Verzenio can cause severe severe diarrhea, which can lead to dehydration or infection. Call your doctor right away if you have diarrhea. Drink extra fluids and start taking anti-diarrhea medicine such as loperamide (Imodium).
Verzenio can cause blood clots, liver problems, or serious and sometimes fatal infections. Call your doctor right away if you have symptoms such as: fever, chills, easy bruising or bleeding, unusual tiredness, loss of appetite, right-sided upper stomach pain, chest pain, shortness of breath, rapid breathing, fast heartbeats, or pain or swelling in your arms or legs.
Before taking this medicine
You should not use Verzenio if you are allergic to abemaciclib.
To make sure Verzenio is safe for you, tell your doctor if you have ever had:
a fever, chills, or other signs of infection; or
liver or kidney disease.
You may need to have a negative pregnancy test before starting this treatment.
Using Verzenio during pregnancy could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 weeks after your treatment ends. Tell your doctor right away if you become pregnant during this time.
You should not breastfeed while using this medicine and for at least 3 weeks after your last dose.
How should I take abemaciclib?
Take Verzenio exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Take the medicine at the same time each day, with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
If you vomit shortly after taking Verzenio, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Drink plenty of liquids while you are taking Verzenio.
Abemaciclib can cause severe diarrhea, which can be life-threatening if it leads to dehydration or infection.
If you have diarrhea while taking Verzenio: start taking anti-diarrhea medicine such as loperamide (Imodium) to quickly treat diarrhea. Drink extra fluids and call your doctor.
Abemaciclib can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.
Store at room temperature away from moisture and heat.
