Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Gavreto may affect the way other medicines work, and other medicines may affect how Gavreto works.
Before taking this medicine
To make sure Gavreto is safe for you, tell your doctor if you have ever had::
lung or breathing problems other than lung cancer;
bleeding problems; or
high blood pressure.
Pralsetinib can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, do not use Gavreto if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective non-hormonal birth control to prevent pregnancy while you are using this medicine and for at least 2 weeks after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 1 week after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Gavreto.
Gavreto can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using Gavreto, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Gavreto is not approved for use by anyone younger than 18 years old.
How should I take Gavreto?
Take Gavreto exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Take Gavreto on an empty stomach, at least 1 hour before or 2 hours after a meal.
If you vomit shortly after taking Gavreto, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Your blood pressure will need to be checked often and you will need frequent blood tests.
If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.
Do not change your dose or stop using a medicine without your doctor's advice.
Store at room temperature away from moisture and heat.
