Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor if you take any of the following medication, as these drugs may affect Lamictal;
anti-epileptic medications including valproic acid, divalproex sodium, carbamazepine, phenytoin, phenobarbital, or primidone;
antibiotics, such as rifampin;
birth control pills called oral contraceptives; or
human immunodeficiency virus (HIV) medications including lopinavir/ritonavir or atazanavir/lopinavir
Other drugs may interact with lamotrigine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
 Lamictal drug interactions (more detail)
