You should not use Mavyret if you have severe liver disease, or if you also take atazanavir or rifampin.
If you've ever had hepatitis B, it may become active or get worse after you stop using Mavyret.
Before taking this medicine
You should not use Mavyret if you are allergic to glecaprevir or pibrentasvir, or if:
you have severe liver disease; or
you also take atazanavir or rifampin.
To make sure Mavyret is safe for you, tell your doctor if you have ever had:
hepatitis B;
liver problems other than hepatitis;
a liver or kidney transplant;
HIV (human immunodeficiency virus); or
an opioid addiction or past use of injected drugs.
Tell your doctor if you are pregnant or breastfeeding.
Mavyret should not be given to a child younger than 12 years old, or weighing less than 99 pounds (45 kilograms).
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
How should I take Mavyret?
Take Mavyret exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Mavyret.
Mavyret is usually taken as 3 tablets daily, taken all at once, for 8 to 16 weeks.
Take with food.
You will need frequent blood tests to check your liver function.
You should not stop using Mavyret suddenly. Stopping suddenly could make your condition harder to treat with hepatitis C antiviral medicine.
Use all hepatitis C medications as directed and read all medication guides you receive. Do not change your dose or stop using a medicine without your doctor's advice. Every person with hepatitis C should remain under the care of a doctor.
If you've ever had hepatitis B, this virus may become active or get worse in the months after you stop using Mavyret. You may need frequent liver function tests while using this medicine and for several months after your last dose.
Store this medicine in the original container at room temperature away from moisture and heat. Keep each tablet in the foil blister pack until you are ready to take it.
