171 lines (170 with data), 5.3 kB

T1	Disease_disorder 135 140	NSCLC
E1	Disease_disorder:T1 
#1	AnnotatorNotes E1	Non-small cell lung cancer
T2	Detailed_description 126 134	squamous
R1	MODIFY Arg1:T2 Arg2:E1	
T3	Detailed_description 106 116	Stage IIIB
T4	Detailed_description 118 124	T4N2M0
R2	MODIFY Arg1:T4 Arg2:E1	
R3	MODIFY Arg1:T3 Arg2:E1	
T5	Age 2 13	68-year-old
T6	Sex 14 20	female
T7	History 21 27	smoker
T8	History 46 64	pulmonary embolism
T9	History 69 86	diabetes mellitus
T10	Therapeutic_procedure 172 189	chemoradiotherapy
E2	Therapeutic_procedure:T10 
T11	Detailed_description 161 171	definitive
R4	MODIFY Arg1:T11 Arg2:E2	
T12	Medication 195 204	cisplatin
E3	Medication:T12 
T13	Medication 209 220	vinorelbine
E4	Medication:T13 
R5	SUB_PROCEDURE Arg1:E3 Arg2:E2	
R6	SUB_PROCEDURE Arg1:E4 Arg2:E2	
T14	Date 221 241	until September 2014
E5	Date:T14 
T15	Date 243 258	In October 2014
E6	Date:T15 
T16	Diagnostic_procedure 260 308	positron emission tomography–computed tomography
E7	Diagnostic_procedure:T16 
T17	Diagnostic_procedure 309 317	(PET-CT)
E8	Diagnostic_procedure:T17 
R7	IDENTICAL Arg1:E8 Arg2:E7	
T18	Lab_value 338 351	good response
R8	MODIFY Arg1:T18 Arg2:E7	
T19	Biological_structure 359 373	primary lesion
R9	MODIFY Arg1:T19 Arg2:T18	
T20	Sign_symptom 388 398	metastases
E9	Sign_symptom:T20 
T21	Biological_structure 406 425	right adrenal gland
R10	MODIFY Arg1:T21 Arg2:E9	
T22	Biological_structure 430 441	right femur
R11	MODIFY Arg1:T22 Arg2:E9	
T23	Therapeutic_procedure 461 471	irradiated
E10	Therapeutic_procedure:T23 
T24	Date 472 488	in November 2014
E11	Date:T24 
T25	Sign_symptom 578 588	metastases
E12	Sign_symptom:T25 
T26	Date 490 503	A month later
E13	Date:T26 
T27	Biological_structure 565 577	subcutaneous
T28	Detailed_description 547 555	multiple
T29	Biological_structure 556 560	bone
R12	MODIFY Arg1:T27 Arg2:E12	
R13	MODIFY Arg1:T29 Arg2:E12	
R14	MODIFY Arg1:T28 Arg2:E12	
T30	Sign_symptom 638 645	dyspnea
E14	Sign_symptom:T30 
T31	Therapeutic_procedure 654 670	oxygen-dependent
E15	Therapeutic_procedure:T31 
T32	Severity 631 637	severe
R15	MODIFY Arg1:T32 Arg2:E14	
T33	Dosage 685 694	one cycle
T34	Medication 698 709	carboplatin
E16	Medication:T34 
T35	Medication 714 725	gemcitabine
E17	Medication:T35 
T36	Severity 738 744	severe
T37	Sign_symptom 745 757	pancytopenia
E18	Sign_symptom:T37 
R16	MODIFY Arg1:T36 Arg2:E18	
R17	MODIFY Arg1:T33 Arg2:E16	
R18	MODIFY Arg1:T33 Arg2:E17	
T38	Medication 789 798	nivolumab
E19	Medication:T38 
T39	Dosage 799 815	3 mg/kg q14 days
R19	MODIFY Arg1:T39 Arg2:E19	
T40	Date 816 831	in January 2015
E20	Date:T40 
T41	Date 833 876	One week after the first cycle of nivolumab
E21	Date:T41 
T42	Medication 867 876	nivolumab
E22	Medication:T42 
T43	Sign_symptom 893 899	lesion
E23	Sign_symptom:T43 
T44	Biological_structure 880 892	subcutaneous
R20	MODIFY Arg1:T44 Arg2:E23	
T45	Biological_structure 907 917	upper back
R21	MODIFY Arg1:T45 Arg2:E23	
T46	Detailed_description 918 936	grew substantially
R22	MODIFY Arg1:T46 Arg2:E23	
T47	Sign_symptom 960 964	pain
E24	Sign_symptom:T47 
T48	Sign_symptom 981 1002	inflammatory reaction
E25	Sign_symptom:T48 
T49	Severity 953 959	severe
T50	Severity 969 980	significant
R23	MODIFY Arg1:T50 Arg2:E25	
R24	MODIFY Arg1:T49 Arg2:E24	
T51	Sign_symptom 1031 1041	metastases
E26	Sign_symptom:T51 
T52	Biological_structure 1018 1030	subcutaneous
T53	Detailed_description 1042 1055	grew slightly
R25	MODIFY Arg1:T53 Arg2:E26	
R26	MODIFY Arg1:T52 Arg2:E26	
T54	Sign_symptom 1108 1131	symptomatic improvement
E27	Sign_symptom:T54 
T55	Sign_symptom 1156 1189	improvement in general appearance
E28	Sign_symptom:T55 
T56	Sign_symptom 1194 1201	dyspnea
E29	Sign_symptom:T56 
A1	TREND E29 DEC
T57	Sign_symptom 1228 1232	pain
E30	Sign_symptom:T57 
A2	TREND E30 DEC
T58	Biological_structure 1223 1227	bone
R27	MODIFY Arg1:T58 Arg2:E30	
T59	Therapeutic_procedure 1265 1287	oxygen supplementation
E31	Therapeutic_procedure:T59 
A3	POLARITY E31 NEG
T60	Sign_symptom 1306 1313	lesions
E32	Sign_symptom:T60 
T61	Biological_structure 1293 1305	subcutaneous
R28	MODIFY Arg1:T61 Arg2:E32	
A4	TREND E32 DEC
T62	Sign_symptom 1415 1422	lesions
E33	Sign_symptom:T62 
T63	Biological_structure 1410 1414	bone
R29	MODIFY Arg1:T63 Arg2:E33	
A5	TREND E33 DEC
T64	Date 1363 1379	by the 12th week
E34	Date:T64 
T65	Lab_value 1343 1362	complete resolution
R30	MODIFY Arg1:T65 Arg2:E32	
R31	MODIFY Arg1:E34 Arg2:T65	
T66	Medication 1465 1474	nivolumab
E35	Medication:T66 
T67	Date 1475 1490	until June 2015
E36	Date:T67 
R32	BEFORE Arg1:E36 Arg2:E35	
T68	Sign_symptom 1576 1585	pneumonia
E37	Sign_symptom:T68 
T69	Detailed_description 1555 1575	bacterial aspiration
R33	MODIFY Arg1:T69 Arg2:E37	
T70	Outcome 1590 1601	passed away
E38	Outcome:T70 
T71	Date 1605 1614	June 2015
E39	Date:T71 
R34	BEFORE Arg1:E39 Arg2:E38	
R35	BEFORE Arg1:E1 Arg2:E2	
*	OVERLAP E2 E5
R36	BEFORE Arg1:E5 Arg2:E6	
*	OVERLAP E6 E7 E9
R37	BEFORE Arg1:E9 Arg2:E10	
*	OVERLAP E10 E11
R38	BEFORE Arg1:E11 Arg2:E13	
*	OVERLAP E13 E12 E14 E15 E16 E17
R39	BEFORE Arg1:E17 Arg2:E18	
R40	BEFORE Arg1:E18 Arg2:E19	
*	OVERLAP E19 E20
R41	BEFORE Arg1:E20 Arg2:E21	
*	OVERLAP E21 E22 E23 E24 E25 E26
R42	BEFORE Arg1:E26 Arg2:E27	
*	OVERLAP E27 E28 E29 E30 E31
R43	BEFORE Arg1:E31 Arg2:E32	
*	OVERLAP E32 E33
R44	BEFORE Arg1:E33 Arg2:E35	
R45	BEFORE Arg1:E35 Arg2:E37	
R46	BEFORE Arg1:E37 Arg2:E38