Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Diazepam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. A person caring for you should seek emergency medical attention if you have weak or shallow breathing, if you are hard to wake up, or if you stop breathing.
Call your doctor at once if the person receiving this medicine has:
new or worsening seizures;
unusual changes in mood or behavior;
thoughts of suicide or hurting yourself;
confusion, hallucinations;
sleep problems; or
anxiety, excitement, anger, or feeling restless.
The sedative effects of diazepam rectal may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are using Diastat AcuDial.
Common side effects may include:
drowsiness, dizziness, headache, feeling nervous;
problems with coordination or muscle movement;
flushing (sudden warmth, redness, or tingly feeling);
stomach pain, diarrhea; or
rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Diastat AcuDial side effects (more detail)
