Usual Adult Dose for Irritable Bowel Syndrome:
290 mcg orally once a day
Comments:
-Patients should take this drug on an empty stomach, at least 30 minutes prior to the first meal of the day.
-Capsules should be swallowed whole; patients should avoid breaking apart or chewing the capsules.
-Patients with swallowing difficulties may open the capsules and administer orally (in applesauce or water) OR via nasogastric or gastrostomy tube (in water).
Use: Treatment of irritable bowel syndrome with constipation (IBS-C)
Usual Adult Dose for Constipation:
145 mcg orally once a day
Comments:
-Some patients may be given 72 mcg orally once a day based on individual characteristics and tolerability.
-Patients should take this drug on an empty stomach, at least 30 minutes prior to the first meal of the day.
-Capsules should be swallowed whole; patients should avoid breaking apart or chewing the capsules.
-Patients with swallowing difficulties may open the capsules and administer orally (in applesauce or water) OR via nasogastric or gastrostomy tube (in water).
Use: Treatment of chronic idiopathic constipation (CIC)
 Detailed Linzess dosage information
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
