Do not use Aubagio if you are pregnant or may become pregnant.
Teriflunomide can cause severe liver problems. You should not use this medicine if you have severe liver disease or if you are also taking leflunomide (Arava). Tell your doctor if you have a history of liver disease.
Call your doctor at once if you have signs of liver problems: upper stomach pain, loss of appetite, dark urine, or jaundice (yellowing of the skin or eyes).
Your doctor may need to test your liver function up to 6 months before you start taking Aubagio, and then every month when you first start taking this medicine.
Teriflunomide can lower blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill. While using Aubagio, you may need blood tests every 6 months. Your blood pressure will also need to be checked often.
After you stop taking Aubagio, the drug could stay in your body for up to 2 years. You may need to be treated with other medications to help your body eliminate teriflunomide quickly. Follow your doctor's instructions.
Before taking this medicine
You should not use Aubagio if you are allergic to teriflunomide or leflunomide, or if:
you have severe liver disease; or
you are also taking leflunomide (Arava).
Do not use Aubagio if you are pregnant or may become pregnant You will need to have a negative pregnancy test before starting this treatment. Avoid getting pregnant until after you stop taking this medicine and undergo a "drug elimination" procedure to help rid your body of this medicine. Stop taking Aubagio and call your doctor right away if you miss a period or think you might be pregnant.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
liver or kidney disease;
high blood sugar;
high blood pressure;
skin problems when taking medicines;
a fever, or uncontrolled infections;
breathing problems;
tuberculosis; or
nerve problems, such as neuropathy.
Use birth control to prevent pregnancy while you are taking this medicine. After you stop taking Aubagio, continue using birth control until you have received blood tests to make sure the drug has been eliminated from your body.
If you become pregnant while taking Aubagio or within 2 years after you stop, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of teriflunomide on the baby.
If you are a man, use effective birth control to prevent pregnancy if your sex partner is able to get pregnant. After your treatment ends, keep using birth control until you have received the medications to help your body eliminate teriflunomide.
You should not breastfeed while using this medicine.
How should I take Aubagio?
Before you start treatment with Aubagio, your doctor may perform tests to make sure you do not have tuberculosis or other infections.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take Aubagio with or without food.
Your blood pressure will need to be checked often.
Teriflunomide can lower your blood cell counts. Your blood will need to be tested often. Your treatment may be delayed based on the results.
After you stop taking Aubagio, you may need to be treated with other medicines to help your body eliminate teriflunomide quickly. If you do not undergo this drug elimination procedure, teriflunomide could stay in your body for up to 2 years. Follow your doctor's instructions.
You will also need to go through this drug elimination procedure if you plan to become pregnant after you stop taking this medicine.
Store at room temperature away from moisture and heat.
