Afinitor can cause serious and sometimes fatal side effects. Call your doctor right away if you have: signs of infection--fever, chills, skin rash, joint pain, tiredness; lung problems--cough, chest pain, wheezing, shortness of breath; kidney problems--swelling, little or no urination; or liver problems--loss of appetite, dark urine, yellowing of your skin or eyes, or upper stomach pain.
If you have ever had hepatitis B, Afinitor can cause this condition to come back or get worse.
You may be more likely to have an allergic reaction if you take an "ACE inhibitor" heart or blood pressure medication while you are taking Afinitor. Tell your doctor about all your current medicines and any you start or stop using.
Before taking this medicine, tell your doctor if you have a breathing disorder such as asthma or COPD, liver disease (or a history of hepatitis B), an active infection, diabetes or high blood sugar, or high cholesterol.
Do not use everolimus if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medicine and for at least 8 weeks after your treatment ends.
Before taking this medicine
You should not use Afinitor if you are allergic to everolimus, sirolimus (Rapamune), or temsirolimus (Torisel).
To make sure Afinitor is safe for you, tell your doctor if you have ever had:
an active or chronic infection;
liver disease, especially hepatitis B;
kidney disease;
diabetes or high blood sugar;
high cholesterol;
if you are scheduled to receive any vaccine; or
high blood pressure.
Afinitor can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
If you are a woman, do not use Afinitor if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 8 weeks after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 weeks after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Afinitor.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because Afinitor can harm an unborn baby.
You should not breastfeed while using this medicine and for at least 2 weeks after your last dose.
