Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Abnormal heart sound
absence of or decrease in body movement
arm, back, or jaw pain
black, tarry stools
bladder pain
bleeding after defecation
bleeding gums
blood in the urine or stools
blurred vision
body aches or pain
burning while urinating
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or discomfort
chest tightness or heaviness
chills
cold sweats
colds
confusion
convulsions
cough or hoarseness
decreased urine
diarrhea
difficult or labored breathing
difficult, burning, or painful urination
dilated neck veins
dizziness
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
dry mouth
ear congestion
extra heartbeats
fainting
fast, slow, irregular, pounding, or racing heartbeat or pulse
fever or chills
flu-like symptoms
frequent urge to urinate
frequent urination
general feeling of discomfort or illness
headache
headache, severe and throbbing
heart murmur
increased need to urinate
increased sweating
increased thirst
increased volume of pale, dilute urine
irregular breathing
itching, pain, redness, or swelling on the leg
joint pain, stiffness, or swelling
lightheadedness
loss of appetite
loss of voice
lower back, side, or stomach pain
muscle aches and pains
muscle cramps
nasal congestion
nausea or vomiting
nervousness
numbness or tingling in the hands, feet, or lips
pain or discomfort in the arms, jaw, back, or neck
pain, tension, and weakness upon walking that subsides during periods of rest
partial or slight paralysis
passing urine more often
pinpoint red or purple spots on the skin
pounding in the ears
runny nose
shakiness in the legs, arms, hands, or feet
shivering
sneezing
sore on the leg
sore throat
sudden decrease in the amount of urine
sweating
swelling
swelling of the face, fingers, feet, or lower legs
tightness in the chest
trembling or shaking of the hands or feet
trouble sleeping
troubled breathing
uncomfortable swelling around the anus
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds
weakness
weight gain
Rare
Bluish-colored lips, fingernails, or palms
dark urine
pale skin
rapid heart rate
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Blurred or loss of vision
bulging soft spot on the head of an infant
change in consciousness
change in the ability to see colors, especially blue or yellow
cold, clammy skin
disturbed color perception
double vision
feeling of constant movement of self or surroundings
halos around lights
headache, severe and throbbing
loss of consciousness
night blindness
overbright appearance of lights
paralysis
sensation of spinning
tunnel vision
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Acid or sour stomach
anxiety
back pain
belching
blemishes on the skin
bloated
breast pain
burning feeling in the chest or stomach
burning, dry, or itching eyes
change in color vision
changes in vision
cold sweats
congestion
constipation
continuing ringing or buzzing or other unexplained noise in the ears
cough producing mucus
decreased interest in sexual intercourse
difficulty seeing at night
difficulty with moving
discharge, excessive tearing
double vision
drooping upper eyelids
dull ache or feeling of pressure or heaviness in the legs
earache
excess air or gas in the stomach or intestines
feeling of constant movement of self or surroundings
feeling of warmth
feeling unusually cold
frequent urge to defecate
frozen shoulder
full feeling
hearing loss
heartburn
hyperventilation
inability to have or keep an erection
increased appetite
increased sensitivity of the eyes to sunlight
increased sputum
indigestion
irritability
itching skin near damaged veins
lack or loss of strength
loss in sexual ability, desire, drive, or performance
muscle or bone pain
muscle stiffness or weakness
nightmares
noisy breathing
pain or tenderness around the eyes and cheekbones
passing gas
pimples
poor concentration
rash
redness of the face, neck, arms, and occasionally, upper chest
redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
redness, swelling, or soreness of the tongue
restlessness
seeing double
sensation of spinning
sleepiness or unusual drowsiness
small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope
small lumps under the skin
sore mouth or tongue
stiff neck
stomach bloating, burning, cramping, or pain
stomach discomfort or upset
straining while passing stool
stuffy nose
sudden sweating
swollen feet and ankles
tender, swollen glands in the neck
tenderness in the stomach area
terrifying dreams causing sleep disturbances
tooth disorder
trouble swallowing
uncontrolled twisting movements of the neck
voice changes
weight loss
white patches in the mouth, tongue, or throat
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
 Isosorbide mononitrate side effects (more detail)
