[fd8900]: / processing / MACCROBAT / 26327988.ann

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T1	Age 2 13	66 year old
T2	History 29 42	history of UC
#1	AnnotatorNotes T2	ulcerative colitis
T3	Medication 54 64	mesalazine
E1	Medication:T3 
T4	Duration 65 78	since 5 years
E2	Duration:T4 
T5	Clinical_event 79 88	consulted
E3	Clinical_event:T5 
T6	Date 92 101	July 2012
E4	Date:T6 
T7	Sign_symptom 129 137	swelling
E5	Sign_symptom:T7 
T8	Detailed_description 116 128	erythematous
T9	Detailed_description 108 115	painful
R1	MODIFY Arg1:T8 Arg2:E5	
R2	MODIFY Arg1:T9 Arg2:E5	
T10	Biological_structure 145 167	back of the right hand
R3	MODIFY Arg1:T10 Arg2:E5	
T11	Diagnostic_procedure 173 196	bacteriological samples
E6	Diagnostic_procedure:T11 
T12	Lab_value 202 210	negative
R4	MODIFY Arg1:T12 Arg2:E6	
T13	Coreference 216 222	lesion
E7	Coreference:T13 
R5	IDENTICAL Arg1:E7 Arg2:E5	
T14	Medication 287 298	antibiotics
E8	Medication:T14 
T15	Medication 303 320	local antiseptics
E9	Medication:T15 
T16	Sign_symptom 329 340	improvement
E10	Sign_symptom:T16 
A1	POLARITY E10 NEG
T17	Sign_symptom 244 253	abscesses
E11	Sign_symptom:T17 
A2	POLARITY E11 UNCERTAIN
T18	Sign_symptom 427 448	centrifugal expansion
E12	Sign_symptom:T18 
T19	Detailed_description 411 426	vesiculobullous
T20	Detailed_description 398 410	erythematous
R6	MODIFY Arg1:T19 Arg2:E12	
R7	MODIFY Arg1:T20 Arg2:E12	
T21	Biological_structure 460 488	whole back of the right hand
R8	MODIFY Arg1:T21 Arg2:E12	
T22	Medication 514 533	various antibiotics
E13	Medication:T22 
T23	Frequency 497 510	several times
R9	MODIFY Arg1:T23 Arg2:E13	
T24	Diagnostic_procedure 550 556	Biopsy
E14	Diagnostic_procedure:T24 
T25	Lab_value 586 598	not specific
R10	MODIFY Arg1:T25 Arg2:E14	
T26	Date 603 615	October 2012
E15	Date:T26 
T27	Clinical_event 633 645	hospitalized
E16	Clinical_event:T27 
T28	Sign_symptom 650 655	fever
E17	Sign_symptom:T28 
T29	Sign_symptom 660 674	polyarthralgia
E18	Sign_symptom:T29 
T30	Sign_symptom 693 719	impaired general condition
E19	Sign_symptom:T30 
T31	Disease_disorder 740 750	UC disease
E20	Disease_disorder:T31 
T32	Detailed_description 730 739	quiescent
R11	MODIFY Arg1:T32 Arg2:E20	
T33	Diagnostic_procedure 756 772	skin examination
E21	Diagnostic_procedure:T33 
T34	Sign_symptom 795 801	plaque
E22	Sign_symptom:T34 
T35	Detailed_description 782 794	erythematous
R12	MODIFY Arg1:T35 Arg2:E22	
T36	Distance 805 810	10 cm
R13	MODIFY Arg1:T36 Arg2:E22	
T37	Detailed_description 831 844	raised border
T38	Detailed_description 849 858	vesicules
R14	MODIFY Arg1:T37 Arg2:E22	
R15	MODIFY Arg1:T38 Arg2:E22	
T39	Biological_structure 871 893	back of the right hand
T40	Biological_structure 898 903	wrist
R16	MODIFY Arg1:T39 Arg2:E22	
R17	MODIFY Arg1:T40 Arg2:E22	
T41	Sign_symptom 959 965	plaque
E23	Sign_symptom:T41 
T42	Detailed_description 934 945	infiltrated
T43	Detailed_description 946 958	erythematous
R18	MODIFY Arg1:T43 Arg2:E23	
R19	MODIFY Arg1:T42 Arg2:E23	
T44	Biological_structure 973 982	right leg
R20	MODIFY Arg1:T44 Arg2:E23	
T45	Biological_structure 1041 1051	left ankle
R21	MODIFY Arg1:T45 Arg2:E23	
T46	Detailed_description 1006 1033	topped with a large pustule
R22	MODIFY Arg1:T46 Arg2:E23	
T47	Disease_disorder 1088 1120	biological inflammatory syndrome
E24	Disease_disorder:T47 
T48	Sign_symptom 1130 1142	leukocytosis
E25	Sign_symptom:T48 
T49	Detailed_description 1143 1159	with neutrophils
R23	MODIFY Arg1:T49 Arg2:E25	
T50	Severity 1125 1129	high
R24	MODIFY Arg1:T50 Arg2:E25	
T51	Diagnostic_procedure 1161 1168	Hepatic
E26	Diagnostic_procedure:T51 
T52	Diagnostic_procedure 1173 1188	renal functions
E27	Diagnostic_procedure:T52 
T53	Lab_value 1194 1200	normal
R25	MODIFY Arg1:T53 Arg2:E27	
R26	MODIFY Arg1:T53 Arg2:E26	
T54	Diagnostic_procedure 1202 1213	Skin biopsy
E28	Diagnostic_procedure:T54 
T55	Biological_structure 1228 1269	edge of the back of the closet right hand
R27	MODIFY Arg1:T55 Arg2:E28	
T56	Sign_symptom 1270 1289	ulcerated epidermis
E29	Sign_symptom:T56 
T57	Disease_disorder 1379 1381	PG
E30	Disease_disorder:T57 
#2	AnnotatorNotes E30	pyoderma gangrenosum
T58	Disease_disorder 1622 1624	SS
E31	Disease_disorder:T58 
#3	AnnotatorNotes E31	Sweet's Syndrome
T59	Sign_symptom 1358 1368	vasculitis
E32	Sign_symptom:T59 
T60	Detailed_description 1341 1357	leukocytoclastic
R28	MODIFY Arg1:T60 Arg2:E32	
T61	Detailed_description 1298 1335	dermis infiltrate rich in neutrophils
R29	MODIFY Arg1:T61 Arg2:E29	
T62	Diagnostic_procedure 1394 1408	Other biopsies
E33	Diagnostic_procedure:T62 
T63	Sign_symptom 1443 1450	plaques
E34	Sign_symptom:T63 
T64	Detailed_description 1430 1442	erythematous
T65	Detailed_description 1418 1429	infiltrated
R30	MODIFY Arg1:T64 Arg2:E34	
R31	MODIFY Arg1:T65 Arg2:E34	
T66	Biological_structure 1458 1463	ankle
R32	MODIFY Arg1:T66 Arg2:E34	
T67	Diagnostic_procedure 1480 1498	appearance of skin
E35	Diagnostic_procedure:T67 
T68	Lab_value 1473 1479	normal
R33	MODIFY Arg1:T68 Arg2:E35	
R34	SUB_PROCEDURE Arg1:E35 Arg2:E33	
T69	Sign_symptom 1500 1505	edema
E36	Sign_symptom:T69 
T70	Biological_structure 1513 1531	superficial dermis
R35	MODIFY Arg1:T70 Arg2:E36	
T71	Detailed_description 1544 1574	infiltrate rich in neutrophils
R36	MODIFY Arg1:T71 Arg2:T70	
T72	Sign_symptom 1583 1593	vasculitis
E37	Sign_symptom:T72 
A3	POLARITY E37 NEG
T73	Medication 1637 1651	Corticosteroid
E38	Medication:T73 
T74	Medication 1684 1696	prednisolone
E39	Medication:T74 
R37	SUB_PROCEDURE Arg1:E39 Arg2:E38	
T75	Dosage 1710 1718	1mg/Kg/j
R38	MODIFY Arg1:T75 Arg2:E39	
T76	Date 1745 1769	since day 7 of treatment
E40	Date:T76 
T77	Sign_symptom 1777 1807	desinfiltration of the plaques
E41	Sign_symptom:T77 
T78	Sign_symptom 1824 1857	recovery of the general condition
E42	Sign_symptom:T78 
T79	Disease_disorder 1879 1911	biological inflammatory syndrome
E43	Disease_disorder:T79 
A4	POLARITY E43 NEG
R39	BEFORE Arg1:E1 Arg2:E3	
R40	MODIFY Arg1:E2 Arg2:E1	
*	OVERLAP E3 E4 E5 E6 E11 E8 E9 E10 E12 E13 E14
R41	BEFORE Arg1:E14 Arg2:E15	
*	OVERLAP E15 E16 E17 E18 E19 E20 E21 E22 E23 E24 E25 E26 E27 E28 E29 E32 E30 E33 E34 E35 E36 E37 E31
R42	BEFORE Arg1:E31 Arg2:E38	
R43	BEFORE Arg1:E38 Arg2:E40	
*	OVERLAP E40 E41 E42 E43