Usual Adult Dose for Depression:
Immediate release:
-Initial dose: 37.5 mg orally twice a day OR 25 mg orally 3 times a day
-Maintenance dose: 75 to 150 mg orally per day, given in divided doses
-Maximum dose:
---Moderately depressed outpatients: 225 mg/day
---Severely depressed inpatients: 375 mg/day
Extended release:
-Initial dose: 75 mg orally once a day
-Maintenance dose: 75 to 225 mg orally once a day
-Maximum dose:
---Moderately depressed outpatients: 225 mg/day
---Severely depressed inpatients: 375 mg/day
Comments:
-The daily dosage of immediate-release formulations may be divided into 2 or 3 doses/day.
-Healthcare providers should consider initial extended release doses of 37.5 mg orally once a day for 4 to 7 days (before increasing the dose to 75 mg/day) in patients who may require additional time to adjust to the drug.
-Doses may be increased in daily increments of up to 75 mg orally at intervals of no less than 4 days.
-Patients should be periodically reassessed for the continued need of maintenance treatment and for the appropriate dose of treatment.
-Use of doses exceeding 225 mg/day is limited.
Use: Treatment of major depressive disorder (MDD)
Usual Adult Dose for Generalized Anxiety Disorder:
Extended release:
-Initial dose: 75 mg orally once a day
-Maintenance dose: 75 to 225 mg orally once a day
-Maximum dose: 225 mg/day
Comments:
-Healthcare providers should consider initial extended release doses of 37.5 mg orally once a day for 4 to 7 days (before increasing the dose to 75 mg/day) in patients who may require additional time to adjust to the drug.
-Doses may be increased in daily increments of up to 75 mg orally at intervals of no less than 4 days.
Use: Treatment of generalized anxiety disorder (GAD)
Usual Adult Dose for Social Anxiety Disorder:
Extended release: 75 mg orally once a day
Comment: There is no evidence that doses greater than 75 mg/day confer additional benefit.
Uses:
-Treatment of social anxiety disorder (SAD)
-Treatment of social phobia
Usual Adult Dose for Panic Disorder:
Extended release:
-Initial dose: 37.5 mg orally once a day for 7 days, then 75 mg orally once a day thereafter
-Maintenance dose: 75 to 225 mg orally once a day
-Maximum dose: 225 mg/day
Comment: Doses may be increased in daily increments of 75 mg orally at intervals of no less than 7 days.
Use: Treatment of Panic Disorder (PD), with or without agoraphobia
 Detailed Venlafaxine dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
