Metamucil can make it harder for your body to absorb other medicines you take by mouth, possibly making them less effective. If you take any oral medicines, take them 2 hours before or 2 hours after you take this medicine.
Other drugs may affect Metamucil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
 Metamucil drug interactions (more detail)
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