Get emergency medical help if you have signs of an allergic reaction to Xultophy: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
severe nausea and vomiting;
shortness of breath (even with mild exertion);
swelling in your feet or ankles, rapid weight gain;
signs of pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
kidney problems - little or no urination, painful or difficult urination; or
low potassium level - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.
Common Xultophy side effects include:
nausea, diarrhea;
headache; or
cold symptoms such as stuffy or runny nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Xultophy side effects (more detail)
