Stop using Soliqua and call your doctor at once if you have nausea and vomiting with severe pain in your upper stomach spreading to your back.
Never share an injection pen or syringe with another person, even if the needle has been changed.
Before taking this medicine
You should not use Soliqua is safe for you, tell your doctor if you have every had:if you are allergic to insulin or lixisenatide, or if:
you are having an episode of low blood sugar;
you also use a short-acting mealtime insulin; or
you also use lixisenatide (Adlyxin) or a medicine like lixisenatide (albiglutide, dulaglutide, exenatide, liraglutide, Byetta, Bydureon, Saxenda, Tanzeum, Trulicity, Victoza).
To make sure Soliqua is safe for you, tell your doctor if you have every had:
pancreatitis or gallstones;
alcoholism;
problems digesting food;
heart failure;
liver or kidney disease;
low levels of potassium in your blood (hypokalemia); or
diabetic ketoacidosis (call your doctor for treatment).
Tell your doctor if you are pregnant or breastfeeding.
Follow your doctor's instructions about using Soliqua 100/33 if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high sugar may cause complications in both the mother and the baby.
How should I use Soliqua 100/33?
Use Soliqua 100/33 exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Do not use more than 60 units of Soliqua 100/33 each day.
Soliqua is injected under the skin, usually within 1 hour before your first meal of the day. A healthcare provider will teach you how to properly use the medication by yourself.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.
Do not inject Soliqua into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.
You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).
Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. Becoming dehydrated while using Soliqua can lead to kidney failure. Drink plenty of water each day.
Storing the unopened (not in use) Soliqua 100/33 injection pen: Refrigerate and protect from light.
Do not freeze Soliqua, and throw away the medicine if it has been frozen.
Storing the opened (in use) injection pen: Store at room temperature with the pen cap attached (but not with a needle attached), and use within 28 days.
Never share a Soliqua 100/33 injection pen, cartridge, or syringe with another person, even if the needle has been changed. Sharing these devices can allow infections or disease to pass from one person to another.
