Avoid exposure to sunlight or tanning beds. Rapamune may increase your risk of skin cancer. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid getting Rapamune oral liquid on your skin. Wash the skin with soap and water if this happens. If the medicine gets into your eyes, rinse them with plain water.
Grapefruit may interact with sirolimus and lead to unwanted side effects. Avoid the use of grapefruit and grapefruit juice while taking Rapamune.
Do not receive a "live" vaccine while using Rapamune. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).
