Get emergency medical help if you have signs of an allergic reaction to Otezla: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
severe diarrhea, nausea, and vomiting;
unexplained weight loss, or if you lose a lot of weight;
mood changes, new or worsening depression; or
thoughts of suicide or hurting yourself.
Common Otezla side effects may include:
nausea, diarrhea;
headache; or
cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Otezla side effects (more detail)
