Get emergency medical help if you have signs of an allergic reaction to Sutent (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Sunitinib can cause severe or fatal effects on your liver. Call your doctor if you have loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Sutent may also cause life-threatening blood clots in the small blood vessels inside your organs, such as your brain or kidneys. Seek medical help right away if you have symptoms of this condition, such as a fever, tiredness, decreased urination, bruising, or nosebleeds.
Also call your doctor at once if you have:
pain, redness, numbness, and peeling skin on your hands or feet;
easy bruising, unusual bleeding, purple or red spots under your skin;
painful skin sores, sores in your mouth or on your lips;
jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work;
confusion, thinking problems, vision loss, seizure;
heart problems - swelling, rapid weight gain, fast or pounding heartbeats, fluttering in your chest, shortness of breath, sudden dizziness (like you might pass out);
increased blood pressure - severe headache, blurred vision, pounding in your neck or ears, dizziness;
low blood sugar - headache, hunger, weakness, sweating, fast heart rate, feeling jittery;
signs of bleeding inside your body - change in your mental state, blood in your urine, pain and swelling in your stomach, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
signs of tumor cell breakdown - tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, tingling in your hands and feet or around your mouth; or
symptoms of a thyroid problem - severe and worsening tiredness, depression, fast heart rate, agitation, tremors, feeling nervous, sweating, nausea, vomiting, diarrhea, hair loss, weight changes, irregular menstrual periods.
Common Sutent side effects may include:
indigestion, decreased appetite, stomach pain, nausea, vomiting, diarrhea;
feeling weak or tired;
mouth sores or pain, altered sense of taste;
blisters or rash on your hands or feet;
bruising or bleeding; or
increased blood pressure.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Sutent side effects (more detail)
