Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
If you also take an antacid: Wait at least 3 hours after taking the antacid before you take Nerlynx.
If you also take a stomach acid reducer: Take your Nerlynx dose 2 hours before or 10 hours after you take the other medicine (this includes cimetidine, famotidine, nizatidine, ranitidine, Axid, Pepcid, Tagamet, Zantac, and others).
You should not use certain stomach acid reducers, such as esomeprazole, lansoprazole, omeprazole, pantoprazole Nexium, Prevacid, Prilosec, Protonix, and others.
Other drugs may interact with neratinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
 Nerlynx drug interactions (more detail)
