Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
weakness, confusion, or a light-headed feeling (like you might pass out);
irregular heartbeats;
unexplained weight loss;
dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or
liver problems--right-sided upper stomach pain, vomiting, loss of appetite, fever, itching, yellowing of your skin or eyes, not feeling well.
Samsca is given to treat low levels of sodium in your blood, but can be dangerous if your sodium level rises too fast. Tell your doctor or caregivers at once if you have any of these signs that your hyponatremia is being reversed too quickly:
problems with speech or muscle control;
trouble swallowing;
trouble moving your arms and legs;
confusion, mood changes; or
a seizure.
Common side effects may include:
dry mouth;
increased thirst or urination;
hunger, fruity breath odor;
constipation; or
weakness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Jynarque side effects (more detail)
