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T1 Age 8 19 28-year-old T2 History 20 38 previously healthy T3 Sex 39 42 man T4 Clinical_event 43 52 presented E1 Clinical_event:T4 T5 Sign_symptom 31 38 healthy E2 Sign_symptom:T5 T6 Duration 60 66 6-week E3 Duration:T6 T7 Sign_symptom 78 90 palpitations E4 Sign_symptom:T7 T8 Coreference 96 104 symptoms E5 Coreference:T8 R1 IDENTICAL Arg1:E5 Arg2:E4 T9 Clinical_event 121 125 rest E6 Clinical_event:T9 R2 MODIFY Arg1:E6 Arg2:E5 T10 Frequency 127 145 2–3 times per week R3 MODIFY Arg1:T10 Arg2:E5 T12 Sign_symptom 206 213 dyspnea E8 Sign_symptom:T12 T11 Detailed_description 154 180 up to 30 minutes at a time R4 MODIFY Arg1:T11 Arg2:E5 T13 Sign_symptom 261 281 regurgitation murmur E7 Sign_symptom:T13 T14 Biological_structure 251 260 tricuspid T15 Detailed_description 238 250 holosystolic T16 Lab_value 228 237 grade 2/6 R5 MODIFY Arg1:T14 Arg2:E7 R6 MODIFY Arg1:T15 Arg2:E7 R7 MODIFY Arg1:T16 Arg2:E7 T17 Biological_structure 301 320 left sternal border R8 MODIFY Arg1:T17 Arg2:E7 T18 Detailed_description 326 350 inspiratory accentuation R9 MODIFY Arg1:T18 Arg2:E7 T19 Diagnostic_procedure 353 373 physical examination E9 Diagnostic_procedure:T19 T21 Diagnostic_procedure 408 425 electrocardiogram E10 Diagnostic_procedure:T21 T22 Diagnostic_procedure 427 430 ECG E11 Diagnostic_procedure:T22 R11 IDENTICAL Arg1:E11 Arg2:E10 T23 Diagnostic_procedure 448 460 sinus rhythm E12 Diagnostic_procedure:T23 R12 SUB_PROCEDURE Arg1:E12 Arg2:E10 T25 Sign_symptom 467 513 Wolff– Parkinson– White pre-excitation pattern E13 Sign_symptom:T25 T26 Disease_disorder 554 571 accessory pathway E14 Disease_disorder:T26 R14 CAUSE Arg1:E14 Arg2:E13 T27 Detailed_description 542 553 right-sided R15 MODIFY Arg1:T27 Arg2:E14 T28 Diagnostic_procedure 587 603 echocardiography E15 Diagnostic_procedure:T28 T29 Biological_structure 573 586 Transthoracic R16 MODIFY Arg1:T29 Arg2:E15 T30 Disease_disorder 633 650 Ebstein's anomaly E16 Disease_disorder:T30 T31 Biological_structure 658 673 tricuspid valve R17 MODIFY Arg1:T31 Arg2:E16 T32 Sign_symptom 680 699 apical displacement E17 Sign_symptom:T32 T33 Coreference 707 712 valve E18 Coreference:T33 R18 IDENTICAL Arg1:E18 Arg2:T31 R19 MODIFY Arg1:E18 Arg2:E17 T34 Disease_disorder 734 744 atrialized E19 Disease_disorder:T34 T35 Biological_structure 746 761 right ventricle R20 MODIFY Arg1:T35 Arg2:E19 T36 Biological_structure 793 805 right atrium T37 Biological_structure 844 859 right ventricle T38 Biological_structure 814 819 inlet R21 MODIFY Arg1:T38 Arg2:T37 R22 MODIFY Arg1:T37 Arg2:E19 R23 MODIFY Arg1:T36 Arg2:E19 T39 Sign_symptom 911 920 elongated E20 Sign_symptom:T39 T40 Biological_structure 874 906 anterior tricuspid valve leaflet R24 MODIFY Arg1:T40 Arg2:E20 T41 Sign_symptom 969 980 rudimentary E21 Sign_symptom:T41 T42 Biological_structure 950 964 septal leaflet R25 MODIFY Arg1:T42 Arg2:E21 T43 Diagnostic_procedure 1011 1027 echocardiography E22 Diagnostic_procedure:T43 T44 Detailed_description 1002 1010 Contrast R26 MODIFY Arg1:T44 Arg2:E22 T45 Detailed_description 1028 1040 using saline R27 MODIFY Arg1:T45 Arg2:E22 T46 Disease_disorder 1052 1072 patent foramen ovale E23 Disease_disorder:T46 T47 Sign_symptom 1078 1100 right-to-left shunting E24 Sign_symptom:T47 T48 Sign_symptom 1105 1112 bubbles E25 Sign_symptom:T48 T49 Biological_structure 1120 1131 left atrium R28 MODIFY Arg1:T49 Arg2:E25 T50 Diagnostic_procedure 1167 1191 electrophysiologic study E26 Diagnostic_procedure:T50 T51 Diagnostic_procedure 1197 1204 mapping E27 Diagnostic_procedure:T51 T52 Biological_structure 1212 1229 accessory pathway R29 MODIFY Arg1:T52 Arg2:E27 T53 Therapeutic_procedure 1258 1266 ablation E28 Therapeutic_procedure:T53 T54 Detailed_description 1243 1257 radiofrequency R30 MODIFY Arg1:T54 Arg2:E28 T55 Therapeutic_procedure 1363 1380 ablation catheter E29 Therapeutic_procedure:T55 R31 SUB_PROCEDURE Arg1:E29 Arg2:E28 T56 Diagnostic_procedure 1401 1404 ECG E30 Diagnostic_procedure:T56 T57 Diagnostic_procedure 1424 1435 PR interval E31 Diagnostic_procedure:T57 T59 Diagnostic_procedure 1456 1467 QRS complex E32 Diagnostic_procedure:T59 T62 Detailed_description 1471 1495 leads III, aVF and V2–V4 R35 MODIFY Arg1:T62 Arg2:E32 T63 Disease_disorder 1528 1555 abnormal impulse conduction E33 Disease_disorder:T63 T64 Disease_disorder 1564 1574 atrialized E34 Disease_disorder:T64 T65 Biological_structure 1576 1591 right ventricle R36 MODIFY Arg1:T65 Arg2:E34 T66 Sign_symptom 1631 1643 palpitations E35 Sign_symptom:T66 A1 POLARITY E35 NEG T67 Clinical_event 1647 1656 follow-up E36 Clinical_event:T67 T68 Date 1657 1671 6 months after E37 Date:T68 R37 BEFORE Arg1:E2 Arg2:E1 R38 AFTER Arg1:E1 Arg2:E3 * OVERLAP E3 E4 E5 E6 E8 R39 BEFORE Arg1:E8 Arg2:E7 * OVERLAP E7 E9 E10 E13 E14 E15 E16 E17 E19 E20 E21 E22 E23 E24 E25 R40 BEFORE Arg1:E25 Arg2:E26 * OVERLAP E26 E27 R41 BEFORE Arg1:E27 Arg2:E28 R42 BEFORE Arg1:E28 Arg2:E30 * OVERLAP E30 E31 E32 E33 E34 R43 BEFORE Arg1:E34 Arg2:E35 * OVERLAP E35 E36 E37 T20 Lab_value 382 394 unremarkable E38 Lab_value:T20 R10 MODIFY Arg1:E38 Arg2:E9 T24 Lab_value 441 447 normal E39 Lab_value:T24 R13 MODIFY Arg1:E39 Arg2:E12 T58 Lab_value 1414 1423 prolonged E40 Lab_value:T58 R32 MODIFY Arg1:E40 Arg2:E31 T60 Lab_value 1447 1455 “second” E41 Lab_value:T60 T61 Lab_value 1443 1446 odd E42 Lab_value:T61 R33 MODIFY Arg1:E41 Arg2:E32 R34 MODIFY Arg1:E42 Arg2:E32