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+A 62-year-old man with long-standing type 2 diabetes mellitus secondary to chronic calcific pancreatitis with a tendency to hypoglycaemia due to the administration of rapid insulin, multiple admissions for urinary infectious conditions and functional deterioration.
+On admission, he suffered from neglect of personal hygiene with uncontrolled elimination habits, malnutrition, chronic renal failure, diabetic ketoacidosis and a grade III sacral ulcer.
+Culture of the ulcer exudate showed that it was positive for MRSA and methicillin-resistant Staphylococcus aureus (MRSA) and the antibiogram showed that MRSA was sensitive only to colistin (MIC < 2) and intermediate to amikacin (MIC = 16). MRSA was sensitive to co-trimoxazole (MIC < 1/19) and intermediate to clindamycin (MIC = 1.9).
+Treatment was initiated with colistin cream 0.1% with daily application to the dressing and oral cotrimoxazole 800/160 mg every 12 hours for MRSA treatment. After one month of treatment, a favourable clinical evolution of the ulcer was observed, with growth of edges and granulation tissue, which had not been observed prior to topical treatment.
+The patient died due to chronic renal failure exacerbated by urinary sepsis, for which reason a post-treatment culture was not available.
+