Get emergency medical help if you have signs of an allergic reaction to Nexplanon: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
warmth, redness, swelling, or oozing where the implant was inserted;
severe pain or cramping in your pelvic area (may be only on one side);
signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
signs of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;
heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
increased blood pressure - severe headache, blurred vision, pounding in your neck or ears;
swelling in your hands, ankles, or feet;
jaundice (yellowing of the skin or eyes);
a breast lump; or
symptoms of depression - sleep problems, weakness, tired feeling, mood changes.
Common Nexplanon side effects may include:
pain where the implant was inserted;
changes in your menstrual periods;
vaginal itching or discharge;
acne, mood changes, weight gain;
breakthrough bleeding, menstrual cramps;
nausea, stomach pain;
breast pain;
headache, dizziness; or
flu-like symptoms, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Nexplanon side effects (more detail)
