You should not use Nayzilam if you have narrow-angle glaucoma.
MISUSE OF NAYZILAM CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.
Nayzilam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, if you are hard to wake up, or if you stop breathing.
Do not stop using Nayzilam suddenly, or you could have dangerous withdrawal symptoms that could last for several weeks to months.
Some people have thoughts about suicide while using Nayzilam. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Before taking this medicine
You should not use Nayzilam nasal spray if you are allergic to midazolam, or if you have:
narrow-angle glaucoma.
To make sure Nayzilam is safe for you, tell your doctor if you have ever had:
open-angle glaucoma;
depression, or a mood disorder;
suicidal thoughts or actions;
liver or kidney disease;
asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
congestive heart failure;
drug or alcohol addiction; or
if you use opioid medicine.
Some people have thoughts about suicide while using seizure medicine. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Tell your doctor if you are pregnant or plan to become pregnant. Your name may be listed on a pregnancy registry to track the effects of midazolam on the baby.
If you use Nayzilam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.
Using Nayzilam nasal spray right before childbirth may cause breathing problems, feeding problems, or dangerously low body temperature in the newborn baby.
It may not be safe to breastfeed while using Nayzilam. Ask your doctor about any risk.
How should I use Nayzilam nasal spray?
Use Nayzilam exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Midazolam may be habit-forming. Misuse can cause addiction, overdose, or death. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Do not take by mouth. This medicine is for use only in the nose.
Before using Nayzilam nasal spray, be sure you know how to recognize what is and is not a seizure cluster and when it is best to use this medicine. Ask your doctor or pharmacist if you have questions.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Nayzilam nasal spray is usually given as a single spray into one nostril. If you still have seizures 10 minutes after using 1 spray, use a second spray in the opposite nostril.
Get emergency medical help if you have still have seizures after using Nayzilam.
You should not use a second spray if you have very slow breathing after using the first spray.
Do not use more than 2 sprays of Nayzilam nasal spray to treat a seizure cluster. Do not use this medicine to treat more than 1 seizure cluster every 3 days, or more than 5 seizure clusters in one month (30 days).
Do not stop using this medicine suddenly, or you could have dangerous withdrawal symptoms. Follow your doctor's instructions about tapering your dose.
Store at room temperature away from moisture and heat. Keep the spray bottle in the blister pack until you are ready to use the medicine.
