Taking Juluca during the first trimester of pregnancy may cause birth defects. Use effective birth control to prevent pregnancy while you are using dolutegravir.
Before taking this medicine
You should not use Juluca if you are allergic to dolutegravir or rilpivirine.
Some medicines can cause unwanted or dangerous effects when used with Juluca. Your doctor may need to change your treatment plan if you also use:
dofetilide (can cause serious medical problems or death when taken with Juluca);
St John's wort;
more than one dose of dexamethasone;
carbamazepine, oxcarbazepine, phenobarbital, phenytoin;
rifampin, rifapentine; or
esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole.
To make sure Juluca is safe for you, tell your doctor if you have ever had:
liver problems;
mental illness;
a severe skin rash or allergic reaction to dolutegravir or rilpivirine; or
if you also take rifabutin.
You may need to have a negative pregnancy test before starting this treatment.
Juluca may harm an unborn baby if you take the medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
HIV can be passed to your baby if the virus is not controlled during pregnancy. If you are pregnant, your name may be listed on a registry to track any effects of antiviral medicine on the baby. Use your medications properly to control HIV.
Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
How should I take Juluca?
Take Juluca exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Always take this medicine with food, not with a meal replacement drink.
You will need frequent blood tests.
Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Get your prescription refilled before you run out of medicine completely.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with any packet or canister of moisture-absorbing preservative.
