Serious drug interactions can occur when certain medicines are used together with colchicine. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Before taking this medicine
You should not use colchicine if you are allergic to it.
Some medicines can cause unwanted or dangerous effects when used with colchicine, especially if you have liver or kidney disease. Your doctor may need to change your treatment plan if you use any of the following drugs:
cyclosporine;
nefazodone;
tipranavir;
clarithromycin or telithromycin;
itraconazole or ketoconazole; or
HIV or AIDS medicine--atazanavir, darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, or saquinavir.
To make sure colchicine is safe for you, tell your doctor if you have:
liver disease;
kidney disease; or
if you take digoxin, or cholesterol-lowering medications.
It is not known whether  colchicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Colchicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
