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T1 Age 2 13 13 year-old T2 Sex 14 17 boy T3 Clinical_event 18 27 presented E1 Clinical_event:T3 T4 History 113 168 no significant past medical, surgical or family history T5 Duration 35 42 1 month E2 Duration:T5 T6 Sign_symptom 92 101 epistaxis E3 Sign_symptom:T6 T7 Detailed_description 79 91 small volume T8 Biological_structure 54 66 intermittent R1 MODIFY Arg1:T7 Arg2:E3 R2 MODIFY Arg1:T8 Arg2:E3 T9 Diagnostic_procedure 170 190 Physical examination E4 Diagnostic_procedure:T9 T10 Sign_symptom 222 226 mass E5 Sign_symptom:T10 T11 Detailed_description 215 221 fleshy T12 Biological_structure 202 214 left palatal T13 Biological_structure 239 260 left posterior molars R3 MODIFY Arg1:T12 Arg2:E5 R4 MODIFY Arg1:T13 Arg2:E5 T14 Diagnostic_procedure 264 290 nasoendoscopic examination E6 Diagnostic_procedure:T14 T15 Sign_symptom 312 320 swelling E7 Sign_symptom:T15 T16 Severity 306 311 large R5 MODIFY Arg1:T16 Arg2:E7 T17 Biological_structure 328 362 floor of left anterior nasal space R6 MODIFY Arg1:T17 Arg2:E7 T18 Biological_structure 378 398 left inferior meatus T19 Biological_structure 416 434 inferior turbinate R7 MODIFY Arg1:T18 Arg2:E7 R8 MODIFY Arg1:T19 Arg2:E7 T20 Diagnostic_procedure 436 455 Computed Tomography E8 Diagnostic_procedure:T20 T21 Diagnostic_procedure 457 459 CT E9 Diagnostic_procedure:T21 T22 Biological_structure 468 485 paranasal sinuses R9 MODIFY Arg1:T22 Arg2:E8 R10 IDENTICAL Arg1:E9 Arg2:E8 T23 Sign_symptom 522 528 lesion E10 Sign_symptom:T23 T24 Detailed_description 516 521 lytic T25 Detailed_description 506 515 expansile T26 Detailed_description 495 504 lobulated R11 MODIFY Arg1:T24 Arg2:E10 R12 MODIFY Arg1:T25 Arg2:E10 R13 MODIFY Arg1:T26 Arg2:E10 T27 Biological_structure 532 544 left maxilla R14 MODIFY Arg1:T27 Arg2:E10 T28 Detailed_description 560 573 lucent center T29 Detailed_description 578 603 peripheral calcifications R15 MODIFY Arg1:T28 Arg2:E10 R16 MODIFY Arg1:T29 Arg2:E10 T30 Coreference 609 615 lesion E11 Coreference:T30 R17 IDENTICAL Arg1:E11 Arg2:E10 T31 Detailed_description 638 665 large soft tissue component T32 Sign_symptom 703 723 contrast enhancement E12 Sign_symptom:T32 T33 Severity 684 688 mild T34 Detailed_description 689 702 heterogeneous R18 MODIFY Arg1:T34 Arg2:E12 R19 MODIFY Arg1:T33 Arg2:E12 R20 MODIFY Arg1:T31 Arg2:E11 T35 Coreference 729 735 lesion E13 Coreference:T35 R21 IDENTICAL Arg1:E13 Arg2:E11 T36 Biological_structure 756 779 left maxillary alveolus T37 Biological_structure 795 811 left hard palate R22 MODIFY Arg1:T36 Arg2:E13 R23 MODIFY Arg1:T37 Arg2:E13 T38 Biological_structure 813 862 inferior part of the anterior left maxillary wall T39 Biological_structure 867 893 medial left maxillary wall R24 MODIFY Arg1:T38 Arg2:E13 R25 MODIFY Arg1:T39 Arg2:E13 T40 Coreference 899 905 lesion E14 Coreference:T40 R26 IDENTICAL Arg1:E14 Arg2:E13 T41 Biological_structure 924 973 roots of the left maxillary molars and pre-molars R27 MODIFY Arg1:T41 Arg2:E14 T42 Biological_structure 995 1013 left orbital floor R28 MODIFY Arg1:T42 Arg2:E14 T43 Sign_symptom 1037 1045 invasion E15 Sign_symptom:T43 A1 POLARITY E15 NEG T44 Biological_structure 1029 1036 orbital R29 MODIFY Arg1:T44 Arg2:E15 T45 Diagnostic_procedure 1082 1101 18-FDG PET-CT study E16 Diagnostic_procedure:T45 T46 Disease_disorder 1210 1228 metastatic disease E17 Disease_disorder:T46 A2 POLARITY E17 NEG T47 Detailed_description 1201 1209 FDG-avid R30 MODIFY Arg1:T47 Arg2:E17 T48 Coreference 1107 1111 mass E18 Coreference:T48 R31 IDENTICAL Arg1:E18 Arg2:E14 T50 Lab_value 1162 1178 index SUVmax 9.7 T49 Detailed_description 1141 1155 hypermetabolic T51 Biological_structure 1124 1136 left maxilla R32 MODIFY Arg1:T51 Arg2:E18 R33 MODIFY Arg1:T49 Arg2:E18 R34 MODIFY Arg1:T50 Arg2:E18 T52 Diagnostic_procedure 1243 1260 incisional biopsy E19 Diagnostic_procedure:T52 T53 Detailed_description 1232 1242 trans-oral R35 MODIFY Arg1:T53 Arg2:E19 T54 Sign_symptom 1281 1285 mass E20 Sign_symptom:T54 T55 Biological_structure 1268 1280 left palatal R36 MODIFY Arg1:T55 Arg2:E20 T56 Disease_disorder 1349 1375 mesenchymal chondrosarcoma E21 Disease_disorder:T56 T57 Detailed_description 1395 1411 biphasic pattern R37 MODIFY Arg1:T57 Arg2:E21 T58 Detailed_description 1422 1449 sheets of small round cells R38 MODIFY Arg1:T58 Arg2:E21 T59 Detailed_description 1455 1495 hemangiopericytoma-like vascular pattern T60 Detailed_description 1500 1528 mature cartilaginous islands R39 MODIFY Arg1:T59 Arg2:E21 R40 MODIFY Arg1:T60 Arg2:E21 T61 Therapeutic_procedure 1566 1578 maxillectomy E22 Therapeutic_procedure:T61 T62 Therapeutic_procedure 1591 1600 rhinotomy E23 Therapeutic_procedure:T62 R41 SUB_PROCEDURE Arg1:E23 Arg2:E22 T63 Detailed_description 1583 1590 lateral R42 MODIFY Arg1:T63 Arg2:E23 T64 Detailed_description 1552 1565 left subtotal R43 MODIFY Arg1:T64 Arg2:E22 T65 Detailed_description 1605 1625 translabial approach R44 MODIFY Arg1:T65 Arg2:E22 T66 Diagnostic_procedure 1637 1646 histology E24 Diagnostic_procedure:T66 A3 POLARITY E21 MAYBE_POS T67 Disease_disorder 1692 1718 mesenchymal chondrosarcoma E25 Disease_disorder:T67 T68 Distance 1667 1670 5cm R45 MODIFY Arg1:T68 Arg2:E25 T69 Lab_value 1671 1681 high-grade T70 Lab_value 1683 1690 Grade 3 R46 MODIFY Arg1:T70 Arg2:E25 R47 MODIFY Arg1:T69 Arg2:E25 T71 Sign_symptom 1766 1783 tumor involvement E26 Sign_symptom:T71 T72 Biological_structure 1731 1748 resection margins R48 MODIFY Arg1:T72 Arg2:E26 T73 Medication 1825 1837 chemotherapy E27 Medication:T73 T74 Detailed_description 1816 1824 adjuvant R49 MODIFY Arg1:T74 Arg2:E27 R50 AFTER Arg1:E1 Arg2:E2 * OVERLAP E2 E3 R51 BEFORE Arg1:E3 Arg2:E4 * OVERLAP E4 E5 E6 E7 E8 E10 E11 E12 E13 E14 E15 R52 BEFORE Arg1:E15 Arg2:E16 * OVERLAP E16 E18 E17 R53 BEFORE Arg1:E17 Arg2:E19 * OVERLAP E19 E20 E21 R54 BEFORE Arg1:E21 Arg2:E22 R55 BEFORE Arg1:E22 Arg2:E24 * OVERLAP E24 E25 E26 R56 BEFORE Arg1:E26 Arg2:E27