Ibrutinib can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop.
Bleeding may also happen inside your body. Call your doctor at once if you have signs such as dizziness, confusion, headache, speech problems, black or bloody stools, pink or brown urine, or coughing up blood or vomit that looks like coffee grounds.
Ibrutinib also affects your immune system. You may get infections more easily, even serious or fatal infections. Tell your doctor if you have a fever, chills, cough, mouth sores, or other signs of infection.
Before taking this medicine
You should not use ibrutinib if you are allergic to it.
Tell your doctor if you have ever had:
an infection;
liver disease;
bleeding problems;
a heart rhythm disorder; or
risk factors for heart disease (such as diabetes, smoking, being overweight, having high blood pressure or high cholesterol).
Using ibrutinib may increase your risk of developing other types of cancer. Ask your doctor about your specific risk.
Both men and women using  ibrutinib should use birth control to prevent pregnancy. Ibrutinib can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ibrutinib .
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
