Get emergency medical help if you have signs of an allergic reaction to Orencia: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, light-headed, itchy, or have a severe headache or trouble breathing within 1 hour after receiving the injection.
You may get infections more easily, even serious or fatal infections. Call your doctor right away if you have signs of infection such as:
fever, chills, night sweats, flu symptoms, weight loss;
feeling very tired;
dry cough, sore throat; or
warmth, pain, or redness of your skin.
Call your doctor at once if you have any of these other serious side effects:
trouble breathing;
stabbing chest pain, wheezing, cough with yellow or green mucus;
pain or burning when you urinate; or
signs of skin infection such as itching, swelling, warmth, redness, or oozing.
Common Orencia side effects may include:
fever;
nausea, diarrhea, stomach pain;
headache; or
cold symptoms such as stuffy nose, sneezing, sore throat, cough.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Orencia side effects (more detail)
