Usual Adult Dose for Chronic Myelogenous Leukemia:
Initial Dose: 45 mg orally once a day
Comments: The optimal dose has not been identified. The starting dose in clinical trials was 45 mg once a day; however, 68% of phase 2 trial patients required dose reductions to 30 mg or 15 mg once a day.
Uses: Treatment of:
-Chronic phase (CP), accelerated phase (AP), or blast phase (BP) chronic myeloid leukemia (CML) or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) for whom no other tyrosine kinase inhibitor (TKI) therapy is indicated.
-T315I-positive CP/AP/BP CML or T315I-Ph+ ALL
 Detailed Iclusig dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
