Usual Adult Dose for Edema:
Usual dose: 25 mg to 100 mg orally once or twice daily
Comments:
-Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Excessive response and undesirable electrolyte imbalance are less likely to occur with intermittent dosing.
Usual Adult Dose for Hypertension:
Initial dose: 25 mg orally once daily
Maintenance dose: May increase to 50 mg orally daily, as a single or 2 divided doses
Comments:
-Patients usually do not require doses in excess of 50 mg daily when used concomitantly with other antihypertensive agents.
Usual Adult Dose for Nephrocalcinosis:
Initial: 25 mg orally once daily
Maintenance dose: May increase to 50 mg twice daily
Usual Adult Dose for Osteoporosis:
Initial: 25 mg orally once daily
Maintenance dose: May increase to 50 mg daily
Usual Adult Dose for Diabetes Insipidus:
Initial: 50 mg orally once daily
Maintenance dose: May increase to 100 mg orally daily
Usual Pediatric Dose for Edema:
Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses
Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 37.5 mg per day
2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 100 mg per day
Usual Pediatric Dose for Hypertension:
Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses
Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 37.5 mg per day
2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses
Maximum dose 100 mg per day
 Detailed Hydrochlorothiazide dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, dizziness, dry mouth, thirst, and muscle pain or weakness.
