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T1 Age 4 15 21-year-old T2 History 501 567 The patient did not have a medical history or a current medication T3 Occupation 578 585 student T4 History 587 638 He did not smoke and did not use recreational drugs T5 History 640 674 He only drank alcohol occasionally T6 Family_history 676 772 There was no family history of thromboembolism, cardiovascular problems, or hematologic diseases T7 Clinical_event 24 33 presented E1 Clinical_event:T7 T8 Nonbiological_location 41 69 closest emergency department R1 MODIFY Arg1:T8 Arg2:E1 T9 Time 73 77 8 PM E2 Time:T9 T10 Sign_symptom 82 88 nausea E3 Sign_symptom:T10 T11 Sign_symptom 90 98 numbness E4 Sign_symptom:T11 T12 Biological_structure 106 116 left limbs R2 MODIFY Arg1:T12 Arg2:E4 T13 Sign_symptom 118 143 incoordination of walking E5 Sign_symptom:T13 T14 Sign_symptom 148 158 dysarthria E6 Sign_symptom:T14 T15 Time 216 230 4 hours before E7 Time:T15 T16 Sign_symptom 169 183 symptomatology E8 Sign_symptom:T16 #1 AnnotatorNotes E8 i.e., the symptoms started and increased T17 Detailed_description 199 210 progressive R3 MODIFY Arg1:T17 Arg2:E8 T18 Time 293 297 4 PM E9 Time:T18 T19 Sign_symptom 249 255 nausea E10 Sign_symptom:T19 T20 Sign_symptom 307 315 headache E11 Sign_symptom:T20 A1 POLARITY E11 NEG T21 Sign_symptom 324 328 pain E12 Sign_symptom:T21 A2 POLARITY E12 NEG T22 Biological_structure 317 323 nuchal R4 MODIFY Arg1:T22 Arg2:E12 T23 Sign_symptom 333 338 vomit E13 Sign_symptom:T23 A3 POLARITY E13 NEG T24 Time 350 363 after 5.30 PM E14 Time:T24 T25 Sign_symptom 369 377 numbness E15 Sign_symptom:T25 T26 Biological_structure 385 395 left limbs R5 MODIFY Arg1:T26 Arg2:E15 T27 Sign_symptom 404 429 incoordination of walking E16 Sign_symptom:T27 T28 Time 437 441 7 PM E17 Time:T28 T29 Sign_symptom 442 452 dysarthria E18 Sign_symptom:T29 T30 Diagnostic_procedure 787 796 evaluated E19 Diagnostic_procedure:T30 T31 Nonbiological_location 802 814 neurosurgeon T32 Nonbiological_location 822 836 emergency unit R6 MODIFY Arg1:T31 Arg2:E19 R7 MODIFY Arg1:T32 Arg2:E19 T33 Diagnostic_procedure 853 855 CT E20 Diagnostic_procedure:T33 T34 Biological_structure 847 852 brain R8 MODIFY Arg1:T34 Arg2:E20 T35 Sign_symptom 895 906 hypodensity E21 Sign_symptom:T35 T36 Detailed_description 878 894 infracentimetric R9 MODIFY Arg1:T36 Arg2:E21 T37 Biological_structure 914 930 thalamic nucleus R10 MODIFY Arg1:T37 Arg2:E21 T38 Detailed_description 939 948 left side R11 MODIFY Arg1:T38 Arg2:E21 T39 Biological_structure 960 1000 level of the right cerebellar hemisphere R12 MODIFY Arg1:T39 Arg2:E21 T40 Biological_structure 1008 1022 PICA territory R13 MODIFY Arg1:T40 Arg2:E21 T41 Diagnostic_procedure 1041 1046 X-ray E22 Diagnostic_procedure:T41 T42 Biological_structure 1035 1040 chest R14 MODIFY Arg1:T42 Arg2:E22 T43 Sign_symptom 1063 1086 widened projection area E23 Sign_symptom:T43 T44 Biological_structure 1094 1110 right side hilum R15 MODIFY Arg1:T44 Arg2:E23 T45 Sign_symptom 1124 1151 other pathological findings E24 Sign_symptom:T45 A4 POLARITY E24 NEG T46 Clinical_event 1187 1191 sent E25 Clinical_event:T46 T47 Nonbiological_location 1199 1259 National Institute of Neurology and Cerebrovascular Diseases R16 MODIFY Arg1:T47 Arg2:E25 T48 Clinical_event 1264 1276 consultation E26 Clinical_event:T48 T49 Therapeutic_procedure 1281 1298 special treatment E27 Therapeutic_procedure:T49 T50 Clinical_event 1321 1335 transportation E28 Clinical_event:T50 T51 Detailed_description 1311 1320 ambulance R17 MODIFY Arg1:T51 Arg2:E28 T52 Sign_symptom 1365 1373 vomiting E29 Sign_symptom:T52 T53 Detailed_description 1344 1352 repeated R18 MODIFY Arg1:T53 Arg2:E29 T54 Diagnostic_procedure 1387 1407 physical examination E30 Diagnostic_procedure:T54 T55 Time 1412 1418 10 P.M E31 Time:T55 T56 Diagnostic_procedure 1434 1445 vital signs E32 Diagnostic_procedure:T56 T57 Lab_value 1427 1433 normal R19 MODIFY Arg1:T57 Arg2:E32 T58 Diagnostic_procedure 1447 1461 blood pressure E33 Diagnostic_procedure:T58 T59 Lab_value 1462 1473 130/ 80mmHg R20 MODIFY Arg1:T59 Arg2:E33 T60 Diagnostic_procedure 1475 1485 heart rate E34 Diagnostic_procedure:T60 T61 Lab_value 1486 1506 100 beats per minute R21 MODIFY Arg1:T61 Arg2:E34 T62 Diagnostic_procedure 1518 1534 body temperature E35 Diagnostic_procedure:T62 T63 Lab_value 1511 1517 normal R22 MODIFY Arg1:T63 Arg2:E35 T64 Lab_value 1535 1541 36,8°C R23 MODIFY Arg1:T64 Arg2:E35 T65 Diagnostic_procedure 1547 1567 cardiopulmonary exam E36 Diagnostic_procedure:T65 T66 Lab_value 1572 1578 normal R24 MODIFY Arg1:T66 Arg2:E36 T67 Sign_symptom 1583 1597 carotid bruits E37 Sign_symptom:T67 A5 POLARITY E37 NEG T68 Diagnostic_procedure 1619 1643 neurological examination E38 Diagnostic_procedure:T68 T69 Lab_value 1660 1678 normal orientation R25 MODIFY Arg1:T69 Arg2:E38 T70 Diagnostic_procedure 1712 1718 pupils E39 Diagnostic_procedure:T70 T71 Lab_value 1703 1711 reactive T72 Lab_value 1696 1701 equal R26 MODIFY Arg1:T71 Arg2:E39 R27 MODIFY Arg1:T72 Arg2:E39 T73 Sign_symptom 1730 1740 strabismus E40 Sign_symptom:T73 T74 Biological_structure 1748 1756 left eye R28 MODIFY Arg1:T74 Arg2:E40 T75 Detailed_description 1720 1729 divergent R29 MODIFY Arg1:T75 Arg2:E40 T76 Sign_symptom 1769 1778 nystagmus E41 Sign_symptom:T76 T77 Detailed_description 1758 1768 horizontal R30 MODIFY Arg1:T77 Arg2:E41 T78 Diagnostic_procedure 1787 1798 deglutition E42 Diagnostic_procedure:T78 R31 SUB_PROCEDURE Arg1:E33 Arg2:E32 R32 SUB_PROCEDURE Arg1:E34 Arg2:E32 R33 SUB_PROCEDURE Arg1:E35 Arg2:E32 T79 Disease_disorder 1805 1812 paresis E43 Disease_disorder:T79 T80 Severity 1800 1804 mild R34 MODIFY Arg1:T80 Arg2:E43 T81 Lab_value 1780 1786 normal R35 MODIFY Arg1:T81 Arg2:E42 T82 Biological_structure 1820 1828 left arm R36 MODIFY Arg1:T82 Arg2:E43 T83 Disease_disorder 1830 1836 ataxia E44 Disease_disorder:T83 T84 Biological_structure 1840 1849 all limbs R37 MODIFY Arg1:T84 Arg2:E44 T85 Biological_structure 1859 1889 accent on the left extremities R38 MODIFY Arg1:T85 Arg2:E44 T86 Sign_symptom 1891 1899 numbness E45 Sign_symptom:T86 T87 Biological_structure 1907 1917 left limbs R39 MODIFY Arg1:T87 Arg2:E45 T88 Diagnostic_procedure 1966 1972 reflex E46 Diagnostic_procedure:T88 T89 Lab_value 1919 1937 bilateral response R40 MODIFY Arg1:T89 Arg2:E46 T90 Biological_structure 1949 1965 all deep tendons R41 MODIFY Arg1:T90 Arg2:E46 T91 Sign_symptom 1974 1987 Babinski sign E47 Sign_symptom:T91 T92 Detailed_description 1995 2004 left side R42 MODIFY Arg1:T92 Arg2:E47 T93 Diagnostic_procedure 2020 2028 language E48 Diagnostic_procedure:T93 T94 Lab_value 2006 2019 stereotypical R43 MODIFY Arg1:T94 Arg2:E48 T95 Detailed_description 2046 2096 able to repeat a few words and fragment of phrases R44 MODIFY Arg1:T95 Arg2:T94 T96 Detailed_description 2104 2148 perform simple commands of medium complexity R45 MODIFY Arg1:T96 Arg2:T94 T97 Diagnostic_procedure 2154 2173 laboratory analysis E49 Diagnostic_procedure:T97 T98 Diagnostic_procedure 2195 2208 hemoleucogram E50 Diagnostic_procedure:T98 T99 Lab_value 2188 2194 normal R46 MODIFY Arg1:T99 Arg2:E50 R47 SUB_PROCEDURE Arg1:E50 Arg2:E49 T100 Diagnostic_procedure 2217 2230 blood glucose E51 Diagnostic_procedure:T100 T101 Lab_value 2210 2216 normal R48 MODIFY Arg1:T101 Arg2:E51 T102 Lab_value 2237 2249 9,11 mmol/ L R49 MODIFY Arg1:T102 Arg2:E51 R50 SUB_PROCEDURE Arg1:E51 Arg2:E49 T103 Diagnostic_procedure 2281 2297 serum creatinine E52 Diagnostic_procedure:T103 T104 Lab_value 2298 2309 0,69mmol/ L R51 MODIFY Arg1:T104 Arg2:E52 R52 SUB_PROCEDURE Arg1:E52 Arg2:E49 T105 Diagnostic_procedure 2334 2357 total serum cholesterol E53 Diagnostic_procedure:T105 T106 Lab_value 2358 2368 5,2mmol/ L R53 MODIFY Arg1:T106 Arg2:E53 R54 SUB_PROCEDURE Arg1:E53 Arg2:E49 T107 Diagnostic_procedure 2413 2426 thrombophilia E54 Diagnostic_procedure:T107 T108 Lab_value 2432 2440 negative R55 MODIFY Arg1:T108 Arg2:E54 T109 Diagnostic_procedure 2469 2481 sinus rhythm E55 Diagnostic_procedure:T109 T110 Detailed_description 2489 2492 ECG R56 MODIFY Arg1:T110 Arg2:E55 T111 Lab_value 2462 2468 normal R57 MODIFY Arg1:T111 Arg2:E55 T112 Diagnostic_procedure 2504 2506 CT E56 Diagnostic_procedure:T112 T113 Biological_structure 2498 2503 brain R58 MODIFY Arg1:T113 Arg2:E56 T114 Sign_symptom 2594 2605 hypodensity E57 Sign_symptom:T114 T115 Detailed_description 2577 2593 infracentimetric R59 MODIFY Arg1:T115 Arg2:E57 T116 Biological_structure 2613 2647 level of the left thalamic nucleus R60 MODIFY Arg1:T116 Arg2:E57 T117 Biological_structure 2659 2699 level of the right cerebellar hemisphere T118 Biological_structure 2707 2721 PICA territory R61 MODIFY Arg1:T117 Arg2:E57 R62 MODIFY Arg1:T118 Arg2:E57 T119 Diagnostic_procedure 2731 2741 ultrasound E58 Diagnostic_procedure:T119 T120 Detailed_description 2723 2730 Doppler R63 MODIFY Arg1:T120 Arg2:E58 T121 Biological_structure 2746 2781 cerebral and cervical blood vessels R64 MODIFY Arg1:T121 Arg2:E58 T122 Diagnostic_procedure 2818 2833 flow velocities E59 Diagnostic_procedure:T122 T123 Lab_value 2805 2810 frena R65 MODIFY Arg1:T123 Arg2:E59 T124 Biological_structure 2841 2881 V2 segment of the right vertebral artery R66 MODIFY Arg1:T124 Arg2:E59 T125 Diagnostic_procedure 2968 2972 flow E60 Diagnostic_procedure:T125 T126 Lab_value 2938 2960 complete disappearance R67 MODIFY Arg1:T126 Arg2:E60 T127 Biological_structure 2980 2990 V3 segment R68 MODIFY Arg1:T127 Arg2:E60 T128 Sign_symptom 3021 3028 lesions E61 Sign_symptom:T128 A6 POLARITY E61 NEG T129 Sign_symptom 2886 2904 accentuated aspect E62 Sign_symptom:T129 T130 Biological_structure 2912 2928 high V2 segments R69 MODIFY Arg1:T130 Arg2:E62 T131 Detailed_description 3008 3020 atheromatous R70 MODIFY Arg1:T131 Arg2:E61 T132 Biological_structure 3000 3007 carotid R71 MODIFY Arg1:T132 Arg2:E61 T133 Sign_symptom 3032 3089 modifications of the trajectories or the arterial caliber E63 Sign_symptom:T133 A7 POLARITY E63 NEG T134 Disease_disorder 3129 3139 dissection E64 Disease_disorder:T134 A8 POLARITY E64 UNCERTAIN T135 Biological_structure 3147 3169 right vertebral artery R72 MODIFY Arg1:T135 Arg2:E64 T136 Detailed_description 3177 3192 higher segments R73 MODIFY Arg1:T136 Arg2:T135 T137 Diagnostic_procedure 3231 3234 MRI E65 Diagnostic_procedure:T137 T138 Biological_structure 3225 3230 angio T139 Biological_structure 3212 3220 cerebral R74 MODIFY Arg1:T138 Arg2:E65 R75 MODIFY Arg1:T139 Arg2:E65 T140 Coreference 3255 3258 MRI E66 Coreference:T140 R76 IDENTICAL Arg1:E66 Arg2:E65 T141 Diagnostic_procedure 3282 3287 FLAIR E67 Diagnostic_procedure:T141 T142 Lab_value 3288 3299 hypersignal R77 MODIFY Arg1:T142 Arg2:E67 T143 Detailed_description 3278 3280 T2 R78 MODIFY Arg1:T143 Arg2:E67 T144 Sign_symptom 3319 3343 restriction of diffusion E68 Sign_symptom:T144 T145 Diagnostic_procedure 3352 3355 ADC E69 Diagnostic_procedure:T145 #2 AnnotatorNotes E69 apparent diffusion coefficient T146 Lab_value 3348 3351 low R79 MODIFY Arg1:T146 Arg2:E69 T147 Biological_structure 3373 3428 right cerebellar area of the postero-inferior territory R80 MODIFY Arg1:T147 Arg2:T142 T148 Biological_structure 3430 3469 anterior bilateral cerebellar territory R81 MODIFY Arg1:T148 Arg2:T142 T149 Biological_structure 3471 3495 left cerebellar peduncle R82 MODIFY Arg1:T149 Arg2:T142 T150 Biological_structure 3497 3530 both right > left thalamic nuclei R83 MODIFY Arg1:T150 Arg2:T142 T151 Biological_structure 3543 3574 subcortical occipital bilateral R84 MODIFY Arg1:T151 Arg2:T142 T152 Sign_symptom 3584 3599 ischemic aspect E70 Sign_symptom:T152 T153 Biological_structure 3630 3662 in the vertebrobasilar territory R85 MODIFY Arg1:T153 Arg2:E70 T154 Diagnostic_procedure 3664 3669 T1 FS E71 Diagnostic_procedure:T154 R86 SUB_PROCEDURE Arg1:E67 Arg2:E66 R87 SUB_PROCEDURE Arg1:E71 Arg2:E66 T155 Lab_value 3670 3681 hypersignal R88 MODIFY Arg1:T155 Arg2:E71 T156 Biological_structure 3701 3758 entire intracranial segment of the right vertebral artery T157 Biological_structure 3767 3789 cranio-spinal junction R89 MODIFY Arg1:T156 Arg2:T155 R90 MODIFY Arg1:T157 Arg2:T155 T158 Diagnostic_procedure 3798 3810 angiographic E72 Diagnostic_procedure:T158 T159 Detailed_description 3811 3819 arterial R91 MODIFY Arg1:T159 Arg2:E72 T160 Detailed_description 3820 3822 3D T161 Detailed_description 3823 3826 TOF #3 AnnotatorNotes T161 time-of-flight R92 MODIFY Arg1:T160 Arg2:E72 R93 MODIFY Arg1:T161 Arg2:E72 T162 Diagnostic_procedure 3863 3867 flow E73 Diagnostic_procedure:T162 T163 Lab_value 3857 3862 rapid R94 MODIFY Arg1:T163 Arg2:E73 T164 Biological_structure 3875 3897 right vertebral artery R95 MODIFY Arg1:T164 Arg2:E73 T165 Biological_structure 3915 3935 up to the C2 segment R96 MODIFY Arg1:T165 Arg2:E73 T166 Sign_symptom 3967 3976 pinch out E74 Sign_symptom:T166 T167 Detailed_description 3955 3966 progressive R97 MODIFY Arg1:T167 Arg2:E74 T168 Shape 3995 4011 flute beak shape R98 MODIFY Arg1:T168 Arg2:E74 T169 Diagnostic_procedure 4063 4073 rapid flow E75 Diagnostic_procedure:T169 T170 Lab_value 4048 4055 absence R99 MODIFY Arg1:T170 Arg2:E75 T171 Biological_structure 4013 4033 Distal of this level R100 MODIFY Arg1:T171 Arg2:E75 T172 Biological_structure 4100 4110 right PICA #4 AnnotatorNotes T172 posterior inferior cerebellar artery T173 Diagnostic_procedure 4111 4124 visualization E76 Diagnostic_procedure:T173 T174 Lab_value 4092 4096 lack R101 MODIFY Arg1:T174 Arg2:E76 R102 MODIFY Arg1:T172 Arg2:E76 T175 Diagnostic_procedure 4130 4133 MRI E77 Diagnostic_procedure:T175 T176 Disease_disorder 4162 4172 dissection E78 Disease_disorder:T176 T177 Detailed_description 4153 4161 subacute R103 MODIFY Arg1:T177 Arg2:E78 T178 Biological_structure 4180 4202 right vertebral artery R104 MODIFY Arg1:T178 Arg2:E78 T179 Diagnostic_procedure 4247 4257 dimensions E79 Diagnostic_procedure:T179 T180 Diagnostic_procedure 4259 4264 shape E80 Diagnostic_procedure:T180 T181 Diagnostic_procedure 4270 4280 topography E81 Diagnostic_procedure:T181 T182 Biological_structure 4208 4235 cerebral ventricular system R105 MODIFY Arg1:T182 Arg2:E79 R106 MODIFY Arg1:T182 Arg2:E80 R107 MODIFY Arg1:T182 Arg2:E81 T183 Lab_value 4240 4246 normal R108 MODIFY Arg1:T183 Arg2:E79 R109 MODIFY Arg1:T183 Arg2:E80 R110 MODIFY Arg1:T183 Arg2:E81 T184 Medication 4510 4517 Heparin E82 Medication:T184 T185 Diagnostic_procedure 4622 4632 APTT value E83 Diagnostic_procedure:T185 #5 AnnotatorNotes E83 activated partial thromboplastin time T186 Lab_value 4649 4671 range of 50-70 seconds R111 MODIFY Arg1:T186 Arg2:E83 T187 Sign_symptom 4386 4393 lesions E84 Sign_symptom:T187 T188 Detailed_description 4377 4385 ischemic R112 MODIFY Arg1:T188 Arg2:E84 T189 Biological_structure 4422 4447 vertebrobasilar territory R113 MODIFY Arg1:T189 Arg2:E84 T190 Disease_disorder 4468 4478 dissection E85 Disease_disorder:T190 T191 Detailed_description 4459 4467 subacute R114 MODIFY Arg1:T191 Arg2:E85 T192 Biological_structure 4486 4508 right vertebral artery R115 MODIFY Arg1:T192 Arg2:E85 T193 Diagnostic_procedure 4286 4311 pericerebral fluid spaces E86 Diagnostic_procedure:T193 T194 Diagnostic_procedure 4320 4334 basal cisterns E87 Diagnostic_procedure:T194 T195 Lab_value 4340 4346 normal R116 MODIFY Arg1:T195 Arg2:E87 R117 MODIFY Arg1:T195 Arg2:E86 #6 AnnotatorNotes E86 labeled as a diagnostic because of the "normal" result T196 Therapeutic_procedure 4683 4703 prophylactic therapy E88 Therapeutic_procedure:T196 T197 Detailed_description 4708 4720 stress ulcer R118 MODIFY Arg1:T197 Arg2:E88 T198 Date 4736 4748 After 7 days E89 Date:T198 T199 Medication 4797 4809 acenocumarol E90 Medication:T199 T200 Diagnostic_procedure 4931 4934 INR E91 Diagnostic_procedure:T200 #7 AnnotatorNotes E91 International Normalized Ratio T201 Lab_value 4935 4946 therapeutic R119 MODIFY Arg1:T201 Arg2:E91 T202 Detailed_description 4954 4967 2-3 intervals R120 MODIFY Arg1:T202 Arg2:E91 T203 Medication 4860 4872 acenocumarol E92 Medication:T203 T204 Medication 4897 4904 heparin E93 Medication:T204 T205 Diagnostic_procedure 4973 4982 evolution E94 Diagnostic_procedure:T205 T206 Lab_value 4987 4996 favorable R121 MODIFY Arg1:T206 Arg2:E94 T207 Diagnostic_procedure 5024 5038 verbal fluency E95 Diagnostic_procedure:T207 T208 Lab_value 5010 5019 regaining R122 MODIFY Arg1:T208 Arg2:E95 T209 Sign_symptom 5060 5080 autonomy in movement E96 Sign_symptom:T209 T210 Disease_disorder 5086 5092 ataxia E97 Disease_disorder:T210 A9 TREND E97 DEC T211 Detailed_description 5097 5124 remitted at the right limbs R123 MODIFY Arg1:T211 Arg2:E97 T212 Detailed_description 5129 5162 persisted at the left extremities R124 MODIFY Arg1:T212 Arg2:E97 T213 Clinical_event 5217 5227 discharged E98 Clinical_event:T213 T214 Nonbiological_location 5228 5232 home R125 MODIFY Arg1:T214 Arg2:E98 T215 Other_entity 5242 5380 recommendation to continue the treatment with Acenocumarol for 6 months with clinical, paraclinical and treatment reevaluation at 6 months #8 AnnotatorNotes T215 Unlabeled as per next sentence - patient did not complete follow up T216 Clinical_event 5386 5395 follow up E99 Clinical_event:T216 A10 POLARITY E99 NEG T217 Date 5464 5478 after 6 months E100 Date:T217 T218 Clinical_event 5441 5447 return E101 Clinical_event:T218 A11 POLARITY E101 NEG T219 Nonbiological_location 5455 5463 hospital R126 MODIFY Arg1:T219 Arg2:E101 * OVERLAP E1 E2 E3 E4 E5 E6 R127 AFTER Arg1:E6 Arg2:E8 * OVERLAP E8 E7 E10 E9 E11 E12 E13 R128 BEFORE Arg1:E13 Arg2:E14 * OVERLAP E14 E15 E16 R129 BEFORE Arg1:E16 Arg2:E17 * OVERLAP E17 E18 R130 BEFORE Arg1:E18 Arg2:E19 * OVERLAP E19 E20 E21 E22 E23 E24 R131 BEFORE Arg1:E24 Arg2:E25 * OVERLAP E25 E26 E27 E28 E29 R132 BEFORE Arg1:E29 Arg2:E30 * OVERLAP E30 E31 E32 E36 E37 E38 E39 E40 E41 E42 E43 E44 E45 E46 E47 E48 E49 E54 E55 R133 AFTER Arg1:E55 Arg2:E56 * OVERLAP E56 E57 R134 BEFORE Arg1:E57 Arg2:E58 * OVERLAP E58 E59 E62 E60 E61 E63 E64 E65 E66 E68 E70 E72 E73 E74 E75 E76 E77 E78 E79 E80 E81 E86 E87 A12 POLARITY E78 MAYBE_POS R135 BEFORE Arg1:E87 Arg2:E84 * OVERLAP E84 E85 R136 BEFORE Arg1:E85 Arg2:E82 * OVERLAP E82 E83 E88 R137 BEFORE Arg1:E88 Arg2:E89 * OVERLAP E89 E90 E92 E93 R138 BEFORE Arg1:E93 Arg2:E91 R139 BEFORE Arg1:E91 Arg2:E94 * OVERLAP E94 E95 E96 E97 T220 Lab_value 5188 5199 improvement R140 MODIFY Arg1:T220 Arg2:E97 R141 BEFORE Arg1:E97 Arg2:E98 R142 BEFORE Arg1:E98 Arg2:E99 * OVERLAP E99 E101 E100