Filgrastim can cause your spleen to become enlarged and it could rupture (tear). Call your doctor right away if you have sudden or severe pain in your left upper stomach spreading up to your shoulder.
Before taking this medicine
You should not use  filgrastim if you are allergic to filgrastim or pegfilgrastim, or to other medicines that contain the E. coli bacteria.
Tell your doctor if you have ever had:
sickle cell disorder;
kidney disease;
latex allergy; or
radiation treatment.
Tell your doctor if you are pregnant or breastfeeding.
