Get emergency medical help if you have signs of an allergic reaction to Brukinsa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Zanubrutinib can cause serious or life-threatening side effects. Call your doctor at once if you have:
pounding heartbeats or fluttering in your chest;
chest discomfort;
a light-headed feeling, like you might pass out;
liver problems - right-sided upper stomach pain, vomiting, loss of appetite, yellowing of your skin or eyes, and not feeling well;
low platelets in your blood - easy bruising, unusual bleeding, purple or red spots under your skin;
low red blood cells - pale skin, weakness, unusual tiredness, feeling light-headed or short of breath, cold hands and feet, fast or irregular heartbeat;
low white blood cell counts - fever, mouth sores, skin sores, sore throat, cough, trouble breathing;
signs of bleeding inside your body - red or pink urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds, severe headache, vision problems, numbness or weakness on one side, trouble speaking or understanding what is said to you; or
signs of infection - fever, chills, redness or swelling, cough with mucus, feeling short of breath.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Brukinsa side effects may include:
diarrhea;
low platelet or other blood cell counts;
easy bruising or bleeding;
rash; or
cold symptoms such as stuffy nose, sneezing, sore throat or cough.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Brukinsa side effects (more detail)
