Nexletol may cause serious side effects, including:
increased levels of uric acid in your blood (hyperuricemia). This can happen within 4 weeks of you starting Nexletol and continue throughout your treatment. Your healthcare provider may monitor your blood uric acid levels while you are taking Nexletol. High levels of blood uric acid may lead to gout. Call your healthcare provider if you have the following symptoms of hyperuricemia and gout:
severe foot pain especially in the toe joint
warm joints
swelling
tender joints
joint redness
Gout may happen more in people who have had gout before but also can happen in people who have never had it before.
tendon rupture or injury. Tendon problems can happen in people who take Nexletol. Tendons are tough cords of tissue that connect muscles to bones. Symptoms of tendon problems may include pain, swelling, tears, and inflammation of tendons including the arm, shoulder, and back of the ankle (Achilles).
Tendon rupture can happen while you are taking Nexletol. Tendon ruptures can happen within days or months of starting Nexletol.
The risk of getting tendon problems while you take Nexletol is higher if you:
are over 60 years of age
are taking antibiotics (fluoroquinolones)
have had tendon problems
are taking steroids (corticosteroids)
have renal failure
Stop taking Nexletol immediately and get medical help right away if you get any of the following signs or symptoms of a tendon rupture:
hear or feel a snap or pop in a tendon area
bruising right after an injury in a tendon area
unable to move the affected area or put weight on the affected area
Stop taking Nexletol until tendon rupture has been ruled out by your healthcare provider. Avoid exercise and using the affected area. The most common areas of pain and swelling are the rotator cuff (the shoulder), the biceps tendon (upper arm), and Achilles tendon at the back of the ankle. This can happen with other tendons.
Talk to your healthcare provider about the risk of tendon rupture with continued use of Nexletol. You may need a different lipid-lowering medicine to treat your cholesterol levels.
 
The most common side effects of Nexletol include:
symptoms of the common cold, flu, or flu-like symptoms
back pain
stomach pain
increased liver enzymes
muscle spasms
pain in shoulder, legs, or arms
anemia
bronchitis
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Nexletol. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Nexletol side effects (more detail)
How should I store Nexletol?
Store Nexletol in the original package at room temperature between 68ºF to 77ºF (20ºC to
25ºC).
Do not throw away the packet that helps to keep your medicine dry (desiccant).
Keep Nexletol and all medicines out of the reach of children.
General information about the safe and effective use of Nexletol.
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Nexletol for a condition for which it was not prescribed. Do not give Nexletol to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about Nexletol that is written for healthcare professionals.
What are the ingredients in Nexletol?
Active Ingredient: bempedoic acid
Inactive Ingredients: colloidal silicon dioxide, hydroxyl propyl cellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate
tablet coating: partially hydrolyzed polyvinyl alcohol, polyethylene glycol, talc, and titanium dioxide
