Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Chlorthalidone treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen.
Chlorthalidone is also used to treat high blood pressure (hypertension).
Chlorthalidone may also be used for purposes not listed in this medication guide.
