Get emergency medical help if you have signs of an allergic reaction: hives, sweating; dizziness, fast heart rate; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.
Filgrastim can cause your spleen to become enlarged and it could rupture (tear). Call your doctor right away if you have sudden or severe pain in your left upper stomach spreading up to your shoulder.
Stop using filgrastim and call your doctor at once if you have:
fever, tiredness, stomach pain, back pain;
rapid breathing, feeling short of breath, pain while breathing;
capillary leak syndrome--sudden dizziness or light-headed feeling, tiredness, trouble breathing, swelling or puffiness and feeling full;
kidney problems--little or no urinating, blood in your urine, swelling in your face or ankles;
low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or
signs of infection--fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, unusual weakness.
Common side effects may include:
fever, cough, trouble breathing;
nosebleeds;
bone pain, muscle or joint pain;
diarrhea;
headache;
numbness; or
rash, thinning hair.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Filgrastim side effects (more detail)
