Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
For adults
Less common
Fast or irregular heartbeat
Rare
Bone, muscle, or joint pain
fainting
fast or irregular breathing
numbness or tingling of the hands or feet
puffiness or swelling of the eyelids or around the eyes
skin rash, hives, or itching
sudden, severe decrease in blood pressure and collapse
tightness in the chest
trouble breathing
For males only (adults)
More common
Arm, back, or jaw pain
bloody or cloudy urine
blurred vision
chest pain or discomfort
difficult, burning, or painful urination
difficulty with moving
dizziness
frequent urge to urinate
headache
increased urge to urinate during the night
muscle pain or stiffness
nausea
nervousness
pain in the joints
pale skin
pounding in the ears
slow or fast heartbeat
sweating
unusual bleeding or bruising
unusual tiredness or weakness
waking to urinate at night
Rare
Pain in the groin or legs (especially in the calves)
Incidence not known
Altered mental status
cold, clammy, pale skin
confusion
double vision
irregular heartbeat
visual changes
vomiting
For females only (adults)
Rare
Anxiety
deepening of voice
increased hair growth
mental depression
mood changes
For children
More common
Body aches or pain
chills
cough
cough producing mucus
difficulty in breathing
ear congestion
fever
headache
loss of voice
muscle aches
noisy breathing
pain or redness at the injection site
runny or stuffy nose
sneezing
sore throat
tightness in the chest
unusual tiredness or weakness
Less common
Irritability
mood or mental changes
Rare
Burning, itching, or swelling at the injection site
Incidence not known
Seizures
For females only (children)—expected in first few weeks
Rare
Vaginal bleeding (continuing)
white vaginal discharge (continuing)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For adults
More common
Sudden sweating and feeling of warmth (hot flashes)
Less common
Bleeding, bruising, burning, itching, pain, redness, or swelling at the injection site
decreased interest in sexual intercourse
swelling of the feet or lower legs
swelling or increased tenderness of the breasts
trouble sleeping
weight gain
For females only (adults)
More common
Light, irregular vaginal bleeding
stopping of menstrual periods
Less common
Burning, dryness, or itching of the vagina
pelvic pain
For males only (adults)
More common
Back pain
chills
constipation
cough
diarrhea
fever
general feeling of discomfort or illness
loss of appetite
pain or discomfort at the injection site
redness of the face, neck, arms, and occasionally, upper chest
runny nose
shivering
sore throat
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Less common
Decreased size of the testicles
inability to have or keep an erection
For children
More common
Constipation
feeling of warmth
nausea
redness of the face, neck, arms and occasionally, upper chest
stomach pain
vomiting
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
 Lupron side effects (more detail)
