Usual Adult Dose of Repatha for Hyperlipidemia:
-140 mg subcutaneously every 2 weeks, or
-420 mg subcutaneously once a month
Comments:
-When switching dosage regimens, administer the first dose of the new regimen on the next scheduled date of prior regimen.
-This drug should not be used in patients without familial hypercholesterolemia or atherosclerotic cardio vascular disease.
Uses: Adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease requiring additional lowering of low density lipoprotein cholesterol (LDL-C)
Usual Adult Dose of Repatha for Homozygous Familial Hypercholesterolemia:
-420 mg subcutaneously once a month
Comments:
-Measure LDL-C levels every 4 to 8 weeks after starting this drug.
-Response to therapy depends on the degree of LDL-receptor function.
Uses: Adjunct to diet and other LDL-lowering therapies (e.g., statins, ezetimibe, LDL apheresis) for the treatment of patients with homozygous familial hypercholesterolemia (HoFH) requiring additional lowering of LDL-C
 Detailed Repatha dosage information
What happens if I miss a dose?
Use the missed dose within 7 days after that injection was due. Skip the missed dose if you are more than 7 days late for the injection. After a missed dose, go back to your original schedule and use the medicine again when your next scheduled dose is due.
Do not use extra medicine to make up a missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
