Downloads: 1
458 lines (457 with data), 15.8 kB
T1 Age 2 13 73-year-old T2 Sex 14 17 man T3 History 46 88 type 2 diabetes mellitus at 35 year of age T4 Date 208 217 first day E1 Date:T4 T5 Clinical_event 235 242 visited E2 Clinical_event:T5 T6 Nonbiological_location 247 261 emergency room R1 MODIFY Arg1:T6 Arg2:E2 T7 Sign_symptom 157 177 respiratory distress E3 Sign_symptom:T7 T8 Sign_symptom 195 199 pain E4 Sign_symptom:T8 T9 Biological_structure 189 194 chest R2 MODIFY Arg1:T9 Arg2:E4 T10 Detailed_description 182 188 sudden R3 MODIFY Arg1:T10 Arg2:E4 T11 Diagnostic_procedure 265 285 physical examination E5 Diagnostic_procedure:T11 T12 Clinical_event 3662 3666 died E6 Clinical_event:T12 T13 Date 3604 3610 day 87 E7 Date:T13 T14 Disease_disorder 3612 3636 ventricular fibrillation E8 Disease_disorder:T14 T15 Diagnostic_procedure 3668 3675 Autopsy E9 Diagnostic_procedure:T15 A1 POLARITY E9 NEG T16 Diagnostic_procedure 304 320 body temperature E10 Diagnostic_procedure:T16 T17 Lab_value 325 331 35.4°C R4 MODIFY Arg1:T17 Arg2:E10 T18 Diagnostic_procedure 337 347 heart rate E11 Diagnostic_procedure:T18 T19 Lab_value 352 364 90 beats/min T20 Lab_value 372 386 regular rhythm R5 MODIFY Arg1:T19 Arg2:E11 R6 MODIFY Arg1:T20 Arg2:E11 T21 Diagnostic_procedure 396 410 blood pressure E12 Diagnostic_procedure:T21 T22 Lab_value 415 426 130/77 mmHg R7 MODIFY Arg1:T22 Arg2:E12 R8 SUB_PROCEDURE Arg1:E10 Arg2:E5 R9 SUB_PROCEDURE Arg1:E11 Arg2:E5 R10 SUB_PROCEDURE Arg1:E12 Arg2:E5 T23 Diagnostic_procedure 430 450 physical examination E13 Diagnostic_procedure:T23 T24 Sign_symptom 467 475 crackles E14 Sign_symptom:T24 T25 Detailed_description 460 466 coarse R11 MODIFY Arg1:T25 Arg2:E14 T26 Diagnostic_procedure 489 506 lung auscultation E15 Diagnostic_procedure:T26 R12 SUB_PROCEDURE Arg1:E15 Arg2:E13 T27 Detailed_description 479 488 bilateral R13 MODIFY Arg1:T27 Arg2:E15 T28 Diagnostic_procedure 512 527 laboratory data E16 Diagnostic_procedure:T28 T29 Diagnostic_procedure 537 540 WBC E17 Diagnostic_procedure:T29 T30 Lab_value 550 558 8,800/μL R14 MODIFY Arg1:T30 Arg2:E17 T31 Diagnostic_procedure 585 596 neutrophils E18 Diagnostic_procedure:T31 T32 Lab_value 566 583 shift to the left R15 MODIFY Arg1:T32 Arg2:E17 T33 Lab_value 597 600 82% R16 MODIFY Arg1:T33 Arg2:E18 R17 SUB_PROCEDURE Arg1:E17 Arg2:E16 R18 SUB_PROCEDURE Arg1:E18 Arg2:E17 T34 Diagnostic_procedure 603 605 Hb E19 Diagnostic_procedure:T34 T35 Lab_value 606 615 10.2 g/dL R19 MODIFY Arg1:T35 Arg2:E19 T36 Diagnostic_procedure 617 636 blood urea nitrogen E20 Diagnostic_procedure:T36 T37 Diagnostic_procedure 638 641 BUN E21 Diagnostic_procedure:T37 R20 IDENTICAL Arg1:E21 Arg2:E20 R21 SUB_PROCEDURE Arg1:E19 Arg2:E16 R22 SUB_PROCEDURE Arg1:E20 Arg2:E16 T38 Lab_value 643 653 82.2 mg/dL R23 MODIFY Arg1:T38 Arg2:E20 T39 Diagnostic_procedure 655 665 creatinine E22 Diagnostic_procedure:T39 T40 Diagnostic_procedure 667 670 Cre E23 Diagnostic_procedure:T40 R24 IDENTICAL Arg1:E23 Arg2:E22 T41 Lab_value 672 682 6.50 mg/dL R25 MODIFY Arg1:T41 Arg2:E22 T42 Diagnostic_procedure 684 689 HbA1c E24 Diagnostic_procedure:T42 T43 Lab_value 690 694 5.9% R26 MODIFY Arg1:T43 Arg2:E24 R27 SUB_PROCEDURE Arg1:E22 Arg2:E16 R28 SUB_PROCEDURE Arg1:E24 Arg2:E16 T44 Diagnostic_procedure 696 711 creatine kinase E25 Diagnostic_procedure:T44 T45 Diagnostic_procedure 713 715 CK E26 Diagnostic_procedure:T45 T46 Lab_value 717 725 189 IU/L R29 MODIFY Arg1:T46 Arg2:E25 R30 IDENTICAL Arg1:E26 Arg2:E25 R31 SUB_PROCEDURE Arg1:E25 Arg2:E16 T47 Diagnostic_procedure 727 745 C-reactive protein E27 Diagnostic_procedure:T47 T48 Diagnostic_procedure 747 750 CRP E28 Diagnostic_procedure:T48 R32 IDENTICAL Arg1:E28 Arg2:E27 T49 Lab_value 752 762 8.51 mg/dL R33 MODIFY Arg1:T49 Arg2:E28 R34 SUB_PROCEDURE Arg1:E27 Arg2:E16 T50 Diagnostic_procedure 764 794 brain-type natriuretic peptide E29 Diagnostic_procedure:T50 T51 Diagnostic_procedure 796 799 BNP E30 Diagnostic_procedure:T51 R35 IDENTICAL Arg1:E30 Arg2:E29 T52 Lab_value 801 812 127.4 pg/mL R36 MODIFY Arg1:T52 Arg2:E29 R37 SUB_PROCEDURE Arg1:E29 Arg2:E16 T53 Diagnostic_procedure 822 832 radiograph E31 Diagnostic_procedure:T53 T54 Biological_structure 816 821 chest R38 MODIFY Arg1:T54 Arg2:E31 T55 Sign_symptom 852 866 consolidations E32 Sign_symptom:T55 T56 Detailed_description 842 851 perihilar R39 MODIFY Arg1:T56 Arg2:E32 T57 Sign_symptom 875 887 bronchograms E33 Sign_symptom:T57 T58 Detailed_description 871 874 air R40 MODIFY Arg1:T58 Arg2:E33 T59 Diagnostic_procedure 900 917 electrocardiogram E34 Diagnostic_procedure:T59 T60 Sign_symptom 927 947 ST-segment elevation E35 Sign_symptom:T60 T61 Sign_symptom 952 975 poor R-wave progression E36 Sign_symptom:T61 T62 Detailed_description 979 990 leads V1-V3 R41 MODIFY Arg1:T62 Arg2:E36 T63 Diagnostic_procedure 996 1012 echocardiography E37 Diagnostic_procedure:T63 T64 Sign_symptom 1022 1053 apical and ventricular asynergy E38 Sign_symptom:T64 T65 Disease_disorder 1102 1123 myocardial infarction E39 Disease_disorder:T65 T66 Detailed_description 1096 1101 acute R42 MODIFY Arg1:T66 Arg2:E39 T67 Disease_disorder 1139 1152 heart failure E40 Disease_disorder:T67 T68 Detailed_description 1128 1138 congestive R43 MODIFY Arg1:T68 Arg2:E40 T69 Diagnostic_procedure 1163 1174 angiography E41 Diagnostic_procedure:T69 T70 Biological_structure 1154 1162 Coronary R44 MODIFY Arg1:T70 Arg2:E41 T71 Sign_symptom 1207 1220 angiostenosis E42 Sign_symptom:T71 T72 Biological_structure 1228 1241 septal branch R45 MODIFY Arg1:T72 Arg2:E42 T73 Therapeutic_procedure 1243 1246 PCI E43 Therapeutic_procedure:T73 #1 AnnotatorNotes E43 percutaneous coronary intervention T74 Therapeutic_procedure 1316 1324 dialysis E44 Therapeutic_procedure:T74 T75 Detailed_description 1304 1315 maintenance T76 Detailed_description 1293 1303 continuous R46 MODIFY Arg1:T75 Arg2:E44 R47 MODIFY Arg1:T76 Arg2:E44 T77 Date 1333 1346 following day E45 Date:T77 T78 Disease_disorder 1370 1394 cardiorespiratory arrest E46 Disease_disorder:T78 T79 Therapeutic_procedure 1399 1428 cardiopulmonary resuscitation E47 Therapeutic_procedure:T79 T80 Therapeutic_procedure 1467 1478 ventilation E48 Therapeutic_procedure:T80 T81 Detailed_description 1456 1466 mechanical R48 MODIFY Arg1:T81 Arg2:E48 T82 Date 1483 1488 day 8 E49 Date:T82 T83 Therapeutic_procedure 1490 1500 ventilator E50 Therapeutic_procedure:T83 A2 POLARITY E50 NEG T84 Sign_symptom 1584 1590 sputum E51 Sign_symptom:T84 T85 Lab_value 1563 1580 increasing volume R49 MODIFY Arg1:T85 Arg2:E51 T86 Lab_value 1614 1622 purulent R50 MODIFY Arg1:T86 Arg2:E51 T87 Sign_symptom 1624 1646 Pseudomonas aeruginosa E52 Sign_symptom:T87 T88 Diagnostic_procedure 1669 1683 sputum culture E53 Diagnostic_procedure:T88 T89 Medication 1689 1712 tazobactam/piperacillin E54 Medication:T89 T90 Medication 1714 1722 TAZ/PIPC E55 Medication:T90 R51 IDENTICAL Arg1:E55 Arg2:E54 T91 Dosage 1725 1734 4.5g q12h R52 MODIFY Arg1:T91 Arg2:E54 T92 Diagnostic_procedure 1790 1811 respiratory condition E56 Diagnostic_procedure:T92 T93 Lab_value 1812 1820 worsened R53 MODIFY Arg1:T93 Arg2:E56 T94 Diagnostic_procedure 1833 1852 computed tomography E57 Diagnostic_procedure:T94 T95 Biological_structure 1827 1832 chest R54 MODIFY Arg1:T95 Arg2:E57 T96 Diagnostic_procedure 1854 1856 CT E58 Diagnostic_procedure:T96 R55 IDENTICAL Arg1:E58 Arg2:E57 T97 Date 1866 1872 day 15 E59 Date:T97 T98 Sign_symptom 1902 1911 opacities E60 Sign_symptom:T98 T99 Disease_disorder 1913 1929 pleural effusion E61 Disease_disorder:T99 T100 Disease_disorder 1935 1946 atelectasis E62 Disease_disorder:T100 T101 Detailed_description 1892 1901 perihilar T102 Detailed_description 1882 1891 bilateral R56 MODIFY Arg1:T101 Arg2:E60 R57 MODIFY Arg1:T102 Arg2:E60 T103 Diagnostic_procedure 2067 2083 sputum culturing E63 Diagnostic_procedure:T103 T104 Diagnostic_procedure 2088 2108 serum fungal antigen E64 Diagnostic_procedure:T104 T105 Disease_disorder 2034 2047 pneumomycosis E65 Disease_disorder:T105 A3 POLARITY E65 UNCERTAIN T106 Disease_disorder 2010 2032 microbial substitution E66 Disease_disorder:T106 A4 POLARITY E66 UNCERTAIN T107 Medication 2138 2146 TAZ/PIPC E67 Medication:T107 A5 POLARITY E67 NEG T108 Medication 2162 2171 meropenem E68 Medication:T108 T109 Dosage 2173 2182 0.5 g/day R58 MODIFY Arg1:T109 Arg2:E68 T110 Date 2188 2194 day 16 E69 Date:T110 T111 Diagnostic_procedure 2210 2215 serum E70 Diagnostic_procedure:T111 T112 Diagnostic_procedure 2236 2256 Cryptococcus antigen E71 Diagnostic_procedure:T112 R59 SUB_PROCEDURE Arg1:E71 Arg2:E70 T113 Lab_value 2223 2231 positive R60 MODIFY Arg1:T113 Arg2:E71 T114 Date 2261 2267 day 21 E72 Date:T114 T115 Diagnostic_procedure 2320 2334 blood cultures E73 Diagnostic_procedure:T115 T116 Detailed_description 2308 2316 two sets R61 MODIFY Arg1:T116 Arg2:E73 T117 Sign_symptom 2269 2288 cryptococcal bodies E74 Sign_symptom:T117 T118 Medication 2339 2363 liposomal amphotericin B E75 Medication:T118 T119 Medication 2365 2370 L-AMB E76 Medication:T119 R62 IDENTICAL Arg1:E76 Arg2:E75 T120 Dosage 2373 2384 3 mg/kg/day R63 MODIFY Arg1:T120 Arg2:E75 T121 Date 2407 2413 day 23 E77 Date:T121 T122 Sign_symptom 2415 2434 cryptococcal bodies E78 Sign_symptom:T122 T123 Diagnostic_procedure 2458 2464 sputum E79 Diagnostic_procedure:T123 T124 Diagnostic_procedure 2466 2485 cerebrospinal fluid E80 Diagnostic_procedure:T124 T125 Diagnostic_procedure 2501 2517 pleural effusion E81 Diagnostic_procedure:T125 #2 AnnotatorNotes E81 this is a test of the fluid in the lungs, but also indicates the condition is still present T126 Disease_disorder 2501 2517 pleural effusion E82 Disease_disorder:T126 T127 Detailed_description 2491 2500 bilateral R64 MODIFY Arg1:T127 Arg2:E82 T128 Disease_disorder 2581 2595 cryptococcosis E83 Disease_disorder:T128 T129 Detailed_description 2568 2580 disseminated R65 MODIFY Arg1:T129 Arg2:E83 T130 Date 2600 2606 day 25 E84 Date:T130 T131 Diagnostic_procedure 2614 2616 CT E85 Diagnostic_procedure:T131 T132 Biological_structure 2608 2613 brain R66 MODIFY Arg1:T132 Arg2:E85 T133 Sign_symptom 2654 2666 hypertension E86 Sign_symptom:T133 A6 POLARITY E86 NEG T134 Biological_structure 2641 2653 intracranial R67 MODIFY Arg1:T134 Arg2:E86 T135 Disease_disorder 2679 2686 abscess E87 Disease_disorder:T135 T136 Biological_structure 2673 2678 brain R68 MODIFY Arg1:T136 Arg2:E87 T137 Disease_disorder 2722 2750 human immunodeficiency virus E88 Disease_disorder:T137 A7 POLARITY E88 NEG T138 Disease_disorder 2752 2755 HIV E89 Disease_disorder:T138 A8 POLARITY E89 NEG R69 IDENTICAL Arg1:E89 Arg2:E88 T139 Medication 2780 2785 L-AMB E90 Medication:T139 T140 Dosage 2787 2798 3 mg/kg/day R70 MODIFY Arg1:T140 Arg2:E90 T141 Date 2818 2824 day 31 E91 Date:T141 T142 Diagnostic_procedure 2832 2834 CT E92 Diagnostic_procedure:T142 T143 Biological_structure 2826 2831 chest R71 MODIFY Arg1:T143 Arg2:E92 T144 Sign_symptom 2855 2861 nodule E93 Sign_symptom:T144 T145 Detailed_description 2846 2854 solitary R72 MODIFY Arg1:T145 Arg2:E93 T146 Biological_structure 2869 2890 left lingular segment R73 MODIFY Arg1:T146 Arg2:E93 T147 Disease_disorder 2949 2968 cryptococcus lesion E94 Disease_disorder:T147 A9 POLARITY E94 UNCERTAIN T148 Biological_structure 2939 2948 pulmonary R74 MODIFY Arg1:T148 Arg2:E94 T149 Date 2979 2997 After several days E95 Date:T149 T150 Diagnostic_procedure 3071 3085 fluid cultures E96 Diagnostic_procedure:T150 T151 Detailed_description 3025 3034 bilateral T155 Lab_value 3093 3101 negative R80 MODIFY Arg1:T155 Arg2:E96 T156 Disease_disorder 3035 3051 pleural effusion E97 Disease_disorder:T156 R75 MODIFY Arg1:T151 Arg2:E97 T152 Diagnostic_procedure 3018 3023 blood E98 Diagnostic_procedure:T152 T153 Diagnostic_procedure 3010 3016 sputum E99 Diagnostic_procedure:T153 T154 Diagnostic_procedure 3035 3051 pleural effusion E100 Diagnostic_procedure:T154 T157 Diagnostic_procedure 3057 3070 cerebrospinal E101 Diagnostic_procedure:T157 R76 SUB_PROCEDURE Arg1:E101 Arg2:E96 R77 SUB_PROCEDURE Arg1:E100 Arg2:E96 R78 SUB_PROCEDURE Arg1:E98 Arg2:E96 R79 SUB_PROCEDURE Arg1:E99 Arg2:E96 T158 Date 3106 3112 day 52 E102 Date:T158 T159 Diagnostic_procedure 3120 3122 CT E103 Diagnostic_procedure:T159 T160 Sign_symptom 3145 3151 nodule E104 Sign_symptom:T160 T161 Biological_structure 3140 3144 lung R81 MODIFY Arg1:T161 Arg2:E104 T162 Biological_structure 3114 3119 chest R82 MODIFY Arg1:T162 Arg2:E103 T163 Biological_structure 3159 3188 right pulmonary apical region R83 MODIFY Arg1:T163 Arg2:E104 T164 Sign_symptom 3196 3203 nodules E105 Sign_symptom:T164 A10 TREND E105 DEC T165 Date 3238 3244 day 79 E106 Date:T165 T166 Lab_value 3214 3231 decreased in size R84 MODIFY Arg1:T166 Arg2:E105 T167 Medication 3270 3275 L-AMB E107 Medication:T167 T168 Diagnostic_procedure 3306 3324 C-reactive protein E108 Diagnostic_procedure:T168 T169 Lab_value 3340 3348 elevated R85 MODIFY Arg1:T169 Arg2:E108 T170 Disease_disorder 3367 3383 pleural effusion E109 Disease_disorder:T170 A11 TREND E109 INC T171 Detailed_description 3357 3366 bilateral R86 MODIFY Arg1:T171 Arg2:E109 T172 Sign_symptom 3420 3438 lost consciousness E110 Sign_symptom:T172 T173 Diagnostic_procedure 3460 3474 vital capacity E111 Diagnostic_procedure:T173 T174 Lab_value 3450 3459 decreased R87 MODIFY Arg1:T174 Arg2:E111 T175 Disease_disorder 3501 3517 pleural effusion E112 Disease_disorder:T175 A12 TREND E112 INC T176 Detailed_description 3491 3500 bilateral R88 MODIFY Arg1:T176 Arg2:E112 T177 Disease_disorder 3541 3553 CO2 narcosis E113 Disease_disorder:T177 T178 Diagnostic_procedure 3569 3586 general condition E114 Diagnostic_procedure:T178 T179 Lab_value 3587 3599 deteriorated R89 MODIFY Arg1:T179 Arg2:E114 T180 Diagnostic_procedure 3824 3840 genetic analysis E115 Diagnostic_procedure:T180 T181 Detailed_description 3716 3736 Cryptococcus isolate R90 MODIFY Arg1:T181 Arg2:E115 T182 Disease_disorder 3770 3818 Cryptococcus neoformans var. grubii (serotype A) E116 Disease_disorder:T182 * OVERLAP E1 E2 E3 E4 E5 E13 E14 E16 E31 E32 E33 E34 E35 E36 E37 E38 E39 E40 R91 BEFORE Arg1:E40 Arg2:E41 * OVERLAP E41 E42 E43 E44 R92 BEFORE Arg1:E44 Arg2:E45 * OVERLAP E45 E46 R93 BEFORE Arg1:E47 Arg2:E48 R94 BEFORE Arg1:E48 Arg2:E49 * OVERLAP E49 E50 E51 E52 E53 E54 R95 BEFORE Arg1:E54 Arg2:E56 * OVERLAP E56 E57 E59 E60 E61 E62 E66 E65 E63 E64 E67 E68 R96 BEFORE Arg1:E68 Arg2:E69 * OVERLAP E69 E70 R97 BEFORE Arg1:E70 Arg2:E72 * OVERLAP E72 E74 E73 E75 R98 BEFORE Arg1:E75 Arg2:E77 * OVERLAP E77 E78 E79 E80 E81 E82 E83 R99 BEFORE Arg1:E83 Arg2:E84 * OVERLAP E84 E85 E86 E87 E88 E90 R100 BEFORE Arg1:E90 Arg2:E91 * OVERLAP E91 E92 E93 E94 R101 BEFORE Arg1:E94 Arg2:E95 * OVERLAP E95 E97 E96 R102 BEFORE Arg1:E96 Arg2:E102 * OVERLAP E102 E103 E104 R103 BEFORE Arg1:E104 Arg2:E105 R104 BEFORE Arg1:E105 Arg2:E106 * OVERLAP E106 E107 E108 E109 R105 BEFORE Arg1:E109 Arg2:E110 * OVERLAP E110 E111 E112 R106 BEFORE Arg1:E112 Arg2:E113 R107 BEFORE Arg1:E113 Arg2:E114 R108 BEFORE Arg1:E114 Arg2:E7 * OVERLAP E7 E8 E6 R109 BEFORE Arg1:E6 Arg2:E9 R110 BEFORE Arg1:E9 Arg2:E117 * OVERLAP E116 E115 E117 T183 Date 3695 3710 At a later date E117 Date:T183 T184 Date 74 88 35 year of age E118 Date:T184 T185 History 98 124 severe diabetic neuropathy T186 History 129 142 diabetic-ESRD T187 Disease_disorder 46 70 type 2 diabetes mellitus E119 Disease_disorder:T187 * OVERLAP E119 E118 T188 Disease_disorder 105 124 diabetic neuropathy E120 Disease_disorder:T188 T189 Severity 98 104 severe R111 MODIFY Arg1:T189 Arg2:E120 T190 Disease_disorder 129 142 diabetic-ESRD E121 Disease_disorder:T190 #3 AnnotatorNotes E121 diabetic end-stage renal disease R112 BEFORE Arg1:E118 Arg2:E120 * OVERLAP E120 E121 R113 BEFORE Arg1:E121 Arg2:E3