Many drugs can interact with methylene blue. Tell your doctor about all other medications you use. You may need to stop using certain medicines (in some cases for up to 5 weeks before you start treatment with  Uribel). However, do not stop taking any of your medications without your doctor's advice. This includes:
any type of antidepressant;
diet pills, stimulants, cold or allergy medicines, ADHD medication;
narcotic pain medicine;
medication to treat Parkinson's disease or restless leg syndrome; or
a "triptan" migraine headache medication.
Taking any of the above medications while you are treated with medicine that contains methylene blue can cause high levels of serotonin in the body. Call your doctor right away if you have symptoms of this condition: agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, or fainting.
Many drugs can interact with this medicine. Not all possible interactions are listed here. Also, hyoscyamine can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all your medications and any you start or stop using, especially:
a diuretic or "water pill";
medicines that change the acidity of your urine--sodium bicarbonate, potassium citrate, sodium citrate with citric acid or potassium;
bladder or urinary medicines--darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin; or
a sulfa drug.
This list is not complete and many other drugs can interact with Uribel. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
 Uribel drug interactions (more detail)
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