Before you start treatment with Enbrel, your doctor may perform tests to make sure you do not have an infection.
Enbrel is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
Do not shake this medicine. Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.
You may need to mix Enbrel with a liquid (diluent). When using injections by yourself, be sure you understand how to properly mix and store the medicine.
Etanercept doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.
If you need surgery, tell the surgeon ahead of time that you are using Enbrel.p
Enbrel affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.
If you've ever had hepatitis B, using Enbrel can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.
Carefully follow all storage instructions provided with your medicine.
Store Enbrel in the refrigerator at 36°F to 46°F (2°C to 8°C).
Store Enbrel in the original carton to protect from light or physical damage.
If needed, you may store the Enbrel prefilled syringe or the unmixed Enbrel multiple-dose vial and diluent syringe (dose tray) at room temperature between 68°F to 77°F (20°C to 25°C) for up to 14 days.
Once an Enbrel prefilled syringe or an unmixed multiple-dose vial has reached room temperature, do not put it back in the refrigerator.
Throw away any Enbrel that has been stored at room temperature after 14 days.
A mixed (reconstituted) Enbrel multiple-dose vial should be used right away or kept in the refrigerator at 36°F to 46°F (2°C to 8°C) for up to 14 days.
Do not store the Enbrel in extreme heat or cold. For example, avoid storing Enbrel in your vehicle’s glove box or trunk.
Do not use after the expiration date on the label has passed.
Do not freeze.
Do not shake.
Each cartridge, injection pen, or prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
 Detailed Enbrel dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose of Enbrel.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
