MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.
Taking  buprenorphine and naloxone during pregnancy may cause life-threatening withdrawal symptoms in the newborn.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
Before taking this medicine
You should not use this medicine if you are allergic to buprenorphine or naloxone (Narcan).
Tell your doctor if you have ever had:
breathing problems, sleep apnea;
enlarged prostate, urination problems;
liver or kidney disease;
abnormal curvature of the spine that affects breathing;
problems with your gallbladder, adrenal gland, or thyroid;
a head injury, brain tumor, or seizures; or
alcoholism or drug addiction.
If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.
Ask a doctor before using opioid medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
