Some drugs can make norethindrone less effective, which may result in unintended pregnancy if you use  norethindrone for contraception. Tell your doctor about all your other medicines, especially:
St. John's wort;
medicine to treat an infection (antibiotics or antifungal medicine);
medicine to treat tuberculosis;
medicine to treat HIV or AIDS; or
seizure medication.
This list is not complete. Other drugs may affect norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
 Norethindrone drug interactions (more detail)
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