You should not use  clopidogrel if you have any active bleeding such as a stomach ulcer or bleeding in the brain.
Clopidogrel increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, if you have blood in your urine, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds.
Do not stop taking clopidogrel without first talking to your doctor, even if you have signs of bleeding. Stopping clopidogrel may increase your risk of a heart attack or stroke.
Before taking this medicine
You should not use clopidogrel if you are allergic to it, or if you have:
any active bleeding; or
a stomach ulcer or bleeding in the brain (such as from a head injury).
Tell your doctor if you have ever had:
an ulcer in your stomach or intestines; or
a bleeding disorder or blood clotting disorder.
Clopidogrel may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body. Your doctor may perform a blood test to make sure clopidogrel is right for you.
This medicine is not expected to harm an unborn baby. However, taking clopidogrel within 1 week before childbirth can cause bleeding in the mother. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using this medicine.
How should I take clopidogrel?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use these medicines exactly as directed.
Clopidogrel can be taken with or without food.
Clopidogrel is sometimes taken together with aspirin. Take aspirin only if your doctor tells you to.
Clopidogrel keeps your blood from coagulating (clotting) and can make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have any bleeding that will not stop.
You may need to stop using clopidogrel for a short time before a surgery, medical procedure, or dental work. Any healthcare provider who treats you should know that you are taking clopidogrel.
Do not stop taking clopidogrel without first talking to your doctor, even if you have signs of bleeding. Stopping the medicine could increase your risk of a heart attack or stroke.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding.
