Tell your doctor about all your current medicines. Many drugs can affect vortioxetine, especially:
any other antidepressant;
buspirone;
fentanyl, tramadol;
lithium;
St. John's wort, tryptophan (sometimes called L-tryptophan);
a blood thinner (warfarin, Coumadin, Jantoven);
a diuretic or "water pill";
migraine headache medicine (triptans);
NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or
seizure medicine--carbamazepine, phenytoin.
This list is not complete and many other drugs may affect vortioxetine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Vortioxetine drug interactions (more detail)
