Using baclofen with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death.
Tell your physician if you are taking any of the following medications:
Opioid medications
Sleeping pills
Muscle relaxers
Medication for depression, anxiety, or bipolar disorder
Seizure medication
Blood pressure medication
Other drugs may interact with baclofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
 Baclofen drug interactions (more detail)
