You should not use Epidiolex if you are allergic to cannabidiol or sesame seed oil.
Cannabidiol can harm your liver. Your liver function may need to be checked before and during treatment.
Call your doctor at once if you have symptoms such as: nausea, vomiting, loss of appetite, right-sided upper stomach pain, tiredness, itching, dark urine, or yellowing of the skin or eyes.
Avoid driving or hazardous activity until you know how Epidiolex will affect you.
Some people have thoughts about suicide while taking Epidiolex. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Before taking this medicine
Epidiolex is not approved for use by anyone younger than 1 year old.
To make sure Epidiolex is safe for you, tell your doctor if you have ever had:
liver disease;
drug or alcohol addiction;
depression, a mood disorder; or
suicidal thoughts or actions.
Some people have thoughts about suicide while taking Epidiolex. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
It is not known whether cannabidiol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of cannabidiol on the baby.
It may not be safe to breast-feed while using Epidiolex. Ask your doctor about any risk.
How should I take Epidiolex?
Take Epidiolex exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Epidiolex is usually taken 2 times per day. Take the medicine at the same times each day.
You may take Epidiolex with or without food, but take it the same way each time.
Measure this medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Make sure the dosing syringe is completely dry before measuring your dose.
Epidiolex liquid may be given through a feeding tube that is not made of polyvinyl chloride (PVC).
Cannabidiol can harm your liver. Your liver function may need to be checked before and during treatment. You may need to stop taking Epidiolex based on the results.
Store at room temperature, away from moisture and heat. Do not refrigerate or freeze. Keep the bottle tightly closed and in an upright position when not in use.
Throw away any unused liquid 12 weeks after you first opened the bottle.
Epidiolex can affect a drug-screening test and you may test positive for cannabis (marijuana). Tell the laboratory staff that you use cannabidiol.
Do not stop using Epidiolex suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.
