Get emergency medical help if you have signs of an allergic reaction to Sabril (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Taking vigabatrin can cause permanent vision loss. Tell your doctor right away about any changes in your vision. If a child is taking Sabril: Tell the doctor right away if the child shows signs of vision changes, such as bumping into things or being easily startled or surprised.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
increased or worsening seizures;
any change in your vision, no matter how mild;
unusual or involuntary eye movements;
severe drowsiness, fussiness, or feeding problems (in a baby taking vigabatrin);
numbness, tingling, or burning pain in your hands or feet;
weight gain with or without swelling;
signs of an ear infection - fever, ear pain or full feeling, trouble hearing, drainage from the ear, fussiness in a child; or
low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.
Some babies treated with Sabril have had abnormal brain changes seen on magnetic resonance imaging (MRI). It is not known if these changes are caused by vigabatrin or if they are harmful. Tell any doctor who treats your baby that the child is taking this medicine.
Common Sabril side effects may include:
blurred vision or other eye problems;
drowsiness, dizziness, feeling tired;
problems with walking or coordination;
tremors or shaking;
aggressive behavior;
confusion, problems with thinking or memory;
weight gain;
joint pain;
cold symptoms such as stuffy nose, sneezing, sore throat; or
(in babies) fussiness, ear infection, cough, breathing problems.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Sabril side effects (more detail)
