Usual Adult Dose for Osteolytic Bone Lesions of Multiple Myeloma:
Zometa: 4 mg IV over no less than 15 minutes, every 3 to 4 weeks.
Comments: Oral calcium supplement of 500 mg and a multiple vitamin containing 400 international units of vitamin D daily are recommended.
Uses: Patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy.
Usual Adult Dose for Osteolytic Bone Metastases of Solid Tumors:
Zometa: 4 mg IV over no less than 15 minutes, every 3 to 4 weeks.
Comments: Oral calcium supplement of 500 mg and a multiple vitamin containing 400 international units of vitamin D daily are recommended.
Uses: Patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy.
Usual Adult Dose for Hypercalcemia of Malignancy:
Zometa: Maximum dose: Single dose of 4 mg IV infusion over no less than 15 minutes.
Comments: If serum calcium does not return to normal, retreatment should be considered after a minimum of 7 elapsed days.
Use: Treatment of hypercalcemia of malignancy (albumin-corrected calcium equal 12 mg/dL or greater).
 Detailed Zometa dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Zometa injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
