Hizentra can cause severe allergic reactions, kidney failure, liver problems, or blood clots. The risk of blood clots is highest in older adults or in people who have had blood clots, heart problems, or blood circulation problems. Blood clots are also more likely during long-term bedrest, while using birth control pills or hormone replacement therapy, or while having a central intravenous (IV) catheter in place.
Call your doctor at once if you have chest pain, trouble breathing, fast heartbeats, numbness or weakness, or swelling and warmth or discoloration in an arm or leg.
This medicine can also harm your kidneys, especially if you have kidney disease or if you also use certain medicines. Tell your doctor right away if you have signs of kidney problems, such as swelling, rapid weight gain, and little or no urination.
Drink plenty of liquids while you are using Hizentra to help improve your blood flow and keep your kidneys working properly.
You should not use Hizentra if you have a condition called hyperprolinemia (high level of a certain amino acid in the blood).
Before using this medicine
You should not use Hizentra if:
you have had an allergic reaction to an immune globulin or blood product; or
you have immune globulin A (IgA) deficiency with antibody to IgA.
You may not be able to use Hizentra if you have ever had an allergic reaction to polysorbate 80, or if you have a condition called hyperprolinemia (high level of a certain amino acid in the blood).
This medicine can cause blood clots or kidney problems, especially in older adults or in people with certain conditions. To make sure Hizentra injection is safe for you, tell your doctor if you have ever had:
heart problems, blood circulation problems, or "thick blood";
a stroke or blood clot;
kidney disease;
diabetes;
an infection called sepsis;
if you use estrogens (birth control pills or hormone replacement therapy);
if you have been on long-term bedrest; or
if you have a central intravenous (IV) catheter in place.
You may need a dose adjustment if you are exposed to measles, or if you
Do not give this medicine to a child without medical advice.
Hizentra is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
