Nerlynx can cause severe diarrhea, which can be life-threatening if it leads to dehydration. You may be given anti-diarrhea medications for the first 2 months of treatment with Nerlynx.
Call your doctor if you are sick with severe diarrhea, or you also have weakness, dizziness, or a fever.
Before taking this medicine
To make sure Nerlynx is safe for you, tell your doctor if you have ever had:
liver disease.
You may need to have a negative pregnancy test before starting this treatment.
Neratinib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
If you are a woman, do not use Nerlynx if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 1 month after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Nerlynx.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
How should I take Nerlynx?
Take Nerlynx exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
The usual dose of Nerlynx is 6 tablets taken once daily. Take the medicine with food, at the same time each day.
You may need to take this medicine daily for up to one year. Nerlynx is sometimes taken daily in 21-day treatment cycles until the medicine stops working or until you have serious side effects.
Your doctor will determine how long to treat you with this medicine. Follow your doctor's dosing instructions very carefully.
Swallow the tablet whole and do not crush, chew, or break it.
Nerlynx can cause severe diarrhea, which can be life-threatening if it leads to dehydration. For the first 2 months of treatment with Nerlynx, you may need to take medication to prevent or quickly treat diarrhea.
Your doctor may recommend you have an anti-diarrhea medicine such as loperamide (Imodium) available at all times while you are taking Nerlynx. Take the anti-diarrhea medicine exactly as prescribed by your doctor.
To best control diarrhea, you may need to follow a special diet. Get familiar with the list of foods you should eat or avoid to help control diarrhea. You may also need to drink extra fluids to keep from getting dehydrated.
Tell your doctor if you have more than 2 bowel movements in 1 day.
Call your doctor if you are sick with severe diarrhea, or you also have weakness, dizziness, or a fever. You may need to stop taking this medicine for a short time.
You may need frequent blood tests.
Store at room temperature away from moisture and heat.
