When you start or stop taking Crestor, your doctor may need to adjust the doses of any other medicines you take on a regular basis. Using certain medicines together with rosuvastatin can increase your risk of serious muscle problems. It is very important to tell your doctor about all medicines you use, and those you start or stop using during your treatment with Crestor, especially:
colchicine;
cyclosporine;
another "statin" medicine - atorvastatin, lovastatin, simvastatin, Lipitor, Pravachol, Zocor, Vytorin, and others;
antiviral medicine to treat HIV or hepatitis C - atazanavir, fosamprenavir, ledipasvir, lopinavir, ritonavir, simeprevir, sofosbuvir, tipranavir, Epclusa, Mavyret, Viekira, Vosevi, and others;
a blood thinner - warfarin, Coumadin, Jantoven;
cancer medicine - darolutamide, regorafenib;
other cholesterol medications - fenofibrate, gemfibrozil; or
medicines that contain niacin or nicotinic acid - vitamin B3, Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others.
This list is not complete. Other drugs may interact with rosuvastatin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
 Crestor drug interactions (more detail)
