Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
You should not use fluconazole if you are allergic to it.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with fluconazole. Your doctor may change your treatment plan if you also use:
cisapride, fentanyl, methadone, pimozide, tofacitinib, tolvaptan, or a vitamin A supplement;
an antibiotic, antifungal, or antiviral medicine;
a blood thinner;
cancer medicine;
cholesterol medication;
oral diabetes medicine;
heart or blood pressure medication;
medicine for malaria or tuberculosis;
medicine to prevent organ transplant rejection;
medicine to treat depression or mental illness;
an NSAID (nonsteroidal anti-inflammatory drug);
seizure medicine; or
steroid medicine.
Tell your doctor if you have ever had:
liver disease;
heart problems; or
if you are allergic to other antifungal medicine (such as ketoconazole, itraconazole, miconazole, posaconazole, voriconazole, and others).
The liquid form of fluconazole contains sucrose. Talk to your doctor before using this form of fluconazole if you have a problem digesting sugars or milk.
Fluconazole may harm an unborn baby. Use effective birth control to prevent pregnancy while taking  fluconazole and for at least 1 week after your last dose.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
