{"version": "0.2.0", "data": [{"title": "warnings_inlyta", "paragraphs": [{"qas": [{"question": "How should pregnant women use Inlyta?", "id": 1500, "answers": [{"text": "Do not use Inlyta if you are pregnant. It could harm the unborn baby.", "answer_start": 0}, {"text": "Use birth control to prevent pregnancy while you are receiving this medicine, whether you are a man or a woman", "answer_start": 70}, {"text": "Both men and women using this medicine should use effective birth control to prevent pregnancy.", "answer_start": 1527}], "is_impossible": false}, {"question": "Is bleeding dangerous when i use Inlyta?", "id": 1501, "answers": [{"text": "Stop using Inlyta and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.", "answer_start": 303}, {"text": "Stop using Inlyta and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.", "answer_start": 303}, {"text": "Stop using Inlyta and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.", "answer_start": 303}], "is_impossible": false}, {"question": "How can i control Inlyta effects?", "id": 1502, "answers": [{"text": "To be sure this medication is not causing harmful effects, your kidney, thyroid, and liver function will need to be tested.", "answer_start": 859}, {"text": "Your blood pressure will also need to be checked often. Visit your doctor regularly.", "answer_start": 983}, {"text": "Your blood pressure will also need to be checked often. Visit your doctor regularly.", "answer_start": 983}], "is_impossible": false}, {"question": "What is the usual use of Inlyta?", "id": 1503, "answers": [{"text": "Inlyta is usually taken once every 12 hours. It should be taken at evenly spaced intervals.", "answer_start": 732}, {"text": "Take this medicine with a full glass of water. You may take this medicine with or without food.", "answer_start": 2521}, {"text": "If you vomit shortly after taking Inlyta, do not take another dose. Wait until your next scheduled dose time to take the medicine again.", "answer_start": 2679}], "is_impossible": false}, {"question": "How i make sure Inlyta is safe for me?", "id": 1504, "answers": [{"text": "tell your doctor if you have: a perforation (a hole or tear) in your stomach or intestines; bleeding problems, or a wound that has not healed; a heart attack, heart failure, stroke, or blood clot. high blood pressure; liver disease; or a thyroid disorder.", "answer_start": -1}, {"text": "tell your doctor if you have: a perforation (a hole or tear) in your stomach or intestines; bleeding problems, or a wound that has not healed; a heart attack, heart failure, stroke, or blood clot. high blood pressure; liver disease; or a thyroid disorder.", "answer_start": -1}, {"text": "tell your doctor if you have: a perforation (a hole or tear) in your stomach or intestines; bleeding problems, or a wound that has not healed; a heart attack, heart failure, stroke, or blood clot. high blood pressure; liver disease; or a thyroid disorder.", "answer_start": -1}], "is_impossible": false}], "context": "Do not use Inlyta if you are pregnant. It could harm the unborn baby. Use birth control to prevent pregnancy while you are receiving this medicine, whether you are a man or a woman. Inlyta use by either parent may cause birth defects or miscarriage.\nAxitinib can increase your risk of serious bleeding. Stop using Inlyta and call your doctor at once if you have severe stomach pain, bloody or tarry stools, coughing up blood, or any heavy or unusual bleeding.\nSome people taking this medicine have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nInlyta is usually taken once every 12 hours. It should be taken at evenly spaced intervals. Follow your doctor's instructions.\nTo be sure this medication is not causing harmful effects, your kidney, thyroid, and liver function will need to be tested. Your blood pressure will also need to be checked often. Visit your doctor regularly.\nBefore taking this medicine\nYou should not use Inlyta if you are allergic to axitinib.\nTo make sure Inlyta is safe for you, tell your doctor if you have:\na perforation (a hole or tear) in your stomach or intestines;\nbleeding problems, or a wound that has not healed;\na heart attack, heart failure, stroke, or blood clot.\nhigh blood pressure;\nliver disease; or\na thyroid disorder.\nYou may need to have a negative pregnancy test before starting this treatment.\nBoth men and women using this medicine should use effective birth control to prevent pregnancy. Axitinib can cause harm an unborn baby if the mother or father is using this medicine.\nKeep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Inlyta.\nThis medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because axitinib can harm an unborn baby.\nIt is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 2 weeks after your last dose.\nHow should I take Inlyta?\nTake Inlyta exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.\nInlyta should be taken at evenly spaced intervals, usually once every 12 hours.\nTake this medicine with a full glass of water. You may take this medicine with or without food.\nSwallow the tablet whole and do not crush, chew, or break it.\nIf you vomit shortly after taking Inlyta, do not take another dose. Wait until your next scheduled dose time to take the medicine again.\nYour blood pressure will need to be checked often. You may also need frequent medical tests.\nIf you need surgery, tell your surgeon you currently use Inlyta. You will need to stop using the medicine at least 24 hours before a planned surgery.\nStore at room temperature away from moisture and heat."}]}, {"title": "side-effects_inlyta", "paragraphs": [{"qas": [{"question": "Is abdominal pain dangerous after using Inlyta?", "id": 1505, "answers": [{"text": "Some people taking Inlyta have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines", "answer_start": 156}, {"text": "Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.", "answer_start": 300}, {"text": "Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.", "answer_start": 300}], "is_impossible": false}, {"question": "What is common side effect of Inlyta?", "id": 1506, "answers": [{"text": "nausea, vomiting, diarrhea, constipation; rash, itching, redness, and peeling skin on your hands or feet; feeling weak or tired; increased blood pressure; decreased appetite, weight loss; or hoarse voice", "answer_start": -1}, {"text": "nausea, vomiting, diarrhea, constipation; rash, itching, redness, and peeling skin on your hands or feet; feeling weak or tired; increased blood pressure; decreased appetite, weight loss; or hoarse voice", "answer_start": -1}, {"text": "nausea, vomiting, diarrhea, constipation; rash, itching, redness, and peeling skin on your hands or feet; feeling weak or tired; increased blood pressure; decreased appetite, weight loss; or hoarse voice", "answer_start": -1}], "is_impossible": false}], "context": "Get emergency medical help if you have signs of an allergic reaction to Inlyta: hives; difficult breathing; swelling of your face, lips, tongue, or throat.\nSome people taking Inlyta have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.\nAlso call your doctor at once if you have:\nchest pain or pressure, pain spreading to your jaw or shoulder, trouble breathing;\nsudden numbness or weakness, problems with vision or speech;\nheadache, confusion, thinking problems, seizure (convulsions);\na light-headed feeling, like you might pass out;\neasy bruising, unusual bleeding, purple or red spots under your skin;\nheavy menstrual bleeding;\nany bleeding that will not stop;\npink or brown urine;\nheart problems - swelling, rapid weight gain, feeling short of breath;\nsigns of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or\nsigns of a thyroid problem - sudden weight gain or loss, feeling very weak or tired, muscle pain, feeling hot or cold, hair loss, hoarse or deepened voice.\nCommon Inlyta side effects may include:\nnausea, vomiting, diarrhea, constipation;\nrash, itching, redness, and peeling skin on your hands or feet;\nfeeling weak or tired;\nincreased blood pressure;\ndecreased appetite, weight loss; or\nhoarse voice.\nThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.\nInlyta side effects (more detail)"}]}, {"title": "side-effects_fosinopril", "paragraphs": [{"qas": [{"question": "What should pregnant women know about Fosinopril?", "id": 1507, "answers": [{"text": "Fosinopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.", "answer_start": 1166}, {"text": "Do not use if you are pregnant. If you become pregnant, stop taking fosinopril and tell your doctor right away.", "answer_start": 0}, {"text": "Do not use if you are pregnant. If you become pregnant, stop taking fosinopril and tell your doctor right away.", "answer_start": 0}], "is_impossible": false}, {"question": "What is the contraindication for Fosinopril with other medicines?", "id": 1508, "answers": [{"text": "You should not use this medicine if you are allergic to fosinopril or similar medications, such as benazepril, captopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril", "answer_start": 269}, {"text": "You should not use this medicine if you are allergic to fosinopril or similar medications, such as benazepril, captopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril", "answer_start": 269}, {"text": "You should not use this medicine if you are allergic to fosinopril or similar medications, such as benazepril, captopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril", "answer_start": 269}], "is_impossible": false}, {"question": "Can Fosinopril be used with other diseases?", "id": 1509, "answers": [{"text": "To make sure fosinopril is safe for you, tell your doctor if you have: kidney disease (or if you are on dialysis); cirrhosis or other liver disease; a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis; if you are on a low-salt diet; or if you have ever had a severe allergic reaction", "answer_start": -1}, {"text": "You should not use this medicine if you are allergic to fosinopril or similar medications, such as benazepril, captopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.", "answer_start": 269}, {"text": "If you have diabetes, do not use fosinopril together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).", "answer_start": 476}], "is_impossible": false}, {"question": "What is minimum age for use Fosinopril?", "id": 1510, "answers": [{"text": "Do not give this medication to a child younger than 6 years old.", "answer_start": 1406}, {"text": "Do not give this medication to a child younger than 6 years old.", "answer_start": 1406}, {"text": "Do not give this medication to a child younger than 6 years old.", "answer_start": 1406}], "is_impossible": false}, {"question": "What should we pay attention to when using Fosinopril?", "id": 1511, "answers": [{"text": "Your blood pressure will need to be checked often", "answer_start": 2051}, {"text": "Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual.", "answer_start": 1727}, {"text": "You can easily become dehydrated while taking fosinopril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.", "answer_start": 1826}], "is_impossible": false}, {"question": "What should I tell my doctor about Fosinopril?", "id": 1512, "answers": [{"text": "If you need surgery or medical tests, tell the doctor ahead of time that you are using fosinopril.", "answer_start": 2102}, {"text": "If you need surgery or medical tests, tell the doctor ahead of time that you are using fosinopril.", "answer_start": 2102}, {"text": "If you need surgery or medical tests, tell the doctor ahead of time that you are using fosinopril.", "answer_start": 2102}], "is_impossible": false}], "context": "Do not use if you are pregnant. If you become pregnant, stop taking fosinopril and tell your doctor right away.\nIf you have diabetes, do not use fosinopril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).\nBefore taking this medicine\nYou should not use this medicine if you are allergic to fosinopril or similar medications, such as benazepril, captopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.\nIf you have diabetes, do not use fosinopril together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).\nYou may also need to avoid taking fosinopril with aliskiren if you have kidney disease.\nTo make sure fosinopril is safe for you, tell your doctor if you have:\nkidney disease (or if you are on dialysis);\ncirrhosis or other liver disease;\na connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;\nif you are on a low-salt diet; or\nif you have ever had a severe allergic reaction.\nDo not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Fosinopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.\nFosinopril can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.\nDo not give this medication to a child younger than 6 years old.\nHow should I take fosinopril?\nFollow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use fosinopril in larger or smaller amounts or for longer than recommended.\nFosinopril can be taken with or without food.\nCall your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking fosinopril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.\nWhile using fosinopril, you may need frequent blood tests at your doctor's office. Your blood pressure will need to be checked often.\nIf you need surgery or medical tests, tell the doctor ahead of time that you are using fosinopril. You may need to stop using the medicine for a short time.\nIf you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.\nStore at room temperature away from moisture and heat.\nWhat happens if I miss a dose?\nTake the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.\nWhat happens if I overdose?\nSeek emergency medical attention or call the Poison Help line at 1-800-222-1222."}]}, {"title": "dosage_fosinopril", "paragraphs": [{"qas": [{"question": "what is good dose of Fosinopril for childern?", "id": 1513, "answers": [{"text": "6 to 16 years:Greater than 50 kg: 5 to 10 mg orally once a day as monotherapyLess than 50 kg", "answer_start": 1578}], "is_impossible": false}, {"question": "What is usual adult dose of Fosinopril for hypertension?", "id": 1514, "answers": [{"text": "10 mg orally once a day alone or in combination with a diureticMaintenance dose: 20 to 40 mg orally once a day;10 mg orally once a day alone or in combination with a diureticMaintenance dose: 20 to 40 mg orally once a day;10 mg orally once a day alone or in combination with a diureticMaintenance dose: 20 to 40 mg orally once a day;", "answer_start": -1}], "is_impossible": false}, {"question": "What is usual adult dose of Fosinopril for Congestive Heart Failure?", "id": 1515, "answers": [{"text": "10 mg orally once a day Target dose range: 20 to 40 mg orally once a dayMaximum dose: 40 mg orally10 mg orally once a day Target dose range: 20 to 40 mg orally once a dayMaximum dose: 40 mg orally10 mg orally once a day Target dose range: 20 to 40 mg orally once a dayMaximum dose: 40 mg orally", "answer_start": -1}], "is_impossible": false}], "context": "Usual Adult Dose for Hypertension:\nInitial dose: 10 mg orally once a day alone or in combination with a diureticMaintenance dose: 20 to 40 mg orally once a day; some patients may have further response at 80 mg once a dayComments:-Dosages should be adjusted according to blood pressure response at peak (2 to 6 hours post dose) and trough (about 24 hours after dosing) blood levels.-Consider dividing the daily dose in patients where the trough response is inadequate.-Stop the diuretic 2 to 3 days prior to beginning therapy with this drug; it may be resumed at a later time if clinically indicated.-If stopping the diuretic is not possible, careful medical supervision is recommended for several hours until blood pressure has stabilized. Uses: For the treatment of hypertension alone or in combination with other medications\nUsual Adult Dose for Congestive Heart Failure:\nInitial dose: 10 mg orally once a day Target dose range: 20 to 40 mg orally once a dayMaximum dose: 40 mg orally once a dayComments:-Patients should be observed under medical supervision for at least 2 hours following the initial dose until blood pressure stabilizes.-Dosages should be increased over a several week period based on tolerability. -The presence of hypotension, orthostasis, or azotemia early in dose titration should not preclude further careful dose titration; consider dose reducing concomitant diuretic.Use: For the management of heart failure as adjunctive therapy when added to conventional therapy including diuretics with or without digitalis\nUsual Pediatric Dose for Hypertension:\n6 to 16 years:Greater than 50 kg: 5 to 10 mg orally once a day as monotherapyLess than 50 kg: Appropriate dose not available\nDetailed Fosinopril dosage information"}]}]}