Administration
Ophthalmic Administration
Apply topically to the affected eye(s) as an ophthalmic emulsion (latanoprost) or ophthalmic solution (latanoprost alone or in fixed combination with netarsudil).        
Avoid contamination of the dispensing container.   (See Bacterial Keratitis under Cautions.)
Remove contact lenses before administering each dose; may reinsert lenses 15 minutes after the dose.  
If more than one topical ophthalmic preparation is used, administer the preparations at least 5 minutes apart.  
Dosage
Adults
Ocular Hypertension and Glaucoma
Ophthalmic
Latanoprost 0.005% ophthalmic solution or emulsion: One drop in the affected eye(s) once daily in the evening.       
Netarsudil 0.02% and latanoprost 0.005% ophthalmic solution: One drop in the affected eye(s) once daily in the evening.
More frequent dosing may diminish the IOP-lowering effect of latanoprost or cause paradoxical elevation of IOP.     
If target IOP not achieved, may initiate additional or alternative ocular hypotensive agents.   (See Ocular Hypertension and Glaucoma under Uses.) However, concomitant use of ≥2 prostaglandin analogs not recommended. 
If a dose is missed, continue the usual schedule with the next dose applied the following evening.   
Special Populations
No special population dosage recommendations at this time.  
 Detailed Latanoprost ophthalmic dosage information
