Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell your doctor about the following medications, which can interact with Lantus:
pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin);
other anti-diabetic medications;
blood pressure medications (including ACE-inhibitors, diuretics or water pills, clonidine, beta-blockers;
birth control pills;
thyroid medications;
anti-depressant medications (especially monoamine oxidase inhibitors or MAOIs, fluoxetine, and others);
anti-psychotic medications (including olanzapine, clozapine, and others);
certain antibiotics, including sulfa drugs; or
corticosteroid medications (such as prednisone);
Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products.
 Lantus drug interactions (more detail)
