Ask a doctor or pharmacist before using oxymetazoline with any other medications, especially:
heart or blood pressure medicine;
a beta blocker--atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others; or
an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
This list is not complete. Other drugs may affect oxymetazoline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
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