Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Modafinil can cause skin reactions that may be severe enough to need treatment in a hospital. Stop taking this medicine and get emergency medical help if you have:
skin rash or hives, blisters or peeling;
mouth sores, trouble swallowing;
fever, shortness of breath;
swelling in your legs;
dark urine, jaundice (yellowing of the skin or eyes); or
swelling in your face, eyes, lips, tongue, or throat.
Stop using modafinil and call your doctor at once if you have:
depression, anxiety, suicidal thoughts or actions;
hallucinations, unusual thoughts or behavior, aggression, being more active or talkative than usual;
chest pain, trouble breathing, uneven heart beats; or
the first sign of any skin rash, no matter how minor you think it might be.
Common side effects may include:
headache, dizziness;
feeling nervous or anxious;
back pain;
nausea, diarrhea, upset stomach;
sleep problems (insomnia); or
stuffy nose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Modafinil side effects (more detail)
