Usual Adult Dose of Tysabri for Multiple Sclerosis:
300 mg IV over 1 hour once every 4 weeks
Comments:
-Only prescribers registered in the MS TOUCH (R) Prescribing Program may prescribe this drug for multiple sclerosis.
-Patients should be observed during the infusion and for one hour after the infusion is complete.
Use: Multiple Sclerosis (MS): As monotherapy for the treatment of patients with relapsing forms of multiple sclerosis
Usual Adult Dose of Tysabri for Crohn's Disease - Maintenance:
300 mg IV over 1 hour once every 4 weeks
Comments:
-Only prescribers registered in the CD TOUCH (R) Prescribing Program may prescribe this drug for Crohn's disease.
-This drug should not be used with concomitant immunosuppressants (e.g., 6-mercaptopurine, azathioprine, cyclosporine, methotrexate) or concomitant inhibitors of TNF-alpha.
-Aminosalicylates may be continued during treatment with this drug.
-If the patient has not experienced therapeutic benefit by 12 weeks of induction therapy, this drug should be discontinued.
-For patients who start this drug while on chronic oral corticosteroids, steroid tapering should commence as soon as a therapeutic benefit of this drug has occurred; if the patient cannot be tapered off of oral corticosteroids within 6 months of starting this drug, then this drug should be discontinued.
-Other than the initial 6 month taper, prescribers should consider discontinuing this drug for patients who require additional steroid use that exceeds 3 months in a calendar year to control their Crohn's disease.
-Patients should be observed during the infusion and for one hour after the infusion is complete.
Use: Crohn's Disease (CD): For inducing and maintaining clinical response and remission in adult patients with moderately to severely active Crohn's disease with evidence of inflammation who have had an inadequate response to, or are unable to tolerate conventional CD therapies and inhibitors of TNF-alpha
 Detailed Tysabri dosage information
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Tysabri injection.
What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
