Get emergency medical help if you have signs of an allergic reaction to Xeloda (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Diarrhea may occur and could be severe. Stop taking Xeloda and tell your doctor right away if the number of bowel movements you usually have per day increases by 4 or more, or if you have bowel movements at night.
Stop using Xeloda and call your doctor at once if you have:
severe diarrhea;
bloody diarrhea with severe stomach pain and fever;
severe nausea or loss of appetite that causes you to eat much less than usual;
vomiting (more than once in 24 hours);
fever above 100.5 degrees;
sores or ulcers in your mouth, redness or swelling of your mouth or tongue, trouble eating or swallowing;
jaundice (yellowing of the skin or eyes);
dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
"hand and foot syndrome" - pain, tenderness, redness, swelling, blistering, or peeling skin on your hands or feet;
heart problems - chest pain, irregular heartbeats, swelling in your lower legs, rapid weight gain, feeling lightheaded or short of breath; or
low blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Xeloda side effects may include:
nausea, vomiting, diarrhea, stomach pain;
feeling weak or tired;
hand and foot syndrome; or
jaundice.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Xeloda side effects (more detail)
