When you start or stop taking rosuvastatin, your doctor may need to adjust the doses of any other medicines you take on a regular basis. Using certain medicines together with rosuvastatin can increase your risk of serious muscle problems. It is very important to tell your doctor about all medicines you use, and those you start or stop using during your treatment with rosuvastatin, especially:
colchicine;
cyclosporine;
antifungal medicine--fluconazole, itraconazole, ketoconazole;
antiviral medicine to treat HIV or hepatitis C--atazanavir, fosamprenavir, ledipasvir, lopinavir, ritonavir, simeprevir, sofosbuvir, tipranavir, Epclusa, Mavyret, Viekira, Vosevi, and others;
a blood thinner--warfarin, Coumadin, Jantoven;
cancer medicine--darolutamide, regorafenib;
medicines that contain niacin or nicotinic acid--vitamin B3, Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others; or
other cholesterol medications--fenofibrate, gemfibrozil.
This list is not complete. Other drugs may affect rosuvastatin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Rosuvastatin drug interactions (more detail)
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