Rabeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.
Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.
Rabeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.
You may be more likely to have a broken bone while taking  rabeprazole long term or more than once per day.
Before taking this medicine
Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.
You should not use this medicine if you are allergic to rabeprazole or:
if you also take any medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey);
if you had breathing problems, kidney problems, or a severe allergic reaction after taking rabeprazole in the past; or
if you are also allergic to medicines like rabeprazole, such as esomeprazole, lansoprazole, omeprazole, pantoprazole , Nexium, Prevacid, Prilosec, Protonix, and others.
Tell your doctor if you have ever had:
liver disease;
osteoporosis or low bone mineral density (osteopenia);
lupus (an autoimmune disorder); or
low levels of magnesium in your blood.
You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.
Tell your doctor if you are pregnant or breastfeeding.
Do not give this medicine to a child without medical advice. Certain forms and strengths of rabeprazole should not be given to a child younger than 12 years old.
