Many other drugs can be dangerous when used with Nucynta. Tell your doctor if you also use:
medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder;
other opioid medicines;
a benzodiazepine sedative like Valium, Klonopin, or Xanax;
sleep medicine, muscle relaxers, or other drugs that make you drowsy; or
drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease.
This list is not complete. Many drugs may interact with tapentadol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
 Nucynta drug interactions (more detail)
