Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using oxymetazoline nasal and call your doctor at once if you have:
ongoing or worsening symptoms;
severe burning or stinging in your nose after using the nasal spray;
chest pain, fast or uneven heart rate; or
severe headache, buzzing in your ears, anxiety, confusion, or feeling short of breath.
Common side effects may include:
mild burning or stinging of the nose;
sneezing; or
runny nose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Oxymetazoline nasal side effects (more detail)
