Skyrizi affects your immune system. You may get infections more easily. Call your doctor if you have symptoms such as fever, chills, cough, trouble breathing, diarrhea, burning when you urinate, weight loss, or skin sores on your body (different from psoriasis).
Before taking this medicine
Before you start treatment with Skyrizi, your doctor may perform tests to make sure you do not have tuberculosis or other infections.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.
Tell your doctor if you currently have signs of infection such as fever, chills, muscle pain, cough, trouble breathing, skin sores, stomach pain, diarrhea, weight loss, or painful urination.
Make sure you are current on all vaccines before you begin treatment with Skyrizi.
Tell your doctor if you are pregnant or breastfeeding.
Skyrizi is not approved for use by anyone younger than 18 years old.
How should I use Skyrizi?
Skyrizi is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Read and carefully follow any Instructions for Use provided with your medicine. You may need to use 2 injections to get your total dose. Ask your doctor or pharmacist if you don't understand all instructions.
Skyrizi should be clear or light-yellow. Do not use if the medicine looks cloudy, has changed colors, or has flakes or large particles in it. Call your pharmacist for new medicine.
Your care provider will show you where on your body to inject Skyrizi. Do not inject into skin with active psoriasis, or skin that is red, bruised, or tender. Do not inject within 2 inches of your navel (belly button).
Skyrizi affects your immune system. You may get infections more easily. Your doctor will need to examine you on a regular basis.
Store Skyrizi in the original container in a refrigerator. Protect from light and do not shake or freeze. Take the medicine out of the refrigerator and allow it to reach room temperature for 15 to 30 minutes before injecting your dose. Do not heat the medicine in a microwave or with hot water.
Each prefilled Skyrizi syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
