Ask a doctor or pharmacist if it is safe for you to use oxymetazoline nasal if you are also using any of the following drugs:
an antidepressant--amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline;
ergot medicine--ergotamine, dihydroergotamine, ergonovine, methylergonovine; or
an MAO inhibitor--isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine.
This list is not complete and other drugs may interact with oxymetazoline nasal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
 Oxymetazoline nasal drug interactions (more detail)
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