Get emergency medical help if you have signs of an allergic reaction to Iclusig: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Iclusig may cause heart or blood vessel problems that could lead to heart attack or stroke. Call your doctor right away or get emergency medical help if you have:
heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, feeling short of breath;
signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; or
signs of a blood clot - severe stomach pain, pain or swelling in your arms or legs, coughing up blood.
Call your doctor at once if you have:
dizziness, confusion, headache, change in mental status;
a seizure;
swelling, rapid weight gain, feeling short of breath;
a wound that will not heal;
eye problems - vision problems, eye pain or swelling, bleeding in the eye, increased sensitivity to light, flashes of light or "floaters" in your vision;
heart problems - chest pain, shortness of breath, fast or pounding heartbeats, feeling like you might pass out;
a hole or tear in your stomach or intestine - severe pain or swelling in your stomach with a high fever;
low blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet;
nerve problems - muscle weakness, trouble moving your eyes or other parts of your face, tingling, burning pain, numbness in your hands and feet;
severe bleeding - nosebleeds, bloody or tarry stools, pink or brown urine, heavy menstrual periods, coughing up blood or vomit that is bloody or looks like coffee grounds; or
signs of liver or pancreas problems - loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes).
Common Iclusig side effects include:
dry skin, rash;
stomach pain, nausea, vomiting, diarrhea, constipation;
headache, muscle or joint pain;
pain in your arms, hands, legs, or feet;
increased blood pressure; or
fever, tired feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Iclusig side effects (more detail)
