Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Desyrel is not approved for use by anyone younger than 18 years old.
Before taking this medicine
You should not use Desyrel if you are allergic to it.
Do not use Desyrel if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
After you stop taking Desyrel, you must wait at least 14 days before you start taking an MAOI.
Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with Desyrel could cause a serious condition called serotonin syndrome.
Tell your doctor if you have ever had:
liver or kidney disease;
heart disease, or a recent heart attack;
a bleeding or blood clotting disorder;
seizures or epilepsy;
narrow-angle glaucoma;
long QT syndrome;
drug addiction or suicidal thoughts; or
bipolar disorder (manic depression).
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Taking  Desyrel during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop Desyrel without asking your doctor.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of trazodone on the baby.
Ask a doctor if it is safe to breastfeed while using this medicine.
Desyrel is not approved for use by anyone younger than 18 years old.
