Usual Adult Dose for Schizophrenia:
Oral:Initial dose: 20 mg orally twice a dayMaintenance dose: Adjust as clinically indicated at intervals of not less than 2 daysMaximum dose: 100 mg twice a dayComments: A dose greater than 80 mg twice a day is generally not recommended.  Intramuscular: Recommended dose: 10 to 20 mg IM; may repeat 10 mg IM every 2 hours or 20 mg IM every 4 hours up to maximum daily doseMaximum dose: 40 mg IM per dayDuration of therapy: Use beyond 3 consecutive days has not been studied Comments: -Coadministration of IM ziprasidone to patient's already taking oral ziprasidone has not been studied and is not recommended.  -If long-term therapy is indicated, oral capsules should replace IM administration as soon as possible.  Uses: -Treatment of schizophrenia (oral)-Acute treatment of agitation in schizophrenia (IM)
Usual Adult Dose for Bipolar Disorder:
Acute Treatment of Manic or Mixed Episodes: -Initial dose: 40 mg orally twice daily-Increase dose to 60 mg or 80 mg twice daily on the second day; subsequently adjust dose based on tolerance and efficacy within the dose range of 40 to 80 mg orally twice a dayMaintenance Treatment (as adjunct to lithium or valproate):-Once stabilized, continue on same dose within the range of 40 to 80 mg orally twice daily.  Comments: -The mean ziprasidone dose administered in flexible-dose clinical trials was approximately 120 mg per day.  -Monotherapy has not been systematically evaluated for maintenance treatment of bipolar I disorder.Uses: -As monotherapy for the acute management of manic or mixed episodes associated with bipolar I disorder-As adjunct to lithium or valproate for the maintenance treatment of bipolar I disorder.
 Detailed Ziprasidone dosage information
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