Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody;
sudden pain or trouble moving your hip, wrist, or back;
seizure (convulsions);
kidney problems--fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, swelling, rapid weight gain;
new or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight;
low magnesium--dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or
signs of bleeding (if you also take warfarin)--headaches, dizziness, weakness; pain or swelling; bruising, unusual bleeding (nosebleeds, bleeding gums); red or pink urine; heavy menstrual flow; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or any bleeding that will not stop.
Taking rabeprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.
If you use rabeprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.
Common side effects may include:
infection;
pain;
sore throat;
headache;
nausea, vomiting;
gas, diarrhea, constipation; or
stomach pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
 Rabeprazole side effects (more detail)
