You should not use Zoloft if you also take pimozide, or if you are being treated with methylene blue injection.
Do not use Zoloft if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Before taking this medicine
You should not use Zoloft if you are allergic to sertraline, or if you also take pimozide. Do not use Zoloft oral solution if you take disulfiram (Antabuse).
Do not use Zoloft within 14 days before or 14 days after using an MAO inhibitor. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with sertraline could cause a serious condition called serotonin syndrome.
To make sure Zoloft is safe for you, tell your doctor if you have ever had:
bipolar disorder (manic depression);
heart disease, high blood pressure, or a stroke;
liver or kidney disease;
seizures;
glaucoma;
bleeding problems, or if you take warfarin (Coumadin, Jantoven);
long QT syndrome; or
low levels of sodium in your blood.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Zoloft is approved for use in children at least 6 years old, only to treat obsessive-compulsive disorder but not depression.
Taking this medicine during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop Zoloft without asking your doctor.
Ask a doctor if it is safe to breastfeed while using Zoloft .
How should I take Zoloft?
Take Zoloft exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Take Zoloft with or without food, at the same time each day.
Zoloft liquid (oral concentrate) must be diluted with a liquid right before you take it. Read and carefully follow all mixing instructions provided with your medicine. Ask your doctor or pharmacist if you need help.
Measure the mixed medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).
Sertraline may cause false results on a drug-screening urine test. Tell the laboratory staff that you use Zoloft.
Do not stop using Zoloft suddenly, or you could have unpleasant symptoms (such as agitation, confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine.
Store tightly closed at room temperature, away from moisture and heat.
