Usual Adult Dose for Soft Tissue Sarcoma:
-Normal Bilirubin and AST or ALT 2.5 Times the Upper Limit of Normal (ULN) or Less:
1.5 mg/m2 via IV infusion every 21 days (3 weeks)
-Serum Bilirubin Levels Above Institutional ULN:
No recommended dose.
Duration of Therapy: Until disease progression or unacceptable toxicity
Comments:
-Administer this drug over 24 hours through a central venous line using an infusion set with a 0.2 micron polyethersulfone (PES) in-line filter.
-Complete infusion within 30 hours of drug reconstitution.
-Administer dexamethasone 20 mg IV 30 minutes prior to each dose.
Use: Treatment of patients with unresectable or metastatic liposarcoma or leiomyosarcoma who received a prior anthracycline-containing regimen.
 Detailed Yondelis dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Yondelis injection.
What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
