Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.
Serious infections may occur during treatment with ustekinumab. Call your doctor right away if you have signs of infection such as: fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.
Also call your doctor at once if you have:
a mole that has changed in size or color;
swelling, pain, warmth, or redness anywhere on your body;
stomach pain that is sudden and severe or comes on slowly, changes in bowel habits (diarrhea or constipation);
new or worsening cough, sudden chest pain, feeling short of breath;
pain or burning when you urinate; or
severe headache, confusion, change in mental status, vision problems, and/or seizure (convulsions).
Common side effects may include:
fever, flu-like symptoms;
itching;
stomach pain, nausea, vomiting, diarrhea;
vaginal itching or discharge;
pain or burning when you urinate;
cough with mucus, shortness of breath, chest discomfort;
headache, tiredness; or
redness where ustekinumab was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Ustekinumab side effects (more detail)
