Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take  sulfasalazine after a meal.
Swallow the tablet whole and do not crush, chew, or break it.
You will need frequent medical tests.
Drink plenty of liquids to keep your kidneys working properly while you are taking sulfasalazine.
Sulfasalazine can affect the results of certain medical tests. Tell any doctor who treats you that you are using sulfasalazine.
Sulfasalazine may cause your skin or urine to appear orange-yellow in color. Call your doctor if you also have yellowing of your eyes, brown urine, or stomach pain. These may be signs of liver problems.
If you are treating arthritis, do not stop using any of your other arthritis medicines until your doctor tells you to. Sulfasalazine may not improve your symptoms right away, and you may still need your other medicines for awhile.
Sulfasalazine is only part of a complete treatment for rheumatoid arthritis that may also include rest and physical therapy. Follow your doctor's instructions very closely.
Store at room temperature away from moisture and heat.
 Detailed Sulfasalazine dosage information
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What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include vomiting, stomach pain, drowsiness, or seizure.
