You should not use trazodone if you are allergic to it, or if you are being treated with methylene blue injection.
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, tranylcypromine and others.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using trazodone. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. Trazodone is not approved for use in children.
Before taking this medicine
You should not use trazodone if you are allergic to it.
Do not use trazodone if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
After you stop taking trazodone, you must wait at least 14 days before you start taking an MAOI.
Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with trazodone could cause a serious condition called serotonin syndrome.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
liver or kidney disease;
heart disease, or a recent heart attack;
a bleeding or blood clotting disorder;
seizures or epilepsy;
narrow-angle glaucoma;
long QT syndrome;
drug addiction or suicidal thoughts; or
bipolar disorder (manic depression).
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Taking trazodone during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop trazodone without asking your doctor.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of trazodone on the baby.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Trazodone is not approved for use by anyone younger than 18 years old.
