Usual Adult Dose for Hypertension:
-Initial dose: 25 mg orally once a day-Titration: Increase to 50 mg orally once a day if response is inadequate; if response is still inadequate, increase to 100 mg orally once a day, or a second antihypertensive drug (step 2 therapy) may be added-Maintenance dose: 25 to 100 mg orally once a day-Maximum dose: 100 mg orally once a dayComments:-Doses should be taken in the morning with food.-Maintenance doses may be lower than initial doses and should be adjusted according to individual patient response.  -Effectiveness is well sustained during continued use.Use: Hypertension (alone or with another antihypertensive drug)
Usual Adult Dose for Edema:
-Initial dose: 50 to 100 mg orally once a day, or 100 mg orally every other day; some patients may require 150 to 200 mg orally at these intervals-Maximum dose: 200 mg orally once a dayComments:-Doses should be taken in the morning with food.-Maintenance doses may be lower than initial doses and should be adjusted according to individual patient response.  -Effectiveness is well sustained during continued use.Use: For edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure
 Detailed Chlorthalidone dosage information
