T1  Age 2 13    21-year-old

T2  Sex 14 18   male

T3  Clinical_event 19 28    presented

E1  Clinical_event:T3 

T4  Duration 36 42  2-year

E2  Duration:T4 

T5  Sign_symptom 66 85  shortness of breath

E3  Sign_symptom:T5 

T6  Detailed_description 54 65  progressive

R1  MODIFY Arg1:T6 Arg2:E3  

T7  Detailed_description 89 97  exertion

R2  MODIFY Arg1:T7 Arg2:E3  

T8  Sign_symptom 102 111    dry cough

E4  Sign_symptom:T8 

T9  Diagnostic_procedure 116 136    physical examination

E5  Diagnostic_procedure:T9 

T10 Diagnostic_procedure 138 150    auscultation

E6  Diagnostic_procedure:T10 

T11 Biological_structure 158 163    lungs

R3  MODIFY Arg1:T11 Arg2:E6 

T12 Sign_symptom 184 191    wheezes

E7  Sign_symptom:T12 

T13 Detailed_description 177 183    random

R4  MODIFY Arg1:T13 Arg2:E7 

T14 Sign_symptom 196 211    coarse crackles

E8  Sign_symptom:T14 

T15 Biological_structure 213 220    Cardiac

T16 Diagnostic_procedure 221 233    auscultation

E9  Diagnostic_procedure:T16 

R5  MODIFY Arg1:T15 Arg2:E9 

T17 Sign_symptom 253 261    cyanosis

E10 Sign_symptom:T17 

A1  POLARITY E10 NEG

T18 Sign_symptom 265 281    peripheral edema

E11 Sign_symptom:T18 

A2  POLARITY E11 NEG

T19 History 306 327 no history of smoking

T20 Disease_disorder 346 363    pulmonary disease

E12 Disease_disorder:T20 

A3  POLARITY E12 NEG

T21 Diagnostic_procedure 376 393    blood examination

E13 Diagnostic_procedure:T21 

T22 Detailed_description 368 375    routine

R6  MODIFY Arg1:T22 Arg2:E13    

T23 Diagnostic_procedure 395 407    blood counts

E14 Diagnostic_procedure:T23 

T24 Diagnostic_procedure 412 429    serum chemistries

E15 Diagnostic_procedure:T24 

T25 Lab_value 447 453   normal

R7  MODIFY Arg1:T25 Arg2:E15    

R8  MODIFY Arg1:T25 Arg2:E14    

T26 Diagnostic_procedure 455 482    Arterial blood gas analysis

E16 Diagnostic_procedure:T26 

T27 Diagnostic_procedure 487 503    echocardiography

E17 Diagnostic_procedure:T27 

T28 Diagnostic_procedure 539 563    Pulmonary function tests

E18 Diagnostic_procedure:T28 

T29 Diagnostic_procedure 565 568    PFT

E19 Diagnostic_procedure:T29 

T30 Severity 579 583    mild

T31 Sign_symptom 584 614    restrictive ventilatory defect

E20 Sign_symptom:T31 

R9  MODIFY Arg1:T30 Arg2:E20    

T32 Diagnostic_procedure 631 650    total lung capacity

E21 Diagnostic_procedure:T32 

T33 Lab_value 623 630   reduced

R10 MODIFY Arg1:T33 Arg2:E21    

T34 Lab_value 654 657   79%

R11 MODIFY Arg1:T34 Arg2:E21    

T35 Lab_value 659 665   5.94 L

R12 MODIFY Arg1:T35 Arg2:E21    

T36 Diagnostic_procedure 668 689    forced vital capacity

E22 Diagnostic_procedure:T36 

T37 Lab_value 693 696   80%

R13 MODIFY Arg1:T37 Arg2:E22    

T38 Lab_value 698 704   4.18 L

R14 MODIFY Arg1:T38 Arg2:E22    

T39 Diagnostic_procedure 712 750    forced expiratory volume in one second

E23 Diagnostic_procedure:T39 

T40 Lab_value 754 757   83%

T41 Lab_value 759 765   3.72 L

T42 Diagnostic_procedure 796 827    acid-alcohol resistant bacillus

E24 Diagnostic_procedure:T42 

T43 Lab_value 783 791   negative

T44 Biological_structure 772 778    sputum

R15 MODIFY Arg1:T43 Arg2:E24    

R16 MODIFY Arg1:T44 Arg2:E24    

T45 Diagnostic_procedure 832 868    human immunodeficiency virus testing

E25 Diagnostic_procedure:T45 

T46 Lab_value 873 881   negative

R17 MODIFY Arg1:T46 Arg2:E25    

T47 Diagnostic_procedure 895 912    chest plain films

E26 Diagnostic_procedure:T47 

T48 Sign_symptom 958 978    micronodular pattern

E27 Sign_symptom:T48 

T49 Detailed_description 924 931    diffuse

T50 Detailed_description 932 941    symmetric

T51 Texture 942 947 dense

T52 Biological_structure 948 957    bilateral

R18 MODIFY Arg1:T52 Arg2:E27    

R19 MODIFY Arg1:T51 Arg2:E27    

R20 MODIFY Arg1:T50 Arg2:E27    

R21 MODIFY Arg1:T49 Arg2:E27    

T53 Diagnostic_procedure 1014 1023  HRCT scan

E28 Diagnostic_procedure:T53 

T54 Sign_symptom 1085 1102  septal thickening

E29 Sign_symptom:T54 

T55 Sign_symptom 1230 1235  cysts

E30 Sign_symptom:T55 

T56 Biological_structure 1219 1229  Subpleural

R22 MODIFY Arg1:T56 Arg2:E30    

T57 Diagnostic_procedure 1290 1313  fiberoptic bronchoscopy

E31 Diagnostic_procedure:T57 

T58 Diagnostic_procedure 1319 1341  bronchoalveolar lavage

E32 Diagnostic_procedure:T58 

T59 Diagnostic_procedure 1366 1372  biopsy

E33 Diagnostic_procedure:T59 

T60 Biological_structure 1346 1360  transbronchial

T61 Biological_structure 1361 1365  lung

R23 MODIFY Arg1:T61 Arg2:E33    

R24 MODIFY Arg1:T60 Arg2:E33    

T62 Diagnostic_procedure 1408 1420  tuberculosis

E34 Diagnostic_procedure:T62 

T63 Diagnostic_procedure 1424 1429  fungi

E35 Diagnostic_procedure:T63 

T64 Biological_structure 1378 1390  lavage fluid

T65 Lab_value 1395 1403 negative

R25 MODIFY Arg1:T65 Arg2:E34    

R26 MODIFY Arg1:T65 Arg2:E35    

R27 MODIFY Arg1:T64 Arg2:E34    

R28 MODIFY Arg1:T64 Arg2:E35    

T66 Sign_symptom 1431 1441  Microliths

E36 Sign_symptom:T66 

A4  POLARITY E36 NEG

T67 Diagnostic_procedure 1458 1467  Histology

E37 Diagnostic_procedure:T67 

T68 Sign_symptom 1509 1519  microliths

E38 Sign_symptom:T68 

T69 Shape 1477 1482 round

T70 Detailed_description 1484 1508  concentrically laminated

T71 Biological_structure 1527 1534  alveoli

R29 MODIFY Arg1:T70 Arg2:E38    

R30 MODIFY Arg1:T69 Arg2:E38    

T72 Disease_disorder 1623 1626  PAM

E39 Disease_disorder:T72 

R31 MODIFY Arg1:T71 Arg2:E38    

T73 Severity 1551 1559  slightly

T74 Sign_symptom 1560 1588  thickened interstitial septa

E40 Sign_symptom:T74 

R32 MODIFY Arg1:T73 Arg2:E40    

T75 Sign_symptom 1056 1080  ground glass attenuation

E41 Sign_symptom:T75 

T76 Biological_structure 1123 1146  lower pulmonary regions

R33 MODIFY Arg1:T76 Arg2:E29    

R34 MODIFY Arg1:T76 Arg2:E41    

T77 Sign_symptom 1153 1167  calcifications

E42 Sign_symptom:T77 

T78 Biological_structure 1178 1194  interlobar septa

T79 Biological_structure 1199 1217  subpleural regions

R35 MODIFY Arg1:T78 Arg2:E42    

R36 MODIFY Arg1:T79 Arg2:E42    

R37 MODIFY Arg1:E2 Arg2:E3  

*   OVERLAP E1 E3 E4

R38 BEFORE Arg1:E4 Arg2:E5  

R39 SUB_PROCEDURE Arg1:E6 Arg2:E5   

*   OVERLAP E5 E7 E8 E9 E10 E11

R40 AFTER Arg1:E11 Arg2:E12 

R41 BEFORE Arg1:E12 Arg2:E13    

*   OVERLAP E13 E14 E15 E16 E17 E18 E20

T80 Lab_value 511 537   no important abnormalities

R42 MODIFY Arg1:T80 Arg2:E17    

R43 MODIFY Arg1:T80 Arg2:E16    

R44 IDENTICAL Arg1:E19 Arg2:E18 

R45 SUB_PROCEDURE Arg1:E21 Arg2:E18 

R46 SUB_PROCEDURE Arg1:E22 Arg2:E18 

R47 SUB_PROCEDURE Arg1:E23 Arg2:E18 

R48 MODIFY Arg1:T40 Arg2:E23    

R49 MODIFY Arg1:T41 Arg2:E23    

*   OVERLAP E23 E24 E25 E26 E27

R50 BEFORE Arg1:E27 Arg2:E28    

*   OVERLAP E28 E41 E29 E42 E30

R51 BEFORE Arg1:E30 Arg2:E31    

*   OVERLAP E31 E32 E33 E34 E35 E36 E37 E38 E40 E39