Taking Viibryd with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Many drugs can interact with vilazodone. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:
any other antidepressant;
a diuretic or "water pill";
mephenytoin;
St. John's wort;
a blood thinner - warfarin, Coumadin, Jantoven;
medicine to treat anxiety, mood disorders, thought disorders, or mental illness - amitriptyline, buspirone, desipramine, lithium, nortriptyline, and many others;
medicine to treat ADHD or narcolepsy - Adderall, Concerta, Ritalin, Vyvanse, Zenzedi, and others;
migraine headache medicine - rizatriptan, sumatriptan, zolmitriptan, and others;
narcotic and other pain medicine - fentanyl, tramadol.
NSAIDs - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others;
antifungal medication - itraconazole, voriconazole;
certain antibiotics - clarithromycin, rifampin; or
digoxin.
This list is not complete and many other drugs can interact with vilazodone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
 Viibryd drug interactions (more detail)
