Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
You should not use  rifampin if you are allergic to rifampin or similar medicines such as rifabutin, rifapentine, rifamycin, or rifaximin.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with rifampin. Your doctor may change your treatment plan if you also use: atazanavir, darunavir, fosamprenavir, praziquantel, ritonavir, saquinavir, or tipranavir.
Tell your doctor if you have ever had:
diabetes;
liver disease;
bleeding problems; or
porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
It is not known whether this medicine will harm an unborn baby. However, using rifampin during the last few weeks of pregnancy may cause bleeding in the mother or the newborn baby. Tell your doctor if you are pregnant.
Rifampin can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using rifampin, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
You should not breastfeed while using this medicine.
