Taking Geodon with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Geodon should never be taken together with any of the following drugs, or a life-threatening heart rhythm disorder could occur;
anagrelide;
methadone;
tacrolimus;
certain anti-nausea medicines including dolasetron, droperidol, or ondansetron;
the antibiotics azithromycin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, and pentamidine;
certain cancer medicines such as arsenic trioxide and vandetanib;
the antidepressants citalopram and escitalopram;
anti-malaria medications including chloroquine, halofantrine, mefloquine;
the following heart rhythm medicines - amiodarone, disopyramide, dofetilide, dronedarone, flecainide, ibutilide, quinidine, sotalol; or;
certain anti-psychotics such as chlorpromazine, haloperidol, mesoridazine, pimozide, and thioridazine;
Many other drugs can interact with ziprasidone. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Geodon. This includes prescription and over-the-counter medicines, vitamins, and herbal products.
 Geodon drug interactions (more detail)
