You should not take ranolazine if you have cirrhosis of the liver.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
You should not take ranolazine if you are allergic to it, or if you have:
cirrhosis of the liver.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with ranolazine. Your doctor may change your treatment plan if you also use:
clarithromycin;
nefazodone;
St. John's wort;
antifungal medicine--itraconazole, ketoconazole;
HIV or AIDS medicine--indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir;
seizure medicine--carbamazepine, phenobarbital, phenytoin; or
tuberculosis medicine--rifabutin, rifampin, rifapentine.
Tell your doctor if you have ever had:
long QT syndrome (in you or a family member);
liver disease; or
kidney disease.
Tell your doctor if you are pregnant or breastfeeding.
How should I take ranolazine?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take ranolazine with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
Chronic angina is often treated with a combination of drugs. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice.
Call your doctor if your symptoms do not improve, or if they get worse.
You will need frequent medical tests to check your heart and kidney function.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose can cause nausea, vomiting, numbness or tingling, dizziness, double vision, confusion, or fainting.
