You should not take Triumeq if you have ever had an allergic reaction to any medicine that contains abacavir, or if you have a gene variation called HLA-B*5701 allele. Also, you should not use this medicine if you have moderate or severe liver disease, or if you are also taking dofetilide (Tikosyn).
Stop using Triumeq and call your doctor at once if you have any of these signs of an allergic reaction to this medicine: fever; rash; nausea, vomiting, diarrhea, stomach pain; general ill feeling, extreme tiredness, body aches; shortness of breath, cough, sore throat.
If you've ever had hepatitis B, it may become active or get worse after you stop using Triumeq. You may need frequent liver function tests for several months.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.
Before taking this medicine
You should not use Triumeq if you are allergic to abacavir, dolutegravir, or lamivudine, or if:
you also take dofetilide (Tikosyn);
you have moderate or severe liver disease;
you have a gene variation called HLA-B*5701 allele (your doctor will test you for this); or
you have a history of allergic reaction to Combivir, Dutrebis, Epivir, Epzicom, Tivicay, Trizivir, or Ziagen.
To make sure Triumeq is safe for you, tell your doctor if you have:
liver disease (especially hepatitis B or C);
heart problems or risk factors such as diabetes, smoking, high blood pressure, high cholesterol; or
kidney disease.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you are overweight, or if you are a woman. Ask your doctor about your risk.
You may need to have a negative pregnancy test before starting this treatment.
Abacavir, dolutegravir, or lamivudine could harm an unborn baby if you take this medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
If you are pregnant, use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.
Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
How should I take Triumeq?
Take Triumeq exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
You may take Triumeq with or without food.
Triumeq comes with a Medication Guide and a Warning Card listing symptoms of an allergic reaction. Read this information and learn what symptoms to watch for. Keep the Wallet Card with you at all times.
You may need to take an extra daily dose of dolutegravir (Tivicay) if you take Triumeq with certain other medicines.
Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or stop using a medicine without your doctor's advice. Every person with HIV should remain under the care of a doctor.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
If you've ever had hepatitis B, this virus may become active or get worse in the months after you stop using Triumeq. You may need frequent liver function tests while using this medicine and for several months after your last dose.
