Smoking can make Ofev less effective. Avoid smoking while taking this medicine, or try to quit before you start this treatment.
Avoid taking an herbal supplement containing St. John's wort.
Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with nintedanib may cause you to bruise or bleed easily.
