Kisqali can cause serious side effects on your heart, liver, or lungs. Call your doctor at once if you have chest pain, fast or pounding heartbeats, trouble breathing, cough (with or without mucus), sudden dizziness, right-sided upper stomach pain, loss of appetite, unusual bleeding or bruising, dark urine, or yellowing of your skin or eyes.
You will need frequent medical tests while taking Kisqali. Your cancer treatments may be delayed based on the results of these tests. Tell your doctor if you have signs of infection, such as fever or chills.
Before taking this medicine
You should not use Kisqali if you are allergic to ribociclib, or if you also take tamoxifen.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Kisqali.
To make sure Kisqali is safe for you, tell your doctor if you have ever had:
slow heartbeats;
heart disease or prior heart attack;
long QT syndrome;
an electrolyte imbalance (such as low levels of calcium, magnesium, phosphorus, or potassium in your blood);
liver disease;
kidney disease; or
signs of infection (fever, chills).
Tell your doctor whether or not you have gone through menopause.
You may need to have a negative pregnancy test before starting this treatment.
Do not use Kisqali if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.
This medicine may affect fertility (ability to have children) in men. Talk with your doctor if you have concerns about this risk.
You should not breastfeed while using Kisqali and for at least 3 weeks after your last dose.
How should I take Kisqali?
Take Kisqali exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Kisqali is given in a 28-day treatment cycle. You will take the medicine for the first 21 days of each cycle, followed by 7 days off. Your doctor will determine how long to treat you with Kisqali.
Swallow the tablet whole and do not crush, chew, or break it.
Take the medicine at the same time each morning, with or without food.
If you vomit after taking the medicine, wait until the next day to take your next dose.
Do not use a broken or damaged pill.
You may need frequent medical tests to be sure Kisqali is not causing harmful effects. Your cancer treatments may be delayed based on the results.
Store in the original container at room temperature, away from moisture and heat.
