Ultomiris (ravulizumab) is a monoclonal antibody. Monoclonal antibodies are man-made antibodies that fight antigens (harmful substances) in the body.
Ultomiris injection is used to treat paroxysmal nocturnal hemoglobinuria (PNH) in adults and children who are at least 1 month old.
PNH is a rare genetic disorder in which defective red blood cells break down prematurely and leak hemoglobin into your blood. Hemoglobin is the iron-rich protein that gives blood its red color. When hemoglobin passes into your urine, it can appear dark or tea-colored (especially in the morning or after sleep, when the urine is most concentrated).
Ultomiris is also used to treat a rare chronic blood disease called hemolytic uremic syndrome (aHUS) in adults and children who are at least 1 month old. This medicine is not for use in treating HUS that is related to Shiga toxin E. coli.
Ultomiris is available only under a special program. You must be registered in the program and understand the risks and benefits of this medicine.
