Get emergency medical help if you have signs of an allergic reaction to Votrient: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor or get emergency medical help if you have signs of dangerously high blood pressure: severe chest pain, severe headache, blurred vision, pounding in your neck or ears, anxiety, shortness of breath, or feeling like you might pass out.
Call your doctor at once if you have:
headache, confusion, change in mental status, vision changes, seizure;
sudden chest pain, wheezing, dry cough;
unusual bleeding or bruising;
any wound or surgical incision that will not heal;
fast or pounding heartbeats, fluttering in your chest, and sudden dizziness (like you might pass out);
heart problems - swelling, rapid weight gain, feeling short of breath;
liver problems - nausea, vomiting, upper stomach pain, loss of appetite, tiredness, dark urine, or jaundice (yellowing of the skin or eyes).
signs of infection - fever, runny nose, sore throat, body aches, skin sores, pain or burning when you urinate;
signs of stomach bleeding - stomach pain or swelling, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
signs of a stroke or blood clot - sudden numbness or weakness, severe headache, slurred speech, vision problems, chest pain, sudden shortness of breath, pain or cold feeling in an arm or leg; or
signs of tumor cell breakdown - tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, tingling in your hands and feet or around your mouth.
Liver problems may be more likely in adults older than 65.
Common Votrient side effects may include:
nausea, vomiting, diarrhea, stomach pain;
loss of appetite, weight loss;
trouble breathing;
tumor pain, bone pain, muscle pain;
headache, feeling tired;
changes in hair or skin color; or
changes in your sense of taste.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Votrient side effects (more detail)
