Fatal side effects can occur if you take Xywav with other drugs that cause drowsiness or slow your breathing. Ask your doctor before taking cold or allergy medicine, opioid medication, sedatives, muscle relaxers, seizure medicine, or medicine for depression, anxiety, or mental illness.
If you start or stop taking divalproex (Depakote), your doctor may need to adjust your Xywav dose.
Other drugs may interact with Xywav, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
 Xywav drug interactions (more detail)
