Usual Adult Dose for Constipation -- Chronic:
24 mcg orally 2 times a day
Comments: The effectiveness of this drug in the treatment of opioid-induced constipation in patients taking diphenylheptane opioids (e.g., methadone) has not been established.
Use: Treatment of chronic idiopathic constipation and of opioid-induced constipation in adults with chronic non-cancer pain.
Usual Adult Dose for Irritable Bowel Syndrome:
8 mcg orally 2 times a day
Use: Treatment of irritable bowel syndrome with constipation (IBS-C) in women age 18 years and older.
 Detailed Amitiza dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
