211 lines (210 with data), 7.1 kB

T1	Subject 79 86	parents
T2	Personal_background 71 78	British
#1	AnnotatorNotes T2	Patient inherits ethnicity value
T3	Personal_background 65 70	white
#2	AnnotatorNotes T3	Patient inherits ethnicity value
T4	Detailed_description 45 63	non-consanguineous
T5	Detailed_description 37 44	healthy
R1	MODIFY Arg1:T4 Arg2:T1	
R2	MODIFY Arg1:T5 Arg2:T1	
T6	Sex 11 14	boy
T7	Age 5 10	young
T8	Clinical_event 95 99	born
E1	Clinical_event:T8 
T9	Detailed_description 100 107	at term
R3	MODIFY Arg1:T9 Arg2:E1	
T10	Weight 151 157	3132 g
T11	Detailed_description 121 141	uneventful pregnancy
R4	MODIFY Arg1:T11 Arg2:E1	
T12	Diagnostic_procedure 178 195	Early development
E2	Diagnostic_procedure:T12 
T13	Lab_value 214 220	normal
R5	MODIFY Arg1:T13 Arg2:E2	
T14	Date 225 254	approximately 6 months of age
E3	Date:T14 
T15	Sign_symptom 281 294	eye deviation
E4	Sign_symptom:T15 
T16	Detailed_description 268 280	tonic upward
R6	MODIFY Arg1:T16 Arg2:E4	
T17	Sign_symptom 311 318	flexion
E5	Sign_symptom:T17 
T18	Disease_disorder 356 372	infantile spasms
E6	Disease_disorder:T18 
T19	Biological_structure 326 330	arms
T20	Biological_structure 335 339	neck
R7	MODIFY Arg1:T19 Arg2:E5	
R8	MODIFY Arg1:T20 Arg2:E5	
T21	Diagnostic_procedure 377 398	electroencephalograph
E7	Diagnostic_procedure:T21 
T22	Diagnostic_procedure 400 403	EEG
E8	Diagnostic_procedure:T22 
R9	IDENTICAL Arg1:E8 Arg2:E7	
T23	Lab_value 422 438	grossly abnormal
R10	MODIFY Arg1:T23 Arg2:E7	
T24	Sign_symptom 440 454	hypsarrhythmia
E9	Sign_symptom:T24 
T25	Disease_disorder 494 507	West Syndrome
E10	Disease_disorder:T25 
T26	Diagnostic_procedure 517 520	MRI
E11	Diagnostic_procedure:T26 
T27	Biological_structure 509 516	Cranial
R11	MODIFY Arg1:T27 Arg2:E11	
T28	Lab_value 537 543	normal
R12	MODIFY Arg1:T28 Arg2:E11	
T29	Medication 545 557	Prednisolone
E12	Medication:T29 
T30	Medication 611 619	Steroids
E13	Medication:T30 
T31	Duration 632 644	over 6 weeks
E14	Duration:T31 
R13	MODIFY Arg1:E14 Arg2:E13	
A1	TREND E13 DEC
T32	Sign_symptom 661 668	seizure
E15	Sign_symptom:T32 
A2	POLARITY E15 NEG
T33	Duration 680 696	further 6 months
E16	Duration:T33 
R14	MODIFY Arg1:E16 Arg2:E15	
T34	Sign_symptom 589 597	seizures
E17	Sign_symptom:T34 
A3	POLARITY E17 MAYBE_NEG
T35	Date 705 718	age of 1 year
E18	Date:T35 
T36	Diagnostic_procedure 751 773	developmental progress
E19	Diagnostic_procedure:T36 
T37	Lab_value 778 798	not being maintained
R15	MODIFY Arg1:T37 Arg2:E19	
T38	Diagnostic_procedure 844 863	developmental stage
E20	Diagnostic_procedure:T38 
T39	Lab_value 834 843	6–8 month
R16	MODIFY Arg1:T39 Arg2:E20	
T40	Date 891 915	after his first birthday
E21	Date:T40 
T41	Sign_symptom 865 873	Seizures
E22	Sign_symptom:T41 
T42	Detailed_description 925 934	prolonged
T43	Detailed_description 936 944	frequent
T44	Detailed_description 949 966	on occasion focal
R17	MODIFY Arg1:T42 Arg2:E22	
R18	MODIFY Arg1:T43 Arg2:E22	
R19	MODIFY Arg1:T44 Arg2:E22	
T45	Biological_structure 982 991	right arm
T46	Biological_structure 993 996	leg
T47	Biological_structure 1001 1019	right side of face
R20	MODIFY Arg1:T45 Arg2:T44	
R21	MODIFY Arg1:T46 Arg2:T44	
R22	MODIFY Arg1:T47 Arg2:T44	
T48	Medication 1021 1031	Clonazepam
E23	Medication:T48 
T49	Sign_symptom 1049 1056	seizure
E24	Sign_symptom:T49 
A4	TREND E24 DEC
R23	CAUSE Arg1:E12 Arg2:E17	
R24	CAUSE Arg1:E23 Arg2:E24	
T50	Disease_disorder 1089 1097	epilepsy
E25	Disease_disorder:T50 
T51	Detailed_description 1109 1169	refractory to various combinations of anticonvulsant therapy
R25	MODIFY Arg1:T51 Arg2:E25	
T52	Sign_symptom 1181 1189	seizures
E26	Sign_symptom:T52 
T53	Detailed_description 1171 1180	Prolonged
R26	MODIFY Arg1:T53 Arg2:E26	
T54	Detailed_description 1193 1209	more than 60 min
R27	MODIFY Arg1:T54 Arg2:E26	
T55	Diagnostic_procedure 1265 1281	neurodevelopment
E27	Diagnostic_procedure:T55 
T56	Lab_value 1238 1257	stepwise regression
R28	MODIFY Arg1:T56 Arg2:E27	
R29	CAUSE Arg1:E26 Arg2:E27	
T57	Disease_disorder 1329 1357	epilepsia partialis continua
E28	Disease_disorder:T57 
T58	Biological_structure 1372 1394	right side of his face
T59	Biological_structure 1396 1405	right arm
T60	Biological_structure 1410 1419	right leg
R30	MODIFY Arg1:T58 Arg2:E28	
R31	MODIFY Arg1:T59 Arg2:E28	
R32	MODIFY Arg1:T60 Arg2:E28	
T61	Sign_symptom 1283 1290	Seizure
E29	Sign_symptom:T61 
T62	Diagnostic_procedure 1525 1528	MRI
E30	Diagnostic_procedure:T62 
T63	Biological_structure 1517 1524	cranial
R33	MODIFY Arg1:T63 Arg2:E30	
T64	Date 1536 1559	age of 2 years 6 months
E31	Date:T64 
T65	Coreference 1489 1498	condition
E32	Coreference:T65 
R34	IDENTICAL Arg1:E32 Arg2:E28	
T66	Detailed_description 1463 1474	progressive
R35	MODIFY Arg1:T66 Arg2:E32	
T67	Sign_symptom 1446 1454	seizures
E33	Sign_symptom:T67 
T68	Detailed_description 1440 1445	focal
R36	MODIFY Arg1:T68 Arg2:E33	
T69	Diagnostic_procedure 1602 1605	MRI
E34	Diagnostic_procedure:T69 
T70	Sign_symptom 1652 1659	lesions
E35	Sign_symptom:T70 
T71	Biological_structure 1627 1651	subcortical white matter
R37	MODIFY Arg1:T71 Arg2:E35	
T72	Detailed_description 1615 1626	symmetrical
R38	MODIFY Arg1:T72 Arg2:E35	
T73	Sign_symptom 1674 1682	thinning
E36	Sign_symptom:T73 
T74	Biological_structure 1690 1730	anterior and genu of the corpus callosum
R39	MODIFY Arg1:T74 Arg2:E36	
T75	Diagnostic_procedure 1744 1755	examination
E37	Diagnostic_procedure:T75 
T78	Biological_structure 1806 1810	ears
T76	Biological_structure 1823 1833	nasal root
T77	Detailed_description 1817 1822	broad
R40	MODIFY Arg1:T77 Arg2:T76	
T79	Detailed_description 1787 1805	anteriorly rotated
T80	Shape 1780 1785	round
T81	Detailed_description 1773 1778	small
R41	MODIFY Arg1:T79 Arg2:T78	
R42	MODIFY Arg1:T80 Arg2:T78	
R43	MODIFY Arg1:T81 Arg2:T78	
R44	MODIFY Arg1:T76 Arg2:E37	
R45	MODIFY Arg1:T78 Arg2:E37	
T82	Diagnostic_procedure 1854 1870	visual awareness
E38	Diagnostic_procedure:T82 
T83	Sign_symptom 1875 1897	startled to loud noise
E39	Sign_symptom:T83 
T84	Lab_value 1851 1853	no
R46	MODIFY Arg1:T84 Arg2:E38	
T85	Diagnostic_procedure 1899 1903	Tone
E40	Diagnostic_procedure:T85 
#3	AnnotatorNotes E40	muscle tone?
T86	Lab_value 1908 1917	increased
T87	Biological_structure 1921 1932	all 4 limbs
R47	MODIFY Arg1:T87 Arg2:E40	
R48	MODIFY Arg1:T86 Arg2:E40	
T88	Sign_symptom 1938 1955	internal rotation
E41	Sign_symptom:T88 
T89	Biological_structure 1959 1980	both legs at the hips
R49	MODIFY Arg1:T89 Arg2:E41	
T90	Diagnostic_procedure 1982 1990	Reflexes
E42	Diagnostic_procedure:T90 
T91	Lab_value 1996 2016	pathologically brisk
R50	MODIFY Arg1:T91 Arg2:E42	
T92	Sign_symptom 2024 2039	myoclonic jerks
E43	Sign_symptom:T92 
T93	Detailed_description 2018 2023	Brief
R51	MODIFY Arg1:T93 Arg2:E43	
R52	BEFORE Arg1:E1 Arg2:E2	
R53	BEFORE Arg1:E2 Arg2:E3	
*	OVERLAP E3 E4 E5 E6 E7 E9 E10 E11 E12
R54	BEFORE Arg1:E12 Arg2:E13	
R55	BEFORE Arg1:E13 Arg2:E15	
R56	BEFORE Arg1:E15 Arg2:E18	
*	OVERLAP E18 E19 E20
R57	BEFORE Arg1:E20 Arg2:E22	
*	OVERLAP E22 E21
R58	BEFORE Arg1:E21 Arg2:E23	
R59	BEFORE Arg1:E23 Arg2:E25	
*	OVERLAP E25 E26
R60	BEFORE Arg1:E26 Arg2:E29	
*	OVERLAP E29 E28 E33
R61	BEFORE Arg1:E33 Arg2:E30	
*	OVERLAP E30 E31 E34 E35 E36 E37 E38 E39 E40 E41 E42 E43