Usual Adult Dose for Leukemia:
Chronic Phase CML:
100 mg orally once a day
Duration of therapy: Until disease progression or patient is intolerant.
Accelerated Phase CML, Myeloid or Lymphoid Blast Phase CML, Ph+ ALL:
140 mg orally once a day
Duration of therapy: Until disease progression or patient is intolerant
Comments:
-This drug should be used at the lowest effective dose in order to achieve therapeutic efficacy and minimize adverse effects.
-The effect of discontinuing therapy after complete cytogenetic response is achieved has not been investigated.
Uses: Chronic phase, accelerated phase, or myeloid or lymphoid blast phase Philadelphia chromosome-positive chronic myelogenous leukemia; Philadelphia chromosome-positive acute lymphoblastic leukemia
 Detailed Sprycel dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
