Get emergency medical help if you have signs of an allergic reaction to glyburide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Call your doctor at once if you have:
dark urine, jaundice (yellowing of the skin or eyes);
severe skin rash, redness, or itching;
pale skin, easy bruising or bleeding;
fever, chills, sore throat, mouth sores; or
low levels of sodium in the bodyheadache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.
Older adults may be more likely to have low blood sugar while taking glyburide.
Common glyburide side effects may include:
low blood sugar;
nausea, heartburn, feeling full;
muscle or joint pain;
blurred vision; or
mild rash or skin redness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Glyburide side effects (more detail)
