Get emergency medical help if you have signs of an allergic reaction to Imfinzi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel light-headed or itchy, or if you have a fever, chills, neck or back pain, trouble breathing, or flushing (warmth, redness, or tingly feeling).
Durvalumab causes your immune system to attack tumor cells, but it could also attack healthy organs and tissues in your body. This could lead to serious or life-threatening side effects on your lungs, liver, pancreas, kidneys, intestines, thyroid, or adrenal glands.
Call your doctor at once if you have:
chest pain, new or worsening cough, feeling short of breath;
severe stomach pain, diarrhea, bloody or tarry stools;
new or worsening skin rash, itching, or blistering;
fever, flu-like symptoms;
pain or burning when you urinate;
problems in other organs - mood or behavior changes, neck stiffness, confusion, eye pain or redness, vision problems;
liver problems - loss of appetite, upper stomach pain, drowsiness, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes);
kidney problems - little or no urination, red or pink urine, swelling in your feet or ankles;
transplant rejection - rash with blisters and peeling, watery diarrhea, stomach pain, vomiting, loss of appetite, fever, bruising or bleeding, jaundice, pain or swelling near your transplanted organ; or
signs of a hormonal disorder - unusual headaches, feeling light-headed or very tired, hoarse or deepened voice, increased hunger or thirst, increased urination, constipation, vomiting, hair loss, feeling cold, weight gain, or weight loss.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Imfinzi side effects may include:
nausea, constipation;
decreased appetite;
feeling weak or tired;
bone or muscle pain;
cough, feeling short of breath;
cold symptoms such as stuffy nose, sneezing, sore throat;
painful urination;
hair loss;
rash; or
swelling in your arms and legs.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Imfinzi side effects (more detail)
