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T1 Age 2 13 48 year-old T2 Sex 14 20 female T3 Sign_symptom 44 52 bleeding E1 Sign_symptom:T3 T4 Biological_structure 36 43 vaginal R1 MODIFY Arg1:T4 Arg2:E1 T5 Diagnostic_procedure 66 76 Pap smears E2 Diagnostic_procedure:T5 T6 Lab_value 57 65 abnormal R2 MODIFY Arg1:T6 Arg2:E2 T7 Disease_disorder 122 125 SCC E3 Disease_disorder:T7 #1 AnnotatorNotes E3 Squamous cell carcinoma T8 Biological_structure 133 139 cervix R3 MODIFY Arg1:T8 Arg2:E3 T9 Detailed_description 105 121 non-keratinizing R4 MODIFY Arg1:T9 Arg2:E3 T10 Detailed_description 96 104 invasive R5 MODIFY Arg1:T10 Arg2:E3 T11 Therapeutic_procedure 165 177 hysterectomy E4 Therapeutic_procedure:T11 T12 Detailed_description 157 164 radical R6 MODIFY Arg1:T12 Arg2:E4 T13 Therapeutic_procedure 183 204 salpingo-oophorectomy E5 Therapeutic_procedure:T13 R7 SUB_PROCEDURE Arg1:E5 Arg2:E4 T14 Biological_structure 247 265 pelvic lymph nodes T15 Biological_structure 274 285 parametrium T16 Sign_symptom 224 239 positive spread E6 Sign_symptom:T16 R8 MODIFY Arg1:T14 Arg2:E6 R9 MODIFY Arg1:T15 Arg2:E6 T17 Biological_structure 367 388 lower uterine segment T18 Coreference 330 336 tumour E7 Coreference:T18 R10 IDENTICAL Arg1:E7 Arg2:E3 T19 Diagnostic_procedure 287 311 Pathological examination E8 Diagnostic_procedure:T19 T20 Date 390 417 5 months after this surgery E9 Date:T20 T21 Therapeutic_procedure 453 465 radiotherapy E10 Therapeutic_procedure:T21 T22 Detailed_description 439 452 external beam R11 MODIFY Arg1:T22 Arg2:E10 T23 Therapeutic_procedure 484 497 brachytherapy E11 Therapeutic_procedure:T23 T24 Detailed_description 470 483 intracavitary R12 MODIFY Arg1:T24 Arg2:E11 T25 Date 499 514 Two years later E12 Date:T25 T26 Duration 545 556 three-month E13 Duration:T26 T27 Sign_symptom 581 586 cough E14 Sign_symptom:T27 T28 Detailed_description 570 580 productive R13 MODIFY Arg1:T28 Arg2:E14 T29 Sign_symptom 588 607 shortness of breath E15 Sign_symptom:T29 T30 Duration 615 623 2-3 week E16 Duration:T30 T31 Sign_symptom 658 665 dyspnea E17 Sign_symptom:T31 T32 Detailed_description 647 657 exertional R14 MODIFY Arg1:T32 Arg2:E17 T33 Detailed_description 635 646 progressive R15 MODIFY Arg1:T33 Arg2:E17 T34 Diagnostic_procedure 667 673 X-rays E18 Diagnostic_procedure:T34 T35 Biological_structure 681 686 chest R16 MODIFY Arg1:T35 Arg2:E18 T36 Diagnostic_procedure 733 741 CT scans E19 Diagnostic_procedure:T36 T37 Diagnostic_procedure 989 1001 bronchoscopy E20 Diagnostic_procedure:T37 T38 Diagnostic_procedure 1008 1020 thoracoscopy E21 Diagnostic_procedure:T38 T39 Detailed_description 1003 1007 left R17 MODIFY Arg1:T39 Arg2:E21 T40 Diagnostic_procedure 1050 1056 biopsy E22 Diagnostic_procedure:T40 T41 Biological_structure 1040 1049 left lung R18 MODIFY Arg1:T41 Arg2:E22 T42 Detailed_description 1029 1039 open wedge R19 MODIFY Arg1:T42 Arg2:E22 T43 Diagnostic_procedure 1058 1082 Pathological examination E23 Diagnostic_procedure:T43 T44 Disease_disorder 1708 1735 lymphangitic carcinomatosis E24 Disease_disorder:T44 T45 Biological_structure 1743 1747 lung R20 MODIFY Arg1:T45 Arg2:E24 T46 Medication 1822 1827 Taxol E25 Medication:T46 T47 Medication 1816 1821 Carbo E26 Medication:T47 T48 Medication 1834 1849 corticosteroids E27 Medication:T48 T49 Clinical_event 1881 1891 discharged E28 Clinical_event:T49 T50 Coreference 1100 1106 biopsy E29 Coreference:T50 R21 IDENTICAL Arg1:E29 Arg2:E22 T51 Biological_structure 1090 1099 left lung R22 MODIFY Arg1:T51 Arg2:E29 R23 MODIFY Arg1:E29 Arg2:E23 T52 Biological_structure 1184 1208 along the septal vessels T53 Biological_structure 1210 1222 perivascular T54 Biological_structure 1224 1237 peribronchial T55 Biological_structure 1254 1264 lymphatics T56 Biological_structure 1243 1253 subpleural R24 MODIFY Arg1:T56 Arg2:T55 R25 MODIFY Arg1:T54 Arg2:T55 R26 MODIFY Arg1:T53 Arg2:T55 T57 Sign_symptom 1133 1159 neoplastic sheets of cells E30 Sign_symptom:T57 R27 MODIFY Arg1:T55 Arg2:E30 R28 MODIFY Arg1:T52 Arg2:E30 T58 Diagnostic_procedure 1974 1994 radiographic imaging E31 Diagnostic_procedure:T58 T59 Outcome 2172 2176 died E32 Outcome:T59 T60 Date 2177 2214 13 months after the initial diagnosis E33 Date:T60 T61 Disease_disorder 927 936 pneumonia E34 Disease_disorder:T61 T62 Detailed_description 914 926 interstitial R29 MODIFY Arg1:T62 Arg2:E34 T63 Sign_symptom 960 965 edema E35 Sign_symptom:T63 T64 Detailed_description 944 959 non-cardiogenic R30 MODIFY Arg1:T64 Arg2:E35 A1 POLARITY E34 UNCERTAIN A2 POLARITY E35 UNCERTAIN T65 Detailed_description 760 782 bilateral patchy areas T66 Texture 786 806 ground glass opacity T67 Sign_symptom 807 815 scarring E36 Sign_symptom:T67 R31 MODIFY Arg1:T66 Arg2:E36 R32 MODIFY Arg1:T65 Arg2:E36 T68 Sign_symptom 849 860 atelectasis E37 Sign_symptom:T68 T69 Detailed_description 836 848 subsegmental R33 MODIFY Arg1:T69 Arg2:E37 T70 Biological_structure 868 878 both lungs R34 MODIFY Arg1:T70 Arg2:E37 T71 Coreference 1327 1343 neoplastic cells E38 Coreference:T71 R35 IDENTICAL Arg1:E38 Arg2:E30 T72 Sign_symptom 1277 1284 nodules E39 Sign_symptom:T72 T73 Biological_structure 1266 1276 Subpleural R36 MODIFY Arg1:T73 Arg2:E39 T74 Disease_disorder 1392 1394 LC E40 Disease_disorder:T74 #2 AnnotatorNotes E40 Lung cancer, or lymphangitic carcinomatosis T75 Biological_structure 1359 1380 subpleural lymphatics R37 MODIFY Arg1:T75 Arg2:E38 T76 Diagnostic_procedure 1420 1448 immunohistochemical analysis E41 Diagnostic_procedure:T76 T77 Diagnostic_procedure 1495 1498 p16 E42 Diagnostic_procedure:T77 T78 Diagnostic_procedure 1512 1550 high and low molecular weight keratins E43 Diagnostic_procedure:T78 T79 Diagnostic_procedure 1564 1577 cytokeratin-7 E44 Diagnostic_procedure:T79 T80 Diagnostic_procedure 1597 1601 CK19 E45 Diagnostic_procedure:T80 T81 Diagnostic_procedure 1607 1618 pan keratin E46 Diagnostic_procedure:T81 T82 Diagnostic_procedure 1636 1640 CK20 E47 Diagnostic_procedure:T82 T83 Diagnostic_procedure 1642 1645 p63 E48 Diagnostic_procedure:T83 T84 Diagnostic_procedure 1651 1655 EGFR E49 Diagnostic_procedure:T84 R38 SUB_PROCEDURE Arg1:E42 Arg2:E41 R39 SUB_PROCEDURE Arg1:E43 Arg2:E41 R40 SUB_PROCEDURE Arg1:E44 Arg2:E41 R41 SUB_PROCEDURE Arg1:E45 Arg2:E41 R42 SUB_PROCEDURE Arg1:E46 Arg2:E41 R43 SUB_PROCEDURE Arg1:E47 Arg2:E41 R44 SUB_PROCEDURE Arg1:E48 Arg2:E41 R45 SUB_PROCEDURE Arg1:E49 Arg2:E41 T85 Lab_value 1483 1491 positive R46 MODIFY Arg1:T85 Arg2:E42 R47 MODIFY Arg1:T85 Arg2:E43 R48 MODIFY Arg1:T85 Arg2:E44 R49 MODIFY Arg1:T85 Arg2:E45 R50 MODIFY Arg1:T85 Arg2:E46 T86 Lab_value 1624 1632 negative R51 MODIFY Arg1:T86 Arg2:E47 R52 MODIFY Arg1:T86 Arg2:E48 R53 MODIFY Arg1:T86 Arg2:E49 T87 Sign_symptom 1748 1758 metastatic E50 Sign_symptom:T87 T88 Disease_disorder 1764 1767 SCC E51 Disease_disorder:T88 T89 Biological_structure 1775 1781 cervix R54 MODIFY Arg1:T89 Arg2:E51 R55 MODIFY Arg1:E50 Arg2:E24 R56 MODIFY Arg1:E51 Arg2:E50 T90 Sign_symptom 2073 2096 interstitial thickening E52 Sign_symptom:T90 T91 Sign_symptom 2042 2064 nodular opacifications E53 Sign_symptom:T91 T92 Lab_value 2023 2034 improvement R57 MODIFY Arg1:T92 Arg2:E53 R58 MODIFY Arg1:T92 Arg2:E52 T93 Sign_symptom 1938 1955 clinical symptoms E54 Sign_symptom:T93 T94 Lab_value 1923 1934 improvement R59 MODIFY Arg1:T94 Arg2:E54 * OVERLAP E1 E2 E57 R60 AFTER Arg1:E2 Arg2:E3 * OVERLAP E3 E4 E6 E8 R61 MODIFY Arg1:T17 Arg2:E8 R62 BEFORE Arg1:E8 Arg2:E9 * OVERLAP E9 E10 E11 R63 BEFORE Arg1:E11 Arg2:E12 R64 MODIFY Arg1:E13 Arg2:E14 * OVERLAP E12 E14 E15 E17 R65 MODIFY Arg1:E16 Arg2:E17 R66 BEFORE Arg1:E17 Arg2:E18 * OVERLAP E18 E19 E36 E37 E34 E35 R67 BEFORE Arg1:E35 Arg2:E20 * OVERLAP E20 E21 E22 E23 E30 E39 E40 E41 E24 E50 E51 T95 Medication 1802 1814 chemotherapy E55 Medication:T95 R69 SUB_PROCEDURE Arg1:E26 Arg2:E55 R70 SUB_PROCEDURE Arg1:E25 Arg2:E55 R68 BEFORE Arg1:E51 Arg2:E55 * OVERLAP E55 E27 R71 BEFORE Arg1:E27 Arg2:E28 T96 Date 1892 1906 ten days later E56 Date:T96 * OVERLAP E28 E56 R72 BEFORE Arg1:E56 Arg2:E54 * OVERLAP E54 E31 E53 E52 R73 BEFORE Arg1:E52 Arg2:E32 * OVERLAP E32 E33 T97 Clinical_event 21 30 presented E57 Clinical_event:T97