Avoid sources of heat while you are wearing the patch. Do not use a heating pad or electric blanket, a waterbed heater, tanning bed or sauna. Do not sit in hot water, sunbathe, or raise your body temperature with vigorous activity. Heat can increase the amount of drug you absorb through your skin and may cause an overdose or death.
Grapefruit may interact with fentanyl and lead to unwanted side effects. Avoid the use of grapefruit products.
Do not drink alcohol. Dangerous side effects or death could occur.
Avoid wearing a skin patch on a part of your body where a child could reach or remove the patch from your skin. Avoid allowing children to watch you put on a skin patch. Never tell a child that the fentanyl skin patch is a "bandage."
Avoid driving or operating machinery until you know how using fentanyl patches will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
