You should not use Toradol if you have any active or recent bleeding (including bleeding inside your body), a head injury, a stomach ulcer, severe kidney disease, a bleeding or blood-clotting disorder, a history of severe allergic reaction to aspirin or an NSAID, or if you are scheduled to have surgery.
Do not use Toradol if you are in your third trimester of pregnancy or if you are breast-feeding a baby.
You should not use ketorolac if you also take pentoxifylline, probenecid, aspirin, or other NSAID drugs (which may include ibuprofen, acetaminophen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, and others and others).
Ketorolac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.
Do not drink alcohol while taking Toradol. Alcohol can increase the risk of stomach bleeding caused by ketorolac.
Before taking this medicine
Toradol can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
You should not use Toradol if you are allergic to ketorolac, or if you have:
active or recent stomach ulcer, stomach bleeding, or intestinal bleeding;
a bleeding or blood-clotting disorder;
a closed head injury or bleeding in your brain;
bleeding from a recent surgery;
severe kidney disease or dehydration;
a history of asthma or severe allergic reaction after taking aspirin or an NSAID;
if you are scheduled to have surgery (especially bypass surgery); or
if you are in late pregnancy or you are breast-feeding a baby.
Some medicines can cause unwanted or dangerous effects when used with ketorolac. Your doctor may need to change your treatment plan if you use any of the following drugs:
pentoxifylline;
probenecid; or
aspirin or other NSAIDs - ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
To make sure Toradol is safe for you, tell your doctor if you have ever had:
heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;
a heart attack, stroke, or blood clot;
stomach ulcers or bleeding;
inflammatory bowel disease, ulcerative colitis, or Crohn's disease;
liver disease;
kidney disease (or if you are on dialysis);
asthma; or
fluid retention.
If you are pregnant, you should not take ketorolac unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.
Tell your doctor if you are breastfeeding.
Toradol is not approved for use by anyone younger than 2 years old.
