Usual Adult Dose for Hyperphosphatemia of Renal Failure:
Initial Dosing for patients not on a phosphate binder: 800 mg to 1600 mg orally 3 times a day with meals.
Based on serum phosphorus level:
-Phosphorus greater than 5.5 to less than 7.5 mg/dL: 800 mg 3 times a day with meals
-Phosphorus greater than or equal to 7.5 to less than 9 mg/dL: 1200 to 1600 mg 3 times a day with meals
-Phosphorus greater than or equal to 9 mg/dL: 1600 mg 3 times a day with meals
-Titrate in increments of 800 mg 3 times a day at 2-week intervals with the goal of controlling serum phosphorus within target range.
Average prescribed dose: 7.2 g/day (2.4 g with each meal)
Maximum studied dose: 14 g per day (carbonate); 13 g per day (hydrochloride)
Switching from the hydrochloride salt to carbonate: Use the same dose, however further titration may be necessary to achieve desired phosphorus levels.
Switching from calcium acetate: Substitute approximately mg for mg
Comment: Treatment of hyperphosphatemia includes reduction in dietary intake of phosphate, inhibition of intestinal phosphate absorption with phosphate binders, and removal of phosphate with dialysis.
Use: To control serum phosphorus levels in patients with chronic kidney disease on dialysis.
 Detailed Renvela dosage information
What happens if I miss a dose?
Take the missed dose as soon as you remember. Be sure to take the missed dose with food. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
