Get emergency medical help if you have signs of an allergic reaction to Dupixent: hives, rash, itching; fever, swollen glands, joint pain; feeling light-headed, difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
new or worsening eye pain or discomfort;
vision changes;
watery eyes (your eyes may be more sensitive to light);
feeling like something is in your eye; or
blood vessel inflammation--fever, chest pain, trouble breathing, skin rash, numbness or prickly feeling in your arms or legs.
Common Dupixent side effects may include:
pain, swelling, burning, or irritation where an injection was given;
blood vessel inflammation;
eye redness or itching, puffy eyelids;
stomach pain, nausea, vomiting;
sore throat;
tooth pain;
sleep problems (insomnia);
joint pain; or
cold sores or fever blisters on your lips or in your mouth.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Dupixent side effects (more detail)
