Taking hydrochlorothiazide with other drugs that make you light-headed can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
cholestyramine, colestipol;
insulin or oral diabetes medicine;
lithium;
other blood pressure medications;
steroid medicine; or
NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may affect hydrochlorothiazide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Hydrochlorothiazide drug interactions (more detail)
