Usual Adult Dose for Edema:
Hydrochlorothiazide 25 to 50 mg-Triamterene 37.5 to 100 mg orally once a dayComments:-Patients who become hypokalemic on 50 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 50 mg-triamterene 75 mg orally once a day.  Patients who become hypokalemic on 25 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day.-Patients in whom hypokalemia cannot be risked may be initiated on hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day.Uses:-Treatment of hypertension or edema in patients who develop hypokalemia on hydrochlorothiazide alone.-Initial therapy of hypertension or edema for patients in whom hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations or with a history of cardiac arrhythmias, etc.).
Usual Adult Dose for Hypertension:
Hydrochlorothiazide 25 to 50 mg-Triamterene 37.5 to 100 mg orally once a dayComments:-Patients who become hypokalemic on 50 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 50 mg-triamterene 75 mg orally once a day.  Patients who become hypokalemic on 25 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day.-Patients in whom hypokalemia cannot be risked may be initiated on hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day.Uses:-Treatment of hypertension or edema in patients who develop hypokalemia on hydrochlorothiazide alone.-Initial therapy of hypertension or edema for patients in whom hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations or with a history of cardiac arrhythmias, etc.).
 Detailed Hydrochlorothiazide/triamterene dosage information
What other drugs can affect hydrochlorothiazide and triamterene?
Tell your doctor about all your other medicines, especially:
any other blood pressure medicine;
amphotericin B;
chlorpropamide;
digoxin;
laxatives;
lithium;
methenamine;
a blood thinner;
oral diabetes medicine;
steroid medication (prednisone and others);
an ACE inhibitor--benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril; or
NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may affect hydrochlorothiazide and triamterene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
