Taking Topamax with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, opioid pain medication, muscle relaxer, or medicine for anxiety or depression.
Tell your doctor about all your current medicines and any you start or stop using, especially:
zonisamide;
birth control pills;
divalproex, valproic acid; or
other glaucoma medications, including eye drops.
This list is not complete. Other drugs may interact with topiramate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
 Topamax drug interactions (more detail)
