You should not use Invokana if you have severe kidney disease or if you are on dialysis.
Invokana can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.
Before taking this medicine
You should not use Invokana if you are allergic to canagliflozin, or if you have:
severe kidney disease (or if you are on dialysis).
Invokana may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
heart problems;
a diabetic foot ulcer or amputation;
circulation problems or nerve problems in your legs or feet;
kidney disease;
liver disease;
bladder infections or other urination problems;
a pancreas disorder;
if you drink often, or drink large amounts of alcohol;
if you are eating less than usual; or
if you are on a low salt diet.
Follow your doctor's instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.
You should not use canagliflozin during the second or third trimester of pregnancy.
You should not breast-feed while using this medicine.
Invokana is not approved for use by anyone younger than 18 years old.
How should I take Invokana?
Invokana is usually taken once per day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Invokana is usually taken once per day, before the first meal of the day.
You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Drink plenty of liquids while you are taking Invokana.
You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).
Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
Invokana is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using canagliflozin.
Store at room temperature away from moisture and heat.
