Anastrozole may decrease blood flow to your heart, especially if you have ever had coronary artery disease (clogged arteries). Seek medical attention if you have new or worsening chest pain, or if you feel short of breath.
Before taking this medicine
You should not use anastrozole if you are allergic to it, or if you have not yet completed menopause.
Anastrozole is not approved for use in men or children.
You should not take anastrozole if you also take tamoxifen.
Tell your doctor if you have ever had:
heart problems;
coronary artery disease (clogged artery disease);
high cholesterol; or
osteoporosis or low bone mineral density.
Hormonal cancer treatment can weaken your bones. You may be more likely to have a broken bone while using anastrozole. Talk with your doctor about ways to keep your bones healthy.
Although it is not likely that a postmenopausal woman would be pregnant, anastrozole may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of anastrozole. Tell your doctor if you become pregnant.
Do not breastfeed while using  anastrozole, and for at least 2 weeks after your last dose.
How should I take anastrozole?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Anastrozole is usually taken once per day. Follow your doctor's dosing instructions very carefully.
You may take anastrozole with or without food.
You may need to keep taking this medication for up to 5 years. Follow your doctor's instructions.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
