Get emergency medical help if you have signs of an allergic reaction to pravastatin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, pravastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.
Call your doctor right away if you have:
muscle weakness in your hips, shoulders, neck, and back;
trouble lifting your arms, trouble climbing or standing; or
liver problems - loss of appetite, stomach pain (upper right side), tiredness, dark urine, jaundice (yellowing of the skin or eyes).
Common pravastatin side effects may include:
muscle or joint pain;
nausea, vomiting, diarrhea;
headache; or
cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Pravastatin side effects (more detail)
