Omeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.
Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.
Omeprazole is not to used for the immediate relief of heartburn symptoms.
Omeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.
You may be more likely to have a broken bone while taking this medicine long term or more than once per day.
Before taking this medicine
Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel sweaty or light-headed.
You should not use omeprazole if you are allergic to it, or if:
you are also allergic to medicines like omeprazole, such as esomeprazole, lansoprazole, pantoprazole, rabeprazole, Nexium, Prevacid, Protonix, and others;
you had breathing problems, kidney problems, or a severe allergic reaction after taking omeprazole in the past; or
you also take HIV medication that contains rilpivirine (such as Complera, Edurant, Odefsey, Juluca).
Ask a doctor or pharmacist if this medicine is safe to use if you have:
trouble or pain with swallowing;
bloody or black stools, vomit that looks like blood or coffee grounds;
heartburn that has lasted for over 3 months;
frequent chest pain, heartburn with wheezing;
unexplained weight loss;
nausea or vomiting, stomach pain;
liver disease;
low levels of magnesium in your blood; or
osteoporosis or low bone mineral density (osteopenia).
You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.
Ask a doctor before using this medicine if you are pregnant or breastfeeding.
Do not give this medicine to a child without medical advice.
