Using Imitrex while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "serotonin syndrome," which can be fatal. Tell your doctor if you also use:
medicine to treat depression or a psychiatric disorder;
medicine for Parkinson's disease;
medicine for serious infections;
herbal products;
stimulant medicine;
opioid medicine; or
medicine to prevent nausea and vomiting.
This list is not complete. Other drugs may interact with sumatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Imitrex drug interactions (more detail)
