Get emergency medical help if you have signs of an allergic reaction to Annovera: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
very high blood pressure - severe headache, blurred vision, pounding in your neck or ears;
signs of a blood clot - sudden numbness or weakness (especially on one side of the body), sudden severe headache, problems with speech or vision, stabbing chest pain, feeling short of breath, pain or numbness in one or both legs;
heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
toxic shock syndrome - sudden fever, body aches, skin rash, vomiting, diarrhea, and feeling dizzy or light-headed;
new headaches, or a change in the pattern or severity of migraine headaches;
jaundice (yellowing of the skin or eyes); or
symptoms of depression - mood changes, thoughts about hurting yourself.
Common Annovera side effects may include:
headache;
nausea, vomiting, diarrhea, stomach pain;
vaginal itching or discharge;
menstrual pain, breast tenderness;
irregular vaginal bleeding; or
pain or burning when you urinate;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Ethinyl estradiol/segesterone side effects (more detail)
