Remicade reduces the effects of a substance in the body that can cause
inflammation.

Remicade is used to treat rheumatoid arthritis, psoriatic arthritis,
ankylosing spondylitis and severe or disabling plaque psoriasis in adults.

Remicade is also used to treat ulcerative colitis and Crohn's disease in
adults and children at least 6 years old.

Infliximab is often used when other medicines have not been effective.





Some side effects may occur during the injection. Tell your caregiver if you
feel dizzy, nauseated, light-headed, itchy or tingly, short of breath, or have
a headache, fever, chills, muscle or joint pain, pain or tightness in your
throat, chest pain, or trouble swallowing during the injection. Infusion
reactions may also occur within 1 or 2 hours after injection.

Get emergency medical help if you have **signs of an allergic reaction to
Remicade** : hives; chest pain, difficult breathing; fever, chills, severe
dizziness; swelling of your face, lips, tongue, or throat.

**Serious and sometimes fatal infections may occur during treatment with
Remicade.** Call your doctor right away if you have signs of infection such
as: fever, extreme tiredness, flu symptoms, cough, or skin symptoms (pain,
warmth, or redness).

Also call your doctor if you have:

  * skin changes, new growths on the skin;

  * pale skin, easy bruising or bleeding;

  * **delayed allergic reaction (up to 12 days after receiving Remicade)** \- fever, sore throat, trouble swallowing, headache, joint or muscle pain, skin rash, or swelling in your face or hands;

  * **liver problems** \- right-sided upper stomach pain, loss of appetite, yellowing of your skin or eyes (jaundice), and not feeling well;

  * **lupus-like syndrome** \- joint pain or swelling, chest discomfort, feeling short of breath, skin rash on your cheeks or arms (worsens in sunlight);

  * **nerve problems** \- numbness or tingling, problems with vision, weakness in your arms or legs, seizure;

  * **new or worseningpsoriasis** \- skin redness or scaly patches, raised bumps filled with pus;

  * **signs of heart failure** \- shortness of breath with swelling of your ankles or feet, rapid weight gain;

  * **signs of a stroke** \- sudden numbness or weakness, trouble speaking or understanding what is said to you, problems with vision or balance, severe headache;

  * **signs of lymphoma** \- fever, night sweats, weight loss, stomach pain or swelling, chest pain, cough, trouble breathing, swollen glands (in your neck, armpits, or groin); or

  * **signs of tuberculosis** \- fever, cough, night sweats, loss of appetite, weight loss, feeling constantly tired.

Serious infections may be more likely in adults who are 65 years or older.

Common Remicade side effects may include:

  * stuffy nose, sinus pain;

  * fever, chills, sore throat;

  * cough, chest pain, shortness of breath;

  * high or low blood pressure;

  * headache, feeling light-headed;

  * rash, itching; or

  * stomach pain.

This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to
FDA at 1-800-FDA-1088.

Remicade side effects (more detail)