What do the results mean?If your estradiol or estrone levels are higher than normal, it may be due to:A tumor of the ovaries, adrenal glands, or testiclesCirrhosisEarly puberty in girls; delayed puberty in boysIf your estradiol or estrone levels are lower than normal, it may be due to:Primary ovarian insufficiency, a condition that causes a woman's ovaries to stop working before she is 40 years oldTurner syndrome, a condition in which a woman's sexual characteristics don't develop properlyAn eating disorder, such as anorexia nervosaPolycystic ovary syndrome, a common hormone disorder affecting childbearing women. It is one of the leading causes of female infertility.If you are pregnant and your estriol levels are lower than normal, it may mean your pregnancy is failing or that there is a chance your baby might have a birth defect. If the test shows a possible birth defect, you will need more testing before a diagnosis can be made.Higher levels of estriol may mean you will be going into labor soon. Normally, estriol levels go up about four weeks before you start labor.If you have questions about your results, talk to your health care provider.Learn more about laboratory tests, reference ranges, and understanding results.
