Using Duopa with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
metoclopramide;
mineral or vitamin supplements that contain iron;
blood pressure medicine; or
medicine to treat mood disorders or mental illness such as schizophrenia.
This list is not complete. Other drugs may interact with carbidopa and levodopa, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Duopa drug interactions (more detail)
