Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
signs of a stroke--sudden numbness or weakness (especially on one side of the body), severe headache, problems with vision or speech;
signs of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, swelling or pain in an arm or leg;
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
severe headache, pounding in your neck or ears;
jaundice (yellowing of the skin or eyes);
swelling in your hands, ankles, or feet;
a change in the pattern or severity of migraine headaches; or
symptoms of depression--sleep problems, weakness, tired feeling, mood changes.
Common side effects may include:
breast pain or swelling;
nausea;
menstrual cramps, breakthrough bleeding;
headache, anxiety, mood changes; or
skin reactions where a patch was worn--redness, irritation, itching, rash, pain, or swelling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Xulane side effects (more detail)
