Get emergency medical help if you have signs of an allergic reaction to Entyvio: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Vedolizumab may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Call your doctor at once if you have:
fever, chills, body aches, cold or flu symptoms, mouth and throat ulcers, skin sores;
pain, warmth, swelling, or oozing around your anal area;
nausea, vomiting, severe diarrhea, diarrhea that is watery or bloody, stomach cramps, weight loss;
cough, pain when swallowing; or
liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common Entyvio side effects may include:
fever, sore throat, flu symptoms;
cold symptoms such as stuffy nose, sinus pain, sneezing;
cough with mucus, shortness of breath, chest discomfort;
pain in your arms or legs;
tiredness;
headache, joint pain, back pain;
rash, itching; or
nausea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Entyvio side effects (more detail)
