Hydrochlorothiazide is a thiazide diuretic (water pill). Triamterene is a potassium-sparing diuretic.
Hydrochlorothiazide and triamterene is a combination medicine that is used to treat fluid retention (edema) and high blood pressure (hypertension).
 hydrochlorothiazide and triamterene is usually given to people in whom other diuretics have caused hypokalemia (low potassium levels in your blood).
Hydrochlorothiazide and triamterene may also be used for purposes not listed in this medication guide.
