Ask your doctor before using Advil if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.
Ask a doctor or pharmacist before using ibuprofen with any other medications, especially:
cyclosporine;
lithium;
methotrexate;
a blood thinner (warfarin, Coumadin, Jantoven);
heart or blood pressure medication, including a diuretic or "water pill"; or
steroid medicine (such as prednisone).
This list is not complete. Other drugs may interact with ibuprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Advil drug interactions (more detail)
