You should not use glycopyrrolate if you have urination problems, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, myasthenia gravis, or active bleeding with heart and blood circulation problems.
Before taking this medicine
You should not use glycopyrrolate if you are allergic to it, or if you have:
a bladder obstruction or other urination problems;
a stomach or bowel obstruction (including paralytic ileus);
severe constipation;
severe ulcerative colitis or toxic megacolon;
glaucoma;
myasthenia gravis; or
active bleeding with fast heartbeats, low blood pressure, shortness of breath, and cold hands or feet.
Tell your doctor if you have ever had:
an enlarged prostate;
liver or kidney disease;
heart problems or a heart rhythm disorder;
high blood pressure;
a stomach disorder such as ulcerative colitis, hiatal hernia, reflux disease, or slow digestion;
a colostomy or ileostomy;
a thyroid disorder; or
a nerve disorder.
It is not known whether  glycopyrrolate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using glycopyrrolate. Glycopyrrolate may slow breast milk production.
Do not give this medicine to a child without medical advice.
