270 lines (269 with data), 9.0 kB

T1	Age 36 47	60-year-old
T2	Sex 48 51	man
T3	Personal_background 57 70	San Francisco
T5	Activity 103 112	traveling
E1	Activity:T5 
T6	Nonbiological_location 120 131	Philippines
R1	MODIFY Arg1:T6 Arg2:E1	
T7	Activity 79 96	consumed raw pork
E2	Activity:T7 
T8	Date 136 145	June 2003
E3	Date:T8 
T9	Sign_symptom 163 166	ill
E4	Sign_symptom:T9 
T10	Sign_symptom 172 177	fever
E5	Sign_symptom:T10 
T11	Sign_symptom 179 190	diaphoresis
E6	Sign_symptom:T11 
T12	Sign_symptom 192 200	headache
E7	Sign_symptom:T12 
T13	Sign_symptom 202 208	nausea
E8	Sign_symptom:T13 
T14	Sign_symptom 214 222	anorexia
E9	Sign_symptom:T14 
T15	Duration 252 259	7-month
E10	Duration:T15 
T16	Activity 236 244	returned
E11	Activity:T16 
T18	Nonbiological_location 276 287	Philippines
T19	Date 289 320	Three days after symptoms onset
E12	Date:T19 
T20	Medication 347 358	doxycycline
E13	Medication:T20 
T22	Clinical_event 390 398	admitted
E14	Clinical_event:T22 
T23	Nonbiological_location 404 418	local hospital
T24	Date 419 431	5 days later
E15	Date:T24 
T25	Lab_value 448 454	38.9°C
T26	Sign_symptom 439 444	fever
E16	Sign_symptom:T26 
R3	MODIFY Arg1:T25 Arg2:E16	
T27	Sign_symptom 456 471	nuchal rigidity
E17	Sign_symptom:T27 
T28	Sign_symptom 473 481	headache
E18	Sign_symptom:T28 
T29	Sign_symptom 495 502	malaise
E19	Sign_symptom:T29 
T30	History 563 600	past medical history was unremarkable
T31	History 526 561	no recent contact with sick persons
T32	Diagnostic_procedure 605 625	physical examination
E20	Diagnostic_procedure:T32 
T33	Sign_symptom 634 643	somnolent
E21	Sign_symptom:T33 
T34	Sign_symptom 648 662	fully oriented
E22	Sign_symptom:T34 
T35	Diagnostic_procedure 690 712	neurologic examination
E23	Diagnostic_procedure:T35 
T36	Sign_symptom 672 686	focal findings
E24	Sign_symptom:T36 
A1	POLARITY E24 NEG
R4	MODIFY Arg1:E24 Arg2:E23	
T37	Sign_symptom 729 744	nuchal rigidity
E25	Sign_symptom:T37 
T38	Severity 722 728	slight
R5	MODIFY Arg1:T38 Arg2:E25	
T39	Diagnostic_procedure 755 770	leukocyte count
E26	Diagnostic_procedure:T39 
T40	Lab_value 774 784	21,000/mm3
T41	Diagnostic_procedure 807 818	neutrophils
E27	Diagnostic_procedure:T41 
T42	Lab_value 796 806	16,400/mm3
T43	Biological_structure 820 839	Cerebrospinal fluid
T44	Biological_structure 841 844	CSF
T45	Diagnostic_procedure 853 868	leukocyte count
E28	Diagnostic_procedure:T45 
T46	Lab_value 872 878	487/μL
T47	Lab_value 884 911	80% polymorphonuclear cells
T48	Lab_value 916 931	18% lymphocytes
T49	Diagnostic_procedure 937 944	glucose
E29	Diagnostic_procedure:T49 
T50	Diagnostic_procedure 949 956	protein
E30	Diagnostic_procedure:T50 
T51	Lab_value 964 973	<20 mg/dL
R6	MODIFY Arg1:T51 Arg2:E29	
T52	Lab_value 978 988	<167 mg/dL
R7	MODIFY Arg1:T52 Arg2:E30	
R8	MODIFY Arg1:T44 Arg2:E28	
R9	IDENTICAL Arg1:T43 Arg2:T44	
R10	MODIFY Arg1:T46 Arg2:E28	
R11	MODIFY Arg1:T47 Arg2:E28	
R12	MODIFY Arg1:T48 Arg2:E28	
R13	MODIFY Arg1:T44 Arg2:E29	
R14	MODIFY Arg1:T44 Arg2:E30	
T53	Diagnostic_procedure 1004 1014	Gram stain
E31	Diagnostic_procedure:T53 
T54	Biological_structure 1018 1021	CSF
T55	Sign_symptom 1029 1057	gram-positive cocci in pairs
E32	Sign_symptom:T55 
R15	MODIFY Arg1:T54 Arg2:E31	
T56	Medication 1085 1096	ceftriaxone
E33	Medication:T56 
T57	Medication 1098 1108	vancomycin
E34	Medication:T57 
T58	Medication 1114 1124	ampicillin
E35	Medication:T58 
T59	Disease_disorder 1130 1150	bacterial meningitis
E36	Disease_disorder:T59 
T60	Diagnostic_procedure 1162 1187	Computed tomographic scan
E37	Diagnostic_procedure:T60 
T61	Biological_structure 1195 1199	head
R16	MODIFY Arg1:T61 Arg2:E37	
T62	Sign_symptom 1212 1221	sinusitis
E38	Sign_symptom:T62 
T63	Diagnostic_procedure 1241 1251	radiograph
E39	Diagnostic_procedure:T63 
T64	Biological_structure 1235 1240	chest
R17	MODIFY Arg1:T64 Arg2:E39	
T65	Diagnostic_procedure 1256 1286	transesophageal echocardiogram
E40	Diagnostic_procedure:T65 
T66	Lab_value 1292 1300	negative
R18	MODIFY Arg1:T66 Arg2:E40	
R19	MODIFY Arg1:T66 Arg2:E39	
T67	Date 1305 1319	hospital day 2
E41	Date:T67 
T68	Diagnostic_procedure 1321 1335	blood cultures
E42	Diagnostic_procedure:T68 
T69	Sign_symptom 1341 1360	gram-positive cocci
E43	Sign_symptom:T69 
T70	Detailed_description 1364 1369	pairs
R20	MODIFY Arg1:T70 Arg2:E43	
T71	Detailed_description 1374 1380	chains
R21	MODIFY Arg1:T71 Arg2:E43	
T72	Sign_symptom 1386 1394	organism
E44	Sign_symptom:T72 
T73	Diagnostic_procedure 1399 1407	catalase
E45	Diagnostic_procedure:T73 
T74	Lab_value 1408 1416	negative
R22	MODIFY Arg1:T74 Arg2:E45	
T75	Diagnostic_procedure 1418 1430	bile esculin
E46	Diagnostic_procedure:T75 
T76	Lab_value 1431 1439	negative
R23	MODIFY Arg1:T76 Arg2:E46	
T77	Diagnostic_procedure 1445 1472	pyrrolidonyl aminopeptidase
E47	Diagnostic_procedure:T77 
T78	Lab_value 1473 1481	negative
R24	MODIFY Arg1:T78 Arg2:E47	
T79	Sign_symptom 1499 1516	Streptococcus spp
E48	Sign_symptom:T79 
R25	MODIFY Arg1:E45 Arg2:E44	
R26	MODIFY Arg1:E46 Arg2:E44	
R27	MODIFY Arg1:E47 Arg2:E44	
T80	Diagnostic_procedure 1520 1544	latex agglutination test
E49	Diagnostic_procedure:T80 
T81	Sign_symptom 1560 1592	Streptococcus pneumoniae antigen
E50	Sign_symptom:T81 
A2	POLARITY E50 NEG
T82	Diagnostic_procedure 1594 1630	Antimicrobial susceptibility testing
E51	Diagnostic_procedure:T82 
T83	Sign_symptom 1659 1724	sensitive to penicillin (MIC = 0.03), ceftriaxone, and vancomycin
E52	Sign_symptom:T83 
T84	Sign_symptom 1729 1770	resistant to tetracycline and clindamycin
E53	Sign_symptom:T84 
T85	Coreference 1647 1654	isolate
E54	Coreference:T85 
R28	IDENTICAL Arg1:E54 Arg2:E44	
R29	MODIFY Arg1:E52 Arg2:E54	
R30	MODIFY Arg1:E53 Arg2:E54	
T86	Medication 1772 1793	Antimicrobial therapy
E55	Medication:T86 
T87	Medication 1809 1821	penicillin G
E56	Medication:T87 
T88	Dosage 1823 1839	24 million units
T89	Administration 1840 1853	intravenously
T90	Frequency 1854 1861	per day
R31	MODIFY Arg1:T88 Arg2:E56	
R32	MODIFY Arg1:T89 Arg2:E56	
R33	MODIFY Arg1:T90 Arg2:E56	
T91	Date 1866 1880	hospital day 5
E57	Date:T91 
R34	SUB_PROCEDURE Arg1:E56 Arg2:E55	
T92	Sign_symptom 1908 1920	hearing loss
E58	Sign_symptom:T92 
T93	Biological_structure 1928 1936	left ear
R35	MODIFY Arg1:T93 Arg2:E58	
T94	Diagnostic_procedure 1949 1973	nasopharyngeal endoscopy
E59	Diagnostic_procedure:T94 
T95	Lab_value 1979 1987	negative
R36	MODIFY Arg1:T95 Arg2:E59	
T96	Date 1992 2006	hospital day 7
E60	Date:T96 
T97	Diagnostic_procedure 2043 2062	API 20 Strep System
E61	Diagnostic_procedure:T97 
T98	Sign_symptom 2104 2122	S. suis serotype 2
E62	Sign_symptom:T98 
T99	Occupation 2170 2177	butcher
T100	Detailed_description 2185 2231	culinary preference for partially cooked pork,
R37	MODIFY Arg1:T100 Arg2:T99	
T101	Date 2270 2311	until the week prior to onset of symptoms
E63	Date:T101 
T103	Nonbiological_location 2258 2269	Philippines
T104	Other_entity 2209 2230	partially cooked pork
T105	Date 2316 2330	hospital day 9
E64	Date:T105 
T106	Diagnostic_procedure 2334 2361	formal audiology evaluation
E65	Diagnostic_procedure:T106 
T107	Sign_symptom 2376 2427	bilateral sensorineural high-frequency hearing loss
E66	Sign_symptom:T107 
T108	Severity 2369 2375	severe
R40	MODIFY Arg1:T108 Arg2:E66	
T109	Lab_value 2429 2435	–70 dB
R41	MODIFY Arg1:T109 Arg2:E66	
T110	Duration 2462 2475	10-day course
E67	Duration:T110 
T111	Medication 2479 2509	parenteral antimicrobial drugs
E68	Medication:T111 
T112	Clinical_event 2518 2528	discharged
E69	Clinical_event:T112 
T113	Medication 2542 2554	oral therapy
E70	Medication:T113 
T114	Detailed_description 2532 2541	continued
R42	MODIFY Arg1:T114 Arg2:E70	
T115	Date 2576 2602	Two months after discharge
E71	Date:T115 
T116	Sign_symptom 2625 2646	much improved hearing
E72	Sign_symptom:T116 
T117	Sign_symptom 2661 2669	sequelae
E73	Sign_symptom:T117 
A3	POLARITY E73 NEG
T118	Coreference 2012 2020	organism
E74	Coreference:T118 
R43	IDENTICAL Arg1:E74 Arg2:E44	
*	OVERLAP E2 E1
R45	BEFORE Arg1:E1 Arg2:E3	
*	OVERLAP E3 E4 E5 E6 E7 E8 E9
R46	AFTER Arg1:E9 Arg2:E11	
T17	Activity 260 268	vacation
E75	Activity:T17 
R2	MODIFY Arg1:E10 Arg2:E75	
R44	MODIFY Arg1:T18 Arg2:E75	
*	OVERLAP E11 E75
R47	BEFORE Arg1:E75 Arg2:E12	
*	OVERLAP E12 E13
T119	Sign_symptom 360 378	Symptoms continued
E76	Sign_symptom:T119 
R48	BEFORE Arg1:E13 Arg2:E76	
R49	MODIFY Arg1:T23 Arg2:E14	
*	OVERLAP E76 E14 E15 E16 E17 E18 E19 E20 E21 E22 E24 E25 E26 E27 E28 E29 E30 E31 E32
R50	MODIFY Arg1:T40 Arg2:E26	
R51	MODIFY Arg1:T42 Arg2:E27	
R52	BEFORE Arg1:E32 Arg2:E33	
*	OVERLAP E33 E34 E35 E36 E37 E38 E39 E40
R53	BEFORE Arg1:E40 Arg2:E41	
*	OVERLAP E41 E42 E43 E44 E48 E49 E50 E51 E54 E55
R54	BEFORE Arg1:E55 Arg2:E57	
*	OVERLAP E57 E58 E59
R55	BEFORE Arg1:E59 Arg2:E60	
*	OVERLAP E60 E74 E61 E62
R58	BEFORE Arg1:E63 Arg2:E64	
*	OVERLAP E64 E65 E66
R59	BEFORE Arg1:E66 Arg2:E67	
*	OVERLAP E67 E68 E69 E70
R60	BEFORE Arg1:E70 Arg2:E71	
*	OVERLAP E71 E72 E73
T4	Activity 2245 2250	eaten
E77	Activity:T4 
R38	MODIFY Arg1:T104 Arg2:E77	
R39	MODIFY Arg1:T103 Arg2:E77	
R56	AFTER Arg1:E62 Arg2:E77	
R57	BEFORE Arg1:E77 Arg2:E63