Get emergency medical help if you have signs of an allergic reaction to Ortho Tri-Cyclen: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Ortho Tri-Cyclen and call your doctor at once if you have:
signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
signs of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;
heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
liver problems - loss of appetite, upper stomach pain, tiredness, fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
severe headache, pounding in your neck or ears;
swelling in your hands, ankles, or feet;
changes in the pattern or severity of migraine headaches;
a breast lump; or
symptoms of depression - sleep problems, weakness, tired feeling, mood changes.
Common Ortho Tri-Cyclen side effects may include:
stomach pain, gas, nausea, vomiting;
breast tenderness;
acne, darkening of facial skin;
headache, nervousness, mood changes;
qa
problems with contact lenses;
changes in weight;
breakthrough bleeding;
vaginal itching or discharge; or
rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Ortho Tri-Cyclen side effects (more detail)
