Ofloxacin can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.
Stop using  ofloxacin and call your doctor at once if you have symptoms such as: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints.
In rare cases, ofloxacin may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.
Before taking this medicine
You should not use this medicine if you are allergic to ofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, and others).
Ofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking ofloxacin. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).
Tell your doctor if you have ever had:
tendon problems, bone problems, arthritis, or other joint problems;
blood circulation problems, aneurysm, narrowing or hardening of the arteries;
heart problems, high blood pressure;
a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome;
diabetes;
a muscle or nerve disorder, such as myasthenia gravis;
liver or kidney disease;
a seizure;
long QT syndrome (in you or a family member); or
low levels of potassium in your blood (hypokalemia).
Ofloxacin is not approved for use by anyone younger than 18 years old.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
You should not breast-feed while using this medicine.
