Certain other medicines or herbal products may make etonogestrel less effective, which could result in pregnancy. You may need to use a non-hormonal form of back-up birth control (such as condoms with spermicide) while you are taking certain medicine, and for up to 28 days after stopping the medicine.
Tell your doctor about all your current medicines and any other medicines you start or stop using, especially:
aprepitant;
bosentan;
griseofulvin;
rifampin;
St. John's wort;
topiramate;
medicine to treat hepatitis C, HIV, or AIDS;
a barbiturate - butabarbital, secobarbital, phenobarbital (Solfoton); or
seizure medicine - carbamazepine, felbamate, oxcarbazepine, phenytoin.
This list is not complete. Other drugs may interact with etonogestrel, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
 Nexplanon drug interactions (more detail)
