Get emergency medical help if you have signs of an allergic reaction to bicalutamide: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
breast pain or swelling;
sudden chest pain, wheezing, dry cough, feeling short of breath;
low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet;
liver problems - nausea, upper stomach pain, feeling tired, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), fever, chills;
high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or
(if you also take warfarin) unusual bruising or bleeding.
Common bicalutamide side effects may include:
anemia;
blood in your urine;
fever, chills, flu-like symptoms;
trouble breathing;
hot flashes;
pain in your back, pelvis, or stomach;
swelling in your arms, ankles, legs, or feet;
increased night-time urination;
weakness, dizziness; or
nausea, diarrhea, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Bicalutamide side effects (more detail)
