Ibrance affects your lungs or your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, chest pain, shortness of breath, or cough with or without mucus.
Before taking this medicine
You should not use Ibrance if you are allergic to palbociclib. Tell your doctor if you have signs of infection (such as fever or chills).
To make sure Ibrance is safe for you, tell your doctor if you have ever had:
liver disease; or
kidney disease.
Palbociclib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
If you are a woman, do not use palbociclib if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Ibrance.
This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because palbociclib can harm an unborn baby.
You should not breastfeed while using palbociclib and for at least 3 weeks after your last dose.
How should I take Ibrance?
Take Ibrance exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Ibrance is given in a 28-day treatment cycle, and you may only need to take the medicine during the first 3 weeks of each cycle. Your doctor will determine how long to treat you with Ibrance.
Take Ibrance capsules with food. Avoid grapefruit products. Grapefruit may interact with palbociclib and lead to unwanted side effects.
You may take Ibrance tablets with or without food.
Take the medicine at the same time each day.
Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Do not use a broken or damaged pill.
If you vomit after taking Ibrance, wait until the next day to take your next dose.
Palbociclib affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.
Store at room temperature away from moisture and heat.
