You should not use Annovera if you have: uncontrolled high blood pressure, heart problems, coronary artery disease, reduced blood flow to your brain, long-term diabetes (or health problems caused by diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe headaches, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.
You should not use Annovera if you smoke and are older than 35 years of age.
Do not use the Annovera vaginal ring if you are pregnant or if you have recently had a baby.
Before taking this medicine
You should not use Annovera if you are allergic to ethinyl estradiol or segesterone, or if you have:
uncontrolled high blood pressure (especially if you also have blood vessel damage);
heart problems (coronary artery disease, heart rhythm disorder, a heart valve disorder, history of heart attack, stroke, or blood clot);
reduced blood flow to your brain;
an increased risk of having blood clots due to a heart problem or a hereditary blood disorder;
diabetes (and you are over 35 years old, or have had diabetes longer than 20 years);
a diabetes-related health problem (vision problems, kidney problems, nerve damage, circulation problems);
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;
unusual vaginal bleeding that has not been checked by a doctor;
migraines or severe headaches with vision changes;
liver disease or liver cancer; or
if you have taken any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir in the past 2 weeks.
You should not use Annovera if you smoke and are older than 35 years of age. Using this medicine can increase your risk of blood clots, stroke, or heart attack, especially if you smoke.
To make sure Annovera is safe for you, tell your doctor if you have ever had:
heart disease, high blood pressure, or if you are prone to having blood clots;
high cholesterol or triglycerides (a type of fat in the blood);
liver disease or jaundice (yellowing of your skin or eyes);
kidney disease;
diabetes, gallbladder disease;
depression, migraine headaches, or a seizure;
toxic shock syndrome, or easy vaginal irritation;
a family history of stroke or breast cancer;
a breast lump, fibrocystic breast disease, or an abnormal mammogram; or
if you have recently had a miscarriage or abortion.
Do not use a Annovera vaginal ring if you are pregnant, or if you had a baby within the past 4 weeks. Call your doctor if you miss a period or think you may be pregnant.
You should not breastfeed while using Annovera.
Annovera is not approved for any woman who has not yet had a menstrual period, or a woman no longer having periods.
