You should not use dapagliflozin if you have diabetic ketoacidosis, severe kidney disease, or if you are on dialysis.
Taking dapagliflozin can make you dehydrated, which could cause you to feel weak or dizzy (especially when you stand up).
Dapagliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.
Before taking this medicine
You should not use dapagliflozin if you are allergic to it, or if you have:
severe kidney disease (or if you are on dialysis); or
diabetic ketoacidosis (call your doctor for treatment).
Tell your doctor if you have ever had:
liver or kidney disease;
bladder infections or other urination problems;
low blood pressure;
problems with your pancreas, including surgery;
if you are dehydrated;
if you drink alcohol often; or
if you are on a low salt diet.
Follow your doctor's instructions about using  dapagliflozin if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.
You should not use dapagliflozin during the second or third trimester of pregnancy.
You should not breast-feed while using this medicine.
Dapagliflozin is not approved for use by anyone younger than 18 years old.
How should I take dapagliflozin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take dapagliflozin with or without food.
Call your doctor if you are sick with vomiting or diarrhea, if you consume less food or fluid than usual, or if you are sweating more than usual.
Your blood sugar will need to be checked often, and you may also need to test the level of ketones your urine. Dapagliflozin can cause life-threatening ketoacidosis (too much acid in the blood). Even if your blood sugar is normal, contact your doctor if a urine test shows that you have ketones in the urine.
You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).
Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. You may need to stop taking dapagliflozin for at least 3 days before a surgery. Ask your doctor before changing your dose or medication schedule.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using dapagliflozin.
Dapagliflozin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
