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T1 Age 2 13 52-year-old T2 Sex 14 17 man T3 Disease_disorder 60 82 dilated cardiomyopathy E1 Disease_disorder:T3 T4 Disease_disorder 84 87 DCM E2 Disease_disorder:T4 R1 IDENTICAL Arg1:E2 Arg2:E1 T5 Disease_disorder 117 130 heart failure E3 Disease_disorder:T5 A1 TREND E3 INC T6 Lab_value 132 145 NYHA class IV R2 MODIFY Arg1:T6 Arg2:E3 T7 History 19 44 body surface area: 1.3 m2 #1 AnnotatorNotes T7 This is a strange value to provide T8 Duration 168 175 5-month E4 Duration:T8 T9 Sign_symptom 187 192 cough E5 Sign_symptom:T9 T10 Sign_symptom 206 214 dyspnoea E6 Sign_symptom:T10 T11 Detailed_description 194 205 progressive R3 MODIFY Arg1:T11 Arg2:E6 T12 Sign_symptom 216 225 orthopnea E7 Sign_symptom:T12 T13 Sign_symptom 256 260 pain E8 Sign_symptom:T13 T14 Biological_structure 240 255 upper abdominal T15 Detailed_description 230 239 recurrent R4 MODIFY Arg1:T14 Arg2:E8 R5 MODIFY Arg1:T15 Arg2:E8 T16 Duration 269 286 from 2 months ago E9 Duration:T16 T17 Diagnostic_procedure 291 302 examination E10 Diagnostic_procedure:T17 T18 Diagnostic_procedure 307 318 vital signs E11 Diagnostic_procedure:T18 R6 SUB_PROCEDURE Arg1:E11 Arg2:E10 T19 Diagnostic_procedure 324 340 body temperature E12 Diagnostic_procedure:T19 T20 Lab_value 341 345 37°C R7 MODIFY Arg1:T20 Arg2:E12 T21 Diagnostic_procedure 347 361 blood pressure E13 Diagnostic_procedure:T21 T22 Lab_value 362 372 80/40 mmHg R8 MODIFY Arg1:T22 Arg2:E13 T23 Diagnostic_procedure 374 390 respiratory rate E14 Diagnostic_procedure:T23 T24 Lab_value 391 412 24 breaths per minute R9 MODIFY Arg1:T24 Arg2:E14 T25 Diagnostic_procedure 418 435 electrocardiogram E15 Diagnostic_procedure:T25 T26 Disease_disorder 443 462 atrial fibrillation E16 Disease_disorder:T26 T27 Diagnostic_procedure 468 478 heart rate E17 Diagnostic_procedure:T27 T28 Lab_value 479 498 50 beats per minute R10 MODIFY Arg1:T28 Arg2:E17 R11 SUB_PROCEDURE Arg1:E12 Arg2:E11 R12 SUB_PROCEDURE Arg1:E13 Arg2:E11 R13 SUB_PROCEDURE Arg1:E14 Arg2:E11 T29 Diagnostic_procedure 500 520 Physical examination E18 Diagnostic_procedure:T29 T30 Sign_symptom 549 559 distension E19 Sign_symptom:T30 T31 Biological_structure 534 548 jugular venous R14 MODIFY Arg1:T31 Arg2:E19 T32 Sign_symptom 580 592 hepatomegaly E20 Sign_symptom:T32 T33 Detailed_description 573 579 tender R15 MODIFY Arg1:T33 Arg2:E20 T34 Severity 561 572 significant R16 MODIFY Arg1:T34 Arg2:E20 T35 Sign_symptom 615 620 edema E21 Sign_symptom:T35 T36 Detailed_description 607 614 pitting T37 Detailed_description 597 606 bilateral R17 MODIFY Arg1:T36 Arg2:E21 R18 MODIFY Arg1:T37 Arg2:E21 T38 Biological_structure 624 635 lower limbs R19 MODIFY Arg1:T38 Arg2:E21 T39 Diagnostic_procedure 637 653 Laboratory tests E22 Diagnostic_procedure:T39 T40 Diagnostic_procedure 670 702 pro-NT brain natriuretic peptide E23 Diagnostic_procedure:T40 T41 Lab_value 661 669 elevated R20 MODIFY Arg1:T41 Arg2:E23 T42 Lab_value 706 717 22145 pg/ml R21 MODIFY Arg1:T42 Arg2:E23 T43 Diagnostic_procedure 759 766 D-dimer E24 Diagnostic_procedure:T43 T44 Lab_value 746 758 unremarkable R22 MODIFY Arg1:T44 Arg2:E24 T45 Diagnostic_procedure 768 773 X-ray E25 Diagnostic_procedure:T45 T46 Diagnostic_procedure 778 797 computed tomography E26 Diagnostic_procedure:T46 T47 Biological_structure 805 810 chest R23 MODIFY Arg1:T47 Arg2:E26 R24 MODIFY Arg1:T47 Arg2:E25 T48 Sign_symptom 868 884 pleural effusion E27 Sign_symptom:T48 T49 Sign_symptom 824 837 consolidation E28 Sign_symptom:T49 T50 Biological_structure 841 862 bilateral lower lobes R25 MODIFY Arg1:T50 Arg2:E28 T51 Diagnostic_procedure 903 910 Doppler E29 Diagnostic_procedure:T51 T52 Biological_structure 896 902 venous R26 MODIFY Arg1:T52 Arg2:E29 T53 Biological_structure 914 931 lower extremities R27 MODIFY Arg1:T53 Arg2:E29 T54 Lab_value 936 942 normal R28 MODIFY Arg1:T54 Arg2:E29 T55 Diagnostic_procedure 977 993 echocardiography E30 Diagnostic_procedure:T55 T56 Sign_symptom 1038 1062 dilated cardiac chambers E31 Sign_symptom:T56 T57 Severity 1031 1037 severe R29 MODIFY Arg1:T57 Arg2:E31 T58 Sign_symptom 1075 1086 enlargement E32 Sign_symptom:T58 T59 Biological_structure 1094 1108 left ventricle T60 Biological_structure 1110 1112 LV R30 IDENTICAL Arg1:T60 Arg2:T59 R31 MODIFY Arg1:T59 Arg2:E32 T61 Lab_value 1115 1123 58 mm/m2 R32 MODIFY Arg1:T61 Arg2:E32 T63 Sign_symptom 1147 1171 decreased wall thickness E33 Sign_symptom:T63 T64 Diagnostic_procedure 1182 1199 ejection fraction E34 Diagnostic_procedure:T64 T65 Lab_value 1173 1181 impaired R34 MODIFY Arg1:T65 Arg2:E34 T66 Lab_value 1200 1203 22% R35 MODIFY Arg1:T66 Arg2:E34 T67 Diagnostic_procedure 1239 1285 two-dimensional transthoracic echocardiography E35 Diagnostic_procedure:T67 T68 Diagnostic_procedure 1287 1292 2DTTE E36 Diagnostic_procedure:T68 R36 IDENTICAL Arg1:E36 Arg2:E35 T69 Sign_symptom 1215 1235 mitral regurgitation E37 Sign_symptom:T69 T70 Severity 1208 1214 severe R37 MODIFY Arg1:T70 Arg2:E37 T62 Sign_symptom 1130 1145 spherical shape E38 Sign_symptom:T62 #2 AnnotatorNotes E38 Specifically, spherical shape of the heart T71 Sign_symptom 1381 1385 mass E39 Sign_symptom:T71 T72 Disease_disorder 1409 1417 thrombus E40 Disease_disorder:T72 A2 POLARITY E40 MAYBE_POS T73 Biological_structure 1433 1452 right atrial cavity R33 MODIFY Arg1:T73 Arg2:E40 T74 Disease_disorder 1529 1536 thrombi E41 Disease_disorder:T74 T75 Diagnostic_procedure 1538 1596 Real-time three dimensional transthoracic echocardiography E42 Diagnostic_procedure:T75 T76 Diagnostic_procedure 1598 1606 RT-3DTTE E43 Diagnostic_procedure:T76 R38 IDENTICAL Arg1:E43 Arg2:E42 T77 Sign_symptom 1655 1659 mass E44 Sign_symptom:T77 T78 Biological_structure 1368 1380 right atrial R39 MODIFY Arg1:T78 Arg2:E39 T79 Detailed_description 1361 1367 mobile R40 MODIFY Arg1:T79 Arg2:E39 T80 Detailed_description 1496 1509 free-floating T81 Detailed_description 1510 1521 small parts R41 MODIFY Arg1:T81 Arg2:E41 R42 MODIFY Arg1:T80 Arg2:E41 T82 Disease_disorder 1687 1695 thrombus E45 Disease_disorder:T82 T83 Detailed_description 1673 1686 highly mobile R43 MODIFY Arg1:T83 Arg2:E45 T84 Shape 1697 1717 irregular in contour R44 MODIFY Arg1:T84 Arg2:E45 T85 Area 1728 1740 2.6 × 1.0 cm R45 MODIFY Arg1:T85 Arg2:E45 T86 Biological_structure 1767 1796 orifice of inferior vena cava R46 MODIFY Arg1:T86 Arg2:E45 T87 Coreference 1661 1663 It E46 Coreference:T87 R47 IDENTICAL Arg1:E46 Arg2:E42 T88 Biological_structure 1801 1840 protruding into the right atrial cavity R48 MODIFY Arg1:T88 Arg2:E45 T89 Diagnostic_procedure 1867 1875 RT-3DTTE E47 Diagnostic_procedure:T89 T90 Biological_structure 1886 1901 right ventricle T91 Biological_structure 1903 1905 RV R49 IDENTICAL Arg1:T91 Arg2:T90 R50 MODIFY Arg1:T90 Arg2:E47 T92 Sign_symptom 1907 1927 systolic dysfunction E48 Sign_symptom:T92 T93 Diagnostic_procedure 1933 1950 ejection fraction E49 Diagnostic_procedure:T93 T94 Lab_value 1951 1956 15.7% R51 MODIFY Arg1:T94 Arg2:E49 T95 Medication 1991 1998 digoxin E50 Medication:T95 T96 Medication 2000 2014 spironolactone E51 Medication:T96 T97 Medication 2016 2026 furosemide E52 Medication:T97 T98 Medication 2028 2035 sotalol E53 Medication:T98 T99 Medication 2040 2048 dopamine E54 Medication:T99 T100 Therapeutic_procedure 2067 2094 therapeutic anticoagulation E55 Therapeutic_procedure:T100 T101 Medication 2133 2140 heparin E56 Medication:T101 T102 Medication 2145 2153 warfarin E57 Medication:T102 T103 Detailed_description 2112 2132 low-molecular-weight R52 MODIFY Arg1:T103 Arg2:E56 R53 SUB_PROCEDURE Arg1:E56 Arg2:E55 R54 SUB_PROCEDURE Arg1:E57 Arg2:E55 T104 Therapeutic_procedure 2185 2200 hospital course E58 Therapeutic_procedure:T104 T105 Lab_value 2174 2184 uneventful R55 MODIFY Arg1:T105 Arg2:E58 T106 Date 2205 2213 one week E59 Date:T106 T107 Clinical_event 2214 2223 follow-up E60 Clinical_event:T107 T108 Diagnostic_procedure 2224 2240 echocardiography E61 Diagnostic_procedure:T108 T109 Disease_disorder 2275 2283 thrombus E62 Disease_disorder:T109 A3 POLARITY E62 NEG T110 Clinical_event 94 102 admitted E63 Clinical_event:T110 T111 History 60 82 dilated cardiomyopathy R56 BEFORE Arg1:E1 Arg2:E63 * OVERLAP E63 E3 R57 AFTER Arg1:E3 Arg2:E4 * OVERLAP E4 E5 E6 E7 R58 BEFORE Arg1:E7 Arg2:E8 * OVERLAP E8 E9 R59 BEFORE Arg1:E9 Arg2:E10 * OVERLAP E10 E15 E16 E17 E18 E19 E20 E21 E22 E23 E24 E25 E26 E28 E27 E29 E30 E31 E32 E38 E33 E34 E37 E35 E39 E40 E41 E42 E44 E46 E45 E47 E48 E49 R60 BEFORE Arg1:E49 Arg2:E50 * OVERLAP E50 E51 E52 E53 E54 E55 R61 BEFORE Arg1:E55 Arg2:E58 R62 BEFORE Arg1:E58 Arg2:E59 * OVERLAP E59 E60 E61 E62