Serious and sometimes fatal reactions may occur during treatment with Yervoy, or months after stopping. Call your doctor at once if you have: chest pain, cough, shortness of breath, vision changes, severe muscle pain or weakness, diarrhea and severe stomach pain, blood in your stools, little or no urinating, swelling, bruising or bleeding, dark urine, yellowing of the skin or eyes, confusion, hallucinations, a seizure, skin blistering, or a hormonal disorder (frequent headaches, feeling light-headed, increased thirst or urination, feeling cold, weight gain or loss).
Before you receive Yervoy, tell your doctor if you have liver damage, an autoimmune disorder such as lupus or sarcoidosis, Crohn's disease, ulcerative colitis, or if you have received an organ transplant.
Tell your doctor if you are pregnant or plan to become pregnant while using Yervoy.
Before taking this medicine
You should not receive Yervoy if you are allergic to ipilimumab.
To make sure Yervoy is safe for you, tell your doctor if you have ever had:
liver problems;
an autoimmune disorder (lupus, sarcoidosis, Crohn's disease, ulcerative colitis); or
an organ transplant or stem cell transplant.
You may need to have a negative pregnancy test before starting this treatment.
Ipilimumab may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of ipilimumab on the baby.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose.
Yervoy is not approved for use by anyone younger than 12 years old. For some types of cancer, Yervoy is used only in adults.
