The possible side effects of are:
constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.
Get emergency medical help if you have:
trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, lightheadedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.
These are not all the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
 Xtampza ER side effects (more detail)
Instructions for Use
Always take Xtampza ER with approximately the same amount of food.
If you cannot swallow the capsules, tell your healthcare provider. If your healthcare provider tells you that you can take Xtampza ER by sprinkling the capsule contents, follow these steps:
Xtampza ER can be opened and the contents inside the capsule can be sprinkled onto soft foods (such as, applesauce, pudding, yogurt, ice cream, or jam) as follows:
Open the capsule and sprinkle the contents over about one tablespoon of the soft food listed above.
Swallow all of the soft food and sprinkled capsule contents right away. Do not save any of the soft food and capsule contents for another dose.
Rinse your mouth to make sure you have swallowed all of the capsule contents.
Flush the empty capsule down the toilet right away.
The capsule contents can also be sprinkled into a cup and then put directly into the mouth.
Giving Xtampza ER through a nasogastric or gastrostomy tube: Use water, milk, or a liquid nutritional supplement to flush the tube when giving Xtampza ER.
Step 1: Flush the nasogastric or gastrostomy tube with liquid.
Step 2: Open a capsule and carefully pour the contents of the capsule directly into the tube. Do not pre-mix the capsule contents with the liquid used to flush the capsule contents through the tube.
Step 3: Draw up 15 mL of liquid into a syringe, insert the syringe into the tube, and flush the contents of the capsule through the tube to give the dose.
Step 4: Flush the tube two more times, each time with 10 mL of liquid, to ensure that none of the contents of the capsule are left in the tube.
