Do not use this medicine if you are pregnant or think you might be pregnant.
You should not use this medicine if you have: uncontrolled high blood pressure, heart problems, coronary artery disease, health problems caused by diabetes, undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches (especially if you are older than 35), if you have a BMI of 30 or higher, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.
Using hormonal birth control can increase your risk of blood clots, stroke, or heart attack.
Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not use this medicine if you smoke and are older than 35 years of age.
Before taking this medicine
Using hormonal birth control can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of using birth control. Your risk is also high when you restart this medicine after not using for 4 weeks or longer.
Smoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not use this medicine if you smoke and are over 35 years old.
Your risk of serious blood clot may be higher with the use of birth control skin patches than with the use of birth control pills.
Do not use if you are pregnant, if you become pregnant, or if you've had a baby in the past 4 weeks.
You should not use hormonal birth control if you have:
untreated or uncontrolled high blood pressure;
heart problems (chest pain, coronary artery disease, history of heart attack, stroke, or blood clot);
an increased risk of having blood clots due to a hereditary blood disorder;
health problems caused by diabetes (such as damage to your kidneys, eyes, nerves, or blood vessels);
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;
unusual vaginal bleeding that has not been checked by a doctor;
liver disease or liver cancer;
severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;
if you are overweight and have a BMI (body mass index) of 30 or higher; or
if you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir (Viekira).
Tell your doctor if you have ever had:
heart problems, high blood pressure, or if you are prone to having blood clots;
depression;
migraine headaches;
liver disease;
jaundice caused by pregnancy or birth control pills; or
diabetes, gallbladder disease, underactive thyroid.
This medicine may not be as effective if you weigh more than 198 pounds (90 kilograms). If you are overweight, your doctor may recommend another form of birth control for you.
This medicine can slow breast milk production. You should not breastfeed while using  Xulane.
