{"protocolSection":{"identificationModule":{"nctId":"NCT03192644","orgStudyIdInfo":{"id":"B2017-004-01"},"briefTitle":"The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) Versus Adjuvant Transarterial Chemoembolization (TACE) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.","officialTitle":"The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) Versus Adjuvant Transarterial Chemoembolization (TACE) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial."},"descriptionModule":{"briefSummary":"To compare the impact on recurrence risk of adjuvant TAI and adjuvant TACE for patients with HCC and PVTT after hepatectomy."},"conditionsModule":{"conditions":["Hepatocellular Carcinoma"]},"eligibilityModule":{"eligibilityCriteria":"Inclusion Criteria:\n\n* older than 18 years old and younger than 75 years;\n* ECOG PS\\<3;\n* proven hepatocellular carcinoma with PVTT according pathological examination;\n* not previous treated for tumor;\n* tumor and tumor thrombosis were removed in operation;\n* no recurrence occurence at 4 to 7 weeks after surgery;\n* the lab test could meet: neutrophil count≥1.5×109/L; hemoglobin≥80g/L; platelet count≥60×109/L; serum albumin≥28g/L; total bilirubin\\<3-times upper limit of normal; ALT\\<5-times upper limit of normal; AST\\<5-times upper limit of normal; serum creatine\\<1.5-times upper limit of normal; PT≤upper limit of normal plus 6 seconds; INR≤2.3;\n* sign up consent;\n* unrolled by other clinical trials about hepatocellular carcinoma.\n\nExclusion Criteria:\n\n* cannot tolerate TACE or TAI;\n* CNS or bone metastasis exits;\n* known history of other malignancy;\n* be allergic to related drugs;\n* underwent organ transplantation before;\n* be treated before (interferon included);\n* known history of HIV infection;\n* known history of drug or alcohol abuse;\n* have GI hemorrhage or cardiac/brain vascular events within 30 days;\n* pregnancy;","healthyVolunteers":false,"sex":"ALL","minimumAge":"18 Years","maximumAge":"75 Years","stdAges":["ADULT","OLDER_ADULT"]}}}