Administration
Administer only by sub-Q injection; do not administer IV.
Administer initial self-administered dose under supervision of a qualified clinician.
Several preparations of glatiramer acetate are commercially available (e.g., Copaxone, Glatopa and other generic preparations), and there are 2 available dosage strengths.    The 20-mg/mL injection is administered once daily and the 40-mg/mL injection is administered 3 times a week; the 2 dosage strengths are not interchangeable.
Sub-Q Administration
Commercially available prefilled syringes intended for single use only; discard unused portion.
Allow prefilled syringes to reach room temperature by removing from refrigerator about 20 minutes prior to use. 
Inject sub-Q into the arm, abdomen, hip, or thigh.  
To minimize risk of localized lipoatrophy and skin necrosis, follow proper injection technique and rotate injection areas and sites with each injection.  (See Lipoatrophy and Skin Necrosis under Cautions.)
Dosage
Available as glatiramer acetate; dosage expressed in terms of the salt.
Adults
Multiple Sclerosis
Sub-Q
Dosage recommendations differ based on dosage strength (20 or 40 mg/mL) used. Dosage strengths are not interchangeable.
If using the 20-mg/mL injection, recommended dosage is 20 mg once daily. 
If using the 40-mg/mL injection, recommended dosage is 40 mg 3 times a week (administer injections at least 48 hours apart).
Special Populations
No special population dosage recommendations at this time. 
 Detailed Glatiramer dosage information
