You should not use  hydrochlorothiazide and valsartan if you are unable to urinate, or if you are allergic to sulfa drugs.
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.
If you have diabetes, do not use hydrochlorothiazide and valsartan together with any medication that contains aliskiren (a blood pressure medicine).
Before taking this medicine
You should not use this medicine if you are allergic to valsartan or hydrochlorothiazide, or if you have:
decreased urination or are unable to urinate; or
an allergy to sulfa drugs.
If you have diabetes, do not use hydrochlorothiazide and valsartan together with any medication that contains aliskiren (a blood pressure medicine).
You may also need to avoid taking hydrochlorothiazide and valsartan with aliskiren if you have kidney disease.
Tell your doctor if you have ever had:
an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood);
liver disease;
kidney disease;
gallstones;
lupus;
congestive heart failure;
gout, or high levels of uric acid in your blood;
asthma or allergies;
high cholesterol or triglyceride levels;
an allergy to penicillin;
glaucoma; or
if you are on a low-salt diet.
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
You should not breastfeed while using this medicine.
Hydrochlorothiazide and valsartan is not approved for use by anyone younger than 18 years old.
How should I take hydrochlorothiazide and valsartan?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take  hydrochlorothiazide and valsartan with or without food.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.
Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated.
If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and valsartan.
It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
