Usual Adult Dose for Paroxysmal Nocturnal Hemoglobinuria:
40 kg to less than 60 kg:
-Loading dose: 2400 mg IV
-Maintenance dose: 3000 mg IV every 8 weeks starting 2 weeks after the loading dose
60 kg to less than 100 kg:
-Loading dose: 2700 mg IV
-Maintenance dose: 3300 mg IV every 8 weeks starting 2 weeks after the loading dose
100 kg or greater:
-Loading dose: 3000 mg IV
-Maintenance dose: 3600 mg IV every 8 weeks starting 2 weeks after the loading dose.
Use: For the treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH)
Usual Adult and Pediatric Dose for Hemolytic Uremic Syndrome:
5 kg to less than 10 kg:
-Loading dose: 600 mg IV
-Maintenance dose: 300 mg IV every 4 weeks starting 2 weeks after the loading dose
10 kg to less than 20 kg:
-Loading dose: 600 mg IV
-Maintenance dose: 600 mg IV every 4 weeks starting 2 weeks after the loading dose
20 kg to less than 30 kg:
-Loading dose: 900 mg IV
-Maintenance dose: 2100 mg IV every 8 weeks starting 2 weeks after the loading dose
30 kg to less than 40 kg:
-Loading dose: 1200 mg IV
-Maintenance dose: 2700 mg IV every 8 weeks starting 2 weeks after the loading dose
40 kg to less than 60 kg:
-Loading dose: 2400 mg IV
-Maintenance dose: 3000 mg IV every 8 weeks starting 2 weeks after the loading dose
60 kg to less than 100 kg:
-Loading dose: 2700 mg IV
-Maintenance dose: 3300 mg IV every 8 weeks starting 2 weeks after the loading dose
100 kg or greater:
-Loading dose: 3000 mg IV
-Maintenance dose: 3600 mg IV every 8 weeks starting 2 weeks after the loading dose.
Use: For the treatment of adults and pediatric patients one month and older with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy (TMA)
 Detailed Ultomiris dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Ultomiris injection.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
