Usual Adult Dose for Seizures:
16 years of age and older:-Initial dose: 100 mg orally once a day-Titration: After 2 weeks at 100 mg/day, the dose may be increased to 200 mg/day as either a single or divided dose (100 mg orally 2 times a day) for at least 2 weeks; it can then be increased to 300 mg/day, then 400 mg/day either as a single daily dose or divided into 2 daily doses, with the dose stable for at least 2 weeks to achieve steady state at each level -Maintenance dose: 400 mg/day-Maximum dose: 600 mg/day Comments:-This drug may be taken with or without food.-Capsules should be swallowed whole.-Because of the long half-life of this drug, up to 2 weeks may be required to achieve steady state levels upon reaching a stable dose or following dosage adjustment.-The prescriber may wish to prolong the duration of treatment at the lower doses in order to fully assess the effects of this drug at steady state (noting that many of the side effects are more frequent at doses of 300 mg per day and above).  Although there is some evidence of greater response at doses above 100 to 200 mg/day, the increase appears small and formal dose response studies have not been conducted.Use: As adjunctive therapy in the treatment of partial seizures
Usual Pediatric Dose for Seizures:
Less than 16 years of age: Not recommended16 years of age and older: See adult dosing
 Detailed Zonisamide dosage information
