T1  Date 3 20   December 28, 2014

E1  Date:T1 

T2  Age 24 35   70-year-old

T3  Sex 36 39   man

T4  Sign_symptom 65 69  pain

E2  Sign_symptom:T4 

T5  Biological_structure 55 64  abdominal

R1  MODIFY Arg1:T5 Arg2:E2  

T6  Sign_symptom 71 80  dizziness

E3  Sign_symptom:T6 

T7  Sign_symptom 86 92  nausea

E4  Sign_symptom:T7 

T8  Nonbiological_location 113 149  Hebei General Hospital, Hebei, China

T9  Diagnostic_procedure 151 162    Gastroscopy

E5  Diagnostic_procedure:T9 

T10 Disease_disorder 192 210    ulcerative lesions

E6  Disease_disorder:T10 

T11 Shape 170 179   irregular

T12 Detailed_description 180 191    hemorrhagic

R2  MODIFY Arg1:T12 Arg2:E6 

R3  MODIFY Arg1:T11 Arg2:E6 

T13 Biological_structure 230 242    gastric body

T14 Biological_structure 250 266    lesser curvature

R4  MODIFY Arg1:T13 Arg2:E6 

R5  MODIFY Arg1:T14 Arg2:E6 

T15 Disease_disorder 271 287    pyloric stenosis

E7  Disease_disorder:T15 

T16 Biological_structure 295 302    stomach

R6  MODIFY Arg1:T16 Arg2:E7 

T17 Diagnostic_procedure 312 318    biopsy

E8  Diagnostic_procedure:T17 

T18 Biological_structure 304 311    Gastric

R7  MODIFY Arg1:T18 Arg2:E8 

T19 Disease_disorder 328 342    adenocarcinoma

E9  Disease_disorder:T19 

T20 Date 347 362    January 7, 2015

E10 Date:T20 

T21 Therapeutic_procedure 375 386   gastrectomy

E11 Therapeutic_procedure:T21 

T22 Detailed_description 364 374    palliative

R8  MODIFY Arg1:T22 Arg2:E11    

T23 Therapeutic_procedure 392 401   Roux-en-Y

E12 Therapeutic_procedure:T23 

T24 Therapeutic_procedure 407 426   esophagojejunostomy

E13 Therapeutic_procedure:T24 

R9  MODIFY Arg1:E12 Arg2:E13    

T25 Biological_structure 494 516    pancreatic lymph nodes

T26 Biological_structure 476 484    anterior

T27 Biological_structure 485 493    superior

T28 Biological_structure 460 471    para-aortic

R10 MODIFY Arg1:T27 Arg2:T25    

R11 MODIFY Arg1:T26 Arg2:T25    

R12 MODIFY Arg1:T28 Arg2:T25    

T29 Therapeutic_procedure 588 596   resected

E14 Therapeutic_procedure:T29 

A1  POLARITY E14 NEG

R13 MODIFY Arg1:T25 Arg2:E14    

T30 Biological_structure 529 540    lymph nodes

T31 Qualitative_concept 443 450 Diffuse

T32 Qualitative_concept 451 459 enlarged

R14 MODIFY Arg1:T32 Arg2:T25    

R15 MODIFY Arg1:T31 Arg2:T25    

T33 Biological_structure 552 573    common hepatic artery

R16 MODIFY Arg1:T33 Arg2:T30    

R17 MODIFY Arg1:T30 Arg2:E14    

T34 Diagnostic_procedure 612 621    pathology

E15 Diagnostic_procedure:T34 

T35 Disease_disorder 661 683    gastric adenocarcinoma

E16 Disease_disorder:T35 

T36 Severity 635 660    moderately differentiated

R18 MODIFY Arg1:T36 Arg2:E16    

T37 Diagnostic_procedure 694 714    Immunohistochemistry

E17 Diagnostic_procedure:T37 

T38 Diagnostic_procedure 737 777    human epidermal growth factor receptor 2

E18 Diagnostic_procedure:T38 

T39 Diagnostic_procedure 779 784    HER-2

E19 Diagnostic_procedure:T39 

R19 IDENTICAL Arg1:E19 Arg2:E18 

R20 SUB_PROCEDURE Arg1:E18 Arg2:E17 

T40 Lab_value 787 788   +

E20 Lab_value:T40 

R21 MODIFY Arg1:E20 Arg2:E18    

T41 Diagnostic_procedure 791 825    vascular endothelial growth factor

E21 Diagnostic_procedure:T41 

T42 Diagnostic_procedure 827 831    VEGF

E22 Diagnostic_procedure:T42 

T43 Lab_value 834 835   +

E23 Lab_value:T43 

R22 BEFORE Arg1:E23 Arg2:E21    

R23 IDENTICAL Arg1:E22 Arg2:E21 

R24 SUB_PROCEDURE Arg1:E21 Arg2:E17 

T44 Diagnostic_procedure 838 842    CD31

E24 Diagnostic_procedure:T44 

T45 Lab_value 844 845   +

E25 Lab_value:T45 

T46 Diagnostic_procedure 848 853    CD105

E26 Diagnostic_procedure:T46 

T47 Lab_value 855 856   +

E27 Lab_value:T47 

R25 MODIFY Arg1:E27 Arg2:E26    

R26 SUB_PROCEDURE Arg1:E26 Arg2:E17 

R27 MODIFY Arg1:E25 Arg2:E24    

R28 SUB_PROCEDURE Arg1:E24 Arg2:E17 

T48 Diagnostic_procedure 870 885    triple positive

E28 Diagnostic_procedure:T48 

T49 Diagnostic_procedure 887 889    TP

E29 Diagnostic_procedure:T49 

T50 Lab_value 892 893   +

E30 Lab_value:T50 

R29 IDENTICAL Arg1:E29 Arg2:E28 

R30 MODIFY Arg1:E30 Arg2:E28    

R31 SUB_PROCEDURE Arg1:E28 Arg2:E17 

T51 Diagnostic_procedure 896 923    glutathione S-transferase π

E31 Diagnostic_procedure:T51 

T52 Diagnostic_procedure 925 930    GST-π

E32 Diagnostic_procedure:T52 

T53 Lab_value 933 936   +++

E33 Lab_value:T53 

R32 MODIFY Arg1:E33 Arg2:E31    

R33 IDENTICAL Arg1:E32 Arg2:E31 

R34 SUB_PROCEDURE Arg1:E31 Arg2:E17 

T54 Diagnostic_procedure 939 964    topoisomerase enzyme II α

E34 Diagnostic_procedure:T54 

T55 Diagnostic_procedure 966 974    TOPOII α

E35 Diagnostic_procedure:T55 

R35 IDENTICAL Arg1:E35 Arg2:E34 

T56 Diagnostic_procedure 977 980    P53

E36 Diagnostic_procedure:T56 

T57 Lab_value 982 983   –

E37 Lab_value:T57 

T58 Diagnostic_procedure 990 995    Ki-67

E38 Diagnostic_procedure:T58 

T59 Lab_value 997 1000  70%

E39 Lab_value:T59 

R36 MODIFY Arg1:E37 Arg2:E36    

R37 MODIFY Arg1:E39 Arg2:E38    

R38 SUB_PROCEDURE Arg1:E34 Arg2:E17 

R39 SUB_PROCEDURE Arg1:E36 Arg2:E17 

R40 SUB_PROCEDURE Arg1:E38 Arg2:E17 

T60 Disease_disorder 1030 1052  gastric adenocarcinoma

E40 Disease_disorder:T60 

T61 Severity 1021 1029  stage IV

R41 MODIFY Arg1:T61 Arg2:E40    

T62 Qualitative_concept 1058 1066   multiple

T63 Biological_structure 1067 1077  lymphnodes

T64 Disease_disorder 1078 1088  metastases

E41 Disease_disorder:T64 

T65 Severity 1090 1096  T4N2M1

R42 MODIFY Arg1:T65 Arg2:E40    

R43 MODIFY Arg1:T63 Arg2:E41    

R44 MODIFY Arg1:T62 Arg2:E41    

T66 Therapeutic_procedure 1130 1151 cycle of chemotherapy

E42 Therapeutic_procedure:T66 

T67 Dosage 1128 1129    1

R45 MODIFY Arg1:T67 Arg2:E42    

T68 Medication 1157 1168    oxaliplatin

E43 Medication:T68 

T69 Medication 1173 1176    S-1

E44 Medication:T69 

R46 MODIFY Arg1:E43 Arg2:E42    

R47 MODIFY Arg1:E44 Arg2:E42    

T70 Sign_symptom 1266 1295  gastrointestinal disturbances

E45 Sign_symptom:T70 

T71 Detailed_description 1205 1215  terminated

R48 MODIFY Arg1:E45 Arg2:T71    

R49 MODIFY Arg1:T71 Arg2:E42    

T72 Date 1300 1316  February 2, 2015

E46 Date:T72 

T73 Therapeutic_procedure 1318 1339 adjuvant radiotherapy

E47 Therapeutic_procedure:T73 

T74 Diagnostic_procedure 1379 1427  positron-emission tomography computed tomography

E48 Diagnostic_procedure:T74 

T75 Diagnostic_procedure 1429 1435  PET-CT

E49 Diagnostic_procedure:T75 

R50 IDENTICAL Arg1:E49 Arg2:E48 

T76 Severity 1444 1453  extensive

T77 Detailed_description 1454 1461  distant

T78 Disease_disorder 1462 1472  metastasis

E50 Disease_disorder:T78 

R51 MODIFY Arg1:T77 Arg2:E50    

R52 MODIFY Arg1:T76 Arg2:E50    

T79 Biological_structure 1511 1522  lymph nodes

T80 Biological_structure 1474 1494  left supraclavicular

T81 Biological_structure 1499 1510  mediastinal

R53 MODIFY Arg1:T81 Arg2:T79    

R54 MODIFY Arg1:T80 Arg2:T79    

T82 Biological_structure 1528 1539  lymph nodes

T83 Biological_structure 1555 1571  abdominal cavity

R55 MODIFY Arg1:T83 Arg2:T82    

R56 MODIFY Arg1:T79 Arg2:E50    

R57 MODIFY Arg1:T82 Arg2:E50    

T84 Diagnostic_procedure 1588 1622  Eastern Cooperative Oncology Group

E51 Diagnostic_procedure:T84 

T85 Diagnostic_procedure 1624 1628  ECOG

E52 Diagnostic_procedure:T85 

R58 IDENTICAL Arg1:E52 Arg2:E51 

T86 Lab_value 1653 1654 2

E53 Lab_value:T86 

R59 MODIFY Arg1:E53 Arg2:E51    

T87 Diagnostic_procedure 1664 1679  body mass index

E54 Diagnostic_procedure:T87 

T88 Diagnostic_procedure 1681 1684  BMI

E55 Diagnostic_procedure:T88 

R60 IDENTICAL Arg1:E55 Arg2:E54 

T89 Lab_value 1690 1692 19

E56 Lab_value:T89 

R61 MODIFY Arg1:E56 Arg2:E54    

T90 Sign_symptom 1740 1752  malnutrition

E57 Sign_symptom:T90 

A2  POLARITY E57 UNCERTAIN

T91 Administration 1754 1758    Oral

T92 Medication 1759 1767    apatinib

E58 Medication:T92 

T93 Dosage 1768 1774    850 mg

T94 Frequency 1775 1785 once a day

T95 Therapeutic_procedure 1814 1826 radiotherapy

E59 Therapeutic_procedure:T95 

R62 MODIFY Arg1:T91 Arg2:E58    

R63 MODIFY Arg1:T93 Arg2:E58    

R64 MODIFY Arg1:T94 Arg2:E58    

T96 Therapeutic_procedure 1970 2007 intensity modulated radiation therapy

E60 Therapeutic_procedure:T96 

T97 Therapeutic_procedure 2009 2013 IMRT

E61 Therapeutic_procedure:T97 

R65 IDENTICAL Arg1:E61 Arg2:E60 

T98 Detailed_description 1959 1969  palliative

R66 MODIFY Arg1:T98 Arg2:E60    

T99 Clinical_event 1831 1841    prescribed

E62 Clinical_event:T99 

R67 MODIFY Arg1:E58 Arg2:E62    

R68 MODIFY Arg1:E59 Arg2:E62    

T100    Dosage 2056 2077    64 Gy in 30 fractions

T101    Biological_structure 2085 2096  mediastinum

T102    Dosage 2110 2131    52 Gy in 26 fractions

T103    Disease_disorder 2155 2173  metastatic lesions

E63 Disease_disorder:T103 

T104    Biological_structure 2145 2154  abdominal

R69 MODIFY Arg1:T104 Arg2:E63   

R70 MODIFY Arg1:T100 Arg2:T101  

R71 MODIFY Arg1:T102 Arg2:T104  

T105    Biological_structure 2208 2218  lymph node

T106    Biological_structure 2187 2207  left supraclavicular

R72 MODIFY Arg1:T106 Arg2:T105  

T107    Medication 2236 2244    apatinib

E64 Medication:T107 

R73 MODIFY Arg1:E64 Arg2:T105   

R74 MODIFY Arg1:E60 Arg2:T100   

R75 MODIFY Arg1:E60 Arg2:T102   

T108    Diagnostic_procedure 2272 2278  PET-CT

E65 Diagnostic_procedure:T108 

T109    Date 2294 2320  2 weeks after radiotherapy

E66 Date:T109 

T110    Lab_value 2331 2344 80% reduction

E67 Lab_value:T110 

T111    Diagnostic_procedure 2352 2385  maximum standardized uptake value

E68 Diagnostic_procedure:T111 

T112    Diagnostic_procedure 2387 2393  SUVmax

E69 Diagnostic_procedure:T112 

R76 IDENTICAL Arg1:E69 Arg2:E68 

T113    Diagnostic_procedure 2398 2431  2-deoxy-2-[[18]F]fluoro-d-glucose

E70 Diagnostic_procedure:T113 

T114    Diagnostic_procedure 2433 2436  FDG

E71 Diagnostic_procedure:T114 

R77 IDENTICAL Arg1:E71 Arg2:E70 

R78 MODIFY Arg1:E70 Arg2:E68    

R79 MODIFY Arg1:E67 Arg2:E68    

T115    Diagnostic_procedure 2439 2449  FDG uptake

E72 Diagnostic_procedure:T115 

T116    Lab_value 2454 2460 higher

E73 Lab_value:T116 

T117    Biological_structure 2489 2499  lymph node

T118    Biological_structure 2468 2488  left supraclavicular

R80 MODIFY Arg1:T118 Arg2:T117  

R81 MODIFY Arg1:E73 Arg2:E72    

R82 MODIFY Arg1:T117 Arg2:E72   

T119    Biological_structure 2516 2534  metastatic regions

T120    Medication 2559 2567    apatinib

E74 Medication:T120 

T121    Therapeutic_procedure 2572 2589 radiation therapy

E75 Therapeutic_procedure:T121 

T122    Diagnostic_procedure 2604 2648  Response Evaluation Criteria in Solid Tumors

E76 Diagnostic_procedure:T122 

R83 MODIFY Arg1:E74 Arg2:T119   

R84 MODIFY Arg1:E75 Arg2:T119   

T123    Diagnostic_procedure 2650 2656  RECIST

E77 Diagnostic_procedure:T123 

R85 IDENTICAL Arg1:E77 Arg2:E76 

T124    Lab_value 2683 2699 partial response

E78 Lab_value:T124 

R86 MODIFY Arg1:E78 Arg2:E76    

T125    Therapeutic_procedure 2738 2750 radiotherapy

E79 Therapeutic_procedure:T125 

T126    Dosage 2752 2773    66 Gy in 28 fractions

R87 MODIFY Arg1:T126 Arg2:E79   

T127    Biological_structure 2803 2813  lymph node

T128    Biological_structure 2782 2802  left supraclavicular

R88 MODIFY Arg1:T128 Arg2:T127  

T129    Disease_disorder 2821 2840  residual metastasis

E80 Disease_disorder:T129 

R89 CAUSE Arg1:E80 Arg2:E79 

R90 MODIFY Arg1:T127 Arg2:E79   

T130    Diagnostic_procedure 2842 2855  Tumor markers

E81 Diagnostic_procedure:T130 

T131    Diagnostic_procedure 2860 2880  biochemical analyses

E82 Diagnostic_procedure:T131 

T132    Frequency 2896 2910 every 2 months

R91 MODIFY Arg1:T132 Arg2:E82   

R92 MODIFY Arg1:T132 Arg2:E81   

T133    Date 2912 2936  Two months after therapy

E83 Date:T133 

T134    Diagnostic_procedure 2959 2967  CT scans

E84 Diagnostic_procedure:T134 

T135    Biological_structure 2938 2943  chest

T136    Biological_structure 2949 2958  abdominal

R93 MODIFY Arg1:T136 Arg2:E84   

R94 MODIFY Arg1:T135 Arg2:E84   

T137    Disease_disorder 2985 2992  disease

E85 Disease_disorder:T137 

T138    Detailed_description 2978 2984  stable

R95 MODIFY Arg1:T138 Arg2:E85   

T139    Sign_symptom 2994 3000  anemia

E86 Sign_symptom:T139 

T140    Sign_symptom 3005 3030  gastrointestinal symptoms

E87 Sign_symptom:T140 

T141    Qualitative_concept 3035 3043   improved

R96 MODIFY Arg1:T141 Arg2:E87   

R97 MODIFY Arg1:T141 Arg2:E86   

T142    Diagnostic_procedure 3045 3049  ECOG

E88 Diagnostic_procedure:T142 

T143    Diagnostic_procedure 3080 3083  BMI

E89 Diagnostic_procedure:T143 

T144    Lab_value 3073 3074 0

E90 Lab_value:T144 

T145    Lab_value 3088 3090 22

E91 Lab_value:T145 

R98 MODIFY Arg1:E90 Arg2:E88    

R99 MODIFY Arg1:E91 Arg2:E89    

T146    Sign_symptom 3092 3112  Hematologic toxicity

E92 Sign_symptom:T146 

A3  POLARITY E92 NEG

T147    Sign_symptom 3114 3126  hypertension

E93 Sign_symptom:T147 

A4  POLARITY E93 NEG

T148    Sign_symptom 3128 3145  renal dysfunction

E94 Sign_symptom:T148 

A5  POLARITY E94 NEG

T149    Sign_symptom 3147 3158  proteinuria

E95 Sign_symptom:T149 

A6  POLARITY E95 NEG

T150    Sign_symptom 3164 3182  hand–foot syndrome

E96 Sign_symptom:T150 

A7  POLARITY E96 NEG

T151    Medication 3208 3216    apatinib

E97 Medication:T151 

T152    Date 3229 3243  September 2015

E98 Date:T152 

T153    Diagnostic_procedure 3247 3268  follow-up examination

E99 Diagnostic_procedure:T153 

T154    Lab_value 3276 3285 increased

E100    Lab_value:T154 

T155    Diagnostic_procedure 3286 3315  carbohydrate antigen (CA) 125

E101    Diagnostic_procedure:T155 

T156    Diagnostic_procedure 3320 3328  ferritin

E102    Diagnostic_procedure:T156 

T157    Diagnostic_procedure 3339 3350  gastroscopy

E103    Diagnostic_procedure:T157 

T158    Diagnostic_procedure 3365 3367  CT

E104    Diagnostic_procedure:T158 

T159    Biological_structure 3355 3364  abdominal

R100    MODIFY Arg1:E100 Arg2:E101  

R101    MODIFY Arg1:E100 Arg2:E102  

R102    MODIFY Arg1:T159 Arg2:E104  

T160    Sign_symptom 3380 3393  abnormalities

E105    Sign_symptom:T160 

A8  POLARITY E105 NEG

R103    MODIFY Arg1:E105 Arg2:E104  

R104    MODIFY Arg1:E105 Arg2:E103  

T161    Date 3398 3411  November 2015

E106    Date:T161 

T162    Sign_symptom 3429 3450  difficulty swallowing

E107    Sign_symptom:T162 

T163    Sign_symptom 3480 3492  hematochezia

E108    Sign_symptom:T163 

T164    Detailed_description 3467 3479  intermittent

R105    MODIFY Arg1:T164 Arg2:E108  

T165    Diagnostic_procedure 3552 3563  Gastroscopy

E109    Diagnostic_procedure:T165 

T166    Medication 3494 3502    Apatinib

E110    Medication:T166 

T167    Sign_symptom 3525 3550  gastrointestinal bleeding

E111    Sign_symptom:T167 

T168    Detailed_description 3507 3517  terminated

R106    MODIFY Arg1:T168 Arg2:E110  

R107    CAUSE Arg1:E111 Arg2:T168   

T169    Sign_symptom 3573 3593  anastomotic stenosis

E112    Sign_symptom:T169 

T170    Disease_disorder 3601 3615  gastric cancer

E113    Disease_disorder:T170 

T171    Disease_disorder 3620 3642  intragastric hemorrhag

E114    Disease_disorder:T171 

R108    CAUSE Arg1:E113 Arg2:E112   

R109    CAUSE Arg1:E114 Arg2:E112   

T172    Therapeutic_procedure 3691 3708 chemoradiotherapy

E115    Therapeutic_procedure:T172 

A9  POLARITY E115 NEG

T173    Medication 3739 3754    hemostatic drug

E116    Medication:T173 

T174    Therapeutic_procedure 3764 3779 supportive care

E117    Therapeutic_procedure:T174 

T175    Date 3797 3809  After 1 week

E118    Date:T175 

T176    Disease_disorder 3822 3834  hemorrhaging

E119    Disease_disorder:T176 

A10 POLARITY E119 NEG

T177    Date 3849 3865  One month later,

E120    Date:T177 

T178    Detailed_description 3896 3908  intermittent

T179    Sign_symptom 3909 3921  hematochezia

E121    Sign_symptom:T179 

R110    MODIFY Arg1:T178 Arg2:E121  

T180    Date 3926 3943  December 20, 2015

E122    Date:T180 

T181    Diagnostic_procedure 3945 3951  PET-CT

E123    Diagnostic_procedure:T181 

T182    Disease_disorder 3975 3985  metastasis

E124    Disease_disorder:T182 

T183    Severity 3965 3974  extensive

R111    MODIFY Arg1:T183 Arg2:E124  

T184    Therapeutic_procedure 4029 4044 supportive care

E125    Therapeutic_procedure:T184 

T185    Date 4049 4063  April 16, 2016

E126    Date:T185 

T186    Outcome 4077 4081   died

E127    Outcome:T186 

T187    Disease_disorder 4099 4108  infection

E128    Disease_disorder:T187 

T188    Biological_structure 4089 4098  pulmonary

R112    MODIFY Arg1:T188 Arg2:E128  

*   OVERLAP E1 E2 E3 E4 E129

T189    Clinical_event 97 105   referred

E129    Clinical_event:T189 

R113    MODIFY Arg1:T8 Arg2:E129    

R114    BEFORE Arg1:E129 Arg2:E5    

*   OVERLAP E5 E6 E7 E8 E9

R115    BEFORE Arg1:E9 Arg2:E10 

*   OVERLAP E10 E11 E13 E14

R116    BEFORE Arg1:E14 Arg2:E15    

*   OVERLAP E15 E16 E17 E40 E41

R117    BEFORE Arg1:E41 Arg2:E42    

R118    BEFORE Arg1:E42 Arg2:E46    

*   OVERLAP E46 E47 E48 E50

R119    BEFORE Arg1:E50 Arg2:E51    

*   OVERLAP E51 E54 E57 E62

R120    BEFORE Arg1:E62 Arg2:E60    

*   OVERLAP E60 E64

R121    BEFORE Arg1:E64 Arg2:E65    

*   OVERLAP E65 E66 E68 E72 E74 E76

R122    BEFORE Arg1:E76 Arg2:E79    

R123    BEFORE Arg1:E79 Arg2:E81    

*   OVERLAP E81 E82

R124    BEFORE Arg1:E82 Arg2:E83    

*   OVERLAP E83 E84 E85 E86 E87 E88 E89 E97

R125    CAUSE Arg1:E97 Arg2:E96 

R126    CAUSE Arg1:E97 Arg2:E95 

R127    CAUSE Arg1:E97 Arg2:E94 

R128    CAUSE Arg1:E97 Arg2:E93 

R129    CAUSE Arg1:E97 Arg2:E92 

R130    BEFORE Arg1:E97 Arg2:E98    

*   OVERLAP E98 E99 E101 E102 E103 E104

R131    BEFORE Arg1:E104 Arg2:E106  

*   OVERLAP E106 E107 E108 E110 E109 E112 E115 E130

T190    Clinical_event 3785 3795    prescribed

E130    Clinical_event:T190 

R132    MODIFY Arg1:E130 Arg2:E117  

R133    MODIFY Arg1:E130 Arg2:E116  

R134    BEFORE Arg1:E130 Arg2:E118  

*   OVERLAP E118 E119

R135    BEFORE Arg1:E119 Arg2:E120  

*   OVERLAP E120 E121

R136    BEFORE Arg1:E121 Arg2:E122  

*   OVERLAP E122 E123 E124 E125

R137    BEFORE Arg1:E125 Arg2:E126  

*   OVERLAP E126 E127 E128