You should not use Kineret if you are allergic to medicines that contain E. coli bacteria proteins, or if you have an active infection.
Before using Kineret, tell your doctor if you have asthma, kidney disease, a latex allergy, a weak immune system, an active or chronic infection, or signs of infection such as fever, chills, or open sores on your skin.
Kineret can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Stop using this medicine and call your doctor right away if you have signs of infection such as: fever, chills, flu symptoms, mouth sores, weight loss, or feeling tired or short of breath.
You may have a higher risk of infection if you are also using adalimumab (Humira), certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), adalimumab (Humira), cancer medicines, steroids, or medicines to prevent organ transplant rejection.
Do not give Kineret to anyone under 18 years old without medical advic
Before taking this medicine
You should not use Kineret if you are allergic to anakinra or if you have:
an active infection; or
an allergy to any medicine that contains E. coli bacteria proteins.
To make sure Kineret is safe for you, tell your doctor if you have:
kidney disease;
an active or chronic infection;
fever, chills, or open sores on your skin;
a weak immune system (caused by disease or by using certain medicines):
asthma; or
tuberculosis.
Tell your doctor if you are pregnant or plan to become pregnant. Having rheumatoid arthritis or CAPS during pregnancy may increase the risk of premature birth or low birth weight. The benefit of treating rheumatoid arthritis or CAPS may outweigh any risks to the baby.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Do not give this medicine to a child without medical advice. Kineret is not approved to treat rheumatoid arthritis in anyone younger than 18 years old.
How should I use Kineret?
Use Kineret exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Kineret is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.
Kineret is given either once per day or once every other day. Follow your doctor's dosing instructions very carefully. Inject your dose at the same time of day when you use the medicine.
Your healthcare provider will show you where on your body to inject Kineret. Use a different place each time you give an injection. Each injection should be given at least 1 inch away from where you last injected the medicine.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
Do not shake the prefilled syringe or you may ruin the medicine.
Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.
Call your doctor if your arthritis symptoms do not improve, or if they get worse while using Kineret.
Anakinra affects your immune system. You may get infections more easily. You will need frequent medical tests while using Kineret and for several months after you stop using it.
Store in the refrigerator, do not freeze. Protect from light. Throw away any unused medicine after the expiration date on the label has passed.
Each prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
