if you have:\nproblems with vision or hearing;\nkidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath;\nliver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nlow blood cell counts - fever, chills, mouth sores, skin sores, pale skin, easy bruising, unusual bleeding, cold hands and feet, feeling light-headed or short of breath; or\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nSerious side effects may be more likely in older adults.\nCommon Jadenu side effects may include:\nnausea, vomiting, stomach pain;\ndiarrhea; or\nskin rash.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jadenu side effects (more detail)\n','Jadenu (deferasirox) binds to iron and removes it from the bloodstream.\nJadenu is usded in people 2 years of age and older who have an increased amount of iron in their blood for a long period of time (chronic), caused by repeated blood transfusions.\nJadenu is also used in certain people 10 years of age or older with thalassemia who have an increased amount of iron in their blood but who are not receiving regular blood transfusions.\nIt is not known if Jadenu is safe and effective when used with other medicines to treat an increased amount of iron in the blood.\n','You should not use Jadenu if you have severe kidney or liver disease, advanced cancer, a blood cell or bone marrow disorder, or low levels of platelets in your blood.\nDeferasirox can harm your liver or kidneys. Call your doctor at once if you have swelling, shortness of breath, pain in your upper stomach, loss of appetite, little or no urinating, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).\nJadenu may also cause stomach or intestinal bleeding. Call your doctor at once if you have symptoms of stomach bleeding such as bloody or tarry stools, or coughing up blood or vomit that looks like coffee grounds.\nBefore taking this medicine\nYou should not use Jadenu if you are allergic to deferasirox, or if you have:\nsevere liver or kidney disease;\nadvanced cancer;\na bone marrow disorder; or\nlow levels of platelets in your blood.\nTo make sure Jadenu is safe for you, tell your doctor if you have ever had:\nkidney disease;\nliver disease;\nanemia (low red blood cells);\ncancer (especially blood cell cancer such as leukemia);\na stomach ulcer;\nstomach or intestinal bleeding;\nvision or hearing problems; or\na weak immune system caused by disease (such as cancer, HIV, or AIDS), or by receiving steroids, chemotherapy, or radiation.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nJadenu can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.\nYou should not breast-feed while you are taking Jadenu.\n','Do not use other iron-chelating medicines such as deferoxamine (Desferal), unless your doctor has told you to.\nDo not take antacids that contain aluminum, such as Amphojel, Gaviscon, Maalox, Mi-Acid, Mylanta, Rulox, and others.\nJadenu may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\n'),(421,'jakafi','Usual Adult Dose for Myeloproliferative Disorder:\nInitial Dose:\n-Platelets greater than 200 x 10(9)/L: 20 mg orally twice a day\n-Platelets 100 to 200 x 10(9)/L: 15 mg orally twice a day\n-Platelets 50 to less than 100 x 10(9)/L: 5 mg orally twice a day\nMaximum dose:\n-Starting platelets 100 x 10(9)/L or greater: 25 mg twice a day\n-Starting platelets 50 to less than 100 x 10(9)/L: 10 mg twice a day\nDuration of therapy: 6 months if no spleen reduction or symptom improvement\nComments:\n-Doses may be titrated based on safety and efficacy.\n-If efficacy is considered insufficient and platelet and neutrophil counts are adequate, doses may be increased by a maximum of 5 mg twice daily.\n-The starting dose should not be increased within the first four weeks of treatment and thereafter no more frequently than at 2 week intervals.\nUses: Intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis\n Detailed Jakafi dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nTell your doctor about all your other medicines, especially fluconazole.\nThis list is not complete and many other drugs may interact with ruxolitinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Jakafi drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Jakafi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome side effects may be similar to the symptoms of myelofibrosis. Call your doctor at once if you have:\nblisters or painful skin rash;\nchanges in the size, shape, or color of a mole or skin lesion;\nproblems with speech, thought, vision, or muscle movement (these symptoms may start gradually and get worse quickly);\nnausea, vomiting, weakness, general ill feeling;\npain or burning when you urinate;\nlow blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or\nsigns of tuberculosis: fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired.\nCommon Jakafi side effects include:\nlow blood cell counts;\nfluid retention;\ndiarrhea;\ndizziness; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jakafi side effects (more detail)\n','Jakafi (ruxolitinib) works by blocking certain enzymes in the body that affect blood cell production.\nJakafi is used in adults to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that that affect your body\'s ability to produce blood cells.\nJakafi is also used to treat acute graft versus host disease (GVHD) in adults and children 12 years of age and older who have taken corticosteroids and they did not work well enough.\nJakafi is usually given after other treatments have failed.\n','You should not use Jakafi if you are allergic to ruxolitinib, or if you have severe kidney disease.\nBefore you take this medicine, tell your doctor if you have liver or kidney disease, if you are on dialysis, or if you are pregnant.\nYou should not breast-feed while you are using this medicine.\nTo be sure Jakafi is helping your condition and not causing harmful effects, your blood will need to be tested often. This will help your doctor determine the best dose for you to use. When you first start taking this medicine, your blood will need to be tested every 2 to 4 weeks. Do not miss any follow-up visits to your doctor.\nGrapefruit and grapefruit juice may interact with Jakafi and can affect the amount of the medication in your blood. Discuss the use of grapefruit products with your doctor.\nFollow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use Jakafi if you are allergic to ruxolitinib.\nTell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.\nTo make sure Jakafi is safe for you, tell your doctor if you have ever had:\nany type of chronic infection;\nkidney disease (or if you are on dialysis);\nliver disease (especially hepatitis B);\nskin cancer; or\nhigh cholesterol or triglycerides (types of fat in the blood).\nUsing Jakafi may increase your risk of developing skin cancer. Talk to your doctor about this risk and what skin symptoms to watch for.\nIt is not known whether ruxolitinib will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nYou should not breastfeed while you are using Jakafi, and for at least 2 weeks after your last dose.\nJakafi is not approved to treat myelofibrosis or polycythemia vera in anyone younger than 18 years old.\nHow should I take Jakafi?\nTake Jakafi exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nYour doctor may occasionally change your dose. You will need frequent medical tests to help your doctor determine the best dose. When you first start taking Jakafi, your blood will need to be tested every 2 to 4 weeks.\nYou may take Jakafi with or without food. The Jakafi tablet can also be given through a nasogastric (NG) feeding tube.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nStore at room temperature away from moisture and heat.\nYou should not stop using Jakafi suddenly. Follow your doctor\'s instructions about tapering your dose.\nYou may be given other medications to help prevent infection. Keep using these medicines for as long as your doctor has prescribed.\n','Grapefruit may interact with ruxolitinib and lead to unwanted side effects. Avoid the use of grapefruit products.\n'),(422,'jalyn','Usual Adult Dose for Benign Prostatic Hyperplasia:\nDutasteride 0.5 mg-Tamsulosin 0.4 mg orally once a day approximately 30 minutes after the same meal each day\nUse: Treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate.\n Detailed Jalyn dosage information\nWhat happens if I miss a dose?\nTake your dose as soon as you can, but only within 30 minutes after a meal. Skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nCall your doctor if you miss your doses for several days in a row.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may interact with dutasteride and tamsulosin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Jalyn drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Jalyn (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nStop using this medicine and call your doctor at once if you have:\na light-headed feeling, like you might pass out; or\npenis erection that is painful or lasts 4 hours or longer.\nCommon Jalyn side effects may include:\ndecreased libido (sex drive);\ndecreased amount of semen released during sex;\nimpotence (trouble getting or keeping an erection);\nbreast tenderness or enlargement;\ndizziness; or\nrunny nose.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jalyn side effects (more detail)\n','Jalyn contains a combination of dutasteride and tamsulosin. Dutasteride prevents testosterone from converting to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH).\nTamsulosin relaxes the muscles in the prostate and bladder neck, making it easier to urinate.\nJalyn is used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate.\n','Jalyn should never be handled or taken by a woman, a child, or a teenager. Dutasteride can be absorbed through the skin. This medication can cause birth defects if a woman is exposed to it during pregnancy. The capsules should not be handled by a woman who is pregnant or who may become pregnant. If a woman accidentally comes into contact with the medication from a leaking capsule, wash the area with soap and water right away. Do not donate blood while taking Jalyn and for at least 6 months after your treatment ends. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride.\nYou should not use Jalyn if you are allergic to dutasteride (Avodart) or tamsulosin (Flomax). Do not take this medicine if you are also taking alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin).\nThere are many other drugs that can interact with dutasteride and tamsulosin. Tell your doctor about all medications you use.\nJalyn should never be taken by a woman, a child, or a teenager.\nJalyn may increase your risk of developing prostate cancer. Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using this medicine.\nTamsulosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Jalyn before surgery unless your surgeon tells you to.\nBefore taking this medicine\nYou should not use Jalyn if you are allergic to dutasteride, finasteride, or tamsulosin.\nYou should not take this medicine while you are taking tamsulosin (Flomax) or similar medicines, such as alfuzosin, doxazosin, prazosin, silodosin, or terazosin.\nJalyn should never be taken by a woman, a child, or a teenager. Dutasteride can be absorbed through the skin, and women or children should not be permitted to handle Jalyn capsules.\nThis medicine is not for use by women. This medicine can cause birth defects. The capsules should not be handled by a woman who is pregnant or who may become pregnant.\nIf a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away.\nTo make sure Jalyn is safe for you, tell your doctor if you have ever had:\nhigh or low blood pressure;\nliver or kidney disease;\nprostate cancer; or\nan allergy to sulfa drugs.\nUsing this medicine may increase your risk of developing prostate cancer. Ask your doctor about this risk.\nJalyn can affect your pupils. If you need eye surgery, tell the surgeon about your use of this medicine, even if you no longer take it.\nHow should I take Jalyn?\nTake Jalyn exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nTake this medicine 30 minutes after a meal, at the same time each day.\nSwallow the Jalyn capsule whole and do not crush, chew, break, or open it.\nYou will need medical tests to check your prostate specific antigen (PSA).\nStore at room temperature away from moisture and heat.\n','Avoid taking medicines for erectile dysfunction (sildenafil, avanafil, Viagra, Cialis, and others).\nDo not donate blood while taking this medicine and for at least 6 months after your last dose. Dutasteride could cause birth defects if a pregnant women receives a transfusion with blood that contains this medicine.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(423,'jantoven','Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take Jantoven in larger or smaller amounts or for longer than your doctor tells you to.\nTake Jantoven at the same time every day, with or without food. Never take a double dose.\nJantoven can make it easier for you to bleed. Seek emergency help if you have any bleeding that will not stop.\nYou will need frequent \"INR\" or prothrombin time tests (to measure your blood-clotting time and determine your Jantoven dose). You must remain under the care of a doctor while taking this medicine.\nIf you receive Jantoven in a hospital, call or visit your doctor 3 to 7 days after you leave the hospital. Your INR will need to be tested at that time. Do not miss any follow-up appointments.\nTell your doctor if you are sick with diarrhea, fever, chills, or flu symptoms, or if your body weight changes.\nYou may need to stop taking Jantoven 5 to 7 days before having any surgery, dental work, or a medical procedure. Call your doctor for instructions.\nWear a medical alert tag or carry an ID card stating that you take Jantoven. Any medical care provider who treats you should know that you are taking  Jantoven.\nStore at room temperature away from heat, moisture, and light.\n Detailed Jantoven dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause excessive bleeding.\n','Many drugs (including some over-the-counter medicines and herbal products) can affect your INR and may increase the risk of bleeding if you take them with Jantoven. Not all possible drug interactions are listed in this medication guide. It is very important to ask your doctor and pharmacist before you start or stop using any other medicine, especially:\nother medicines to prevent blood clots;\nan antibiotic or antifungal medicine;\nsupplements that contain vitamin K; or\nherbal (botanical) products--coenzyme Q10, cranberry, echinacea, garlic, ginkgo biloba, ginseng, goldenseal, or St. John\'s wort.\nThis list is not complete and many other drugs can interact with Jantoven. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.\n Jantoven drug interactions (more detail)\nDoes Jantoven interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nJantoven increases your risk of bleeding, which can be severe or life-threatening. Call your doctor at once if you have any signs of bleeding such as:\nsudden headache, feeling very weak or dizzy;\nswelling, pain, unusual bruising;\nbleeding gums, nosebleeds;\nbleeding from wounds or needle injections that will not stop;\nheavy menstrual periods or abnormal vaginal bleeding;\nblood in your urine, bloody or tarry stools; or\ncoughing up blood or vomit that looks like coffee grounds.\nClots formed by Jantoven may block normal blood flow, which could lead to tissue death or amputation of the affected body part. Get medical help at once if you have:\npain, swelling, hot or cold feeling, skin changes, or discoloration anywhere on your body; or\nsudden and severe leg or foot pain, foot ulcer, purple toes or fingers.\nBleeding is the most common side effect of warfarin.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jantoven side effects (more detail)\n','Jantoven is an anticoagulant (blood thinner). This medicine reduces the formation of blood clots.\nJantoven is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.\nJantoven may also be used for purposes not listed in this medication guide.\n','You should not take Jantoven if you are prone to bleeding because of a medical condition, if you have an upcoming surgery, or if you need a spinal tap or epidural. Do not take this medicine if you cannot take it on time every day.\nJantoven increases your risk of severe or fatal bleeding, especially if you have certain medical conditions, if you are 65 or older, or if you have had a stroke, or bleeding in your stomach or intestines. Seek emergency help if you have any bleeding that will not stop.\nCall your doctor at once if you have other signs of bleeding such as: swelling, pain, feeling very weak or dizzy, unusual bruising, bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nMany other drugs can increase your risk of bleeding when used with Jantoven. Tell your doctor about all medicines you have recently used.\nAvoid making any changes in your diet without first talking to your doctor. Some foods can make Jantoven less effective.\nBefore taking this medicine\nYou should not take Jantoven if you are allergic to it, or if:\nyou have very high blood pressure;\nyou recently had or will have surgery on your brain, spine, or eye;\nyou undergo a spinal tap or spinal anesthesia (epidural); or\nyou cannot take Jantoven on time every day.\nYou also should not take Jantoven if you are are prone to bleeding because of a medical condition, such as:\na blood cell disorder (such as low red blood cells or low platelets);\nulcers or bleeding in your stomach, intestines, lungs, or urinary tract;\nan aneurysm or bleeding in the brain; or\nan infection of the lining of your heart.\nDo not take Jantoven if you are pregnant, unless your doctor tells you to. This medicine can cause birth defects, but preventing blood clots may outweigh any risks to the baby. If you are not pregnant, use effective birth control to prevent pregnancy while taking this medicine and for at least 1 month after your last dose. Tell your doctor right away if you become pregnant.\nJantoven can make you bleed more easily, especially if you have ever had:\nhigh blood pressure or serious heart disease;\nkidney disease;\ncancer or low blood cell counts;\nan accident or surgery;\nbleeding in your stomach or intestines;\na stroke; or\nif you are 65 or older.\nTo make sure Jantoven is safe for you, tell your doctor if you have ever had:\ndiabetes;\ncongestive heart failure;\nliver disease, kidney disease (or if you are on dialysis);\na hereditary clotting deficiency; or\nlow blood platelets after receiving heparin.\nIt is not known whether warfarin passes into breast milk. Watch for signs of bruising or bleeding in the baby if you take warfarin while you are breast-feeding a baby.\n','Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. You may still bleed more easily for several days after you stop taking Jantoven.\nAvoid making any changes in your diet without first talking to your doctor. Foods that are high in vitamin K (liver, leafy green vegetables, or vegetable oils) can make Jantoven less effective. If these foods are part of your diet, eat a consistent amount on a weekly basis.\nGrapefruit juice, cranberry juice, noni juice, and pomegranate juice may interact with Jantoven and lead to unwanted side effects. Avoid the use of these juice products while taking this medicine.\nAvoid drinking alcohol.\nAsk your doctor before using any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. These medicines may affect blood clotting and may also increase your risk of stomach bleeding.\n'),(424,'janumet','Take Janumet exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nTake Janumet with meals.\nDo not crush, chew, or break an extended-release tablet. Swallow it whole.\nJanumet tablets may not completely dissolve in the body. Part of the tablet may appear in your stool. This is a normal side effect of Janumet and will not make the medicine less effective.\nCall your doctor if you see a tablet in your stool several times.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nJanumet is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nYour blood will need to be tested often.\nStore at room temperature away from moisture and heat.\n Detailed Janumet dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure).\n','Many drugs can interact with metformin and sitagliptin. Some drugs can affect how well Janumet controls your blood sugar. Other drugs may increase your risk of lactic acidosis.\nTell your doctor if you use any of the following medications before taking Janumet:\nanti-seizure medications (including topiramate, zonisamide, acetazolamide, phenytoin, and others)\nanti-viral medications for HIV or AIDS;\nantipsychotic medications (especially chlorpromazine, prochlorperazine, thioridazine, and others);\ndichlorphenamide;\nantacid medications including cimetidine;\nranolazine;\nvandetanib;\ncorticosteroid medications (such as prednisone),\nestrogen-containing medications including birth control pills or hormone replacement;\nheart or blood pressure medications (especially digoxin, diuretics or water pills, calcium channel blockers, and others); or\nother diabetes medications including insulin, sulfonylureas, or others\nNot all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using. Give a list of all your medicines to any healthcare provider who treats you.\nDate modified:\n Janumet drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Janumet: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop taking this medicine and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.\nSome people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal. Stop taking this medicine and get emergency medical help if you have even mild symptoms such as:\nunusual muscle pain;\nfeeling cold;\ntrouble breathing;\nfeeling dizzy, light-headed, tired, or very weak;\nstomach pain, nausea with vomiting; or\nslow or irregular heartbeat.\nCall your doctor at once if you have any of these serious side effects:\nitching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints;\nlittle or no urinating; or\nshortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain; or\nsigns of low blood sugar, including headache, sleepiness, dizziness, sweating, feeling jittery, hunger, or fast heartbeat.\nCommon Janumet side effects may include:\nlow blood sugar (if you also use insulin or another oral diabetes medication);\nupset stomach, indigestion, gas, diarrhea, nausea, vomiting;\nheadache, weakness; or\ncold symptoms such as runny or stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Janumet side effects (more detail)\n','Janumet contains a combination of metformin and sitagliptin. Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels.\nMetformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.\nJanumet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.\nJanumet is not used to treat type 1 diabetes.\n','You should not use Janumet if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).\nJanumet may cause a serious condition called lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.\nJanumet may also lead to a serious condition called pancreatitis. Call your doctor right away if you have severe stomach pains with or without vomiting.\nBefore taking this medicine\nYou should not use Janumet if you are allergic to metformin or sitagliptin (Januvia), or if you have severe kidney disease.\nTo make sure Janumet is safe for you, tell your doctor if you have ever had:\nkidney disease (your kidney function may need to be checked before and while you are taking this medicine);\nliver disease;\nheart disease;\npancreatitis;\nhigh triglycerides (a type of fat in the blood);\ngallstones; or\nalcoholism.\nSome people taking metformin develop a serious condition called lactic acidosis. This may be more likely if you have liver or kidney disease, congestive heart failure, surgery, a heart attack or stroke, a severe infection, if you are 65 or older, if you are dehydrated, or if you drink a lot of alcohol. Talk with your doctor about your risk.\nIf you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Janumet. Be sure your caregivers know ahead of time that you are using this medication.\nFollow your doctor\'s instructions about using Janumet if you are pregnant or you become pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Having high blood sugar may cause complications in both the mother and the baby.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Your dose needs may also be different while you are breastfeeding.\nJanumet is not approved for use by anyone younger than 18 years old.\n','Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.\n'),(425,'janumet-xr','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nTake Janumet XR with meals.\nSwallow the tablet whole and do not crush, chew, or break it.\nSome tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.\nCall your doctor if you see a tablet in your stool several times.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nJanumet XR is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nYour blood will need to be tested often.\nStore at room temperature away from moisture and heat.\n Detailed Janumet XR dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the medicine (with food) as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure).\n','Many drugs can affect Janumet XR, making this medicine less effective or increasing your risk of lactic acidosis. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Janumet XR drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop taking  Janumet XR and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.\nSome people using metformin develop lactic acidosis, which can be fatal. Get emergency medical help if you have even mild symptoms such as:\nunusual muscle pain;\nfeeling cold;\ntrouble breathing;\nfeeling dizzy, light-headed, tired, or very weak;\nstomach pain, vomiting; or\nirregular heart rate.\nCall your doctor at once if you have any of these serious side effects:\nsevere autoimmune reaction--itching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints;\nlittle or no urinating; or\nsymptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nCommon side effects may include:\nlow blood sugar (if you also use insulin or another oral diabetes medication);\nupset stomach, indigestion, gas, diarrhea, nausea, vomiting;\nheadache, weakness; or\ncold symptoms such as runny or stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Janumet XR side effects (more detail)\n','Janumet XR are oral diabetes medicines that help control blood sugar levels.\nMetformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.\nJanumet XR is a combination medicine that is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.  Janumet XR is not for treating type 1 diabetes.\nJanumet XR may also be used for purposes not listed in this medication guide.\n','You should not use this medicine if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).\nYou may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.\nBefore taking this medicine\nYou should not use  Janumet XR if you are allergic to metformin or sitagliptin (Januvia), or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).\nTell your doctor if you have ever had:\nkidney disease (your kidney function may need to be checked before and while you are taking this medicine);\nliver disease;\nheart disease;\npancreatitis;\nhigh triglycerides (a type of fat in the blood);\ngallstones; or\nalcoholism.\nYou may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.\nIf you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Janumet XR. Be sure your caregivers know ahead of time that you are using this medication.\nFollow your doctor\'s instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nMetformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nThis medicine is not approved for use by anyone younger than 18 years old.\n','Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.\n'),(426,'januvia','Usual Adult Dose for Diabetes Type 2:\nUsual dose: 100 mg orally once a day\nComments: When used in combination with an insulin secretagogue (e.g. sulfonylurea) or insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.\nUse: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.\n Detailed Januvia dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).\n','Januvia may not work as well when you use other medicines at the same time. Many other drugs can also affect blood sugar control.\nYou may be more likely to have low blood sugar if you also use insulin.\nOther drugs may affect sitagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\nThis includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all medicines you start or stop using.\n Januvia drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Januvia (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop taking Januvia and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, with or without vomiting.\nCall your doctor at once if you have:\nsevere autoimmune reactionitching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints;\nlittle or no urination; or\nsymptoms of heart failureshortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nCommon Januvia side effects may include:\nlow blood sugar;\nheadache; or\nrunny or stuffy nose, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Januvia side effects (more detail)\n','Januvia (sitagliptin) is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.\nJanuvia is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.\nJanuvia is not for treating type 1 diabetes.\n','You should not use Januvia if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).\nCall your doctor if you have symptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nStop taking Januvia and call your doctor if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, with or without vomiting.\nBefore taking this medicine\nYou should not use Januvia if you are allergic to sitagliptin, or if you have diabetic ketoacidosis (call your doctor for treatment with insulin).\nTell your doctor if you have ever had:\nkidney disease (or if you are on dialysis);\nheart problems;\npancreatitis;\nhigh triglycerides (a type of fat in the blood);\ngallstones; or\nalcoholism.\nFollow your doctor\'s instructions about using Januvia if you are pregnant or you become pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester. Having high blood sugar may cause complications in both the mother and the baby.\nYour name may need to be listed on a Januvia pregnancy registry when you start using this medicine.\nIt may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.\nJanuvia is not approved for use by anyone younger than 18 years old.\nHow should I take Januvia?\nTake Januvia exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYou may take Januvia with or without food. Follow your doctor\'s instructions.\nYour blood sugar may need to be checked often, and you may need other blood tests at your doctor\'s office.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nJanuvia is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture, heat, and light.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(427,'jardiance','Jardiance is usually taken once per day in the morning. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nYou may take Jardiance with or without food.\nCall your doctor if you are sick with vomiting or diarrhea, if you consume less food or fluid than usual, or if you are sweating more than usual.\nYour blood sugar will need to be checked often, and you may also need to test the level of ketones in your urine. Empagliflozin can cause life-threatening ketoacidosis (too much acid in the blood). Even if your blood sugar is normal, contact your doctor if a urine test shows that you have ketones in the urine.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using empagliflozin.\nJardiance is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture and heat.\n Detailed Jardiance dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\ninsulin or other oral diabetes medications; or\na diuretic or \"water pill.\"\nThis list is not complete. Other drugs may interact with empagliflozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Jardiance drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Jardiance: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSeek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.\nCall your doctor at once if you have:\nlittle or no urination;\ndehydration symptoms - dizziness, weakness, feeling light-headed (like you might pass out);\nketoacidosis (too much acid in the blood) - nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing; or\nsigns of a bladder infection - pain or burning when you urinate, increased urination, blood in your urine, fever, pain in your pelvis or back.\nOlder adults may be more likely to have side effects from this medicine.\nCommon Jardiance side effects may include:\nbladder infection; or\nvaginal yeast infection.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jardiance side effects (more detail)\n','Jardiance (empagliflozin) is an oral diabetes medicine that helps control blood sugar levels. Empagliflozin works by helping the kidneys get rid of glucose from your bloodstream.\nJardiance is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.\nJardiance is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.\nJardiance is not for treating type 1 diabetes.\n','You should not use Jardiance if you have severe kidney disease or if you are on dialysis, or if you have diabetic ketoacidosis.\nTaking Jardiance can make you dehydrated, which could cause you to feel weak or dizzy (especially when you stand up).\nJardiance can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don\'t feel well.\nBefore taking this medicine\nYou should not use Jardiance if you are allergic to empagliflozin, or if you have:\nsevere kidney disease (or if you are on dialysis).\nTo make sure Jardiance is safe for you, tell your doctor if you have ever had:\nliver or kidney disease;\nbladder infections or other urination problems;\nlow blood pressure;\nheart problems;\nproblems with your pancreas, including surgery;\nif you drink alcohol often; or\nif you are on a low salt diet.\nFollow your doctor\'s instructions about using Jardiance if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nYou should not use Jardiance during the second or third trimester of pregnancy.\nYou should not breastfeed while using this medicine.\nJardiance is not approved for use by anyone younger than 18 years old.\n','Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.\n'),(428,'jasmiel','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms with spermicide, when you first start using this medication.\nTake one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You could get pregnant if you do not take one pill daily.\nYou may have breakthrough bleeding, especially during the first 3 months. Tell your doctor if this bleeding continues or is very heavy.\nIf you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using this medicine.\nStore at room temperature away from moisture and heat.\n Detailed Jasmiel dosage information\nWhat happens if I miss a dose?\nFollow the patient instructions provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Missing a pill increases your risk of becoming pregnant.\nIf you miss 1 active pill, take 2 pills on the day that you remember. Then take 1 pill per day for the rest of the pack.\nIf you miss 2 active pills in a row in Week 1 or 2, take 2 pills per day for 2 days in a row. Then take 1 pill per day for the rest of the pack. Use back-up birth control for at least 7 days following the missed pills.\nIf you miss 2 active pills in a row in Week 3, throw out the rest of the pack and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.\nIf you miss 3 active pills in a row in Week 1, 2, or 3, throw out the rest of the pack and start a new pack on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.\nIf you miss 2 or more pills, you may not have a period during the month. If you miss a period for 2 months in a row, call your doctor because you might be pregnant.\nIf you miss a reminder pill, throw it away and keep taking 1 reminder pill per day until the pack is empty.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may cause nausea or vaginal bleeding.\n','Other drugs may interact with drospirenone and ethinyl estradiol, including prescription and over-the-counter medicines, vitamins, and herbal products. Some drugs can make  Jasmiel less effective, which may result in pregnancy. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Jasmiel drug interactions (more detail)\nDoes Jasmiel interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using birth control pills and call your doctor at once if you have:\nsigns of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;\nsigns of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;\nheart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;\nliver problems--loss of appetite, upper stomach pain, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nincreased blood pressure--severe headache, blurred vision, pounding in your neck or ears;\nswelling in your hands, ankles, or feet;\na change in the pattern or severity of migraine headaches; or\nsymptoms of depression--sleep problems, weakness, tired feeling, mood changes.\nCommon side effects may include:\nnausea, vomiting;\nbreast tenderness;\nheadache, mood changes, feeling tired or irritable;\nweight gain; or\nchanges in your menstrual periods, decreased sex drive.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jasmiel side effects (more detail)\n','Jasmiel is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary).  Jasmiel also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.\nJasmiel is used as contraception to prevent pregnancy. This medicine is also used to treat moderate acne in women who are at least 14 years old and have started having menstrual periods, and who wish to use birth control pills.\nYaz is also used to treat the symptoms of premenstrual dysphoric disorder (PMDD), such as anxiety, depression, irritability, trouble concentrating, lack of energy, sleep or appetite changes, breast tenderness, joint or muscle pain, headache, and weight gain.\nJasmiel may also be used for purposes not listed in this medication guide.\n','Do not use if you are pregnant or if you recently had a baby.\nYou should not take this medicine if you have: an adrenal gland disorder, kidney disease, uncontrolled high blood pressure, heart disease, coronary artery disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, jaundice caused by pregnancy or birth control pills, or cancer of the breast, uterus/cervix, or vagina.\nTaking this medicine can increase your risk of blood clots, stroke, or heart attack.\nSmoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take this medicine if you smoke and are over 35 years old.\nBefore taking this medicine\nTaking  Jasmiel can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking birth control pills. Your risk is also high when you restart birth control pills after not taking them for 4 weeks or longer.\nSmoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not take this medicine if you smoke and are over 35 years old.\nDo not use if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant, or if you miss 2 menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking this medicine.\nYou should not take this medicine if you have:\nan adrenal gland disorder;\nkidney disease;\nuntreated or uncontrolled high blood pressure;\nheart disease (coronary artery disease, history of heart attack, stroke, or blood clot);\nan increased risk of having blood clots due to a heart problem or a hereditary blood disorder;\ncirculation problems (especially if caused by diabetes);\na history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;\nunusual vaginal bleeding that has not been checked by a doctor;\nliver disease or liver cancer;\nsevere migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;\na history of jaundice caused by pregnancy or birth control pills;\nif you smoke and are over 35 years old; or\nif you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir (Technivie).\nTell your doctor if you have ever had:\nheart problems, high blood pressure, or if you are prone to having blood clots;\nhigh levels of potassium in your blood;\nhigh cholesterol or triglycerides, or if you are overweight;\ndepression;\nliver or kidney disease;\nunderactive thyroid, diabetes, gallbladder disease; or\na migraine headache.\nThe hormones in this medicine can pass into breast milk and may harm a nursing baby. This medicine may also slow breast milk production. Do not use if you are breast feeding.\n','Do not smoke while taking  Jasmiel, especially if you are older than 35 years of age.\nThis medicine will not protect you from sexually transmitted diseases, including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.\n'),(429,'jatenzo','Take Jatenzo exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nYour doctor will perform a blood test to make sure Jatenzo is the right treatment for your condition.\nJatenzo is usually taken 1 time in the morning and 1 time in the evening. Follow your doctor\'s dosing instructions very carefully.\nAlways take this medicine with food.\nYou will need frequent blood tests and your blood pressure will need to be checked often. Your next dose may be delayed based on the results.\nMisuse of Jatenzo can cause dangerous or irreversible effects, such as enlarged breasts, small testicles, infertility, high blood pressure, heart attack, stroke, liver disease, bone growth problems, addiction, and mental effects such as aggression and violence. Stealing, selling, or giving away this medicine is against the law.\nStore at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.\n Detailed Jatenzo dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\ninsulin;\nblood pressure medications;\nmedicine to treat pain, cough, or cold symptoms;\na blood thinner - warfarin, Coumadin, Jantoven; or\nsteroid medicine - prednisone, dexamethasone, and others.\nThis list is not complete. Other drugs may interact with testosterone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Jatenzo drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Jatenzo: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nJatenzo can increase your blood pressure, which can increase your risk of heart attack, stroke, or death. You may need to stop using Jatenzo or start taking blood pressure medication.\nCall your doctor at once if you have:\nswelling in your feet, ankles or legs;\npain or swelling in your breasts;\nbreathing problems during sleep (breathing may stop);\nunusual changes in mood or behavior, new or worsening depression, thoughts about hurting yourself;\nliver problems - nausea, vomiting, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes);\nsigns of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;\nsigns of a blood clot deep in the body - pain, swelling, warmth, or redness in your leg; or\nworsening symptoms of an enlarged prostate - increased urination, a weak stream of urine, an urgent need to urinate, or loss of bladder control.\nCommon Jatenzo side effects may include:\nincreased red blood cell counts;\nan enlarged prostate;\nerections that are more frequent or that last longer than usual;\nincreased blood pressure;\nnausea, heartburn, burping;\ndiarrhea;\nheadache; or\nswelling in your lower legs.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jatenzo side effects (more detail)\n','Jatenzo is a liquid filled capsule containing testosterone. Testosterone is a naturally occurring sex hormone produced in a man\'s testicles. Small amounts of testosterone are also produced in a woman\'s ovaries and adrenal system.\nJatenzo is a prescription medicine used as a hormone replacement therapy in adult men with certain medical conditions that cause low or no testosterone levels.\nJatenzo will not enhance athletic performance and should not be used for that purpose.\nIt is not known if Jatenzo is safe or effective in children younger than 18 years old. Improper use of testosterone may affect bone growth in children.\n','You should not be treated with Jatenzo if you have prostate cancer, male breast cancer, or low testosterone due to getting older.\nTestosterone can increase your blood pressure, which can increase your risk of heart attack, stroke, or death. You may need to stop using Jatenzo or start taking blood pressure medication.\nJatenzo should not be used to enhance athletic performance.\nBefore taking this medicine\nYou should not use Jatenzo if you are allergic to testosterone, or if you have:\nmale breast cancer;\nprostate cancer; or\nlow testosterone due to getting older.\nAlthough Jatenzo is for use only in men, testosterone can harm an unborn baby and should not be used by a pregnant woman.\nTo make sure Jatenzo is safe for you, tell your doctor if you have ever had:\nheart problems;\nhigh blood pressure;\nsleep apnea (breathing stops during sleep);\nan enlarged prostate and urination problems;\nliver or kidney disease;\ndepression, anxiety, a mood disorder, suicidal thoughts or actions; or\nincreased hematocrit or hemoglobin levels on a blood test.\nUsing Jatenzo may increase your risk of developing prostate cancer. Ask your doctor about this risk.\nTestosterone can lower your sperm count, which may affect fertility (your ability to have children).\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(430,'jemperli',NULL,NULL,'Jemperli can cause serious side effects. See Important information.\nThe most common side effects include: tiredness and weakness, nausea, diarrhea, low red blood count (anemia), and constipation.\nThese are not all the possible side effects. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800­-FDA-1088.\nGeneral information about the safe and effective use of Jemperli.\nMedicines are sometimes prescribed for purposes other than those listed in a Medication Guide. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider for information that is written for healthcare professionals.\nWhat are the ingredients in Jemperli?\nActive ingredient: dostarlimab-gxly\nInactive ingredients: citric acid monohydrate, L-arginine hydrochloride, polysorbate 80, sodium chloride, trisodium citrate dihydrate, and Water for Injection.\n','Jemperli is a prescription medicine used to treat adults with a kind of uterine cancer called endometrial cancer. Jemperli may be used when:\nyour tumor has been shown by a laboratory test to be mismatch repair deficient (dMMR), and\nyour cancer has returned, or it has spread or cannot be removed by surgery (advanced cancer), and\nyou have received chemotherapy that contains platinum and it did not work or is no longer working.\nIt is not known if this medicine is safe and effective in children.\n','Jemperli is a medicine that may treat certain cancers by working with your immune system.\nJemperli can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. These problems may happen anytime during treatment or even after your treatment has ended.\nCall or see your healthcare provider right away if you develop any symptoms of the following problems or if these symptoms get worse:\nLung problems (pneumonitis). Symptoms of pneumonitis may include:\nnew or worsening cough\nchest pain\nshortness of breath\nIntestinal problems (colitis) that can lead to tears or holes in your intestine. Signs and symptoms of colitis may include:\ndiarrhea or more bowel movements than usual\nstools that are black, tarry, sticky, or have blood or mucus\nsevere stomach-area (abdomen) pain or tenderness\nLiver problems, including hepatitis. Signs and symptoms of liver problems may include:\nyellowing of your skin or the whites of your eyes\nnausea or vomiting\npain on the right side of your stomach area (abdomen)\ndark urine (tea colored)\nbleeding or bruising more easily than normal\nHormone gland problems (especially the adrenal glands, pituitary, thyroid, and pancreas). Signs and symptoms that your hormone glands are not working properly may include:\nheadaches that will not go away or unusual headaches\nextreme weakness\ndizziness and fainting\nvision changes\nrapid heartbeat\nincreased sweating\nweight gain or weight loss\nfeeling more hungry or thirsty than usual\nchanges in mood or behavior, such as decreased sex drive, irritability, or forgetfulness\nhair loss\nconstipation\nyour voice gets deeper\nvery low blood pressure\nurinating more often than usual\nnausea and vomiting\nstomach-area (abdomen) pain\nfeeling cold\nKidney problems, including nephritis and kidney failure. Signs of kidney problems may include:\nchange in the amount or color of your urine\nblood in your urine\nswelling in your ankles\nloss of appetite\nSkin problems. Signs of skin problems may include:\nrash\nitching\nfever or flu-like symptoms\nswollen lymph nodes\nblisters, peeling, or skin sores\npainful sores or ulcers in your mouth or in your nose, throat, or genital area\nProblems in other organs. Signs and symptoms of these problems may include:\nheadache\ntiredness or weakness\nsleepiness\nchanges in heartbeat, such as beating fast, or seeming to skip a beat, or pounding sensation\nconfusion, fever, muscle weakness, balance problems, nausea, vomiting, stiff neck, memory problems, or seizures (encephalitis)\nswollen lymph nodes, rash or tender lumps on skin, cough, shortness of breath, vision changes, or eye pain (sarcoidosis)\nseeing or hearing things that are not there (hallucinations)\nsevere or persistent muscle pain\nsevere muscle weakness\nlow red blood cells (anemia)\nbruises on the skin or bleeding\nchanges in eyesight\nInfusion reactions that can sometimes be severe and life-threatening. Signs and symptoms of infusion reactions may include:\nchills or shaking\nshortness of breath or wheezing\nitching or rash\nflushing\ndizziness\nfever\nfeeling like passing out\nComplications, including graft-versus-host-disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be severe and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with Jemperli. Your healthcare provider will monitor you for the following signs and symptoms: skin rash, liver inflammation, stomach area (abdominal) pain, and diarrhea.\nGetting medical treatment right away may help keep these problems from becoming more serious.\nYour healthcare provider will check you for these problems during treatment. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment, if you have severe side effects.\nBefore receiving Jemperli\nBefore you receive Jemperli, tell your healthcare provider if you have any medical conditions, including if you:\nhave immune system problems.\nhave lung or breathing problems.\nare pregnant or plan to become pregnant. Jemperli can harm your unborn baby.\nFemales who are able to become pregnant:\nYour healthcare provider will do a pregnancy test before you start treatment.\nYou should use effective birth control during treatment and for 4 months after your last dose. Talk to your healthcare provider about birth control methods that you can use during this time.\nTell your healthcare provider right away if you think you may be pregnant or if you become pregnant during treatment.\nare breastfeeding or plan to breastfeed. It is not known if Jemperli passes into your breast milk.\nDo not breastfeed during treatment and for 4 months after your last dose.\nTell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.\nKnow the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.\nHow will I receive Jemperli?\nYour healthcare provider will give you Jemperli into your vein through an intravenous (IV) line over 30 minutes.\nJemperli is usually given every 3 weeks for the first 4 doses, and then beginning 3 weeks later, it is usually given every 6 weeks.\nYour healthcare provider will decide how many treatments you need.\nYour healthcare provider will do blood tests to check you for side effects.\nIf you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment.\n',NULL),(431,'jentadueto','Usual Adult Dose for Diabetes Type 2:\nLinagliptin-metformin immediate release tablets:\n-Initial dose for patients currently not receiving metformin: linagliptin 2.5 mg/metformin 500 mg orally twice a day\n-Initial dose for patients currently receiving metformin: linagliptin 2.5 mg in combination with one-half of current metformin dose orally twice a day\n-Initial dose for patients currently receiving linagliptin and metformin as individual components: switch to combination product containing the same doses of each component orally twice a day\nMaintenance dose: Individualize dose based on safety and efficacy\nMaximum dose: linagliptin 5 mg/day; metformin 2000 mg/day\nLinagliptin-metformin extended-release tablets:\n-Initial dose for patients currently not receiving metformin: linagliptin 5 mg/metformin extended-release 1000 mg orally once a day\n-Initial dose for patients currently receiving metformin: linagliptin 5 mg in combination with a similar total daily dose of metformin orally once a day\n-Initial dose for patients currently receiving linagliptin and metformin as individual components: switch to combination product containing similar doses of each component orally once a day\nMaintenance dose: Individualize dose based on safety and efficacy\nMaximum dose: linagliptin 5 mg/day; metformin 2000 mg/day\nComments:\n-Patients taking two linagliptin 2.5 mg/metformin 1000 mg extended-release tablets should take the 2 tablets together once a day.\n-When used in combination with insulin or an insulin secretagogue, a lower dose of insulin or the insulin secretagogue may be necessary to reduce the risk of hypoglycemia.\nUse: To improve glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise when treatment with both linagliptin and metformin are appropriate.\n Detailed Jentadueto dosage information\nWhat happens if I miss a dose?\nTake the medicine (with food) as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure).\n','Many drugs can interact with linagliptin and metformin, making this medicine less effective or increasing your risk of lactic acidosis. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Jentadueto drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Jentadueto: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nStop taking this medicine and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.\nMild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, fast/slow or irregular heartbeats, dizziness, feeling cold, or feeling very weak or tired.\nCall your doctor at once if you have:\na severe autoimmune reaction - itching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints; or\nsymptoms of heart failure - shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nCommon Jentadueto side effects include:\nsore throat;\nsinus pain, stuffy nose; or\ndiarrhea.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jentadueto side effects (more detail)\n','Jentadueto contains a combination of linagliptin and metformin. Linagliptin and metformin are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Linagliptin works by regulating the levels of insulin your body produces after eating.\nJentadueto is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.\nJentadueto is not for treating type 1 diabetes.\n','You should not use Jentadueto if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).\nThere may be an increased risk of developing lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.\nBefore you take Jentadueto, tell your doctor if you have liver disease, a serious infection, heart disease, a history of pancreatitis, if you have recently had a heart attack, or if you are over 65 years old and have not recently had your kidney function checked.\nIf you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Jentadueto.\nYou may develop lactic acidosis. Get emergency medical help if you have unusual muscle pain, trouble breathing, irregular heartbeats, dizziness, vomiting, or if you feel cold, tired, or very weak.\nBefore taking this medicine\nYou should not use Jentadueto if you are allergic to linagliptin (Tradjenta) or metformin, or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).\nTo make sure Jentadueto is safe for you, tell your doctor if you have ever had:\nkidney disease;\nheart disease;\nliver disease;\npancreatitis;\ngallstones;\nalcoholism; or\nhigh triglycerides (a type of fat in the blood).\nYou may develop lactic acidosis. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.\nIf you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Jentadueto. Be sure your caregivers know ahead of time that you are using this medication.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using Jentadueto if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nJentadueto may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.\nJentadueto is not approved for use by anyone younger than 18 years old.\nHow should I take Jentadueto?\nTake Jentadueto exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nTake Jentadueto with a meal, unless your doctor tells you otherwise.\nSwallow the tablet whole and do not crush, chew, or break it.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nJentadueto is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture and heat.\n','Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.\n'),(432,'jentadueto-xr','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake Jentadueto XR with a meal, unless your doctor tells you otherwise.\nSwallow the tablet whole and do not crush, chew, or break it.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nJentadueto XR is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture and heat.\n Detailed Jentadueto XR dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the medicine (with food) as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure).\n','Many drugs can affect Jentadueto XR, making this medicine less effective or increasing your risk of lactic acidosis. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Jentadueto XR drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nStop taking  Jentadueto XR and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.\nMild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, fast/slow or irregular heartbeats, dizziness, feeling cold, or feeling very weak or tired.\nCall your doctor at once if you have:\na severe autoimmune reaction--itching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints; or\nsymptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nCommon side effects may include:\nsore throat;\nsinus pain, stuffy nose; or\ndiarrhea.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jentadueto XR side effects (more detail)\n','Jentadueto XR are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Linagliptin works by regulating the levels of insulin your body produces after eating.\nJentadueto XR is a combination medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.  Jentadueto XR is not for treating type 1 diabetes.\nJentadueto XR may also be used for purposes not listed in this medication guide.\n','You should not use this medicine if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).\nYou may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Get emergency medical help if you have unusual muscle pain, trouble breathing, irregular heartbeats, dizziness, vomiting, or if you feel cold, tired, or very weak.\nBefore taking this medicine\nYou should not use  Jentadueto XR if you are allergic to linagliptin (Tradjenta) or metformin, or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin).\nTell your doctor if you have ever had:\nkidney disease;\nheart disease;\nliver disease;\npancreatitis;\ngallstones;\nalcoholism; or\nhigh triglycerides (a type of fat in the blood).\nYou may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.\nIf you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Jentadueto XR. Be sure your caregivers know ahead of time that you are using this medication.\nTell your doctor if you are pregnant or breastfeeding.\nFollow your doctor\'s instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nThis medicine may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.\nThis medicine is not approved for use by anyone younger than 18 years old.\n','Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.\n'),(433,'jevtana','Usual Adult Dose for Prostate Cancer:\n25 mg/m2 IV over 1 hour every three weeks\nComments:\n-Use in combination with prednisone or prednisolone.\n-Give premedication regimen at least 30 minutes prior to each administration.\n-Give antiemetics prophylactically or as needed.\n-Ensure adequate hydration throughout treatment.\nUse: Use in combination with prednisone or prednisolone for the treatment of patients with hormone refractory metastatic prostate cancer previously treated with a docetaxel containing regimen.\n Detailed Jevtana dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Jevtana injection.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe vomiting or diarrhea, fever, or worsening flu-like symptoms.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may interact with cabazitaxel, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Jevtana drug interactions (more detail)\n','Jevtana can cause a serious allergic reaction. Get emergency medical help if you have signs of an allergic reaction to Jevtana: hives, rash or skin redness; chest tightness or trouble breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.\nJevtana can cause serious or fatal side effects. Call your doctor at once if you have:\nnumbness, burning pain, or tingly feeling in your hands or feet;\nsudden chest pain or discomfort, wheezing, dry cough, feeling short of breath;\nstomach pain or tenderness, severe vomiting or diarrhea, ongoing constipation;\nblood in your urine, urinating more often, pain or burning when you urinate;\nlow blood cell counts - fever, chills, muscle pain, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or\nsigns of a kidney problem - little or no urinating; painful or difficult urination; swelling in your hands or feet; feeling tired or short of breath.\nYour cancer treatments may be delayed or permanently discontinued if you have certain side effects.\nSome side effects may be more likely in older adults.\nCommon Jevtana side effects may include:\nfever, low blood cell counts;\nnumbness or tingling;\nnausea, vomiting, stomach pain, loss of appetite;\nconstipation, diarrhea;\nweakness, tired feeling;\nblood in your urine;\nback pain, joint pain;\ncough, shortness of breath;\naltered sense of taste; or\nhair loss.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jevtana side effects (more detail)\n','Jevtana (cabazitaxel) is a prescription cancer medicine that interferes with the growth and spread of cancer cells in the body.\nJevtana is used together with prednisone to treat prostate cancer that is resistant to medical or surgical treatments that lower testosterone and has spread to other parts of the body (metastatic).\nJevtana is usually given when the prostate cancer has worsened (progressed) after being previously treated with other medicines that included docetaxel as part of the treatment.\n','You should not use Jevtana if you have severe liver disease, low white blood cell counts, or an allergy to any medicine that contains polysorbate 80.\nJevtana affects your immune system. You may get infections more easily, even serious or fatal infections, especially if you are 65 or older. Call your doctor if you have a fever, muscle pain, cough, diarrhea, or pain or burning when you urinate.\nCall your doctor right away if you have symptoms such as: fever, cough, body aches, easy bruising or bleeding, burning when you urinate, decreased urination, swelling in your hands or feet, severe stomach pain, constipation, blood in your urine or stools, or sudden chest pain and shortness of breath.\nA serious allergic reaction may occur during the injection. Tell your caregivers right away if you have a rash or skin redness, chest tightness or trouble breathing, or if you feel like you might pass out.\nBefore taking this medicine\nYou should not use Jevtana if you are allergic to cabazitaxel, or if you have:\nsevere liver disease;\nlow white blood cell counts; or\nan allergy to any medicine that contains polysorbate 80.\nTo make sure Jevtana is safe for you, tell your doctor if you have ever had:\nradiation treatment;\nliver or kidney disease;\nbreathing problems; or\na severe allergic reaction to any medication.\nAlthough not for use by women, cabazitaxel can cause birth defects in a baby if the father is using this medicine.\nUse effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor at once if a pregnancy occurs during this time.\nThis medicine may affect fertility (your ability to have children). However, it is important to use birth control to prevent pregnancy because cabazitaxel can harm an unborn baby.\nHow is Jevtana given?\nJevtana is given as an infusion into a vein. A healthcare provider will give you this injection.\nThis medicine must be given slowly, and the infusion can take about 1 hour to complete.\nJevtana is usually given once every 3 weeks. You will be given other medications to prevent certain side effects.\nYou will most likely take prednisone (a steroid medicine) by mouth every day throughout your Jevtana treatment. Do not stop taking prednisone without your doctor\'s advice, or you could have unpleasant side effects caused by Jevtana. Tell your doctor if you miss any doses or you stop taking prednisone for any reason.\nJevtana affects your immune system. You may get infections more easily, even serious or fatal infections, especially if you are 65 or older. Your doctor will need to examine you on a regular basis.\nCall your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while receiving Jevtana, which can lead to a serious electrolyte imbalance.\nYour doctor may tell you to check your temperature at home throughout your treatment with Jevtana.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(434,'jolessa','This section provides information on the proper use of a number of products that contain levonorgestrel and ethinyl estradiol.  It may not be specific to Jolessa. Please read with care.\nIt is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.\nThis medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.\nWhen you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented. Use a second form of birth control, such as a condom, spermicide, or diaphragm, for the first 7 days of your first cycle of pills.\nTake this medicine at the same time each day. Birth control pills work best when no more than 24 hours pass between doses.\nDo not skip or delay taking your pill by more than 24 hours. If you miss a dose, you could get pregnant. Ask your doctor for ways to help you remember to take your pills or about using another method of birth control.\nYou may feel sick or nauseated, especially during the first few months that you take this medicine. If your nausea is continuous and does not go away, call your doctor.\nUse another form of birth control if you vomit or have diarrhea after taking the pills until you check with your doctor.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nYour doctor may ask you to begin your dose on the first day of your menstrual period (called Day 1 start) or on the first Sunday after your menstrual period starts (called Sunday start). When you begin on a certain day it is important that you follow that schedule, even if you miss a dose. Do not change your schedule on your own. If the schedule that you use is not convenient, talk with your doctor about changing it. For a Sunday start, you need to use another form of birth control (eg, condom, diaphragm, spermicide) for the first 7 days.\nFor oral dosage form (tablets):\nFor contraception (to prevent pregnancy):\nChateal®:\nAdults—One white to off-white tablet (active) taken at the same time each day for 21 consecutive days followed by one green (inert) tablet daily for 7 days per menstrual cycle.\nChildren—Use and dose must be determined by your doctor.\nTriphasil®-28:\nAdults—One brown, white, light-yellow (in order) (active) tablet taken at the same time each day for 21 consecutive days followed by one light-green (inert) tablet daily for 7 days per menstrual cycle.\nChildren—Use and dose must be determined by your doctor.\nMissed dose\nCall your doctor or pharmacist for instructions.\nThis medicine has specific patient instructions on what to do if you miss a dose. Read and follow these instructions carefully and call your doctor if you have any questions.\nIf you miss one active pill: Take it as soon as you can, then take your next pill at your regular schedule. This means you may take 2 pills in 1 day.\nIf you miss two active pills in week 1 or 2: Take two pills as soon as you can and two more pills the next day. Continue taking one pill a day until you finish the pack. Use a second form of birth control (eg, condom, spermicide) for 7 days after you miss a dose.\nIf you miss two active pills in week 3, or you miss three or more active pills in a row in weeks 1, 2, or 3:\nDay 1 start: Throw out the rest of the pack and start a new pack that same day. Use a second form of birth control (eg, condom, spermicide) for 7 days after you miss a dose.\nSunday start: Continue taking one pill a day until Sunday, then throw out the rest of the pack and start a new pack that same day. Use a second form of birth control (eg, condom, spermicide) for 7 days after you miss a dose, to prevent pregnancy.\nYou could have light bleeding or spotting if you do not take a pill on time. The more pills you miss, the more likely you are to have bleeding.\nMake sure your doctor knows if you miss your period 2 months in a row, because this could mean that you are pregnant.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Jolessa dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nIncidence not known\nAbsent, missed, or irregular menstrual periods\nanxiety\nbloody stools\nblurred vision\nbreast tenderness, enlargement, discharge\nchanges in skin color, pain, tenderness, or swelling of the foot or leg\nchest pain or discomfort\nchills\nclay-colored stools\nconfusion\ncough\ndark or cloudy urine\ndecrease in urine output or decrease in urine-concentrating ability\ndiarrhea\ndifficult, burning, or painful urination\ndifficulty in speaking\ndizziness or lightheadedness\ndouble vision\ndull ache or feeling of pressure or heaviness in the legs\nfainting\nfast heartbeat\nfever\nfluid-filled skin blisters\nfrequent urge to urinate\nheadache, severe and throbbing\ninability to move the arms, legs, or facial muscles\ninability to speak\nitching of the vagina or outside the genitals\nitching skin near damaged veins\nlight vaginal bleeding between regular menstrual periods\nloss of appetite\nnausea\nnervousness\npain during sexual intercourse\npain or discomfort in the arms, jaw, back or neck\npelvic pain\npounding in the ears\nsensitivity to the sun\nskin thinness\nslow or fast heartbeat\nslow speech\nstomach bloating and cramping\nstomach pain and tenderness\nstopping of menstrual bleeding\nsweating\nswelling, pain, or tenderness in the upper abdominal area\nswollen feet and ankles\ntenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area\nthick, white curd-like vaginal discharge without odor or with mild odor\ntroubled breathing\ntwitching, uncontrolled movements of the tongue, lips, face, arms, or legs\nunpleasant breath odor\nunusual tiredness or weakness\nvomiting\nvomiting of blood\nyellow eyes or skin\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nIncidence not known\nAcne\nchanges in appetite\nchanges in weight\ndecreased interest in sexual intercourse\ndecreased milk production\nloss in sexual ability, desire, drive, or performance\nmental depression\npatchy brown or dark brown discoloration of the skin\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Jolessa side effects (more detail)\n','Levonorgestrel and ethinyl estradiol combination is used to prevent pregnancy. It works by stopping a woman\'s egg from fully developing each month. The egg can no longer accept a sperm and fertilization (pregnancy) is prevented.\nNo contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.\nThis medicine will not prevent HIV infection or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.\nThis medicine is available only with your doctor\'s prescription.\n','It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may also be needed to check for unwanted effects. Your doctor may also want to check your blood pressure while taking this medicine.\nAlthough you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away. Make sure your doctor knows if you had given birth within 4 weeks before you start using this medicine.\nIf you suspect that you may be pregnant, check with your doctor right away.\nDo not use this medicine together with medicine to treat hepatitis C virus infection, including ombitasvir/paritaprevir/ritonavir, with or without dasabuvir (Technivie®, Viekira Pak®).\nYou might have some light bleeding or spotting when you first start using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than a few days in a row, call your doctor.\nDo not use this medicine if you smoke cigarettes or if you are over 35 years of age. If you smoke while using ethinyl estradiol and norgestrel combination, you increase your risk of having a blood clot, heart attack, or stroke. Your risk is even higher if you are over age 35, if you have diabetes, high blood pressure, high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. Keep your diabetes under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.\nUsing this medicine may increase your risk of having blood clotting problems. Check with your doctor right away if you have pain in the chest, groin, or legs, especially the calves, difficulty with breathing, a sudden, severe headache, slurred speech, a sudden, a sudden loss of coordination, or vision changes while using this medicine.\nUsing this medicine may increase your risk of having cancer of the breast or your reproductive organs (eg, endometrium, ovaries, cervix). Talk with your doctor about this risk. Check with your doctor right away if you experience abnormal vaginal bleeding.\nCheck with your doctor right away if you have pain or tenderness in the stomach, dark urine, pale stools, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.\nCheck with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want an eye doctor (ophthalmologist) to check your eyes.\nThis medicine may increase your risk of having gallbladder disease. Check with your doctor if you start to have stomach pains, nausea, and vomiting.\nMake sure any doctor or dentist who treats you knows that you are using this medicine. The results of some medical tests may be affected by this medicine.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John\'s wort) or vitamin supplements.\n',NULL),(435,'jolivette','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nCarefully follow your doctor\'s dosing instructions about when to start taking Jolivette for contraception if you are switching from a combination birth control pill (estrogen and progestin).\nIf you take Jolivette for contraception: Take one pill every day, no more than 24 hours apart. You may get pregnant if you do not take one pill daily.\nYou may need to use back-up birth control (such as condoms with spermicide) if you are sick with vomiting or diarrhea, or if you are 3 or more hours late in taking your daily dose.\nIf you take Jolivette for menstrual disorders or abnormal vaginal bleeding: You will most likely take the medicine for only 5 to 10 days. Vaginal bleeding will occur 3 to 7 days after your last dose.\nIf you take Jolivette for endometriosis: This medicine is usually taken daily long-term for several months. Your doctor may occasionally change your dose.\nYour doctor should check your progress on a regular basis. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms.\nReport any unusual vaginal bleeding right away.\nJolivette can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine.\nStore this medication at room temperature away from moisture, heat, and light.\n Detailed Jolivette dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nCall your doctor for instructions, or follow the patient instructions provided with your medicine.\nMissing a birth control pill increases your risk of becoming pregnant. If you are more than 3 hours late for your dose, take the medicine as soon as you remember and use back-up birth control for at least 48 hours. Take your next pill at the regularly scheduled time and continue on your regular dosing schedule.\nIf you miss a period for two months in a row, call your doctor because you might be pregnant.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nAn overdose of  Jolivette is not expected to be dangerous.\n','Some drugs can make Jolivette less effective, which may result in unintended pregnancy if you use  Jolivette for contraception. Tell your doctor about all your other medicines, especially:\nSt. John\'s wort;\nmedicine to treat an infection (antibiotics or antifungal medicine);\nmedicine to treat tuberculosis;\nmedicine to treat HIV or AIDS; or\nseizure medication.\nThis list is not complete. Other drugs may affect Jolivette, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Jolivette drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsudden vision loss, bulging eyes, or severe headache;\nswelling, rapid weight gain;\nunusual vaginal bleeding;\nmissed menstrual periods;\npelvic pain (especially on one side);\na breast lump;\na light-headed feeling, like you might pass out;\nincreased thirst, increased urination;\nliver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes); or\nsigns of a blood clot--sudden numbness or weakness, problems with vision or speech, chest pain, shortness of breath, swelling or redness in an arm or leg.\nCommon side effects may include:\nirregular vaginal bleeding or spotting;\nheadache;\nbreast pain or swelling;\nstomach pain, bloating, nausea, vomiting;\nhair loss;\ndepressed mood, trouble sleeping;\nweight gain; or\nvaginal itching or discharge.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jolivette side effects (more detail)\n','Jolivette is a form of progesterone, a female hormone important for regulating ovulation and menstruation.\nJolivette is used for birth control (contraception) to prevent pregnancy.\nJolivette is also used to treat menstrual disorders, endometriosis, or abnormal vaginal bleeding caused by a hormone imbalance.\nNot all brands of  Jolivette are for the same uses. Some brands are for use only as contraception. Others are for use in treating endometriosis or vaginal bleeding disorders. Avoid medication errors by using only the brand, form, and strength your doctor prescribes.\nJolivette may also be used for other purposes not listed in this medication guide.\n','You should not use this medicine if you you have: undiagnosed vaginal bleeding, breast cancer, liver disease, or a liver tumor. You may not be able to take Jolivette if you have ever had a heart attack, a stroke, or blood clot.\nDo not use if you are pregnant or trying to become pregnant.\nIn some cases, you should not take Jolivette if you are nursing.\nBefore taking this medicine\nYou should not use Jolivette if you are allergic to it, or if you have:\nunusual vaginal bleeding that has not been checked by a doctor;\nliver disease or a liver tumor;\nbreast cancer; or\na history of blood clots in your brain, eyes, lungs, or legs.\nDo not use Jolivette if you are pregnant or trying to become pregnant. Stop taking the medicine and tell your doctor right away if you become pregnant.\nAsk your doctor about using  Jolivette while you are breast-feeding. In some cases, you should not take Jolivette if you are nursing.\nTell your doctor if you have ever had:\nheart disease, high blood pressure;\nliver disease;\ndepression;\nmigraine headaches;\ndiabetes;\nhigh cholesterol or triglycerides;\nuterine fibroid tumors;\nepilepsy;\nkidney disease;\nasthma; or\nif you smoke.\nDo not give this medicine to a child without medical advice.\n','Do not use estrogen medication unless your doctor tells you to.\nAvoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while taking Jolivette for contraception.\nJolivette will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.\n'),(436,'jornay-pm','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYour dose needs may change if you switch to a different brand, strength, or form of  Jornay PM. Avoid medication errors by using only the medicine your doctor prescribes.\nJornay PM may be habit-forming. Misuse can cause addiction, overdose, or death. Never share this medicine with another person. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.\nTake this medicine in the evening.\nFollow the directions on your medicine label about taking Jornay PM with or without food.\nSwallow the extended-release capsule or tablet whole and do not crush, chew, or break it.\nIf you cannot swallow a capsule whole, open it and mix the medicine with pudding or applesauce. Swallow the mixture right away without chewing.\nThe chewable tablet must be chewed before you swallow it.\nMeasure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).\nAllow the orally disintegrating tablet to dissolve in your mouth without chewing.\nTell your doctor if you have a planned surgery.\nYour doctor will need to check your progress on a regular basis. Tell any doctor who treats you that you are using this medicine.\nStore at room temperature away from moisture and heat.\nKeep your medicine in a place where no one can use it improperly.\n Detailed Jornay PM dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is later than 6:00 p.m. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of  Jornay PM could be fatal.\n','Other drugs may affect Jornay PM, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Jornay PM drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsigns of heart problems--chest pain, trouble breathing, feeling like you might pass out;\nsigns of psychosis--hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;\nsigns of circulation problems--numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes; or\npenis erection that is painful or lasts 4 hours or longer (rare).\nJornay PM can affect growth in children. Tell your doctor if your child is not growing at a normal rate.\nCommon side effects may include:\nexcessive sweating;\nmood changes, feeling nervous or irritable, sleep problems (insomnia);\nfast heart rate, pounding heartbeats or fluttering in your chest, increased blood pressure;\nloss of appetite, weight loss;\ndry mouth, nausea, stomach pain; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jornay PM side effects (more detail)\n','Jornay PM is a stimulant medicine used to treat attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), and narcolepsy.\nJornay PM may also be used for purposes not listed in this medication guide.\n','Jornay PM may be habit-forming. Misuse can cause addiction, overdose, or death.\nStimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.\nYou may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.\nJornay PM may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.\nCall your doctor right away if you have: signs of heart problems--chest pain, feeling light-headed or short of breath; signs of psychosis--paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems--unexplained wounds on your fingers or toes.\nBefore taking this medicine\nDo not use Jornay PM if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.\nYou may not be able to use Jornay PM if you are allergic to it, or if you have:\nglaucoma;\na personal or family history of tics (muscle twitches) or Tourette\'s syndrome; or\nsevere anxiety, tension, or agitation (stimulant medicine can make these symptoms worse).\nStimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have:\nheart problems or a congenital heart defect;\nhigh blood pressure; or\na family history of heart disease or sudden death.\nTell your doctor if you or anyone in your family has ever had:\ndepression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions;\nmotor tics (muscle twitches) or Tourette\'s syndrome;\nblood circulation problems in the hands or feet;\nseizures or epilepsy;\nproblems with the esophagus, stomach, or intestines;\nan abnormal brain wave test (EEG); or\ndrug or alcohol addiction.\nTell your doctor if you are pregnant or breastfeeding.\nNot approved for use by anyone younger than 6 years old.\n','Avoid drinking alcohol.\nAvoid driving or hazardous activity until you know how  Jornay PM will affect you. Your reactions could be impaired.\n'),(437,'jublia','Usual Adult Dose for Onychomycosis -- Toenail:\nApply to affected toenail(s) once a day for 48 weeks.\nComments:\n-The integrated flow-through brush applicator should be used.\n-The toenail, toenail folds, toenail bed, hyponychium, and undersurface of the toenail plate should be completely covered.\nUse: For the topical treatment of onychomycosis of the toenail(s) due to Trichophyton rubrum and T mentagrophytes\nUsual Pediatric Dose for Onychomycosis -- Toenail:\n6 years or older: Apply to affected toenail(s) once a day for 48 weeks.\nComments:\n-The integrated flow-through brush applicator should be used.\n-The toenail, toenail folds, toenail bed, hyponychium, and undersurface of the toenail plate should be completely covered.\nUse: For the topical treatment of onychomycosis of the toenail(s) due to T rubrum and T mentagrophytes\n Detailed Jublia dosage information\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nAn overdose of Jublia solution is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\n','Medicine used on the nail is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n','Get emergency medical help if you have signs of an allergic reaction to Jublia: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere redness, itching, or swelling of the affected toenail.\nCommon Jublia side effects may include:\npain, redness, swelling, burning, stinging, itching, or blisters where the medicine was applied; or\ningrown toenail.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jublia side effects (more detail)\n','Jublia topical solution contains efinaconazole, an antifungal medication that fights infections caused by fungus.\nJublia solution is used to treat a fungal infection of the toenail called onychomycosis.\nJublia solution is a clear, colorless to pale yellow solution supplied in a white plastic bottle with a flow-through brush applicator.\n','Jublia solution is for external use only and is not for ophthalmic, oral, or intravaginal use. It is for use on toenails and immediately adjacent skin only.\nAvoid pedicures, the use of nail polish, and cosmetic nail products while using Jublia.\nFollow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use Jublia if you are allergic to efinaconazole.\nIt is not known whether efinaconazole will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.\nIt is not known whether efinaconazole topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breastfeeding a baby.\nJublia solution is not approved for use by anyone younger than 6 years old.\nHow should I use Jublia solution?\nUse Jublia solution exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nJublia is usually applied to affected toenails once daily for 48 weeks (approximately 11 months).\nBefore you apply this medicine, wash and thoroughly dry your toenails. Wait at least 10 minutes after showering, bathing, or washing the area before applying Jublia.\nApply this medicine over the entire toenail and under the tip of the nail. Allow the medicine to dry completely before putting on a sock or shoe.\nAfter you apply Jublia solution, wait at least 10 minutes before you take a bath or shower.\nAvoid getting this medicine on any other skin besides the cuticles or the skin around your toenail.\nCall your doctor if your symptoms do not improve, or if they get worse while using Jublia.\nUse this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses can increase your risk of infection that is resistant to medication.\nStore in an upright position at room temperature, away from moisture and heat. Do not freeze.\nStore in an upright position at room temperature, away from moisture and heat. Keep the bottle tightly closed when not in use. Do not freeze.\nJublia solution is flammable. Do not use near high heat or open flame. Do not smoke until the solution has completely dried on your nail.\n','Do not get this medicine in your eyes, mouth, or vagina. Jublia solution is for use only on the toenails.\nAvoid having a pedicure or using nail polish on your toenails.\n'),(438,'juluca','Usual Adult Dose of Juluca for HIV Infection:\n1 tablet orally once a day with a meal\nUse: As a complete regimen for the treatment of HIV-1 infection to replace a stable antiretroviral regimen in patients who are virologically-suppressed (HIV-1 RNA less than 50 copies/mL) for at least 6 months with no history of treatment failure and no known substitutions associated with resistance to the individual components\n Detailed Juluca dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Some medicines can make Juluca less effective when taken at the same time. If you take any of the following medicines, take your dose at least 4 hours before or 6 hours after you take the other medicine.\nantacids or laxatives that contain calcium, magnesium, or aluminum (such as Maalox, Milk of Magnesia, Mylanta, Rolaids, Tums, and others), or the ulcer medicine sucralfate (Carafate);\nbuffered medicine; or\nvitamin or mineral supplements that contain calcium or iron (but if you take dolutegravir and rilpivirine with food, you can take these supplements at the same time).\nMany drugs can interact with dolutegravir and rilpivirine, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Juluca drug interactions (more detail)\n','Stop taking this medicine and get emergency medical help if you have signs of an allergic reaction to Juluca: fever, general ill feeling, trouble breathing, extreme tiredness; mouth sores, redness or swelling in your eyes; blistering or peeling skin; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nthoughts about suicide or hurting yourself;\nanxiety, sadness, feeling hopeless; or\nliver problems - nausea, vomiting, loss of appetite, right-sided upper stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nDolutegravir and rilpivirine affects your immune system, which may cause certain side effects (even weeks or months after you\'ve taken this medicine). Tell your doctor if you have:\nsigns of a new infection - fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;\ntrouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or\nswelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.\nCommon Juluca side effects may include:\nheadache; or\ndiarrhea.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Juluca side effects (more detail)\n','Juluca contains a combination of dolutegravir and rilpivirine. Dolutegravir and rilpivirine are antiviral medicines that prevents human immunodeficiency virus (HIV) from multiplying in your body.\nJuluca is used to treat HIV, the virus that can cause the acquired immunodeficiency syndrome (AIDS).\nJuluca is not a cure for HIV or AIDS.\nJuluca is for use only in people who have been successfully treated with other antiviral medications for at least 6 months.\n','Taking Juluca during the first trimester of pregnancy may cause birth defects. Use effective birth control to prevent pregnancy while you are using dolutegravir.\nBefore taking this medicine\nYou should not use Juluca if you are allergic to dolutegravir or rilpivirine.\nSome medicines can cause unwanted or dangerous effects when used with Juluca. Your doctor may need to change your treatment plan if you also use:\ndofetilide (can cause serious medical problems or death when taken with Juluca);\nSt John\'s wort;\nmore than one dose of dexamethasone;\ncarbamazepine, oxcarbazepine, phenobarbital, phenytoin;\nrifampin, rifapentine; or\nesomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole.\nTo make sure Juluca is safe for you, tell your doctor if you have ever had:\nliver problems;\nmental illness;\na severe skin rash or allergic reaction to dolutegravir or rilpivirine; or\nif you also take rifabutin.\nYou may need to have a negative pregnancy test before starting this treatment.\nJuluca may harm an unborn baby if you take the medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.\nHIV can be passed to your baby if the virus is not controlled during pregnancy. If you are pregnant, your name may be listed on a registry to track any effects of antiviral medicine on the baby. Use your medications properly to control HIV.\nWomen with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.\nHow should I take Juluca?\nTake Juluca exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nAlways take this medicine with food, not with a meal replacement drink.\nYou will need frequent blood tests.\nDo not change your doses or medication schedule without your doctor\'s advice. Every person with HIV or AIDS should remain under the care of a doctor.\nGet your prescription refilled before you run out of medicine completely.\nStore at room temperature away from moisture and heat. Keep the tablets in their original container, along with any packet or canister of moisture-absorbing preservative.\n','This medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.\n'),(439,'junel-1-20','This section provides information on the proper use of a number of products that contain ethinyl estradiol and norethindrone.  It may not be specific to Junel 1/20. Please read with care.\nIt is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.\nTo make using oral contraceptives as safe and reliable as possible, you should understand how and when to take them and what effects may be expected.\nThis medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.\nThis medicine is available in blister packs with a Dialpak® tablet dispenser. Each blister pack contains 28 tablets with different colors that need to be taken in the same order as directed on the blister pack.\nWhen you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented. Use a second form of contraception, such as a condom, spermicide, or diaphragm, for the first 7 days of your first cycle of pills.\nTake this medicine at the same time each day (with meals or at bedtime). Birth control pills work best when no more than 24 hours pass between doses.\nDo not skip or delay taking your pill by more than 24 hours. If you miss a dose, you could get pregnant. Ask your doctor for ways to help you remember to take your pills or about using another method of birth control.\nYou may feel sick or nauseated, especially during the first few months that you take this medicine. If your nausea is continuous and does not go away, call your doctor.\nDo not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nYour doctor may ask you to begin your dose on the first day of your menstrual period (called Day 1 start) or on the first Sunday after your menstrual period starts (called Sunday start). When you begin on a certain day it is important that you follow that schedule, even if you miss a dose. Do not change your schedule on your own. If the schedule that you use is not convenient, check with your doctor about changing it. For a Sunday start, you need to use another form of birth control (eg, condom, diaphragm, spermicide) for the first 7 days.\nYou should begin your next and all subsequent 28-day regimens of therapy on the same day of the week as the first regimen began and follow the same schedule.\nFor oral dosage form (tablets):\nFor contraception (to prevent pregnancy):\nAdults and teenagers—\nLoestrin® 21: One white or green tablet (active) taken at the same time each day for 21 consecutive days followed by one week without the tablets.\nLoestrin® Fe: One white or green tablet (active) taken at the same time each day for 21 consecutive days followed by one brown (inert) tablet daily for 7 days per menstrual cycle.\nModicon®: One white tablet (active) taken at the same time each day for 21 consecutive days followed by one green (inert) tablet daily for 7 days per menstrual cycle.\nOrtho-novum®: One white or peach tablet (active) taken at the same time each day for 21 consecutive days followed by one green (inert) tablet daily for 7 days per menstrual cycle.\nChildren—Use and dose must be determined by your doctor.\nMissed dose\nCall your doctor or pharmacist for instructions.\nThis medicine has specific patient instructions on what to do if you miss a dose. Read and follow these instructions carefully and call your doctor if you have any questions.\nIf you miss one active pill: Take it as soon as you can, then take your next pill at your regular schedule.\nIf you miss two active pills in week 1 or 2: Take two pills as soon as you can and two more pills the next day. Continue taking one pill a day until you finish the pack. Use a second form of birth control (eg, condom, spermicide) for 7 days after you miss a dose.\nIf you miss two active pills in week 3, or you miss three or more active pills in a row in weeks 1, 2, or 3:\nDay 1 start: Throw out the rest of the pack and start a new pack that same day. Use a second form of birth control (eg, condom, spermicide) for 7 days after you miss a dose.\nSunday start: Continue taking one pill a day until Sunday, then throw out the rest of the pack and start a new pack that same day. Use a second form of birth control (eg, condom, spermicide) for 7 days after you miss a dose, to prevent pregnancy.\nYou may not have a period for that month if you miss more than one dose or change your schedule.\nYou could have light bleeding or spotting if you do not take a pill on time. The more pills you miss, the more likely you are to have bleeding.\nMake sure your doctor knows if you miss your period 2 months in a row, because this could mean that you are pregnant.\nStorage\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Junel 1/20 dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nIncidence not known\nAbsent, missed, or irregular menstrual periods\nanxiety\nchange in vision\nchanges in skin color\nchest pain or discomfort\nchills\nclay-colored stools\nconstipation\ncough\ndark urine\ndiarrhea\ndizziness or lightheadedness\nfainting\nfast heartbeat\nfever\nheadache\nhives or welts\nitching skin\nlarge, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs\nloss of appetite\nmedium to heavy, irregular vaginal bleeding between regular monthly periods, which may require the use of a pad or a tampon\nnausea\npain or discomfort in the arms, jaw, back, or neck\npain, tenderness, or swelling of the foot or leg\npains in the chest, groin, or legs, especially in the calves of the legs\npounding in the ears\nrash\nredness of the skin\nsevere headaches of sudden onset\nslow or fast heartbeat\nstomach pain\nsudden loss of coordination or slurred speech\nsweating\ntroubled breathing\nunusual tiredness or weakness\nvomiting\nvomiting of blood\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nIncidence not known\nBloating\nblotchy spots on the exposed skin\nbreast enlargement or tenderness\ndiscouragement\nfeeling sad or empty\nirritability\nitching of the vagina or outside genitals\nloss of interest or pleasure\npain during sexual intercourse\nstomach cramps\nthick, white curd-like vaginal discharge without odor or with mild odor\ntiredness\ntrouble concentrating\ntrouble sleeping\ntrouble wearing contact lenses\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Junel 1/20 side effects (more detail)\n','Ethinyl estradiol and norethindrone combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and norethindrone, and when taken properly, prevents pregnancy. It works by stopping a woman\'s egg from fully developing each month. The egg can no longer accept a sperm and fertilization (pregnancy) is prevented.\nNo contraceptive method is 100 percent effective. Birth control methods, such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.\nThis medicine does not prevent HIV infection or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.\nThis medicine is available only with your doctor\'s prescription.\n','It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and does not cause unwanted effects. These visits will usually be every 6 to 12 months, but some doctors require them more often. Your doctor may also want to check your blood pressure while taking this medicine.\nAlthough you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away. Make sure your doctor knows if you had given birth within 4 weeks before you start using this medicine.\nDo not use this medicine together with medicine to treat hepatitis C virus infection, including ombitasvir/paritaprevir/ritonavir, with or without dasabuvir (Technivie®, Viekira Pak®).\nVaginal bleeding of various amounts may occur between your regular menstrual periods during the first 3 months of use. This is sometimes called spotting when slight, or breakthrough bleeding when heavier.\nIf this should occur, continue with your regular dosing schedule.\nThe bleeding usually stops within 1 week. Check with your doctor if the bleeding continues for more than 1 week.\nIf the bleeding continues after you have been taking hormonal contraceptives on schedule and for more than 3 months, check with your doctor.\nCheck with your doctor right away if you missed a menstrual period. Missed periods may occur if you skip one or more tablets and have not taken your pills exactly as directed. If you miss two periods in a row, call your doctor for a pregnancy test before you take any more pills.\nIf you suspect that you may be pregnant, check with your doctor right away.\nDo not use this medicine if you smoke cigarettes or if you are over 35 years of age. If you smoke while using norethindrone and ethinyl estradiol combination, you increase your risk of having a blood clot, heart attack, or stroke. Your risk is even higher if you are over age 35, if you have diabetes, high blood pressure, high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. Keep your diabetes under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.\nUsing this medicine may increase your risk of having blood clotting problems. Check with your doctor right away if you have pain in the chest, groin, or legs, especially the calves, difficulty with breathing, a sudden, severe headache, slurred speech, a sudden, unexplained shortness of breath, a sudden loss of coordination, or vision changes while using this medicine.\nUsing this medicine may increase your risk of having cancer of the breast or your reproductive organs (eg, endometrium, ovaries, cervix). Talk with your doctor about this risk. Check with your doctor immediately if your experience abnormal vaginal bleeding.\nCheck with your doctor immediately if you wear contact lenses or if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want an eye doctor (ophthalmologist) to check your eyes.\nCheck with your doctor right away if you have pain or tenderness in the upper stomach, dark urine or pale stools, or yellow eyes or skin. These could be symptoms of a serious liver problem.\nThis medicine may increase your risk of having gallbladder disease. Check with your doctor if you start to have stomach pains, nausea, and vomiting.\nCheck with your doctor before refilling an old prescription, especially after a pregnancy. You will need another physical examination and your doctor may change your prescription.\nMake sure any doctor or dentist who treats you knows that you are using this medicine. The results of some medical tests may be affected by this medicine. You may also need to stop using this medicine at least 4 weeks before and 2 weeks after having major surgery.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John\'s wort) or vitamin supplements.\n',NULL),(440,'juvisync','Take Juvisync exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nJuvisync is usually taken once daily in the evening.\nDo not crush, chew, or break the tablet. Swallow it whole.\nYour blood sugar will need to be checked often, and you may need other blood tests at your doctor\'s office.\nCheck your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor\'s advice.\nJuvisync is only part of a complete program of treatment that also includes diet, exercise, weight control, and possibly other medications. Follow your diet, medication, and exercise routines very closely.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\n Detailed Juvisync dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Juvisync can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid), or if you use certain other drugs, such as:\ncolchicine;\nfenofibric acid or fenofibrate;\nlomitapide;\nhigh doses of niacin (vitamin B3) or nicotinic acid;\ncertain heart rhythm medicines--amiodarone or dronedarone; or\nheart or blood pressure medication--amlodipine, diltiazem, ranolazine, or verapamil.\nThis list is not complete and many other drugs can interact with simvastatin and sitagliptin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.\n Juvisync drug interactions (more detail)\n','Get emergency medical help if you have any signs of an allergic reaction to Juvisync: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nIn rare cases, Juvisync can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.\nStop using Juvisync and call your doctor at once if you have:\nconfusion, memory problems;\nswelling, weight gain, urinating less than usual or not at all;\nsevere pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate;\nincreased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss;\nitching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or\nsevere skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.\nCommon Juvisync side effects may include:\ncold symptoms such as stuffy nose, sneezing, sore throat;\nheadache; or\nnausea, stomach pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Juvisync side effects (more detail)\n','Juvisync contains a combination of simvastatin and sitagliptin. Simvastatin is an HMG CoA reductase inhibitor, or \"statin.\" Simvastatin reduces levels of \"bad\" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of \"good\" cholesterol (high-density lipoprotein, or HDL).\nSitagliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.\nJuvisync is used in people with type 2 diabetes who also have high cholesterol or triglycerides (types of fat) in the blood. This medication is not for treating type 1 diabetes.\nJuvisync is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.\nJuvisync may also be used for purposes not listed in this medication guide.\n','Juvisync is a combination medicine for people with type 2 diabetes who also have high cholesterol.\nYou should not use Juvisync if you have liver disease or severe kidney disease. Do not use if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).\nDo not use Juvisync if you are pregnant, and stop taking the medicine if you become pregnant.\nDo not use this medicine if you are breast-feeding.\nCall your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Also call your doctor if you have severe pain in your upper stomach spreading to your back.\nThere are many other drugs that should not be used together with Juvisync. Tell your doctor about all other medicines you use. Do not consume grapefruit products while taking this medicine.\nBefore taking this medicine\nYou should not use Juvisync if you are allergic to simvastatin or sitagliptin, or if you have:\nliver disease;\nsevere kidney disease;\nif you are pregnant or breast-feeding; or\nif you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).\nThere are many other drugs that should not be used together with this medicine. Some medicines can cause unwanted or dangerous effects when used with Juvisync. Your doctor may need to change your treatment plan if you use any of the following drugs:\ncyclosporine;\ndanazol;\ngemfibrozil;\nnefazodone;\ncertain antibiotics--clarithromycin, erythromycin, or telithromycin;\ncertain antifungal medications--itraconazole, ketoconazole, posaconazole, or voriconazole;\nthe hepatitis C medications boceprevir or telaprevir; or\ncertain HIV/AIDS medications--atazanavir, cobicistat (Stribild, Tybost), indinavir, nelfinavir, ritonavir, saquinavir, or tipranavir.\nTo make sure Juvisync is safe for you, tell your doctor if you have:\na history of liver or kidney disease;\na history of pancreatitis;\na history of gallstones;\nhigh triglycerides (a type of fat in the blood);\nunderactive thyroid;\na history of alcoholism, or if you drink large amounts of alcohol; or\nif you use a blood thinner such as warfarin (Coumadin, Jantoven).\nThis medicine can harm an unborn baby or cause birth defects. Do not take Juvisync if you are pregnant. Stop taking the medicine and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking Juvisync.\nIt is not known whether this medication passes into breast milk or if it could harm a nursing baby. Do not breast-feed while you are taking Juvisync.\nDo not give this medication to anyone under 18 years old without medical advice.\n','Grapefruit and grapefruit juice may interact with simvastatin and sitagliptin and lead to unwanted side effects. Avoid the use of grapefruit products while taking Juvisync.\nAvoid eating foods that are high in fat or cholesterol. Simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.\nAvoid drinking alcohol. It can lower your blood sugar and may increase your risk of liver damage while taking this medicine.\n'),(441,'juxtapid','Usual Adult Dose for Hyperlipidemia:\nInitial dose: 5 mg orally once a day\nMaintenance dose: 5 to 60 mg orally once a day (should be individualized, taking into account the goal of therapy and the response to treatment)\nMaximum dose: 60 mg orally once a day.\nUsual Adult Dose for Homozygous Familial Hypercholesterolemia:\nInitial dose: 5 mg orally once a day\nMaintenance dose: 5 to 60 mg orally once a day (should be individualized, taking into account the goal of therapy and the response to treatment)\nMaximum dose: 60 mg orally once a day\nComments:\n-Dose should be escalated gradually based on response, safety, and tolerability. The dose may be escalated using the following incremental schedule: 5 mg orally once a day for a minimum of 2 weeks, then 10 mg, 20 mg, 40 mg, 60 mg orally once a day after a minimum of 4 weekly intervals between each dose increase.\n-Juxtapid should be taken with a full glass of water on an empty stomach at least 2 hours after the evening meal.\n Detailed Juxtapid dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Some medicines can make Juxtapid much less effective when taken at the same time. If you take cholestyramine or colesevelam, take your lomitapide dose 4 hours before or 4 hours after you take the other medicine.\nTell your doctor about all your current medicines. Many drugs can interact with lomitapide, especially:\nacetaminophen, isotretinoin, methotrexate, or tamoxifen;\nan antidepressant;\nantiviral medicine to treat HIV or hepatitis C;\nheart or blood pressure medicine;\nbirth control pills;\nan antibiotic - demeclocycline, doxycycline, minocycline, eravacycline, omadacycline, sarecycline, tetracycline;\na blood thinner - warfarin, Coumadin, Jantoven; or\ncholesterol medication - atorvastatin or simvastatin.\nThis list is not complete and many other drugs may affect lomitapide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Juxtapid drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction ro Juxtapid: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have signs of liver problems, such as:\nnausea, vomiting, upper stomach pain;\nloss of appetite;\nswelling around your midsection;\nflu-like symptoms, tiredness;\ndark urine, clay-colored stools; or\njaundice (yellowing of the skin or eyes).\nCommon Juxtapid side effects may include:\nstomach cramps;\nnausea, vomiting;\nindigestion; or\ndiarrhea.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Juxtapid side effects (more detail)\n','Juxtapid (lomitapide) is a cholesterol-lowering medication. It reduces blood levels of \"bad\" cholesterol, such as low-density lipoprotein (LDL) or non-high-density liproprotein (non-HDL), as well as a protein that carries bad cholesterol in the blood.\nJuxtapid is used together with a low-fat diet and other treatments to lower total cholesterol in people with homozygous familial hypercholesterolemia (an inherited type of high cholesterol).\nIt is not known whether Juxtapid will lower your risk of heart disease.\nJuxtapid is available only under a special program. You must be registered in the program and understand the risks and benefits of this medicine.\n','You should not use Juxtapid if you have severe liver disease or a history of abnormal liver function tests.\nDo not use if you are pregnant. Birth control pills may be less effective if you vomit or have diarrhea. Ask your doctor about the best way to prevent pregnancy while you are taking Juxtapid.\nTell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with lomitapide, and some drugs should not be used together.\nLomitapide can cause liver problems. Call your doctor at once if you have nausea, vomiting, upper stomach pain, tiredness, flu-like symptoms, dark urine, or jaundice (yellowing of the skin or eyes).\nBefore taking this medicine\nYou should not use Juxtapid if you are allergic to lomitapide, or if:\nyou have severe liver disease;\nyou have abnormal liver function tests; or\nyou are pregnant.\nMany drugs can interact and cause dangerous effects. Some drugs should not be used together with lomitapide. Your doctor may change your treatment plan if you also use:\naprepitant;\nconivaptan;\ncrizotinib, imatinib;\nnefazodone;\nan antibiotic - ciprofloxacin, clarithromycin, erythromycin, telithromycin;\nantifungal medication - fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole;\nheart or blood pressure medicine - diltiazem, verapamil;\nhepatitis C medication - boceprevir or telaprevir; or\nHIV or AIDS medicine - atazanavir, darunavir when given with ritonavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, tipranavir.\nTo make sure Juxtapid is safe for you, tell your doctor if you have:\nliver problems, even if caused by taking certain medicines;\nkidney disease (or if you are on dialysis);\nbowel problems, or an intestinal disorder;\nhereditary galactose intolerance, severe lactase deficiency, or glucose galactose malabsorption; or\nif you drink large amounts of alcohol.\nYou may need to have a negative pregnancy test before starting this treatment.\nDo not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Lomitapide could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine.\nIf you become pregnant, your name may be listed on a pregnancy registry to track the effects of lomitapide on the baby.\nBirth control pills may be less effective if you vomit or have diarrhea. Ask your doctor about the best way to prevent pregnancy while taking Juxtapid.\nYou should not breastfeed while using lomitapide.\nJuxtapid is not approved for use by anyone younger than 18 years old.\nHow should I take Juxtapid?\nJuxtapid is usually taken once daily, at least 2 hours after your evening meal. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nYour doctor will perform blood tests to make sure lomitapide is safe for you to take.\nTake Juxtapid on an empty stomach, at least 2 hours after your evening meal.\nSwallow the capsule whole and do not crush, chew, break, or dissolve it. Take this medicine with a full glass of water.\nYour doctor may have you take vitamin E or essential fatty acid supplements while you are taking Juxtapid. Take only the type and amount of vitamins or supplements your doctor has prescribed.\nYou will need frequent medical tests.\nJuxtapid is only part of a treatment program that may also include exercise and weight control. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\n','Avoid eating foods high in fat or cholesterol, or Juxtapid will not be as effective and may cause nausea, vomiting, and stomach pain.\nGrapefruit may interact with lomitapide and lead to unwanted side effects. Avoid the use of grapefruit products.\nDo not drink more than 1 alcoholic drink per day. Alcohol can increase your risk of liver damage while you are taking Juxtapid.\n'),(442,'jynarque','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nDrink plenty of fluids while taking Jynarque, but do not drink grapefruit juice or alcoholic drinks.\nYou may take Jynarque with or without food.\nSamsca is usually taken once per day and Jynarque is taken twice per day. Follow your doctor\'s dosing instructions very carefully.\nYou will need to be under observation in a hospital any time you start or restart treatment with Samsca, to quickly treat any serious side effects. If you stop taking Samsca for any length of time, do not start taking it again at home.\nLong-term use of Samsca can damage your liver. You should not use Samsca for longer than 30 days.\nYou can easily become dehydrated while taking Jynarque, which can lead to serious side effects. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual.\nYou will need frequent medical tests.\nStore at room temperature away from moisture and heat.\n Detailed Jynarque dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nSamsca: Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.\nJynarque: Skip the missed dose and use your next dose at the regular time.\nDo not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nMany drugs can affect Jynarque, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Jynarque drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nweakness, confusion, or a light-headed feeling (like you might pass out);\nirregular heartbeats;\nunexplained weight loss;\ndehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or\nliver problems--right-sided upper stomach pain, vomiting, loss of appetite, fever, itching, yellowing of your skin or eyes, not feeling well.\nSamsca is given to treat low levels of sodium in your blood, but can be dangerous if your sodium level rises too fast. Tell your doctor or caregivers at once if you have any of these signs that your hyponatremia is being reversed too quickly:\nproblems with speech or muscle control;\ntrouble swallowing;\ntrouble moving your arms and legs;\nconfusion, mood changes; or\na seizure.\nCommon side effects may include:\ndry mouth;\nincreased thirst or urination;\nhunger, fruity breath odor;\nconstipation; or\nweakness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Jynarque side effects (more detail)\n','Jynarque is used to slow the decline in kidney function in adults who have autosomal dominant polycystic kidney disease.\nSamsca is used to treat hyponatremia (low levels of sodium in your blood) in people with heart failure, and certain hormonal imbalances. Samsca improves urine flow without causing the body to lose too much sodium as you urinate.\nJynarque may also be used for purposes not listed in this medication guide.\n','You will need frequent medical tests before and during treatment with Jynarque.\nTell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.\nYou should not use Jynarque if you are dehydrated or unable to urinate, or if you can\'t tell when you are thirsty.\nYou also should not use Jynarque if you have ever had liver problems (other than polycystic liver disease), or if your sodium blood level is too high or too low.\nSamsca is given to treat low levels of sodium in your blood, but can be dangerous if this condition is reversed too quickly. Tell your caregivers at once if you have problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, confusion, or seizure.\nJynarque can cause serious or fatal liver problems. Call your doctor right away if you don\'t feel well and you have right-sided upper stomach pain, vomiting, loss of appetite, or yellowing of your skin or eyes.\nBefore taking this medicine\nYou should not use Jynarque if you are allergic to it, or if:\nyou are unable to urinate;\nyou are unable to tell that you are thirsty; or\nyou are severely dehydrated and feel like you might pass out.\nSamsca is not for use in people with autosomal dominant polycystic kidney disease (unless you receive Samsca through a special program that includes frequent liver function tests).\nYou should not take Samsca if your sodium level needs to be increased quickly.\nYou should not take Jynarque if you\'ve been told that your sodium blood level is too high or too low.\nSome medicines can cause unwanted or dangerous effects when used with Jynarque. Your doctor may change your treatment plan if you also use:\nnefazodone;\nan antibiotic--clarithromycin, telithromycin;\nantifungal medicine--itraconazole, ketoconazole; or\nHIV/AIDS medication--indinavir, nelfinavir, ritonavir, saquinavir.\nTell your doctor if you have ever had:\nkidney disease or urination problems;\nliver problems;\nallergies;\nif you drink large amounts of alcohol;\nif you are malnourished; or\nif you also use desmopressin (dDAVP), or a diuretic or \"water pill.\"\nIt is not known whether  Jynarque will harm an unborn baby. Tell your doctor if you are pregnant.\nYou should not breastfeed while using Jynarque.\n','Avoid alcoholic drinks.\nGrapefruit may interact with Jynarque and lead to unwanted side effects. Avoid the use of grapefruit products.\n'),(443,'k-dur','Usual Adult Dose for Hypokalemia:\nOral:\n40 to 100 mEq per day, orally, in 2 to 5 divided doses\nMaximum single dose: 20 mEq per dose\nMaximum daily dose: 200 mEq\nThe usual adult dietary intake is 50 to 100 mEq potassium per day.\n-Potassium depletion sufficient to cause hypokalemia usually requires the loss of 200 mEq or more of the total body stores of potassium.\nUsual Adult Dose for Prevention of Hypokalemia:\nOral:\nTypical dose: 20 mEq, orally, daily\n-Individualize dose based on serum potassium levels\n-Divide dose if more than 20 mEq per day is used\n-The usual adult dietary intake is 50 to 100 mEq potassium per day.\n Detailed K-Dur dosage information\n','Tell your doctor about all your current medicines and any you start or stop using, especially:\na diuretic or \"water pill\"; or\nheart or blood pressure medication.\nThis list is not complete. Other drugs may interact with potassium chloride, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n K-Dur drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to K-Dur: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using K-Dur and call your doctor at once if you have:\nsevere throat irritation;\nstomach bloating, severe vomiting, severe stomach pain;\nhigh potassium levels - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nCommon K-Dur side effects may include:\nnausea, vomiting, diarrhea;\ngas, stomach pain; or\nthe appearance of a K-Dur tablet in your stool.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n K-Dur side effects (more detail)\n','K-Dur tablets contain potassium chloride, a mineral that is found in many foods and is needed for several functions of your body, especially the beating of your heart.\nK-Dur is used to prevent or to treat low blood levels of potassium (hypokalemia). Potassium levels can be low as a result of a disease or from taking certain medicines, or after a prolonged illness with diarrhea or vomiting.\nK-Dur may also be used for purposes not listed in this medication guide.\n','You should not use K-Dur if you have high levels of potassium in your blood (hyperkalemia), or if you also take a \"potassium-sparing\" diuretic.\nTo be sure K-Dur is helping your condition, your blood may need to be tested often. Your heart rate may also be checked using an electrocardiograph or ECG (sometimes called an EKG) to measure electrical activity of the heart. This test will help your doctor determine how long to treat you with K-dur. Do not miss any scheduled appointments.\nSerious side effects of potassium include uneven heartbeat, muscle weakness or limp feeling, severe stomach pain, and numbness or tingling in your hands, feet, or mouth.\nDo not stop taking this medicine without first talking to your doctor. If you stop taking K-Dur suddenly, your condition may become worse.\nDo not crush, chew, break, or suck on an extended-release K-Dur tablet. Sucking on a K=Dur tablet can irritate your mouth or throat. Take K-Dur with food or just after a meal.\nBefore taking this medicine\nYou should not use K-Dur if you are allergic to potassium chloride, or if:\nyou have high levels of potassium in your blood (hyperkalemia); or\nyou take a \"potassium-sparing\" diuretic (water pill) such as amiloride, spironolactone, or triamterene.\nTo make sure K-Dur is safe for you, tell your doctor if you have ever had:\nkidney disease;\ncirrhosis or other liver disease;\nan adrenal gland disorder;\na large tissue injury such as a severe burn;\nsevere dehydration;\ndiabetes;\nheart disease or high blood pressure;\nstomach or intestinal bleeding;\na blockage in your stomach or intestines; or\nchronic diarrhea (such as ulcerative colitis, Crohn\'s disease).\nIt is not known whether K-Dur will harm an unborn baby. Your dose needs may be different during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether potassium chloride passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding. Your dose needs may be different while you are nursing.\nHow should I take K-Dur?\nTake K-Dur exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nTake K-Dur with a full glass of water. Take the medicine with food or just after a meal.\nDo not crush, chew, or suck a K-Dur tablet. Sucking on the tablet will irritate your mouth or throat.\nIf you are having difficulty swallowing the K-Dur tablet, you can dissolve the tablet in water.\nPlace the tablet in approximately half glass of water (4 fluid ounces).\nAllow approximately 2 minutes for the tablet to disintegrate.\nStir for about half a minute after the tablet has disintegrated.\nSwirl the suspension and consume the entire contents of the glass immediately by drinking or by the use of a straw.\nAdd another 1 fluid ounce of water, swirl, and consume immediately.\nThen, add an additional 1 fluid ounce of water, swirl, and consume immediately.\nTo be sure K-Dur is helping your condition, you may need frequent blood tests. You may not notice any change in your symptoms, but your blood work will help your doctor determine how long to treat you with K-Dur. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.\nYour treatment may include a special diet. Follow the diet plan created for you by your doctor or nutrition counselor. Get familiar with the list of foods you should eat or avoid to help control your condition.\nPotassium-rich foods include: squash, baked potatoes (skin on), spinach, lentils, broccoli, Brussels sprouts, zucchini, kidney or navy beans, raisins, watermelon, orange juice, bananas, cantaloupe, and low-fat milk or yogurt. Consume only the daily amounts recommended by your doctor or nutrition counselor.\nStore at room temperature away from moisture and heat. Keep the medication in a closed container.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include irregular heartbeats, chest pain, or muscle weakness.\n','Do not use potassium supplements or other products that contain potassium, unless your doctor has told you to. Salt substitutes or low-salt foods often contain potassium. Read the label of any food or medicine to see if it contains potassium.\n'),(444,'k-tab','This section provides information on the proper use of a number of products that contain potassium supplement.  It may not be specific to K-Tab. Please read with care.\nFor patients taking the liquid form of this medicine:\nThis medicine must be diluted in at least one-half glass (4 ounces) of cold water or juice to reduce its possible stomach-irritating or laxative effect.\nIf you are on a salt (sodium)-restricted diet, check with your doctor before using tomato juice to dilute your medicine. Tomato juice has a high salt content.\nFor patients taking the soluble granule, soluble powder, or soluble tablet form of this medicine:\nThis medicine must be completely dissolved in at least one-half glass (4 ounces) of cold water or juice to reduce its possible stomach-irritating or laxative effect.\nAllow any \"fizzing\" to stop before taking the dissolved medicine.\nIf you are on a salt (sodium)-restricted diet, check with your doctor before using tomato juice to dilute your medicine. Tomato juice has a high salt content.\nFor patients taking the extended-release tablet form of this medicine:\nSwallow the tablets whole with a full (8-ounce) glass of water. Do not chew or suck on the tablet.\nSome tablets may be broken or crushed and sprinkled on applesauce or other soft food. However, check with your doctor or pharmacist first, since this should not be done for most tablets.\nIf you have trouble swallowing tablets or if they seem to stick in your throat, check with your doctor. When this medicine is not properly released, it can cause irritation that may lead to ulcers.\nFor patients taking the extended-release capsule form of this medicine:\nDo not crush or chew the capsule. Swallow the capsule whole with a full (8-ounce) glass of water.\nSome capsules may be opened and the contents sprinkled on applesauce or other soft food. However, check with your doctor or pharmacist first, since this should not be done for most capsules.\nTake this medicine immediately after meals or with food to lessen possible stomach upset or laxative action.\nTake this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important if you are also taking both diuretics (water pills) and digitalis medicines for your heart.\nDosing\nThe dose medicines in this class will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor potassium bicarbonate\nFor oral dosage forms (tablets for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—25 to 50 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor potassium bicarbonate and potassium chloride\nFor oral dosage form (granules for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor oral dosage form (tablets for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20, 25, or 50 mEq dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor potassium bicarbonate and potassium citrate\nFor oral dosage form (tablets for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—25 or 50 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor potassium chloride\nFor long-acting oral dosage form (extended-release capsules):\nTo replace potassium lost by the body:\nAdults and teenagers—40 to 100 milliequivalents (mEq) a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nTo prevent potassium loss:\nAdults and teenagers—16 to 24 mEq a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor long-acting oral dosage forms (liquid for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 mEq mixed into one-half glass of cold water or juice, taken one to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq of potassium per kilogram (kg) (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed in water or juice.\nFor oral dosage form (powder for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—15 to 25 mEq dissolved in four to six ounces of cold water, taken two or four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq per kg (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be mixed into water or juice.\nFor oral dosage form (powder for suspension):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 mEq dissolved in two to six ounces of cold water, taken one to five times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor long-acting oral dosage form (extended-release tablets):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—6.7 to 20 mEq taken three times a day. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor oral dosage form (liquid for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight a day, taken in smaller doses during the day. The solution should be completely mixed into water or juice.\nFor oral dosage form (tablets):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—5 to 10 mEq taken two to four times a day. However, most people will not take more than 100 mEq a day.\nChildren—Dose must be determined by your doctor.\nFor potassium gluconate and potassium chloride\nFor oral dosage form (liquid for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 milliequivalents (mEq) diluted in 2 tablespoonfuls or more of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.\nFor oral dosage form (powder for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 mEq mixed in 2 tablespoonfuls or more of cold water or juice taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is base on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.\nFor potassium gluconate and potassium citrate\nFor oral dosage form (liquid for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.\nFor trikates\nFor oral dosage form (liquid for solution):\nTo prevent potassium loss or replace potassium lost by the body:\nAdults and teenagers—15 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken three or four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.\nChildren—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.\nMissed dose\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nKeep out of the reach of children.\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nDo not keep outdated medicine or medicine no longer needed.\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nStop taking this medicine and check with your doctor immediately if any of the following side effects occur:\nLess common\nConfusion\nirregular or slow heartbeat\nnumbness or tingling in hands, feet, or lips\nshortness of breath or difficult breathing\nunexplained anxiety\nunusual tiredness or weakness\nweakness or heaviness of legs\nCheck with your doctor as soon as possible if any of the following side effects occur:\nRare\nAbdominal or stomach pain, cramping, or soreness (continuing)\nchest or throat pain, especially when swallowing\nstools with signs of blood (red or black color)\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nMore common\nDiarrhea\nnausea\nstomach pain, discomfort, or gas (mild)\nvomiting\nSometimes you may see what appears to be a whole tablet in the stool after taking certain extended-release potassium chloride tablets. This is to be expected. Your body has absorbed the potassium from the tablet and the shell is then expelled.\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n','Potassium is needed to maintain good health. Although a balanced diet usually supplies all the potassium a person needs, potassium supplements may be needed by patients who do not have enough potassium in their regular diet or have lost too much potassium because of illness or treatment with certain medicines.\nThere is no evidence that potassium supplements are useful in the treatment of high blood pressure.\nLack of potassium may cause muscle weakness, irregular heartbeat, mood changes, or nausea and vomiting.\nInjectable potassium is administered only by or under the supervision of your doctor. Some forms of oral potassium may be available in stores without a prescription. Since too much potassium may cause health problems, you should take potassium supplements only if directed by your doctor.\nImportance of Diet\nFor good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods.\nThe following table includes some potassium-rich foods.\nFood (amount)\nMilligrams\nof potassium\nMilliequivalents\nof potassium\nAcorn squash, cooked\n(1 cup)\n896\n23\nPotato with skin, baked\n(1 long)\n844\n22\nSpinach, cooked\n(1 cup)\n838\n21\nLentils, cooked\n(1 cup)\n731\n19\nKidney beans, cooked\n(1 cup)\n713\n18\nSplit peas, cooked\n(1 cup)\n710\n18\nWhite navy beans, cooked\n(1 cup)\n669\n17\nButternut squash, cooked\n(1 cup)\n583\n15\nWatermelon\n(1/16)\n560\n14\nRaisins\n(½ cup)\n553\n14\nYogurt, low-fat, plain\n(1 cup)\n531\n14\nOrange juice, frozen\n(1 cup)\n503\n13\nBrussel sprouts, cooked\n(1 cup)\n494\n13\nZucchini, cooked, sliced\n(1 cup)\n456\n12\nBanana\n(medium)\n451\n12\nCollards, frozen, cooked\n(1 cup)\n427\n11\nCantaloupe\n(¼)\n412\n11\nMilk, low-fat 1%\n(1 cup)\n348\n9\nBroccoli, frozen, cooked\n(1 cup)\n332\n9\nThe daily amount of potassium needed is defined in several different ways.\nFor U.S.—\nRecommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person\'s age, sex, and physical condition (e.g., pregnancy).\nDaily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).\nFor Canada—\nRecommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.\nBecause lack of potassium is rare, there is no RDA or RNI for this mineral. However, it is thought that 1600 to 2000 mg (40 to 50 milliequivalents [mEq]) per day for adults is adequate.\nRemember:\nThe total amount of potassium that you get every day includes what you get from food and what you may take as a supplement. Read the labels of processed foods. Many foods now have added potassium.\nYour total intake of potassium should not be greater than the recommended amounts, unless ordered by your doctor. In some cases, too much potassium may cause muscle weakness, confusion, irregular heartbeat, or difficult breathing.\n','Your doctor should check your progress at regular visits to make sure the medicine is working properly and that possible side effects are avoided. Laboratory tests may be necessary.\nDo not use salt substitutes, eat low-sodium foods, especially some breads and canned foods, or drink low-sodium milk unless you are told to do so by your doctor, since these products may contain potassium. It is important to read the labels carefully on all low-sodium food products.\nCheck with your doctor before starting any physical exercise program, especially if you are out of condition and are taking any other medicine. Exercise and certain medicines may increase the amount of potassium in the blood.\nCheck with your doctor at once if you notice blackish stools or other signs of stomach or intestinal bleeding. This medicine may cause such a condition to become worse, especially when taken in tablet form.\n',NULL);
