Do not use  carbidopa and levodopa if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.
Before taking this medicine
You should not use this medicine if you are allergic to carbidopa or levodopa, or if you have:
narrow-angle glaucoma.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
Tell your doctor if you have ever had:
heart disease, high blood pressure, or heart attack;
liver or kidney disease;
an endocrine (hormonal) disorder;
asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;
a stomach or intestinal ulcer;
open-angle glaucoma; or
depression, mental illness, or psychosis.
The disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.
Tell your doctor if you are pregnant or breastfeeding.
