Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Stop taking  Jentadueto XR and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.
Mild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, fast/slow or irregular heartbeats, dizziness, feeling cold, or feeling very weak or tired.
Call your doctor at once if you have:
a severe autoimmune reaction--itching, blisters, breakdown of the outer layer of skin;
severe or ongoing pain in your joints; or
symptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.
Common side effects may include:
sore throat;
sinus pain, stuffy nose; or
diarrhea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Jentadueto XR side effects (more detail)
