--- a
+++ b/processing/MACCROBAT/24526194.ann
@@ -0,0 +1,211 @@
+T1	Age 2 13	35-year-old
+T2	Sex 14 19	woman
+T3	Clinical_event 20 29	presented
+E1	Clinical_event:T3 
+T4	Nonbiological_location 37 65	medical emergency department
+R1	MODIFY Arg1:T4 Arg2:E1	
+T5	Sign_symptom 81 86	fever
+E2	Sign_symptom:T5 
+T6	Severity 71 80	low-grade
+R2	MODIFY Arg1:T6 Arg2:E2	
+T7	Duration 91 98	3 weeks
+E3	Duration:T7 
+T8	Sign_symptom 100 108	vomiting
+E4	Sign_symptom:T8 
+T9	Duration 113 119	1 week
+E5	Duration:T9 
+T10	Sign_symptom 124 130	anuria
+E6	Sign_symptom:T10 
+T11	Duration 135 141	3 days
+E7	Duration:T11 
+T12	Sign_symptom 161 168	dysuria
+E8	Sign_symptom:T12 
+T13	Sign_symptom 173 187	breathlessness
+E9	Sign_symptom:T13 
+T14	Duration 192 198	1 week
+E10	Duration:T14 
+T15	History 210 329	no history of decreased urine output, dialysis, effort intolerance, chest pain or palpitation, dyspnoea and weight loss
+T16	Sign_symptom 224 246	decreased urine output
+E11	Sign_symptom:T16 
+A1	POLARITY E11 NEG
+T17	Therapeutic_procedure 248 256	dialysis
+E12	Therapeutic_procedure:T17 
+A2	POLARITY E12 NEG
+T18	Sign_symptom 258 276	effort intolerance
+E13	Sign_symptom:T18 
+A3	POLARITY E13 NEG
+T19	Sign_symptom 284 288	pain
+E14	Sign_symptom:T19 
+A4	POLARITY E14 NEG
+T20	Biological_structure 278 283	chest
+R3	MODIFY Arg1:T20 Arg2:E14	
+T21	Sign_symptom 292 303	palpitation
+E15	Sign_symptom:T21 
+A5	POLARITY E15 NEG
+T22	Sign_symptom 305 313	dyspnoea
+E16	Sign_symptom:T22 
+A6	POLARITY E16 NEG
+T23	Sign_symptom 318 329	weight loss
+E17	Sign_symptom:T23 
+A7	POLARITY E17 NEG
+T24	Diagnostic_procedure 331 348	Menstrual history
+E18	Diagnostic_procedure:T24 
+T25	Lab_value 353 372	within normal limit
+R4	MODIFY Arg1:T25 Arg2:E18	
+T26	Sign_symptom 412 428	loss of appetite
+E19	Sign_symptom:T26 
+A8	TREND E19 INC
+T27	Lab_value 390 411	gradually progressive
+R5	MODIFY Arg1:T27 Arg2:E19	
+T28	Family_history 454 530	smoky urine in her younger brother in his childhood, who died in an accident
+T29	Subject 473 488	younger brother
+T30	Detailed_description 511 530	died in an accident
+T31	Detailed_description 454 465	smoky urine
+R6	MODIFY Arg1:T30 Arg2:T29	
+R7	MODIFY Arg1:T31 Arg2:T29	
+T32	Diagnostic_procedure 535 549	general survey
+E20	Diagnostic_procedure:T32 
+T33	Sign_symptom 610 617	febrile
+E21	Sign_symptom:T33 
+T34	Sign_symptom 596 605	dyspnoeic
+E22	Sign_symptom:T34 
+T35	Sign_symptom 567 576	conscious
+E23	Sign_symptom:T35 
+T36	Sign_symptom 581 586	alert
+E24	Sign_symptom:T36 
+T37	Sign_symptom 626 632	pallor
+E25	Sign_symptom:T37 
+T38	Sign_symptom 661 667	oedema
+E26	Sign_symptom:T38 
+T39	Biological_structure 655 660	pedal
+R8	MODIFY Arg1:T39 Arg2:E26	
+T40	Severity 650 654	mild
+R9	MODIFY Arg1:T40 Arg2:E26	
+T41	Severity 619 625	Severe
+R10	MODIFY Arg1:T41 Arg2:E25	
+T42	Diagnostic_procedure 669 683	Blood pressure
+E27	Diagnostic_procedure:T42 
+T43	Lab_value 688 701	180/100 mm Hg
+R11	MODIFY Arg1:T43 Arg2:E27	
+T44	Diagnostic_procedure 706 716	pulse rate
+E28	Diagnostic_procedure:T44 
+T45	Lab_value 720 727	116/min
+T46	Lab_value 728 735	regular
+R12	MODIFY Arg1:T46 Arg2:E28	
+R13	MODIFY Arg1:T45 Arg2:E28	
+T47	Sign_symptom 752 760	jaundice
+E29	Sign_symptom:T47 
+A9	POLARITY E29 NEG
+T48	Sign_symptom 771 779	cyanosis
+E30	Sign_symptom:T48 
+A10	POLARITY E30 NEG
+T49	Detailed_description 762 770	clubbing
+R14	MODIFY Arg1:T49 Arg2:E30	
+T50	Disease_disorder 783 798	lymphadenopathy
+E31	Disease_disorder:T50 
+A11	POLARITY E31 NEG
+T51	Diagnostic_procedure 810 830	Physical examination
+E32	Diagnostic_procedure:T51 
+T52	Sign_symptom 866 878	crepitations
+E33	Sign_symptom:T52 
+T53	Detailed_description 850 865	end-inspiratory
+T54	Biological_structure 840 849	bibasilar
+R15	MODIFY Arg1:T54 Arg2:E33	
+R16	MODIFY Arg1:T53 Arg2:E33	
+T55	Biological_structure 882 887	lungs
+R17	MODIFY Arg1:T55 Arg2:E33	
+T56	Biological_structure 892 902	suprapubic
+T57	Sign_symptom 903 913	tenderness
+E34	Sign_symptom:T57 
+R18	MODIFY Arg1:T56 Arg2:E34	
+T58	Sign_symptom 950 957	ascites
+E35	Sign_symptom:T58 
+A12	POLARITY E35 NEG
+T59	Sign_symptom 928 946	hepatosplenomegaly
+E36	Sign_symptom:T59 
+A13	POLARITY E36 NEG
+T60	Diagnostic_procedure 959 978	Cardiac examination
+E37	Diagnostic_procedure:T60 
+T61	Lab_value 983 989	normal
+R19	MODIFY Arg1:T61 Arg2:E37	
+T62	Severity 1013 1019	severe
+T63	Sign_symptom 1030 1042	hearing loss
+E38	Sign_symptom:T63 
+T64	Biological_structure 1093 1098	fundi
+T65	Sign_symptom 1116 1120	pale
+E39	Sign_symptom:T65 
+T66	Detailed_description 1104 1115	bilaterally
+R20	MODIFY Arg1:T66 Arg2:E39	
+R21	MODIFY Arg1:T64 Arg2:E39	
+T67	Detailed_description 1020 1029	bilateral
+R22	MODIFY Arg1:T67 Arg2:E38	
+R23	MODIFY Arg1:T62 Arg2:E38	
+A14	TREND E38 INC
+T68	Lab_value 1054 1075	gradually progressive
+T69	Duration 1080 1087	5 years
+E40	Duration:T69 
+R24	MODIFY Arg1:T68 Arg2:E38	
+R25	BEFORE Arg1:E40 Arg2:E38	
+T70	Clinical_event 1138 1146	referred
+E41	Clinical_event:T70 
+T71	Nonbiological_location 1154 1181	department of ophthalmology
+R26	MODIFY Arg1:T71 Arg2:E41	
+T72	Diagnostic_procedure 1202 1217	eye examination
+E42	Diagnostic_procedure:T72 
+T73	Diagnostic_procedure 1223 1236	visual acuity
+E43	Diagnostic_procedure:T73 
+T74	Lab_value 1255 1259	6/18
+T75	Biological_structure 1263 1272	both eyes
+R27	MODIFY Arg1:T75 Arg2:E43	
+R28	MODIFY Arg1:T74 Arg2:E43	
+T76	Sign_symptom 1289 1307	lenticular opacity
+E44	Sign_symptom:T76 
+A15	POLARITY E44 NEG
+T77	Diagnostic_procedure 1309 1330	Slit-lamp examination
+E45	Diagnostic_procedure:T77 
+T78	Detailed_description 1338 1347	bilateral
+T79	Sign_symptom 1348 1368	anterior lentiglobus
+E46	Sign_symptom:T79 
+T80	Sign_symptom 1385 1405	posterior lenticonus
+E47	Sign_symptom:T80 
+R29	MODIFY Arg1:T78 Arg2:E46	
+T81	Diagnostic_procedure 1433 1447	ophthalmoscopy
+E48	Diagnostic_procedure:T81 
+T82	Detailed_description 1418 1432	Distant direct
+R30	MODIFY Arg1:T82 Arg2:E48	
+T83	Sign_symptom 1457 1473	oil droplet sign
+E49	Sign_symptom:T83 
+T84	Sign_symptom 1520 1530	lenticonus
+E50	Sign_symptom:T84 
+T85	Sign_symptom 1670 1690	hypertensive changes
+E51	Sign_symptom:T85 
+T86	Sign_symptom 1638 1655	blot haemorrhages
+E52	Sign_symptom:T86 
+T87	Detailed_description 1634 1637	few
+R31	MODIFY Arg1:T87 Arg2:E52	
+T88	Sign_symptom 1589 1607	lesion-like flecks
+E53	Sign_symptom:T88 
+T89	Color 1573 1588	yellowish white
+T90	Detailed_description 1564 1572	multiple
+R32	MODIFY Arg1:T89 Arg2:E53	
+R33	MODIFY Arg1:T90 Arg2:E53	
+T91	Biological_structure 1537 1554	peripheral retina
+R34	MODIFY Arg1:T91 Arg2:E53	
+T92	Biological_structure 1615 1628	mid-periphery
+R35	MODIFY Arg1:T92 Arg2:E53	
+R36	AFTER Arg1:E1 Arg2:E2	
+*	OVERLAP E2 E3
+R37	BEFORE Arg1:E3 Arg2:E4	
+*	OVERLAP E4 E5
+R38	BEFORE Arg1:E5 Arg2:E6	
+*	OVERLAP E6 E7
+R39	AFTER Arg1:E7 Arg2:E8	
+*	OVERLAP E8 E9 E10
+R40	AFTER Arg1:E10 Arg2:E11	
+*	OVERLAP E11 E12 E13 E14 E15 E16 E17 E18 E19
+R41	BEFORE Arg1:E19 Arg2:E20	
+*	OVERLAP E20 E23 E24 E22 E21 E25 E26 E27 E28 E29 E30 E31 E32 E33 E34 E36 E35 E37
+R42	AFTER Arg1:E37 Arg2:E38	
+R43	BEFORE Arg1:E38 Arg2:E39	
+R44	BEFORE Arg1:E39 Arg2:E41	
+*	OVERLAP E41 E42 E43 E44 E45 E46 E47 E48 E49 E50 E53 E52 E51