You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide dinitrate. Taking these medicine together can cause a sudden and serious decrease in blood pressure.
Seek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, sweating, general ill feeling).
Before taking this medicine
You should not use isosorbide dinitrate if:
you are allergic to isosorbide dinitrate, isosorbide mononitrate, or nitroglycerin; or
you have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating).
You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide dinitrate. Taking these medicines together can cause a sudden and serious decrease in blood pressure.
To make sure isosorbide dinitrate is safe for you, tell your doctor if you have:
congestive heart failure;
kidney disease; or
low blood pressure.
It is not known whether  isosorbide dinitrate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether isosorbide dinitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.
