Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
a seizure;
an unusual mass or lump;
severe vomiting or diarrhea;
new or worsening cough;
bone marrow suppression--dizziness, pale lips or fingernail beds, fast heart rate, getting easily tired or short of breath;
liver problems--loss of appetite, stomach pain (upper right side), dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.
Common side effects may include:
bone marrow suppression;
low blood cell counts;
missed menstrual periods;
nausea, vomiting, diarrhea; or
sores or white patches in or around your mouth.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Leukeran side effects (more detail)
