Usual Adult Dose for Osteoarthritis:
Immediate Release:
-Initial dose: 300 mg orally 2 to 3 times a day or 400 mg to 500 mg orally twice a day
-Maintenance dose: A lower dose of 600 mg/day may suffice for long-term use
-Maximum dose: 1000 mg/day
Extended Release: 400 mg to 1000 mg orally once a day
Comments:
-Therapeutic response can be seen within 1 week of therapy, however, is most often observed by 2 weeks; doses should be adjusted accordingly after satisfactory response is achieved.
Uses: For acute and long-term use in the management of signs and symptoms of osteoarthritis and rheumatoid arthritis
Usual Adult Dose for Rheumatoid Arthritis:
Immediate Release:
-Initial dose: 300 mg orally 2 to 3 times a day or 400 mg to 500 mg orally twice a day
-Maintenance dose: A lower dose of 600 mg/day may suffice for long-term use
-Maximum dose: 1000 mg/day
Extended Release: 400 mg to 1000 mg orally once a day
Comments:
-Therapeutic response can be seen within 1 week of therapy, however, is most often observed by 2 weeks; doses should be adjusted accordingly after satisfactory response is achieved.
Uses: For acute and long-term use in the management of signs and symptoms of osteoarthritis and rheumatoid arthritis
Usual Adult Dose for Pain:
Immediate Release: 200 mg to 400 mg orally every 6 to 8 hours
-Maximum dose: 1000 mg/day
Use: For the management of acute pain
Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:
Extended Release:
6 to 16 years:
20 to 30 kg: 400 mg orally once a day
31 to 45 kg: 600 mg orally once a day
40 to 60 kg: 480 mg orally once a day
Greater than 60 kg: 1000 mg orally once a day
17 to 18 years: 400 mg to 1000 mg orally once a day
Use: For the relief of signs and symptoms of juvenile rheumatoid arthritis
 Detailed Etodolac dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include drowsiness, vomiting, stomach pain, or stomach bleeding.
