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T1 Age 2 13 36-year-old T2 Sex 14 20 female T3 Nonbiological_location 38 58 emergency department T4 Clinical_event 21 30 presented E1 Clinical_event:T4 R1 MODIFY Arg1:T3 Arg2:E1 T5 Sign_symptom 98 102 pain E2 Sign_symptom:T5 T6 Biological_structure 76 97 right upper abdominal T7 Detailed_description 64 75 aggravating R2 MODIFY Arg1:T6 Arg2:E2 R3 MODIFY Arg1:T7 Arg2:E2 T8 Duration 107 114 2 hours E3 Duration:T8 T9 History 142 191 hepatitis B virus (HBV) carrier for several years T10 History 196 209 non-alcoholic T11 History 212 277 No other specific personal and familial medical history was noted T12 Diagnostic_procedure 287 301 blood pressure E4 Diagnostic_procedure:T12 T13 Lab_value 306 317 100/60 mmHg T14 Diagnostic_procedure 319 329 pulse rate E5 Diagnostic_procedure:T14 T15 Lab_value 330 336 70/min T16 Diagnostic_procedure 338 354 respiration rate E6 Diagnostic_procedure:T16 T17 Lab_value 355 361 20/min T18 Diagnostic_procedure 363 379 body temperature E7 Diagnostic_procedure:T18 R4 MODIFY Arg1:T13 Arg2:E4 R5 MODIFY Arg1:T15 Arg2:E5 R6 MODIFY Arg1:T17 Arg2:E6 T19 Lab_value 380 385 37.5℃ R7 MODIFY Arg1:T19 Arg2:E7 T20 Diagnostic_procedure 391 410 laboratory findings E8 Diagnostic_procedure:T20 T21 Diagnostic_procedure 416 432 white blood cell E9 Diagnostic_procedure:T21 T22 Lab_value 433 443 12,000/mm3 R8 MODIFY Arg1:T22 Arg2:E9 R9 SUB_PROCEDURE Arg1:E9 Arg2:E8 T23 Diagnostic_procedure 445 449 poly E10 Diagnostic_procedure:T23 T24 Lab_value 451 454 70% R10 MODIFY Arg1:T24 Arg2:E10 R11 SUB_PROCEDURE Arg1:E10 Arg2:E9 T25 Diagnostic_procedure 457 467 hemoglobin E11 Diagnostic_procedure:T25 T26 Lab_value 468 477 12.8 g/dL R12 MODIFY Arg1:T26 Arg2:E11 T27 Diagnostic_procedure 479 487 platelet E12 Diagnostic_procedure:T27 T28 Lab_value 488 499 198,000/mm3 R13 MODIFY Arg1:T28 Arg2:E12 T29 Diagnostic_procedure 501 517 prothrombin time E13 Diagnostic_procedure:T29 T30 Lab_value 518 530 14.3 seconds R14 MODIFY Arg1:T30 Arg2:E13 T31 Diagnostic_procedure 532 562 international normalized ratio E14 Diagnostic_procedure:T31 T32 Lab_value 563 567 1.11 R15 MODIFY Arg1:T32 Arg2:E14 T33 Diagnostic_procedure 569 595 aspartate aminotransferase E15 Diagnostic_procedure:T33 T34 Lab_value 596 603 22 IU/L R16 MODIFY Arg1:T34 Arg2:E15 T35 Diagnostic_procedure 605 629 alanine aminotransferase E16 Diagnostic_procedure:T35 T36 Lab_value 630 637 12 IU/L R17 MODIFY Arg1:T36 Arg2:E16 T37 Diagnostic_procedure 639 654 total bilirubin E17 Diagnostic_procedure:T37 T38 Lab_value 655 664 0.5 mg/dL R18 MODIFY Arg1:T38 Arg2:E17 T39 Diagnostic_procedure 666 686 alkaline phosphatase E18 Diagnostic_procedure:T39 T40 Lab_value 687 695 134 IU/L R19 MODIFY Arg1:T40 Arg2:E18 T41 Diagnostic_procedure 697 718 lactate dehydrogenase E19 Diagnostic_procedure:T41 T42 Lab_value 719 727 295 IU/L R20 MODIFY Arg1:T42 Arg2:E19 T43 Diagnostic_procedure 729 758 gamma-glutamyl transpeptidase E20 Diagnostic_procedure:T43 T44 Lab_value 759 766 26 IU/L R21 MODIFY Arg1:T44 Arg2:E20 T45 Diagnostic_procedure 768 783 protein/albumin E21 Diagnostic_procedure:T45 T46 Lab_value 784 796 6.4/4.0 g/dL R22 MODIFY Arg1:T46 Arg2:E21 T47 Diagnostic_procedure 798 807 uric acid E22 Diagnostic_procedure:T47 T48 Lab_value 808 817 5.0 mg/dL R23 MODIFY Arg1:T48 Arg2:E22 T49 Diagnostic_procedure 819 849 blood urea nitrogen/creatinine E23 Diagnostic_procedure:T49 T50 Lab_value 850 864 16.6/0.7 mg/dL R24 MODIFY Arg1:T50 Arg2:E23 R25 SUB_PROCEDURE Arg1:E11 Arg2:E8 R26 SUB_PROCEDURE Arg1:E12 Arg2:E8 R27 SUB_PROCEDURE Arg1:E13 Arg2:E8 R28 SUB_PROCEDURE Arg1:E14 Arg2:E8 R29 SUB_PROCEDURE Arg1:E15 Arg2:E8 R30 SUB_PROCEDURE Arg1:E16 Arg2:E8 R31 SUB_PROCEDURE Arg1:E17 Arg2:E8 R32 SUB_PROCEDURE Arg1:E18 Arg2:E8 R33 SUB_PROCEDURE Arg1:E19 Arg2:E8 R34 SUB_PROCEDURE Arg1:E20 Arg2:E8 R35 SUB_PROCEDURE Arg1:E21 Arg2:E8 R36 SUB_PROCEDURE Arg1:E22 Arg2:E8 R37 SUB_PROCEDURE Arg1:E23 Arg2:E8 T51 Diagnostic_procedure 870 889 serum viral markers E24 Diagnostic_procedure:T51 T52 Diagnostic_procedure 895 900 HBsAg E25 Diagnostic_procedure:T52 T53 Diagnostic_procedure 906 914 anti-HBs E26 Diagnostic_procedure:T53 T54 Diagnostic_procedure 920 928 anti-HBc E27 Diagnostic_procedure:T54 T55 Diagnostic_procedure 934 939 HBeAg E28 Diagnostic_procedure:T55 T56 Diagnostic_procedure 945 953 anti-HBe E29 Diagnostic_procedure:T56 T57 Diagnostic_procedure 959 966 HBV-DNA E30 Diagnostic_procedure:T57 T58 Diagnostic_procedure 978 986 anti-HCV E31 Diagnostic_procedure:T58 T59 Diagnostic_procedure 995 1003 anti-HIV E32 Diagnostic_procedure:T59 T60 Lab_value 1005 1006 - T61 Lab_value 988 989 - T62 Lab_value 967 976 <20 IU/mL T63 Lab_value 955 956 + T64 Lab_value 941 942 - T65 Lab_value 930 931 + T66 Lab_value 916 917 - T67 Lab_value 902 903 + R38 MODIFY Arg1:T67 Arg2:E25 R39 MODIFY Arg1:T66 Arg2:E26 R40 MODIFY Arg1:T65 Arg2:E27 R41 MODIFY Arg1:T64 Arg2:E28 R42 MODIFY Arg1:T63 Arg2:E29 R43 MODIFY Arg1:T62 Arg2:E30 R44 MODIFY Arg1:T61 Arg2:E31 R45 MODIFY Arg1:T60 Arg2:E32 R46 SUB_PROCEDURE Arg1:E25 Arg2:E24 R47 SUB_PROCEDURE Arg1:E26 Arg2:E24 R48 SUB_PROCEDURE Arg1:E27 Arg2:E24 R49 SUB_PROCEDURE Arg1:E28 Arg2:E24 R50 SUB_PROCEDURE Arg1:E29 Arg2:E24 R51 SUB_PROCEDURE Arg1:E30 Arg2:E24 R52 SUB_PROCEDURE Arg1:E31 Arg2:E24 R53 SUB_PROCEDURE Arg1:E32 Arg2:E24 T68 Diagnostic_procedure 1023 1042 serum α-fetoprotein E33 Diagnostic_procedure:T68 T69 Diagnostic_procedure 1044 1047 AFP E34 Diagnostic_procedure:T69 R54 IDENTICAL Arg1:E34 Arg2:E33 T70 Lab_value 1053 1064 676.5 ng/mL R55 MODIFY Arg1:T70 Arg2:E33 T71 Diagnostic_procedure 1069 1094 carbohydrate antigen 19-9 E35 Diagnostic_procedure:T71 T72 Diagnostic_procedure 1096 1102 CA19-9 E36 Diagnostic_procedure:T72 R56 IDENTICAL Arg1:E36 Arg2:E35 T73 Lab_value 1104 1113 <0.6 U/mL R57 MODIFY Arg1:T73 Arg2:E35 T74 Diagnostic_procedure 1137 1139 CT E37 Diagnostic_procedure:T74 T75 Biological_structure 1127 1136 abdominal R58 MODIFY Arg1:T75 Arg2:E37 T76 Sign_symptom 1181 1185 mass E38 Sign_symptom:T76 T77 Detailed_description 1172 1180 necrotic T78 Distance 1161 1165 9 cm R59 MODIFY Arg1:T77 Arg2:E38 R60 MODIFY Arg1:T78 Arg2:E38 T81 Biological_structure 1218 1236 right hepatic lobe T79 Detailed_description 1186 1210 with internal hemorrhage R61 MODIFY Arg1:T79 Arg2:E38 R62 MODIFY Arg1:T81 Arg2:E38 T80 Biological_structure 1241 1263 ruptured to peritoneum R63 MODIFY Arg1:T80 Arg2:E38 T82 Therapeutic_procedure 1306 1321 bisectionectomy E39 Therapeutic_procedure:T82 T83 Biological_structure 1290 1305 hepatic central R64 MODIFY Arg1:T83 Arg2:E39 T84 Detailed_description 1280 1289 emergency R65 MODIFY Arg1:T84 Arg2:E39 T85 Disease_disorder 1380 1387 cHCC-CC E40 Disease_disorder:T85 #1 AnnotatorNotes E40 Combined hepatocellular-cholangiocarcinoma T86 Detailed_description 1393 1446 spindle cell metaplasia of cholangiocarcinoma element R66 MODIFY Arg1:T86 Arg2:E40 T87 Diagnostic_procedure 1461 1470 serum AFP E41 Diagnostic_procedure:T87 T88 Lab_value 1475 1484 decreased R67 MODIFY Arg1:T88 Arg2:E41 T89 Lab_value 1488 1498 7.67 ng/mL R68 MODIFY Arg1:T89 Arg2:E41 T90 Clinical_event 1510 1519 discharge E42 Clinical_event:T90 T91 Disease_disorder 1534 1541 cHCC-CC E43 Disease_disorder:T91 T92 Medication 1566 1578 chemotherapy E44 Medication:T92 T93 Detailed_description 1557 1565 adjuvant R69 MODIFY Arg1:T93 Arg2:E44 T94 Medication 1584 1598 tegafur/uracil E45 Medication:T94 T95 Medication 1600 1603 UFT E46 Medication:T95 R70 IDENTICAL Arg1:E46 Arg2:E45 T96 Duration 1627 1635 3 months E47 Duration:T96 T97 Date 1637 1651 3 months later E48 Date:T97 T98 Clinical_event 1653 1662 follow-up E49 Clinical_event:T98 T99 Diagnostic_procedure 1673 1675 CT E50 Diagnostic_procedure:T99 T100 Biological_structure 1663 1672 abdominal R71 MODIFY Arg1:T100 Arg2:E50 T101 Distance 1712 1718 5.5 cm T102 Sign_symptom 1741 1745 mass E51 Sign_symptom:T102 T103 Biological_structure 1725 1740 left subphrenic R72 MODIFY Arg1:T103 Arg2:E51 R73 MODIFY Arg1:T101 Arg2:E51 T104 Sign_symptom 1756 1767 enhancement E52 Sign_symptom:T104 T105 Severity 1751 1755 mild R74 MODIFY Arg1:T105 Arg2:E52 T106 Detailed_description 1771 1784 delayed image R75 MODIFY Arg1:T106 Arg2:E52 T107 Diagnostic_procedure 1801 1804 AFP E53 Diagnostic_procedure:T107 T108 Lab_value 1809 1818 increased T109 Lab_value 1822 1834 312.06 ng/mL R76 MODIFY Arg1:T108 Arg2:E53 R77 MODIFY Arg1:T109 Arg2:E53 T110 Therapeutic_procedure 1863 1874 splenectomy E54 Therapeutic_procedure:T110 T111 Detailed_description 1850 1862 laparoscopic R78 MODIFY Arg1:T111 Arg2:E54 T112 Therapeutic_procedure 1880 1893 mass excision E55 Therapeutic_procedure:T112 R79 SUB_PROCEDURE Arg1:E55 Arg2:E54 T113 Diagnostic_procedure 1898 1920 histologic examination E56 Diagnostic_procedure:T113 T114 Outcome 5025 5030 death E57 Outcome:T114 T115 Lab_value 1958 2027 proliferation of primitive-appearing mesenchymal spindle-shaped cells #2 AnnotatorNotes T115 about as good as I'm going to get with this one R80 MODIFY Arg1:T115 Arg2:E59 T116 Detailed_description 2029 2105 intimately admixed with the epithelial elements in a highly cellular pattern R81 MODIFY Arg1:T116 Arg2:T115 T117 Diagnostic_procedure 2176 2183 nucleus E58 Diagnostic_procedure:T117 T118 Diagnostic_procedure 1922 1942 mesenchymal elements E59 Diagnostic_procedure:T118 R82 SUB_PROCEDURE Arg1:E59 Arg2:E56 T119 Diagnostic_procedure 2107 2116 Cytoplasm E60 Diagnostic_procedure:T119 T120 Lab_value 2121 2166 more abundant than that of mature fibroblasts R83 SUB_PROCEDURE Arg1:E60 Arg2:E56 R84 MODIFY Arg1:T120 Arg2:E60 R85 SUB_PROCEDURE Arg1:E58 Arg2:E56 T121 Shape 2188 2197 elongated T122 Shape 2202 2207 plump R86 MODIFY Arg1:T121 Arg2:E58 R87 MODIFY Arg1:T122 Arg2:E58 T123 Lab_value 2215 2304 cells blended progressively with areas of less intense cellular mesenchymal proliferation R88 MODIFY Arg1:T123 Arg2:E56 T124 Detailed_description 2315 2350 relatively acellular, fibrous septa R89 MODIFY Arg1:T124 Arg2:T123 T125 Diagnostic_procedure 2352 2359 Osteoid E61 Diagnostic_procedure:T125 R90 SUB_PROCEDURE Arg1:E61 Arg2:E56 T126 Lab_value 2364 2371 present R91 MODIFY Arg1:T126 Arg2:E61 T127 Detailed_description 2379 2410 within the primitive mesenchyme T128 Detailed_description 2412 2451 near the fibrous septa or pseudocapsule T129 Detailed_description 2456 2494 admixed within the epithelial elements R92 MODIFY Arg1:T129 Arg2:T126 R93 MODIFY Arg1:T127 Arg2:T126 R94 MODIFY Arg1:T128 Arg2:T126 T130 Lab_value 2519 2565 cells morphologically identical to osteoblasts T131 Diagnostic_procedure 2496 2508 Osteoid foci E62 Diagnostic_procedure:T131 R95 SUB_PROCEDURE Arg1:E62 Arg2:E61 R96 MODIFY Arg1:T130 Arg2:E62 T132 Diagnostic_procedure 2580 2607 immunohistochemistry stains E63 Diagnostic_procedure:T132 T133 Diagnostic_procedure 2629 2639 hepatocyte E64 Diagnostic_procedure:T133 T134 Diagnostic_procedure 2641 2646 β-HCG E65 Diagnostic_procedure:T134 T135 Diagnostic_procedure 2648 2651 AFP E66 Diagnostic_procedure:T135 T136 Diagnostic_procedure 2653 2661 vimentin E67 Diagnostic_procedure:T136 T137 Diagnostic_procedure 2663 2666 CK7 E68 Diagnostic_procedure:T137 T138 Diagnostic_procedure 2668 2672 CK19 E69 Diagnostic_procedure:T138 T139 Diagnostic_procedure 2674 2678 CD56 E70 Diagnostic_procedure:T139 T140 Diagnostic_procedure 2683 2692 β-catenin E71 Diagnostic_procedure:T140 T141 Diagnostic_procedure 2712 2715 CEA E72 Diagnostic_procedure:T141 T142 Lab_value 2697 2707 negativity R97 MODIFY Arg1:T142 Arg2:E72 T143 Lab_value 2615 2625 expression R98 MODIFY Arg1:T143 Arg2:E64 R99 MODIFY Arg1:T143 Arg2:E65 R100 MODIFY Arg1:T143 Arg2:E66 R101 MODIFY Arg1:T143 Arg2:E67 R102 MODIFY Arg1:T143 Arg2:E68 R103 MODIFY Arg1:T143 Arg2:E69 R104 MODIFY Arg1:T143 Arg2:E70 R105 MODIFY Arg1:T143 Arg2:E71 R106 SUB_PROCEDURE Arg1:E64 Arg2:E63 R107 SUB_PROCEDURE Arg1:E65 Arg2:E63 R108 SUB_PROCEDURE Arg1:E66 Arg2:E63 R109 SUB_PROCEDURE Arg1:E67 Arg2:E63 R110 SUB_PROCEDURE Arg1:E68 Arg2:E63 R111 SUB_PROCEDURE Arg1:E69 Arg2:E63 R112 SUB_PROCEDURE Arg1:E70 Arg2:E63 R113 SUB_PROCEDURE Arg1:E71 Arg2:E63 R114 SUB_PROCEDURE Arg1:E72 Arg2:E63 T144 Disease_disorder 2752 2766 hepatoblastoma E73 Disease_disorder:T144 T145 Detailed_description 2741 2751 Metastatic R115 MODIFY Arg1:T145 Arg2:E73 T146 Diagnostic_procedure 2784 2806 histologic examination E74 Diagnostic_procedure:T146 T147 Diagnostic_procedure 2812 2839 immunohistochemistry stains E75 Diagnostic_procedure:T147 T148 Clinical_event 2954 2963 Follow-up E76 Clinical_event:T148 T149 Biological_structure 2964 2973 abdominal T150 Diagnostic_procedure 2974 2976 CT E77 Diagnostic_procedure:T150 R116 MODIFY Arg1:T149 Arg2:E77 T151 Date 2992 3005 1 month after E78 Date:T151 T152 Sign_symptom 3081 3085 mass E79 Sign_symptom:T152 T153 Detailed_description 3069 3080 soft tissue T154 Detailed_description 3052 3068 subtle enhancing T155 Distance 3039 3045 1.7 cm T156 Detailed_description 3027 3038 newly onset R117 MODIFY Arg1:T153 Arg2:E79 R118 MODIFY Arg1:T154 Arg2:E79 R119 MODIFY Arg1:T155 Arg2:E79 R120 MODIFY Arg1:T156 Arg2:E79 T157 Biological_structure 3089 3100 splenic bed R121 MODIFY Arg1:T157 Arg2:E79 T158 Diagnostic_procedure 3106 3134 positron emission tomography E80 Diagnostic_procedure:T158 T159 Diagnostic_procedure 3136 3139 PET E81 Diagnostic_procedure:T159 R122 IDENTICAL Arg1:E81 Arg2:E80 T160 Sign_symptom 3161 3167 uptake E82 Sign_symptom:T160 T161 Detailed_description 3157 3160 FDG T162 Detailed_description 3148 3156 multiple R123 MODIFY Arg1:T162 Arg2:E82 R124 MODIFY Arg1:T161 Arg2:E82 T163 Lab_value 3168 3182 max SUV > 3.80 R125 MODIFY Arg1:T163 Arg2:E82 T164 Biological_structure 3225 3232 abdomen T165 Detailed_description 3187 3197 left upper T166 Detailed_description 3202 3216 lower quadrant R126 MODIFY Arg1:T166 Arg2:T164 R127 MODIFY Arg1:T165 Arg2:T164 R128 MODIFY Arg1:T164 Arg2:E82 T167 Biological_structure 3234 3281 paralumbar area including right subphrenic area R129 MODIFY Arg1:T167 Arg2:E82 T168 Clinical_event 3298 3307 Follow-up E83 Clinical_event:T168 T169 Diagnostic_procedure 3308 3311 AFP E84 Diagnostic_procedure:T169 T170 Lab_value 3316 3328 162.69 ng/mL R130 MODIFY Arg1:T170 Arg2:E84 T171 Medication 3339 3351 chemotherapy E85 Medication:T171 T172 Detailed_description 3330 3338 Systemic R131 MODIFY Arg1:T172 Arg2:E85 T173 Medication 3365 3374 cisplatin E86 Medication:T173 T174 Dosage 3376 3384 60 mg/m2 R132 MODIFY Arg1:T174 Arg2:E86 T175 Medication 3387 3401 5-fluorourasil E87 Medication:T175 T176 Medication 3403 3407 5-FU E88 Medication:T176 R133 IDENTICAL Arg1:E88 Arg2:E87 T177 Dosage 3410 3419 600 mg/m2 R134 MODIFY Arg1:T177 Arg2:E87 T178 Medication 3422 3433 vincristine E89 Medication:T178 T179 Dosage 3435 3444 1.5 mg/m2 R135 MODIFY Arg1:T179 Arg2:E89 T180 Frequency 3456 3464 3 cycles T181 Frequency 3491 3503 every 4 week R136 MODIFY Arg1:T180 Arg2:E85 R137 MODIFY Arg1:T181 Arg2:E85 R138 SUB_PROCEDURE Arg1:E86 Arg2:E85 R139 SUB_PROCEDURE Arg1:E87 Arg2:E85 R140 SUB_PROCEDURE Arg1:E89 Arg2:E85 T182 Medication 3505 3514 Entecavir E90 Medication:T182 T183 Dosage 3515 3521 0.5 mg R141 MODIFY Arg1:T183 Arg2:E90 T184 Medication 3543 3559 chemoprophylaxis E91 Medication:T184 R142 SUB_PROCEDURE Arg1:E90 Arg2:E91 T185 Disease_disorder 3563 3566 CHB E92 Disease_disorder:T185 A1 POLARITY E92 NEG #3 AnnotatorNotes E92 Chronic hepatitis B T186 Clinical_event 3602 3611 follow-up E93 Clinical_event:T186 T187 Diagnostic_procedure 3622 3624 CT E94 Diagnostic_procedure:T187 T188 Diagnostic_procedure 3629 3632 PET E95 Diagnostic_procedure:T188 T189 Biological_structure 3612 3621 abdominal R143 MODIFY Arg1:T189 Arg2:E94 T190 Sign_symptom 3685 3695 metastasis E96 Sign_symptom:T190 A2 TREND E96 INC T191 Detailed_description 3660 3668 multiple T192 Biological_structure 3669 3684 intraperitoneal R144 MODIFY Arg1:T192 Arg2:E96 R145 MODIFY Arg1:T191 Arg2:E96 T193 Sign_symptom 3733 3738 fluid E97 Sign_symptom:T193 T194 Biological_structure 3717 3732 intraperitoneal R146 MODIFY Arg1:T194 Arg2:E97 T195 Severity 3701 3713 large amount R147 MODIFY Arg1:T195 Arg2:E97 T196 Diagnostic_procedure 3765 3768 AFP E98 Diagnostic_procedure:T196 T197 Lab_value 3781 3790 increased R148 MODIFY Arg1:T197 Arg2:E98 T198 Lab_value 3794 3803 254 ng/mL R149 MODIFY Arg1:T198 Arg2:E98 T199 Medication 3808 3820 chemotherapy E99 Medication:T199 T200 Medication 3844 3855 carboplatin E100 Medication:T200 T201 Lab_value 3857 3866 350 mg/m2 R150 MODIFY Arg1:T201 Arg2:E100 T202 Medication 3873 3884 doxorubicin E101 Medication:T202 T203 Lab_value 3886 3894 30 mg/m2 R151 MODIFY Arg1:T203 Arg2:E101 T204 Frequency 3896 3909 every 3 weeks R152 MODIFY Arg1:T204 Arg2:E99 R153 SUB_PROCEDURE Arg1:E100 Arg2:E99 R154 SUB_PROCEDURE Arg1:E101 Arg2:E99 T205 Sign_symptom 3935 3946 neutropenia E102 Sign_symptom:T205 T206 Medication 4013 4050 granulocyte colony-stimulating factor E103 Medication:T206 T207 Medication 4052 4057 G-CSF E104 Medication:T207 R155 IDENTICAL Arg1:E104 Arg2:E103 T208 Sign_symptom 3974 3983 recovered E105 Sign_symptom:T208 T209 Diagnostic_procedure 4126 4129 AFP E106 Diagnostic_procedure:T209 T210 Clinical_event 3755 3764 follow-up E107 Clinical_event:T210 T211 Clinical_event 4116 4125 follow-up E108 Clinical_event:T211 T212 Lab_value 4134 4143 increased R156 MODIFY Arg1:T212 Arg2:E106 T213 Lab_value 4144 4157 1510.19 ng/mL R157 MODIFY Arg1:T213 Arg2:E106 T214 Diagnostic_procedure 4173 4175 CT E109 Diagnostic_procedure:T214 T215 Biological_structure 4163 4172 abdominal R158 MODIFY Arg1:T215 Arg2:E109 T216 Sign_symptom 4203 4210 ascites E110 Sign_symptom:T216 A3 TREND E110 DEC T217 Medication 4287 4299 chemotherapy E111 Medication:T217 T218 Clinical_event 4340 4349 follow-up E112 Clinical_event:T218 T219 Biological_structure 4350 4359 abdominal T220 Diagnostic_procedure 4360 4362 CT E113 Diagnostic_procedure:T220 T221 Sign_symptom 4423 4429 masses E114 Sign_symptom:T221 T222 Detailed_description 4412 4422 metastatic T223 Biological_structure 4396 4411 intraperitoneal T224 Detailed_description 4387 4395 multiple R159 MODIFY Arg1:T222 Arg2:E114 R160 MODIFY Arg1:T223 Arg2:E114 R161 MODIFY Arg1:T224 Arg2:E114 T225 Sign_symptom 4455 4465 metastasis E115 Sign_symptom:T225 T226 Biological_structure 4447 4454 hepatic R162 MODIFY Arg1:T226 Arg2:E115 T227 Sign_symptom 4502 4507 fluid E116 Sign_symptom:T227 T228 Biological_structure 4486 4501 intraperitoneal R163 MODIFY Arg1:T228 Arg2:E116 T229 Severity 4470 4482 large amount R164 MODIFY Arg1:T229 Arg2:E116 T230 Diagnostic_procedure 4530 4542 paracentesis E117 Diagnostic_procedure:T230 T231 Diagnostic_procedure 4568 4584 white blood cell E118 Diagnostic_procedure:T231 T232 Lab_value 4585 4592 310/mm3 R165 MODIFY Arg1:T232 Arg2:E118 T233 Diagnostic_procedure 4594 4598 poly E119 Diagnostic_procedure:T233 T234 Diagnostic_procedure 4604 4609 lymph E120 Diagnostic_procedure:T234 T235 Lab_value 4599 4602 20% T236 Lab_value 4610 4613 80% R166 MODIFY Arg1:T236 Arg2:E120 R167 MODIFY Arg1:T235 Arg2:E119 R168 SUB_PROCEDURE Arg1:E119 Arg2:E118 R169 SUB_PROCEDURE Arg1:E120 Arg2:E118 T237 Diagnostic_procedure 4616 4623 protein E121 Diagnostic_procedure:T237 T238 Lab_value 4624 4632 3.6 g/dL R170 MODIFY Arg1:T238 Arg2:E121 T239 Diagnostic_procedure 4637 4644 albumin E122 Diagnostic_procedure:T239 T240 Lab_value 4645 4653 2.3 g/dL R171 MODIFY Arg1:T240 Arg2:E122 T241 Diagnostic_procedure 4657 4679 ascitic fluid analysis E123 Diagnostic_procedure:T241 R172 SUB_PROCEDURE Arg1:E118 Arg2:E123 R173 SUB_PROCEDURE Arg1:E121 Arg2:E123 R174 SUB_PROCEDURE Arg1:E122 Arg2:E123 T242 Diagnostic_procedure 4685 4698 serum albumin E124 Diagnostic_procedure:T242 T243 Lab_value 4703 4711 3.1 g/dL R175 MODIFY Arg1:T243 Arg2:E124 T244 Diagnostic_procedure 4716 4746 serum-ascites albumin gradient E125 Diagnostic_procedure:T244 T245 Diagnostic_procedure 4748 4752 SAAG E126 Diagnostic_procedure:T245 R176 IDENTICAL Arg1:E126 Arg2:E125 T246 Lab_value 4758 4766 0.8 g/dL R177 MODIFY Arg1:T246 Arg2:E125 T247 Diagnostic_procedure 4772 4793 AFB stain and culture E127 Diagnostic_procedure:T247 T248 Lab_value 4803 4811 negative R178 MODIFY Arg1:T248 Arg2:E127 T249 Detailed_description 4815 4828 ascitic fluid R179 MODIFY Arg1:T249 Arg2:E127 T250 Diagnostic_procedure 4834 4837 AFP E128 Diagnostic_procedure:T250 T251 Detailed_description 4859 4864 serum R180 MODIFY Arg1:T251 Arg2:E128 T252 Lab_value 4842 4855 6881.93 ng/mL R181 MODIFY Arg1:T252 Arg2:E128 T253 Disease_disorder 4889 4903 carcinomatosis E129 Disease_disorder:T253 T254 Biological_structure 4878 4888 peritoneal R182 MODIFY Arg1:T254 Arg2:E129 T255 Therapeutic_procedure 4927 4950 conservative treatments E130 Therapeutic_procedure:T255 T256 Therapeutic_procedure 4981 5005 therapeutic paracentesis E131 Therapeutic_procedure:T256 T257 Duration 5010 5017 1 month E132 Duration:T257 T258 Detailed_description 4972 4980 repeated R183 MODIFY Arg1:T258 Arg2:E131 R184 AFTER Arg1:E1 Arg2:E2 * OVERLAP E2 E3 R185 BEFORE Arg1:E3 Arg2:E4 * OVERLAP E4 E5 E6 E7 E8 E24 E33 E35 E37 E38 R186 BEFORE Arg1:E38 Arg2:E39 * OVERLAP E39 E40 R187 BEFORE Arg1:E40 Arg2:E41 * OVERLAP E41 E42 R188 BEFORE Arg1:E42 Arg2:E43 * OVERLAP E43 E44 E47 R189 SUB_PROCEDURE Arg1:E45 Arg2:E44 R190 BEFORE Arg1:E47 Arg2:E48 * OVERLAP E48 E49 E50 E51 E52 E53 R191 BEFORE Arg1:E53 Arg2:E54 * OVERLAP E73 E74 E75 E54 E56 E63 R193 BEFORE Arg1:E75 Arg2:E76 * OVERLAP E76 E77 E78 E79 E80 E82 R192 BEFORE Arg1:E82 Arg2:E83 * OVERLAP E83 E84 R194 BEFORE Arg1:E84 Arg2:E85 * OVERLAP E85 E90 E92 R195 BEFORE Arg1:E92 Arg2:E93 * OVERLAP E93 E94 E95 E96 E97 R196 BEFORE Arg1:E97 Arg2:E107 * OVERLAP E107 E98 R197 BEFORE Arg1:E98 Arg2:E99 R198 BEFORE Arg1:E99 Arg2:E102 R199 BEFORE Arg1:E102 Arg2:E105 * OVERLAP E105 E103 R200 BEFORE Arg1:E103 Arg2:E108 * OVERLAP E108 E106 E109 E110 R201 BEFORE Arg1:E110 Arg2:E111 R202 BEFORE Arg1:E111 Arg2:E112 * OVERLAP E112 E113 E114 E115 E116 E117 E123 E124 E125 E127 E128 R203 BEFORE Arg1:E128 Arg2:E129 * OVERLAP E129 E130 E131 E132 R204 BEFORE Arg1:E132 Arg2:E57