Do not use Trintellix if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, methylene blue injection, phenelzine, tranylcypromine, and others. After you stop taking Trintellix you must wait at least 21 days before you start taking an MAO inhibitor.
Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Do not give Trintellix to anyone younger than 18 years old without the advice of a doctor. This medicine is not approved for use in children.
Before taking this medicine
You should not use Trintellix if you are allergic to vortioxetine.
After you stop taking Trintellix you must wait at least 21 days before you start taking an MAO inhibitor.
Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with vortioxetine could cause a serious condition called serotonin syndrome.
To make sure Trintellix is safe for you, tell your doctor if you have ever had:
bipolar disorder (manic depression), or a history of drug abuse or suicidal thoughts;
glaucoma;
seizures or epilepsy;
bleeding problems; or
low levels of sodium in your blood.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Trintellix is not approved for use by anyone younger than 18 years old.
Taking Trintellix in the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, serious lung problems, or other complications in the baby. However, stopping the medicine may not be safe for you. Do not start or stop Trintellix without asking your doctor.
Ask a doctor if it is safe to breastfeed while using this medicine.
How should I take Trintellix?
Take Trintellix exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
You may take Trintellix with or without food.
You may have withdrawal symptoms if you stop using Trintellix suddenly. Ask your doctor before stopping the medicine.
Store at room temperature away from moisture and heat.
