Taking  metolazone with other drugs that make you make you light-headed can worsen this effect. Ask your doctor before taking metolazone with a narcotic pain medicine, muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your current medicines and any you start or stop using, especially:
any other blood pressure medication;
digoxin, digitalis;
furosemide or other diuretics (water pills);
insulin or oral diabetes medicine;
lithium;
methenamine;
vitamin D (at high doses);
a blood thinner--warfarin, Coumadin, Jantoven;
NSAIDs (nonsteroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
salicylates--aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others; or
steroid medicine--prednisone and others.
This list is not complete. Other drugs may interact with metolazone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
 Metolazone drug interactions (more detail)
Does Metolazone interact with my other drugs?
Enter other medications to view a detailed report.
Drug name
Add a drug to check interactions
Add
