Downloads: 1
250 lines (249 with data), 8.4 kB
T1 Age 2 13 51-year-old T2 Sex 14 17 man T3 Clinical_event 22 30 referred E1 Clinical_event:T3 T4 Biological_structure 38 46 hospital R1 MODIFY Arg1:T4 Arg2:E1 T5 Severity 54 60 severe T6 Disease_disorder 72 85 heart failure E2 Disease_disorder:T6 T7 Detailed_description 61 71 congestive R2 MODIFY Arg1:T7 Arg2:E2 R3 MODIFY Arg1:T5 Arg2:E2 T8 Disease_disorder 102 113 arrhythmias E3 Disease_disorder:T8 T9 Biological_structure 90 101 ventricular R4 MODIFY Arg1:T9 Arg2:E3 T10 Date 117 127 March 2008 E4 Date:T10 T11 Disease_disorder 156 169 heart failure E5 Disease_disorder:T11 T12 Sign_symptom 186 197 tachycardia E6 Sign_symptom:T12 T13 Biological_structure 174 185 ventricular R5 MODIFY Arg1:T13 Arg2:E6 T14 Duration 198 207 for years E7 Duration:T14 T15 Therapeutic_procedure 230 252 conventional treatment E8 Therapeutic_procedure:T15 T16 Medication 258 268 furosemide E9 Medication:T16 T17 Medication 270 288 lisinopril hydrate E10 Medication:T17 T18 Medication 290 300 pimobendan E11 Medication:T18 T19 Medication 302 320 warfarin potassium E12 Medication:T19 T20 Medication 322 332 carvedilol E13 Medication:T20 T21 Medication 334 346 metildigoxin E14 Medication:T21 T22 Medication 351 375 amiodarone hydrochloride E15 Medication:T22 R6 SUB_PROCEDURE Arg1:E9 Arg2:E8 R7 SUB_PROCEDURE Arg1:E10 Arg2:E8 R8 SUB_PROCEDURE Arg1:E11 Arg2:E8 R9 SUB_PROCEDURE Arg1:E12 Arg2:E8 R10 SUB_PROCEDURE Arg1:E13 Arg2:E8 R11 SUB_PROCEDURE Arg1:E14 Arg2:E8 R12 SUB_PROCEDURE Arg1:E15 Arg2:E8 T23 Height 393 399 161 cm T24 Weight 420 425 83 kg T25 Diagnostic_procedure 427 441 Blood pressure E16 Diagnostic_procedure:T25 T26 Lab_value 446 458 110/60 mm Hg R13 MODIFY Arg1:T26 Arg2:E16 T27 Diagnostic_procedure 464 485 fasting blood glucose E17 Diagnostic_procedure:T27 T28 Lab_value 490 499 107 mg/dl R14 MODIFY Arg1:T28 Arg2:E17 T29 Diagnostic_procedure 504 509 HbA1c E18 Diagnostic_procedure:T29 T30 Lab_value 514 518 6.3% R15 MODIFY Arg1:T30 Arg2:E18 T31 Diagnostic_procedure 530 535 x-ray E19 Diagnostic_procedure:T31 T32 Biological_structure 524 529 chest R16 MODIFY Arg1:T32 Arg2:E19 T33 Sign_symptom 543 555 cardiomegaly E20 Sign_symptom:T33 T34 Diagnostic_procedure 563 583 cardiothoracic ratio E21 Diagnostic_procedure:T34 T35 Lab_value 587 591 0.67 R17 MODIFY Arg1:T35 Arg2:E21 T36 Diagnostic_procedure 605 608 ECG E22 Diagnostic_procedure:T36 T37 Sign_symptom 651 677 hypokinetic left ventricle E23 Sign_symptom:T37 T38 Detailed_description 642 650 diffused R18 MODIFY Arg1:T38 Arg2:E23 T39 Diagnostic_procedure 700 724 left ventricle dimension E24 Diagnostic_procedure:T39 T41 Diagnostic_procedure 726 738 end-diastole E25 Diagnostic_procedure:T41 T42 Lab_value 740 745 95 mm R20 MODIFY Arg1:T42 Arg2:E25 T43 Diagnostic_procedure 759 761 EF E26 Diagnostic_procedure:T43 T44 Lab_value 763 767 0.11 R21 MODIFY Arg1:T44 Arg2:E26 #1 AnnotatorNotes E26 ejection fraction T45 Lab_value 751 758 reduced R22 MODIFY Arg1:T45 Arg2:E26 T46 Diagnostic_procedure 783 792 angiogram E27 Diagnostic_procedure:T46 T47 Biological_structure 774 782 coronary R23 MODIFY Arg1:T47 Arg2:E27 T48 Lab_value 797 803 normal R24 MODIFY Arg1:T48 Arg2:E27 T49 Diagnostic_procedure 818 824 biopsy E28 Diagnostic_procedure:T49 T50 Biological_structure 807 817 myocardial R25 MODIFY Arg1:T50 Arg2:E28 T51 Sign_symptom 1002 1021 thickening of hands E29 Sign_symptom:T51 T52 Nonbiological_location 1046 1070 endocrinology department T53 Clinical_event 1030 1038 referred E30 Clinical_event:T53 T54 Diagnostic_procedure 1076 1094 plasma level of GH E31 Diagnostic_procedure:T54 T55 Diagnostic_procedure 1113 1118 IGF-1 E32 Diagnostic_procedure:T55 T56 Lab_value 1099 1108 8.2 ng/ml R26 MODIFY Arg1:T56 Arg2:E31 T57 Lab_value 1123 1132 504 ng/ml R27 MODIFY Arg1:T57 Arg2:E32 T58 Diagnostic_procedure 1134 1137 MRI E33 Diagnostic_procedure:T58 T59 Disease_disorder 1153 1165 macroadenoma E34 Disease_disorder:T59 T60 Biological_structure 1173 1182 pituitary R28 MODIFY Arg1:T60 Arg2:E34 T61 Therapeutic_procedure 919 945 cardioverter-defibrillator E35 Therapeutic_procedure:T61 T62 Detailed_description 907 918 implantable R29 MODIFY Arg1:T62 Arg2:E35 T63 Sign_symptom 883 891 fibrosis E36 Sign_symptom:T63 T64 Lab_value 839 865 over 50% of cardiomyocytes R30 MODIFY Arg1:T64 Arg2:E36 T65 Diagnostic_procedure 980 997 facial appearance E37 Diagnostic_procedure:T65 T66 Lab_value 972 979 typical R31 MODIFY Arg1:T66 Arg2:E37 T67 Disease_disorder 1210 1220 acromegaly E38 Disease_disorder:T67 T68 Medication 1242 1252 octreotide E39 Medication:T68 T69 Duration 1283 1291 8 months E40 Duration:T69 T70 Detailed_description 1253 1272 long-acting-release T71 Detailed_description 1274 1277 LAR R32 IDENTICAL Arg1:T71 Arg2:T70 R33 MODIFY Arg1:T70 Arg2:E39 T72 Therapeutic_procedure 1318 1342 trans-sphenoidal surgery E41 Therapeutic_procedure:T72 T73 Date 1346 1358 January 2009 E42 Date:T73 T74 Medication 2066 2076 pimobendan E43 Medication:T74 T75 Diagnostic_procedure 1375 1394 plasma levels of GH E44 Diagnostic_procedure:T75 T76 Diagnostic_procedure 1399 1404 IGF-1 E45 Diagnostic_procedure:T76 T77 Lab_value 1410 1419 decreased R34 MODIFY Arg1:T77 Arg2:E45 R35 MODIFY Arg1:T77 Arg2:E44 T78 Medication 1425 1435 octreotide E46 Medication:T78 T79 Diagnostic_procedure 1445 1470 basal plasma levels of GH E47 Diagnostic_procedure:T79 T80 Lab_value 1483 1500 more than 4 ng/ml R36 MODIFY Arg1:T80 Arg2:E47 T81 Diagnostic_procedure 1505 1524 plasma IGF-1 levels E48 Diagnostic_procedure:T81 T82 Lab_value 1530 1561 above the appropriate age range R37 MODIFY Arg1:T82 Arg2:E48 T83 Coreference 1580 1587 surgery E49 Coreference:T83 R38 IDENTICAL Arg1:E49 Arg2:E41 T84 Diagnostic_procedure 1594 1613 plasma levels of GH E50 Diagnostic_procedure:T84 T85 Diagnostic_procedure 1618 1623 IGF-1 E51 Diagnostic_procedure:T85 T86 Lab_value 1624 1641 further decreased R39 MODIFY Arg1:T86 Arg2:E51 R40 MODIFY Arg1:T86 Arg2:E50 T87 Diagnostic_procedure 1643 1668 Basal plasma levels of GH E52 Diagnostic_procedure:T87 T88 Lab_value 1674 1700 mostly less than 0.5 ng/ml R41 MODIFY Arg1:T88 Arg2:E52 T89 Diagnostic_procedure 1705 1710 IGF-1 E53 Diagnostic_procedure:T89 T90 Lab_value 1723 1743 within normal ranges R42 MODIFY Arg1:T90 Arg2:E53 T91 Coreference 1778 1781 LAR E54 Coreference:T91 R43 IDENTICAL Arg1:E54 Arg2:E46 T92 Detailed_description 1436 1439 LAR R44 MODIFY Arg1:T92 Arg2:E46 T93 Diagnostic_procedure 1787 1803 cardiac function E55 Diagnostic_procedure:T93 T94 Lab_value 1804 1822 improved partially R45 MODIFY Arg1:T94 Arg2:E55 T95 Diagnostic_procedure 1824 1844 cardiothoracic ratio E56 Diagnostic_procedure:T95 T96 Lab_value 1845 1849 0.58 R46 MODIFY Arg1:T96 Arg2:E56 T97 Diagnostic_procedure 1851 1853 EF E57 Diagnostic_procedure:T97 T98 Lab_value 1854 1858 0.20 R47 MODIFY Arg1:T98 Arg2:E57 T99 Date 1862 1876 September 2008 E58 Date:T99 T100 Coreference 1885 1892 surgery E59 Coreference:T100 R48 IDENTICAL Arg1:E59 Arg2:E49 T101 Diagnostic_procedure 1898 1914 cardiac function E60 Diagnostic_procedure:T101 T102 Lab_value 1915 1935 improved drastically R49 MODIFY Arg1:T102 Arg2:E60 T103 Diagnostic_procedure 1937 1957 cardiothoracic ratio E61 Diagnostic_procedure:T103 T104 Lab_value 1958 1962 0.47 R50 MODIFY Arg1:T104 Arg2:E61 T105 Diagnostic_procedure 1964 1966 EF E62 Diagnostic_procedure:T105 T106 Lab_value 1967 1971 0.55 R51 MODIFY Arg1:T106 Arg2:E62 T107 Date 1975 1985 April 2009 E63 Date:T107 T108 Disease_disorder 2040 2051 arrhythmias E64 Disease_disorder:T108 T109 Biological_structure 2028 2039 ventricular R52 MODIFY Arg1:T109 Arg2:E64 T110 Lab_value 2015 2024;2052 2061 Frequency decreased A1 TREND E43 DEC * OVERLAP E1 E2 E3 E4 R53 AFTER Arg1:E4 Arg2:E5 * OVERLAP E5 E6 E7 E8 R54 BEFORE Arg1:E8 Arg2:E16 * OVERLAP E16 E17 E18 E19 E20 E21 E22 E23 E24 E25 E26 E27 E28 E36 T40 Lab_value 683 699 markedly dilated R19 MODIFY Arg1:T40 Arg2:E24 R55 BEFORE Arg1:E36 Arg2:E35 * OVERLAP E35 E37 E29 R56 BEFORE Arg1:E29 Arg2:E30 R57 MODIFY Arg1:T52 Arg2:E30 * OVERLAP E30 E31 E32 E33 E34 E38 R58 BEFORE Arg1:E38 Arg2:E39 * OVERLAP E39 E40 R59 BEFORE Arg1:E40 Arg2:E41 * OVERLAP E41 E42 R60 AFTER Arg1:E42 Arg2:E44 * OVERLAP E44 E45 E46 E47 E48 R61 BEFORE Arg1:E48 Arg2:E49 R62 BEFORE Arg1:E49 Arg2:E50 * OVERLAP E50 E51 E52 E53 E54 E55 E56 E57 E58 R63 BEFORE Arg1:E58 Arg2:E59 * OVERLAP E59 E60 E61 E62 E63 E64 E43