Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Tresiba is injected under the skin, usually once daily at any time of day. A healthcare provider will teach you how to properly use the medication by yourself.
Tresiba must not be given with an insulin pump, or mixed with other insulins. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
A dose counter on the injection pen shows your dose in units. Do not convert your dose. Use the U-100 vial for a child whose dose is less than 5 units per day.
Do not inject  Tresiba into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.
Never share an injection pen with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.
You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda). Be sure you know how to use a glucagon injection kit if your doctor prescribes one.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
Tresiba is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen. Keep vials in their original container protected from heat and light.
Storing unopened (not in use) Tresiba:
Refrigerate and use until expiration date; or
Store at room temperature and use within 8 weeks (56 days).
Storing opened (in use) Tresiba:
Refrigerate or store at room temperature and use within 8 weeks. Do not store the injection pen with a needle attached.
Do not use the medicine if it looks cloudy or has changed colors. Call your pharmacist for new medicine.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
 Detailed Tresiba dosage information
What happens if I miss a dose?
Use the missed dose as soon as you remember. Then continue your regular dosing schedule, allowing at least 8 hours to pass between doses. Do not use two doses at one time.
Call your doctor for instructions if a child misses a dose.
Keep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Insulin overdose can cause life-threatening hypoglycemia. Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure (convulsions), or loss of consciousness.
