Many drugs can interact with metformin and sitagliptin. Some drugs can affect how well Janumet controls your blood sugar. Other drugs may increase your risk of lactic acidosis.
Tell your doctor if you use any of the following medications before taking Janumet:
anti-seizure medications (including topiramate, zonisamide, acetazolamide, phenytoin, and others)
anti-viral medications for HIV or AIDS;
antipsychotic medications (especially chlorpromazine, prochlorperazine, thioridazine, and others);
dichlorphenamide;
antacid medications including cimetidine;
ranolazine;
vandetanib;
corticosteroid medications (such as prednisone),
estrogen-containing medications including birth control pills or hormone replacement;
heart or blood pressure medications (especially digoxin, diuretics or water pills, calcium channel blockers, and others); or
other diabetes medications including insulin, sulfonylureas, or others
Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using. Give a list of all your medicines to any healthcare provider who treats you.
Date modified:
 Janumet drug interactions (more detail)
