--- a
+++ b/processing/MACCROBAT/23077697.txt
@@ -0,0 +1,15 @@
+A 76-year old woman presented with a 24-month history of enlarging mass involving the back history of trauma.
+Physical examination showed a mass of an 3x4 cm in diameter, localized in the right inter-scapular region.
+The mass was ulcerative helophytic, grayish in colour, hard in consistency and easily bleeding on manipulation.
+The remainder of the examination was unremarkable; no lymphadenopathy and no abdominal masses were felt.
+After resection, the histological examinations of the specimens have concluded for basal cell carcinoma.
+A local recurrence was observed 18 months later; the patient was admitted to our institution for Lumpectomy (Figure 1).
+Histopathological examination revealed a syringomatous pattern infiltrating the dermis (Figure 2, Figure 3), subcutis and skeletal muscle.
+The neoplastic epithelial cells were arranged in interconnecting cords with microcystic areas.
+Nests, cords, and tubules of the tumour extended into the dermis and into the adjacent muscle.
+Many lobules showed squamous differentiation.
+Sclerosis of stroma around the cords was present.
+Tumour cells were not connected to the epidermis.
+The immunohistochemical analysis showed positivity for anti-CK7 (Figure 4), AE1/AE3 and negativity for anti CEA and anti CK20.
+Based upon her histological and immunohistochemical presentation, the diagnosis of syringomatous eccrine carcinoma was established.
+Radiotherapy of the involved area was performed (70 Gy, 35 sessions)