Usual Adult Dose for Multiple Myeloma:
In combination with dexamethasone:
25 mg orally once a day on Days 1 to 21 of repeated 28-day cycles until disease progression or unacceptable toxicity
Maintenance therapy following auto-HSCT:
10 mg once a day continuously (Days 1 to 28 of repeated 28-day cycles) for 3 cycles, then increase to 15 mg once a day if tolerated until disease progression or unacceptable toxicity
Comments:
-For patients who are not eligible for auto-HSCT, therapy should continue until disease progression or unacceptable toxicity.
-For patients who are eligible for auto-HSCT, hematopoietic stem cell mobilization should occur within 4 cycles.
-Following auto-HSCT, initiate maintenance therapy after adequate hematologic recovery (ANC 1000/mcL or more AND/OR platelet count 75,000/mcL or more).
-Consult the manufacturer product information for dexamethasone dosing recommendations.
Uses:
-In combination with dexamethasone for multiple myeloma (MM)
-Maintenance therapy in patients with MM following autologous hematopoietic stem cell transplantation (auto-HSCT)
Usual Adult Dose for Myelodysplastic Disease:
10 mg orally once a day; therapy is continued or modified based upon clinical and laboratory findings until disease progression or unacceptable toxicity
Use: Treatment of transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities
Usual Adult Dose for Lymphoma:
FOLLICULAR LYMPHOMA OR MARGINAL ZONE LYMPHOMA:
20 mg orally once a day on Days 1 through 21 of repeated 28-day cycles for up to 12 cycles in combination with a rituximab-product
MANTLE CELL LYMPHOMA:
25 mg orally once a day on Days 1 to 21 of repeated 28-day cycles until disease progression or unacceptable toxicity; treatment is continued, modified, or discontinued based upon clinical and laboratory findings
Uses:
-For the treatment of patients with mantle cell lymphoma (MCL) whose disease has relapsed or progressed after 2 prior therapies, onw1 of which included bortezomib
Use: In combination with a rituximab product for the treatment of previously treated follicular lymphoma (FL)
-In combination with a rituximab product for the treatment of previously treated marginal zone lymphoma (MZL)
 Detailed Revlimid dosage information
What happens if I miss a dose?
Take the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
