Taking midodrine with other drugs that constrict blood vessels can further increase your blood pressure. Tell your doctor about all your current medicines and any you start or stop using, especially:
digoxin, digitalis, droxidopa, fludrocortisone
an antidepressant;
asthma medicine;
heart or blood pressure medicine;
migraine headache medicine;
thyroid medicine such as levothyroid or Synthroid;
drugs to treat high blood pressure or a prostate disorder--prazosin, terazosin, or doxazosin; or
an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine.
This list is not complete. Other drugs may interact with midodrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
 Midodrine drug interactions (more detail)
