Get emergency medical help if you have signs of an allergic reaction to Afinitor: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have some of these symptoms if you also take an "ACE inhibitor" heart or blood pressure medication.
Call your doctor at once if you have:
blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
lung problems - new or worsening cough, chest pain, wheezing, feeling short of breath;
signs of infection - fever, chills, tiredness, joint pain, skin rash;
kidney problems - little or no urination; swelling in your feet or ankles;
liver problems - nausea, loss of appetite, stomach pain (upper right side), dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
low blood cell counts - flu-like symptoms, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed;
any wound that will not heal; or
a surgical incision that is red, warm, swollen, painful, bleeding, or oozing pus.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Afinitor side effects may include:
fever, cough, infections, feeling weak or tired;
mouth sores;
nausea, loss of appetite;
swelling anywhere in your body;
rash;
missed menstrual periods;
headache; or
high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Afinitor side effects (more detail)
