Usual Adult Dose for Paget's Disease:
5 mg IV infusion, at a constant infusion rate, over no less than 15 minutes
Calcium and vitamin D supplementation:
-Calcium: 750 mg elemental calcium orally twice a day, or 500 mg orally three times a day
-Vitamin D: 800 international units orally daily, especially in the 2 weeks following drug administration
Comments: Retreatment may be considered in patients who have relapsed, based on increases in serum alkaline phosphatase or failure to achieve normalization of serum alkaline phosphatase.
Uses: Paget's disease of bone with elevations in serum alkaline phosphatase of two times or higher than upper limit of age- specific normal reference range
Usual Adult Dose for Osteoporosis:
5 mg IV infusion over no less than 15 minutes, once a year
Comments: An average of at least 1200 mg calcium and 800 to 1000 international units vitamin D daily is recommended.
Uses:
-Osteoporosis in postmenopausal women, diagnosed by bone mineral density or prevalent vertebral fracture (this drug reduces the incidence of fractures).
-To increase bone mass in men with osteoporosis.
-Treatment of glucocorticoid-induced osteoporosis in men and women who are either initiating or continuing systemic glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and are expected to remain on glucocorticoids for at least 12 months.
Usual Adult Dose for Prevention of Osteoporosis:
5 mg IV infusion over no less than 15 minutes, every 2 years
Uses:
-Prevention of osteoporosis in postmenopausal women.
-Prevention of glucocorticoid-induced osteoporosis in men and women who are either initiating or continuing systemic glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and are expected to remain on glucocorticoids for at least 12 months.
 Detailed Reclast dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Reclast injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
