Entyvio can cause serious side effects on your brain or liver, and may cause a serious infection. Call your doctor right away if you have a fever, tiredness, muscle aches, sore throat, shortness of breath, skin sores, painful urination, loss of appetite, upper stomach pain, dark urine, yellowing of your skin and eyes, or problems with speech, thought, vision, or muscle movement.
Tell your caregivers if you have any reactions during the injection, such as dizziness, nausea, itching, headache, chest tightness, trouble breathing, or swelling in your face.
Do not receive a "live" vaccine while using Entyvio.
Before taking this medicine
You should not use Entyvio if you are allergic to vedolizumab.
To make sure Entyvio is safe for you, tell your doctor if you have ever had:
an active or recent infection;
liver disease;
signs of infection such as fever, cough, or flu symptoms;
if you are scheduled to receive any vaccines.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.
You should be up to date with all needed vaccinations before receiving Entyvio.
Tell your doctor if you are pregnant or plan to become pregnant. Having active UC or Crohn's disease during pregnancy may increase the risk of premature birth or low birth weight. The benefit of treating these conditions may outweigh any risks to the baby.
If you use Entyvio while you are pregnant, make sure any doctor caring for your new baby knows that you used the medicine during pregnancy. Being exposed to vedolizumab in the womb could affect your baby's vaccination schedule during the first few months of life.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of vedolizumab on the baby.
Tell your doctor if you are breastfeeding.
How is Entyvio given?
Entyvio is given as an infusion into a vein, usually once every 2 to 8 weeks. A healthcare provider will give you this injection.
Before you start treatment with Entyvio, your doctor may perform tests to make sure you do not have tuberculosis or other infections.
This medicine must be given slowly, and the infusion can take at least 30 minutes to complete.
You will be watched closely for a short time after receiving Entyvio, to make sure you do not have an allergic reaction.
It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 14 weeks of treatment.
