Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with ubrogepant. Your doctor may change your treatment plan if you also use:
nefazodone;
an antibiotic--clarithromycin, telithromycin;
antifungal medicine--itraconazole, ketoconazole; or
antiviral medicine to treat HIV/AIDS--indinavir, nelfinavir, ritonavir, saquinavir.
Tell your doctor if you have ever had:
liver disease; or
kidney disease.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether ubrogepant will harm an unborn baby. However, having migraine headaches during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating migraines may outweigh any risks to the baby.
It may not be safe to breastfeed while using  ubrogepant. Ask your doctor about any risk.
Ubrogepant is not approved for use by anyone younger than 18 years old.
How should I take ubrogepant?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take ubrogepant with or without food. Avoid grapefruit or grapefruit juice.
After taking ubrogepant: If your headache does not completely go away, or goes away and comes back, you may take a second tablet if it has been at least 2 hours since your first dose. If your symptoms have not improved, contact your doctor before taking any more tablets.
You should not take a second tablet within 24 hours if you have consumed a grapefruit product, or if you also take any of the following medications:
ciprofloxacin;
cyclosporine;
fluconazole;
fluvoxamine; or
verapamil.
Call your doctor if you have more than 8 headaches in one month (30 days). Tell your doctor if this medicine seems to stop working as well in treating your migraine attacks.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Since ubrogepant is used when needed, it does not have a daily dosing schedule. Do not take more than 200 milligrams in a 24-hour period. Do not use ubrogepant to treat more than 8 headaches per month.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
