Get emergency medical help if you have signs of an allergic reaction to Percocet: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen or Tylenol in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Oxycodone can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
noisy breathing, sighing, shallow breathing, breathing that stops during sleep;
slow heartbeat or week pulse;
cold, clammy skin;
a light-headed feeling, like you might pass out;
weakness, tiredness, fever, unusual bruising or bleeding;
confusion, unusual thoughts or behavior;
seizure (convulsions);
problems with urination;
signs of liver problems including nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
high levels of serotonin in the body - agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.
Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.
Common Percocet side effects include:
dizziness, drowsiness, feeling tired;
headache;
constipation, nausea, vomiting, stomach pain;
blurred vision;
itching, red eyes, or flushing;
feelings of extreme happiness or sadness; or
dry mouth
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Percocet side effects (more detail)
