You should not use Rybelsus if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer, insulin-dependent diabetes, or diabetic ketoacidosis.
Call your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.
Before taking this medicine
You should not use Rybelsus if you are allergic to semaglutide, or if you have:
multiple endocrine neoplasia type 2 (tumors in your glands);
a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or
diabetic ketoacidosis (call your doctor for treatment).
To make sure Rybelsus is safe for you, tell your doctor if you have:
a stomach or intestinal disorder;
pancreatitis;
kidney disease; or
eye problems caused by diabetes (retinopathy).
In animal studies, semaglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.
Semaglutide may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Rybelsus can have long-lasting effects on your body. Avoid getting pregnant for at least 2 months after you stop using this medicine.
You should not breastfeed while using Rybelsus.
Rybelsus is not approved for use by anyone younger than 18 years old.
