Misoprostol can cause birth defects, premature birth, uterine rupture, miscarriage, or incomplete miscarriage and dangerous uterine bleeding. Do not use misoprostol if you are pregnant.
If you are able to become pregnant, you will need to have a negative pregnancy test before starting this treatment. You will also need to use effective birth control to prevent pregnancy during treatment.
Before taking this medicine
You should not use  misoprostol if you are allergic to misoprostol or other prostaglandins, or if you are pregnant.
To make sure misoprostol is safe for you, tell your doctor if you have:
inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), or other intestinal problems;
heart disease; or
if you are dehydrated.
FDA pregnancy category X. Misoprostol can cause birth defects, premature birth, uterine rupture, miscarriage, or incomplete miscarriage and dangerous uterine bleeding. Do not use misoprostol if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine, and for at least 1 month after your treatment ends.
If you are able to become pregnant, you will need to have a negative pregnancy test before you start taking misoprostol. Treatment with this medicine should begin on the second or third day of your menstrual period.
Stop taking this medicine and tell your doctor right away if you become pregnant during treatment.
It is not known whether misoprostol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
