There are many other drugs that can make Odefsey less effective and should not be used at the same time. Tell your doctor about all your the medicines you use.
Odefsey may cause a serious condition called lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.
If you have hepatitis B you may develop liver symptoms after you stop taking Odefsey. Your doctor may want to check your liver function for several months after you stop using Odefsey.
Before taking Odefsey
You should not take Odefsey if you are allergic to emtricitabine, rilpivirine, or tenofovir.
Do not take Odefsey with other medicines that also contain emtricitabine, rilpivirine, tenofovir, adefovir, or lamivudine.
There are many other drugs that can make rilpivirine less effective and should not be used at the same time:
dexamethasone;
St. John's wort;
tuberculosis medication - rifabutin, rifampin, rifapentine;
seizure medicine - carbamazepine, oxcarbazepine, phenobarbital, phenytoin; or
stomach acid reducers - dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole.
To make sure Odefsey is safe for you, tell your doctor if you have ever had:
kidney disease;
liver disease (including hepatitis B or C);
depression or mental illness; or
long QT syndrome (in you or a family member)./p>
Some people taking tenofovir develop a serious condition called lactic acidosis. This may be more likely in women, in people who are overweight or have liver disease, and in people who have taken HIV/AIDS medication for a long time. Talk with your doctor about your risk.
HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection. Tell your doctor if you become pregnant during treatment. If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of the medicine on the baby.
Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Odefsey is not approved for use by anyone younger than 12 years old or weighing less than 77 pounds (35 kilograms).
