Models:
Philip Bordner
philipB/
NER-medical-text
0
Downloads: 1
Diff of /html_files/25572898.html [000000] .. [c0f169]

Switch to unified view

a b/html_files/25572898.html 

  1
  





  
  

  2
  
    <!DOCTYPE html>





  
  

  3
  
    <html>





  
  

  4
  
    <head>





  
  

  5
  
        <meta charset="utf-8">





  
  

  6
  
        <title>25572898 Visualization</title>





  
  

  7
  
    </head>





  
  

  8
  
    <body>





  
  

  9
  
        <h1>25572898 Visualization</h1>





  
  

  10
  
        <p><a href="main.html">Back to Main Page</a></p>





  
  

  11
  
        <div class="entities" style="line-height: 2.5; direction: ltr">A 





  
  

  12
  
<mark class="entity" style="background: #f6c3d0; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  13
  
    42





  
  

  14
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Age</span>





  
  

  15
  
</mark>





  
  

  16
  
 





  
  

  17
  
<mark class="entity" style="background: #f6c3d0; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  18
  
    year





  
  

  19
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Age</span>





  
  

  20
  
</mark>





  
  

  21
  
-





  
  

  22
  
<mark class="entity" style="background: #f6c3d0; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  23
  
    old





  
  

  24
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Age</span>





  
  

  25
  
</mark>





  
  

  26
  
 





  
  

  27
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  28
  
    man





  
  

  29
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sex</span>





  
  

  30
  
</mark>





  
  

  31
  
 with 





  
  

  32
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  33
  
    chronic





  
  

  34
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  35
  
</mark>





  
  

  36
  
 





  
  

  37
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  38
  
    lymphocytic





  
  

  39
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  40
  
</mark>





  
  

  41
  
 





  
  

  42
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  43
  
    leukemia





  
  

  44
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  45
  
</mark>





  
  

  46
  
 underwent 





  
  

  47
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  48
  
    allogeneic





  
  

  49
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  50
  
</mark>





  
  

  51
  
 





  
  

  52
  
<mark class="entity" style="background: #e6ccb2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  53
  
    bone





  
  

  54
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Therapeutic_procedure</span>





  
  

  55
  
</mark>





  
  

  56
  
 





  
  

  57
  
<mark class="entity" style="background: #e6ccb2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  58
  
    marrow





  
  

  59
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Therapeutic_procedure</span>





  
  

  60
  
</mark>





  
  

  61
  
 





  
  

  62
  
<mark class="entity" style="background: #e6ccb2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  63
  
    transplant





  
  

  64
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Therapeutic_procedure</span>





  
  

  65
  
</mark>





  
  

  66
  
 in 





  
  

  67
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  68
  
    September





  
  

  69
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  70
  
</mark>





  
  

  71
  
 





  
  

  72
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  73
  
    2013





  
  

  74
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  75
  
</mark>





  
  

  76
  
.</br>The 





  
  

  77
  
<mark class="entity" style="background: #e3b5a4; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  78
  
    graft





  
  

  79
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Coreference</span>





  
  

  80
  
</mark>





  
  

  81
  
 was 





  
  

  82
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  83
  
    mismatched





  
  

  84
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  85
  
</mark>





  
  

  86
  
 





  
  

  87
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  88
  
    at





  
  

  89
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  90
  
</mark>





  
  

  91
  
 





  
  

  92
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  93
  
    a





  
  

  94
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  95
  
</mark>





  
  

  96
  
 





  
  

  97
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  98
  
    single





  
  

  99
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  100
  
</mark>





  
  

  101
  
 





  
  

  102
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  103
  
    human





  
  

  104
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  105
  
</mark>





  
  

  106
  
 





  
  

  107
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  108
  
    leukocyte





  
  

  109
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  110
  
</mark>





  
  

  111
  
 





  
  

  112
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  113
  
    antigen





  
  

  114
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  115
  
</mark>





  
  

  116
  
 





  
  

  117
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  118
  
    allele





  
  

  119
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  120
  
</mark>





  
  

  121
  
 (





  
  

  122
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  123
  
    DQB1





  
  

  124
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  125
  
</mark>





  
  

  126
  
), and was 





  
  

  127
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  128
  
    T





  
  

  129
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  130
  
</mark>





  
  

  131
  
-





  
  

  132
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  133
  
    cell





  
  

  134
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  135
  
</mark>





  
  

  136
  
 





  
  

  137
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  138
  
    depleted





  
  

  139
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  140
  
</mark>





  
  

  141
  
 using 





  
  

  142
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  143
  
    in





  
  

  144
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  145
  
</mark>





  
  

  146
  
 





  
  

  147
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  148
  
    vivo





  
  

  149
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  150
  
</mark>





  
  

  151
  
 





  
  

  152
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  153
  
    alemtuzumab





  
  

  154
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  155
  
</mark>





  
  

  156
  
.</br>He 





  
  

  157
  
<mark class="entity" style="background: #e6ccb2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  158
  
    engrafted





  
  

  159
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Therapeutic_procedure</span>





  
  

  160
  
</mark>





  
  

  161
  
 on 





  
  

  162
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  163
  
    day





  
  

  164
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  165
  
</mark>





  
  

  166
  
 





  
  

  167
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  168
  
    12





  
  

  169
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  170
  
</mark>





  
  

  171
  
 after 





  
  

  172
  
<mark class="entity" style="background: #e6ccb2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  173
  
    transplant





  
  

  174
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Therapeutic_procedure</span>





  
  

  175
  
</mark>





  
  

  176
  
.</br>Aside from 





  
  

  177
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  178
  
    persistent





  
  

  179
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  180
  
</mark>





  
  

  181
  
 





  
  

  182
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  183
  
    lymphopenia





  
  

  184
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  185
  
</mark>





  
  

  186
  
 and 





  
  

  187
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  188
  
    diarrhea





  
  

  189
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  190
  
</mark>





  
  

  191
  
 from 





  
  

  192
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  193
  
    norovirus





  
  

  194
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  195
  
</mark>





  
  

  196
  
 infection, his 





  
  

  197
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  198
  
    posttransplant





  
  

  199
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  200
  
</mark>





  
  

  201
  
 





  
  

  202
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  203
  
    course





  
  

  204
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  205
  
</mark>





  
  

  206
  
 was 





  
  

  207
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  208
  
    unremarkable





  
  

  209
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  210
  
</mark>





  
  

  211
  
 until 





  
  

  212
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  213
  
    mid





  
  

  214
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  215
  
</mark>





  
  

  216
  
-





  
  

  217
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  218
  
    October





  
  

  219
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  220
  
</mark>





  
  

  221
  
 when he developed 





  
  

  222
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  223
  
    tinnitus





  
  

  224
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  225
  
</mark>





  
  

  226
  
 and 





  
  

  227
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  228
  
    rapidly





  
  

  229
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  230
  
</mark>





  
  

  231
  
 





  
  

  232
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  233
  
    progressive





  
  

  234
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  235
  
</mark>





  
  

  236
  
 





  
  

  237
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  238
  
    sensorineural





  
  

  239
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  240
  
</mark>





  
  

  241
  
 





  
  

  242
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  243
  
    deafness





  
  

  244
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  245
  
</mark>





  
  

  246
  
, resulting in 





  
  

  247
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  248
  
    subtotal





  
  

  249
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  250
  
</mark>





  
  

  251
  
 





  
  

  252
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  253
  
    hearing





  
  

  254
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  255
  
</mark>





  
  

  256
  
 





  
  

  257
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  258
  
    loss





  
  

  259
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  260
  
</mark>





  
  

  261
  
 





  
  

  262
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  263
  
    bilaterally





  
  

  264
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  265
  
</mark>





  
  

  266
  
 (





  
  

  267
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  268
  
    &gt;95





  
  

  269
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  270
  
</mark>





  
  

  271
  
 





  
  

  272
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  273
  
    dB





  
  

  274
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  275
  
</mark>





  
  

  276
  
) 





  
  

  277
  
<mark class="entity" style="background: #ffdfba; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  278
  
    over





  
  

  279
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Duration</span>





  
  

  280
  
</mark>





  
  

  281
  
 2–3 





  
  

  282
  
<mark class="entity" style="background: #ffdfba; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  283
  
    weeks





  
  

  284
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Duration</span>





  
  

  285
  
</mark>





  
  

  286
  
.</br>





  
  

  287
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  288
  
    Brain





  
  

  289
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  290
  
</mark>





  
  

  291
  
 





  
  

  292
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  293
  
    magnetic





  
  

  294
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  295
  
</mark>





  
  

  296
  
 





  
  

  297
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  298
  
    resonance





  
  

  299
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  300
  
</mark>





  
  

  301
  
 





  
  

  302
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  303
  
    imaging





  
  

  304
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  305
  
</mark>





  
  

  306
  
 (





  
  

  307
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  308
  
    MRI





  
  

  309
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  310
  
</mark>





  
  

  311
  
) was unremarkable, as was 





  
  

  312
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  313
  
    cerebrospinal





  
  

  314
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  315
  
</mark>





  
  

  316
  
 





  
  

  317
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  318
  
    fluid





  
  

  319
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  320
  
</mark>





  
  

  321
  
 (





  
  

  322
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  323
  
    CSF





  
  

  324
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  325
  
</mark>





  
  

  326
  
) analysis (





  
  

  327
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  328
  
    4





  
  

  329
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  330
  
</mark>





  
  

  331
  
 





  
  

  332
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  333
  
    leukocytes/µL





  
  

  334
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  335
  
</mark>





  
  

  336
  
 with 





  
  

  337
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  338
  
    50%





  
  

  339
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  340
  
</mark>





  
  

  341
  
 





  
  

  342
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  343
  
    neutrophils





  
  

  344
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  345
  
</mark>





  
  

  346
  
 and 





  
  

  347
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  348
  
    50%





  
  

  349
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  350
  
</mark>





  
  

  351
  
 





  
  

  352
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  353
  
    lymphocytes





  
  

  354
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  355
  
</mark>





  
  

  356
  
, 





  
  

  357
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  358
  
    6





  
  

  359
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  360
  
</mark>





  
  

  361
  
 





  
  

  362
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  363
  
    red





  
  

  364
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  365
  
</mark>





  
  

  366
  
 





  
  

  367
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  368
  
    blood





  
  

  369
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  370
  
</mark>





  
  

  371
  
 





  
  

  372
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  373
  
    cells/µL





  
  

  374
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  375
  
</mark>





  
  

  376
  
, 





  
  

  377
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  378
  
    glucose





  
  

  379
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  380
  
</mark>





  
  

  381
  
 





  
  

  382
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  383
  
    2.4





  
  

  384
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  385
  
</mark>





  
  

  386
  
 





  
  

  387
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  388
  
    mmol/L





  
  

  389
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  390
  
</mark>





  
  

  391
  
 [normal range, 2.2–4.7 mmol/L], 





  
  

  392
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  393
  
    protein





  
  

  394
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  395
  
</mark>





  
  

  396
  
 





  
  

  397
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  398
  
    61





  
  

  399
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  400
  
</mark>





  
  

  401
  
 





  
  

  402
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  403
  
    mg/dL





  
  

  404
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  405
  
</mark>





  
  

  406
  
 [normal range, 15–45 mg/L], 





  
  

  407
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  408
  
    absence





  
  

  409
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  410
  
</mark>





  
  

  411
  
 of 





  
  

  412
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  413
  
    oligoclonal





  
  

  414
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  415
  
</mark>





  
  

  416
  
 





  
  

  417
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  418
  
    bands





  
  

  419
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  420
  
</mark>





  
  

  421
  
).</br>





  
  

  422
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  423
  
    Viral





  
  

  424
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  425
  
</mark>





  
  

  426
  
 





  
  

  427
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  428
  
    polymerase





  
  

  429
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  430
  
</mark>





  
  

  431
  
 





  
  

  432
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  433
  
    chain





  
  

  434
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  435
  
</mark>





  
  

  436
  
 





  
  

  437
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  438
  
    reaction





  
  

  439
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  440
  
</mark>





  
  

  441
  
 (PCR) testing of 





  
  

  442
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  443
  
    CSF





  
  

  444
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  445
  
</mark>





  
  

  446
  
 was negative for 





  
  

  447
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  448
  
    enterovirus





  
  

  449
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  450
  
</mark>





  
  

  451
  
 and 





  
  

  452
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  453
  
    herpesvirus





  
  

  454
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  455
  
</mark>





  
  

  456
  
 infection.</br>The patient was treated empirically with high-dose 





  
  

  457
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  458
  
    valacyclovir





  
  

  459
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  460
  
</mark>





  
  

  461
  
, broad-spectrum 





  
  

  462
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  463
  
    antibiotics





  
  

  464
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  465
  
</mark>





  
  

  466
  
, and 





  
  

  467
  
<mark class="entity" style="background: #b9e8d8; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  468
  
    2





  
  

  469
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Dosage</span>





  
  

  470
  
</mark>





  
  

  471
  
 





  
  

  472
  
<mark class="entity" style="background: #b9e8d8; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  473
  
    g/kg





  
  

  474
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Dosage</span>





  
  

  475
  
</mark>





  
  

  476
  
 





  
  

  477
  
<mark class="entity" style="background: #f7a399; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  478
  
    intravenous





  
  

  479
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Administration</span>





  
  

  480
  
</mark>





  
  

  481
  
 





  
  

  482
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  483
  
    immunoglobulin





  
  

  484
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  485
  
</mark>





  
  

  486
  
 (





  
  

  487
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  488
  
    IVIG





  
  

  489
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  490
  
</mark>





  
  

  491
  
).</br>Despite these interventions, he developed new symptoms of central 





  
  

  492
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  493
  
    dyspnea





  
  

  494
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  495
  
</mark>





  
  

  496
  
, 





  
  

  497
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  498
  
    postural





  
  

  499
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  500
  
</mark>





  
  

  501
  
 





  
  

  502
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  503
  
    hypotension





  
  

  504
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  505
  
</mark>





  
  

  506
  
, 





  
  

  507
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  508
  
    nausea





  
  

  509
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  510
  
</mark>





  
  

  511
  
, and 





  
  

  512
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  513
  
    gradually





  
  

  514
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  515
  
</mark>





  
  

  516
  
 





  
  

  517
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  518
  
    worsening





  
  

  519
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  520
  
</mark>





  
  

  521
  
 





  
  

  522
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  523
  
    balance





  
  

  524
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  525
  
</mark>





  
  

  526
  
.</br>Repeat 





  
  

  527
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  528
  
    neurological





  
  

  529
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  530
  
</mark>





  
  

  531
  
 





  
  

  532
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  533
  
    assessment





  
  

  534
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  535
  
</mark>





  
  

  536
  
 confirmed 





  
  

  537
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  538
  
    persistent





  
  

  539
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  540
  
</mark>





  
  

  541
  
 





  
  

  542
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  543
  
    vestibulocochlear





  
  

  544
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  545
  
</mark>





  
  

  546
  
 





  
  

  547
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  548
  
    dysfunction





  
  

  549
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  550
  
</mark>





  
  

  551
  
 





  
  

  552
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  553
  
    6





  
  

  554
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  555
  
</mark>





  
  

  556
  
 





  
  

  557
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  558
  
    weeks





  
  

  559
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  560
  
</mark>





  
  

  561
  
 





  
  

  562
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  563
  
    after





  
  

  564
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  565
  
</mark>





  
  

  566
  
 





  
  

  567
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  568
  
    symptom





  
  

  569
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  570
  
</mark>





  
  

  571
  
 onset.</br>By 





  
  

  572
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  573
  
    mid





  
  

  574
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  575
  
</mark>





  
  

  576
  
-





  
  

  577
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  578
  
    December





  
  

  579
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  580
  
</mark>





  
  

  581
  
, the patient had become increasingly 





  
  

  582
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  583
  
    withdrawn





  
  

  584
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  585
  
</mark>





  
  

  586
  
, 





  
  

  587
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  588
  
    irritable





  
  

  589
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  590
  
</mark>





  
  

  591
  
, and 





  
  

  592
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  593
  
    intermittently





  
  

  594
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  595
  
</mark>





  
  

  596
  
 





  
  

  597
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  598
  
    agitated





  
  

  599
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  600
  
</mark>





  
  

  601
  
.</br>He remained 





  
  

  602
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  603
  
    lymphopenic





  
  

  604
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  605
  
</mark>





  
  

  606
  
 (





  
  

  607
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  608
  
    lymphocytes





  
  

  609
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  610
  
</mark>





  
  

  611
  
 





  
  

  612
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  613
  
    0.54





  
  

  614
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  615
  
</mark>





  
  

  616
  
 





  
  

  617
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  618
  
    ×





  
  

  619
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  620
  
</mark>





  
  

  621
  
 





  
  

  622
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  623
  
    106/μL





  
  

  624
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  625
  
</mark>





  
  

  626
  
 [normal range, 1.2–3.6 × 106/μL]).</br>





  
  

  627
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  628
  
    MRI





  
  

  629
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  630
  
</mark>





  
  

  631
  
 scans of the 





  
  

  632
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  633
  
    brain





  
  

  634
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  635
  
</mark>





  
  

  636
  
 were 





  
  

  637
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  638
  
    unremarkable





  
  

  639
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  640
  
</mark>





  
  

  641
  
, as was 





  
  

  642
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  643
  
    serum





  
  

  644
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  645
  
</mark>





  
  

  646
  
 





  
  

  647
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  648
  
    testing





  
  

  649
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  650
  
</mark>





  
  

  651
  
 for 





  
  

  652
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  653
  
    antineuronal





  
  

  654
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  655
  
</mark>





  
  

  656
  
 





  
  

  657
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  658
  
    antibodies





  
  

  659
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  660
  
</mark>





  
  

  661
  
; an 





  
  

  662
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  663
  
    electroencephalogram





  
  

  664
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  665
  
</mark>





  
  

  666
  
 revealed only diffuse 





  
  

  667
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  668
  
    encephalopathy





  
  

  669
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  670
  
</mark>





  
  

  671
  
.</br>Given continued suspicion for a 





  
  

  672
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  673
  
    viral





  
  

  674
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  675
  
</mark>





  
  

  676
  
 etiology, the patient was treated with 





  
  

  677
  
<mark class="entity" style="background: #b9e8d8; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  678
  
    high





  
  

  679
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Dosage</span>





  
  

  680
  
</mark>





  
  

  681
  
-





  
  

  682
  
<mark class="entity" style="background: #b9e8d8; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  683
  
    dose





  
  

  684
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Dosage</span>





  
  

  685
  
</mark>





  
  

  686
  
 





  
  

  687
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  688
  
    glucocorticoids





  
  

  689
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  690
  
</mark>





  
  

  691
  
 and again with 





  
  

  692
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  693
  
    IVIG





  
  

  694
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  695
  
</mark>





  
  

  696
  
.</br>He began refusing 





  
  

  697
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  698
  
    fluids





  
  

  699
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Activity</span>





  
  

  700
  
</mark>





  
  

  701
  
, 





  
  

  702
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  703
  
    food





  
  

  704
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Activity</span>





  
  

  705
  
</mark>





  
  

  706
  
, and 





  
  

  707
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  708
  
    medication





  
  

  709
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  710
  
</mark>





  
  

  711
  
, and was 





  
  

  712
  
<mark class="entity" style="background: #77c5d5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  713
  
    detained





  
  

  714
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Clinical_event</span>





  
  

  715
  
</mark>





  
  

  716
  
 under the 





  
  

  717
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  718
  
    UK





  
  

  719
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  720
  
</mark>





  
  

  721
  
 





  
  

  722
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  723
  
    Mental





  
  

  724
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  725
  
</mark>





  
  

  726
  
 





  
  

  727
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  728
  
    Health





  
  

  729
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  730
  
</mark>





  
  

  731
  
 





  
  

  732
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  733
  
    Act





  
  

  734
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  735
  
</mark>





  
  

  736
  
.</br>Repeat 





  
  

  737
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  738
  
    MRI





  
  

  739
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  740
  
</mark>





  
  

  741
  
 scanning showed interval development of 





  
  

  742
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  743
  
    new





  
  

  744
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  745
  
</mark>





  
  

  746
  
, 





  
  

  747
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  748
  
    nonenhancing





  
  

  749
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  750
  
</mark>





  
  

  751
  
 





  
  

  752
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  753
  
    signal





  
  

  754
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  755
  
</mark>





  
  

  756
  
 





  
  

  757
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  758
  
    abnormalities





  
  

  759
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  760
  
</mark>





  
  

  761
  
 in 





  
  

  762
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  763
  
    both





  
  

  764
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  765
  
</mark>





  
  

  766
  
 





  
  

  767
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  768
  
    thalami





  
  

  769
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  770
  
</mark>





  
  

  771
  
 and 





  
  

  772
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  773
  
    midbrain





  
  

  774
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  775
  
</mark>





  
  

  776
  
 with 





  
  

  777
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  778
  
    cranial





  
  

  779
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  780
  
</mark>





  
  

  781
  
 





  
  

  782
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  783
  
    nerve





  
  

  784
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  785
  
</mark>





  
  

  786
  
 involvement but no 





  
  

  787
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  788
  
    meningeal





  
  

  789
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  790
  
</mark>





  
  

  791
  
 





  
  

  792
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  793
  
    enhancement





  
  

  794
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  795
  
</mark>





  
  

  796
  
 (Figure ​1A).</br>





  
  

  797
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  798
  
    Near





  
  

  799
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  800
  
</mark>





  
  

  801
  
 





  
  

  802
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  803
  
    the





  
  

  804
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  805
  
</mark>





  
  

  806
  
 





  
  

  807
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  808
  
    end





  
  

  809
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  810
  
</mark>





  
  

  811
  
 





  
  

  812
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  813
  
    of





  
  

  814
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  815
  
</mark>





  
  

  816
  
 





  
  

  817
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  818
  
    December





  
  

  819
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  820
  
</mark>





  
  

  821
  
, a 





  
  

  822
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  823
  
    frontal





  
  

  824
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  825
  
</mark>





  
  

  826
  
 





  
  

  827
  
<mark class="entity" style="background: #9ddfd3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  828
  
    lobe





  
  

  829
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Biological_structure</span>





  
  

  830
  
</mark>





  
  

  831
  
 





  
  

  832
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  833
  
    biopsy





  
  

  834
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  835
  
</mark>





  
  

  836
  
 was performed.</br>





  
  

  837
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  838
  
    Histology





  
  

  839
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  840
  
</mark>





  
  

  841
  
 revealed 





  
  

  842
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  843
  
    reactive





  
  

  844
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  845
  
</mark>





  
  

  846
  
 





  
  

  847
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  848
  
    gliosis





  
  

  849
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  850
  
</mark>





  
  

  851
  
 and 





  
  

  852
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  853
  
    diffuse





  
  

  854
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  855
  
</mark>





  
  

  856
  
 





  
  

  857
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  858
  
    infiltration





  
  

  859
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  860
  
</mark>





  
  

  861
  
 with 





  
  

  862
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  863
  
    CD3+/8+





  
  

  864
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  865
  
</mark>





  
  

  866
  
 





  
  

  867
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  868
  
    lymphocytes





  
  

  869
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  870
  
</mark>





  
  

  871
  
 (Figure 1B).</br>Extensive 





  
  

  872
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  873
  
    microbiological





  
  

  874
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  875
  
</mark>





  
  

  876
  
 





  
  

  877
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  878
  
    testing





  
  

  879
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  880
  
</mark>





  
  

  881
  
 of the 





  
  

  882
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  883
  
    biopsy





  
  

  884
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  885
  
</mark>





  
  

  886
  
 





  
  

  887
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  888
  
    tissue





  
  

  889
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  890
  
</mark>





  
  

  891
  
 for an 





  
  

  892
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  893
  
    infectious





  
  

  894
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  895
  
</mark>





  
  

  896
  
 





  
  

  897
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  898
  
    etiology





  
  

  899
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  900
  
</mark>





  
  

  901
  
 was 





  
  

  902
  
<mark class="entity" style="background: #f4b3c2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  903
  
    negative





  
  

  904
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Lab_value</span>





  
  

  905
  
</mark>





  
  

  906
  
 (Supplementary Table 1).</br>Given the absence of a diagnosis and the patient's progressive 





  
  

  907
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  908
  
    neurological





  
  

  909
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  910
  
</mark>





  
  

  911
  
 





  
  

  912
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  913
  
    deterioration





  
  

  914
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  915
  
</mark>





  
  

  916
  
, 





  
  

  917
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  918
  
    CSF





  
  

  919
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  920
  
</mark>





  
  

  921
  
 





  
  

  922
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  923
  
    and





  
  

  924
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  925
  
</mark>





  
  

  926
  
 





  
  

  927
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  928
  
    brain





  
  

  929
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  930
  
</mark>





  
  

  931
  
 





  
  

  932
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  933
  
    biopsy





  
  

  934
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  935
  
</mark>





  
  

  936
  
 





  
  

  937
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  938
  
    tissue





  
  

  939
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  940
  
</mark>





  
  

  941
  
 were analyzed in 





  
  

  942
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  943
  
    January





  
  

  944
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  945
  
</mark>





  
  

  946
  
 





  
  

  947
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  948
  
    2014





  
  

  949
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  950
  
</mark>





  
  

  951
  
 by 





  
  

  952
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  953
  
    metagenomic





  
  

  954
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  955
  
</mark>





  
  

  956
  
 





  
  

  957
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  958
  
    next





  
  

  959
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  960
  
</mark>





  
  

  961
  
-





  
  

  962
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  963
  
    generation





  
  

  964
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  965
  
</mark>





  
  

  966
  
 





  
  

  967
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  968
  
    sequencing





  
  

  969
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  970
  
</mark>





  
  

  971
  
 (





  
  

  972
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  973
  
    NGS





  
  

  974
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  975
  
</mark>





  
  

  976
  
) [2].</br>





  
  

  977
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  978
  
    NGS





  
  

  979
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  980
  
</mark>





  
  

  981
  
 analysis of the 





  
  

  982
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  983
  
    brain





  
  

  984
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  985
  
</mark>





  
  

  986
  
 





  
  

  987
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  988
  
    biopsy





  
  

  989
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  990
  
</mark>





  
  

  991
  
, 





  
  

  992
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  993
  
    genome





  
  

  994
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  995
  
</mark>





  
  

  996
  
 





  
  

  997
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  998
  
    assembly





  
  

  999
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  1000
  
</mark>





  
  

  1001
  
, and 





  
  

  1002
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1003
  
    in





  
  

  1004
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  1005
  
</mark>





  
  

  1006
  
 





  
  

  1007
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1008
  
    situ





  
  

  1009
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  1010
  
</mark>





  
  

  1011
  
 





  
  

  1012
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1013
  
    hybridization





  
  

  1014
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  1015
  
</mark>





  
  

  1016
  
 revealed findings of 





  
  

  1017
  
<mark class="entity" style="background: #ffb347; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1018
  
    neuroinvasive





  
  

  1019
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Detailed_description</span>





  
  

  1020
  
</mark>





  
  

  1021
  
 





  
  

  1022
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1023
  
    astrovirus





  
  

  1024
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  1025
  
</mark>





  
  

  1026
  
 (





  
  

  1027
  
<mark class="entity" style="background: #c4b7ea; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1028
  
    AstV





  
  

  1029
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Disease_disorder</span>





  
  

  1030
  
</mark>





  
  

  1031
  
) infection.</br>Despite lack of approved therapies, the patient was treated with 





  
  

  1032
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1033
  
    ribavirin





  
  

  1034
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  1035
  
</mark>





  
  

  1036
  
 and 





  
  

  1037
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1038
  
    IVIG





  
  

  1039
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  1040
  
</mark>





  
  

  1041
  
.</br>However, he did not respond to these interventions, and remained in a 





  
  

  1042
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1043
  
    minimally





  
  

  1044
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  1045
  
</mark>





  
  

  1046
  
 





  
  

  1047
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1048
  
    conscious





  
  

  1049
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  1050
  
</mark>





  
  

  1051
  
 





  
  

  1052
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1053
  
    state





  
  

  1054
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  1055
  
</mark>





  
  

  1056
  
 following withdrawal of 





  
  

  1057
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1058
  
    sedation





  
  

  1059
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Medication</span>





  
  

  1060
  
</mark>





  
  

  1061
  
 in 





  
  

  1062
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1063
  
    March





  
  

  1064
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1065
  
</mark>





  
  

  1066
  
 





  
  

  1067
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1068
  
    2014





  
  

  1069
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1070
  
</mark>





  
  

  1071
  
.</br>He eventually 





  
  

  1072
  
<mark class="entity" style="background: #f9d5e5; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1073
  
    died





  
  

  1074
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Activity</span>





  
  

  1075
  
</mark>





  
  

  1076
  
 at the 





  
  

  1077
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1078
  
    end





  
  

  1079
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1080
  
</mark>





  
  

  1081
  
 





  
  

  1082
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1083
  
    of





  
  

  1084
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1085
  
</mark>





  
  

  1086
  
 





  
  

  1087
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1088
  
    May





  
  

  1089
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1090
  
</mark>





  
  

  1091
  
, 





  
  

  1092
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1093
  
    4





  
  

  1094
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1095
  
</mark>





  
  

  1096
  
 





  
  

  1097
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1098
  
    months





  
  

  1099
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1100
  
</mark>





  
  

  1101
  
 





  
  

  1102
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1103
  
    after





  
  

  1104
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1105
  
</mark>





  
  

  1106
  
 the 





  
  

  1107
  
<mark class="entity" style="background: #c5b4e3; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1108
  
    NGS





  
  

  1109
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Diagnostic_procedure</span>





  
  

  1110
  
</mark>





  
  

  1111
  
 diagnosis and approximately 





  
  

  1112
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1113
  
    7.5





  
  

  1114
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1115
  
</mark>





  
  

  1116
  
 





  
  

  1117
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1118
  
    months





  
  

  1119
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1120
  
</mark>





  
  

  1121
  
 





  
  

  1122
  
<mark class="entity" style="background: #f1f0d2; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1123
  
    after





  
  

  1124
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Date</span>





  
  

  1125
  
</mark>





  
  

  1126
  
 onset of 





  
  

  1127
  
<mark class="entity" style="background: #bde0fe; padding: 0.45em 0.6em; margin: 0 0.25em; line-height: 1; border-radius: 0.35em;">





  
  

  1128
  
    symptoms





  
  

  1129
  
    <span style="font-size: 0.8em; font-weight: bold; line-height: 1; border-radius: 0.35em; vertical-align: middle; margin-left: 0.5rem">Sign_symptom</span>





  
  

  1130
  
</mark>





  
  

  1131
  
.</br></div>





  
  

  1132
  
    </body>





  
  

  1133
  
    </html>





  
  

  1134