Jakafi (ruxolitinib) works by blocking certain enzymes in the body that affect blood cell production.
Jakafi is used in adults to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that that affect your body's ability to produce blood cells.
Jakafi is also used to treat acute graft versus host disease (GVHD) in adults and children 12 years of age and older who have taken corticosteroids and they did not work well enough.
Jakafi is usually given after other treatments have failed.
