(731,'qutenza','Usual Adult Dose for Postherpetic Neuralgia:\nUp to 4 patches applied to intact, non-irritated, dry skin, and allowed to remain in place for 30 minutes for the feet and 60 minutes for other locations\nComments:\n-Treatment may be repeated not more frequently than every three months.\n-The patch should be applied by a physician or by a health care professional under the supervision of a physician.\nUsual Adult Dose for Diabetic Peripheral Neuropathy (DPN) of the Feet:\nUp to 4 patches applied to intact, non-irritated, dry skin, and allowed to remain in place for 30 minutes.\nComments:\n-Treatment may be repeated not more frequently than every three months.\n-The patch should be applied by a physician or by a health care professional under the supervision of a physician.\n Detailed Qutenza dosage information\nWhat happens if I miss a dose?\nA missed dose of Qutenza will not cause harm but may make the medication less effective reducing substance P and relieving your pain.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222, especially if anyone has accidentally swallowed it.\nAccidental swallowing of capsaicin can cause severe burning in or around the mouth, watery eyes, runny nose, and trouble swallowing or breathing.\nExcessive use of Qutenza can cause severe burning or redness.\n','It is not likely that other drugs you take orally or inject will have an effect on topically applied capsaicin. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n Qutenza drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Qutenza patches: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nWash the skin and get medical attention right away if you have severe burning, pain, swelling, or blistering of the skin where you applied this medication.\nStop using Qutenza and call your doctor at once if you have:\nskin redness where the medicine was applied; or\ntrouble breathing or swallowing (after accidental inhalation of capsaicin odor or dried residue).\nLess serious side effects may include a mild burning sensation that can last for several hours or days, especially after your first use of Qutenza.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Qutenza side effects (more detail)\n','Qutenza patches contain capsaicin. Capsaicin is the active ingredient in chili peppers that makes them hot.\nQutenza patches are used to treat nerve pain (neuralgia) in people who have had herpes zoster, or \"shingles.\"\nQutenza patches are also used to treat nerve pain (neuralgia) associated with diabetic peripheral neuropathy (DPN) of the feet.\n','Qutenza patches must be applied only by a healthcare professional.\nDo not use Qutenza if you are allergic to chili peppers, or if you have ever had an allergic reaction to capsaicin topical.\nCapsaicin can cause a burning sensation wherever it is applied. If you have significant discomfort or skin redness, it can be treated with an ice pack or pain relieving medication.\nGet medical attention right away if you have severe burning, pain, swelling, or blistering of the skin where you applied the Qutenza patches.\nBefore using this medicine\nDo not use Qutenza if you are allergic to chili peppers, or if you have ever had an allergic reaction to capsaicin topical.\nAsk a doctor or pharmacist about using Qutenza if you have any allergies (especially to plants), or if you have a serious medical condition.\nIt is not known whether Qutenza will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.\nIt is not known whether capsaicin topical passes into breast milk or if it could harm a nursing baby. Do not apply Qutenza to your breast area if you are breast-feeding a baby.\nDo not use this medication on anyone younger than 18 years old without the advice of a doctor.\nHow should I use Qutenza?\nUse Qutenza exactly as directed. Qutenza patches must be applied only by a healthcare professional.\nDo not touch Qutenza, treatment areas, and all used supplies or other materials placed in contact with the treatment area without wearing nitrile gloves.\nDo not take by mouth. This medicine is for use only on the skin.\nDo not use Qutenza on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. If this medicine gets in your eyes, nose, mouth, rectum, or vagina, rinse with water.\nMake sure your skin is clean and dry before you apply the patch.\nPre-treat the area with a topical anesthetic to reduce discomfort associated with the application of Qutenza.\nApply topical anesthetic to the entire treatment area and surrounding 1 to 2 cm, and keep the local anesthetic in place until the skin is anesthetized prior to the application of a Qutenza patch.\nQutenza patches must be applied only by a healthcare professional. Tear open the pouch along the three dashed lines and remove the patch.\nInspect the patch and identify the outer surface backing layer with the printing on one side and the capsaicin-containing adhesive on the other side. The adhesive side of the patch is covered by a clear, unprinted, diagonally-cut release liner.\nCut the patch before removing the protective release liner. The diagonal cut in the release liner is to aid in its removal. Peel a small section of the release liner back, and place the adhesive side of the patch on the treatment area.\nWhile you slowly peel back the release liner from under the patch with one hand, use your other hand to smooth the patch down on to the skin.\nOnce the Qutenza patch is applied, leave in place for 60 minutes for postherpetic neuralgia, and 30 minutes for diabetic peripheral neuropathy of the feet.\nTo keep the medication from getting on your hands when you apply it, use nitrile gloves. Wear nitrile gloves at all times while handling Qutenza and cleaning treatment areas.\nCapsaicin can cause a burning sensation wherever it is applied.\nIf the burning sensation is painful or causes significant discomfort, wash the treated skin area with soap and cool water. Get medical attention right away if you have severe burning, pain, swelling, or blistering.\nDo not cover treated skin with a bandage or heating pad, which can increase the burning sensation. You may cover the skin with clothing.\nAvoid taking a bath or shower within 1 hour before or after you apply capsaicin to your skin. Also avoid direct sunlight, swimming or vigorous exercise. Warm water or perspiration can increase the burning sensation caused by capsaicin.\nAvoid getting Qutenza in your eyes or near your nose where you might inhale it. If it does get into any of these areas, rinse thoroughly with water.\nUse only nitrile gloves when handling Qutenza, and when cleaning capsaicin residue from the skin. Do not use latex gloves as they do not provide adequate protection.\nAlso avoid getting this medication on contact lenses, dentures, and other items that come into contact with sensitive areas of your body.\nFor best results, keep using the medication as directed. Pain relief should occur gradually as the substance P in your body is decreased in the nerve cells.\nCall your doctor if your pain does not improve after using this medication for 7 days, or if your symptoms get worse or get better and then come back in a few days.\nStore Qutenza at room temperature away from moisture and heat, in a place where children and pets cannot get to it.\n','Avoid inhaling the odor or dried residue of Qutenza. Inhaling capsaicin can cause coughing, sneezing, or watery eyes, and can irritate your throat or lungs.\nAvoid touching your eyes, mouth, nose, genitals, or rectum until the medication has been washed off your hands. Also avoid handling food while the medication is still on your hands.\nAvoid exposing treated skin to sunlight, sunlamps, tanning beds, or a hot tub. Capsaicin can cause a burning sensation that may be made worse by heat.\nDo not use other medicated skin products, including muscle pain creams or lotions, on areas where you have applied Qutenza, unless your doctor has told you to.\n');
INSERT INTO `drugs` VALUES (732,'qvar','This section provides information on the proper use of a number of products that contain beclomethasone.  It may not be specific to Qvar. Please read with care.\nInhaled beclomethasone is used to prevent asthma attacks. It is not used to relieve an asthma attack that has already started. For relief of an asthma attack that has already started, you should use another medicine. If you do not have another medicine to use for an attack or if you have any questions about this, check with your doctor.\nInhaled beclomethasone is used with a special inhaler that comes with patient directions. Read the directions carefully before using this medicine. If you do not understand the directions or you are not sure how to use the QVAR® inhaler or QVAR® Redihaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you use the inhaler to make sure you are using it properly.\nUse this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine without telling your doctor. To do so may increase the chance of side effects.\nIn order for this medicine to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor.\nDo not stop using this medicine or other asthma medicines that your doctor has prescribed for you unless you have discussed this with your doctor.\nTo use the QVAR® inhaler:\nDo not use the inhaler for this medicine with any other medicine. Do not remove the canister from the actuator.\nRemove the cap and look at the mouthpiece to make sure it is clean.\nBefore you use an inhaler for the first time, prime it by pointing it away from your face and spraying into the air 2 times. If the inhaler has not been used for 10 days or longer, prime it again.\nTo inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it. Do not block the mouthpiece with your teeth or tongue.\nWhile pressing down firmly and fully on the metal canister, breathe in through your mouth as deeply as you can until you have taken a full deep breath.\nTake the inhaler out of your mouth. Hold your breath for about 10 seconds, then breathe out slowly.\nIf you are supposed to use more than one puff, wait 1 to 2 minutes before inhaling the second puff. Repeat these steps for the next puff.\nWipe the mouthpiece dry with a cloth or tissue. Do not wash it with water. Put the cap back on right away.\nGargle and rinse your mouth with water after each dose.\nThe inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The doses counting down from 20 to 0 will show up in red to remind you to refill your prescription. Throw away the inhaler when the count is 0. You may not receive the right amount of medicine.\nTo use the QVAR® Redihaler™:\nTake the inhaler out of the carton before you use it for the first time.\nDo not use the inhaler for this medicine with any other medicine.\nThis medicine does not require priming. Do not shake the inhaler. Do not use it with a spacer or volume holding chamber.\nAlways use the inhaler in an upright position with the mouthpiece facing downwards.\nDo not open the white cap of the inhaler or leave it open unless you are ready to use it. Close the cap before each use or if it has been left open for more than 2 minutes.\nTo inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it.\nBreathe in through your mouth as deeply as you can until you have taken a full deep breath.\nHold your breath and remove the mouthpiece from your mouth. Continue holding your breath as long as you can up to 10 seconds before breathing out slowly. This gives the medicine time to settle in your airways and lungs.\nClose the white cap to prepare for the next inhalation.\nIf your doctor has told you to take more than 1 inhalation per dose, make sure the cap is closed and repeat the previous steps.\nKeep the inhaler dry and clean at all times. Gently wipe the mouthpiece with a dry cloth or tissue as needed. Do not wash or put any part of the inhaler in water.\nThe inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The doses counting down from 20 to 0 will show up in red to remind you to refill your prescription. Throw away the inhaler when the dose counter displays 0 after opening the carton.\nRinsing your mouth with water after each dose may help prevent hoarseness, throat irritation, and infection in the mouth. However, do not swallow the water after rinsing.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor inhalation dosage form (aerosol):\nQVAR® inhaler:\nFor preventing an asthma attack:\nFor patients who have received bronchodilators alone:\nAdults and children 12 years of age and older—At first, one puff two times a day. Each puff contains 40 or 80 micrograms (mcg) of beclomethasone. Your doctor may increase your dose as needed. However, the dose is usually not more than 320 mcg two times a day.\nChildren 5 to 11 years of age—At first, one puff two times a day. Each puff contains 40 mcg of beclomethasone. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mcg two times a day.\nChildren younger than 5 years of age—Use and dose must be determined by your doctor.\nFor patients who have received inhaled corticosteroids:\nAdults and children 12 years of age and older—At first, one to two puffs two times a day. Each puff contains 40 or 80 micrograms (mcg) of beclomethasone. Your doctor may increase your dose as needed. However, the dose is usually not more than 320 mcg two times a day.\nChildren 5 to 11 years of age—At first, one puff two times a day. Each puff contains 40 mcg of beclomethasone. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mcg two times a day.\nChildren younger than 5 years of age—Use and dose must be determined by your doctor.\nQVAR® Redihaler™:\nFor preventing an asthma attack:\nFor patients who have not received inhaled corticosteroids:\nAdults and children 12 years of age and older—At first, 40 to 80 micrograms (mcg) beclomethasone 2 times a day. The doses should be at least 12 hours apart. Your doctor may increase your dose as needed. However, the dose is usually not more than 320 mcg two times a day.\nChildren 4 to 11 years of age—At first, 40 mcg of beclomethasone 2 times a day. The doses should be at least 12 hours apart. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mcg two times a day.\nChildren younger than 4 years of age—Use and dose must be determined by your doctor.\nMissed dose\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nIf you miss a dose of QVAR® Redihaler™, skip the missed dose and go back to your regular dosing schedule.\nStorage\nStore the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\n Detailed Qvar RediHaler dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nMore common\nBody aches or pain\ncongestion\ncough\ndifficulty with breathing\ndryness or soreness of the throat\nfever\nhoarseness\nrunny nose\ntender, swollen glands in the neck\ntrouble swallowing\nvoice changes\nIncidence not known\nAttack, assault, or force\nblindness\nblurred vision\nchanges in behavior\nchills\ndarkening of the skin\ndecreased vision\ndiarrhea\ndizziness\neye pain\nfainting\nheadache\nloss of appetite\nlower back or side pain\nmental depression\nnausea\npainful or difficult urination\nskin rash\nsore mouth or tongue\ntearing\nthoughts of killing oneself\nunusual tiredness or weakness\nvomiting\nwhite patches in the mouth or on the tongue\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nLess common\nCramps\nheavy bleeding\npain\npain or tenderness around the eyes and cheekbones\nstuffy or runny nose\ntightness of the chest\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Qvar RediHaler side effects (more detail)\n','Beclomethasone is used to help control the symptoms of asthma and improve breathing. It is used when a patient\'s asthma has not been controlled sufficiently on other asthma medicines, or when a patient\'s condition is so severe that more than one medicine is needed every day. This medicine will not relieve an asthma attack that has already started.\nBeclomethasone belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines). It works by preventing certain cells in the lungs and breathing passages from releasing substances that cause asthma symptoms.\nThis medicine is available only with your doctor\'s prescription.\n','If you will be using this medicine for a long time, it is very important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.\nThis medicine may cause fungus infection of the mouth or throat (thrush). Tell your doctor right away if you or your child have white patches in the mouth or throat, or pain when eating or swallowing.\nYou should not use this medicine if your asthma attack has already started. Your doctor will prescribe another medicine (eg, a short-acting inhaler) for you to use in case of an acute asthma attack. Make sure you understand how to use the short-acting inhaler. Talk to your doctor if you need instructions.\nTalk with your doctor or get medical care right away if:\nYour or your child\'s symptoms do not improve after using this medicine for 2 weeks or if they become worse.\nYou or your child have a big decrease in your peak flow when measured as directed by your doctor.\nUsing too much of this medicine or using it for a long time may cause problems with your adrenal gland. Talk to your doctor if you or your child have more than one of these symptoms while you are using this medicine: darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.\nFollow your doctor\'s directions carefully if you are switching from an oral corticosteroid to this medicine.\nYour doctor may want you to carry a medical identification (ID) card stating that you or your child are using this medicine. The card will say that you may need additional medicine during an emergency, a severe asthma attack or other illness, or unusual stress.\nThis medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. This may be life-threatening. Check with your doctor right away if you or your child are having a cough, difficulty with breathing, shortness of breath, or wheezing after using this medicine. Use a short acting inhaler right away to treat your symptoms.\nIf you or your child develop a skin rash, hives, or any allergic reaction to this medicine, check with your doctor as soon as possible.\nThis medicine may cause children to grow more slowly than usual. Talk to your child\'s doctor if you have any concerns.\nThis medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, ask your doctor.\nCheck with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you or your child to have your eyes checked by an ophthalmologist (eye doctor).\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.\n',NULL),(733,'qvar-redihaler','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nQvar Redihaler is not a rescue medicine for asthma attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your asthma medications are not working as well.\nRead and carefully follow any instructions for using  Qvar Redihaler, priming the inhaler device, and cleaning the device. Ask your doctor or pharmacist if you do not understand these instructions.\nDo not allow a young child to use this medicine without help from an adult.\nIf you also use an oral steroid medication, you should not stop using it suddenly. Follow your doctor\'s instructions about tapering your dose.\nTo reduce the chance of developing a yeast infection in your mouth, rinse with water (but do not swallow) after using Qvar Redihaler.\nIt may take up to 4 weeks or longer before your symptoms improve. Keep using the medicine and call your doctor if your symptoms do not begin to improve after 2 weeks.\nYou should not stop using Qvar Redihaler suddenly. Stopping suddenly may make your condition worse.\nUse all asthma medications as directed. Your dose needs may change due to surgery, illness, stress, or a recent asthma attack. Do not change your dose or stop using a medicine without your doctor\'s advice. Tell your doctor if any of your medicines seem to stop working.\nStore at room temperature away from moisture and heat. Keep the cover on your inhaler when not in use. Keep away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.\nThrow away the inhaler device when the inhalations counter shows \"0\" or the expiration date on the label has passed. Get your prescription refilled before you run out of medicine completely.\n Detailed Qvar RediHaler dosage information\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may affect Qvar Redihaler, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Qvar RediHaler drug interactions (more detail)\nDoes Qvar RediHaler interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nBeclomethasone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medicine.\nCall your doctor at once if you have:\nwheezing, choking, or other breathing problems after using this medicine;\nworsening asthma symptoms;\nwhite patches or sores inside your mouth or on your lips;\nblurred vision, tunnel vision, eye pain, or seeing halos around lights;\nsigns of infection--fever, chills, body aches, vomiting;\nsigns of low adrenal gland hormones--worsening tiredness, lack of energy, weakness, feeling light-headed, nausea, vomiting; or\nincreased adrenal gland hormones--hunger, weight gain, swelling, skin discoloration, slow wound healing, sweating, acne, increased body hair, tiredness, mood changes, muscle weakness, missed menstrual periods, sexual changes.\nCommon side effects may include:\na yeast infection in the mouth;\nsinus pain, irritation in your nose; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Qvar RediHaler side effects (more detail)\n','Beclomethasone is an inhaled steroid that is used to prevent asthma attacks in adults and children at least 4 years old.\nQvar Redihaler will not treat an asthma attack that has already begun.\nQvar Redihaler may also be used for purposes not listed in this medication guide.\n','Seek medical attention if your breathing problems get worse quickly, or if you think your asthma medications are not working as well.\nBefore taking this medicine\nYou should not use beclomethasone if you are allergic to it.\nTell your doctor if you have ever had:\nany type of bacterial, fungal, or viral infection;\ntuberculosis;\nherpes infection of the eyes;\nosteoporosis, or low bone mineral density;\na weak immune system; or\ncataracts, glaucoma, or increased pressure inside your eyes.\nTell your doctor if you are pregnant or breastfeeding.\n','Rinse with water if  Qvar Redihaler gets in your eyes.\nAvoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using steroid medication.\n'),(734,'qwo',NULL,NULL,'Qwo may cause serious side effects, including:\nAllergic (hypersensitivity) reactions, including anaphylaxis. Call your healthcare provider right away if you have any of these symptoms of an allergic reaction after an injection of Qwo:\nhives\ntrouble breathing\nlow blood pressure\nswollen face\nchest pain\ndizziness or fainting\nInjection site bruising.\nThe most common side effects include bruising, pain, areas of hardness, itching, redness, discoloration, swelling and warmth in the treatment area.\nThese are not all of the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA 1088.\n Qwo side effects (more detail)\nGeneral information about Qwo\nMedicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. If you would like more information, talk to your healthcare provider. You can ask your pharmacist or healthcare provider for information that is written for health professionals.\nWhat are the ingredients in Qwo?\nActive ingredient: collagenase clostridium histolyticum\nInactive ingredients: mannitol, sucrose, tromethamine, and hydrochloric acid\nThe diluent contains: calcium chloride dihydrate, sodium chloride, and Water for Injection, USP\n','Qwo is a prescription medicine used for the treatment of moderate to severe cellulite in the buttocks of adult women.\nIt is not known if this medicine is safe and effective in children.\nWho should not receive Qwo?\nYou should not receive Qwo if you:\nAre allergic to any collagenase or to any of the ingredients. See the end of this page for a complete list of ingredients.\nHave an active infection in the treatment area.\nBefore receiving Qwo\nBefore receiving Qwo, tell your healthcare provider about all of your medical conditions, including if you:\nhave had an allergic reaction to a Qwo injection in the past\nhave a bleeding problem\nare pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby.\nare breastfeeding or plan to breastfeed. It is not known if this medicine passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you receive Qwo.\nTell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that prevents the clotting of your blood (antiplatelet or anticoagulant medicine).\nHow will I receive Qwo?\nQwo is injected into the fat (subcutaneously) of each single buttock (treatment area) by your healthcare provider. You may receive up to 12 injections per treatment area.\nEach treatment visit may include up to 2 treatment areas.\nQwo injections will be given 21 days apart for 3 treatment visits.\n',NULL,NULL),(735,'rabeprazole','Rabeprazole is usually taken once per day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nRabeprazole is for short-term use only, usually 4 to 8 weeks. Your doctor may recommend a second course of treatment if you need additional healing time.\nAcipHex Sprinkle should not be given to a child younger than 1 year old.\nTake  rabeprazole with a full glass of water.\nIf you take rabeprazole to treat duodenal ulcers, take the medicine after a meal. If you take rabeprazole to prevent ulcers caused by Helicobacter pylori, take the medicine with food. If you take rabeprazole for any other condition, you may take the medicine with or without food.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nSwallow the tablet whole and do not crush, chew, or break it.\nDo not swallow a delayed-release capsule (AcipHex Sprinkle) whole. Open it and sprinkle the medicine into a spoonful of soft food such as applesauce, yogurt, or baby food made from fruit or vegetable. You may also mix the medicine with apple juice, Pedialyte, or infant formula. Swallow the mixture right away without chewing. Do not save it for later use.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using rabeprazole.\nSome conditions are treated with a combination of rabeprazole and antibiotics. Use all medications as directed.\nTake your medicines for the full prescribed length of time, even if your symptoms quickly improve.\nCall your doctor if your symptoms do not improve, or if they get worse while using rabeprazole.\nStore at room temperature away from moisture and heat.\n Detailed Rabeprazole dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your current medicines. Many drugs can affect rabeprazole, especially:\nan antibiotic such as clarithromycin or amoxicillin;\ndigoxin;\na diuretic or \"water pill\";\nmethotrexate; or\nwarfarin (Coumadin, Jantoven).\nThis list is not complete and many other drugs may affect rabeprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rabeprazole drug interactions (more detail)\nDoes Rabeprazole interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody;\nsudden pain or trouble moving your hip, wrist, or back;\nseizure (convulsions);\nkidney problems--fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, swelling, rapid weight gain;\nnew or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight;\nlow magnesium--dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or\nsigns of bleeding (if you also take warfarin)--headaches, dizziness, weakness; pain or swelling; bruising, unusual bleeding (nosebleeds, bleeding gums); red or pink urine; heavy menstrual flow; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or any bleeding that will not stop.\nTaking rabeprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.\nIf you use rabeprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.\nCommon side effects may include:\ninfection;\npain;\nsore throat;\nheadache;\nnausea, vomiting;\ngas, diarrhea, constipation; or\nstomach pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rabeprazole side effects (more detail)\n','Rabeprazole is used short-term to treat symptoms of gastroesophageal reflux disease (GERD) in adults and children who are at least 1 year old.\nRabeprazole is used only in adults to treat conditions involving excessive stomach acid, such as Zollinger-Ellison syndrome. Rabeprazole is also used in adults to promote healing of duodenal ulcers or erosive esophagitis (damage to your esophagus caused by stomach acid).\nRabeprazole may also be given with an antibiotic to prevent duodenal ulcer caused by infection with Helicobacter pylori (H. pylori).\nRabeprazole is not for immediate relief of heartburn symptoms.\nRabeprazole may also be used for purposes not listed in this medication guide.\n','Rabeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.\nDiarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.\nRabeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.\nYou may be more likely to have a broken bone while taking  rabeprazole long term or more than once per day.\nBefore taking this medicine\nHeartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.\nYou should not use this medicine if you are allergic to rabeprazole or:\nif you also take any medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey);\nif you had breathing problems, kidney problems, or a severe allergic reaction after taking rabeprazole in the past; or\nif you are also allergic to medicines like rabeprazole, such as esomeprazole, lansoprazole, omeprazole, pantoprazole , Nexium, Prevacid, Prilosec, Protonix, and others.\nTell your doctor if you have ever had:\nliver disease;\nosteoporosis or low bone mineral density (osteopenia);\nlupus (an autoimmune disorder); or\nlow levels of magnesium in your blood.\nYou may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.\nTell your doctor if you are pregnant or breastfeeding.\nDo not give this medicine to a child without medical advice. Certain forms and strengths of rabeprazole should not be given to a child younger than 12 years old.\n',' rabeprazole can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.\n'),(736,'raloxifene','Usual Adult Dose for Osteoporosis:\n60 mg orally per dayComments:-For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate.  -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known.Uses:-Treatment and prevention of osteoporosis in postmenopausal women.-Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.\nUsual Adult Dose for Prevention of Osteoporosis:\n60 mg orally per dayComments:-For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate.  -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known.Uses:-Treatment and prevention of osteoporosis in postmenopausal women.-Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.\nUsual Adult Dose for Prevention of Breast Cancer:\n60 mg orally per dayComments:-For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate.  -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known.Uses:-Treatment and prevention of osteoporosis in postmenopausal women.-Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.\n Detailed Raloxifene dosage information\n','Tell your doctor about all your other medicines, especially:\ncholestyramine;\nwarfarin (Coumadin, Jantoven); or\nbirth control pills or hormone replacement therapy.\nThis list is not complete. Other drugs may affect raloxifene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Raloxifene drug interactions (more detail)\nDoes Raloxifene interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using raloxifene and call your doctor at once if you have:\nswelling, tenderness, or other changes in your breasts;\nsigns of a stroke--sudden numbness or weakness (especially on one side of the body), slurred speech, vision problems;\nsigns of a blood clot in the lung--chest pain, trouble breathing, coughing up blood; or\nsigns of a blood clot deep in the body--swelling, warmth, or redness in an arm or leg.\nCommon side effects may include:\nhot flashes;\nleg cramps;\nswelling in your hands, feet, or ankles;\njoint pain;\nflu symptoms; or\nincreased sweating.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Raloxifene side effects (more detail)\n','Raloxifene is used to treat osteoporosis in postmenopausal women.\nRaloxifene is not for use in men.\nRaloxifene may also be used for purposes not listed in this medication guide.\n',' raloxifene may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take raloxifene if you have ever had this type of blood clot.\nRaloxifene can also increase your risk of a stroke, which can be fatal. This risk is highest if you have certain risk factors (such as smoking, having heart problems or high blood pressure, or if you have ever had a heart attack or a stroke).\nAlthough this medicine is for use only in postmenopausal women, you should not take raloxifene if you are pregnant or breastfeeding.\nBefore taking this medicine\nThis medicine may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take raloxifene if you have ever had this type of blood clot.\nThis medicine is for use only in women who can no longer get pregnant. Raloxifene can harm an unborn baby. Do not use if you are pregnant or may become pregnant.\nDo not breastfeed while taking raloxifene.\nRaloxifene can increase your risk of a stroke, which can be fatal. Tell your doctor if you have ever had:\nheart problems, irregular heartbeats;\na heart attack or stroke, including \"mini-stroke\";\nhigh blood pressure;\ncancer; or\nif you smoke.\nTell your doctor if you have ever had:\na blood clot;\nhigh triglycerides caused by using estrogen;\nliver or kidney disease;\nendometriosis;\nabnormal vaginal bleeding; or\nif you have not gone through menopause.\nHow should I take raloxifene?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake the medicine at the same time each day, with or without food.\nIf you need major surgery or will be on long-term bed rest, you will need to stop taking raloxifene at least 3 days ahead of time. You may not be able to restart the medicine until you are active again. Tell any doctor or surgeon who treats you that you take raloxifene.\nRaloxifene is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin D supplements. Follow your doctor\'s instructions very closely.\nYour doctor should check your progress on a regular basis. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','If you take calcium supplements, do not take more than your doctor has prescribed. Taking more calcium than recommended will not provide extra protection for your bones, and may cause serious side effects including kidney stones.\nAvoid sitting still for long periods of time during travel while you are taking raloxifene.\n'),(737,'ramelteon','Usual Adult Dose for Insomnia:\n8 mg orally within 30 minutes of going to bedMaximum Dose: 8 mg per dayComments: This drug should not be taken with or immediately after a high-fat meal.Use: Treatment of insomnia characterized by difficulty with sleep onset\n Detailed Ramelteon dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Using ramelteon with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nSometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may affect ramelteon, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ramelteon drug interactions (more detail)\n','Ramelteon may cause a severe allergic reaction. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; nausea and vomiting; swelling of your face, lips, tongue, or throat.\nSome people using this medicine have engaged in activity while not fully awake and later had no memory of it. This may include walking, driving, eating, having sex, or making phone calls. If this happens to you, call your doctor right away.\nCall your doctor at once if you have:\nunusual thoughts or behavior, hallucinations, worsening depression, thoughts about hurting yourself;\na missed menstrual period;\nnipple discharge; or\nloss of interest in sex.\nCommon side effects may include:\ndrowsiness, tired feeling;\ndizziness;\nnausea; or\nworsening sleep problems.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ramelteon side effects (more detail)\n','Ramelteon is a sedative, also called a hypnotic. It works by affecting certain substances in your body that help regulate your \"sleep-wake cycle.\"\nRamelteon is used to treat insomnia that is associated with having trouble falling asleep.\nRamelteon may also be used for purposes not listed in this medication guide.\n','You should not use ramelteon if you are also taking fluvoxamine, or if you have ever had a severe allergic reaction to ramelteon.\nRamelteon may cause a severe allergic reaction. Get emergency medical help if you have hives; difficult breathing; nausea and vomiting; swelling of your face, lips, tongue, or throat.\nSome people using  ramelteon have engaged in activity while not fully awake and later had no memory of it. If this happens to you, call your doctor right away.\nBefore taking this medicine\nRamelteon will make you fall asleep. Never take this medicine during your normal waking hours, unless you have at least 7 to 8 hours to dedicate to sleeping.\nYou should not use ramelteon if you are allergic to it, or if:\nyou have severe liver disease; or\nyou also take fluvoxamine.\nTell your doctor if you have ever had:\nliver disease;\nbreathing problems;\nsleep apnea (breathing stops while you are asleep); or\ndepression, mental illness, or suicidal thoughts.\nTell your doctor if you are pregnant or breastfeeding.\nYou should not breastfeed within 25 hours after using ramelteon. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.\nRamelteon may affect the levels of male or female hormones (testosterone or prolactin). This may affect menstrual periods in women, sexual desire in men, or fertility (ability to have children) in either a man or a woman.\nRamelteon is not approved for use by anyone younger than 18 years old.\nHow should I take ramelteon?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nTake ramelteon 30 minutes before your normal bedtime.\nSwallow the tablet whole and do not crush, chew, or break it.\nRamelteon should not be taken with or after a high-fat meal. This will make it harder for your body to absorb the medication.\nCall your doctor if your symptoms do not improve after 7 to 10 days of using ramelteon.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\nWhat happens if I miss a dose?\nSince ramelteon is taken only at bedtime if needed, you are not likely to miss a dose. Never take this medication if you do not have 7 to 8 hours to sleep before being active again.\nDo not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Do not drink alcohol with  ramelteon.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(738,'ramipril','Take ramipril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nRamipril can be taken with or without food.\nSwallow the tablet whole.\nYou may open the capsule and sprinkle the medicine into a half-cup (4 ounces) of water, apple juice, or applesauce to make swallowing easier. Swallow without chewing. You may store the mixture for up to 24 hours at room temperature, or up to 48 hours in a refrigerator.\nCall your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking ramipril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.\nYour blood pressure will need to be checked often, and you may need frequent blood tests to check your potassium levels.\nDrink plenty of water each day while you are taking this medication.\nIf you need surgery, tell the surgeon ahead of time that you are using this medicine.\nIf you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Ramipril dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n',NULL,'Get emergency medical help if you have any signs of an allergic reaction to ramipril: hives; severe stomach pain; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\njaundice (yellowing of your skin or eyes);\nlittle or no urination;\nfever, chills, sore throat, cold or flu symptoms; or\nhigh potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.\nCommon ramipril side effects may include:\nheadache;\ncough; or\ndizziness, weakness, tired feeling.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ramipril side effects (more detail)\n','Ramipril (Altace) is an ACE inhibitor. ACE stands for angiotensin converting enzyme.\nRamipril is used to treat high blood pressure (hypertension) or congestive heart failure, and to improve survival after a heart attack.\nRamipril may also be used for purposes not listed in this medication guide.\n','Do not use ramipril if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.\nYou should not use ramipril if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).\nIf you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).\n','Do not use salt substitutes or potassium supplements while taking ramipril, unless your doctor has told you to.\nAvoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of ramipril.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.\n'),(739,'ranexa','Usual Adult Dose of Ranexa for Angina (Chest Pain):\nThe typical starting dose is: 500 mg orally twice daily. If needed, your doctor may increase to 1000 mg orally twice daily.\n Detailed Ranexa dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose can cause nausea, vomiting, numbness or tingling, dizziness, double vision, confusion, or fainting.\n','The following drugs can interact with ranolazine and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:\nclarithromycin;\nnefazodone;\nSt. John\'s wort;\nantifungal medicine - itraconazole, ketoconazole;\nHIV or AIDS medicine - indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir;\ntuberculosis medicine - rifabutin, rifampin, rifapentine; or\nseizure medicine-carbamazepine, phenobarbital, phenytoin.\nMany other drugs can interact with Ranexa. Below is just a partial list. Tell your doctor if you are using:\naprepitant (Emend);\narsenic trioxide (Trisenox);\nchloroquine (Aralen);\ndigoxin (Lanoxin);\nfluconazole (Diflucan);\nlovastatin (Mevacor, Altoprev, Advicor), simvastatin (Zocor, Simcor, Vytorin);\ntamsulosin (Flomax);\ntolterodine (Detrol);\nADHD medication such as atomoxetine (Strattera), dextroamphetamine (Adderall), methamphetamine (Desoxyn), methylphenidate (Ritalin, Daytrana, Metadate, Concerta);\nan antibiotic such as azithromycin (Zithromax), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), pentamidine (NebuPent, Pentam);\nan antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), duloxetine (Cymbalta), fluoxetine (Prozac, Sarafem, Symbyax), imipramine (Tofranil), mirtazepine (Remeron), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), venlafaxine (Effexor), and others;\ncancer medicine such as doxorubicin (Adriamycin, Doxil), lomustine (CeeNU), tamoxifen (Soltamox);\ncough medicine such as dextromethorphan (Delsym, Robitussin Maximum Strength, Vicks 44, and others) or dihydrocodeine (Alahist DHC, J-Max DHC, Pancof-PD, Panlor, Trezix, Welltuss EXP, and others);\nheart or blood pressure medicine such as amiodarone (Cordarone, Pacerone), betaxolol (Kerlone), captopril (Capoten), carvedilol (Coreg), diltiazem (Cartia, Cardizem), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), flecainide (Tambocor), ibutilide (Corvert), labetalol (Normodyne), metoprolol (Dutoprol, Lopressor, Toprol), mexilitene (Mexitil), nicardipine (Cardene), quinidine (Quin-G), pindolol (Visken), procainamide (Procan, Pronestyl), propafenone (Rythmol), propranolol (Inderal, InnoPran), sotalol (Betapace, Sorine), timolol (Blocadren), or verapamil (Calan, Covera, Isoptin);\nmedicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran);\nmedicine to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), fluphenazine (Permitil), haloperidol (Haldol), pimozide (Orap), promethazine (Phenergan), perphenazine (Trilafon), risperidone (Risperdal), thioridazine (Mellaril), or ziprasidone (Geodon);\nmedicine used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);\nmigraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig);\nnarcotic medication such as methadone (Methadose, Diskets, Dolophine); or\npain medication such as codeine (Tylenol #3), hydrocodone (Lortab, Vicodin, Vicoprofen), oxycodone (OxyContin, Percocet), or tramadol (Ultram, Ultracet).\nThis list is not complete and here are many other drugs that can interact with Ranexa. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.\n Ranexa drug interactions (more detail)\n','Get emergency medical help if you have any signs of an allergic reaction to Ranexa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nheadache with chest pain and severe dizziness, fast or pounding heartbeats; or\nkidney problems - little or no urination; painful or difficult urination, swelling in your feet or ankles; feeling tired or short of breath.\nCommon Ranexa side effects may include:\nnausea, constipation;\nheadache; or\ndizziness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ranexa side effects (more detail)\n','Ranexa (ranolazine) is used to treat chronic angina (chest pain). It works by improving blood flow to help the heart work more efficiently.\nRanexa is not for use during an acute (emergency) attack of angina.\nRanexa may also be used for purposes not listed in this medication guide.\n','You should not take Ranexa if you have cirrhosis of the liver.\nSerious drug interactions can occur when certain medicines are used together with ranolazine. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.\nRanexa is not for use during an acute (emergency) attack of chest pain. Continue using any other medicines prescribed by your doctor (such as nitroglycerin) to treat acute chest pain.\nBefore you take Ranexa, tell your doctor about all of your medical conditions, especially if you have a personal or family history of Long QT syndrome.\nChronic angina is often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor.\nBefore taking this medicine\nYou should not take Ranexa if you are allergic to ranolazine, or if you have cirrhosis of the liver.\nMany other drugs can interact with ranolazine and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:\nclarithromycin;\nnefazodone;\nSt. John\'s wort;\nantifungal medicine - itraconazole, ketoconazole;\nHIV or AIDS medicine - indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir;\ntuberculosis medicine - rifabutin, rifampin, rifapentine; or\nseizure medicine-carbamazepine, phenobarbital, phenytoin.\nTo make sure Ranexa is safe for you, tell your doctor if you have:\na heart rhythm disorder;\nliver disease;\nkidney disease; or\na personal or family history of long QT syndrome.\nIt is not known whether Ranexa will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.\nIt is not known whether ranolazine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nHow should I take Ranexa?\nTake Ranexa exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nRanexa may be taken with or without food.\nDo not crush, chew, or break an extended-release tablet. Swallow it whole.\nCall your doctor if your symptoms do not improve, or if they get worse while using Ranexa.\nChronic angina is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor\'s advice.\nStore Ranexa at room temperature away from moisture and heat.\n','Ranexa may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\nGrapefruit and grapefruit juice may interact with Ranexa and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.\n'),(740,'ranitidine','Because ranitidine has been withdrawn from the market in the U.S., some of the contents of this leaflet are intended for historical purposes only.\nTake ranitidine exactly as directed on the label, or as prescribed by your doctor.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nIt may take up to 8 weeks before your ulcer heals. Keep using your medications as directed and call your doctor if your symptoms do not improve after 6 weeks.\nYour doctor may recommend an antacid to help relieve pain. Carefully follow your doctor\'s directions about the type of antacid to use, and when to use it.\nStore at room temperature away from moisture, heat, and light.\n Detailed Ranitidine dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include lack of coordination, feeling light-headed, or fainting.\n','Many drugs can interact with ranitidine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ranitidine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to ranitidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using this medicine and call your doctor at once if you have:\nstomach pain, loss of appetite;\ndark urine, jaundice (yellowing of the skin or eyes);\nfever, chills, cough with mucus, chest pain, feeling short of breath;\nfast or slow heart rate;\neasy bruising or bleeding; or\nproblems with your skin or hair.\nCommon ranitidine side effects may include:\nnausea, vomiting, stomach pain; or\ndiarrhea, constipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ranitidine side effects (more detail)\n','Ranitidine was withdrawn from the market in the United States in April 2020.\nRanitidine belongs to a group of drugs called histamine-2 blockers. It works by reducing the amount of acid your stomach produces.\nRanitidine has been used to treat and prevent ulcers in the stomach and intestines. It also was used to treat conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome..\nRanitidine was also used to treat gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.\nA cancer-causing impurity found in many ranitidine medications may increase to unacceptable levels over time and when ranitidine is stored at high temperatures. As a result, the FDA has asked all makers of ranitidine to withdraw this medicine from the market in the United States.\n','Ranitidine has been withdrawn from the market in the United States. Some of the contents of this leaflet are preserved for historical purposes only.\nUsing ranitidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.\nDo not use this medication if you are allergic to ranitidine.\nAsk a doctor or pharmacist if it is safe for you to take this medicine if you have kidney disease, liver disease, or porphyria.\nHeartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.\nRanitidine granules and effervescent tablets must be dissolved in water before you take them. Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor\'s directions about the type of antacid to use, and when to use it. Avoid drinking alcohol. It can increase the risk of damage to your stomach. It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.\nBefore taking this medicine\nIf you have been taking prescription-strength ranitidine: Before you stop taking the medicine, ask your doctor about safer treatment options.\nIf you have been taking over-the-counter (OTC) ranitidine: Stop taking the medicine, and ask your doctor or pharmacist about other approved OTC stomach acid reducers.\nHeartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.\nBefore using any OTC medicine to reduce stomach acid, ask a doctor or pharmacist if the medicine is safe for you if you have other medical conditions or allergies.\nAsk a doctor before using any OTC stomach acid medicine if you are pregnant or breastfeeding.\n','You should not stop taking prescription-strength ranitidine until you ask your doctor to prescribe a different medication. Talk with doctor as soon as possible about how best to treat your condition.\nAvoid drinking alcohol. It can increase the risk of damage to your stomach.\n'),(741,'ranolazine','Usual Adult Dose for Angina Pectoris:\n500 mg orally twice a day; increase to 1000 mg orally twice a day as neededMaximum dose: 1000 mg orally twice a dayUse: Treatment of chronic angina\n Detailed Ranolazine dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Tell your doctor about all your current medicines. Many drugs can affect ranolazine, especially:\nany other medicine to treat heart disease;\nan antibiotic or antifungal medicine;\ncholesterol-lowering medicine;\noral diabetes medicine;\nmedicine to prevent organ transplant rejection;\nmedicine to treat a mental illness; or\nmedicine to treat or prevent nausea and vomiting caused by chemotherapy or radiation.\nThis list is not complete and many other drugs may affect ranolazine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Ranolazine drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\na light-headed feeling, like you might pass out;\nfast or pounding heartbeats, fluttering in your chest; or\nkidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath.\nCommon side effects may include:\nnausea, constipation;\nheadache; or\ndizziness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ranolazine side effects (more detail)\n','Ranolazine is used to treat chronic angina (chest pain). Ranolazine is not for use during an acute (emergency) attack of angina.\nRanolazine may also be used for purposes not listed in this medication guide.\n','You should not take ranolazine if you have cirrhosis of the liver.\nTell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.\nBefore taking this medicine\nYou should not take ranolazine if you are allergic to it, or if you have:\ncirrhosis of the liver.\nMany drugs can interact and cause dangerous effects. Some drugs should not be used together with ranolazine. Your doctor may change your treatment plan if you also use:\nclarithromycin;\nnefazodone;\nSt. John\'s wort;\nantifungal medicine--itraconazole, ketoconazole;\nHIV or AIDS medicine--indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir;\nseizure medicine--carbamazepine, phenobarbital, phenytoin; or\ntuberculosis medicine--rifabutin, rifampin, rifapentine.\nTell your doctor if you have ever had:\nlong QT syndrome (in you or a family member);\nliver disease; or\nkidney disease.\nTell your doctor if you are pregnant or breastfeeding.\nHow should I take ranolazine?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYou may take ranolazine with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nChronic angina is often treated with a combination of drugs. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor\'s advice.\nCall your doctor if your symptoms do not improve, or if they get worse.\nYou will need frequent medical tests to check your heart and kidney function.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nSkip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose can cause nausea, vomiting, numbness or tingling, dizziness, double vision, confusion, or fainting.\n','Avoid driving or hazardous activity until you know how  ranolazine will affect you. Your reactions could be impaired.\nGrapefruit may interact with ranolazine and lead to unwanted side effects. Avoid the use of grapefruit products.\n'),(742,'rapamune','Usual Adult Dose of Rapamune for Organ Transplant -- Rejection Prophylaxis:\nFOR PATIENTS AT LOW TO MODERATE IMMUNOLOGIC RISK:\nDosing by body weight:\n-Less than 40 kg:\nLoading dose: 3 mg/m2 on day 1\nMaintenance: 1 mg/m2 once daily\n-Greater than or equal to 40 kg:\nLoading dose: 6 mg orally on day 1\nMaintenance: 2 mg orally once daily\nIN PATIENTS AT HIGH IMMUNOLOGIC RISK (defined as Black transplant recipients and/or repeat renal transplant recipients who lost a previous allograft for immunologic reason and/or patients with high-panel reactive antibodies [PRA; peak PRA level greater than 80%]):\n-For patients receiving sirolimus with cyclosporine:\nLoading Dose: Up to 15 mg on day one post-transplantation\nMaintenance Dose: Beginning on day 2, an initial maintenance dose of 5 mg/day should be given. A trough level should be obtained between days 5 and 7, and the daily dose of sirolimus should be adjusted thereafter.\n-Antibody induction therapy may be used.\nComments:\n-It is recommended that this sirolimus be used in a regimen with cyclosporine and corticosteroids.\n-Sirolimus should be taken consistently with or without food.\n-Once the sirolimus maintenance dose is adjusted, patients should continue on the new maintenance dose for at least 7 to 14 days before further dosage adjustment with concentration monitoring.\nMAINTENANCE THERAPY AFTER WITHDRAWAL OF CYCLOSPORINE:\n-Cyclosporine withdrawal is not recommended in high-immunological risk patients. Following 2 to 4 months of combined therapy, withdrawal of cyclosporine may be considered in low-to-moderate risk patients. Cyclosporine should be discontinued over 4 to 8 weeks, and a necessary increase in the dosage of sirolimus (up to 4-fold) should be anticipated due to removal of metabolic inhibition by cyclosporine and to maintain adequate immunosuppressive effects. -Dose-adjusted trough target concentrations are typically 16 to 24 ng/mL for the first year post-transplant and 12 to 20 ng/mL thereafter (measured by chromatographic methodology).\nUsual Adult Dose of Rapamune for Pulmonary Lymphangioleiomyomatosis:\n-Initial dose: 2 mg/day\n-Sirolimus whole blood trough concentrations should be measured in 10 to 20 days, with dosage adjustment to maintain concentrations between 5 and 15 ng/mL.\nComment:\n-This drug should be taken consistently with or without food.\nUsual Pediatric Dose of Rapamune for Organ Transplant -- Rejection Prophylaxis:\nFOR PATIENTS AT LOW TO MODERATE IMMUNOLOGIC RISK:\nGreater than or equal to 13 years of age:\nDosing by body weight:\n-Less than 40 kg:\nLoading dose: 3 mg/m2 on day 1\nMaintenance: 1 mg/m2 once daily\n-Greater than or equal to 40 kg:\nLoading dose: 6 mg orally on day 1\nMaintenance: 2 mg orally once daily\n Detailed Rapamune dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your current medicines. Many drugs can interact with Rapamune, especially:\nbromocriptine (Cycloset, Parlodel);\ncyclosporine;\ndanazol;\nSt. John\'s wort;\ntacrolimus;\ncholesterol-lowering medication;\nan antibiotic or antifungal medicine;\nantiviral medicine to treat HIV or hepatitis C;\nheart or blood pressure medication;\nmedicine to reduce stomach acid or treat an ulcer; or\nseizure medicine.\nThis list is not complete and many Other drugs may interact with sirolimus. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rapamune drug interactions (more detail)\n','Rapamune may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have any change in your mental state, decreased vision, weakness on one side of your body, or problems with speech or walking. These symptoms may start gradually and get worse quickly.\nGet emergency medical help if you have signs of an allergic reaction to Rapamune: hives, rash, or peeling skin; wheezing, difficulty breathing, chest pain or tightness; feeling like you might pass out; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nredness, oozing, or slow healing of a skin wound;\na new skin lesion, or a mole that has changed in size or color;\nunusual bleeding or bruising;\nsudden chest pain or discomfort, cough, feeling short of breath;\ntenderness around the transplanted kidney;\nsigns of infection - fever, chills, painful mouth sores, skin sores, cold or flu symptoms, pain or burning when you urinate; or\nlow red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.\nCommon Rapamune side effects may include:\nfever, cold symptoms such as stuffy nose, sneezing, sore throat;\nmouth sores;\nnausea, stomach pain, diarrhea;\nheadache, muscle aches;\nchest pain;\ndizziness; or\nacne.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rapamune side effects (more detail)\n','Rapamune (sirolimus) weakens your body\'s immune system, to help keep it from \"rejecting\" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.\nRapamune is a prescription medicine used to prevent rejection (anti-rejection medicine) in people 13 years of age and older who have received a kidney transplant. Rejection is when your body\'s immune system recognizes the new organ as a \"foreign\" threat and attacks it. Rapamune is used with other medicines called cyclosporine (Gengraf, Neoral, Sandimmune), and corticosteroids.\nRapamune is also given without other medicines to treat a rare lung disorder called lymphangioleiomyomatosis (LAM). LAM affects predominantly women of childbearing age. This disorder happens mostly in women and causes lung tumors that are not cancerous but can affect breathing.\n','You should not use Rapamune if you have ever had a lung transplant or liver transplant.\nRapamune may cause your body to overproduce white blood cells. This can lead to cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure.\nCall your doctor right away if you have: fever, flu symptoms, burning when you urinate, a new skin lesion, any change in your mental state, decreased vision, weakness on one side of your body, problems with speech or walking, or pain around your transplant.\nBefore taking this medicine\nYou should not use Rapamune if you are allergic to sirolimus, or if you have ever had a lung transplant or liver transplant.\nTalk with your doctor about the risks and benefits of using this medicine. Rapamune can affect your immune system, and may cause overproduction of certain white blood cells. This can lead to cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure.\nTo make sure Rapamune is safe for you, tell your doctor if you have ever had:\nhigh cholesterol or triglycerides;\ncytomegalovirus (CMV);\nliver disease; or\na family history of skin cancer (melanoma).\nDo not use Rapamune if you are pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine, and for at least 12 weeks after your last dose.\nYou should not breast-feed while using this medicine.\nRapamune should not be given to a child younger than 13 years old.\nHow should I take Rapamune?\nTake Rapamune exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nRapamune is usually taken once a day. If you also take cyclosporine, take it at least 4 hours before you take this medicine.\nYou may take Rapamune with or without food, but take it the same way every time.\nDo not crush, chew, or break a Rapamune tablet. Tell your doctor if you have trouble swallowing the tablet whole.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nRapamune oral liquid must be mixed only with water or orange juice, no other juices or liquids. Measure the liquid carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nSirolimus can increase your risk of infection by changing the way your immune system works. You will need frequent medical tests. Your dosing schedule may be delayed based on the results of these tests.\nYou should not stop using Rapamune without your doctor\'s advice. Stopping suddenly could make your condition worse.\nStore the tablets at room temperature, away from heat, moisture, and light.\nStore the oral liquid in the refrigerator. Do not freeze. You may notice a slight haze to the liquid. This haze should disappear when the liquid reaches room temperature.\nIf you are using Rapamune oral liquid with a disposable syringe, you may store a loaded syringe in the carrying case provided. Keep the case at room temperature and use the medicine within 24 hours. Use a disposable syringe only once and then throw it away.\n','Avoid exposure to sunlight or tanning beds. Rapamune may increase your risk of skin cancer. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.\nAvoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.\nAvoid getting Rapamune oral liquid on your skin. Wash the skin with soap and water if this happens. If the medicine gets into your eyes, rinse them with plain water.\nGrapefruit may interact with sirolimus and lead to unwanted side effects. Avoid the use of grapefruit and grapefruit juice while taking Rapamune.\nDo not receive a \"live\" vaccine while using Rapamune. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).\n'),(743,'reclast','Usual Adult Dose for Paget\'s Disease:\n5 mg IV infusion, at a constant infusion rate, over no less than 15 minutes\nCalcium and vitamin D supplementation:\n-Calcium: 750 mg elemental calcium orally twice a day, or 500 mg orally three times a day\n-Vitamin D: 800 international units orally daily, especially in the 2 weeks following drug administration\nComments: Retreatment may be considered in patients who have relapsed, based on increases in serum alkaline phosphatase or failure to achieve normalization of serum alkaline phosphatase.\nUses: Paget\'s disease of bone with elevations in serum alkaline phosphatase of two times or higher than upper limit of age- specific normal reference range\nUsual Adult Dose for Osteoporosis:\n5 mg IV infusion over no less than 15 minutes, once a year\nComments: An average of at least 1200 mg calcium and 800 to 1000 international units vitamin D daily is recommended.\nUses:\n-Osteoporosis in postmenopausal women, diagnosed by bone mineral density or prevalent vertebral fracture (this drug reduces the incidence of fractures).\n-To increase bone mass in men with osteoporosis.\n-Treatment of glucocorticoid-induced osteoporosis in men and women who are either initiating or continuing systemic glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and are expected to remain on glucocorticoids for at least 12 months.\nUsual Adult Dose for Prevention of Osteoporosis:\n5 mg IV infusion over no less than 15 minutes, every 2 years\nUses:\n-Prevention of osteoporosis in postmenopausal women.\n-Prevention of glucocorticoid-induced osteoporosis in men and women who are either initiating or continuing systemic glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and are expected to remain on glucocorticoids for at least 12 months.\n Detailed Reclast dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Reclast injection.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Zoledronic acid can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve).\nOther drugs may interact with zoledronic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Reclast drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Reclast: hives; wheezing, chest tightness, trouble breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nnew or unusual pain in your thigh or hip;\njaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work;\nsevere joint, bone, or muscle pain;\nkidney problems - little or no urination, swelling in your feet or ankles, feeling tired;\nlow red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or\nlow calcium levels - muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).\nSerious side effects on the kidneys may be more likely in older adults.\nCommon Reclast side effects may include:\ntrouble breathing;\nnausea, vomiting, diarrhea, constipation;\nbone pain, muscle or joint pain;\nfever or other flu symptoms;\ntiredness;\neye pain or swelling;\npain in your arms or legs;\nheadache; or\nanemia.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Reclast side effects (more detail)\n','Reclast (zoledronic acid) (sometimes called zoledronate) is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.\nReclast is used to treat or prevent osteoporosis caused by menopause, or steroid use. This medicine also increases bone mass in men with osteoporosis. Reclast is for use when you have a high risk of bone fracture.\nReclast is also used to treat Paget\'s disease of bone.\nZometa is another brand of zoledronic acid used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). This medicine also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body. You should not use Reclast and Zometa at the same time.\n','Zoledronic acid may harm an unborn baby. Do not use Reclast if you are pregnant. Use effective birth control, and ask your doctor how long to prevent pregnancy after you stop this medicine.\nReclast can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine, or if you already have kidney disease. Call your doctor if you urinate less than usual, if you have swelling in your feet or ankles, or if you feel tired or short of breath.\nAlso call your doctor if you have muscle spasms, numbness or tingling (in hands and feet or around the mouth), new or unusual hip pain, or severe pain in your joints, bones, or muscles.\nYour doctor may recommend you have a dental exam for preventive tooth and gum care before you start your treatment with zoledronic acid. This is especially important if you have cancer, if you are undergoing chemotherapy or using steroids, or if you have poor dental health.\nSome people using medicines similar to Reclast have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and pre-existing dental problems.\nBefore taking this medicine\nYou should not be treated with Reclast if you are allergic to zoledronic acid.\nYou also should not receive Reclast if you have:\nlow levels of calcium in your blood (hypocalcemia); or\nsevere kidney disease.\nYou should not be treated with Reclast if are currently using any other bisphosphonate (such as alendronate, etidronate, ibandronate, pamidronate, risedronate, or tiludronate).\nTo make sure Reclast is safe for you, tell your doctor if you have ever had:\nkidney disease;\nhypocalcemia;\nthyroid or parathyroid surgery;\nsurgery to remove part of your intestine;\nasthma caused by taking aspirin;\nany condition that makes it hard for your body to absorb nutrients from food (malabsorption);\na dental problem (you may need a dental exam before you receive Reclast);\nif you are dehydrated; or\nif you take a diuretic or \"water pill\".\nZoledronic acid can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine, or if you already have kidney disease.\nThis medicine may cause jaw bone problems (osteonecrosis). The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Ask your doctor about your own risk.\nYou may need to have a negative pregnancy test before starting treatment with Reclast.\nDo not use Reclast if you are pregnant. Zoledronic acid may harm an unborn baby or cause birth defects. Zoledronic acid can remain in your body for weeks or years after your last dose. Use effective birth control to prevent pregnancy while using this medicine. Talk with your doctor about the need to prevent pregnancy after you stop using Reclast.\nThis medicine may affect fertility (ability to have children) in women. However, it is important to use birth control to prevent pregnancy because zoledronic acid can harm an unborn baby.\nYou should not breastfeed while using Reclast.\nHow is Reclast given?\nReclast is given as an infusion into a vein. A healthcare provider will give you this injection.\nReclast is sometimes given as a single dose only one time. It may also be given once every 1 or 2 years. How often you receive Reclast will depend on why you are using this medicine. Follow your doctor\'s instructions.\nDrink at least 2 glasses of water within a few hours before your injection to keep from getting dehydrated.\nYou may need frequent medical tests to help your doctor determine how long to treat you with Reclast. Your kidney function may also need to be checked.\nPay special attention to your dental hygiene while using Reclast. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Reclast.\nReclast is only part of a complete program of treatment that may also include diet changes and taking calcium and vitamin supplements. Follow your doctor\'s instructions very closely.\nYour doctor will determine how long to treat you with this medicine. Reclast is often given for only 3 to 5 years.\n','Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.\nAvoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.\n'),(744,'reglan','Usual Adult Dose of Reglan for Gastroesophageal Reflux Disease:\nOral: 10 to 15 mg up to 4 times a day 30 minutes before meals and at bedtime, depending upon symptoms being treated and clinical response. Therapy should not exceed 12 weeks.\nUsual Adult Dose of Reglan for Gastroparesis:\nDuring the earliest manifestations of diabetic gastric stasis, oral administration may be initiated. If severe symptoms are present, therapy should begin with IM or IV administration for up to 10 days until symptoms subside at which time the patient can be switched to oral therapy. Since diabetic gastric stasis is often recurrent, therapy should be reinstituted at the earliest manifestation.\nOral: 10 mg 4 times daily, 30 minutes before meals and at bedtime, for 2 to 8 weeks depending on clinical response.\n Detailed Reglan dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include drowsiness, confusion, or uncontrolled muscle movements.\n','Using Reglan with other drugs that make you drowsy can worsen this effect. Ask your doctor before you take opioid pain medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.\nTell your doctor about all your current medicines. Many drugs can interact with metoclopramide, especially:\ncyclosporine (Gengraf, Neoral, Sandimmune);\ndigoxin (digitalis, Lanoxin);\nglycopyrrolate (Robinul);\ninsulin;\nlevodopa (Larodopa, Atamet, Parcopa, Sinemet);\nmepenzolate (Cantil);\ntetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap);\natropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);\nbladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);\nblood pressure medications;\nbronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);\nirritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), or propantheline (Pro-Banthine);\nan MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate); or\nmedicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (Clozaril, FazaClo), haloperidol (Haldol), olanzapine (Zyprexa, Symbyax), prochlorperazine (Compazine), risperidone (Risperdal), thiothixene (Navane), and others.\nThis list is not complete and there are many other drugs that can interact with metoclopramide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Reglan drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Reglan: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop taking Reglan and call your doctor at once if you have any of these SIGNS OF A SERIOUS MOVEMENT DISORDER, which may occur within the first 2 days of treatment:\ntremors or shaking in your arms or legs;\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or\nany new or unusual muscle movements you cannot control.\nCall your doctor at once if you have:\nconfusion, depression, thoughts of suicide or hurting yourself;\nslow or jerky muscle movements, problems with balance or walking;\nmask-like appearance in your face;\na seizure;\nanxiety, agitation, jittery feeling, trouble staying still, trouble sleeping;\nswelling, feeling short of breath, rapid weight gain; or\nsevere nervous system reactionvery stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.\nCommon Reglan side effects may include:\nfeeling restless;\nfeeling drowsy or tired;\nlack of energy;\nnausea, vomiting;\nheadache, confusion; or\nsleep problems (insomnia).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Reglan side effects (more detail)\n','Reglan (metoclopramide) increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines and may help with nausea.\nReglan is used for 4 to 12 weeks to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief.\nReglan is also used to treat gastroparesis (slow stomach emptying) in people with diabetes, which can cause heartburn and stomach discomfort after meals.\nReglan may also be used for purposes not listed in this medication guide.\n','Do not use Reglan if you\'ve ever had muscle movement problems after using metoclopramide or similar medicines, or if you\'ve had a movement disorder called tardive dyskinesia. You also should not use this medicine if you\'ve had stomach or intestinal problems (a blockage, bleeding, or a hole or tear), epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma).\nNEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).\nBefore you take Reglan, tell your doctor if you have kidney or liver disease, congestive heart failure, high blood pressure, diabetes, Parkinson\'s disease, or a history of depression.\nDo not drink alcohol. It can increase some of the side effects of metoclopramide.\nStop using Reglan and call your doctor at once if you have tremors or uncontrolled muscle movements, fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing, depressed mood, thoughts of suicide or hurting yourself, hallucinations, anxiety, agitation, seizure, or jaundice (yellowing of your skin or eyes).\nBefore taking this medicine\nYou should not use Reglan if you are allergic to metoclopramide, or if you have:\ntardive dyskinesia (a disorder of involuntary movements);\nstomach or intestinal problems such as a blockage, bleeding, or perforation (a hole or tear in your stomach or intestines);\nepilepsy or other seizure disorder;\nan adrenal gland tumor (pheochromocytoma); or\nif you\'ve ever had muscle movement problems after using metoclopramide or similar medicines.\nTell your doctor if you have ever had:\nliver or kidney disease;\nproblems with muscle movements;\ncongestive heart failure or a heart rhythm disorder;\nhigh blood pressure;\nseizures;\nbreast cancer;\nParkinson\'s disease;\ndiabetes; or\ndepression or mental illness.\nTell your doctor if you are pregnant before taking metoclopramide.\nIt may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.\nReglan is not FDA-approved for use by anyone younger than 18 years old.\nHow should I use Reglan?\nTake Reglan exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Use the medicine exactly as directed.\nReglan should be taken for only 4 to 12 weeks.\nNEVER USE REGLAN IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use of metoclopramide can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).\nReglan is usually taken 30 minutes before meals and at bedtime, or only with meals that usually cause heartburn. Follow your doctor\'s dosing instructions very carefully.\nDo not use two different forms of metoclopramide (such as tablets and oral syrup) at the same time.\nStore at room temperature in a tightly-closed container, away from moisture and heat. Keep the bottle tightly closed.\nAfter you stop taking Reglan, you may have unpleasant withdrawal symptoms such as headache, dizziness, or nervousness.\n','Drinking alcohol with this medicine can cause side effects.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\nDo not take Reglan with other medications that increase the risk of experiencing extrapyramidal reactions (eg, spasms, muscle contractions, jerky/rigid movements).\n'),(745,'relafen','Usual Adult Dose for Osteoarthritis:\nInitial: 1000 mg orally once a day at bedtime.\nMaintenance: 1500 to 2000 mg orally in 1 to 2 divided doses, to a maximum daily dose of 2000 mg.\nUsual Adult Dose for Rheumatoid Arthritis:\nInitial: 1000 mg orally once a day at bedtime.\nMaintenance: 1500 to 2000 mg orally in 1 to 2 divided doses, to a maximum daily dose of 2000 mg.\n Detailed Relafen dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Ask your doctor before using Relafen if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.\nTell your doctor about all your current medicines and any you start or stop using, especially:\nlithium;\nmethotrexate;\na blood thinner (examples: warfarin, Coumadin, Jantoven, apixaban, dabigatran, rivaroxaban);\nheart or blood pressure medication, including a diuretic or \"water pill\"; or\nsteroid medicine (such as prednisone).\nThis list is not complete. Other drugs may interact with nabumetone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Relafen drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Relafen: (hives, sneezing, runny or stuffy nose, wheezing, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nGet emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.\nStop using Relafen and call your doctor at once if you have:\nshortness of breath (even with mild exertion);\nswelling or rapid weight gain;\nthe first sign of any skin rash, no matter how mild;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;\nliver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nkidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or\nlow red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.\nCommon Relafen side effects may include:\nstomach pain, indigestion, nausea;\ndiarrhea, constipation, gas;\nswelling in your hands and feet;\nheadache, dizziness;\nitching, skin rash; or\nringing in your ears.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Relafen side effects (more detail)\n','Relafen (nabumetone) is a nonsteroidal anti-inflammatory drug (NSAID). Nabumetone works by reducing hormones that cause inflammation and pain in the body.\nRelafen is used to relieve the symptoms of rheumatoid arthritis or osteoarthritis.\nRelafen may also be used for purposes not listed in this medication guide.\n','Relafen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nRelafen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Relafen, especially in older adults.\nCall your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.\nDo not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Relafen (such as ibuprofen, ketoprofen, or naproxen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, ketoprofen, or naproxen. Do not drink alcohol while taking Relafen. Alcohol can increase the risk of stomach bleeding caused by nabumetone. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Relafen can make your skin more sensitive to sunlight and sunburn may result.\nBefore taking this medicine\nRelafen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.\nDo not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).\nRelafen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Relafen, especially in older adults.\nYou should not use Relafen if you are allergic to nabumetone, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.\nTo make sure Relafen is safe for you, tell your doctor if you have ever had:\nheart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;\na heart attack, stroke, or blood clot;\nstomach ulcers or bleeding;\nasthma;\nliver or kidney disease; or\nfluid retention.\nIf you are pregnant, you should not take Relafen unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.\nRelafen is not FDA-approved for use by anyone younger than 18 years old.\nHow should I take Relafen?\nTake Relafen exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger amounts or for longer than recommended. Use the lowest dose that is effective in treating your condition.\nYou may take Relafen with or without food.\nIf you use this medicine long-term, you may need frequent medical tests.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\n','Avoid drinking alcohol and smoking. It may increase your risk of stomach bleeding.\nAsk a doctor or pharmacist before using any cold, allergy, or pain medication. Many medicines available over the counter contain aspirin or other medicines similar to Relafen. Taking certain products together can cause you to get too much of this type of medication. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, or naproxen.\nAvoid exposure to sunlight or tanning beds. Relafen can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.\n'),(746,'relugolix','Usual Adult Dose for Prostate Cancer:\nLoading Dose: 300 mg orally once on the first dayMaintenance Dose: 120 mg orally once a day Comment:-Treatment is usually continued upon development of nonmetastatic or metastatic castration-resistant prostate cancer in patients treated with GnRH receptor agonists and antagonists.Use: For the treatment of adult patients with advanced prostate cancer\n Detailed Relugolix dosage information\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nCertain other drugs should not be used within 6 hours after you take relugolix. Your relugolix dose should be taken first, before the other medicine. Carefully follow your doctor\'s instructions about how to schedule the doses of all your medicines.\nOther drugs may affect relugolix, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Relugolix drug interactions (more detail)\nDoes Relugolix interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nfast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);\nchest pain or pressure;\nsudden numbness or weakness on one side of the body;\nlittle or no urination, pain or burning when you urinate;\nbreast pain or swelling;\ndepressed mood; or\nunusual bleeding.\nCommon side effects may include:\nflushing (sudden warmth, redness, or tingly feeling);\nfeeling tired;\nweight gain;\nimpotence, sexual problems;\ndiarrhea, constipation;\nmuscle or joint pain; or\nabnormal lab tests.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n','Relugolix is used to treat advanced prostate cancer.\nRelugolix may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nRelugolix is not for use in women or children.\nTell your doctor if you have ever had:\nheart problems; or\nlong QT syndrome (in you or a family member).\nUse effective birth control if your sex partner is pregnant or able to get pregnant. Relugolix can harm an unborn baby if the father is using  relugolix. Keep using birth control for at least 2 weeks after your last dose of this medicine.\nThis medicine may affect fertility (your ability to have children). However, it is important to use birth control if your partner is pregnant or able to get pregnant because relugolix can harm an unborn baby.\nHow should I take relugolix?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nRelugolix is usually taken as 3 tablets the first day, followed by 1 tablet per day from then on.\nTake the medicine at the same time each day, with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nYou may need frequent blood tests. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).\nYour doctor will determine how long to treat you with relugolix. Do not change your dose or stop using this medicine without your doctor\'s advice.\nStore at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.\nKeep the bottle tightly closed when not in use.\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.\nIf you miss more than 7 daily doses, your doctor may want you to restart the medicine by taking 3 tablets the first day and 1 daily tablet thereafter.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(747,'remdesivir','Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using remdesivir.\nRemdesivir is given as an infusion into a vein. A healthcare provider will give you this injection.\n remdesivir must be given slowly, and the infusion can take 30 to 120 minutes to complete.\nRemdesivir is usually given once per day for 5 to 10 days.\nYou will need frequent blood tests to check your liver function.\nYou must remain under the care of a doctor while you are being treated with remdesivir for COVID-19.\n Detailed Remdesivir dosage information\nWhat happens if I miss a dose?\nBecause you will receive remdesivir in a clinical setting, you are not likely to miss a dose.\nWhat happens if I overdose?\nSince  remdesivir is given by a healthcare professional in a medical setting, you will be treated quickly if an overdose occurs.\n','Tell your doctor if you also take chloroquine or hydroxychloroquine. Either of these other medicines could make remdesivir less effective.\nOther drugs may affect remdesivir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Remdesivir drug interactions (more detail)\nDoes Remdesivir interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome side effects may occur during or after the injection. Tell your caregiver right away if you have:\nsevere headache, pounding in your neck or ears;\nfast, slow, or pounding heartbeats;\nwheezing, trouble breathing;\nswelling in your face;\nnausea;\nfever, chills, or shivering;\nitching, sweating; or\na light-headed feeling, like you might pass out;\nCommon side effects may include:\nnausea; or\nabnormal liver function tests.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Remdesivir side effects (more detail)\n','Remdesivir is used to treat people with coronavirus disease 2019 (COVID-19) who are in a hospital.\nRemdesivir is for use in adults and children at least 12 years old and weighing at least 88 pounds (40 kilograms).\nRemdesivir may also be used for purposes not listed in this medication guide.\n','Remdesivir is for use only in people with COVID-19 who are in a hospital. You must remain under the care of a doctor while receiving  remdesivir.\nBefore taking this medicine\nYou should not be treated with remdesivir if you are allergic to it.\nTell your doctor if you have ever had:\nliver disease; or\nkidney disease.\nTell your doctor if you are pregnant or plan to become pregnant, or if you are breastfeeding.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(748,'remeron','Usual Adult Dose for Depression:\nInitial dose: 15 mg orally once a day at bedtime\nMaintenance dose: 15 to 45 mg orally once a day\nMaximum dose: 45 mg/day\nComments:\n-May increase the dose every 1 to 2 weeks to a maximum 45 mg/day according to patient response.\n-Patients should be periodically reassessed to determine the need for continued use of this drug.\nUse: Treatment of major depressive disorder\n Detailed Remeron dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include confusion, memory problems, drowsiness, and fast heart rate.\n','Using Remeron with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your current medicines. Many drugs can interact with mirtazapine, especially:\ncimetidine;\ndiazepam;\nSt. John\'s wort;\ntramadol;\ntryptophan (sometimes called L-tryptophan);\nan antibiotic - clarithromycin, rifampin, rifampicin, telithromycin;\nantifungal medicine - itraconazole, ketoconazole;\nantiviral medicine to treat HIV/AIDS - indinavir, nelfinavir, ritonavir, saquinavir;\nmedicine to treat mood disorders, thought disorders, or mental illness - such as lithium, other antidepressants, or antipsychotics;\nmigraine headache medicine - sumatriptan, rizatriptan, Imitrex, Maxzalt, and others; or\nseizure medicine - carbamazepine, phenytoin.\nThis list is not complete and many Other drugs may interact with mirtazapine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Remeron drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Remeron (hives, joint pain, fever, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nracing thoughts, decreased need for sleep, unusual risk-taking behavior, feelings of extreme happiness or sadness, being more talkative than usual;\nblurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;\na light-headed feeling, like you might pass out;\nsevere rash, blisters, or swelling on the palms of your hands or the soles of your feet;\na seizure;\nlow white blood cell counts - fever, chills, sore throat, cough, sores in your mouth or nose, flu-like symptoms, trouble breathing; or\nlow sodium level - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nCommon Remeron side effects include:\ndrowsiness, dizziness;\nincreased appetite; or\nweight gain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Remeron side effects (more detail)\n','Remeron (mirtazapine) is an antidepressant. The way mirtazapine works is still not fully understood. It is thought to positively affect communication between nerve cells in the central nervous system and/or restore chemical balance in the brain.\nRemeron is prescription medicine used to treat a certain type of depression called Major Depressive Disorder (MDD) in adults.\nIt is not known if Remeron is safe and effective for use in treating MDD in children.\n','You should not take Remeron if you are also taking tryptophan (sometimes called L-tryptophan).\nDo not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine and others.\nSome people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Remeron. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nDo not give this medicine to anyone younger than 18 years old without the advice of a doctor. Mirtazapine is not approved for use in children.\nIt may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.\nDrinking alcohol can increase certain side effects of mirtazapine.\nRemeron may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\nDo not stop taking mirtazapine abruptly. Talk to your doctor before stopping mirtazapine.\nBefore taking this medicine\nYou should not take Remeron if you are allergic to mirtazapine or any of the ingredients in Remeron or Remeron SolTab.\nDo not use Remeron if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.\nTo make sure Remeron is safe for you, tell your doctor if you have ever had:\nlow white blood cell counts;\nglaucoma;\nliver or kidney disease;\nlow sodium levels in your blood;\na seizure;\ndepression, suicidal thoughts or actions;\nbipolar disorder (manic depression) in you or a family member;\nheart problems or stroke;\nhigh cholesterol or triglycerides;\nlong QT syndrome (in you or a family member); or\nlow blood pressure.\nBe sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with mirtazapine and cause a serious condition called serotonin syndrome.\nSome young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nTell your doctor if you are pregnant or breastfeeding.\nThe orally disintegrating tablet may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).\nRemeron is not approved for use by anyone younger than 18 years old.\nHow should I take Remeron?\nTake Remeron exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nTake the medicine at the same time each day, usually at bedtime.\nTake the regular Remeron tablet with water.\nYou may take this medicine with or without food.\nRemove a Remeron SolTab orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.\nIt may take a few weeks for your symptoms to improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.\nDo not stop using Remeron suddenly, or you could have unpleasant symptoms (such as dizziness, vomiting, agitation, sweating, confusion, numbness, tingling, or electric shock feelings). Ask your doctor how to safely stop using this medicine.\nStore at room temperature away from moisture, heat, and light.\n','Drinking alcohol with this medicine can cause side effects.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(749,'remicade','Before you start treatment with Remicade, your doctor may perform tests to make sure you do not have tuberculosis or other infections.\nRemicade is given as an infusion into a vein. A healthcare provider will give you this injection.\nThis medicine must be given slowly, and the infusion can take at least 2 hours to complete.\nYou may be watched closely after receiving infliximab, to make sure the medicine has not caused any serious side effects.\nInfliximab affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis, and you may need frequent TB tests.\nSerious infections may be more likely in older adults.\nIf you need surgery, tell the surgeon ahead of time that you are using Remicade.\nIf you\'ve ever had hepatitis B, using infliximab can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.\n Detailed Remicade dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss an appointment for your Remicade injection.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\nabatacept;\nanakinra;\ntocilizumab;\nany \"biologic\" medications to treat your condition - adalimumab, certolizumab, etanercept, golimumab, natalizumab, rituximab, and others; or\nany other medicines to treat Crohn\'s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis.\nThis list is not complete. Other drugs may interact with infliximab, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Remicade drug interactions (more detail)\n','Some side effects may occur during the injection. Tell your caregiver if you feel dizzy, nauseated, light-headed, itchy or tingly, short of breath, or have a headache, fever, chills, muscle or joint pain, pain or tightness in your throat, chest pain, or trouble swallowing during the injection. Infusion reactions may also occur within 1 or 2 hours after injection.\nGet emergency medical help if you have signs of an allergic reaction to Remicade: hives; chest pain, difficult breathing; fever, chills, severe dizziness; swelling of your face, lips, tongue, or throat.\nSerious and sometimes fatal infections may occur during treatment with Remicade. Call your doctor right away if you have signs of infection such as: fever, extreme tiredness, flu symptoms, cough, or skin symptoms (pain, warmth, or redness).\nAlso call your doctor if you have:\nskin changes, new growths on the skin;\npale skin, easy bruising or bleeding;\ndelayed allergic reaction (up to 12 days after receiving Remicade) - fever, sore throat, trouble swallowing, headache, joint or muscle pain, skin rash, or swelling in your face or hands;\nliver problems - right-sided upper stomach pain, loss of appetite, yellowing of your skin or eyes (jaundice), and not feeling well;\nlupus-like syndrome - joint pain or swelling, chest discomfort, feeling short of breath, skin rash on your cheeks or arms (worsens in sunlight);\nnerve problems - numbness or tingling, problems with vision, weakness in your arms or legs, seizure;\nnew or worsening psoriasis - skin redness or scaly patches, raised bumps filled with pus;\nsigns of heart failure - shortness of breath with swelling of your ankles or feet, rapid weight gain;\nsigns of a stroke - sudden numbness or weakness, trouble speaking or understanding what is said to you, problems with vision or balance, severe headache;\nsigns of lymphoma - fever, night sweats, weight loss, stomach pain or swelling, chest pain, cough, trouble breathing, swollen glands (in your neck, armpits, or groin); or\nsigns of tuberculosis - fever, cough, night sweats, loss of appetite, weight loss, feeling constantly tired.\nSerious infections may be more likely in adults who are 65 years or older.\nCommon Remicade side effects may include:\nstuffy nose, sinus pain;\nfever, chills, sore throat;\ncough, chest pain, shortness of breath;\nhigh or low blood pressure;\nheadache, feeling light-headed;\nrash, itching; or\nstomach pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Remicade side effects (more detail)\n','Remicade (infliximab) reduces the effects of a substance in the body that can cause inflammation.\nRemicade is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and severe or disabling plaque psoriasis in adults.\nRemicade is also used to treat ulcerative colitis and Crohn\'s disease in adults and children at least 6 years old.\nInfliximab is often used when other medicines have not been effective.\n','You should not use Remicade if you are allergic to infliximab, or if you are also being treated with anakinra (Kineret) or abatacept (Orencia).\nUsing Remicade may increase your risk of developing certain types of cancer, including a rare fast-growing type of lymphoma that can be fatal. Ask your doctor about your specific risk.\nRemicade affects your immune system. You may get infections more easily, even serious or fatal infections. Before you start using Remicade, your doctor may perform tests to make sure you do not have certain infections. Call your doctor if you have a fever, tiredness, flu symptoms, cough, or skin pain.\nBefore taking this medicine\nTell your doctor if you have ever had tuberculosis (TB), or anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.\nTo make sure Remicade is safe for you, tell your doctor if you have ever had:\nheart failure or other heart problems;\nan active infection (fever, cough, flu symptoms, open sores or skin wounds);\ndiabetes;\nliver failure, hepatitis B, or other liver problems;\nchronic obstructive pulmonary disease (COPD);\nheart problems;\ncancer;\na weak immune system;\nseizures;\nnumbness or tingling anywhere in your body;\na nerve-muscle disorder, such as multiple sclerosis or Guillain-Barré syndrome;\nphototherapy for psoriasis;\nvaccination with BCG (Bacille Calmette-Guérin); or\nif you are scheduled to receive any vaccines.\nMake sure your child is current on all vaccines before he or she starts treatment with Remicade.\nRemicade may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn\'s disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of lymphoma. Talk with your doctor about your own risk.\nRemicade may cause other types of cancer, such as skin cancer or cancer of the cervix. Ask your doctor about this risk.\nIf you use infliximab while you are pregnant, make sure any doctor caring for your new baby knows that you used the medicine during pregnancy. Being exposed to infliximab in the womb could affect your baby\'s vaccination schedule during the first 6 months of life.\nYou should not breastfeed while you are receiving infliximab.\nRemicade is not for use in children younger than 6 years old.\n','Avoid activities that may increase your risk of bleeding injury.\nDo not receive a \"live\" vaccine while using infliximab, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).\n'),(750,'renvela','Usual Adult Dose for Hyperphosphatemia of Renal Failure:\nInitial Dosing for patients not on a phosphate binder: 800 mg to 1600 mg orally 3 times a day with meals.\nBased on serum phosphorus level:\n-Phosphorus greater than 5.5 to less than 7.5 mg/dL: 800 mg 3 times a day with meals\n-Phosphorus greater than or equal to 7.5 to less than 9 mg/dL: 1200 to 1600 mg 3 times a day with meals\n-Phosphorus greater than or equal to 9 mg/dL: 1600 mg 3 times a day with meals\n-Titrate in increments of 800 mg 3 times a day at 2-week intervals with the goal of controlling serum phosphorus within target range.\nAverage prescribed dose: 7.2 g/day (2.4 g with each meal)\nMaximum studied dose: 14 g per day (carbonate); 13 g per day (hydrochloride)\nSwitching from the hydrochloride salt to carbonate: Use the same dose, however further titration may be necessary to achieve desired phosphorus levels.\nSwitching from calcium acetate: Substitute approximately mg for mg\nComment: Treatment of hyperphosphatemia includes reduction in dietary intake of phosphate, inhibition of intestinal phosphate absorption with phosphate binders, and removal of phosphate with dialysis.\nUse: To control serum phosphorus levels in patients with chronic kidney disease on dialysis.\n Detailed Renvela dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Be sure to take the missed dose with food. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with Renvela, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Renvela drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Renvela: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using Renvela and call your doctor at once if you have:\nchoking, or trouble swallowing;\nblack, bloody, or tarry stools;\nsevere constipation with stomach pain; or\nconstipation that gets worse or does not clear up.\nCommon Renvela side effects may include:\nnausea, vomiting, stomach pain, loss of appetite;\nupset stomach, gas, bloating;\ndiarrhea, constipation;\ntired feeling;\nitching; or\njoint pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Renvela side effects (more detail)\n','Renvela (sevelamer) is a phosphate binder. Sevelamer helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus.\nRenvela is used to control phosphorus levels in people with chronic kidney disease who are on dialysis.\nRenvela may also be used for purposes not listed in this medication guide.\n','You should not take Renvela if you have a bowel obstruction.\nBefore taking Renvela, tell your doctor if you have severe constipation, a blockage in your intestines, a stomach or intestinal disorder, trouble swallowing, or if you have recently had stomach or intestinal surgery.\nAvoid taking any other medicines within 1 hour before or 3 hours after you take Renvela. Sevelamer can bind to other medications and make them less effective.\nBefore taking this medicine, tell your doctor if you are taking ciprofloxacin (Cipro), a heart rhythm medication, or a seizure medication.\nDo not take calcium or other mineral supplements without your doctor\'s advice. Use only the specific type of calcium or mineral supplement your doctor recommends.\nBefore taking this medicine\nYou should not take Renvela if you are allergic to sevelamer, or if you have a bowel obstruction.\nTo make sure Renvela is safe for you, tell your doctor if you have:\ntrouble swallowing;\nsevere constipation;\na blockage in your intestines;\nslow digestion;\na stomach or intestinal disorder; or\nif you have recently had stomach or intestinal surgery.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Your dose needs may be different during pregnancy.\nTaking Renvela while you are pregnant can lower your blood levels of certain vitamins or folic acid. Follow your doctor\'s instructions about taking vitamins or mineral supplements during pregnancy.\nBecause sevelamer is not absorbed into the bloodstream, it is not expected to be harmful to a nursing baby.\nRenvela is not approved for use by anyone younger than 6 years old.\nHow should I take Renvela?\nTake Renvela exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nTake Renvela with meals.\nRenvela powder must be dissolved in water before you take it. The 0.8-gram packet should be mixed with at least 1 ounce (2 tablespoons) of water. The 2.4-gram packet should be mixed with at least 2 ounces (4 tablespoons) of water.\nStir the powder in water until it is completely dissolved. Stir and drink this mixture right away. To get the entire dose, add a little more water to the same glass, swirl gently and drink right away.\nWhile using sevelamer, you may need frequent blood tests.\nCall your doctor if you have have trouble swallowing the tablet, or if it feels like it gets stuck in your esophagus after you swallow it.\nRenvela may be only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must eat or avoid to help control your condition.\nStore at room temperature away from moisture and heat.\n','You may be taking other medicines that should not be taken at the same time. Taking Renvela can make it harder for your body to absorb certain drugs, making them less effective:\nciprofloxacin (Cipro) should be taken at least 2 hours before or 6 hours after you take Renvela;\nmycophenolate mofetil (CellCept) should be taken at least 2 hours before you take Renvela.\n'),(751,'repaglinide','Usual Adult Dose for Diabetes Type 2:\nIndividualize therapy: Dose preprandially 2, 3, or 4 times a day-For patients not previously treated with antidiabetic agents or whose glycosylated hemoglobin (HbA1c) is less than 8%:Initial dose: 0.5 mg orally with each meal -For patients previously treated with antidiabetic agents or whose HbA1c is 8% or higher:Initial dose: 1 or 2 mg orally with each meal Dose Adjustments: Based upon blood glucose response, double the preprandial dose up to a maximum meal time dose of 4 mg until satisfactory glycemic response is achieved; allow at least 1 week to assess response after each dose adjustment.  Recommended Dose Range: 0.5 to 4 mg orally with each mealMaximum Daily Dose: 16 mg per day Comments:-Fasting blood glucose concentrations are generally used to adjust doses, however, postprandial glucose levels may be used in patients whose pre-meal blood glucose levels are satisfactory but whose overall glycemic control (HbA1c) is inadequate.  -When hypoglycemia occurs in patients taking this drug in combination with a thiazolidinedione or metformin, the dose of this drug should be reduced.  Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.\n Detailed Repaglinide dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Many other medicines that can increase or decrease the effects of repaglinide on lowering your blood sugar. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Repaglinide drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nCall your doctor at once if you have:\npale or yellowed skin, dark colored urine, fever, confusion or weakness; or\npancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting.\nCommon side effects may include:\nlow blood sugar;\nnausea, diarrhea;\nheadache, back pain;\njoint pain; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Repaglinide side effects (more detail)\n','Repaglinide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.  repaglinide is not for treating type 1 diabetes.\nRepaglinide may also be used for purposes not listed in this medication guide.\n','You should not use repaglinide if you have type 1 diabetes, severe liver disease, or diabetic ketoacidosis.\nYou should not use repaglinide together with gemfibrozil or NPH insulin (such as isophane insulin).\nBefore taking this medicine\nYou should not use repaglinide if you are allergic to it, or if you have:\nsevere liver disease; or\ndiabetic ketoacidosis (call your doctor for treatment).\nMany drugs can interact with repaglinide and some drugs should not be used at the same time. Your doctor may change your treatment plan if you also use:\nclopidogrel;\ncyclosporine;\ngemfibrozil; or\nNPH insulin (such as isophane insulin).\nTell your doctor if you have ever had:\nliver disease; or\nif you also take metformin or other diabetes medicines.\nFollow your doctor\'s instructions about using  repaglinide if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nYou should not breastfeed while using repaglinide.\nRepaglinide is not approved for use by anyone younger than 18 years old.\nHow should I take repaglinide?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nRepaglinide is usually taken 2 to 4 times daily, within 30 minutes before eating a meal. Follow your doctor\'s instructions. If you skip a meal, do not take your dose of repaglinide. Wait until your next meal.\nYour blood sugar will need to be checked often, and you may need other blood tests at your doctor\'s office.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nRepaglinide is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore repaglinide at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake your dose as soon as you can, but only if you are getting ready to eat a meal. If you skip a meal, skip the missed dose and wait until your next meal.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. A repaglinide overdose can cause life-threatening hypoglycemia.\nSymptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).\n','Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.\n'),(752,'repatha','Usual Adult Dose of Repatha for Hyperlipidemia:\n-140 mg subcutaneously every 2 weeks, or\n-420 mg subcutaneously once a month\nComments:\n-When switching dosage regimens, administer the first dose of the new regimen on the next scheduled date of prior regimen.\n-This drug should not be used in patients without familial hypercholesterolemia or atherosclerotic cardio vascular disease.\nUses: Adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease requiring additional lowering of low density lipoprotein cholesterol (LDL-C)\nUsual Adult Dose of Repatha for Homozygous Familial Hypercholesterolemia:\n-420 mg subcutaneously once a month\nComments:\n-Measure LDL-C levels every 4 to 8 weeks after starting this drug.\n-Response to therapy depends on the degree of LDL-receptor function.\nUses: Adjunct to diet and other LDL-lowering therapies (e.g., statins, ezetimibe, LDL apheresis) for the treatment of patients with homozygous familial hypercholesterolemia (HoFH) requiring additional lowering of LDL-C\n Detailed Repatha dosage information\nWhat happens if I miss a dose?\nUse the missed dose within 7 days after that injection was due. Skip the missed dose if you are more than 7 days late for the injection. After a missed dose, go back to your original schedule and use the medicine again when your next scheduled dose is due.\nDo not use extra medicine to make up a missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with evolocumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n','Get emergency medical help if you have signs of an allergic reaction to Repatha: hives, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor.\nCommon Repatha side effects may include:\nredness, pain, or bruising where an injection was given;\nback pain;\nflu symptoms; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Repatha side effects (more detail)\n','Repatha (evolocumab) is a human monoclonal antibody. It works by helping the liver reduce levels of \"bad\" cholesterol (low-density lipoprotein, or LDL) circulating in your blood.\nRepatha is used together with a low-fat diet and other cholesterol-lowering medications in people with homozygous or heterozygous familial hypercholesterolemia (inherited types of high cholesterol). These conditions can cause high blood levels of LDL cholesterol, and can also cause plaque to build up inside your arteries.\nRepatha is also used to help lower the risk of stroke, heart attack, or other heart complications in people with heart or blood vessel problems caused by plaque build-up or hardening in the arteries (also called atherosclerosis, or arteriosclerosis).\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use Repatha if you are allergic to evolocumab.\nTo make sure Repatha is safe for you, tell your doctor if you have ever had:\nliver or kidney disease; or\na latex allergy.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of evolocumab on the baby.\nIt may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.\nDo not give Repatha to a child without medical advice. Evolocumab is not approved for use by anyone younger than 13 years old. For certain conditions, Repatha should not be given to a child of any age.\nHow is Repatha given?\nUse Repatha exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nRepatha is injected under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.\nRepatha is usually given once a month, or once every 2 weeks. Depending on your dose amount, you may need to use up to 3 separate injections at one time. Follow your doctor\'s dosing instructions very carefully.\nRepatha is available in a prefilled syringe, a SureClick prefilled autoinjector, or a Pushtronex on-body infusor with prefilled cartridge. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions about your injection device, or call the manufacturer at 1-844-737-2842.\nIt may take up to 15 seconds to inject this medicine using a prefilled syringe or a SureClick autoinjector. If you use more than one injection at a time, be sure to finish all injections within 30 minutes.\nThe Pushtronex on-body infusor is a special hands-free device placed on the skin that delivers your evolocumab dose slowly. Read and carefully follow all instructions for using this product. You will need to wear the device for about 9 minutes to get the full dose. While wearing the on-body infusor, you may perform moderate activities such as walking, bending, or reaching.\nYour care provider will show you the best places on your body to inject Repatha or place the on-body infusor. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nEach single-use prefilled syringe, cartridge, or injection device is for one use only. Throw away after one use, even if there is still some medicine left inside. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof \"sharps\" container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.\nStore Repatha in the refrigerator in its original carton and protect from light and heat. Do not freeze. Throw away any medicine that has been frozen.\nTake the medicine out of the refrigerator and allow it to reach room temperature for 30 to 45 minutes before injecting your dose. Do not heat a syringe or injection device.\nYou may also store Repatha in the original carton at cool room temperature, away from light and heat. Use the medicine within 30 days if it is kept at room temperature.\nHandle this medicine carefully. Dropping an injection device can cause it to break. Do not use an injection device that has been dropped onto a hard surface, even if you cannot see a break in it. Call your pharmacist for new medicine.\nDo not shake this medicine. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.\nYou should not stop using Repatha without your doctor\'s advice, or your LDL cholesterol levels may increase.\nRepatha is only part of a complete treatment program that also includes diet, statin medication, and regular blood testing. Follow your doctor\'s instructions very closely.\n','Do not inject Repatha into skin that is bruised, sore, scarred, or hardened.\n'),(753,'requip','Usual Adult Dose of Requip for Parkinson\'s Disease:\nImmediate-release tablets:\nInitial: 0.25 mg orally three times daily\nAfter 1 week, the dose may be titrated up in weekly increments based on individual efficacy and tolerability:\nWeek 2: give 0.5 mg orally 3 times daily\nWeek 3: give 0.75 mg orally 3 times daily\nWeek 4: give 1 mg orally 3 times daily\nAfter week 4, increase by 1.5 mg/day on a weekly basis up to a dose of 9 mg/day, then increase by 3 mg/day on a weekly basis up to a maximum daily dose of 24 mg\nMaximum Dose: 8 mg orally three times a day\nExtended-release tablets:\nInitial: 2 mg orally once daily for 1 to 2 weeks, followed by increases of 2 mg/day at 1-week or longer intervals, depending on therapeutic response and tolerability\nMaximum dose: 24 mg orally once a day\nPatients may switch from immediate-release to extended-release: The initial dose of extended-release tablet should most closely match the total daily dose of immediate-release formulation. Following conversion, adjust dose depending on response and tolerability.\nComments:\n-If significant interruption in therapy occurs, retitration may be necessary; upon discontinuation, this drug should be gradually tapered over a 7-day period.\n-The extended-release tablet is designed to release medication over a 24-hour period, if rapid gastrointestinal transit occurs, and tablet residue is observed in the stool, there is a risk of incomplete release of medication,\nUse: For the treatment of Parkinson\'s disease.\nUsual Adult Dose for Restless Legs Syndrome:\nImmediate-release tablets:\nInitial: 0.25 mg orally once a day on Day 1 and Day 2\nDose titration: May titrate as follows based on individual efficacy and tolerability:\nDays 3 to 7: give 0.5 mg orally once a day\n-Week 2: give 1 mg orally once a day\n-Week 3: give 1.5 mg orally once a day\n-Week 4: give 2 mg orally once a day\n-Week 5: give 2.5 mg orally once a day\n-Week 6: give 3 mg orally once a day\n-Week 7: give 4 mg orally once a day\nMaximum Dose: 4 mg orally once a day\nComments:\n-Take 1 to 3 hours before bedtime.\n-In clinical trials, this drug was not tapered prior to discontinuation.\nUse: For the treatment of moderate to severe Restless Legs Syndrome.\n Detailed Requip dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Taking Requip with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication, muscle relaxer, or medicine for anxiety, depression, or seizures.\nOther drugs may interact with ropinirole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Requip drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Requip: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nSome people taking Requip have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.\nYou may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.\nCall your doctor at once if you have:\nextreme drowsiness, falling asleep suddenly (even after feeling alert);\nworsening or no improvement in your symptoms;\na light-headed feeling, like you might pass out;\nunusual changes in mood or behavior;\ntremors, twitching uncontrollable muscle movements; or\nhallucinations (seeing or hearing things that are not real).\nSide effects such as confusion or hallucinations may be more likely in older adults.\nCommon Requip side effects may include:\ndrowsiness, dizziness, weakness;\nheadache, confusion, hallucinations;\nincreased blood pressure (severe headache, pounding in your neck or ears, nosebleed, irregular heartbeats);\nnausea, vomiting, upset stomach, constipation;\nflu symptoms (fever, chills, body aches);\nsudden muscle movements;\nincreased sweating; or\nswelling in your legs or feet.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Requip side effects (more detail)\n','Requip (ropinirole) is a dopaminergic agent and it has some of the same effects as dopamine, a naturally occuring chemical found in your body. Low levels of dopamine in the brain are associated with Parkinson\'s disease.\nRequip is used to treat symptoms of Parkinson\'s disease (stiffness, tremors, muscle spasms, and poor muscle control). Ropinirole is also used to treat restless legs syndrome (RLS).\nOnly immediate-release Requip is approved to treat either Parkinson symptoms or RLS. Extended-release Requip XL is approved only to treat Parkinson symptoms.\nParkinson\'s and RLS are two separate disorders. Having one of these conditions will not cause you to have the other condition.\n','Requip may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.\nYou may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication. Talk with your doctor if you believe you have any intense or unusual urges while taking Requip.\nDo not share this medication with another person, even if they have the same symptoms you do. Avoid drinking alcohol, which can increase some of the side effects of Requip. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by ropinirole. Tell your doctor if you regularly use any of these other medicines.\nRequip may cause hallucinations (the sensation of hearing or seeing something that is not there), most commonly among elderly people. Call your doctor if you experience hallucinations.\nDo not stop using Requip or change your dose without first talking to your doctor. You may have side effects such as fever, muscle stiffness, and confusion if you stop the medication suddenly or if you change doses.\nSome people taking medicines for Parkinson\'s disease have developed skin cancer (melanoma). However, people with Parkinson\'s disease may have a higher risk than most people for developing melanoma. Talk to your doctor about your specific risk and what skin symptoms to watch for. You may need to have regular skin examinations.\nBefore taking this medicine\nYou should not use Requip if you are allergic to ropinirole.\nTo make sure Requip is safe for you, tell your doctor if you have:\nhigh or low blood pressure;\nkidney disease (or if you are on dialysis);\nheart disease, heart rhythm problems;\na sleep disorder such as narcolepsy, or other conditions that may cause daytime sleepiness; or\nif you smoke.\nPeople with Parkinson\'s disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.\nIt is not known whether Requip will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether ropinirole passes into breast milk or if it could affect the nursing baby. Ropinirole may slow breast milk production. Tell your doctor if you are breast-feeding.\nRequip is not approved for use by anyone younger than 18 years old.\nHow should I take Requip?\nTake Requip exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nIf you are taking immediate-release Requip tablets you should not take the extended-release tablets at the same time.\nThe dose and timing of Requip in treating Parkinson\'s disease is different from the dose and timing in treating RLS. Follow the directions on your prescription label. Ask your pharmacist if you have any questions about the kind of ropinirole you receive at the pharmacy.\nRequip can be taken with or without food. Take the medicine at the same time each day.\nDo not crush, chew, or break an extended-release Requip XL tablet. Swallow the tablet whole.\nCall your doctor if you see part of the tablet in your stool. This is a sign that your body may not have absorbed all of the medicine.\nIf you are taking this medicine for RLS, tell your doctor if your symptoms get worse, if they occur in the morning or earlier than usual in the evening, or if you feel restless symptoms in your hands or arms.\nIt may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nDo not stop using Requip suddenly, or you could have unpleasant withdrawal symptoms. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n','Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Dizziness may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.\nDrinking alcohol can increase certain side effects of Requip.\n'),(754,'restasis','1 drop 2 times a day in each eye approximately 12 hours apart\nRestasis can be used concomitantly with artificial tears, allowing a 15 minute interval between products.\n Detailed Restasis dosage information\nWhat happens if I miss a dose?\nApply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.\nWhat happens if I overdose?\nAn overdose of Restasis is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\n','It is not likely that other drugs you take orally or inject will have an effect on cyclosporine used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n','Get emergency medical help if you have signs of an allergic reaction to Restasis: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using this medicine and call your doctor at once if you have:\neye pain; or\neye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection).\nCommon Restasis side effects may include:\nmild burning or stinging in the eyes;\nmild redness or itching;\nblurred vision; or\nfeeling like something is in your eye.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Restasis side effects (more detail)\n','Restasis eye drops contain cyclosporine which is an immunosuppressant. Cyclosporine can increase tear production that has been reduced by inflammation in the eye(s).\nRestasis eye drops are used to treat chronic dry eye that may be caused by inflammation.\nRestasis ophthalmic emulsion may also be used for treating eye disease not listed in this medication guide.\n','Do not touch the Restasis dropper on to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated (dirty), it could cause an infection in the eye(s).\nDo not use this medicine while wearing contact lenses. Contact lenses may be reinserted 15 minutes following the administration of Restasis eye drops, unless otherwise directed by your doctor.\nBefore taking this medicine\nYou should not use Restasis if you are allergic to cyclosporine.\nRestasis is likely safe in pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether Restasis passes into breast milk or if it could harm a nursing baby, although it is likely safe. Tell your doctor if you are breast-feeding a baby.\nThis medicine is not approved for use by anyone younger than 16 years old.\nHow should I use Restasis?\nUse Restasis eye drops exactly as directed by your doctor. Follow all directions on your prescription label. Do not use the eye drops in larger or smaller amounts or for longer than recommended.\nThe usual dose is 1 drop in each eye twice daily. Use Restasis eye drops every 12 hours (approximately).\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\nWash your hands before using the eye drops.\nTo apply the eye drops:\nTurn the bottle upside down a few times to gently mix the medicine. Restasis eye drops should appear white in color.\nTilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.\nClose your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.\nWait at least 15 minutes before using artificial tears, or any other eye drops your doctor has prescribed.\nDo not touch the tip of the eye dropper or place it directly on your eye. A contaminated (dirty) dropper can infect your eye, which could lead to serious vision problems.\nDo not use the drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.\nEach single-use bottle of Restasis is for one use only (in one or both eyes). Throw away the bottle after one use, even if there is still some medicine left in it.\nStore at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.\n','You should not put Restasis in your eyes while wearing contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses. It may be best not to wear contact lenses if you have dry eyes. Talk with your doctor.\n'),(755,'restoril','Usual Adult Dose for Insomnia:\n7.5 to 30 mg orally once a day at bedtime\nComments:\n-In transient insomnia, a 7.5 mg dose may be sufficient to improve sleep latency.\n-In elderly or debilitated patients, therapy should be initiated at 7.5 mg until individual responses are determined.\nUse: Short-term treatment of insomnia (generally 7 to 10 days)\n Detailed Restoril dosage information\nWhat happens if I miss a dose?\nSince Restoril is used when needed, you may not be on a dosing schedule. Take this medicine only when you have time for several hours of sleep. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include extreme drowsiness, confusion, or coma.\n','Taking Restoril with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nOther drugs may interact with temazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Restoril drug interactions (more detail)\n','Temazepam may cause a severe allergic reaction. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; nausea, vomiting; swelling of your face, lips, tongue, or throat.\nRestoril can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. A person caring for you should seek emergency medical attention if you have weak or shallow breathing, if you are hard to wake up, or if you stop breathing.\nCall your doctor at once if you have:\nconfusion, agitation, hallucinations;\ndepressed mood; or\nthoughts of suicide or hurting yourself.\nSome people using temazepam have engaged in activity such as driving, eating, making phone calls, or having sex and later having no memory of the activity. Tell your doctor if this happens to you.\nThe sedative effects of temazepam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines.\nCommon Restoril side effects may include:\nday-time drowsiness or \"hangover\" feeling;\nheadache;\ndizziness, tiredness;\nnausea; or\nfeeling nervous.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Restoril side effects (more detail)\n','Restoril (temazepam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Temazepam affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia).\nRestoril is used to treat insomnia (trouble falling or staying asleep).\nRestoril works by slowing down the central nervous system (brain), causing drowsiness which helps patients fall asleep.\n','Restoril can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing.\nNever take Restoril if you do not have at least 7 to 8 hours to sleep before being active again.\nDo not use Restoril if you are pregnant. Temazepam can cause birth defects or life-threatening withdrawal symptoms in a newborn. Use effective birth control to prevent pregnancy while taking this medicine.\nSome people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking Restoril and talk with your doctor about another treatment for your sleep disorder.\nTemazepam may be habit-forming and should be used only by the person it was prescribed for. This medicine should never be shared with another person, especially someone who has a history of drug abuse or addiction. MISUSE OF TEMAZEPAM CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.\nTemazepam may cause a severe allergic reaction. Stop taking this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Take this medication only when you are getting ready for several hours of sleep. You may fall asleep very quickly after taking the medicine.\nBefore taking this medicine\nYou should not use Restoril if you are allergic to temazepam or similar medicines (such as alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, Xanax, and others).\nDo not use Restoril if you are pregnant. It could harm the unborn baby.\nIf you use temazepam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nlung disease or breathing problems;\ndepression, mental illness, suicidal thoughts;\nalcoholism or drug addiction; or\nliver or kidney disease.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nRestoril is not approved for use by anyone younger than 18 years old.\nHow should I take Restoril?\nTake Restoril exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Never use temazepam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of temazepam.\nNever share Restoril with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.\nTake this medicine only when you are getting ready for several hours of sleep. You may fall asleep very quickly after taking the medicine.\nCall your doctor if your insomnia does not improve after taking Restoril for 7 to 10 nights, or if you have any mood or behavior changes. Insomnia can be a symptom of depression, mental illness, or certain medical conditions.\nDo not stop using Restoril suddenly or you could have unpleasant withdrawal symptoms. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.\n','Do not drink alcohol. Dangerous side effects or death could occur.\nYou may still feel sleepy the morning after taking Restoril. Wait until you are fully awake before you drive, operate machinery, or do anything that requires you to be awake and alert. Your reactions may be impaired.\n'),(756,'retevmo','\nTake Retevmo exactly as your healthcare provider tells you.\nYour healthcare provider may stop treatment or change your dose if you have side effects. Do not change your dose or stop treatment unless your healthcare provider tells you.\nRetevmo is taken by mouth, usually 2 times a day with or without food.\nIf you take a proton-pump inhibitor (PPIs such as dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole sodium, and rabeprazole), take Retevmo with food.\nRetevmo doses should be separated by 12 hours.\nIf you take an antacid that contains aluminum, magnesium, calcium, simethicone, or buffered medicines, take Retevmo 2 hours before or 2 hours after taking the antacid.\nIf you take an H2 blocker (such as famotidine, nizatidine, and cimetidine), take Retevmo 2 hours before or 10 hours after taking the H2 blocker.\nSwallow Retevmo capsules whole. Do not chew or crush the capsules.\nIf you vomit after taking a dose, do not take an extra dose. Take the next dose at your scheduled time.\nDo not take a missed dose unless it is more than 6 hours until your next scheduled dose.\nIf you take too much Retevmo, call your healthcare provider or go to the nearest hospital emergency room right away.\n Detailed Retevmo dosage information\n',NULL,'Retevmo may cause serious side effects, including:\nLiver problems. Liver problems (increased liver enzymes) are common with Retevmo and may sometimes be serious. Your healthcare provider will do blood tests before and during treatment to check for liver problems. Tell your healthcare provider right away if you get any of the following symptoms of liver problems during treatment:\nyellowing of your skin or the white part of your eyes (jaundice)\ndark “tea-colored” urine\nsleepiness\nbleeding or bruising\nloss of appetite\nnausea or vomiting\npain on the upper right side of your stomach area\nYour healthcare provider may temporarily stop treatment, lower your dose, or permanently stop treatment if you develop liver problems with Retevmo.\nHigh blood pressure (hypertension). High blood pressure is common with Retevmo and may sometimes be serious. You should check your blood pressure regularly during treatment. Tell your healthcare provider if you get any of the following symptoms:\nconfusion\nheadaches\nshortness of breath\ndizziness\nchest pain\nHeart rhythm changes (QT prolongation) can occur and may be serious. Retevmo may cause very slow, very fast or irregular heartbeats. Tell your healthcare provider right away if you get any of the following symptoms:\nloss of consciousness\nfainting\ndizziness\na change in the way your heart beats (heart palpitations)\nBleeding problems. Retevmo can cause bleeding which can be serious and may lead to death. Tell your healthcare provider if you have any signs of bleeding during treatment, including:\nvomiting blood or if your vomit looks like coffee-grounds\npink or brown urine\nred or black (looks like tar) stools\ncoughing up blood or blood clots\nunusual bleeding or bruising of your skin\nmenstrual bleeding that is heavier than normal\nunusual vaginal bleeding\nnose bleeds that happen often\ndrowsiness or difficulty being awakened\nconfusion\nheadache\nchange in speech\nAllergic reactions. Retevmo can cause a fever, rash, muscle or joint pain, especially in the first month of treatment. Tell your healthcare provider if you get any of these symptoms. Your healthcare provider may temporarily stop treatment or lower your dose.\nRisk of wound healing problems. Wounds may not heal properly during treatment with Retevmo. Tell your healthcare provider if you plan to have any surgery before or during treatment with Retevmo.\nYou should stop taking Retevmo at least 7 days before planned surgery.\nYour healthcare provider should tell you when you may start taking Retevmo again after surgery.\nThe most common side effects include:\nincreased levels of liver enzymes\nincreased blood sugar levels\ndecrease in white blood cell count\ndecreased protein levels (albumin) in the blood\ndecreased levels of calcium in the blood\ndry mouth\ndiarrhea\nincreased creatinine (kidney function test)\nhigh blood pressure\ntiredness\nswelling of your arms, legs, hands, and feet (peripheral edema)\ndecrease in platelet count\nincreased cholesterol levels\nrash\ndecreased levels of salt (sodium) in the blood\nconstipation\nRetevmo may affect fertility in females and males, which may affect your ability to have children. Talk to your healthcare provider if this is a concern for you.\nThese are not all the possible side effects.\nCall your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Retevmo side effects (more detail)\nHow should I store Retevmo?\nStore Retevmo capsules at room temperature between 68˚F to 77˚F (20˚C to 25˚C).\nKeep all medicines out of the reach of children and pets.\nGeneral information about the safe and effective use of Retevmo.\nMedicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or healthcare provider for more information that is written for health professionals.\nWhat are the ingredients in Retevmo?\nActive ingredient: selpercatinib\nInactive ingredients: microcrystalline cellulose, colloidal silicon dioxide\nCapsule: gelatin, titanium dioxide and edible ink\n','Retevmo is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes in:\nadults with non-small cell lung cancer (NSCLC) that has spread.\nadults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread who require a medicine by mouth or injection (systemic therapy).\nadults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working.\nYour healthcare provider will perform a test to make sure that Retevmo is right for you.\nIt is not known if this medicine is safe and effective in children younger than 12 years of age.\n',NULL,NULL),(757,'revlimid','Usual Adult Dose for Multiple Myeloma:\nIn combination with dexamethasone:\n25 mg orally once a day on Days 1 to 21 of repeated 28-day cycles until disease progression or unacceptable toxicity\nMaintenance therapy following auto-HSCT:\n10 mg once a day continuously (Days 1 to 28 of repeated 28-day cycles) for 3 cycles, then increase to 15 mg once a day if tolerated until disease progression or unacceptable toxicity\nComments:\n-For patients who are not eligible for auto-HSCT, therapy should continue until disease progression or unacceptable toxicity.\n-For patients who are eligible for auto-HSCT, hematopoietic stem cell mobilization should occur within 4 cycles.\n-Following auto-HSCT, initiate maintenance therapy after adequate hematologic recovery (ANC 1000/mcL or more AND/OR platelet count 75,000/mcL or more).\n-Consult the manufacturer product information for dexamethasone dosing recommendations.\nUses:\n-In combination with dexamethasone for multiple myeloma (MM)\n-Maintenance therapy in patients with MM following autologous hematopoietic stem cell transplantation (auto-HSCT)\nUsual Adult Dose for Myelodysplastic Disease:\n10 mg orally once a day; therapy is continued or modified based upon clinical and laboratory findings until disease progression or unacceptable toxicity\nUse: Treatment of transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities\nUsual Adult Dose for Lymphoma:\nFOLLICULAR LYMPHOMA OR MARGINAL ZONE LYMPHOMA:\n20 mg orally once a day on Days 1 through 21 of repeated 28-day cycles for up to 12 cycles in combination with a rituximab-product\nMANTLE CELL LYMPHOMA:\n25 mg orally once a day on Days 1 to 21 of repeated 28-day cycles until disease progression or unacceptable toxicity; treatment is continued, modified, or discontinued based upon clinical and laboratory findings\nUses:\n-For the treatment of patients with mantle cell lymphoma (MCL) whose disease has relapsed or progressed after 2 prior therapies, onw1 of which included bortezomib\nUse: In combination with a rituximab product for the treatment of previously treated follicular lymphoma (FL)\n-In combination with a rituximab product for the treatment of previously treated marginal zone lymphoma (MZL)\n Detailed Revlimid dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor if you also use pembrolizumab (Keytruda).\nIf you use hormonal birth control (pills, implants, injections) to prevent pregnancy: There are certain drugs that can make hormonal birth control less effective in your body. Tell your doctor about all other medicines you use. You may need to replace your hormonal birth control method with another effective form of contraception.\nOther drugs may interact with lenalidomide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Revlimid drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Revlimid: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nCall your doctor at once if you have:\nsigns of a stroke or blood clot - sudden numbness or weakness, severe headache, problems with speech or vision, shortness of breath, swelling or redness in your arm or leg;\nheart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, sweating;\nliver problems - upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nlow blood cell counts - fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, easy bruising, unusual bleeding;\nsigns of a tumor getting worse - swollen glands, low fever, rash, or pain; or\nsigns of tumor cell breakdown - lower back pain, blood in your urine, little or no urinating; numbness or tingly feeling around your mouth; muscle weakness or tightness; feeling short of breath; confusion, fainting.\nCommon Revlimid side effects may include:\nfever, cough, tiredness;\nitching, rash, swelling; or\nnausea, diarrhea, constipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Revlimid side effects (more detail)\n','Revlimid (lenalidomide) affects the immune system. It promotes immune responses to help slow tumor growth.\nRevlimid is used to treat multiple myeloma (bone marrow cancer), either in combination with another medicine or after stem cell transplant.\nRevlimid is also used to treat anemia (a lack of red blood cells) in patients with myelodysplastic syndrome caused by an abnormal chromosome. This disorder is also called deletion 5q MDS, because part of chromosome 5 is missing. In people with this disorder, the bone marrow does not produce enough healthy blood cells.\nRevlimid is also used to treat mantle cell lymphoma (a rare cancer of the lymph nodes), after other medications have been tried without success.\nRevlimid should not be used for chronic lymphocytic leukemia (CLL) unless you are in a controlled medical study. Lenalidomide can increase the risk of death from serious heart problems in people with CLL.\nThis medicine is available only from a certified pharmacy under a special program called Revlimid REMS. Your doctor must be registered in the program in order to prescribe lenalidomide for you. You must be registered in the program and sign documents stating that you understand the dangers of this medication and that you agree to use birth control measures as required by the program.\n','Never use Revlimid if you are pregnant. Even one dose of lenalidomide can cause severe, life-threatening birth defects or death of a baby if the mother or the father is taking this medicine at the time of conception or during pregnancy.\nUse birth control to prevent pregnancy, whether you are a man or a woman. For women: Use two forms of birth control beginning 4 weeks before you start taking Revlimid and ending 4 weeks after you stop taking it. For men: Use a condom to prevent pregnancy during your treatment, and for up to 4 weeks after your treatment ends.\nRevlimid may cause blood clots. Stop using this medicine and call your doctor at once if you have symptoms such as sudden numbness, severe headache, problems with vision or speech, chest pain, shortness of breath, coughing up blood, or swelling in your arm or leg.\nRevlimid can lower blood cells that help your body fight infections and help your blood to clot. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches). You will need frequent blood tests while you are taking Revlimid.\nBefore taking this medicine\nYou should not use Revlimid if you are allergic to lenalidomide.\nRevlimid can cause severe, life-threatening birth defects or death of a baby if the mother or the father is taking this medicine at the time of conception or during pregnancy. Even one dose of lenalidomide can cause major birth defects of the baby\'s arms and legs, bones, ears, eyes, face, and heart. Never use Revlimid if you are pregnant. Tell your doctor right away if your period is late while taking Revlimid.\nFor Women: If you have not had a hysterectomy, you will be required to use two reliable forms of birth control beginning 4 weeks before you start taking Revlimid and ending 4 weeks after you stop taking it. Even women with fertility problems are required to use birth control while taking this medicine. You must also have a negative pregnancy test at 10 to 14 days before treatment and again at 24 hours before. While you are taking Revlimid, you will have a pregnancy test every 2 to 4 weeks.\nThe birth control method you use must be proven highly effective, such as birth control pills, an intrauterine device (IUD), a tubal ligation, or a sexual partner\'s vasectomy. The extra form of birth control you use must be a barrier method such as a latex condom, a diaphragm, or a cervical cap.\nStop using Revlimid and call your doctor at once if you quit using birth control, if your period is late, or if you think you might be pregnant. Not having sexual intercourse (abstinence) is the most effective method of preventing pregnancy.\nFor Men: If a man fathers a baby while using Revlimid, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment, and for up to 4 weeks after your treatment ends. You must agree in writing to always use latex condoms when having sex with a woman who is able to get pregnant, even if you have had a vasectomy. Contact your doctor if you have had unprotected sex, even once, or if you think your female sexual partner may be pregnant.\nTo make sure Revlimid is safe for you, tell your doctor if you have ever had:\nan allergic reaction to thalidomide;\nkidney disease (or if you are on dialysis);\nliver disease;\na blood clots or stroke;\nhigh blood pressure, high cholesterol or triglycerides;\na thyroid disorder; or\nlactose intolerance.\nUsing Revlimid may increase your risk of developing other types of cancer, such as leukemia or lymphoma. Talk with your doctor about your specific risk.\nYou should not breast-feed while using Revlimid.\nHow should I take Revlimid?\nTake Revlimid exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Never share this medicine with another person, even if they have the same disorder you have.\nTake the medicine at the same time each day. You may take Revlimid with or without food.\nTake each dose with a full glass of water. Swallow the capsule whole, without breaking it open.\nLenalidomide can increase your risk of bleeding or infection. Your blood will need to be tested often.\nThe medicine from an open capsule can be dangerous if it gets on your skin. If this occurs, wash your skin with soap and water. Ask your doctor or pharmacist how to safely handle and dispose of a broken capsule.\nStore Revlimid at room temperature away from moisture and heat.\n','You must not donate blood or sperm while you are using Revlimid, and for at least 4 weeks after your last dose. Avoid exposing another person to your blood or semen through casual or sexual contact.\nThis medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient\'s body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.\n'),(758,'rexulti','Usual Adult Dose for Schizophrenia:\nInitial dose: 1 mg orally once a day on Days 1 through 4\nTitration regimen: Based on clinical response and tolerability, titrate to 2 mg once a day on Days 5 to 7, then to 4 mg once a day on Day 8.\nMaintenance dose: 2 to 4 mg orally once a day\nMaximum dose: 4 mg/day\nUse: Treatment of schizophrenia\nUsual Adult Dose for Depression:\nInitial dose: 0.5 mg to 1 mg orally once a day\nTitration regimen: Based on clinical response and tolerability, dose increases should be done at weekly intervals; titrate to 1 mg once a day, then up 2 mg once a day.\nMaintenance dose: 2 mg orally once a day\nMaximum dose: 3 mg/day\nComment: Healthcare providers should periodically reassess the need for maintenance treatment.\nUse: Adjunctive treatment of major depressive disorder (MDD)\n Detailed Rexulti dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may interact with brexpiprazole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Rexulti drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rexulti: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nHigh doses or long-term use of Rexulti can cause a serious movement disorder that may not be reversible. The longer you use this medicine, the more likely you are to develop this disorder, especially if you are a diabetic or an older adult.\nCall your doctor at once if you have:\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\ntrouble swallowing;\nfeelings of warmth, intolerance to heat;\na seizure (convulsions);\na light-headed feeling, like you might pass out;\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor;\nlow white blood cell counts - fever, mouth sores, skin sores, sore throat, cough, trouble breathing;\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors; or\nsigns of a blood clot - sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg.\nYou may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.\nCommon Rexulti side effects may include:\nweight gain; or\nfeeling restless or being unable to sit still.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rexulti side effects (more detail)\n','Rexulti (brexpiprazole) is an antipsychotic medication. It works by changing the actions of chemicals in the brain.\nRexulti is used to treat the symptoms of schizophrenia.\nRexulti is also used together with other medications to treat major depressive disorder in adults.\n','Rexulti is not approved for use in older adults with dementia-related psychosis.\nSome young people have thoughts about suicide when first taking this medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nRexulti is not approved for use by anyone younger than 18 years old.\nBefore taking this medicine\nRexulti may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.\nYou should not use Rexulti if you are allergic to brexpiprazole.\nTell your doctor if you have ever had:\ndiabetes or high blood sugar;\nliver disease;\nkidney disease;\nhigh cholesterol or triglycerides (a type of fat in the blood);\nheart problems, high or low blood pressure;\nheart attack or stroke;\na seizure; or\nlow white blood cell (WBC) counts.\nSome young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nTaking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking Rexulti without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of brexpiprazole on the baby.\nIt may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.\nRexulti is not approved for use by anyone younger than 18 years old.\nHow should I take Rexulti?\nTake Rexulti exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYou may take Rexulti with or without food.\nDrink plenty of fluids, especially in hot weather and during exercise. You may get dehydrated easily while taking Rexulti.\nYou should not stop using this medicine suddenly. Stopping suddenly may make your condition worse.\nRexulti may cause high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis while you are taking this medicine.\nStore at room temperature away from moisture and heat.\n','Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy.\nAvoid becoming overheated or dehydrated in hot weather. Brexpiprazole can make it harder for your body to control its own temperature. It is easier to become dangerously overheated and dehydrated while you are taking this medicine.\n'),(759,'reyvow','Usual Adult Dose for Migraine:\nInitial dose: 50 mg, 100 mg, or 200 mg orally once\nMaximum dose: 1 dose per day\nComments:\n-This drug should not be taken unless the patient can wait 8 hours or more before driving or operating machinery.\n-No more than 1 dose should be taken in 24 hours; a second dose has not been shown to be effective for the same migraine attack.\n-The safety of treating an average of more than 4 migraine attacks in a 30-day period has not been established.\n-This drug is not indicated for the prevention of migraine attacks.\nUse: For the acute treatment of migraine with or without aura.\n Detailed Reyvow dosage information\nWhat happens if I miss a dose?\nSince Reyvow is used once when needed, it does not have a daily dosing schedule. Call your doctor if your migraine symptoms do not improve after using this medicine.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Using Reyvow with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nMany drugs may interact with lasmiditan. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Reyvow drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Reyvow: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nCommon Reyvow side effects may include:\ndizziness, drowsiness;\nfeeling tired; or\nnumbness or tingling.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Reyvow side effects (more detail)\n','Reyvow (lasmiditan) is a serotonin (5-HT) 1F receptor agonist.\nReyvow is used in adults to treat migraine headaches with or without aura.\nReyvow will only treat and will not prevent migraine headache.\n','Reyvow is a federally controlled substance (CV) because it contains lasmiditan that can be a target for people who abuse prescription medicines or street drugs.\nKeep this medicine in a safe place to protect it from theft. Never give your Reyvow to anyone else, because it may harm them. Selling or giving away Reyvow is against the law. Tell your healthcare provider if you have ever abused or been dependent on alcohol, prescription medicines or street drugs.\nDo not take more than one dose in a 24-hour period.\nFor at least 8 hours after taking Reyvow, do not drive and avoid other hazardous activity.\nBefore taking this medicine\nTo make sure Reyvow is safe for you, tell your doctor if you have:\nan allergy to lasmiditan;\nliver disease;\nslow heartbeats;\nhigh blood pressure; or\ndrug addiction.\nBe sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with lasmiditan and cause a serious condition called serotonin syndrome.\nTell your doctor if you are pregnant or plan to become pregnant. It is not known whether lasmiditan will harm an unborn baby. However, having migraine headaches during pregnancy may cause complications such as eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating migraines may outweigh any risks to the baby.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nReyvow is not approved for use by anyone younger than 18 years old.\nHow should I take Reyvow?\nTake Reyvow exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nReyvow may be habit-forming. Misuse can cause addiction, overdose, or death. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.\nTake Reyvow soon as you notice headache symptoms.\nDo not take more than one dose in a 24-hour period.\nYou may take this medicine with or without food.\nNever use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.\nCall your doctor if your headache does not go away completely, or if you have more than 4 headaches in one month (30 days).\nStore at room temperature away from moisture and heat.\nKeep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.\n','After taking Reyvow, do not drive for at least 8 hours, and avoid other hazardous activity. Your reactions could be impaired, and you may not realize the extent of that impairment.\nDrinking alcohol with this medicine can cause side effects.\n'),(760,'rifampin','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nRifampin oral is taken by mouth. Rifampin injection is given as an infusion into a vein.\nTake rifampin oral on an empty stomach, at least 1 hour before or 2 hours after a meal. Take each dose with a full glass of water.\nA healthcare provider will give you rifampin injection. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when rifampin is injected.\nRifampin may cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (a yellow, orange, red, or brown color). This side effect is usually not harmful. However, soft contact lenses may be permanently stained if you wear them while using rifampin.\nDark colored urine can be a sign of liver problems. Call your doctor if you have reddish-brown urine together with upper stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).\nUse this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may increase your risk of further infection that is resistant to antibiotics. Rifampin will not treat a viral infection such as the flu or a common cold.\nYou should not stop using rifampin without your doctor\'s advice. Stopping the medicine suddenly and later starting again may cause kidney problems. Rifampin is usually given until lab tests show that the infection has cleared.\nWhile using rifampin, you may need frequent blood tests.\nThis medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use rifampin.\nStore at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.\n Detailed Rifampin dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose can cause worsening symptoms such as nausea, vomiting, stomach pain, itching, headache, lack of energy leading to loss of consciousness, and dark or discolored skin, saliva, tears, urine, or stools.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nRifampin can harm your liver, especially if you also use certain medicines for infections, tuberculosis, depression, birth control, hormone replacement, high cholesterol, heart problems, high blood pressure, seizures, pain, or arthritis (including Tylenol, Advil, Motrin, or Aleve).\nMany drugs can affect rifampin, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.\n Rifampin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, rash, feeling light-headed, wheezing, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nSeek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.\nCall your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody;\nchest pain, cough, shortness of breath;\na light-headed feeling, like you might pass out;\neasy bruising, unusual bleeding (nosebleeds, bleeding gums);\npounding heartbeats or fluttering in your chest;\nflu symptoms--fever, chills, body aches, headache, weakness, nausea, vomiting; or\nliver problems--upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nred discoloration of your teeth, sweat, urine, saliva, and tears;\nheartburn, gas, upset stomach, loss of appetite;\nnausea, vomiting, diarrhea;\nfever;\nheadache, dizziness, drowsiness, tiredness;\nmuscle weakness, pain in your arms or legs;\nproblems with balance or muscle movement;\nnumbness; or\nconfusion, changes in behavior, trouble concentrating.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rifampin side effects (more detail)\n','Rifampin is an antibiotic that is used to treat or prevent tuberculosis (TB).\nRifampin may also be used to reduce certain bacteria in your nose and throat that could cause meningitis or other infections. Rifampin prevents you from spreading these bacteria to other people, but  rifampin will not treat an active meningitis infection.\nRifampin may also be used for purposes not listed in this medication guide.\n','Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.\nBefore taking this medicine\nYou should not use  rifampin if you are allergic to rifampin or similar medicines such as rifabutin, rifapentine, rifamycin, or rifaximin.\nMany drugs can interact and cause dangerous effects. Some drugs should not be used together with rifampin. Your doctor may change your treatment plan if you also use: atazanavir, darunavir, fosamprenavir, praziquantel, ritonavir, saquinavir, or tipranavir.\nTell your doctor if you have ever had:\ndiabetes;\nliver disease;\nbleeding problems; or\nporphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).\nIt is not known whether this medicine will harm an unborn baby. However, using rifampin during the last few weeks of pregnancy may cause bleeding in the mother or the newborn baby. Tell your doctor if you are pregnant.\nRifampin can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using rifampin, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.\nYou should not breastfeed while using this medicine.\n','Avoid drinking alcohol. It may increase your risk of liver damage.\nAvoid wearing contact lenses. Rifampin may discolor your tears, which could permanently stain soft contact lenses.\n'),(761,'rifaximin','Usual Adult Dose for Traveler\'s Diarrhea:\n200 mg orally 3 times a day for 3 daysComments:-Should not use in patients with diarrhea complicated by fever and/or blood in the stool or diarrhea caused by pathogens other than Escherichia coliUse: For the treatment of travelers\' diarrhea due to noninvasive strains of E coli\nUsual Adult Dose for Hepatic Encephalopathy:\n550 mg orally twice a dayComments:-In trials, lactulose was used concomitantly in 91% of patients; differences in treatment effect of patients not using concomitant lactulose could not be assessed.Use: For reduction in risk of overt hepatic encephalopathy recurrence\nUsual Adult Dose for Irritable Bowel Syndrome:\n550 mg orally 3 times a day for 14 daysComments:-If symptoms recur, patients can be retreated up to 2 times with the same dose regimen.Use: For the treatment of irritable bowel syndrome with diarrhea\nUsual Pediatric Dose for Traveler\'s Diarrhea:\n12 years or older: 200 mg orally 3 times a day for 3 daysComments:-Should not use in patients with diarrhea complicated by fever and/or blood in the stool or diarrhea caused by pathogens other than E coliUse: For the treatment of travelers\' diarrhea due to noninvasive strains of E coli\n Detailed Rifaximin dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Tell your doctor about all your other medicines, especially:\ncyclosporine;\nketoconazole;\nwarfarin (Coumadin, Jantoven);\nan antibiotic--clarithromycin, erythromycin;\nantiviral medicine--ritonavir, saquinavir; or\nheart or blood pressure medicine--amiodarone, quinidine, verapamil.\nThis list is not complete. Other drugs may affect rifaximin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rifaximin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);\nfever; or\nfluid build-up around the stomach--rapid weight gain, stomach pain and bloating, trouble breathing while lying down.\nCommon side effects may include:\nswelling in your hands or feet;\nnausea;\nheadache, dizziness;\ntiredness; or\nabnormal liver function tests.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rifaximin side effects (more detail)\n','Rifaximin is used to treat travelers\' diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old. Most people get this infection by eating food or drinking fluids that have been contaminated with the E. coli bacteria.\nRifaximin is also used to treat irritable bowel syndrome (IBS) in adults whose main symptom is diarrhea.\nRifaximin is also used to lower the risk of a decline in brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.\nRifaximin may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not take  rifaximin if you are allergic to rifaximin, rifabutin, rifampin, or rifapentine.\nTell your doctor if you have ever had:\nliver disease;\ndiarrhea with a fever; or\nwatery or bloody diarrhea.\nTell your doctor if you are pregnant or breastfeeding.\nRifaximin should not be given to a child younger than 12 years old.\nHow should I take rifaximin?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nYou may take rifaximin with or without food.\nFor travelers\' diarrhea, rifaximin is usually taken for only 3 days. For IBS, rifaximin is usually taken for 2 weeks at a time. Follow your doctor\'s dosing instructions very carefully.\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Rifaximin will not treat a viral infection such as the flu or a common cold.\nDo not share this medicine with another person, even if they have the same symptoms you have.\nCall your doctor if your symptoms do not improve after 24 to 48 hours, or if they get worse while using rifaximin.\nRifaximin does not treat all bacterial forms of travelers\' diarrhea.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.\n'),(762,'rinvoq','Usual Adult Dose for Rheumatoid Arthritis:\n15 mg orally once a day\nComments:\n-This drug may be used as monotherapy or in combination with methotrexate or other nonbiologic DMARDs.\n-This drug is not recommended in patients with an absolute lymphocyte count (ALC) less than 500 cells/mm3, absolute neutrophil count (ANC) less than 1000 cells/mm3, or hemoglobin level less than 8 g/dL.\nUse: Treatment of patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response or intolerance to methotrexate.\n Detailed Rinvoq dosage information\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nTell your doctor about all your other medicines, especially:\nphenytoin;\nan antibiotic - clarithromycin, rifampin;\nantifungal medicine - fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole;\ndrugs that weaken the immune system - azathioprine, cyclosporine, and others;\nNSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or\nsteroid medicine - dexamethasone, prednisone, and others.\nThis list is not complete. Other drugs may interact with Rinvoq, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rinvoq drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rinvoq: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nYou may get infections more easily, even serious or fatal infections. Call your doctor right away if you have signs of infection such as:\nfever, chills, sweating;\nskin sores;\ntiredness, muscle pain;\nincreased urination, pain or burning when you urinate;\nstomach pain, diarrhea, weight loss; or\ncough, shortness of breath, coughing up pink or red mucus.\nFurther doses may be delayed until your infection clears up.\nAlso call your doctor at once if you have:\nshingles - burning pain, numbness, tingling, itching, skin rash or blisters;\nsigns of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;\nsigns of a blood clot in your leg - swelling, warmth, or redness in the leg;\nsigns of perforation (a hole or tear) in your stomach or intestines - fever, ongoing stomach pain, change in bowel habits; or\nsigns of tuberculosis: fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired.\nCommon Rinvoq side effects may include:\nfever;\ncough;\nnausea; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rinvoq side effects (more detail)\n','Rinvoq (upadacitinib) is a prescription medicine that is a Janus kinase (JAK) inhibitor.\nRinvoq is used to treat adults with moderate to severe rheumatoid arthritis in patients that could not tolerate methotrexate or if treatment with methotrexate did not work well.\nIt is not known if Rinvoq is safe and effective in children under 18 years of age.\n','Rinvoq affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, cough, skin sores, diarrhea, weight loss, or burning when you urinate.\nYou should not start taking Rinvoq if you have any kind of infection. Your doctor may perform tests to make sure you do not have tuberculosis or other infections.\nBefore taking this medicine\nYou should not use Rinvoq if you have any kind of infection.\nTo make sure Rinvoq is safe for you, tell your doctor if you have ever had:\na chronic infection;\nliver or kidney disease;\nhepatitis B or C;\na stomach or intestinal problem such as diverticulitis or an ulcer;\na perforation (a hole or tear) in your esophagus, stomach, or intestines;\na blood clot;\ncancer;\nlow red or white blood cell counts;\na weak immune system (caused by disease or by using certain medicine);\nherpes zoster (also called shingles);\nhigh cholesterol;\nlung disease;\ndiabetes; or\nif you are scheduled to receive any vaccine.\nTell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.\nUsing Rinvoq may increase your risk of developing certain cancers, such as lymphoma or skin cancer. Ask your doctor about this risk.\nYou may need to have a negative pregnancy test before starting this treatment.\nUpadacitinib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 4 weeks after your last dose.\nYou should not breastfeed while using Rinvoq and for at least 6 days after your last dose.\nRinvoq is not approved for use by anyone younger than 18 years old.\nHow should I take Rinvoq?\nTake Rinvoq exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nBefore you start treatment with Rinvoq, your doctor may perform tests to make sure you do not have tuberculosis or other infections.\nTake this medicine with a full glass of water.\nTake the medicine at the same time each day, with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nRinvoq affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.\nStore Rinvoq in the original container at room temperature, away from moisture and heat.\n','Do not receive a \"live\" vaccine while using Rinvoq. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\n'),(763,'risdiplam','Usual Adult Dose for Spinal Muscular Atrophy:\n5 mg orally once a dayComments:-See Other Comments/Administration Advice for important information on dose preparation and administration.Use: For the treatment of spinal muscular atrophy.\nUsual Pediatric Dose for Spinal Muscular Atrophy:\n2 months to less than 2 years: 0.2 mg/kg orally once a day2 years and older weight less than 20 kg: 0.25 mg/kg orally once a day2 years and older weight 20 kg or more: 5 mg orally once a dayComments:-See Other Comments/Administration Advice for important information on dose preparation and administration.Use: For the treatment of spinal muscular atrophy in patients 2 months of age and older.\n Detailed Risdiplam dosage information\n','Other drugs may affect risdiplam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Risdiplam drug interactions (more detail)\nDoes Risdiplam interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\npain or burning when you urinate; or\nsigns of a lung infection--fever, cough with mucus, chest pain, feeling short of breath.\nCommon side effects may include:\nfever, lung infection;\nnausea, vomiting;\ndiarrhea, constipation;\nrash; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Risdiplam side effects (more detail)\n','Risdiplam is used to treat a genetic condition called spinal muscular atrophy (weakness and wasting of the muscles needed for movement of the body).\nRisdiplam is for use in adults and children at least 2 months old.\nRisdiplam may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nRisdiplam is not approved for use in a child younger than 2 months old.\nTell your doctor if you have ever had liver problems.\nYou may need to have a negative pregnancy test before starting this treatment. Tell your doctor if you plan to become pregnant.\nRisdiplam may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using  risdiplam and for at least 1 month after your last dose. Tell your doctor right away if you become pregnant.\nRisdiplam may affect fertility (ability to have children), in men. Talk to your doctor if you have concerns about this risk.\nHow should I take risdiplam?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nA healthcare provider will teach you how to properly prepare the daily dose. Read and carefully follow any Instructions for Use provided with your medicine.\nRisdiplam is supplied as a liquid that must be mixed at the pharmacy. Do not use this medicine in powder form. If you receive the medicine as a powder, ask your pharmacist to mix the medicine for you.\nMeasure risdiplam carefully. Use only one of the dosing syringes provided (choose the syringe size for your correct dose). Do not use a kitchen spoon or any other medicine dose-measuring device.\nPrepare a dose only when you are ready to give it. After placing risdiplam into the oral syringe, you must give the medicine within 5 minutes. If not given within 5 minutes, throw out the liquid and prepare a new dose.\nAlways take this medicine after a meal, at the same time each day.\nIf the child using risdiplam is breastfed, give the medicine after feeding. Do not mix risdiplam with infant formula or milk.\nTo make sure you swallow the entire dose, drink a glass water after taking the medicine.\nIf the entire dose is not swallowed or if you vomit shortly after taking risdiplam, do not take another dose. Wait until your next scheduled dose time to take the medicine again.\nIf you are giving this medicine through a nasogastric or gastrostomy tube, your doctor should first check the tube. Follow all directions about how to give risdiplam through the tube, and flush the tube with water after each dose.\nAvoid getting this medicine in your eyes or on your skin. If this happens, wash your skin with soap and water or rinse your eyes with water.\nThe oral syringe is reusable. Wash the syringe after each use and allow it to air dry. If your syringe is lost or damaged, call your pharmacist for a new one.\nStore risdiplam in the original bottle in an upright position in the refrigerator. Protect from light and do not freeze. Keep the bottle tightly closed when not in use. Throw away any unused liquid if it has been longer than 64 days since it was mixed at the pharmacy.\nRisdiplam doses are based on weight in children. Your child\'s dose needs will change as the child grows and gains weight.\nDo not stop taking risdiplam or change your dose without your doctor\'s advice.\nWhat happens if I miss a dose?\nUse the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Go back to the regular schedule the following day. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(764,'risedronate','Risedronate tablets come in different strengths (number of milligrams per pill) that are taken on different schedules. You may need to take a tablet once per day, once per week, once per month, or for 2 days in a row once per month.\nYour dosing schedule will depend on why you are taking risedronate and in what tablet strength. If you change strengths, you may also need to change your schedule.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Risedronate is often given for only 3 to 5 years.\nTake the Actonel tablet first thing in the morning with a full glass (6 to 8 ounces) of water, at least 30 minutes before you eat or drink anything or take any other medicine.\nTake the Atelvia tablet just after breakfast, with at least 4 ounces of water.\nUse only plain water when taking a risedronate tablet. Do not use coffee, tea, soda, juice, or mineral water.\nDo not crush, chew, or suck on a risedronate tablet. Swallow it whole.\nFor at least 30 minutes after taking risedronate:\nDo not lie down or recline.\nDo not take any other medicine including vitamins, calcium, iron, antacids, or laxatives.\nTake this medicine at the same time each day or on the same day each week or each month (depending on your dosing schedule).\nPay special attention to your dental hygiene while taking risedronate. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using risedronate.\nRisedronate is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture and heat. Keep unused effervescent tablets in the foil blister pack.\n Detailed Risedronate dosage information\nWhat happens if I miss a dose?\nOnce-daily dosing: If you forget to take risedronate first thing in the morning, do not take it later in the day. Wait until the following morning and skip the missed dose. Do not take two (2) doses in one day.\nOnce-per-week or once-per-month dosing: If you forget to take risedronate on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly or monthly schedule on your chosen dose day. Do not take 2 doses in one day.\nCall your doctor for instructions if you miss more than 2 doses in a month.\nWhat happens if I overdose?\nDrink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.\n','Tell your doctor about all your other medicines, especially:\naspirin;\ncalcium or iron supplements;\nantacids, laxatives; or\nNSAIDs (nonsteroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\nThis list is not complete. Other drugs may affect risedronate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Risedronate drug interactions (more detail)\nDoes Risedronate interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop using risedronate and call your doctor at once if you have:\nchest pain, new or worsening heartburn;\ndifficulty or pain when swallowing;\npain or burning under the ribs or in the back;\nsevere heartburn, burning pain in your upper stomach, or coughing up blood;\nnew or unusual pain in your thigh or hip;\njaw pain, numbness, or swelling;\nsevere joint, bone, or muscle pain; or\nlow calcium levels--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).\nCommon side effects may include:\nheartburn, diarrhea, indigestion;\nstomach pain;\nback pain, joint pain, muscle pain; or\nflu-like symptoms.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Risedronate side effects (more detail)\n','Risedronate is used to treat osteoporosis caused by menopause, or steroid use.  risedronate is for use when you have a high risk of bone fracture due to osteoporosis.\nRisedronate is also used to treat Paget\'s disease of bone.\nRisedronate may also be used for purposes not listed in this medication guide.\n','You should not take risedronate if you have problems with your esophagus, or low levels of calcium in your blood.\nDo not take risedronate if you cannot sit upright or stand for at least 30 minutes after taking the medicine.\nRisedronate can cause serious problems in the stomach or esophagus. Stop using risedronate and call your doctor at once if you have chest pain, new or worsening heartburn, or pain when swallowing.\nAlso call your doctor if you have muscle spasms, numbness or tingling (in hands and feet or around the mouth), new or unusual hip pain, or severe pain in your joints, bones, or muscles.\nBefore taking this medicine\nYou should not take risedronate if you are allergic to it, or if you have:\nlow levels of calcium in your blood (hypocalcemia); or\nproblems with the muscles in your esophagus (the tube that connects your mouth and stomach).\nDo not take risedronate if you cannot sit upright or stand for at least 30 minutes. Risedronate can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking  risedronate.\nTell your doctor if you have ever had:\ntrouble swallowing;\nproblems with your stomach or digestion;\nhypocalcemia;\na dental problem (you may need a dental exam before you begin taking risedronate);\nkidney disease; or\nany condition that makes it hard for your body to absorb nutrients from food (malabsorption).\nThis medicine may cause jaw bone problems (osteonecrosis). The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Ask your doctor about your own risk.\nTalk with your doctor about the risks and benefits of using this medication.\nIt is not known whether this medicine will harm an unborn baby. Stop taking risedronate and tell your doctor right away if you become pregnant, or think you may be pregnant.\nYou should not breastfeed while using risedronate.\nRisedronate should not be given to a child younger than 18 years old.\n','Do not take two different brands or strengths of risedronate at the same time.\nAvoid taking any other medicines for at least 30 minutes after taking risedronate. This includes vitamins, calcium, iron, antacids, or laxatives. Some medicines can make it harder for your body to absorb risedronate.\nAvoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.\nAvoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.\n'),(765,'risperdal','Take Risperdal exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nRisperdal can be taken with or without food.\nRemove the Risperdal M-Tab orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nDo not mix the Risperdal liquid with cola or tea.\nIt may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nStore at room temperature away from moisture, heat, and light. Do not liquid medicine to freeze.\n Detailed Risperdal dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck.\n','Taking Risperdal with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your other medicines, especially:\nblood pressure medication;\ncarbamazepine;\nclozapine;\nfluoxetine (Prozac) or paroxetine (Paxil); or\nlevodopa.\nThis list is not complete. Other drugs may interact with risperidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Risperdal drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Risperdal: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\nbreast swelling or tenderness (in men or women), nipple discharge, impotence, lack of interest in sex, missed menstrual periods;\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;\nlow white blood cells - sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;\nlow levels of platelets in your blood - easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or\npenis erection that is painful or lasts 4 hours or longer.\nCommon Risperdal side effects may include:\nheadache;\ndizziness, drowsiness, feeling tired;\ntremors, twitching or uncontrollable muscle movements;\nagitation, anxiety, restless feeling;\ndepressed mood;\ndry mouth, upset stomach, diarrhea, constipation;\nweight gain; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Risperdal side effects (more detail)\n','Risperdal (risperidone) is an antipsychotic medicine that works by changing the effects of chemicals in the brain.\nRisperdal is used to treat schizophrenia in adults and children who are at least 13 years old.\nRisperdal is also used to treat symptoms of bipolar disorder (manic depression) in adults and children who are at least 10 years old.\nRisperdal is also used to treat symptoms of irritability in autistic children who are 5 to 16 years old.\n','Risperdal is not approved for use in older adults with dementia-related psychosis.\nDo not give Risperdal to a child without a doctor\'s advice.\nWhile you are taking this medicine, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication.\nRisperidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of risperidone.\nStop using Risperdal and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting.\nBefore taking this medicine\nYou should not use Risperdal if you are allergic to risperidone.\nRisperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nheart disease, high blood pressure, heart rhythm problems, stroke or heart attack;\ndiabetes (or risk factors such as obesity or family history of diabetes);\nlow white blood cell (WBC) counts;\nliver or kidney disease;\nseizures;\nbreast cancer;\nlow bone mineral density;\ntrouble swallowing;\nParkinson\'s disease; or\nif you are dehydrated.\nThe Risperdal M-Tab orally disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).\nTaking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking , do not stop taking it without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of risperidone on the baby.\nRisperidone may temporarily affect fertility (ability to have children) in women.\nRisperidone can pass into breast milk and may cause side effects in the baby. If you breast-feed while using Risperdal, tell your doctor if the baby has symptoms such as drowsiness, tremors, or involuntary muscle movements.\nDo not give this medicine to a child without a doctor\'s advice.\n','Avoid driving or hazardous activity until you know how risperidone will affect you. Your reactions could be impaired.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries.\nAvoid drinking alcohol. Dangerous side effects could occur.\nWhile you are taking risperidone, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise.\n'),(766,'risperidone','Take risperidone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nRisperidone can be taken with or without food.\nRemove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nDo not mix the liquid medicine with cola or tea.\nIt may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nStore at room temperature away from moisture, heat, and light. Do not liquid medicine to freeze.\n Detailed Risperidone dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck.\n','Taking risperidone with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.\nTell your doctor about all your other medicines, especially:\nblood pressure medication;\ncarbamazepine;\nclozapine;\nfluoxetine (Prozac) or paroxetine (Paxil); or\nlevodopa.\nThis list is not complete. Other drugs may interact with risperidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Risperidone drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to risperidone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\nbreast swelling or tenderness (in men or women), nipple discharge, impotence, lack of interest in sex, missed menstrual periods;\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;\nlow white blood cells - sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;\nlow levels of platelets in your blood - easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or\npenis erection that is painful or lasts 4 hours or longer.\nCommon risperidone side effects may include:\nheadache;\ndizziness, drowsiness, feeling tired;\ntremors, twitching or uncontrollable muscle movements;\nagitation, anxiety, restless feeling;\ndepressed mood;\ndry mouth, upset stomach, diarrhea, constipation;\nweight gain; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Risperidone side effects (more detail)\n','Risperidone is an antipsychotic medicine that works by changing the effects of chemicals in the brain.\nRisperidone is used to treat schizophrenia in adults and children who are at least 13 years old.\nRisperidone is also used to treat symptoms of bipolar disorder (manic depression) in adults and children who are at least 10 years old.\nRisperidone is also used to treat symptoms of irritability in autistic children who are 5 to 16 years old.\n','Risperidone is not approved for use in older adults with dementia-related psychosis.\nDo not give risperidone to a child without a doctor\'s advice.\nWhile you are taking this medicine, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication.\nRisperidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of this medicine.\nStop using this medicine and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting.\nBefore taking this medicine\nYou should not use risperidone if you are allergic to it.\nRisperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nheart disease, high blood pressure, heart rhythm problems, stroke or heart attack;\ndiabetes (or risk factors such as obesity or family history of diabetes);\nlow white blood cell (WBC) counts;\nliver or kidney disease;\nseizures;\nbreast cancer;\nlow bone mineral density;\ntrouble swallowing;\nParkinson\'s disease; or\nif you are dehydrated.\nThe risperidone orally disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).\nTaking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking risperidone, do not stop taking it without your doctor\'s advice.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of risperidone on the baby.\nThis medicine may temporarily affect fertility (ability to have children) in women.\nRisperidone can pass into breast milk and may cause side effects in the baby. If you breast-feed while using this medicine, tell your doctor if the baby has symptoms such as drowsiness, tremors, or involuntary muscle movements.\nDo not give this medicine to a child without a doctor\'s advice.\n','Avoid driving or hazardous activity until you know how risperidone will affect you. Your reactions could be impaired.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries.\nAvoid drinking alcohol. Dangerous side effects could occur.\nWhile you are taking risperidone, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise.\n'),(767,'ritalin','Take Ritalin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take Ritalin in larger or smaller amounts or for longer than recommended.\nYour dose needs may change if you switch to a different brand, strength, or form of methylphenidate. Avoid medication errors by using only the form and strength your doctor prescribes.\nRitalin may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\nTo prevent sleep problems, take this medicine in the morning.\nRitalin tablets and Ritalin SR tablets should be taken at least 30 to 45 minutes before a meal. Extended-release Ritalin LA capsules can be taken with or without food. Follow the directions on your medicine label.\nDo not crush, chew, or break a sustained-release tablet. Swallow the tablet whole. Breaking the tablet may cause too much of the drug to be released at one time.\nTo make swallowing easier, you may open the Ritalin LA capsule and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow right away without chewing. Do not save the mixture for later use.\nWhile using Ritalin, your doctor will need to check your progress at regular visits. Tell any doctor who treats you that you are using this medicine.\nIf you need surgery, tell the surgeon ahead of time that you are using Ritalin. You may need to stop using the medicine for a short time.\nStore at room temperature away from moisture and heat.\nKeep track of your medicine. Methylphenidate is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.\n Detailed Ritalin dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is later than 6:00 p.m. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of methylphenidate could be fatal.\n','Ask your doctor before using a stomach acid medicine (including Alka-Seltzer or sodium bicarbonate). Some of these medicines can change the way your body absorbs methylphenidate, and may increase side effects.\nMany drugs can interact with methylphenidate. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Ritalin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Ritalin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsigns of heart problems - chest pain, trouble breathing, feeling like you might pass out;\nsigns of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;\nsigns of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes;\na seizure (convulsions);\nmuscle twitches (tics);\nchanges in your vision; or\npenis erection that is painful or lasts 4 hours or longer (rare).\nMethylphenidate can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.\nCommon Ritalin side effects may include:\nexcessive sweating;\nmood changes, feeling nervous or irritable, sleep problems (insomnia);\nfast heart rate, pounding heartbeats or fluttering in your chest, increased blood pressure;\nloss of appetite, weight loss;\ndry mouth, nausea, stomach pain; or\nheadache.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ritalin side effects (more detail)\n','Ritalin (methylphenidate) is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.\nRitalin is used to treat attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), and narcolepsy.\nRitalin may also be used for purposes not listed in this medication guide.\n','You should not use Ritalin if you have glaucoma, tics or Tourette\'s syndrome, or severe anxiety, tension, or agitation.\nMethylphenidate may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.\nStimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.\nDo not use Ritalin if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.\nMethylphenidate may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.\nYou may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.\nCall your doctor right away if you have: signs of heart problems - chest pain, feeling light-headed or short of breath; signs of psychosis - paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems - unexplained wounds on your fingers or toes.\nBefore taking this medicine\nDo not use Ritalin if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nYou may not be able to use Ritalin if you are allergic to methylphenidate, or if you have:\nglaucoma;\na personal or family history of tics (muscle twitches) or Tourette\'s syndrome; or\nsevere anxiety, tension, or agitation (stimulant medicine can make these symptoms worse).\nStimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have:\nheart problems or a congenital heart defect;\nhigh blood pressure; or\na family history of heart disease or sudden death.\nTo make sure Ritalin is safe for you, tell your doctor if you or anyone in your family has ever had:\ndepression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions;\nmotor tics (muscle twitches) or Tourette\'s syndrome;\nblood circulation problems in the hands or feet;\nseizures or epilepsy;\nproblems with the esophagus, stomach, or intestines;\nan abnormal brain wave test (EEG); or\na history of drug or alcohol addiction.\nIt is not known whether Ritalin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of methylphenidate on the baby.\nIt is not known whether methylphenidate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nRitalin is not approved for use by anyone younger than 6 years old.\n','Methylphenidate may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\n'),(768,'rituxan','Rituxan is given as an infusion into a vein. A healthcare provider will give you this injection.\nYour doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Rituxan.\nRituxan is not given daily. Your schedule will depend on the condition being treated. Follow your doctor\'s dosing instructions very carefully.\nBefore each injection, you may be given other medications to prevent certain side effects of rituximab.\nYou will need frequent medical tests.\nIf you\'ve ever had hepatitis B, using Rituxan can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.\nIf you need surgery, tell the surgeon ahead of time that you are using this medicine.\n Detailed Rituxan dosage information\nWhat happens if I miss a dose?\nCall your doctor if you miss an appointment for your Rituxan injection.\nWhat happens if I overdose?\nSince this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.\n','Tell your doctor about all your other medicines, especially:\nmedicines to treat conditions such as rheumatoid arthritis, Crohn\'s disease, ulcerative colitis, or psoriasis - adalimumab, certolizumab, etanercept, golimumab, infliximab, leflunomide, methotrexate, sulfasalazine, tocilizumab, tofacitinib, and others; or\nchemotherapy drugs, especially cisplatin\nThis list is not complete. Other drugs may interact with rituximab, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rituxan drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rituxan: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nSome side effects may occur during the injection (or within 24 hours afterward). Tell your caregiver right away if you feel itchy, dizzy, weak, light-headed, short of breath, or if you have a rash or hives, chest pain, wheezing, sudden cough, or pounding heartbeats or fluttering in your chest.\nRituximab may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have any of the following symptoms (which may start gradually and get worse quickly):\nconfusion, memory problems, or other changes in your mental state;\nweakness on one side of your body;\nvision changes; or\nproblems with speech or walking.\nRituxan can lead to other serious side effects including infections, heart attacks or other heart problems, kidney failure, and intestinal blockage and/or damage. Talk to your doctor about your risk.\nCall your doctor at once if you have any of these other side effects, even if they occur several months after you receive Rituxan, or after your treatment ends.\npainful skin or mouth sores, or a severe skin rash with blistering, peeling, or pus;\nredness, warmth, or swelling of the skin;\nsevere stomach pain, vomiting, constipation, bloody or tarry stools;\nirregular heartbeats, chest pain or pressure, pain spreading to your jaw or shoulder;\ntiredness or jaundice (yellowing of the skin or eyes);\nsigns of infection - fever, chills, cold or flu symptoms, cough, sore throat, mouth sores, headache, earache, pain or burning when you urinate; or\nsigns of tumor cell breakdown - confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.\nCommon Rituxan side effects may include:\nlow white and red blood cells (fever, chills, body aches, pale skin, unusual tiredness, infections);\nnausea, diarrhea;\nswelling in your hands or feet;\nheadache, weakness;\npainful urination;\nmuscle spasms;\ndepressed mood; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rituxan side effects (more detail)\n','Rituxan (rituximab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. It is also used to treat other non-cancer conditions.\nRituxan is an intravenous (IV) infusion given by a healthcare professional. It is a prescription medicine used alone or in combination with other medicines to treat the following conditions:\nnon-Hodgkin\'s lymphoma or chronic lymphocytic leukemia in adults;\nrheumatoid arthritis in adults;\ngranulomatosis with polyangiitis and microscopic polyangiitis (rare disorders that cause inflammation of blood vessels and other tissues in the body) in adults and children 2 years of age and older; or\npemphigus vulgaris (a severe autoimmune reaction that causes blisters and breakdown of the skin and mucous membranes) in adults.\n','Rituxan may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.\nTell your doctor if you have ever had hepatitis B. Rituxan can cause this condition to come back or get worse.\nSevere skin problems can also occur during treatment with Rituxan. Call your doctor if you have painful skin or mouth sores, or a severe skin rash with blistering, peeling, or pus.\nSome side effects may occur during the infusion or within 24 hours afterward. Tell your caregiver right away if you feel itchy, dizzy, weak, light-headed, short of breath, or if you have chest pain, wheezing, sudden cough, or pounding heartbeats or fluttering in your chest.\nDo not receive a \"live\" vaccine while using Rituxan, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\nBefore taking this medicine\nRituxan may cause a serious brain infection that can lead to disability or death. This infection may be more likely if have used an immunosuppressant drug in the past, or if you have received Rituxan with a stem cell transplant.\nTo make sure this medicine is safe for you, tell your doctor if you have ever had:\nliver disease or hepatitis (or if you are a carrier of hepatitis B);\nkidney disease;\nlung disease or a breathing disorder;\na weak immune system (caused by disease or by using certain medicines);\nan infection, including herpes, shingles, cytomegalovirus, chickenpox, parvovirus, West Nile virus, or hepatitis B or C;\nheart disease, angina (chest pain), or heart rhythm disorder; or\nif you have used rituximab in the past, or you have had a severe allergic reaction to rituximab.\nYou should be up-to-date on any needed immunizations before starting treatment with Rituxan. Tell your doctor if you (or a child receiving Rituxan) have received any vaccines within the past 4 weeks.\nDo not use Rituxan if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 12 months after your last dose.\nIt is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 6 months after your last dose.\nIf you are a woman of childbearing age, you should use birth control while taking Rituxan and for at least 12 months after your last dose.\n','Do not receive a \"live\" vaccine while using rituximab, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\n'),(769,'rituximab','Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using rituximab.\nRituximab is given as an infusion into a vein. A healthcare provider will give you this injection.\nRituximab is not given daily. Your schedule will depend on the condition being treated. Follow your doctor\'s dosing instructions very carefully.\nBefore each injection, you may be given other medications to prevent certain side effects of rituximab.\nYou will need frequent medical tests.\nIf you\'ve ever had hepatitis B, using rituximab can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.\nIf you need surgery, tell the surgeon ahead of time that you are using rituximab.\n Detailed Rituximab dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nCall your doctor if you miss an appointment for your rituximab injection.\nWhat happens if I overdose?\nSince this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.\n','Tell your doctor about all your other medicines, especially:\nmedicines to treat conditions such as rheumatoid arthritis, Crohn\'s disease, ulcerative colitis, or psoriasis--adalimumab, certolizumab, etanercept, golimumab, infliximab, leflunomide, methotrexate, sulfasalazine, tocilizumab, tofacitinib, and others.\nThis list is not complete. Other drugs may affect rituximab, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rituximab drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nSome side effects may occur during the injection (or within 24 hours afterward). Tell your caregiver right away if you feel itchy, dizzy, weak, light-headed, short of breath, or if you have chest pain, wheezing, sudden cough, or pounding heartbeats or fluttering in your chest.\nRituximab may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have any of the following symptoms (which may start gradually and get worse quickly):\nconfusion, memory problems, or other changes in your mental state;\nweakness on one side of your body;\nvision changes; or\nproblems with speech or walking.\nCall your doctor at once if you have any of these other side effects, even if they occur several months after you receive rituximab, or after your treatment ends.\npainful skin or mouth sores, or a severe skin rash with blistering, peeling, or pus;\nredness, warmth, or swelling of the skin;\nsevere stomach pain, vomiting, constipation, bloody or tarry stools;\nirregular heartbeats, chest pain or pressure, pain spreading to your jaw or shoulder;\ntiredness or jaundice (yellowing of the skin or eyes);\nsigns of infection--fever, chills, cold or flu symptoms, cough, sore throat, mouth sores, headache, earache, pain or burning when you urinate; or\nsigns of tumor cell breakdown--confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.\nCommon side effects may include:\nlow white and red blood cells (fever, chills, body aches, pale skin, unusual tiredness, infections);\nnausea, diarrhea;\nswelling in your hands or feet;\nheadache, weakness;\npainful urination;\nmuscle spasms;\ndepressed mood; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rituximab side effects (more detail)\n','Rituximab is used alone or in combination with other medicines to treat the following conditions in adults:\nnon-Hodgkin\'s lymphoma or chronic lymphocytic leukemia;\nrheumatoid arthritis; or\npemphigus vulgaris--a severe autoimmune reaction that causes blisters and breakdown of the skin and mucous membranes.\nRituximab is also used in adults and children at least 2 years old with certain disorders that cause inflammation of blood vessels and other tissues in the body.\nRituximab may also be used for purposes not listed in this medication guide.\n','Rituximab may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.\nTell your doctor if you have ever had hepatitis B. Rituximab can cause this condition to come back or get worse.\nSevere skin problems can also occur during treatment with rituximab. Call your doctor if you have painful skin or mouth sores, or a severe skin rash with blistering, peeling, or pus.\nSome side effects may occur during the injection or within 24 hours afterward. Tell your caregiver right away if you feel itchy, dizzy, weak, light-headed, short of breath, or if you have chest pain, wheezing, sudden cough, or pounding heartbeats or fluttering in your chest.\nBefore taking this medicine\nRituximab may cause a serious brain infection that can lead to disability or death. This infection may be more likely if have used an immunosuppressant drug in the past, or if you have received rituximab with a stem cell transplant.\nTell your doctor if you have ever had:\nliver disease or hepatitis (or if you are a carrier of hepatitis B);\nan infection, including herpes, shingles, cytomegalovirus, chickenpox, parvovirus, West Nile virus, or hepatitis B or C;\nkidney disease;\nlung disease or a breathing disorder;\na weak immune system (caused by disease or by using certain medicines);\nheart disease, angina (chest pain), or heart rhythm disorder; or\nif you have used rituximab in the past, or you have had a severe allergic reaction to rituximab.\nYou should be up-to-date on any needed immunizations before starting treatment with rituximab. Tell your doctor if you (or a child receiving rituximab) have received any vaccines within the past 4 weeks.\nDo not use rituximab if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using  rituximab and for at least 12 months after your last dose.\nDo not breastfeed while using this medicine, and for at least 6 months after your last dose.\n','Do not receive a \"live\" vaccine while using rituximab. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.\n'),(770,'rivaroxaban','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nThe number of times you take rivaroxaban each day will depend on the reason you are using this medication.\nFor some conditions, rivaroxaban should be taken with food. Whether you take the medicine with or without food may also depend on the tablet strength you take. Follow your doctor\'s dosing instructions very carefully.\nTell your doctor if you have trouble swallowing a rivaroxaban tablet.\nTell any doctor who treats you that you are using rivaroxaban. If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using this medication. If you need anesthesia for a medical procedure or surgery, you may need to stop using rivaroxaban for a short time.\nDo not change your dose or stop taking this medication without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.\nStore at room temperature away from moisture and heat.\n Detailed Rivaroxaban dosage information\nWhat happens if I miss a dose?\nIf you take rivaroxaban 1 time each day: Take the medicine as soon as you remember, and then go back to your regular schedule. Do not take two doses in the same day.\nIf you take the 2.5-milligram tablet 2 times each day: Skip the missed dose and take your next dose at the regular time.\nIf you take the 15-milligram tablet 2 times each day: Take the missed dose on the same day you remember it. You may take 2 doses at the same time to make up a missed dose.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose may cause excessive bleeding.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may affect rivaroxaban, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Rivaroxaban drug interactions (more detail)\nDoes Rivaroxaban interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nAlso seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.\nRivaroxaban can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as:\neasy bruising or bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding);\npain, swelling, new drainage, or excessive bleeding from a wound or where a needle was injected in your skin;\nany bleeding that will not stop;\nheadaches, dizziness, weakness, feeling like you might pass out;\nurine that looks red, pink, or brown; or\nbloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nBleeding is the most common side effect of rivaroxaban.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rivaroxaban side effects (more detail)\n','Rivaroxaban is used to treat or prevent blood clots (venous thromboembolism, or VTE). Blood clots can occur in the legs (deep vein thrombosis, DVT) or the lungs (pulmonary embolism, PE).\nBlood clots can develop when you are very ill and cannot move around as much as normal, such as during or after a stay in the hospital. Blood clots may also develop after knee or hip replacement surgery.\nRivaroxaban is sometimes used to lower your risk of a blood clot coming back after you have received treatment for blood clots for at least 6 months.\nRivaroxaban is also used in people with atrial fibrillation (a heart rhythm disorder) to lower the risk of stroke caused by a blood clot.\nRivaroxaban is also given together with aspirin to lower the risk of stroke, heart attack, or other serious heart problems in people with coronary artery disease (decreased blood flow to the heart) or peripheral artery disease (decreased blood flow to the legs).\nRivaroxaban may also be used for purposes not listed in this medication guide.\n','Do not stop taking rivaroxaban without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.\nCall your doctor at once if you have signs of bleeding such as: headaches, feeling very weak or dizzy, bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.\nMany other drugs can increase your risk of bleeding when used with rivaroxaban. Tell your doctor about all medicines you have recently used.\nRivaroxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Tell any doctor who treats you that you are taking rivaroxaban.\nBefore taking this medicine\nYou should not use rivaroxaban if you are allergic to it, or if you have active or uncontrolled bleeding.\nRivaroxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:\nyou have a genetic spinal defect;\nyou have a spinal catheter in place;\nyou have a history of spinal surgery or repeated spinal taps;\nyou have recently had a spinal tap or epidural anesthesia;\nyou are taking an NSAID--Advil, Aleve, Motrin, and others; or\nyou are using other medicines to treat or prevent blood clots.\nRivaroxaban may cause you to bleed more easily, especially if you have:\na bleeding disorder that is inherited or caused by disease;\nhemorrhagic stroke;\nuncontrolled high blood pressure;\nstomach or intestinal bleeding or ulcer; or\nif you take certain medicines such as aspirin, enoxaparin, heparin, warfarin (Coumadin, Jantoven), clopidogrel (Plavix), or certain antidepressants.\nTell your doctor if you have ever had:\nantiphospholipid syndrome (also called Hughes syndrome or \"sticky blood syndrome\"), an immune system disorder that increases the risk of blood clots;\nan artificial heart valve; or\nliver or kidney disease.\nTaking rivaroxaban during pregnancy may cause bleeding in the mother or the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breastfeed a baby while you are using  rivaroxaban. Ask your doctor about any risks.\n','Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.\n'),(771,'rivastigmine','Usual Adult Dose for Alzheimer\'s Disease:\nMILD TO MODERATE ALZHEIMER\'S DISEASE:ORAL:-Initial dose: 1.5 mg orally twice a day -Maintenance dose: After a minimum of 2 weeks of treatment, if the initial dosage is well tolerated, it can be increased to 3 mg twice a day; subsequent increases to 4.5 mg and 6 mg twice a day should be attempted only after a minimum of 2 weeks at the previous dosage TRANSDERMAL PATCH: -Initial Dose: 4.6 mg/24 hour patch applied to the skin once daily-Maintenance Dose: After a minimum of 4 weeks of treatment at the initial dose, and if well tolerated, the dose can be increased to 9.5 mg/24 hours for as long as this dose is beneficial; the dose can then be increased to 13.3 mg/24 hours-Maximum Dose: 13.3 mg/24 hour patch applied to skin daily; higher doses confer no appreciable additional benefit, and are associated with significant increase in the incidence of adverse eventsSEVERE ALZHEIMER\'S DISEASE:TRANSDERMAL PATCH: -Recommended dose: 13.3 mg/24 hours transdermal patch applied to skin once daily; replace with a new patch every 24 hoursUse: For the treatment of mild, moderate, or severe dementia of the Alzheimer\'s type (AD)\nUsual Adult Dose for Parkinson\'s Disease:\nMILD TO MODERATE PARKINSON\'S DISEASE DEMENTIA:ORAL:Initial dose: 1.5 mg orally twice a day with morning and evening mealsMaintenance dose: Subsequently, the dose can be increased to 3 mg orally twice a day and further to 4.5 mg twice a day and 6 mg twice a day (based on tolerability) with a minimum of 4 weeks at each dose TRANSDERMAL PATCH:Initial dose: 4.6 mg/24 hours applied to the skin once a dayMaintenance dose: After a minimum of four weeks of treatment and if well tolerated, the dose of the patch can be increased to 9.5 mg/24 hours for as long as this dose is beneficial.  The dose can then be increased to 13.3 mg/24 hours.Maximum dose: 13.3 mg/24 hours.  Higher doses confer no appreciable additional benefit, and are associated with significant increase in the incidence of adverse events.Use: For the treatment of mild to moderate dementia associated with Parkinson\'s disease\n Detailed Rivastigmine dosage information\n','Tell your doctor about all your other medicines, especially:\nmedicine to treat depression, anxiety, mood disorders, or mental illness;\ncold or allergy medicine (Benadryl and others);\nbeta blocker heart or blood pressure medication;\nmedicine to treat Parkinson\'s disease;\nmedicine to treat nausea/vomiting, stomach problems, motion sickness, or irritable bowel syndrome;\nmedicine to treat overactive bladder;\nbronchodilator asthma medication; or\nan NSAID (nonsteroidal anti-inflammatory drug such as aspirin, ibuprofen, naproxen, Advil, Motrin, Aleve, and others.\nThis list is not complete and many other drugs may affect rivastigmine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rivastigmine drug interactions (more detail)\nDoes Rivastigmine interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere or ongoing vomiting or diarrhea, loss of appetite, weight loss;\nbloody or tarry stools, cough with bloody mucus or vomit that looks like coffee grounds;\na light-headed feeling, like you might pass out;\ntremors (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck;\nseizure (convulsions);\npainful or difficult urination;\nsevere skin redness, itching, or irritation; or\ndehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.\nCommon side effects may include:\nupset stomach, nausea, vomiting;\nloss of appetite; or\nweakness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rivastigmine side effects (more detail)\n','Rivastigmine is used to treat mild to moderate dementia caused by Alzheimer\'s or Parkinson\'s disease.\nRivastigmine is not a cure for Alzheimer\'s or Parkinson\'s disease.\nRivastigmine may also be used for purposes not listed in this medication guide.\n','You should not take oral rivastigmine if you have ever had severe redness, itching, or skin irritation caused by wearing a rivastigmine transdermal skin patch.\nBefore taking this medicine\nYou should not take  rivastigmine if you are allergic to rivastigmine or similar medicines, such as felbamate, meprobamate, or carisoprodol.\nYou should not take oral rivastigmine if you have ever had severe redness, itching, or skin irritation caused by wearing a rivastigmine transdermal skin patch.\nTell your doctor if you have ever had:\nan ulcer or stomach bleeding;\na seizure;\nheart problems;\nliver or kidney disease;\nurination problems; or\nasthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder.\nTell your doctor if you are pregnant or plan to become pregnant.\nIt may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.\nHow should I take rivastigmine?\nDo not wear a rivastigmine transdermal skin patch at the same time you are taking rivastigmine capsules or oral liquid.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nTake rivastigmine with food.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nYou may swallow the liquid medicine directly from the syringe or mix the medicine with a small glass of water, fruit juice, or soda. Stir and drink this mixture within 4 hours after mixing. Add a little more water to the glass, swirl gently and drink right away.\nAfter using the syringe, wipe the outside of it with a clean tissue and put the syringe back into its protective case. Close the medicine bottle using the child-resistant closure.\nCall your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking rivastigmine.\nRivastigmine doses are based on weight. Your dose needs may change if you gain or lose weight.\nIf you need surgery, tell your surgeon you currently use this medicine.\nIf you stop taking rivastigmine for any reason, do not restart the medicine without talking to your doctor first. You may need to start with a lower dose.\nStore in an upright position at room temperature, away from moisture and heat. Do not allow the liquid medicine to freeze.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nIf you miss several doses in a row, call your doctor before taking any more of  rivastigmine.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe nausea, vomiting, salivation, sweating, slow heartbeats, weak or shallow breathing, fainting, or seizure (convulsions).\n','Avoid driving or hazardous activity until you know how  rivastigmine will affect you. Your reactions could be impaired.\n'),(772,'rizatriptan','Usual Adult Dose for Migraine:\nUse only after a clear diagnosis of migraine has been establishedInitial dose: 5 mg or 10 mg orally, once-Provided there has been a response to first dose, a second dose may be administered at least 2 hours later if migraine returnsMaximum dose: 30 mg in a 24-hour period Comments:-The 10 mg dose may provide greater effect, however there may be a greater risk of adverse reactions.-This drug should not be used to treat basilar or hemiplegic migraines because these patients are at a greater risk of stroke.-The safety of treating an average of 4 or more migraine attacks in a 30-day period has not been established; the effectiveness of a second dose or subsequent doses has not been established in placebo-controlled trials.  Use: For the acute treatment of migraine with or without aura.\nUsual Pediatric Dose for Migraine:\nUse only after a clear diagnosis of migraine has been established6 years or older and weight less than 40 kg: -Initial dose: 5 mg orally once6 years or older and weight 40 kg or greater: -Initial dose: 10 mg orally onceMaximum: 1 dose in any 24-hour period Comments:-This drug should not be used to treat basilar or hemiplegic migraines because these patients are at a greater risk of stroke.-The safety of treating an average of 4 or more migraine attacks in a 30-day period has not been established; the safety and effectiveness of more than 1 dose within 24 hours has not been established.  Use: For the acute treatment of migraine with or without aura in patients 6 years or older.\n Detailed Rizatriptan dosage information\n','Tell your doctor about all your other medicines, especially:\npropranolol;\nan antidepressant; or\nmedicine to treat a mood disorder.\nThis list is not complete. Other drugs may affect rizatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\nTell your doctor about all your other medicines, especially any type of antidepressant.\nOther drugs may affect rizatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Rizatriptan drug interactions (more detail)\nDoes Rizatriptan interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using rizatriptan and call your doctor at once if you have:\nsudden and severe stomach pain and bloody diarrhea;\ncold feeling or numbness in your feet and hands;\nsevere headache, blurred vision, pounding in your neck or ears;\nheart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;\nhigh levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea; or\nsigns of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.\nCommon side effects may include:\ndizziness, drowsiness, feeling tired; or\npain or a feeling of pressure in your throat or chest.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rizatriptan side effects (more detail)\n','Rizatriptan is a headache medicine that narrows the blood vessels around the brain. Rizatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.\nRizatriptan is used to treat migraine headaches. Rizatriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.\nRizatriptan should not be used to treat a common tension headache, or a headache that causes loss of movement on one side of your body. Use  rizatriptan only if your condition has been confirmed by a doctor as migraine headaches.\nRizatriptan may also be used for purposes not listed in this medication guide.\n','You should not use this medicine if you have uncontrolled high blood pressure, heart problems, a history of heart attack or stroke, or circulation problems that cause a lack of blood supply within the body.\nDo not take rizatriptan within 24 hours before or after using another migraine headache medicine.\nDo not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.\nBefore taking this medicine\nYou should not use rizatriptan if you are allergic to it, or if you have:\nheart problems, or a stroke (including \"mini-stroke\");\ncoronary artery disease, angina (chest pain), blood circulation problems, lack of blood supply to the heart;\ncirculation problems affecting your legs, arms, stomach, intestines, or kidneys;\nuncontrolled high blood pressure;\nsevere liver disease; or\na headache that seems different from your usual migraine headaches.\nDo not use rizatriptan if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.\nTell your doctor if you have ever had:\nliver or kidney disease;\nheart problems, chest pain;\nshortness of breath; or\nrisk factors for coronary artery disease (such as high blood pressure, high cholesterol, diabetes, menopause, smoking, a family history of coronary artery disease, being overweight, or being older than 40 and a man).\nBe sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with rizatriptan and cause a serious condition called serotonin syndrome.\nRizatriptan disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).\nTell your doctor if you are pregnant or breastfeeding.\nRizatriptan is not approved for use by anyone younger than 6 years old.\nHow should I use rizatriptan?\nTake rizatriptan as soon as you notice headache symptoms. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nYou may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nTake the regular tablet whole with a full glass of water.\nRemove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.\nAfter taking a tablet (for adults): If your headache does not completely go away, or goes away and comes back, take a second tablet 2 hours after the first. If your symptoms have not improved, contact your doctor before taking any more tablets.\nAfter taking a tablet (for children ages 6 to 17): If your headache does not completely go away, or goes away and comes back, contact your doctor before taking any more tablets.\nNever use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.\nCall your doctor if your symptoms do not improve, or if you have more than 4 headaches in one month (30 days).\nRizatriptan can raise blood pressure to dangerous levels. Your blood pressure may need to be checked often while you are using  rizatriptan. If you use rizatriptan long-term, your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nSince rizatriptan is used when needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using this medicine.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Do not take rizatriptan within 24 hours before or after using another migraine headache medicine, including:\nalmotriptan, eletriptan, frovatriptan, naratriptan, sumatriptan, zolmitriptan; or\nergot medicine--dihydroergotamine, ergotamine, ergonovine, methylergonovine.\nAvoid driving or hazardous activity until you know how  rizatriptan will affect you. Your reactions could be impaired.\n'),(773,'robitussin','Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.\nDo not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.\nDrink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.\nTake Robitussin with food if it upsets your stomach.\nMeasure the liquid form of Robitussin with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.\nDo not crush, chew, break, or open a controlled-release, delayed-release, or extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.\nStore at room temperature away from moisture, heat, and direct sunlight.\n Detailed Robitussin Chest Congestion dosage information\nWhat happens if I miss a dose?\nSince cough medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','There may be other drugs that can interact with Robitussin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.\n','Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nLess serious side effects may include:\ndizziness or headache,\na rash, or\nnausea, vomiting, or stomach upset.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Robitussin Chest Congestion side effects (more detail)\n','Robitussin (guaifenesin) is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.\nRobitussin is used to reduce chest congestion caused by the common cold, infections, or allergies.\nIt may also be used for purposes not listed in this medication guide.\n','You should not use this medicine if you are allergic to Robitussin (guaifenesin).\nUse this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.\nDo not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.\nDrink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.\nThis medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\nBefore taking this medicine\nYou should not use this medicine if you are allergic to Robitussin (guaifenesin).\nFDA pregnancy category C. It is not known whether Robitussin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.\nIt is not known whether Robitussin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.\n Robitussin Chest Congestion pregnancy and breastfeeding warnings (more detail)\n','This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.\n'),(774,'rocephin','Take Rocephin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nRocephin is injected into a muscle or as an infusion into a vein (IV).\nA healthcare provider will give you this injection when Rocephin is used to prevent infection from surgery.\nYou may be shown how to use the injection at home to treat an infection. Rocephin is sometimes given for up to 14 days.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don\'t understand all instructions.\nPrepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.\nAn IV injection must be given slowly, and the infusion can take at least 30 minutes to complete.\nUse this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Rocephin will not treat a viral infection such as the flu or a common cold.\nDo not mix Rocephin in the same injection with other antibiotics, or with any diluent that contains calcium, including a TPN (total parenteral nutrition) solution.\nIf you use other injectable medications, be sure to flush your intravenous catheter between injections of each medication.\nRocephin can affect the results of certain medical tests. Tell any doctor who treats you that you are using Rocephin.\nRocephin is usually mixed with a diluent to prepare it for use. Mixed medicine must be used within a certain number of hours or days. This will depend on the diluent and how you store the mixture (at room temperature, in a refrigerator, or frozen). Carefully follow the mixing and storage instructions provided with your medicine. Ask your pharmacist if you have questions.\nIf your medicine was provided in a frozen form, thaw it in a refrigerator or at room temperature. Do not warm in a microwave or boiling water. Use the medicine as soon as possible after thawing it. Do not refreeze.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n Detailed Rocephin dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Tell your doctor about all your other medicines, especially:\nfluconazole;\nvancomycin; or\nother injected (IV) antibiotics.\nThis list is not complete. Other drugs may interact with ceftriaxone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rocephin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rocephin (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nCall your doctor at once if you have:\nsevere stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);\nnew signs of infection (fever, chills, sweating);\nnausea, vomiting, pain in your upper stomach that spreads to your back;\npale or yellowed skin, dark colored urine;\nnew or worsening breathing problems (wheezing, feeling short of breath);\na blood cell disorder - headache, chest pain, dizziness, weakness, severe tingling or numbness; or\nkidney or bladder problems - pain in your side or lower back spreading to your groin, blood in your urine, painful or difficult urination, little or no urine.\nCommon Rocephin side effects may include:\nsymptoms of a blood cell disorder;\ndiarrhea;\nvaginal itching or discharge;\nwarmth, tight feeling, or a hard lump where the injection was given;\nrash; or\nabnormal liver function tests.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rocephin side effects (more detail)\n','Rocephin (ceftriaxone) is a cephalosporin (SEF a low spor in) antibiotic. . It works by fighting bacteria in your body.\nRocephin is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as E. coli, pneumonia, or meningitis.\nRocephin is also used to prevent infection in people having certain types of surgery.\n','You should not use Rocephin if you have ever had a severe allergic reaction to any type of cephalosporin antibiotic (Omnicef, Keflex, and others).\nDo not use Rocephin in a child without a doctor\'s advice. Rocephin should never be used in a premature baby, or in any newborn baby who has jaundice (yellowing of the skin or eyes).\nBefore taking this medicine\nDo not use Rocephin in a child without a doctor\'s advice, and never give more than the child\'s prescribed dose. Rocephin injection can be dangerous when given to a newborn baby with any intravenous medicines that contain calcium, including total parental nutrition (TPN).\nYou should not use this medicine if you have ever had a severe allergic reaction to ceftriaxone or to certain antibiotics, such as:\ncefaclor, cefdinir, cefixime, cefpodoxime, cefprozil, cephalexin, Keflex, Omnicef, and others;\navibactam, relebactam, sulbactam, tazobactam, vaborbactam, and others; or\namoxicillin (Amoxil, Augmentin, Moxatag), ampicillin, dicloxacillin, oxacillin, penicillin, and others.\nTo make sure Rocephin is safe for you, tell your doctor if you have ever had:\nliver or kidney disease;\ngallbladder disease;\ndiabetes; or\nbleeding problems.\nTell your doctor if you are pregnant or breastfeeding.\n','Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.\n'),(775,'ropinirole','Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.\nIf you are taking immediate-release ropinirole (Requip) you should not take extended-release ropinirole (Requip XL) at the same time.\nThe dose and timing of ropinirole in treating Parkinson\'s disease is different from the dose and timing in treating RLS. Follow the directions on your prescription label. Ask your pharmacist if you have any questions about the kind of ropinirole you receive at the pharmacy.\nRopinirole can be taken with or without food. Take the medicine at the same time each day.\nDo not crush, chew, or break an extended-release tablet (Requip XL). Swallow it whole.\nCall your doctor if you see part of the ropinirole tablet in your stool. This is a sign that your body may not have absorbed all of the medicine.\nIf you are taking this medicine for RLS, tell your doctor if your symptoms get worse, if they occur in the morning or earlier than usual in the evening, or if you feel restless symptoms in your hands or arms.\nIt may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nDo not stop using ropinirole suddenly, or you could have unpleasant withdrawal symptoms. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.\n Detailed Ropinirole dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Taking ropinirole with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication, muscle relaxer, or medicine for anxiety, depression, or seizures.\nOther drugs may interact with ropinirole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Ropinirole drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nSome people taking ropinirole have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.\nYou may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.\nCall your doctor at once if you have:\nextreme drowsiness, falling asleep suddenly (even after feeling alert);\nworsening or no improvement in your symptoms;\na light-headed feeling, like you might pass out;\nunusual changes in mood or behavior;\ntremors, twitching uncontrollable muscle movements; or\nhallucinations (seeing or hearing things that are not real).\nSide effects such as confusion or hallucinations may be more likely in older adults.\nCommon side effects may include:\ndrowsiness, dizziness, weakness;\nheadache, confusion, hallucinations;\nincreased blood pressure (severe headache, pounding in your neck or ears, nosebleed, irregular heartbeats);\nnausea, vomiting, upset stomach, constipation;\nflu symptoms (fever, chills, body aches);\nsudden muscle movements;\nincreased sweating; or\nswelling in your legs or feet.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ropinirole side effects (more detail)\n','Ropinirole has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson\'s disease.\nRopinirole is used to treat symptoms of Parkinson\'s disease (stiffness, tremors, muscle spasms, and poor muscle control). Ropinirole is also used to treat restless legs syndrome (RLS).\nOnly immediate-release ropinirole (Requip) is approved to treat either Parkinson symptoms or RLS. Extended-release ropinirole (Requip XL) is approved only to treat Parkinson symptoms.\nParkinson\'s and RLS are two separate disorders. Having one of these conditions will not cause you to have the other condition.\nRopinirole may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use ropinirole if you are allergic to it.\nTo make sure ropinirole is safe for you, tell your doctor if you have:\nhigh or low blood pressure;\nkidney disease (or if you are on dialysis);\nheart disease, heart rhythm problems;\na sleep disorder such as narcolepsy, or other conditions that may cause daytime sleepiness; or\nif you smoke.\nPeople with Parkinson\'s disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.\nIt is not known whether  ropinirole will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether ropinirole passes into breast milk or if it could affect the nursing baby. Ropinirole may slow breast milk production. Tell your doctor if you are breast-feeding.\nRopinirole is not approved for use by anyone younger than 18 years old.\n','Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Dizziness may impair your thinking or reactions. Avoid driving or operating machinery until you know how  ropinirole will affect you.\nDrinking alcohol can increase certain side effects of ropinirole.\n'),(776,'rosuvastatin','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nRosuvastatin is usually taken once a day, with or without food. Take the medicine at the same time each day.\nWhile using rosuvastatin, you may need frequent blood tests.\nKeep using  rosuvastatin as directed, even if you feel well. High cholesterol usually has no symptoms. You may need to take rosuvastatin on a long-term basis.\nYou may need to stop using rosuvastatin for a short time if you have:\nuncontrolled seizures;\nan electrolyte imbalance (such as high or low potassium levels in your blood);\nseverely low blood pressure;\na severe infection or illness;\ndehydration; or\nsurgery or a medical emergency.\nYou should not stop using rosuvastatin unless your doctor tells you to.\nRosuvastatin is only part of a treatment program that may also include diet, exercise, and weight control. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture, heat, and light.\n Detailed Rosuvastatin dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','When you start or stop taking rosuvastatin, your doctor may need to adjust the doses of any other medicines you take on a regular basis. Using certain medicines together with rosuvastatin can increase your risk of serious muscle problems. It is very important to tell your doctor about all medicines you use, and those you start or stop using during your treatment with rosuvastatin, especially:\ncolchicine;\ncyclosporine;\nantifungal medicine--fluconazole, itraconazole, ketoconazole;\nantiviral medicine to treat HIV or hepatitis C--atazanavir, fosamprenavir, ledipasvir, lopinavir, ritonavir, simeprevir, sofosbuvir, tipranavir, Epclusa, Mavyret, Viekira, Vosevi, and others;\na blood thinner--warfarin, Coumadin, Jantoven;\ncancer medicine--darolutamide, regorafenib;\nmedicines that contain niacin or nicotinic acid--vitamin B3, Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others; or\nother cholesterol medications--fenofibrate, gemfibrozil.\nThis list is not complete. Other drugs may affect rosuvastatin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Rosuvastatin drug interactions (more detail)\nDoes Rosuvastatin interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nunexplained muscle pain, tenderness, or weakness;\nmuscle weakness in your hips, shoulders, neck, and back;\ntrouble lifting your arms, trouble climbing or standing;\nconfusion, memory problems; or\nliver problems--upper stomach pain, tiredness, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).\nCommon side effects may include:\nheadache;\nweakness;\nmuscle aches; or\nnausea, stomach pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rosuvastatin side effects (more detail)\n','Rosuvastatin is used together with diet to lower blood levels of \"bad\" cholesterol (low-density lipoprotein, or LDL), to increase levels of \"good\" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).\nRosuvastatin is also used to treat hereditary types of high cholesterol (hypercholesterolemia): The heterozygous type (inherited from one parent) or the homozygous type (inherited from both parents).\nFor the heterozygous type, rosuvastatin can be used in children who are at least 8 years old. For the homozygous type, rosuvastatin can be used in children as young as 7 years old.\nThe Ezallor brand of rosuvastatin is for use only in adults.\nCrestor is also used in adults to slow the progression of atherosclerosis (a build-up of plaque in blood vessels that can block blood flow).\nCrestor is also used to lower the risk of stroke, heart attack, and other complications in men 50 years and older or women 60 years and older who have coronary heart disease or other risk factors.\nRosuvastatin may also be used for purposes not listed in this medication guide.\n','Do not use rosuvastatin if you are pregnant. It could harm the unborn baby.\nYou should not take rosuvastatin if you have liver disease, or if you breastfeeding a baby.\nBefore taking this medicine\nYou should not take rosuvastatin if you are allergic to it, or if you have:\nliver disease; or\nif you are pregnant or breast-feeding.\nDo not take rosuvastatin if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are taking rosuvastatin. Stop taking rosuvastatin and tell your doctor right away if you become pregnant.\nDo not breastfeed while you are taking rosuvastatin.\nTell your doctor if you have ever had:\nliver problems;\nkidney disease;\na thyroid disorder;\na habit of drinking more than 2 alcoholic beverages per day;\nif you are of Asian descent; or\nif you are 65 or older.\nRosuvastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).\nPeople of Asian descent may absorb rosuvastatin at a higher rate than other people. Make sure your doctor knows if you are Asian. You may need a lower than normal starting dose.\n','Avoid eating foods high in fat or cholesterol, or rosuvastatin will not be as effective.\nAvoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.\nSome antacids can make it harder for your body to absorb rosuvastatin. Avoid taking an antacid that contains aluminum or magnesium within 2 hours after taking rosuvastatin.\n'),(777,'roxicodone','Take Roxicodone exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Never use Roxicodone in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more oxycodone .\nNever share opioid medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away opioid medicine is against the law.\nTake Roxicodone with food.\nSwallow the tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, or dissolve a tablet.\nNever crush or break a tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This can cause in death.\nYou should not stop using Roxicodone suddenly. Follow your doctor\'s instructions about tapering your dose.\nStore at room temperature, away from heat, moisture, and light. Keep track of your medicine. Roxicodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.\nDo not keep leftover opioid medication. Just one dose can cause death in someone using Roxicodone accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.\n Detailed Roxicodone dosage information\nWhat happens if I miss a dose?\nSince Roxicodone is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Roxicodone could be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.\nYour doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don\'t wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.\nAnyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.\n','You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines. Tell your doctor if you also use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C.\nOxycodone can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:\ncold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic (\"water pill\");\nmedicines for motion sickness, irritable bowel syndrome, or overactive bladder;\nother opioids - opioid pain medicine or prescription cough medicine;\na sedative like Valium - diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and others;\ndrugs that make you sleepy or slow your breathing - a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness; or\ndrugs that affect serotonin levels in your body - a stimulant, or medicine for depression, Parkinson\'s disease, migraine headaches, serious infections, or nausea and vomiting.\nThis list is not complete and many other drugs may affect Roxicodone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Roxicodone drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Roxicodone: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nOxycodone can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.\nCall your doctor at once if you have:\nnoisy breathing, sighing, shallow breathing, breathing that stops during sleep;\na slow heart rate or weak pulse;\na light-headed feeling, like you might pass out;\nconfusion, unusual thoughts or behavior;\nseizure (convulsions);\nlow cortisol levels - nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or\nhigh levels of serotonin in the body - agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.\nSerious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.\nCommon Roxicodone side effects may include:\ndrowsiness, headache, dizziness, tiredness; or\nconstipation, stomach pain, nausea, vomiting.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Roxicodone side effects (more detail)\n','Roxicodone (oxycodone) is an opioid pain medication sometimes called a narcotic.\nRoxicodone is strong prescription pain medicine used to treat moderate to severe pain. It is used to manage pain when other treatments such as non-opioid pain medicines are unable to control the pain or you cannot tolerate alternate treatments.\nPatients with chronic pain should have their dosage given on an around-the-clock basis to prevent the reoccurrence of pain rather than treating the pain after it has occurred.\nRoxicodone is supplied as an immediate-release tablet and is available in 5 mg, 15 mg, and 30 mg strengths.\nChanging brands of oxycodone from immediate-release tablets to extended-release tablets must be accompanied by close observation checking for signs of excessive drowsiness or slow breathing.\n','You should not use Roxicodone if you have severe asthma or breathing problems, a bowel blockage, or have narrowing of the stomach or intestines.\nMISUSE OF ROXICODONE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.\nTaking Roxicodone during pregnancy may cause life-threatening withdrawal symptoms in the newborn.\nFatal side effects can occur if you use Roxicodone with alcohol, or with other drugs that cause drowsiness or slow your breathing.\nBefore taking this medicine\nYou should not use Roxicodone if you are allergic to oxycodone, or if you have:\nsevere asthma or breathing problems; or\na blockage in your stomach or intestines.\nYou should not use Roxicodone unless you are already using a similar opioid medicine and are tolerant to it.\nMost brands of oxycodone are not approved for use in people under 18.\nTo make sure Roxicodone is safe for you, tell your doctor if you have:\nbreathing problems, sleep apnea;\na head injury, or seizures;\ndrug or alcohol addiction, or mental illness;\nliver or kidney disease;\nurination problems; or\nproblems with your gallbladder, pancreas, or thyroid.\nIf you use oxycodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.\nAsk a doctor before using Roxicodone if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.\n','Do not drink alcohol. Dangerous side effects or death could occur.\nAvoid driving or operating machinery until you know how Roxicodone will affect you. Dizziness or severe drowsiness can cause falls or other accidents.\nAvoid medication errors. Always check the brand and strength of oxycodone you get from the pharmacy.\n'),(778,'ruconest','Use Ruconest exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nRuconest is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.\nRuconest is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine. Ask your pharmacist what type of diluent can safely be mixed with this medicine powder.\nWash your hands before mixing the medicine or preparing your injection.\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\nAfter mixing Ruconest, store in the refrigerator and use within 8 hours. Do not freeze.\nMixed medicine should be used right away if you keep it at room temperature.\nc1 esterase inhibitor doses are based on weight. You may need to use two vials of Ruconest powder to make up a single dose. Carefully follow all mixing instructions provided with your medicine.\nEach single-use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.\nThis medicine must be injected slowly, and the IV infusion should take about 5 minutes to complete.\nA single dose of Ruconest is usually enough to treat an angioedema attack. You may need to use a second dose if your symptoms do not get better after just one dose.\nStore the unmixed dry powder in a refrigerator or in a dark cool place. Keep the medicine protected from light and do not allow it to freeze. Throw away any unused vial after the expiration date on the label has passed.\n Detailed Ruconest dosage information\nWhat happens if I miss a dose?\nSince Ruconest is used when needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using this medicine.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with c1 esterase inhibitor, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Ruconest drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Ruconest: rash or hives; chest tightness, wheezing, difficult breathing; blue-colored lips or gums; fast heartbeats; feeling like you might pass out; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsudden numbness or weakness (especially on one side of the body);\nsudden severe headache, slurred speech, problems with vision or balance; or\npain, swelling, warmth, or redness in one or both legs.\nCommon Ruconest side effects may include:\nheadache;\ndiarrhea; or\nnausea.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Ruconest side effects (more detail)\n','Ruconest (c1 esterase inhibitor) is a manmade form of the c1 esterase inhibitor protein that occurs naturally in the bloodstream and helps control swelling in the body. People with a condition called Hereditary Angioedema do not have enough of this protein. Hereditary Angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.\nRuconest is an injectable medicine used to treat acute angioedema attacks in in adult and adolescent patients with Hereditary Angioedema.\nRuconest is for use in adults and children who are at least 13 years old.\n','You should not use Ruconest if you are allergic to rabbits or rabbit products (meat, fur, pelt).\nYou should not use Ruconest if you have experienced life-threatening immediate hypersensitivity reactions, including anaphylaxis, to this medicine or to any other C1 esterase inhibitor product.\nBefore taking this medicine\nYou should not use Ruconest if you are allergic to c1 esterase inhibitor, or:\nif you are allergic to rabbits or rabbit products (meat, fur, pelt); or\nif you have ever had a life-threatening allergic reaction to Ruconest or to another C1 esterase inhibitor (such as Berinert or Cinryze).\nTo make sure Ruconest is safe for you, tell your doctor if you have:\ncoronary artery disease (hardened arteries); or\na history of stroke or blood clot.\nThis medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether c1 esterase inhibitor passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.\nRuconest is not approved for use by anyone younger than 13 years old.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(779,'rybelsus','Usual Adult Dose for Diabetes Type 2:\nOral Tablets:\nInitial dose: 3 mg orally once a day for 30 days; then 7 mg orally once a day\n-Titration: If additional glycemic control is needed after receiving 7 mg/day for at least 30 days, may increase to 14 mg orally once a day\nMaintenance dose: 7 to 14 mg orally once a day\nMaximum dose: 14 mg/day (taking two 7 mg tablets to achieve a 14 mg dose is not recommended).\nUsual Adult Dose for Cardiovascular Risk Reduction:\nOral Tablets:\nInitial dose: 3 mg orally once a day for 30 days; then 7 mg orally once a day\n-Titration: If additional glycemic control is needed after receiving 7 mg/day for at least 30 days, may increase to 14 mg orally once a day\nMaintenance dose: 7 to 14 mg orally once a day\nMaximum dose: 14 mg/day (taking two 7 mg tablets to achieve a 14 mg dose is not recommended).\n Detailed Rybelsus dosage information\nWhat happens if I miss a dose?\nRybelsus: Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Rybelsus can slow your digestion, and it may take longer for your body to absorb any medicines you take by mouth.\nTell your doctor about all your other medicines, especially insulin or other diabetes medicine.\nOther drugs may interact with semaglutide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Rybelsus drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rybelsus: hives, itching; dizziness, fast heartbeats; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nvision changes;\nsigns of a thyroid tumor - swelling or a lump in your neck, trouble swallowing, a hoarse voice, feeling short of breath;\nsymptoms of pancreatitis - severe pain in your upper stomach spreading to your back, nausea with or without vomiting, fast heart rate;\nlow blood sugar - headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or\nkidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath.\nCommon Rybelsus side effects may include:\nnausea, vomiting, stomach pain, loss of appetite;\ndiarrhea; or\nconstipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rybelsus side effects (more detail)\n','Rybelsus (semaglutide) is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. .\nRybelsus is usually given after other diabetes medicines have been tried without success.\nRybelsus is not for treating type 1 diabetes.\nRybelsus is supplied as a white to light yellow, oval shaped tablet and is available in 3mg, 7mg, and 14mg strengths.\n','You should not use Rybelsus if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer, insulin-dependent diabetes, or diabetic ketoacidosis.\nCall your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.\nBefore taking this medicine\nYou should not use Rybelsus if you are allergic to semaglutide, or if you have:\nmultiple endocrine neoplasia type 2 (tumors in your glands);\na personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or\ndiabetic ketoacidosis (call your doctor for treatment).\nTo make sure Rybelsus is safe for you, tell your doctor if you have:\na stomach or intestinal disorder;\npancreatitis;\nkidney disease; or\neye problems caused by diabetes (retinopathy).\nIn animal studies, semaglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.\nSemaglutide may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Rybelsus can have long-lasting effects on your body. Avoid getting pregnant for at least 2 months after you stop using this medicine.\nYou should not breastfeed while using Rybelsus.\nRybelsus is not approved for use by anyone younger than 18 years old.\n',NULL),(780,'rydapt','Usual Adult Dose for Acute Myeloid Leukemia:\n50 mg orally twice a day at approximately 12 hour intervals on Days 8 to 21 of each cycle of induction AND on Days 8 to 21 of each cycle of consolidation.\nComments:\n-This drug is not indicated as a single-agent induction therapy for acute myeloid leukemia (AML) patients.\n-Information on FDA-approved tests for the detection of FLT3 mutation in AML is available at: http://www.fda.gov/CompanionDiagnostics.\nUse: In combination with standard cytarabine and daunorubicin induction and high-dose cytarabine consolidation, treatment of newly diagnosed AML who are FLT3 mutation-positive as detected by a FDA approved test.\nUsual Adult Dose for Systemic Mastocytosis:\n100 mg orally twice a day at approximately 12 hour intervals\nDuration of Therapy: Until disease progression or unacceptable toxicity occurs.\nComments: Monitor for toxicity at least weekly for the first 4 weeks, every other week for the next 8 weeks, and monthly thereafter while on treatment.\nUses: Treatment of aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).\nUsual Adult Dose for Leukemia:\n100 mg orally twice a day at approximately 12 hour intervals\nDuration of Therapy: Until disease progression or unacceptable toxicity occurs.\nComments: Monitor for toxicity at least weekly for the first 4 weeks, every other week for the next 8 weeks, and monthly thereafter while on treatment.\nUses: Treatment of aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).\n Detailed Rydapt dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.\nOther drugs may interact with midostaurin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Rydapt drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rydapt: hives, warmth, redness, or tingly feeling; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\npain or sores in or around your mouth, redness inside your mouth, sore throat;\nsudden chest pain or discomfort, wheezing, dry cough, feeling short of breath;\nsigns of infection around where a needle was injected to give you other medicines - bruising, swelling, warmth, redness, oozing, or bleeding around the needle;\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or\nlow blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.\nCommon Rydapt side effects may include:\nlow blood cell counts, fever;\nbruising, nosebleeds;\nhigh blood sugar;\ninfection around a needle injection;\nmouth sores;\ncold symptoms such as stuffy nose, sneezing, sore throat;\ntrouble breathing;\nnausea, vomiting, stomach pain, constipation, diarrhea;\nmuscle or bone pain;\nheadache, feeling tired; or\nswelling in your hands, feet, or ankles.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rydapt side effects (more detail)\n','Rydapt (midostaurin) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.\nRydapt is used together with other cancer medicines to treat acute myeloid leukemia.\nRydapt is also used to treat certain rare blood disorders, including systemic mastocytosis with mast cell leukemia or other cancers affecting the blood, bone marrow, or lymphatic tissue.\n','Both men and women using Rydapt should use effective birth control to prevent pregnancy. Midostaurin can harm an unborn baby if the mother or father is using this medicine.\nBefore taking this medicine\nYou should not use Rydapt if you are allergic to midostaurin.\nTell your doctor if you have ever had:\nlung disease or breathing problems.\nYou may need to have a negative pregnancy test before starting this treatment.\nMidostaurin can harm an unborn baby or cause birth defects if the mother or the father is using Rydapt.\nIf you are a woman, do not use midostaurin if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 4 months after your last dose. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of midostaurin on the baby.\nIf you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.\nTell your doctor right away if a pregnancy occurs while either the mother or the father is using Rydapt.\nRydapt may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because midostaurin can harm an unborn baby.\nYou should not breastfeed while using Rydapt and for at least 4 months after your last dose.\nRydapt is not approved for use by anyone younger than 18 years old.\nHow should I take Rydapt?\nTake Rydapt exactly as prescribed by your doctor. Your doctor will perform a test to make sure Rydapt is the right treatment for your condition.\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nRydapt is usually taken 2 times per day (once every 12 hours) with food.\nTake your doses at regular intervals to keep a steady amount of the drug in your body at all times.\nYou may be given medication to prevent nausea or vomiting while you are taking this medicine.\nIf you vomit shortly after taking Rydapt, do not take another dose. Wait until your next scheduled dose time to take the medicine again.\nDo not crush or open a Rydapt capsule.\nYou may need frequent blood tests (every 1 to 4 weeks). Rydapt is usually given until your body no longer responds to the medication.\nUse all medications as directed by your doctor. Read the instructions provided with each medication. Do not change your doses or medication schedule without your doctor\'s advice.\nStore the capsules in the original container at room temperature, away from moisture and heat.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(781,'rytary','Usual Adult Dose for Parkinson\'s Disease:\nOptimum dosage is determined by careful individual titration: All doses expressed as CARBIDOPA-LEVODOPA\nRytary extended-release capsules:\n-Initial dose (levodopa-naive): 23.75 mg-95 mg orally 3 times a day for 3 days; on the fourth day, may increase to 36.25 mg-145 mg 3 times a day\n-Dosing interval may be increased up to a maximum of 5 times a day, if tolerated\n-Maximum daily dose: 612.5 mg-2450 mg\nConversion from IMMEDIATE-RELEASE carbidopa-levodopa to Rytary: These recommended starting doses should be divided and given three times a day:\n-For patients receiving levodopa 400 to 549 mg/day: total daily dose of levodopa in Rytary - 855 mg/day\n-For patients receiving levodopa 550 to 749 mg/day: total daily dose of levodopa in Rytary - 1140 mg/day\n-For patients receiving levodopa 750 to 949 mg/day: total daily dose of levodopa in Rytary - 1305 mg/day\n-For patients receiving levodopa 950 to 1249 mg/day: total daily dose of levodopa in Rytary - 1755 mg/day\n-For patients receiving levodopa equal or greater than 1250 mg/day: Rytary levodopa dose should be 2205 or 2340 mg/day\nComments:\n-Peripheral dopa decarboxylase is saturated by carbidopa at approximately 70 to 100 mg/day; patient\'s receiving less than this amount of carbidopa are more likely to experience nausea and vomiting; experience with carbidopa doses greater than 200 mg/day is limited.\n-Rytary products are not interchangeable with other carbidopa-levodopa products; for patients receiving carbidopa-levodopa plus catechol-O-methyl transferase (COMT) inhibitors, the initial recommended total daily dose of levodopa may need to be increased.\nUse: For the treatment of the symptoms of idiopathic Parkinson\'s disease, postencephalitic parkinsonism, and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication and/or manganese intoxication.\n Detailed Rytary dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with carbidopa and levodopa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Rytary drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Rytary: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\nworsening of tremors (uncontrolled shaking);\nsevere or ongoing vomiting or diarrhea;\nconfusion, hallucinations, unusual changes in mood or behavior;\ndepression or suicidal thoughts; or\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.\nSome people taking Rytary have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.\nYou may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.\nYou may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.\nCommon Rytary side effects may include:\njerky or twisting muscle movements;\nheadache, dizziness;\nlow blood pressure (feeling light-headed);\nsleep problems, strange dreams;\ndry mouth;\nmuscle contractions; or\nnausea, vomiting, constipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Rytary side effects (more detail)\n','Rytary contains a combination of carbidopa and levodopa.\nRytary extended release capsules are used to treat symptoms of Parkinson\'s disease, such as muscle stiffness, tremors, spasms, and poor muscle control. Parkinson\'s disease may be caused by low levels of a chemical called dopamine (DOE pa meen) in the brain.\nRytary is also used to treat Parkinson symptoms caused by carbon monoxide carbon monoxide poisoning or manganese intoxication.\n','You should not use Rytary if you have narrow-angle glaucoma.\nDo not use Rytary if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.\nBefore taking this medicine\nYou should not use Rytary if you are allergic to carbidopa or levodopa, or if you have:\nnarrow-angle glaucoma.\nDo not use Rytary if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.\nTo make sure Rytary is safe for you, tell your doctor if you have:\nheart disease, high blood pressure, or heart attack;\nliver or kidney disease;\nan endocrine (hormonal) disorder;\nasthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;\na stomach or intestinal ulcer;\nopen-angle glaucoma; or\ndepression, mental illness, or psychosis.\nPeople with Parkinson\'s disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.\nTell your doctor if you are pregnant or breastfeeding.\nHow should I take Rytary?\nTake Rytary exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nIf you already take levodopa, you must stop taking it at least 12 hours before you start taking Rytary.\nRytary can be taken with or without food. Take your doses at regular intervals to keep a steady amount of the drug in your body at all times.\nSwallow the capsule whole and do not crush, chew, break, or open it.\nIt may take up to several weeks of using Rytary before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after a few weeks of treatment. Also tell your doctor if the effects of this medication seem to wear off quickly in between doses.\nIf you use Rytary long-term, you may need frequent medical tests.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Rytary.\nDo not stop using Rytary suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.\nStore at room temperature away from moisture, heat, and light.\n','Avoid driving or hazardous activity until you know how Rytary will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.\nAvoid taking iron supplements or eating a diet that is high in protein (protein sources include meat, eggs, and cheese). These things can make it harder for your body to digest and absorb carbidopa and levodopa. Talk with your doctor or dietitian about the best foods to eat while you are taking this medicine.\n'),(782,'sabril','Usual Adult Dose for Seizure Prophylaxis:\nInitial dose: 1 g orally daily (administered as one 500 mg orally 2 times daily) with or without food\nThe total daily dose may be increased in 500 mg increments at weekly intervals depending on response.\nRecommended dose: 3 g orally daily (1.5 g orally 2 times daily)\nA 6 g daily dose has not been shown to confer additional benefit compared to the 3 g daily dose and is associated with an increased incidence of adverse events.\nApproved indication: For adults and children 10 years of age and older as adjunctive therapy for refractory complex partial seizures (CPS) who have inadequately responded to several alternative treatments and for whom the potential benefits outweigh the risk of vision loss. Sabril is not indicated as a first line agent for complex partial seizures.\nUsual Pediatric Dose for Epilepsy:\nInfantile Spasms:\n1 month to 2 years of age:\nInitial dose: 50 mg/kg/day of vigabatrin oral solution given in two divided doses with or without food. The dose may be titrated by 25 to 50 mg/kg/day increments every 3 days up to a maximum of 150 mg/kg/day.\nThe entire contents of the appropriate number of packets (500 mg/packet) of powder should be emptied into an empty cup, and should be dissolved in 10 mL of cold or room temperature water per packet using the 10 mL oral syringe supplied with the medication. The concentration of the final solution is 50 mg/mL.\nEach individual dose should be prepared immediately before use and administered cold or at room temperature.\nApproved indication: As monotherapy for pediatric patients who are 1 month to 2 years of age with infantile spasms (IS) and for whom the potential benefits outweigh the potential risk of vision loss.\nUsual Pediatric Dose for Seizure Prophylaxis:\n10 to 16 years of age and 25 to 60 kg:\n-Initial dose: 500 mg orally daily (administered as one 250 mg orally 2 times daily) with or without food\n-Maintenance dose: Total daily dose may be increased at weekly intervals to 2 gm orally daily (1 g orally 2 times daily).\n-Patients weighing more than 60 kg should be dosed according to adult guidelines.\nApproved indication: For children 10 to 16 years of age as adjunctive therapy for refractory complex partial seizures (CPS) who have inadequately responded to several alternative treatments and for whom the potential benefits outweigh the risk of vision loss. Vigabatrin is not indicated as a first line agent for complex partial seizures.\n Detailed Sabril dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nCall your doctor for instructions if your baby is taking Sabril and misses a dose, takes only part of a dose, or spits up or vomits after taking the medicine.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe drowsiness or dizziness, confusion, trouble speaking, feeling agitated or irritable, unusual thoughts or behavior, increased seizures, slow heart rate, weak or shallow breathing, or fainting.\n','Other drugs may interact with vigabatrin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Sabril drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Sabril (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).\nTaking vigabatrin can cause permanent vision loss. Tell your doctor right away about any changes in your vision. If a child is taking Sabril: Tell the doctor right away if the child shows signs of vision changes, such as bumping into things or being easily startled or surprised.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nincreased or worsening seizures;\nany change in your vision, no matter how mild;\nunusual or involuntary eye movements;\nsevere drowsiness, fussiness, or feeding problems (in a baby taking vigabatrin);\nnumbness, tingling, or burning pain in your hands or feet;\nweight gain with or without swelling;\nsigns of an ear infection - fever, ear pain or full feeling, trouble hearing, drainage from the ear, fussiness in a child; or\nlow red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.\nSome babies treated with Sabril have had abnormal brain changes seen on magnetic resonance imaging (MRI). It is not known if these changes are caused by vigabatrin or if they are harmful. Tell any doctor who treats your baby that the child is taking this medicine.\nCommon Sabril side effects may include:\nblurred vision or other eye problems;\ndrowsiness, dizziness, feeling tired;\nproblems with walking or coordination;\ntremors or shaking;\naggressive behavior;\nconfusion, problems with thinking or memory;\nweight gain;\njoint pain;\ncold symptoms such as stuffy nose, sneezing, sore throat; or\n(in babies) fussiness, ear infection, cough, breathing problems.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sabril side effects (more detail)\n','Sabril (vigabatrin) is an anti-epileptic medicine, also called an anticonvulsant.\nSabril is used in combination with other medications to treat complex partial seizures in adults and children who are at least 10 years old. The powder for oral solution is used to treat infantile spasms in babies and children between the ages of 1 month and 2 years.\nSabril can cause serious side effects and should be used only by people who have been unable to control their seizures with several other medications.\n','Taking Sabril can cause permanent vision loss, even after you stop using this medicine. Tell your doctor if you have any vision problems, such as retinitis or glaucoma and advise your doctor right away about any changes in your vision. You must have frequent eye exams before, during, and shortly after taking this medicine.\nTo be sure Sabril is not causing harmful effects on your vision, you will need a thorough eye exam before you start taking the medication and then every 3 months during treatment, even if your vision seems normal. If you ever stop taking this medicine, you may still need to have eye exams every 3 to 6 months after your treatment ends. Do not miss any follow-up visits to your doctor.\nSome babies treated with vigabatrin have had abnormal brain changes seen on magnetic resonance imaging (MRI). Tell any doctor who treats your baby that the child is taking this medicine.\nSome people have thoughts about suicide while taking seizure medication. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nSabril should be used only by people who have been unable to control their seizures with several other medications.\nBefore taking this medicine\nSome people taking Sabril have developed vision problems within weeks to years after starting treatment. Vision loss caused by vigabatrin may be permanent, and you may notice only mild symptoms at first. Talk to your doctor about this possibility.\nSabril is available only from a certified pharmacy under a special program. You must be registered in the program and agree to have vision exams before, during, and shortly after taking vigabatrin. Be sure you understand the risks and benefits of taking this medicine.\nYou should not use Sabril if you are allergic to vigabatrin.\nTo make sure Sabril is safe for you, tell your doctor if you (or the child taking this medicine) have ever had:\nvision problems;\nkidney disease;\nanemia (low red blood cells); or\ndepression, a mood disorder, mental illness, or suicidal thoughts or actions.\nSome people have thoughts about suicide while taking Sabril. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nDo not start or stop taking seizure medication during pregnancy without your doctor\'s advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant.\nIf you are pregnant, your name may be listed on a pregnancy registry to track the effects of vigabatrin on the baby.\nYou should not breastfeed while you are using Sabril.\nDo not give this medicine to a child without medical advice.\nHow should I take Sabril?\nTake Sabril exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nYou may take Sabril with or without food.\nSabril powder must be mixed only with water, and can be given to the child with a meal. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nAnyone taking Sabril can develop vision problems that could get worse, even after you stop using this medicine. The more you take this medicine, the more likely you are to develop severe vision problems.\nYou will need a thorough eye exam before you start taking this medicine and then every 3 months during treatment, even if your vision seems normal. Eye exams may not fully prevent vision damage, but they will help your doctor decide whether to change your treatment plan. Stay alert to any changes in your vision and report them to your doctor right away.\nIf you stop taking Sabril, you should have another eye exam about 3 to 6 months after your last dose.\nIt may be more difficult to test vision in a baby or young child. However, your doctor may still prescribe vigabatrin for the child if the benefit of preventing seizures outweighs any risk. Tell the doctor right away if you think your child\'s vision may be changing.\nCall your doctor if your complex partial seizures do not improve after 3 months of treatment, or if your baby\'s infantile spasms do not improve after 2 to 4 weeks of treatment.\nDo not stop using Sabril suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor\'s instructions about tapering your dose.\nStore in the original container at room temperature away from moisture and heat.\n','Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(783,'salbutamol','This section provides information on the proper use of a number of products that contain albuterol.  It may not be specific to Salbutamol. Please read with care.\nUse this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.\nThe albuterol inhalation solution (eg, Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.\nTo use the inhalation solution in the nebulizer:\nUse one container of solution or mix the exact amount of solution using the dropper provided for each dose.\nPlace the inhalation solution in the medicine reservoir or nebulizer cup on the machine.\nConnect the nebulizer to the face mask or mouthpiece.\nUse the face mask or mouthpiece to breathe in the medicine.\nUse the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone.\nClean all the parts of the nebulizer after each use.\nThe albuterol inhalation aerosol (eg, ProAir® HFA, Proventil® HFA) and albuterol inhalation powder (eg, ProAir® Digihaler™, ProAir® Respiclick®) are used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you or your child use the inhaler to make sure you are using it properly.\nTo use the inhalation aerosol:\nThe inhaler should be at room temperature before you use it.\nInsert the metal canister firmly and fully into the actuator. This actuator should not be used with other inhaled medicines.\nRemove the cap and look at the mouthpiece to make sure it is clean.\nPoint the inhaler away from your face. Shake the inhaler well and test spray it in the air 3 times for ProAir® HFA or 4 times for Proventil® HFA before using it for the first time or if the inhaler has not been used for more than 2 weeks.\nTo inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.\nOpen your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister.\nHold your breath for about 10 seconds, then breathe out slowly.\nIf you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler.\nWhen you have finished all of your doses, rinse your mouth with water and spit the water out.\nClean the inhaler mouthpiece at least once a week with warm running water for 30 seconds, and air dry it completely.\nIf you need to use the inhaler before it is completely dry, shake off the excess water, replace the canister, and spray it 2 times in the air away from the face. Use your regular dose.\nAfter using the inhaler, wash the mouthpiece again and dry it completely.\nIf the mouthpiece becomes blocked, washing it will help.\nThe Proventil® HFA inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The counter will turn red when there are only 20 doses left, to remind you to refill your prescription.\nTo use the inhalation powder:\nTake the inhaler from the foil pouch before you use it for the first time.\nThe inhaler provides about 200 inhalations. The dose counter will change to red when there are \"20\" doses left. Call your doctor or pharmacist for a refill of prescription or medicine.\nMake sure the cap is closed before using this medicine. Do not open the cap unless you are going to use it.\nHold the inhaler upright as you open the cap fully until you hear a \"click\". Your inhaler is now ready to use.\nTo inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it.\nBreathe in through your mouth as deeply as you can until you have taken a full deep breath.\nDo not block the vent above the mouthpiece with your lips or fingers.\nHold your breath for about 10 seconds or as long as you comfortably can.\nRemove the inhaler from your mouth and check the dose counter to make sure you received the medicine.\nClose the cap firmly over the mouthpiece after using the inhaler. Always close the cap after each use.\nIf you are supposed to use more than one puff, repeat these steps for the second puff, starting with opening the cap fully.\nDo not use a spacer or volume holding chamber together with the ProAir® Digihaler™.\nKeep the inhaler clean and dry at all times. Do not wash or put any part of the inhaler in water. Replace the ProAir® Digihaler™ if it has been washed or placed in water.\nIf you need to clean the mouthpiece, wipe it gently with a dry cloth or tissue.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.\nThe amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.\nFor inhalation aerosol dosage form (inhaler):\nFor treatment or prevention of bronchospasm:\nAdults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.\nChildren younger than 4 years of age—Use and dose must be determined by your child\'s doctor.\nFor prevention of exercise-induced bronchospasm:\nAdults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.\nChildren younger than 4 years of age—Use and dose must be determined by your child\'s doctor.\nFor inhalation powder dosage form (inhaler):\nFor treatment or prevention of bronchospasm:\nAdults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.\nChildren younger than 4 years of age—Use and dose must be determined by your child\'s doctor.\nFor prevention of exercise-induced bronchospasm:\nAdults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.\nChildren younger than 4 years of age—Use and dose must be determined by your child\'s doctor.\nFor inhalation solution dosage form (used with a nebulizer):\nFor prevention of bronchospasm:\nAdults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed.\nChildren 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed.\nChildren younger than 2 years of age—Use and dose must be determined by your child\'s doctor.\nMissed dose\nIf you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.\nStorage\nKeep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.\nStore unopened vials of this medicine at room temperature, away from heat and direct light. Do not freeze. An open vial of medicine must be used right away.\nStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.\nKeep out of the reach of children.\nDo not keep outdated medicine or medicine no longer needed.\nAsk your healthcare professional how you should dispose of any medicine you do not use.\nStore the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.\nStore Proventil® HFA inhaler with the mouthpiece down.\nThrow away the ProAir® Digihaler™ or ProAir® Respiclick® 13 months after opening the foil pouch, when the dose counter reaches \"0\", or after the expiration date, whichever comes first.\n Detailed Albuterol dosage information\n',NULL,'Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.\nCheck with your doctor immediately if any of the following side effects occur:\nMore common\nFast, irregular, pounding, or racing heartbeat or pulse\nshakiness in the legs, arms, hands, or feet\ntrembling or shaking of the hands or feet\nLess common\nBladder pain\nbloody or cloudy urine\nchest discomfort or pain\nchills\ncough\ncough producing mucus\ndiarrhea\ndifficult or labored breathing\ndifficulty with swallowing\ndizziness\nfeeling of warmth\nfever\nfrequent urge to urinate\nhives, itching, or skin rash\nhoarseness\nloss of appetite\nlower back or side pain\nnausea\npuffiness or swelling of the eyelids or around the eyes, face, lips, or tongue\nredness of the face, neck, arms, and occasionally, upper chest\nrunny nose\nsore throat\nstomach pain\nswollen, painful, or tender lymph glands in the neck, armpit, or groin\ntightness in the chest\nunusual tiredness or weakness\nRare\nHives or welts\nlarge, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals\nnoisy breathing\nswelling of the mouth or throat\nIncidence not known\nAgitation\narm, back, or jaw pain\nchest tightness or heaviness\nconfusion\ndecreased urine\ndizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position\ndrowsiness\ndry mouth\nextra heartbeat\nfainting\nflushed, dry skin\nfruit-like breath odor\nheadache\nincreased hunger\nincreased thirst\nincreased urination\nirritability\nlightheadedness\nmuscle pain or cramps\nnervousness\nnightmares\nnumbness or tingling in the hands, feet, or lips\npounding in the ears\nrapid, deep breathing\nrestlessness\nseeing, hearing, or feeling things that are not there\nseizures\nslow or fast heartbeat\nstomach cramps\nsweating\nunexplained weight loss\nunusual feeling of excitement\nvomiting\nSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:\nMore common\nBody aches or pain\ncongestion\nvoice changes\nLess common\nDifficult, burning, or painful urination\nearache\nheadache, severe and throbbing\nmuscle or bone pain\npain\nredness or swelling in the ear\nredness, swelling, or soreness of the tongue\nsneezing\nstuffy nose\nswelling\ntenderness\ntrouble in holding or releasing urine\ntrouble sleeping\nRare\nSleepiness or unusual drowsiness\nIncidence not known\nBad, unusual, or unpleasant (after) taste\nchange in taste\nfeeling of constant movement of self or surroundings\ngagging\nrough, scratchy sound to voice\nsensation of spinning\ntightness in the throat\nOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.\nCall your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.\n Albuterol side effects (more detail)\n','Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. It is also used to prevent bronchospasm caused by exercise.\nAlbuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.\nThis medicine is available only with your doctor\'s prescription.\n','It is very important that your doctor check your or your child\'s progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.\nThis medicine should not be used together with other similar inhaled medicines, such as isoproterenol (Isuprel®), levalbuterol (Xopenex™), metaproterenol (Alupent®), pirbuterol (Maxair®), or terbutaline (Brethaire®).\nThis medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. This may be life-threatening. Check with your doctor right away if you or your child have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.\nTalk to your doctor or get medical help right away if:\nYour symptoms do not improve or they become worse after using this medicine.\nYour inhaler does not seem to be working as well as usual and you need to use it more often.\nYou or your child may also be taking an antiinflammatory medicine, such as a steroid (cortisone-like medicine), together with this medicine. Do not stop taking the antiinflammatory medicine, even if your asthma seems better, unless your doctor tells you to.\nAlbuterol may cause serious types of allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Check with your doctor right away if you or your child develop a skin rash, hives, itching, trouble breathing or swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.\nHypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you or your child have more than one of the following symptoms: convulsions (seizures), decreased urine, dry mouth, increased thirst, irregular heartbeat, loss of appetite, mood changes, muscle pain or cramps, nausea, vomiting, numbness or tingling in the hands, feet, or lips, shortness of breath, or unusual tiredness or weakness.\nDo not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.\n',NULL),(784,'salmeterol','General\nWhen initiating salmeterol alone or in fixed combination with fluticasone, discontinue regular use of short-acting, oral or inhaled β2-agonists;     use a short-acting, inhaled β2-agonist, not salmeterol (alone or in fixed combination with fluticasone), to relieve acute symptoms such as shortness of breath.    \nIncreasing use of short-acting, inhaled β2-agonists is a marker of deteriorating asthma and failure to respond to a previously effective dosage is often a sign of asthma destabilization.         Extra/increased doses of salmeterol alone or in fixed combination with fluticasone are not recommended.         (See Deterioration of Disease and Acute Episodes under Cautions.) Consult clinician.  \nAdministration\nOral Inhalation\nAdminister by oral inhalation using a special oral inhaler (Diskus device) that delivers powdered salmeterol xinafoate alone (Serevent Diskus) or in fixed combination with fluticasone (Advair Diskus, AirDuo RespiClick) or using an inhalation aerosol containing salmeterol in fixed combination with fluticasone (Advair HFA) via an oral aerosol inhaler with hydrofluoroalkane (HFA) propellant.   \nAdminister twice daily, approximately every 12 hours.    \nInhalation Powder\nHold the Diskus device in one hand, put the thumb of the other hand on the thumbgrip, and push the thumbgrip until the mouthpiece appears and snaps into position.   \nTo release powdered drug into the exit port, hold the inhaler in a level, horizontal position and depress the lever on the Diskus in a direction away from the patient.   \nTo avoid releasing and wasting additional doses of the drug, do not close the Diskus device, play with the lever, or advance the lever more than once.   A dose counter will advance each time the lever is depressed.   \nExhale completely, place the mouthpiece of the inhaler between the lips, and inhale deeply and rapidly through the inhaler with a steady, even breath.     Remove the inhaler from the mouth and hold the breath for 10 seconds before slowly exhaling.   \nDo not exhale into the Diskus device.     \nDo not use another dose from the Diskus device if the patient does not feel or taste the drug. \nClose the inhalation device and reset for the next dose by sliding the thumbgrip toward the patient as far as it will go.    Do not wash the inhaler.    Do not take inhaler apart.     \nDiscard the inhaler when every blister of salmeterol alone or in fixed combination with fluticasone has been used.     Alternatively, discard the inhaler 6 or 4 weeks after removal of salmeterol alone or in fixed combination with fluticasone, respectively, from its foil overwrap pouch.    \nConsult manufacturer’s labeling for instructions on use of the AirDuo RespiClick oral inhaler.\nSpacer devices not recommended with the Serevent or Advair Diskus inhaler.    Spacer devices or volume holding chambers not recommended with the AirDuo RespiClick inhaler.\nRinse the mouth without swallowing after inhalation of salmeterol in fixed combination with fluticasone propionate.   \nSalmeterol/Fluticasone Inhalation Aerosol\nUse the inhalation aerosol only with the actuator supplied with the product.\nShake the oral aerosol inhaler well for 5 seconds before each inhalation.  Test spray inhaler 4 times into the air (away from face) before initial use, and shake well for 5 seconds before each spray.  If inhaler not used for >4 weeks or if inhaler was dropped, test spray inhaler twice into the air (away from face) and shake well for 5 seconds before each spray. \nRemove cap covering mouthpiece of the aerosol inhaler. Look for foreign objects inside inhaler prior to use and check to see that canister is fully seated within actuator.\nAfter exhaling as completely as possible, place mouthpiece of inhaler well into mouth and close lips firmly around it. Inhale deeply through mouth while actuating inhaler. Remove mouthpiece from mouth and hold breath for as long as possible (up to 10 seconds) and exhale slowly. It is recommended that 30 seconds elapse between inhalations. After inhalation, rinse mouth and spit out water. \nClean the aerosol inhaler by wiping the opening where medicine sprays out of metal canister and mouthpiece with a dry cotton swab and dampened tissue, respectively, at least once a week after evening dose.  Allow actuator to air-dry overnight.\nWhen dose counter on the aerosol inhaler reads “020,” recommend that the patient contact the pharmacy for a refill or consult clinician to determine need for a refill. Discard inhaler when the dose counter reads “000.” Never alter or remove dose counter from canister.\nDosage\nAvailable as salmeterol xinafoate; dosage expressed in terms of salmeterol.\nEach blister in the Serevent Diskus device contains 50 mcg of salmeterol inhalation powder; however, precise amount of drug delivered to lungs with each activation of the device depends on factors such as patient’s inspiratory flow.\nEach blister in the Advair Diskus device contains 50 mcg of salmeterol and 100, 250, or 500 mcg of fluticasone propionate; however, precise amount of each drug delivered to lungs with each activation of device depends on factors such as patient’s inspiratory flow.\nEach actuation of the AirDuo RespiClick device contains 14 mcg of salmeterol and 55, 113, or 232 mcg of fluticasone propionate; however, precise amount of each drug delivered to the lungs with each actuation of the device depends on factors such as the patient’s inspiratory flow.\nCommercially available AirDuo RespiClick oral inhaler delivers 60 actuations.\nEach actuation of the Advair HFA oral aerosol inhaler delivers 25 mcg of salmeterol and 50, 125, or 250 mcg of fluticasone propionate from the valve. Dosages in the fixed-combination inhalation aerosol are expressed in terms of drug delivered from the mouthpiece; each actuation of the inhaler delivers 21 mcg of salmeterol and 45, 115, or 230 mcg of fluticasone propionate from the mouthpiece.\nCommercially available Advair HFA inhalation aerosol delivers 60 or 120 metered sprays per 8- or 12-g canister, respectively.\nPediatric Patients\nAsthma\nSalmeterol\nChildren ≥4 years of age: 50 mcg (1 inhalation) twice daily.\nSalmeterol/Fluticasone Fixed Combination\nChildren ≥12 years of age: 42 mcg of salmeterol and 90, 230, or 460 mcg of fluticasone propionate (2 inhalations of Advair HFA) twice daily;   recommended initial dosage is based on patient’s asthma severity and current asthma therapy, including dosage of inhaled corticosteroids, as well as patient’s current control of asthma symptoms and risk of future exacerbations.\nIf control of asthma is inadequate after 2 weeks of therapy at the initial dosage, replacing the current strength of the fixed combination with a higher strength (higher strengths contain higher dosages of fluticasone only) may provide additional asthma control.\nChildren 4–11 years of age: 50 mcg of salmeterol and 100 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily in those inadequately controlled on an inhaled corticosteroid.\nChildren ≥12 years of age: 50 mcg of salmeterol and 100, 250, or 500 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily;   recommended initial dosage is based on patient’s asthma severity and current asthma therapy, including dosage of inhaled corticosteroids, as well as patient’s current control of asthma symptoms and risk of future exacerbations.\nChildren ≥12 years of age: 14 mcg of salmeterol and 55, 113, or 232 mcg of fluticasone propionate (1 inhalation of AirDuo RespiClick) twice daily at approximately the same time every day; recommended initial dosage is based on patient’s current asthma therapy and asthma severity. Usual recommended initial dosage is 14 mcg of salmeterol and 55 mcg of fluticasone propionate (1 inhalation) twice daily in patients not previously receiving inhaled corticosteroid therapy.\nAdministration of the inhalation powder of salmeterol in fixed combination with fluticasone more frequently than twice daily or exceeding 1 inhalation twice daily is not recommended. \nIf control of asthma is inadequate after 2 weeks of therapy at the initial dosage, replacing the current strength of the fixed combination with a higher strength (higher strengths contain higher dosages of fluticasone only) may provide additional asthma control.  \nExercise-induced Bronchospasm\nSalmeterol\nChildren ≥4 years of age: 50 mcg (1 inhalation) administered at least 30 minutes before exercise.\nAdults\nAsthma\nSalmeterol\n50 mcg (1 inhalation) twice daily.\nSalmeterol/Fluticasone Fixed Combination\n42 mcg of salmeterol and 90, 230, or 460 mcg of fluticasone propionate (2 inhalations) twice daily;    recommended initial dosage is based on patient’s asthma severity and current asthma therapy, including dosage of inhaled corticosteroids, as well as patient’s current control of asthma symptoms and risk of future exacerbations.\nIf control of asthma is inadequate after 2 weeks of therapy at the initial dosage, replacing the current strength of the fixed combination with a higher strength (higher strengths contain higher dosages of fluticasone only) may provide additional asthma control.\n50 mcg of salmeterol and 100, 250, or 500 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily;  recommended initial dosage is based on patient’s asthma severity and current asthma therapy, including dosage of inhaled corticosteroids, as well as patient’s current control of asthma symptoms and risk of future exacerbations.\n14 mcg of salmeterol and 55, 113, or 232 mcg of fluticasone propionate (1 inhalation of AirDuo RespiClick) twice daily at approximately the same time every day; recommended initial dosage is based on patient’s current asthma therapy and asthma severity. Usual recommended initial dosage is 14 mcg of salmeterol and 55 mcg of fluticasone propionate (1 inhalation) twice daily in patients not previously receiving inhaled corticosteroid therapy.\nAdministration of the inhalation powder of salmeterol in fixed combination with fluticasone more frequently than twice daily or exceeding 1 inhalation twice daily is not recommended. \nIf control of asthma is inadequate after 2 weeks of therapy at the initial dosage, replacing the current strength of the fixed combination with a higher strength (higher strengths contain higher dosages of fluticasone only) may provide additional asthma control. \nExercise-induced Bronchospasm\nSalmeterol\n50 mcg (1 inhalation) administered at least 30 minutes before exercise.\nCOPD\nSalmeterol\n50 mcg (1 inhalation) twice daily.\nSalmeterol/Fluticasone Fixed Combination\n50 mcg of salmeterol and 250 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily.\nUse of higher dosages or administration more frequently than twice daily not recommended.\nPrescribing Limits\nPediatric Patients\nAsthma\nSalmeterol\nChildren ≥4 years of age: Maximum 50 mcg (1 inhalation) twice daily.\nSalmeterol/Fluticasone Fixed Combination\nChildren or adolescents ≥12 years of age: Maximum 42 mcg of salmeterol and 460 mcg of fluticasone propionate (2 inhalations of Advair HFA) twice daily.\nChildren 4–11 years of age: Maximum 50 mcg of salmeterol and 100 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily.\nChildren or adolescents ≥12 years of age: Maximum 50 mcg of salmeterol and 500 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily.\nChildren or adolescents ≥12 years of age: Maximum 14 mcg of salmeterol and 232 mcg of fluticasone propionate (1 inhalation of AirDuo RespiClick) twice daily.\nExercise-induced Bronchospasm\nSalmeterol\nChildren ≥4 years of age: Maximum 50 mcg (1 inhalation) twice daily (every 12 hours).\nAdults\nAsthma\nSalmeterol\nMaximum 50 mcg (1 inhalation) twice daily.\nSalmeterol/Fluticasone Fixed Combination\nMaximum 42 mcg of salmeterol and 460 mcg of fluticasone propionate (2 inhalations) twice daily.\nMaximum 50 mcg of salmeterol and 500 mcg of fluticasone propionate (1 inhalation of Advair Diskus) twice daily.\nMaximum 14 mcg of salmeterol and 232 mcg of fluticasone propionate (1 inhalation of AirDuo RespiClick) twice daily.\nExercise-induced Bronchospasm\nSalmeterol\nMaximum 50 mcg (1 inhalation) twice daily (every 12 hours).\nCOPD\nSalmeterol\nMaximum 50 mcg (1 inhalation) twice daily.\nSalmeterol/Fluticasone Fixed Combination\nMaximum 50 mcg of salmeterol and 250 mcg of fluticasone propionate (1 inhalation) twice daily.\nSpecial Populations\nThe following information addresses dosage of salmeterol in special populations. When salmeterol is used in fixed combination with fluticasone propionate, dosage requirements for fluticasone propionate should be considered.  \nHepatic Impairment\nNo specific dosage recommendations at this time. Monitor patients receiving salmeterol alone or in fixed combination with fluticasone for increased drug exposure and systemic corticosteroid effects.    (See Hepatic Impairment under Cautions.)\nRenal Impairment\nNo specific dosage recommendations at this time.   \nGeriatric Patients\nDosage adjustments not recommended solely because of age in geriatric patients.  \n Detailed Salmeterol dosage information\n','The following information addresses potential interactions with salmeterol. When used in fixed combination with fluticasone, consider interactions associated with fluticasone.   No formal drug interaction studies have been performed to date with the fixed combinations.  \nSalmeterol and fluticasone are substrates for CYP3A4.   \nDrugs Affecting Hepatic Microsomal Enzymes\nPotential pharmacokinetic (increased peak plasma concentrations and AUC of salmeterol) and pharmacologic interactions (increased risk of adverse cardiovascular effects [e.g., QTc prolongation, palpitations, sinus tachycardia]) with concomitant use of potent CYP3A4 inhibitors.    Concomitant use of potent CYP3A4 inhibitors with salmeterol alone or in fixed combination with fluticasone not recommended.   \nSpecific Drugs\nDrug\nInteraction\nComments\nAtazanavir\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nβ2-Adrenergic agonists, short-acting\nPotential for increased adverse cardiovascular effects, but such effects less likely with a selective β2-adrenergic agonist like salmeterol     \nSafety of concomitant use of >8 inhalations of supplemental, short-acting β2-agonist therapy with salmeterol inhalation therapy not established \nβ-Adrenergic blocking agents\nPotential for antagonism of pulmonary effects and production of severe bronchospasm in patients with asthma or COPD     \nIf concomitant therapy required, consider cautious use of cardioselective β-adrenergic blocking agents   \nClarithromycin\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nCromolyn sodium\nNo apparent alteration in safety profile of salmeterol oral inhalation when administered concurrently      \nDiuretics, non-potassium-sparing\nPotential for additive hypokalemia and/or ECG changes, especially when recommended β-agonist dose is exceeded    \nClinical importance unknown; however, use concomitantly with caution    \nIndinavir\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nItraconazole\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nKetoconazole\nIncreased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects    \nConcomitant use not recommended   \nMAO inhibitors\nPotential for increased effect of salmeterol on the vascular system    \nExtreme caution recommended with concomitant therapy or within 2 weeks following discontinuance of an MAO inhibitor    \nNefazodone\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nNelfinavir\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nRitonavir\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nSaquinavir\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects   \nConcomitant use not recommended   \nTelithromycin\nPossible increased peak concentrations and AUC of salmeterol; possible increased risk of adverse cardiovascular effects    \nConcomitant use not recommended   \nTricyclic antidepressants\nPotential for increased effect of salmeterol on the vascular system    \nExtreme caution recommended with concomitant therapy or in patients receiving salmeterol within 2 weeks of discontinuance of these agents    \nXanthine derivatives\nPotential for increased cardiotoxic effects with concomitant administration of sympathomimetic agents and aminophylline but not theophylline   \nNo apparent alteration in safety profile of salmeterol oral inhalation observed when administered concurrently with theophylline in patients with asthma or COPD in clinical studies\n Salmeterol drug interactions (more detail)\n',NULL,'Bronchospasm in Asthma\nSalmeterol is used only concomitantly with long-term asthma controller therapy (e.g., inhaled corticosteroids) for treatment of asthma and prevention of bronchospasm in patients with reversible obstructive airway disease, including symptoms of nocturnal asthma.      \nMonotherapy with long-acting β2-adrenergic agonists (e.g., salmeterol) increases the risk of asthma-related death and may increase risk of asthma-related hospitalization in children and adolescents. Use of salmeterol for treatment of asthma without concomitant use of long-term asthma controller therapy (e.g., inhaled corticosteroids) is contraindicated.  (See Boxed Warning and also Asthma-related Death and Life-threatening Events under Cautions.)\nSalmeterol is used only as additional therapy in patients with asthma currently receiving long-term asthma controller therapy (e.g., inhaled corticosteroids) but whose disease is inadequately controlled with such therapy.  \nSalmeterol in fixed combination with fluticasone is used only in patients with asthma not responding adequately to long-term asthma controller therapy (e.g., inhaled corticosteroids) or whose disease severity warrants initiation of treatment with both an inhaled corticosteroid and a long-acting β2-adrenergic agonist.  \nOnce asthma control achieved and maintained, assess patient at regular intervals and step down therapy (e.g., discontinue salmeterol) if possible without loss of asthma control, and maintain patient on long-term asthma controller therapy (e.g., inhaled corticosteroids).   \nSalmeterol is not a substitute for corticosteroids; corticosteroid therapy should not be stopped or reduced in dosage when salmeterol is initiated.   (See Concomitant Anti-inflammatory Therapy under Cautions.)\nDo not use salmeterol alone or in fixed combination with fluticasone in patients with asthma adequately controlled on low or medium dosage of inhaled corticosteroids.  \nIn children and adolescents with asthma requiring addition of a long-acting β2-adrenergic agonist to an inhaled corticosteroid, generally use a fixed-combination preparation containing both an inhaled corticosteroid and a long-acting β2-adrenergic agonist to ensure compliance with both drugs.\nWhen separate administration of long-term asthma controller therapy (e.g., inhaled corticosteroids) and a long-acting β2-adrenergic agonist is clinically indicated, take appropriate steps to ensure compliance with both drugs. If compliance cannot be ensured, a fixed-combination preparation containing both an inhaled corticosteroid and a long-acting β2-adrenergic agonist is recommended.\nSalmeterol alone or in fixed combination with fluticasone not indicated for relief of acute bronchospasm.     (See Deterioration of Disease and Acute Episodes under Cautions.)\nExercise-induced Bronchospasm\nPrevention of exercise-induced bronchospasm.         \nUse as a single agent for prevention of exercise-induced bronchospasm may be clinically indicated in patients without persistent asthma.\nUse for prevention of exercise-induced bronchospasm may be clinically indicated in patients with persistent asthma; however, treatment of asthma should include long-term asthma controller therapy (e.g., inhaled corticosteroids).\nBronchospasm in COPD\nLong-term symptomatic treatment of reversible bronchospasm associated with moderate to severe COPD (e.g., FEV1 less than 80% of predicted), including chronic bronchitis and emphysema.        \nFixed combination with fluticasone as the inhalation powder (Advair Diskus) is used for maintenance treatment of airflow obstruction in COPD, including chronic bronchitis and/or emphysema; also used to reduce COPD exacerbations in patients with a history of exacerbations.\nNot indicated for relief of acute bronchospasm.   Use a short-acting inhaled β2-agonist intermittently (as needed) for acute symptoms of COPD.  (See Deterioration of Disease and Acute Episodes under Cautions.)\n',NULL,NULL),(785,'sandostatin','Usual Adult Dose for Carcinoid Tumor:\nInitial dose: 100 to 600 mcg per day, IV or subcutaneously, in 2 to 4 divided doses\nComments:\n-The median daily dose was 450 mcg; mean daily dose was 300 mcg.\n-Benefits were seen in doses from 50 mcg to 1500 mcg per day.\n-Experience with doses above 750 mcg per day is limited.\nLong-Acting depot formulation (Establish tolerability with short acting product for at least 2 weeks before using this formulation):\nInitial dose: 20 mg, IM (intragluteally), at 4 week intervals, for 2 months; continue with dose of regular octreotide for at least 2 weeks (at same dose patient was on before the switch)\nAfter 2 months:\n-If symptoms are controlled, consider reducing dose to 10 mg every 4 weeks\n-If symptoms are not adequately controlled, increase to 30 mg every 4 weeks\nMaximum dose: 30 mg every 4 weeks\nComments:\n-Failure to continue dosing of regular octreotide during a switch to the long acting formulation may exacerbate symptoms; some patients require 3 to 4 weeks of concomitant dosing.\nUse: Symptomatic treatment of patients with metastatic carcinoid tumors where it suppresses or inhibits the severe diarrhea and flushing episodes associated with the disease.\nUsual Adult Dose for Vasoactive Intestinal Peptide Tumor:\nInitial dose: 200 to 300 mcg per day, IV or subcutaneously, in 2 to 4 divided doses\nMaintenance dose: 150 to 750 mcg per day\n-Doses above 450 mcg per day are not usually required.\nLong-Acting depot formulation (Establish tolerability with short acting product for at least 2 weeks before using this formulation):\nInitial dose: 20 mg, IM (intragluteally), at 4 week intervals, for 2 months; continue with dose of regular octreotide for at least 2 weeks (at same dose patient was on before the switch)\nAfter 2 months:\n-If symptoms are controlled, consider reducing dose to 10 mg every 4 weeks\n-If symptoms are not adequately controlled, increase to 30 mg every 4 weeks\nComments:\n-Adjust dose for therapeutic response.\nUse: Long term treatment of the profuse watery diarrhea associated with Vasoactive Intestinal Peptide (VIP) secreting tumors.\nUsual Adult Dose for Acromegaly:\nInitial dose: 50 mcg, IV or subcutaneously, 3 times a day\nMaintenance dose: Usually 100 mcg, 3 times a day\nMaximum dose: 500 mcg, 3 times a day\nComments:\n-Starting at a low dose may help patients adapt to gastrointestinal adverse events.\n-Use IGF-1 (somatomedin C) levels, every 2 weeks, to guide titration.\n-Multiple growth hormone levels, zero to 8 hours after dosing, may permit more rapid dose titration.\n-Doses over 300 mcg per day seldom provide additional biochemical benefit.\nLong-Acting depot formulation (Establish tolerability with short acting product for at least 2 weeks before using this formulation):\nInitial dose: 20 mg, IM (intragluteally), at 4 week intervals, for 3 months\nAfter 3 months:\n-If GH is 1 ng/mL or less, IGF-1 normal, and clinical symptoms controlled: 10 mg, IM, every 4 weeks\n-If GH is 2.5 ng/mL or less and clinical symptoms controlled: 20 mg, IM, every 4 weeks\n-If GH is higher than 2.5 ng/mL and/or clinical symptoms uncontrolled: 30 mg, IM, every 4 weeks\n-If GH, IGF-1, or symptoms are not adequately controlled at 30 mg, may increase dose to 40 mg IM every 4 weeks\nMaximum dose: 40 mg, every 4 weeks\nComments:\n-The goal is growth hormone (GH) levels under 5 ng/mL, or IGF-1 levels under 1.9 U/mL (male) or 2.2 U/mL (female).\n-If increased doses do not provide additional benefit, reduce dose.\n-Check IGF-1 or growth hormone levels every 6 months.\n-For patients who have received irradiation: withdraw medication yearly for about 4 weeks (8 weeks for long-acting formulation) to assess disease activity; if growth hormone or IGF-1 increase and symptoms recur, resume therapy.\nUse: To reduce blood levels of growth hormone and IGF-1 (somatomedin C) in acromegaly patients who have had inadequate response to or cannot be treated with surgical resection or radiotherapy.\n Detailed Sandostatin dosage information\nWhat happens if I miss a dose?\nCall your doctor for instructions if you miss a dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\nOverdose symptoms may include severe upper stomach pain, diarrhea, weight loss, warmth or tingling, numbness or cold feeling, unexplained muscle pain, weakness, weak pulse, fainting, or slow breathing (breathing may stop).\n','Tell your doctor about all your other medicines, especially:\nbromocriptine (Cycloset, Parlodel);\ncyclosporine;\ninsulin or oral diabetes medicine; or\nheart or blood pressure medication.\nThis list is not complete. Other drugs may interact with octreotide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Sandostatin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Sandostatin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nsevere constipation;\nslow or uneven heartbeats;\nsigns of gallstones - fever, chills, nausea, vomiting, severe pain in your upper stomach spreading to your back, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);\nhigh blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor;\nlow blood sugar - headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or\nunderactive thyroid - extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain.\nCommon Sandostatin side effects may include:\ngallstones;\nnausea, vomiting, diarrhea, stomach pain, gas;\nheadache, back pain; or\ndizziness, tiredness.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sandostatin side effects (more detail)\n','Sandostatin (octreotide) is a man-made protein that is similar to a hormone in the body called somatostatin. Octreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.\nSandostatin is used to treat acromegaly.\nSandostatin is also used to reduce flushing episodes and watery diarrhea caused by cancerous tumors (carcinoid syndrome) or tumors called vasoactive intestinal peptide tumors (VIPomas).\n','Use Sandostatin exactly as prescribed by your doctor. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore using Sandostatin, tell your doctor if you have diabetes, gallbladder disease, heart disease, high blood pressure, a heart rhythm disorder, thyroid problems, pancreatitis, kidney disease, or liver disease.\nYou may be shown how to use an IV at home. Do not self-inject Sandostatin if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine. Be sure to follow the instructions for the exact type of Sandostatin your doctor has prescribed for you.\nTo be sure Sandostatin is helping your condition and not causing harmful effects, your blood cells, kidney function, and liver function may need to be tested often. Do not miss any follow up visits to your doctor for blood or urine tests. Call your doctor at once if you have a serious side effect such as easy bruising or bleeding, slow heart rate, or severe pain in your upper stomach spreading to your back.\nBefore using this medicine\nYou should not use Sandostatin if you are allergic to octreotide.\nTo make sure Sandostatin is safe for you, tell your doctor if you have ever had:\ndiabetes;\ngallbladder disease;\nheart disease, high blood pressure, or heart rhythm disorder;\nthyroid problems;\npancreatitis;\nliver disease; or\nkidney disease (or if you are on dialysis).\nTell your doctor if you are pregnant or breastfeeding.\nUsing Sandostatin can affect certain hormones that may make it easier for you to get pregnant, even if you were unable to get pregnant before. Talk to your doctor about using birth control to avoid unwanted pregnancy.\nSandostatin is not approved for use by anyone younger than 18 years old.\nHow should I use Sandostatin?\nUse Sandostatin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nSandostatin injection is injected under the skin, into a muscle, or as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.\nRead and carefully follow any Instructions for Use provided with your medicine.\nPrepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.\nYour healthcare provider will show you where on your body to inject Sandostatin. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nYou will need frequent medical tests.\nIf you need radiation treatment, you may need to stop using Sandostatin for a short time. Follow your doctor\'s instructions very carefully.\nStore unopened Sandostatin in the original carton in the refrigerator. Protect from light. Do not freeze.\nTake the ampul out of the refrigerator and let it reach room temperature before injecting your dose. Do not heat the ampul. Each ampul is for one use only. Throw it away after one use, even if there is still medicine left inside.\nYou may also store an unopened ampul at room temperature for up to 14 days. Throw away the ampul if not used within 14 days.\nUse a needle and syringe only once and then place them in a puncture-proof \"sharps\" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(786,'saxenda','Usual Adult Dose of Saxenda for Weight Loss:\nDose escalation should be followed to reduce the likelihood of gastrointestinal symptoms; dose escalation may be delayed by 1 additional week if necessary:\nWeek 1: Inject 0.6 mg subcutaneously once a day\nWeek 2: Inject 1.2 mg subcutaneously once a day\nWeek 3: Inject 1.8 mg subcutaneously once a day\nWeek 4: Inject 2.4 mg subcutaneously once a day\nWeek 5: Inject 3 mg subcutaneously once a day\nMaintenance dose: 3 mg subcutaneously once a day\nComments:\n-Consider dose reduction of the insulin secretagogue to reduce the risk of hypoglycemia; conversely when discontinuing use in a patient with type 2 diabetes, monitor for an increase in blood glucose.\n-If a dose of 3 mg once daily is not tolerated, discontinuation is recommended; efficacy for chronic weight management has not been established at lower doses.\n-Evaluate weight loss at 16 weeks; if at least 4% of body weight has not been lost, it is unlikely the patient will achieve and sustain clinically meaningful weight loss with continued treatment.\nUse: In adult patients with an initial BMI of 30 kg/m2 or greater (obese) or an initial BMI of 27 kg/m2 (overweight) or greater in the presence of at least 1 weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia), this drug is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management.\nBMI=Body Mass Index is calculated by dividing weight in kilograms by height in meters squared. Charts are available for determining BMI based on height and weight, including a chart in Saxenda product labeling.\n Detailed Saxenda dosage information\nWhat happens if I miss a dose?\nIf you miss your daily dose of Saxenda, use the dose as soon as you remember. Then take your next daily dose as usual on the following day. Do not take an extra dose of Saxenda or increase your dose on the following day to make up for your missed dose.\nIf you miss your dose of Saxenda for 3 days or more, call your healthcare provider to talk about how to restart your treatment.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Saxenda can slow your digestion, and it may take longer for your body to absorb any medicines you take by mouth.\nTell your doctor about all your current medicines and any you start or stop using, especially:\ninsulin; or\noral diabetes medicine - Glucotrol, Metaglip, Amaryl, Avandaryl, Duetact, DiaBeta, Micronase, Glucovance, and others.\nThis list is not complete. Other drugs may interact with liraglutide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.\n Saxenda drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Saxenda: hives; fast heartbeats; dizziness; trouble breathing or swallowing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nracing or pounding heartbeats;\nsudden changes in mood or behavior, suicidal thoughts;\nsevere ongoing nausea, vomiting, or diarrhea;\nsigns of a thyroid tumor - swelling or a lump in your neck, trouble swallowing, a hoarse voice, feeling short of breath;\ngallbladder problems - fever, upper stomach pain, clay-colored stools, jaundice (yellowing of your skin or eyes);\nsymptoms of pancreatitis - severe pain in your upper stomach spreading to your back, nausea with or without vomiting, fast heart rate;\nseverely low blood sugar - extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions); or\nkidney problems - little or no urination; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.\nCommon Saxenda side effects may include:\nnausea (especially when you start using Saxenda), vomiting, stomach pain;\nincreased heart rate;\ndiarrhea, constipation;\nheadache, dizziness; or\nfeeling tired.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Saxenda side effects (more detail)\n','Saxenda (liraglutide) is similar to a hormone that occurs naturally in the body and helps control blood sugar, insulin levels, and digestion.\nSaxenda is an injectable prescription medicine that may help some obese adults or overweight adults who also have weight-related medical problems, and children aged 12 to 17 years with a body weight above 132 pounds (60 kg) and obesity, to lose weight and keep the weight off. It is used together with diet and exercise.\nSaxenda is not for treating type 1 or type 2 diabetes. Saxenda is not a weight-loss medicine or appetite suppressant.\n','The Victoza brand of liraglutide is used together with diet and exercise to treat type 2 diabetes. Do not use Saxenda and Victoza together.\nYou should not use Saxenda if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer, insulin-dependent diabetes, diabetic ketoacidosis, or are pregnant.\nIn animal studies, liraglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses.\nCall your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.\nBefore using Saxenda\nYou should not use Saxenda if you are allergic to liraglutide, or if you have:\nmultiple endocrine neoplasia type 2 (tumors in your glands);\na personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or\ndiabetic ketoacidosis (call your doctor for treatment).\nYou should not use Saxenda if you also use insulin or other medicines like liraglutide (albiglutide, dulaglutide, exenatide, Byetta, Bydureon, Tanzeum, Trulicity).\nTo make sure Saxenda is safe for you, tell your doctor if you have:\nstomach problems causing slow digestion;\nkidney or liver disease;\nhigh triglycerides (a type of fat in the blood);\nheart problems;\na history of problems with your pancreas or gallbladder; or\na history of depression or suicidal thoughts.\nIn animal studies, liraglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.\nIt is not known whether Saxenda will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.\nIt is not known whether liraglutide passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.\nSaxenda is not FDA-approved for use by anyone younger than 18 years old.\nHow should I use Saxenda?\nSaxenda is usually given once per day. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.\nDo not use Saxenda and Victoza together. These two brands contain the same active ingredient but they should not be used together.\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\nSaxenda is injected under the skin at any time of the day, with or without a meal. You will be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes.\nSaxenda comes in a prefilled injection pen. Ask your pharmacist which type of needles are best to use with your pen.\nYour care provider will show you the best places on your body to inject Saxenda. Use a different place each time you give an injection. Do not inject into the same place two times in a row.\nDo not use Saxenda if it has changed colors or if it has particles in it. Call your pharmacist for new medicine.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination, blurred vision, headache, and tiredness.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nUse a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof \"sharps\" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.\nSaxenda is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStoring unopened injection pens: Store in the refrigerator. Do not freeze Saxenda, and throw away the medication if it has become frozen. Do not use an unopened injection pen if the expiration date on the label has passed.\nStoring after your first use: You may keep \"in-use\" injection pens in the refrigerator or at room temperature. Protect the pens from moisture, heat, and sunlight. Use within 30 days. Remove the needle before storing an injection pen, and keep the cap on the pen when not in use.\n','Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.\nDo not use Saxenda together with other weight loss products, diet pills, or appetite suppressants.\n'),(787,'scopolamine','Administration\nAdminister orally or by IM, direct IV, or sub-Q injection; also may administer percutaneously by topical application of a transdermal system (Transderm Scop).\nWhen administered orally or IM for the prevention of motion sickness, generally administer 1 hour (range: 0.5–1.5 hours) before anticipated exposure to motion.\nWhen used preoperatively, administer 30–60 minutes prior to the anticipated time of induction of anesthesia or at the same time other preanesthetic medications (e.g., opiates, sedatives) are administered, since scopolamine may cause behavioral changes in patients with pain or anxiety. (See CNS Effects under Cautions.)\nTransdermal Administration\nTo prevent motion sickness, apply at least 4 hours (e.g., 4–24 hours) before anticipated exposure to motion.\nTo prevent postoperative nausea and vomiting, apply the evening before scheduled surgery. \nFor use in cesarean section, apply 1 hour prior to surgery to minimize exposure of the fetus to the drug. \nTransdermal system should not be cut; only one transdermal system should be worn at any time.\nPrior to administration, wipe area behind the ear with a clean, dry tissue to ensure it is dry.\nTo expose adhesive surface, peel and discard the clear plastic protective strip prior to administration; avoid finger contact with exposed adhesive layer to prevent contamination of the fingers with scopolamine.\nApply to dry, hairless area of skin behind the ear (postauricular) by firmly pressing the system with the adhesive side touching the skin.\nIf the system becomes dislodged during the intended period of use (up to 72 hours), remove it and replace with another system at a different postauricular site.\nGenerally not affected by limited exposure to water (e.g., during bathing or swimming).\nDosage\nTablets and injection: Available as scopolamine hydrobromide; dosage expressed in terms of the salt.\nPediatric Patients\nUsual Dosage\nIM, IV, Sub-Q\nChildren 6 month to 3 years of age: 0.1–0.15 mg\nChildren 3–6 years of age: 0.2–0.3 mg\nMotion Sickness\nSub-Q\nUsually 0.006 mg/kg (6 mcg/kg).\nPostoperative Nausea and Vomiting\nSub-Q\nUsually 0.006 mg/kg (6 mcg/kg).\nAdults\nUsual Dosage\nOral\n0.4–0.8 mg.\nIM, IV, Sub-Q\n0.32–0.65 mg; may be repeated 3 or 4 times daily if necessary.\nMotion Sickness\nOral\nInitially, 0.25–0.8 mg 1 hour before exposure to motion; subsequently, 0.25–0.8 mg 3 times daily as needed and tolerated.\nIM, IV, Sub-Q\nUsually 0.32–0.65 mg; may be repeated 3 or 4 times daily if necessary.\nAlternatively, 0.2–1 mg.\nTransdermal\nUsually, one scopolamine system applied ≥4 hours prior to anticipated exposure to motion.\nMay use for up to 72 hours if necessary or may remove during the 72-hour period when an antiemetic effect is no longer required.\nWhen necessary to continue beyond 72 hours, remove the initially applied system and place another system behind the ear at a different site.\nPostoperative Nausea and Vomiting\nTransdermal\nApply one transdermal system the evening before scheduled surgery. \nFor cesarean section, apply 1 hour prior to surgery to minimize exposure of the infant to the drug. \nAllow patch to remain in place for 24 hours following surgery, then remove and discard. \nSurgery\nObstetric Anmesia or Preoperative Sedation\nUsually 0.32–0.65 mg.\nInhibition of Salivation\nUsually 0.32–0.65 mg. Alternatively, 0.2–0.6 mg has been suggested.\nAmnestic Effect\nUsually 0.32–0.65 mg.\nSedative or Tranquilizing Effect\nUsually 0.6 mg.\n Detailed Scopolamine dosage information\n','Orally Administered Drugs\nPotential pharmacokinetic interaction (altered GI absorption of various drugs): Antimuscarinics may inhibit GI motility, delay gastric emptying, and prolong GI transit time. \nSpecific Drugs\nDrug\nInteraction\nComments\nAmantadine\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nAntacids\nPossible decreased absorption of antimuscarinic \nAdminister oral scopolamine at least 1 hour before antacids\nAntiarrhythmic agents (quinidine, disopyramide, procainamide)\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nAntidepressants, tricyclic\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nAntihistamine agents (meclizine)\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nAntiparkinsonian agents\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nBelladonna alkaloids\nPossible additive anticholinergic effects \nUse concomitantly with extra caution \nCorticosteroids\nPossible increased intraocular pressure\nCNS depressants (e.g., sedatives, tranquilizers, alcohol)\nPossible increased CNS depressive effects   (see CNS Effects under Cautions.)\nUse concomitantly with caution   \nGlutethimide\nPossible additive anticholinergic adverse effects\nUse concomitantly with caution \nKetoconazole\nPossible decreased ketoconazole absorption\nIf concomitant therapy is necessary, give antimuscarinic at least 2 hours after ketoconazole\nLevodopa\nPossible increased gastric metabolism of levodopa and decreased levodopa absorption in the small intestine\nToxicity may result from increased levodopa absorption if antimuscarinic is discontinued without a concomitant reduction in levodopa dosage\nMeperidine\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nPhenothiazines\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \nPotassium chloride\nAntimuscarinics may potentiate potassium chloride\'s local GI mucosal effects\nUse antimuscarinics cautiously with potassium chloride preparations (especially wax-matrix preparations), monitor carefully for evidence of GI mucosal lesions\nSkeletal muscle relaxants\nPossible additive anticholinergic adverse effects \nUse concomitantly with caution \n Scopolamine drug interactions (more detail)\n',NULL,'Motion Sickness\nPrevention of motion-induced nausea and vomiting; considered most effective drug for this use.\nOral or IM administration usually reserved for patients exposed to short periods of intense motion or those highly susceptible to motion because these routes have short duration of effect and high incidence of adverse effects.\nTransdermal administration is effective and has fewer adverse effects and increased duration compared with oral administration.\nPostoperative Nausea and Vomiting\nUsed transdermally for prevention of nausea and vomiting associated with recovery from anesthesia and surgery, but efficacy is equivocal.     \nSurgery\nHas been used preoperatively to inhibit salivation and excessive respiratory tract secretions, but use of general anesthetics (e.g., thiopental [no longer commercially available in the US], halothane) that do not stimulate secretions has reduced the need for this use.\nUsed preoperatively and in obstetrics in conjunction with analgesics or sedatives to produce tranquilization and amnesia; however, benzodiazepines may be preferred.\nHas greater sedative, antisecretory (e.g., on respiratory secretions), and antiemetic effects than atropine; however, less effective than atropine in preventing intraoperative cholinergic effects (e.g., cardiac arrhythmias, hypotension, bradycardia).\nParkinsonian Syndrome\nHas been used for symptomatic treatment of parkinsonian syndrome; however, antimuscarinincs generally have been replaced with dopaminergic drugs.\n',NULL,NULL),(788,'semaglutide','Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nRybelsus (oral) is taken by mouth when you first wake up, at least 30 minutes before you eat or drink anything. Take this medicine with no more than 4 ounces of water. Swallow the tablet whole and do not crush, chew, or break it.\nEat within 30 to 60 minutes after taking Rybelsus.\nOzempic (injection) is injected under the skin.\nRead and follow all Instructions for Use. Ask your doctor or pharmacist if you need help.\nPrepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.\nOzempic is usually given once per week at any time of the day, with or without a meal. If you want to change your weekly injection day, wait at least 2 days after your most recent injection before giving another one.\nYour healthcare provider will show you where to inject Ozempic. Do not inject into the same place two times in a row.\nBlood sugar can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals.\nLow blood sugar (hypoglycemia) can make you feel very hungry, dizzy, irritable, or shaky. To quickly treat hypoglycemia, eat or drink hard candy, crackers, raisins, fruit juice, or non-diet soda. Your doctor may prescribe glucagon injection in case of severe hypoglycemia.\nTell your doctor if you have frequent symptoms of high blood sugar (hyperglycemia) such as increased thirst or urination. Ask your doctor before changing your medication dosage.\nCall your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking semaglutide. This can lead to kidney failure.\nYour treatment may also include diet, exercise, weight control, and special medical care.\nStore Rybelsus tablets in their original package at room temperature, away from moisture and heat.\nStoring unopened Ozempic injection pens: Store in the refrigerator. Do not freeze semaglutide, and throw away the medication if it has become frozen. Do not use an unopened injection pen if the expiration date on the label has passed.\nStoring after your first use: You may keep an \"in-use\" injection pen in the refrigerator or at room temperature. Protect the pen from heat and sunlight. Remove the needle before storing an injection pen, and keep the cap on the pen when not in use. Throw the injection pen away 56 days after the first use.\nDo not reuse a needle or injection pen. Place them in a puncture-proof \"sharps\" container and dispose of it following state or local laws. Keep out of the reach of children and pets.\n Detailed Semaglutide dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nFor Rybelsus: Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nFor Ozempic: Use the medicine as soon as you can, but skip the missed dose if you are more than 5 days late for the dose. Do not use two doses within 5 days of each other.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Semaglutide can slow your digestion, and it may take longer for your body to absorb any medicines you take by mouth.\nTell your doctor about all your other medicines, especially insulin or other diabetes medicine.\nOther drugs may affect semaglutide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Semaglutide drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives, itching; dizziness, fast heartbeats; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nvision changes;\nsigns of a thyroid tumor--swelling or a lump in your neck, trouble swallowing, a hoarse voice, feeling short of breath;\nsymptoms of pancreatitis--severe pain in your upper stomach spreading to your back, nausea with or without vomiting, fast heart rate;\nlow blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or\nkidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath.\nCommon side effects may include:\nnausea, vomiting, stomach pain, loss of appetite;\ndiarrhea; or\nconstipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Semaglutide side effects (more detail)\n','Semaglutide is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus (not for type 1 diabetes).\nSemaglutide may also be used for purposes not listed in this medication guide.\n','You should not use semaglutide if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer, insulin-dependent diabetes, or diabetic ketoacidosis.\nCall your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.\nBefore taking this medicine\nYou should not use semaglutide if you are allergic to it, or if you have:\nmultiple endocrine neoplasia type 2 (tumors in your glands);\na personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or\ndiabetic ketoacidosis (call your doctor for treatment).\nTell your doctor if you have ever had:\na stomach or intestinal disorder;\npancreatitis;\nkidney disease; or\neye problems caused by diabetes (retinopathy).\nIn animal studies, semaglutide caused thyroid tumors or thyroid cancer. It is not known whether these effects would occur in people using regular doses. Ask your doctor about your risk.\nSemaglutide may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Semaglutide can have long-lasting effects on your body. Avoid getting pregnant for at least 2 months after you stop using  semaglutide.\nYou should not breastfeed while using semaglutide.\nSemaglutide is not approved for use by anyone younger than 18 years old.\n','Never share an injection pen, even if you changed the needle. Sharing this device can pass infection or disease from person to person.\n'),(789,'senna','When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.\nIf you choose to use senna, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.\nYou must chew the chewable tablet before you swallow it.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nSenna should produce a bowel movement within 6 to 12 hours after you take it.\nDo not use different formulations (such as tablets and liquid) at the same time without medical advice. Using different formulations together increases the risk of an overdose of senna.\nSenna may be unsafe when taken long-term or in high doses. Using this medicine for longer than 2 weeks may cause your bowels to stop functioning normally. Long-term use may also cause a serious electrolyte imbalance. Certain electrolyte imbalances can cause muscle weakness, heart problems, liver damage, and other harmful effects.\nCall your healthcare provider if your constipation does not improve after 1 week of use, or if your constipation gets worse.\nStore at room temperature away from moisture, heat, and light.\n Detailed Senna dosage information\nWhat happens if I miss a dose?\nSkip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Do not take senna without medical advice if you are using any of the following medications:\nbirth control pills or hormone replacement therapy;\ndigoxin (Lanoxin);\na diuretic (water pill); or\nwarfarin (Coumadin, Jantoven).\nThis list is not complete. Other drugs may interact with senna, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Senna drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to senna: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using senna and call your doctor at once if you have:\nrectal bleeding;\nno bowel movement within 12 hours after using senna; or\nlow potassium level - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nConstipation is the most common side effect of senna. Less serious side effects may be more likely, and you may have none at all.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Senna side effects (more detail)\n','Senna is also known as Cassia, Fan Xie Ye, Alejandrina, Séné, Sennae, and Tinnevelly.\nSenna is likely effective in alternative medicine as an aid in treating occasional constipation in adults and children at least 2 years old. It is sometimes used together with another laxative or stool softener such as lactulose, psyllium, docusate, or mineral oil.\nSenna is possibly effective as a bowel preparation before colonoscopy.\nOther uses not proven with research include weight loss, irritable bowel syndrome, hemorrhoids, anal fissures (tears in the lining of the anus), or after anal or rectal surgery.\nIt is not certain whether senna is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Senna should not be used in place of medication prescribed for you by your doctor.\nSenna is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.\n','Not all uses for senna have been approved by the FDA. Senna should not be used in place of medication prescribed for you by your doctor.\nSenna is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.\nUse senna as directed on the label, or as your healthcare provider has prescribed. Do not use this product in larger amounts or for longer than recommended.\nCall your healthcare provider if your symptoms do not improve, or if they get worse while using senna. Do not use this product for longer than 1 week without the advice of a healthcare provider.\nBefore taking this medicine\nYou should not use senna if you are allergic to it, or if you have:\ndiarrhea or loose stools;\nsevere stomach pain;\nswelling or a blockage in your digestive tract (stomach or intestines);\nCrohn\'s disease, ulcerative colitis, appendicitis;\nhemorrhoids, anal prolapse; or\nif you are dehydrated.\nAsk a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have ever had:\nan electrolyte imbalance (such as low levels of potassium in your blood);\nany change in bowel habits that has lasted longer than 2 weeks;\nlong-term bowel problems;\nheart disease; or\nstomach pain, nausea, or vomiting.\nAsk a doctor before using senna if you are pregnant or breastfeeding.\nSome forms of senna are made for use by children. Do not give any herbal/health supplement to a child without the advice of a doctor.\n','Follow your healthcare provider\'s instructions about any restrictions on food, beverages, or activity.\n'),(790,'senokot','When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.\nIf you choose to use senna, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.\nYou must chew the chewable tablet before you swallow it.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nSenna should produce a bowel movement within 6 to 12 hours after you take it.\nDo not use different formulations of senna (such as tablets and liquid) at the same time without medical advice. Using different formulations together increases the risk of an overdose of senna.\nSenna may be unsafe when taken long-term or in high doses. Using senna for longer than 2 weeks may cause your bowels to stop functioning normally. Long-term use may also cause a serious electrolyte imbalance. Certain electrolyte imbalances can cause muscle weakness, heart problems, liver damage, and other harmful effects.\nCall your healthcare provider if your constipation does not improve after 1 week of using senna, or if constipation gets worse.\nStore at room temperature away from moisture, heat, and light.\n Detailed Senokot dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nSkip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Do not take senna without medical advice if you are using any of the following medications:\nbirth control pills or hormone replacement therapy;\ndigoxin (Lanoxin);\na diuretic (water pill); or\nwarfarin (Coumadin, Jantoven).\nThis list is not complete. Other drugs may affect senna, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Senokot drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using senna and call your doctor at once if you have:\nrectal bleeding;\nno bowel movement within 12 hours after using senna; or\nlow potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.\nConstipation is the most common side effect of senna. Less serious side effects may be more likely, and you may have none at all.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Senokot side effects (more detail)\n','Senna is also known as Cassia, Fan Xie Ye, Alejandrina, Séné, Sennae, and Tinnevelly.\nSenna is likely effective in alternative medicine as an aid in treating occasional constipation in adults and children at least 2 years old. Senna is sometimes used together with another laxative or stool softener such as lactulose, psyllium, docusate, or mineral oil.\nSenna is possibly effective as a bowel preparation before colonoscopy.\nOther uses not proven with research include weight loss, irritable bowel syndrome, hemorrhoids, anal fissures (tears in the lining of the anus), or after anal or rectal surgery.\nIt is not certain whether senna is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Senna should not be used in place of medication prescribed for you by your doctor.\nSenna is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.\nSenna may also be used for purposes not listed in this product guide.\n','Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use senna if you are allergic to it, or if you have:\ndiarrhea or loose stools;\nsevere stomach pain;\nswelling or a blockage in your digestive tract (stomach or intestines);\nCrohn\'s disease, ulcerative colitis, appendicitis;\nhemorrhoids, anal prolapse; or\nif you are dehydrated.\nAsk a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have ever had:\nan electrolyte imbalance (such as low levels of potassium in your blood);\nany change in bowel habits that has lasted longer than 2 weeks;\nlong-term bowel problems;\nheart disease; or\nstomach pain, nausea, or vomiting.\nAsk a doctor before using this medicine if you are pregnant or breastfeeding.\nSome forms of senna are made for use by children. Do not give any herbal/health supplement to a child without the advice of a doctor.\n','Follow your healthcare provider\'s instructions about any restrictions on food, beverages, or activity.\n'),(791,'sernivo','Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.\nDo not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Rinse with water if this medicine gets in your eyes or mouth.\nRead and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.\nWash your hands before and after using this medicine, unless you are using the medicine to treat the skin on your hands.\nApply a small amount to the affected area and rub it gently into the skin. Do not apply Sernivo over a large area of skin.\nDo not cover the treated skin area unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.\nUse Sernivo regularly to get the most benefit. Stop using the medicine once your symptoms clear up.\nCall your doctor if your skin condition does not improve after 2 weeks, or if it gets worse.\nDo not use Diprolene for longer than 2 weeks in a row. Do not use Sernivo or Luxiq for longer than 4 weeks.\nStore at room temperature away from moisture and heat.\nThe foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.\n Detailed Sernivo dosage information\nWhat happens if I miss a dose?\nApply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.\nLong term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.\n','Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.\n Sernivo drug interactions (more detail)\nDoes Sernivo interact with my other drugs?\nEnter other medications to view a detailed report.\nDrug name\nAdd a drug to check interactions\nAdd\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nStop using betamethasone and call your doctor at once if you have:\nsevere skin irritation where the medicine was applied; or\nsigns of skin infection (swelling, redness, warmth, oozing).\nYour skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using betamethasone and call your doctor if you have:\nblurred vision, tunnel vision, eye pain, or seeing halos around lights;\nslow wound healing, thinning skin, increased body hair;\nincreased thirst or urination, dry mouth, fruity breath odor;\nweight gain, puffiness in your face; or\nmuscle weakness, tired feeling, depression, anxiety, feeling irritable.\nSteroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.\nCommon side effects may include:\nitching, redness, burning, stinging, or blistering of treated skin;\nskin bruising or shiny appearance; or\nfolliculitis (redness or crusting around your hair follicles).\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sernivo side effects (more detail)\n','Betamethasone is a highly potent steroid that prevents the release of substances in the body that cause inflammation.\nSernivo (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.\nSernivo may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use Sernivo if you are allergic to it.\nTell your doctor if you have ever had:\nskin irritation after using steroid medicine;\nthinning of the skin where you will apply  Sernivo;\ncataracts or glaucoma;\ndiabetes;\nliver disease;\nadrenal gland problems; or\nany type of skin infection.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.\nIt may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks. If you apply betamethasone to your chest, avoid areas that may come into contact with the baby\'s mouth.\nDo not use Sernivo on a child without a doctor\'s advice. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.\nDiprolene is not approved for use by anyone younger than 13 years old. Sernivo and Luxiq are not approved for anyone younger than 18 years old.\n','Do not get  Sernivo in your eyes. If contact does occur, rinse with water.\nAvoid applying Sernivo to the skin of your face, underarms, or groin area without your doctor\'s instruction.\nDo not use Sernivo to treat any condition that has not been checked by your doctor.\n'),(792,'seroquel','Never take Seroquel in larger amounts, or for longer than recommended by your doctor. Follow all directions on your prescription label. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include tremors or other uncontrollable muscle movements.\nTake this medicine with a full glass of water. You may take immediate-release Seroquel with or without food. It is suggested that Seroquel XR be administered without food or with a light meal (< 300 calories), preferably in the evening.\nDo not crush, chew, or break an extended-release tablet. Swallow it whole.\nSeroquel may cause you to have high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis while you are taking Seroquel.\nYou should not stop using Seroquel suddenly. Stopping suddenly may make your condition worse.\nBlood pressure may need to be checked often in a child or teenager taking Seroquel.\nQuetiapine can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking Seroquel.\nStore at room temperature away from moisture and heat.\n Detailed Seroquel dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of quetiapine can be fatal.\n','Seroquel can cause a serious heart problem if you use certain medicines at the same time, including certain antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Seroquel.\nTaking Seroquel with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.\nMany drugs can interact with quetiapine. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:\nantibiotic or antifungal medicines;\nantiviral medicine to treat hepatitis or HIV/AIDS;\nheart or blood pressure medicines;\nmedicine to treat mental illness;\nSt. John\'s wort;\nseizure medicine; or\nmedicines used to treat tuberculosis.\nThis list is not complete and many other drugs can interact with quetiapine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.\n Seroquel drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Seroquel: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\nmask-like appearance of the face, trouble swallowing, problems with speech;\na light-headed feeling, like you might pass out;\nblurred vision, tunnel vision, eye pain, or seeing halos around lights;\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, fainting;\nhigh blood sugar - increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or\nlow blood cell counts - sudden weakness or ill feeling, fever, chills, cold or flu symptoms, cough, sore throat, red or swollen gums, painful mouth sores, skin sores, trouble breathing.\nCommon Seroquel side effects may include:\nspeech problems;\ndizziness, drowsiness, tiredness;\nlack of energy;\nfast heartbeats;\nstuffy nose;\nincreased appetite, weight gain;\nupset stomach, vomiting, constipation;\ndry mouth; or\nproblems moving.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Seroquel side effects (more detail)\n','Seroquel (quetiapine) is an antipsychotic medicine. It works by changing the actions of chemicals in the brain.\nSeroquel is used to treat schizophrenia in adults and children who are at least 13 years old.\nSeroquel is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.\nSeroquel is also used together with antidepressant medications to treat major depressive disorder in adults.\nSeroquel may also be used for purposes not listed in this medication guide.\n','Never take Seroquel in larger amounts, or for longer than recommended by your doctor. High doses or long-term use can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include tremors or other uncontrollable muscle movements.\nStop using Seroquel and call your doctor at once if you have the following symptoms: very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, uncontrolled muscle movements, feeling light-headed, blurred vision, eye pain, increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting.\nSome young people have thoughts about suicide when first taking Seroquel. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nSeroquel is not FDA approved for use in psychotic conditions related to dementia. Quetiapine may increase the risk of death in older adults with dementia-related psychosis.\nBefore taking this medicine\nYou should not use Seroquel if you are allergic to quetiapine.\nSeroquel may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.\nTo make sure Seroquel is safe for you, tell your doctor if you have:\nliver or kidney disease;\nheart disease, heart rhythm problems, a history of heart attack or stroke;\nhigh or low blood pressure;\na history of low white blood cell (WBC) counts;\nabnormal thyroid tests or prolactin levels;\nseizures or epilepsy;\ncataracts;\nhigh cholesterol or triglycerides;\na personal or family history of diabetes; or\ntrouble swallowing.\nSome young people have thoughts about suicide when first taking Seroquel. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nTaking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking Seroquel, do not stop taking it without your doctor\'s advice.\nThis medicine may temporarily affect fertility (your ability to have children) in women.\nSeroquel can pass into breast milk and may harm a nursing baby. You should not breastfeed while you are using Seroquel unless directed by a doctor.\nDo not give Seroquel to a child without a doctor\'s advice. Extended-release Seroquel XR is for use only in adults and should not be given to anyone younger than 18 years old.\n','Avoid drinking alcohol. Dangerous side effects could occur.\nSeroquel may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.\nAvoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries.\nAvoid becoming overheated or dehydrated during exercise and in hot weather. You may be more prone to heat stroke.\n'),(793,'sertraline','Usual Adult Dose for Depression:\nInitial dose: 50 mg orally once a day\nMaintenance Dose: 50 to 200 mg orally once a day.\nUsual Adult Dose for Obsessive Compulsive Disorder:\nInitial dose: 50 mg orally once a day\nMaintenance Dose: 50 to 200 mg orally once a day\nUsual Adult Dose for Panic Disorder:\nInitial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day\nMaintenance dose: 50 to 200 mg orally once a day.\nUsual Adult Dose for Post Traumatic Stress Disorder:\nInitial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day\nMaintenance dose: 50 to 200 mg orally once a day\nUsual Adult Dose for Social Anxiety Disorder:\nInitial dose: 25 mg orally once a day, increased after one week to 50 mg orally once a day\nMaintenance dose: 50 to 200 mg orally once a day.\nUsual Adult Dose for Premenstrual Dysphoric Disorder:\nContinuous regimen:\n-Initial dose: 50 mg orally once a day during the menstrual cycle\n-Maintenance dose: 50 to 150 mg orally once a day during the menstrual cycle\nCyclic regimen:\n-Initial dose: 50 mg orally once a day starting 14 days prior to the anticipated start of menstruation through to the first full day of menses, and repeated with each new cycle\n-Maintenance dose: 50 to 100 mg orally once a day.\nUsual Pediatric Dose for Obsessive Compulsive Disorder:\n6 to 12 years:\n-Initial dose: 25 mg orally once a day\n-Maintenance dose: 25 to 200 mg orally once a day\n13 to 17 years:\n-Initial dose: 50 mg orally once a day\n-Maintenance dose: 50 to 200 mg orally once a day.\n Detailed Sertraline dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Sertraline can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.\nAsk your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with sertraline may cause you to bruise or bleed easily.\nOther drugs may interact with sertraline, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Sertraline drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to sertraline: skin rash or hives (with or without fever or joint pain); difficulty breathing; swelling of your face, lips, tongue, or throat.\nReport any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.\nCall your doctor at once if you have:\na seizure;\nvision changes, eye pain, redness, or swelling;\nlow blood sodium - headache, confusion, problems with thinking or memory, weakness, feeling unsteady; or\nmanic episodes - racing thoughts, increased energy, unusual risk-taking behavior, extreme happiness, being irritable or talkative.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nSertraline can affect growth in children. Your child\'s height and weight may be checked often.\nCommon sertraline side effects may include:\nindigestion, nausea, diarrhea, loss of appetite;\nsweating;\ntremors; or\nsexual problems.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sertraline side effects (more detail)\n','Sertraline is an antidepressant in a group of drugs called . Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.\nSertraline is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD).\nSertraline is also used to treat premenstrual dysphoric disorder.\n','You should not use sertraline if you also take pimozide, or if you are being treated with methylene blue injection.\nDo not use sertraline if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.\nSome children and young adults have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.\nSeek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.\nBefore taking this medicine\nYou should not use sertraline if you are allergic to it, or if you also take pimozide. Do not use the liquid form of this medicine if you take disulfiram (Antabuse).\nDo not use sertraline within 14 days before or 14 days after using an MAO inhibitor. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.\nTell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson\'s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with sertraline could cause a serious condition called serotonin syndrome.\nTo make sure sertraline is safe for you, tell your doctor if you have ever had:\nbipolar disorder (manic depression);\nheart disease, high blood pressure, or a stroke;\nliver or kidney disease;\nseizures;\nglaucoma;\nbleeding problems, or if you take warfarin (Coumadin, Jantoven);\nlong QT syndrome; or\nlow levels of sodium in your blood.\nSome young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.\nSertraline is approved for use in children at least 6 years old, only to treat obsessive-compulsive disorder but not depression.\nTaking sertraline during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop this medicine without asking your doctor.\nAsk a doctor if it is safe to breastfeed while using this medicine.\nHow should I take sertraline?\nTake sertraline exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nTake sertraline with or without food, at the same time each day.\nSertraline liquid (oral concentrate) must be diluted with a liquid right before you take it. Read and carefully follow all mixing instructions provided with your medicine. Ask your doctor or pharmacist if you need help.\nMeasure the mixed medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).\nSertraline may cause false results on a drug-screening urine test. Tell the laboratory staff that you use this medicine.\nDo not stop using sertraline suddenly, or you could have unpleasant symptoms (such as agitation, confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine.\nStore tightly closed at room temperature, away from moisture and heat.\n','Drinking alcohol with sertraline can cause side effects.\nAvoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.\n'),(794,'sevelamer','Usual Adult Dose for Hyperphosphatemia of Renal Failure:\nInitial Dosing for patients not on a phosphate binder: 800 mg to 1600 mg orally 3 times a day with mealsBased on serum phosphorus level: -Phosphorus greater than 5.5 to less than 7.5 mg/dL: 800 mg 3 times a day with meals-Phosphorus greater than or equal to 7.5 mg/dL: 1600 mg 3 times a day with meals-Titrate in increments of 800 mg 3 times a day at 2-week intervals with the goal of controlling serum phosphorus within target range.Average prescribed dose: 7.2 g/day (2.4 g with each meal)Maximum studied dose: 14 g per day (carbonate); 13 g per day (hydrochloride)Switching from the hydrochloride salt to carbonate: Use the same dose, however further titration may be necessary to achieve desired phosphorus levels.  Switching from calcium acetate: Substitute approximately mg for mg Comment: Treatment of hyperphosphatemia includes reduction in dietary intake of phosphate, inhibition of intestinal phosphate absorption with phosphate binders, and removal of phosphate with dialysis.  Use: To control serum phosphorus levels in patients with chronic kidney disease on dialysis.\n Detailed Sevelamer dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Other drugs may interact with sevelamer, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.\n Sevelamer drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nStop using sevelamer and call your doctor at once if you have:\nchoking, or trouble swallowing;\nblack, bloody, or tarry stools;\nsevere constipation with stomach pain; or\nconstipation that gets worse or does not clear up.\nCommon side effects may include:\nnausea, vomiting, stomach pain, loss of appetite;\nupset stomach, gas, bloating;\ndiarrhea, constipation;\ntired feeling;\nitching; or\njoint pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sevelamer side effects (more detail)\n','Sevelamer is a phosphate binder. Sevelamer helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus.\nSevelamer is used to control phosphorus levels in people with chronic kidney disease who are on dialysis.\nSevelamer may also be used for purposes not listed in this medication guide.\n','You should not take  sevelamer if you have a bowel obstruction.\nBefore taking this medicine\nYou should not take sevelamer if you are allergic to it, or if you have a bowel obstruction.\nTo make sure sevelamer is safe for you, tell your doctor if you have:\ntrouble swallowing;\nsevere constipation;\na blockage in your intestines;\nslow digestion;\na stomach or intestinal disorder; or\nif you have recently had stomach or intestinal surgery.\nIt is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Your dose needs may be different during pregnancy.\nTaking sevelamer while you are pregnant can lower your blood levels of certain vitamins or folic acid. Follow your doctor\'s instructions about taking vitamins or mineral supplements during pregnancy.\nBecause sevelamer is not absorbed into the bloodstream, it is not expected to be harmful to a nursing baby.\nSevelamer is not approved for use by anyone younger than 6 years old.\nHow should I take sevelamer?\nFollow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use  sevelamer in larger or smaller amounts or for longer than recommended.\nTake sevelamer with meals.\nSevelamer powder must be dissolved in water before you take it. The 0.8-gram packet should be mixed with at least 1 ounce (2 tablespoons) of water. The 2.4-gram packet should be mixed with at least 2 ounces (4 tablespoons) of water.\nStir the powder in water until it is completely dissolved. Stir and drink this mixture right away. To get the entire dose, add a little more water to the same glass, swirl gently and drink right away.\nWhile using sevelamer, you may need frequent blood tests.\nCall your doctor if you have have trouble swallowing the tablet, or if it feels like it gets stuck in your esophagus after you swallow it.\nSevelamer may be only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must eat or avoid to help control your condition.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Be sure to take the missed dose with food. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','You may be taking other medicines that should not be taken at the same time. Taking sevelamer can make it harder for your body to absorb certain drugs, making them less effective:\nciprofloxacin (Cipro) should be taken at least 2 hours before or 6 hours after you take sevelamer;\nmycophenolate mofetil (CellCept) should be taken at least 2 hours before you take sevelamer.\n'),(795,'shingrix','Usual Adult Dose for Varicella-Zoster -- Prophylaxis:\n0.5 mL intramuscularly\n-Administer two doses, with the second dose given 2 to 6 months after the first dose\nComments:\n-This drug is not indicated for prevention of primary varicella infection (chickenpox).\nUse: Prevention of herpes zoster (shingles) in adults aged 50 years and older\n Detailed Shingrix dosage information\nWhat happens if I miss a dose?\nCall your doctor if you miss the second dose or if you get behind schedule. You must receive all recommended doses of Shingrix to be fully protected against disease.\nWhat happens if I overdose?\nAn overdose of Shingrix is unlikely to occur.\n','Other drugs may affect zoster vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Shingrix drug interactions (more detail)\n','You should not receive the second shot if you had a life-threatening allergic reaction after the first shot.\nKeep track of any and all side effects you have after receiving zoster vaccine. When you receive the second shot, tell the doctor if the first shot caused any side effects.\nBecoming infected with shingles is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.\nGet emergency medical help if you have signs of an allergic reaction to Shingrix: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have a high fever.\nCommon Shingrix side effects include:\nheadache, muscle pain;\nfeeling tired;\nstomach pain, nausea, vomiting, diarrhea;\nfever, shivering; or\npain, redness, or swelling where the shot was given.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.\n Shingrix side effects (more detail)\n','Shingrix is a vaccine used for the prevention of herpes zoster. Herpes zoster is caused by the same virus (varicella) that causes chickenpox in children. When this virus becomes active again, it can cause herpes zoster, or shingles. Shingrix helps prevent shingles.\nShingrix works by exposing you to a small dose of inactive virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.\nShingrix is used to prevent herpes zoster virus (shingles) in people age 50 and older, including people who previously received a live zoster vaccine (Zostavax).\nShingrix will not treat chickenpox, shingles, or nerve pain caused by shingles (post-herpetic neuralgia).\n','You should not receive Shingrix if you have ever had a life-threatening allergic reaction to any vaccine containing zoster virus.\nYou should not receive the second shot if you had a life-threatening allergic reaction after the first shot.\nTo make sure this vaccine is safe for you, tell your doctor if you have ever had an allergic reaction to any vaccine.\nBefore taking this medicine\nYou should not receive Shingrix if you have ever had a life-threatening allergic reaction to inactivated zoster virus vaccine.\nTell your doctor if you have ever had an allergic reaction to any vaccine.\nIt is not known whether zoster vaccine will harm an unborn baby. Tell your doctor if you are pregnant.\nIt may not be safe to breast-feed a baby shortly after you receive Shingrix. Ask your doctor about any risks.\nHow is Shingrix given?\nShingrix is given as an injection (shot) into a muscle. A healthcare provider will give you this injection.\nShingrix is usually given in a series of 2 shots. The second shot may be given any time within 2 to 6 months after the first shot.\nYou may receive Shingrix at the same time that you get a flu shot.\nRead all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),(796,'sildenafil','Take sildenafil exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nRevatio is usually taken three times each day, about 4 to 6 hours apart.\nViagra is usually taken only when needed, 30 minutes to 1 hour before sexual activity. You may take it up to 4 hours before sexual activity. Do not take Viagra more than once per day.\nShake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nViagra can help you have an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor\'s instructions.\nDuring sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of sildenafil.\nStore at room temperature away from moisture and heat.\n Detailed Sildenafil dosage information\nWhat happens if I miss a dose?\nSince Viagra is used as needed, you are not likely to miss a dose.\nIf you miss a dose of Revatio, take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Do not take sildenafil with similar medications such as avanafil (Stendra), tadalafil (Cialis) or vardenafil (Levitra). Tell your doctor about all other medications you use for erectile dysfunction.\nDo not take sildenafil if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).\nDo not take sildenafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (\"poppers\"). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.\nIn addition, tell your doctor about all your other medicines, especially:\ndrugs to treat high blood pressure or a prostate disorder;\nantifungal medicine - ketoconazole or itraconazole; or\nmedicine to treat HIV/AIDS - ritonavir and others.\nThis list is not complete. Other drugs may interact with sildenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.\n Sildenafil drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to sildenafil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nStop taking sildenafil and get emergency medical help if you have:\nheart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;\nvision changes or sudden vision loss;\nerection is painful or lasts longer than 4 hours (prolonged erection can damage the penis);\nringing in your ears, or sudden hearing loss;\nirregular heartbeat;\nswelling in your hands, ankles, or feet;\nshortness of breath;\nseizure (convulsions); or\na light-headed feeling, like you might pass out.\nCommon sildenafil side effects may include:\nflushing (warmth, redness, or tingly feeling);\nheadache, dizziness;\nheartburn, nausea, or upset stomach\nabnormal vision (blurred vision, changes in color vision)\nrunny or stuffy nose, nosebleeds;\nsleep problems (insomnia); or\nmuscle pain, back pain.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sildenafil side effects (more detail)\n','Sildenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.\nSildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men.\nAnother brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.\nDo not take Viagra while also taking Revatio.\n','Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as \"poppers\". Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.\nSome medicines can cause unwanted or dangerous effects when used with sildenafil. Tell your doctor about all your current medicines, especially riociguat (Adempas). Do not take sildenafil with riociguat.\nContact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.\nStop using sildenafil and get emergency medical help if you have sudden vision loss.\nBefore taking this medicine\nYou should not use sildenafil if you are allergic to it, or:\nif you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).\nDo not take this medicine if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (\"poppers\"). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.\nTo make sure sildenafil is safe for you, tell your doctor if you have ever had:\nheart problems (chest pain, a heart rhythm disorder, heart attack);\nhigh or low blood pressure;\nblood circulation problems;\nretinitis pigmentosa (an inherited condition of the eye);\nblindness in one or both eyes;\nbleeding problems;\na stomach ulcer;\npulmonary veno-occlusive disease (PVOD);\nliver or kidney disease;\na blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;\na physical deformity of the penis (such as Peyronie\'s disease); or\nif you have been told you should not have sexual intercourse for health reasons.\nSildenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether this medicine is the actual cause of vision loss.\nThis medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Women with pulmonary arterial hypertension should not stop taking sildenafil without talking to their doctor.\nIt is not known whether sildenafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Women with pulmonary arterial hypertension should not stop taking sildenafil without talking to their doctor.\nDo not give this medication to anyone under 18 years old without medical advice.\n','Drinking alcohol with sildenafil can cause side effects.\nGrapefruit may interact with sildenafil and lead to unwanted side effects. Avoid the use of grapefruit products.\nAvoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.\n'),(797,'simethicone','Use exactly as directed on the label, or as prescribed by your doctor.\nDo not take more of this medicine than directed.\nSimethicone works best if you take it after meals and at bedtime.\nYou must chew the chewable tablet before you swallow it.\nMeasure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).\nSimethicone liquid drops can be mixed with water, baby formula, or other liquids to make swallowing easier for an infant or child.\nAlways follow directions on the medicine label about giving simethicone to a child. Call your doctor if the child\'s gas symptoms do not improve after treatment with simethicone.\nYou may need to follow a special diet or increase your exercise while using simethicone. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.\nStore at room temperature away from moisture, heat, and light. Do not allow the liquid form of this medicine to freeze.\n Detailed Simethicone dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\nWhat happens if I miss a dose?\nSince simethicone is used when needed, you may not be on a dosing schedule. Skip any missed dose if it\'s almost time for your next dose. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may affect simethicone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Simethicone drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.\nLess serious side effects may be more likely, and you may have none at all.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Simethicone side effects (more detail)\n','Simethicone is used to relieve painful pressure caused by excess gas in the stomach and intestines. Simethicone is for use in babies, children, and adults.\nSimethicone may also be used for purposes not listed in this medication guide.\n','Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.\nBefore taking this medicine\nYou should not use simethicone if you are allergic to it.\nAsk a doctor or pharmacist if it is safe for you to take  simethicone if you are allergic to any drugs, or if you have any type of serious illness (especially one that affects your stomach or intestines).\nAsk a doctor before using this medicine if you are pregnant or breastfeeding.\nThe liquid form may contain phenylalanine. Talk to your doctor before using this form of simethicone if you have phenylketonuria (PKU).\n','Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids may contain simethicone.\n'),(798,'simvastatin','Take simvastatin exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.\nSimvastatin is usually taken at bedtime or with an evening meal. If you take simvastatin more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.\nWhile using simvastatin, you may need frequent blood tests at your doctor\'s office.\nYou may need to take simvastatin on a long-term basis for the treatment of high cholesterol. You may need to stop using this medicine for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.\nSimvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.\nStore at room temperature away from moisture, heat, and light.\n Detailed Simvastatin dosage information\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Many drugs can interact with simvastatin. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment, especially:\ndelavirdine;\nfenofibrate; or\nfluconazole.\nThis list is not complete and many other drugs can interact with simvastatin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.\n Simvastatin drug interactions (more detail)\n','Get emergency medical help if you have any of these signs of an allergic reaction to simvastatin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nIn rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.\nAlso call your doctor at once if you have:\nsigns of a kidney problem - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; or\nmuscle weakness in your hips, shoulders, neck, and back;\ntrouble lifting your arms, trouble climbing or standing; or\nliver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).\nCommon simvastatin side effects may include:\nheadache;\nconstipation, nausea, stomach pain; or\ncold symptoms such as stuffy nose, sneezing, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Simvastatin side effects (more detail)\n','Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or \"statins.\"\nSimvastatin is used to lower blood levels of \"bad\" cholesterol (low-density lipoprotein, or LDL), to increase levels of \"good\" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).\nSimvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.\nSimvastatin is used in adults and children who are at least 10 years old.\n','In rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.\nNever take simvastatin in larger amounts, or for longer than recommended by your doctor. Follow your doctor\'s dosing instructions very carefully. Taking too much of this medication may cause serious or life-threatening side effects.\nBefore taking this medicine, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, if you are of Chinese descent, or if you drink more than 2 alcoholic beverages daily.\nSimvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant or planning to become pregnant.\nGrapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Do not consume grapefruit products while taking this medication.\nSome medicines can cause unwanted or dangerous effects when used with simvastatin. Your doctor may need to change your treatment plan if you use certain antibiotics or antifungal medicines, hepatitis C medication, heart medication, or medicines to treat HIV/AIDS.\nStop taking this medication and tell your doctor right away if you become pregnant.\nBefore taking this medicine\nYou should not take this medicine if you are allergic to simvastatin, if you are pregnant or breast-feeding, or if you have active liver disease.\nThe following drugs can increase your risk of serious muscle problems if you take them together with simvastatin. These drugs should not be used while you are taking this medicine:\ncyclosporine;\ndanazol;\ngemfibrozil;\nnefazodone;\nan antibiotic - clarithromycin, erythromycin, telithromycin;\nantifungal medication - itraconazole, ketoconazole, posaconazole, voriconazole;\nhepatitis C medications - boceprevir, telaprevir; or\nHIV/AIDS medication - atazanavir, cobicistat (Stribild, Tybost), darunavir, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir.\nBefore you start taking simvastatin, tell your doctor if you are already using any of these other medicines:\nlomitapide; or\nheart medication - amiodarone, amlodipine, diltiazem, dronedarone, ranolazine, verapamil.\nTo make sure simvastatin is safe for you, tell your doctor if you have:\nhistory of liver disease;\nhistory of kidney disease;\ndiabetes;\na thyroid disorder; or\nif you drink more than 2 alcoholic beverages daily.\nSimvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).\nFDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not take simvastatin if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking this medicine.\nSimvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking this medicine.\n Simvastatin pregnancy and breastfeeding warnings (more detail)\n','Grapefruit and grapefruit juice may interact with simvastatin and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.\nAvoid eating foods that are high in fat or cholesterol. Simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.\nAvoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.\n'),(799,'sinemet','Usual Adult Dose for Parkinson\'s Disease:\nOptimum dosage is determined by careful individual titration: All doses expressed as CARBIDOPA-LEVODOPA\nImmediate-release tablets:\nInitial dose: 25 mg-100 mg orally three times a day or 10 mg-100 mg orally 3 or 4 times a day\n-Increase by 1 tablet every day or every other day as needed until a dose of 8 tablets is reached; may use a combination of tablets from both ratios (1:4 or 1:10) to provide the optimum dose.\nConversion from LEVODOPA:\n-Levodopa should be discontinued at least 12 hours before starting carbidopa-levodopa; initiate with approximately 25% of the previous levodopa dose.\n-Suggested dose for patients receiving less than levodopa 1500 mg per day: 25 mg-100 mg orally 3 or 4 times a day.\n-Suggested dose for patients receiving more than levodopa 1500 mg per day: 25 mg-250 mg orally 3 or 4 times a day.\nSustained-Release Tablets (Sinemet CR):\n-Initial dose (levodopa-naive): 50 mg-200 mg orally twice a day; initial dosage should be given at intervals of more than 6 hours\n-Dose and dosing interval may be increased or decreased at intervals of at least 3 days based on therapeutic response\n-Dose range: Most patients will require levodopa 400 to 1600 mg/day in divided doses every 4 to 8 hours during waking hours; doses of 2400 mg/day at intervals of less than 4 hours have been used, but are generally not recommended.\nConversion from IMMEDIATE-RELEASE levodopa with or without a decarboxylase inhibitor:\n-For patients receiving levodopa with a decarboxylase inhibitor: Dosage with Sinemet CR should be approximately 10% higher than previous levodopa dosage; this may need to be increased to up to 30% higher depending on clinical response.\n-For patients receiving levodopa without a decarboxylase inhibitor: Dosage with sustained release should be approximately 25% of previous levodopa dosage; levodopa should be discontinued at least 12 hours before starting carbidopa-levodopa.\n Detailed Sinemet dosage information\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nGet your prescription refilled before you run out of medicine completely.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with carbidopa and levodopa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Sinemet drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Sinemet: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nCall your doctor at once if you have:\nuncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);\nworsening of tremors (uncontrolled shaking);\nsevere or ongoing vomiting or diarrhea;\nconfusion, hallucinations, unusual changes in mood or behavior;\ndepression or suicidal thoughts; or\nsevere nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.\nSome people taking Sinemet have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.\nYou may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.\nYou may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.\nCommon Sinemet side effects may include:\njerky or twisting muscle movements;\nheadache, dizziness;\nlow blood pressure (feeling light-headed);\nsleep problems, strange dreams;\ndry mouth;\nmuscle contractions; or\nnausea, vomiting, constipation.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sinemet side effects (more detail)\n','Sinemet contains a combination of carbidopa and levodopa.\nSinemet is used to treat symptoms of Parkinson\'s disease, such as muscle stiffness, tremors, spasms, and poor muscle control. Parkinson\'s disease may be caused by low levels of a chemical called dopamine (DOE pa meen) in the brain.\nSinemet is also used to treat Parkinson symptoms caused by carbon monoxide carbon monoxide poisoning or manganese intoxication.\n','You should not use Sinemet if you have narrow-angle glaucoma.\nDo not use Sinemet if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.\nBefore taking this medicine\nYou should not use Sinemet if you are allergic to carbidopa or levodopa, or if you have:\nnarrow-angle glaucoma.\nDo not use Sinemet if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.\nTo make sure Sinemet is safe for you, tell your doctor if you have:\nheart disease, high blood pressure, or heart attack;\nliver or kidney disease;\nan endocrine (hormonal) disorder;\nasthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;\na stomach or intestinal ulcer;\nopen-angle glaucoma; or\ndepression, mental illness, or psychosis.\nPeople with Parkinson\'s disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.\nTell your doctor if you are pregnant or breastfeeding.\nThe disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).\nHow should I take Sinemet?\nTake Sinemet exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nIf you already take levodopa, you must stop taking it at least 12 hours before you start taking Sinemet.\nSinemet can be taken with or without food. Take your doses at regular intervals to keep a steady amount of the drug in your body at all times.\nThe tablet is sometimes broken in half to give the correct dose. Always swallow a whole or half tablet without chewing or crushing.\nIt may take up to several weeks of using Sinemet before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after a few weeks of treatment. Also tell your doctor if the effects of this medication seem to wear off quickly in between doses.\nIf you use Sinemet long-term, you may need frequent medical tests at your doctor\'s office.\nThis medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Sinemet.\nDo not stop using Sinemet suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.\nStore at room temperature away from moisture, heat, and light.\n','Avoid driving or hazardous activity until you know how Sinemet will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.\nAvoid taking iron supplements or eating a diet that is high in protein (protein sources include meat, eggs, and cheese). These things can make it harder for your body to digest and absorb carbidopa and levodopa. Talk with your doctor or dietitian about the best foods to eat while you are taking this medicine.\n'),(800,'singulair','Usual Adult Dose of Singulair for Allergic Rhinitis:\n-10 mg orally once a day\nComments:\n-For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion.\n-For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion.\n-Patients with both asthma and allergic rhinitis should take only one dose daily in the evening.\nUses:\n-Prophylaxis and chronic treatment of asthma\n-Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis\nUsual Adult Dose of Singulair for Asthma -- Maintenance:\n-10 mg orally once a day\nComments:\n-For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion.\n-For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion.\n-Patients with both asthma and allergic rhinitis should take only one dose daily in the evening.\nUses:\n-Prophylaxis and chronic treatment of asthma\n-Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis\nUsual Adult Dose for Bronchospasm Prophylaxis:\n-10 mg orally once a day at least 2 hours before exercise\nComments:\n-An additional dose should not be taken within 24 hours of a previous dose.\n-Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB.\n-A rescue short-acting beta-agonist should be available at all times.\n-Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB.\nUse: Prevention of exercise-induced bronchoconstriction (EIB)\nUsual Pediatric Dose of Singulair for Asthma -- Maintenance:\nLess than 12 months: Not approved.\n12 to 23 months:\n-One sachet of 4 mg oral granules once a day\n2 to 5 years:\n-4 mg chewable tablet or one sachet oral granules once a day\n6 to 14 years:\n-5 mg chewable tablet orally once a day\n15 years or older:\n-10 mg tablet orally once a day\nComments:\n-Doses should be taken in the evening.\n-Efficacy has been demonstrated for asthma when this drug was administered in the evening without regard to time of food ingestion.\nUse: Prophylaxis and chronic treatment of asthma in pediatric patients 12 months of age and older\nUsual Pediatric Dose of Singulair for Allergic Rhinitis:\nSeasonal Allergic Rhinitis:\nLess than 2 years: Not approved.\n2 to 5 years:\n-4 mg chewable tablet or one sachet of 4 mg oral granules once a day\n6 to 14 years:\n-5 mg chewable tablet orally once a day\n15 years or older:\n-10 mg tablet orally once a day\nPerennial Allergic Rhinitis:\nLess than 6 months: Not approved.\n6 to 23 months:\n-One sachet of 4 mg oral granules once a day\n2 to 5 years:\n-4 mg chewable tablet orally once a day\n6 to 14 years:\n-5 mg chewable tablet orally once a day\n15 years or older:\n-10 mg tablet orally once a day\nComments:\n-Efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion.\n-The time of administration may be individualized to suit patient needs.\nUses:\n-Relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older\n-Relief of symptoms of perennial allergic rhinitis in patients 6 months of age and older\nUsual Pediatric Dose for Bronchospasm Prophylaxis:\nLess than 6 years: Not approved.\n6 to 14 years:\n-5 mg chewable tablet orally once a day\n15 years or older:\n-10 mg tablet orally once a day\nComments:\n-Dose should be taken at least 2 hours before exercise.\n-An additional dose should not be taken within 24 hours of a previous dose.\n-Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB.\n-A rescue short-acting beta-agonist should be available at all times.\n-Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB.\nUse: Prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older\n Detailed Singulair dosage information\nWhat happens if I miss a dose?\nSkip the missed dose and use your next dose at the regular time. Do not use two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222.\n','Other drugs may interact with montelukast, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.\n Singulair drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction to Singulair: hives, blisters, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat.\nTell your doctor right away if you have signs of blood vessel inflammation: flu-like symptoms, severe sinus pain, a skin rash, numbness or a \"pins and needles\" feeling in your arms or legs.\nSome people using Singulair have had new or worsening mental problems. Stop taking this medicine and call your doctor right away if you have unusual changes in mood or behavior, such as:\nagitation, aggression, feeling restless or irritable;\nanxiety, depression, confusion, problems with memory or attention;\nstuttering, tremors, uncontrolled muscle movements;\nsuicidal thoughts or actions;\nhallucinations, sleep problems, vivid, dreams, sleep-walking; or\ncompulsive or repetitive behaviors.\nCommon Singulair side effects may include:\nstomach pain, diarrhea;\nfever or other flu symptoms;\near pain or full feeling, trouble hearing;\nheadache; or\ncold symptoms such as runny or stuffy nose, sinus pain, cough, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Singulair side effects (more detail)\n','Singulair (montelukast) is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.\nSingulair is used to prevent asthma attacks in adults and children as young as 12 months old. Singulair is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.\nSingulair is also used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. It is also used to treat symptoms of seasonal allergies in adults and children who are at least 2 years old.\nSingulair is used for allergies, only after other treatments have failed.\nIf you already take Singulair to prevent asthma or allergy symptoms, do not use an extra dose to treat exercise-induced bronchoconstriction.\n','Some people using Singulair have had new or worsening mental problems. Stop taking montelukast and call your doctor right away if you have any unusual changes in mood or behavior (such as anger, aggression, confusion, sleep problems, compulsive behaviors, hallucinations, or suicidal thoughts or actions).\nTell your doctor right away if you have signs of blood vessel inflammation: flu-like symptoms, severe sinus pain, a skin rash, numbness or a \"pins and needles\" feeling in your arms or legs.\nSingulair will not work fast enough to treat an asthma attack that has already begun. Use only a fast-acting inhalation medicine to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing attacks.\nCall your doctor right away if you feel that Singulair is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.\nIf you already take Singulair to prevent asthma or allergy symptoms, do not use it for exercise-induced bronchoconstriction.\nIt may take up to several weeks before your symptoms improve. Keep using Singulair as directed and tell your doctor if your symptoms do not improve after several weeks of treatment.\nBefore taking this medicine\nYou should not use Singulair if you are allergic to montelukast.\nTo make sure Singulair is safe for you, tell your doctor if you have ever had:\nmental illness or psychosis; or\nasthma, or a history of severe allergic reaction (sneezing, runny or stuffy nose, wheezing, shortness of breath) after taking aspirin or another NSAID.\nThe chewable tablet may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).\nTell your doctor if you are pregnant or breastfeeding.\nDo not give Singulair to a child without a doctor\'s advice.\nHow should I take Singulair?\nTake Singulair exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.\nSingulair is usually taken once daily in the evening for prevention of asthma or allergy symptoms. For exercise-induced bronchoconstriction, take a single dose at least 2 hours before you exercise, and do not take another dose for at least 24 hours. Follow your doctor\'s instructions.\nSingulair is not a rescue medicine for asthma or bronchospasm attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well.\nSwallow the regular tablet whole, with a glass of water.\nYou must chew the Singulair chewable tablet before you swallow it.\nThe oral granules can be placed directly into the mouth and swallowed, or mixed with a spoonful of applesauce, mashed carrots, rice, or ice cream. Oral granules can also be mixed with 1 teaspoon of baby formula or breast milk. Do not use any other type of liquid for mixing the granules.\nAfter opening or mixing the Singulair oral granules, you must use them within 15 minutes. Do not save an open packet or mixed medicine for later use.\nIt may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.\nUse all asthma medications as directed. Your dose needs may change due to surgery, illness, stress, or a recent asthma attack. Do not change your dose or dosing schedule without your doctor\'s advice. Tell your doctor if any of your medicines seem to stop working.\nIf you also use an oral steroid medication, you should not stop using it suddenly. Follow your doctor\'s instructions about tapering your dose.\nStore Singulair at room temperature away from moisture and heat. Do not open a packet of oral granules until you are ready to use the medicine.\n','Avoid situations or activities that may trigger an asthma attack.\nIf your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.\n'),(801,'sitagliptin','Usual Adult Dose for Diabetes Type 2:\n100 mg orally once a dayComments: -When used in combination with an insulin secretagogue (e.g.  sulfonylurea) or insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.  Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.\n Detailed Sitagliptin dosage information\nFree Drugs.com Discount Card\nSave up to 80% on your prescriptions.\nAccepted at over 65,000 pharmacies.\nGet Discount Card\n','Sitagliptin may not work as well when you use other medicines at the same time. Many other drugs can also affect blood sugar control.\nYou may be more likely to have low blood sugar if you also use insulin.\nOther drugs may affect sitagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.\n Sitagliptin drug interactions (more detail)\n','Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).\nStop taking sitagliptin and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, with or without vomiting.\nCall your doctor at once if you have:\nsevere autoimmune reaction--itching, blisters, breakdown of the outer layer of skin;\nsevere or ongoing pain in your joints;\nlittle or no urination; or\nsymptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nCommon side effects may include:\nlow blood sugar;\nheadache; or\nrunny or stuffy nose, sore throat.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\n Sitagliptin side effects (more detail)\n','Sitagliptin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Sitagliptin is not for treating type 1 diabetes.\nSitagliptin may also be used for purposes not listed in this medication guide.\n','Call your doctor if you have symptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.\nStop taking sitagliptin and call your doctor if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, with or without vomiting.\nBefore taking this medicine\nYou should not use sitagliptin if you are allergic to it, or if you have diabetic ketoacidosis (call your doctor for treatment with insulin).\nTell your doctor if you have ever had:\nkidney disease (or if you are on dialysis);\nheart problems;\npancreatitis;\nhigh triglycerides (a type of fat in the blood);\ngallstones; or\nalcoholism.\nFollow your doctor\'s instructions about using  sitagliptin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.\nYour name may need to be listed on a sitagliptin pregnancy registry when you start using this medicine.\nIt may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.\nSitagliptin is not approved for use by anyone younger than 18 years old.\nHow should I take sitagliptin?\nFollow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.\nYou may take this medicine with or without food. Follow your doctor\'s instructions.\nYour blood sugar will need to be checked often, and you may need other blood tests at your doctor\'s office.\nYou may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).\nYour doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.\nAlso watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.\nBlood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.\nSitagliptin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor\'s instructions very closely.\nStore at room temperature away from moisture, heat, and light.\nWhat happens if I miss a dose?\nTake the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).\n','Follow your doctor\'s instructions about any restrictions on food, beverages, or activity.\n'),