A 56-year-old woman with a history of residual pulmonary tuberculosis, bladder carcinoma operated on twice and currently treated with local instillation of mitomycin, diabetes mellitus, arterial hypertension and hyperuricaemia, for the last month on treatment with allopurinol, has attended the emergency department on several occasions over the last 10 days, for attacks of dyspnoea together with skin rash and has been treated from the beginning with high-dose corticosteroids, antihistamines and aerosol therapy.
She was admitted to the ICU with suspected NET, presenting an erythematous maculopapular and blistering rash over 70% of the body surface, positive Nikolsky's sign, type I respiratory failure, mild renal failure and a tendency to hypotension. Supportive treatment and ciclosporin A were started. The patient has evolved favourably, the skin lesions have completely re-epithelialised 21 days after admission to the ICU, and she has been discharged to the ward.