Your symptoms may become temporarily worse when you first start using Lupron Depot. Tell your doctor if this continues for longer than 2 months.
Call your doctor at once if you have a seizure, or unusual changes in mood or behavior.
Lupron Depot can harm an unborn baby or cause birth defects. Do not use if you are pregnant or breastfeeding.
Before taking this medicine
You should not use Lupron Depot if you are allergic to leuprolide or similar medicines such as buserelin, goserelin, histrelin, nafarelin, or if you have abnormal vaginal bleeding that has not been checked by a doctor.
Lupron Depot can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant.
Certain brands or strengths of leuprolide are used to treat only men and should not be used in women or children. Always check your medicine to make sure you have received the correct brand and strength. Ask the pharmacist if you have any questions about the medicine you receive at the pharmacy.
To make sure Lupron Depot is safe for you, tell your doctor if you have ever had:
depression, mental illness or psychosis;
seizures or epilepsy;
a blood vessel disorder;
a brain tumor or spinal cord injury;
heart disease, congestive heart failure, long QT syndrome;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
risk factors for bone loss (personal or family history of osteoporosis, smoking, alcohol use, taking steroid or seizure medicines long term).
Do not give this medicine to any child without medical advice.
Lupron Depot usually causes women to stop ovulating or having menstrual periods. However, you may still be able to get pregnant. Use a condom or diaphragm with spermicide to prevent pregnancy. Lupron Depot can make hormonal birth control less effective (birth control pills, injections, implants, skin patches, vaginal rings).
Call your doctor if your periods continue while you are being treated with this medicine.
You should not breast-feed while using Lupron Depot.
How should I use Lupron Depot?
Use Lupron Depot exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Different brands or strengths of leuprolide are used to treat different conditions. It is very important that you receive exactly the brand and strength your doctor has prescribed. Always check your medication to make sure you have received the correct brand and type prescribed by your doctor.
Lupron Depot is injected under the skin or into a muscle, once every month or once every 3 to 6 months. A healthcare provider can teach you how to properly use the medication by yourself.
Read and carefully follow any Instructions for Use provided with your medicine. Do not use Lupron Depot if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.
Your symptoms may become temporarily worse as your hormones adjust to leuprolide.
Keep using the medicine as directed, and tell your doctor if your condition is still worse after 2 months of using Lupron Depot.
You may need frequent medical tests while using Lupron Depot.
Store Lupron Depot in the original carton at room temperature, away from moisture and heat. Protect from light.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
