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| # | sentence | tags | tokens | numeric_tags |
|---|---|---|---|---|
| 1 | CASE: A 28-year-old previously healthy man presented with a 6-week history of palpitations. | ['O', 'O', 'B-Age', 'B-History', 'I-History', 'B-Sex', 'B-Clinical_event', 'O', 'O', 'B-Duration', 'O', 'O', 'B-Sign_symptom'] | ['case', 'a', '28-year-old', 'previously', 'healthy', 'man', 'presented', 'with', 'a', '6-week', 'history', 'of', 'palpitations'] | [0, 0, 1, 15, 16, 3, 5, 0, 0, 37, 0, 0, 9] |
| 2 | The symptoms occurred during rest, 2–3 times per week, lasted up to 30 minutes at a time and were associated with dyspnea. | ['O', 'B-Coreference', 'O', 'O', 'B-Clinical_event', 'B-Frequency', 'I-Frequency', 'I-Frequency', 'I-Frequency', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'O', 'I-Detailed_description', 'O', 'O', 'O', 'O', 'B-Sign_symptom'] | ['the', 'symptoms', 'occurred', 'during', 'rest', '2–3', 'times', 'per', 'week', 'lasted', 'up', 'to', '30', 'minutes', 'at', 'a', 'time', 'and', 'were', 'associated', 'with', 'dyspnea'] | [0, 29, 0, 0, 5, 43, 44, 44, 44, 0, 13, 14, 14, 14, 14, 0, 14, 0, 0, 0, 0, 9] |
| 3 | Except for a grade 2/6 holosystolic tricuspid regurgitation murmur (best heard at the left sternal border with inspiratory accentuation), physical examination yielded unremarkable findings. | ['O', 'O', 'O', 'B-Lab_value', 'I-Lab_value', 'B-Detailed_description', 'B-Biological_structure', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'O', 'B-Detailed_description', 'I-Detailed_description', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value', 'O'] | ['except', 'for', 'a', 'grade', '2/6', 'holosystolic', 'tricuspid', 'regurgitation', 'murmur', 'best', 'heard', 'at', 'the', 'left', 'sternal', 'border', 'with', 'inspiratory', 'accentuation', 'physical', 'examination', 'yielded', 'unremarkable', 'findings'] | [0, 0, 0, 23, 24, 13, 11, 9, 10, 0, 0, 0, 0, 11, 12, 12, 0, 13, 14, 19, 20, 0, 23, 0] |
| 4 | An electrocardiogram (ECG) revealed normal sinus rhythm and a Wolff– Parkinson– White pre-excitation pattern (Fig.1: Top), produced by a right-sided accessory pathway. | ['O', 'B-Diagnostic_procedure', 'O', 'O', 'B-Lab_value', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'B-Disease_disorder', 'I-Disease_disorder'] | ['an', 'electrocardiogram', 'ecg', 'revealed', 'normal', 'sinus', 'rhythm', 'and', 'a', 'wolff–', 'parkinson–', 'white', 'pre-excitation', 'pattern', 'fig1', 'top', 'produced', 'by', 'a', 'right-sided', 'accessory', 'pathway'] | [0, 19, 0, 0, 23, 19, 20, 0, 0, 9, 10, 10, 10, 10, 0, 0, 0, 0, 0, 13, 25, 26] |
| 5 | Transthoracic echocardiography demonstrated the presence of Ebstein's anomaly of the tricuspid valve, with apical displacement of the valve and formation of an “atrialized” right ventricle (a functional unit between the right atrium and the inlet [inflow] portion of the right ventricle) (Fig.2). | ['B-Biological_structure', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'B-Disease_disorder', 'I-Disease_disorder', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'B-Coreference', 'O', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O'] | ['transthoracic', 'echocardiography', 'demonstrated', 'the', 'presence', 'of', "ebstein's", 'anomaly', 'of', 'the', 'tricuspid', 'valve', 'with', 'apical', 'displacement', 'of', 'the', 'valve', 'and', 'formation', 'of', 'an', '“atrialized”', 'right', 'ventricle', 'a', 'functional', 'unit', 'between', 'the', 'right', 'atrium', 'and', 'the', 'inlet', 'inflow', 'portion', 'of', 'the', 'right', 'ventricle', 'fig2'] | [11, 19, 0, 0, 0, 0, 25, 26, 0, 0, 11, 12, 0, 9, 10, 0, 0, 29, 0, 0, 0, 0, 0, 11, 12, 0, 0, 0, 0, 0, 11, 12, 0, 0, 11, 0, 0, 0, 0, 11, 12, 0] |
| 6 | The anterior tricuspid valve leaflet was elongated (Fig.2C, arrow), whereas the septal leaflet was rudimentary (Fig.2C, arrowhead). | ['O', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'O', 'B-Sign_symptom', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O', 'B-Sign_symptom', 'O', 'O'] | ['the', 'anterior', 'tricuspid', 'valve', 'leaflet', 'was', 'elongated', 'fig2c', 'arrow', 'whereas', 'the', 'septal', 'leaflet', 'was', 'rudimentary', 'fig2c', 'arrowhead'] | [0, 11, 12, 12, 12, 0, 9, 0, 0, 0, 0, 11, 12, 0, 9, 0, 0] |
| 7 | Contrast echocardiography using saline revealed a patent foramen ovale with right-to-left shunting and bubbles in the left atrium (Fig.2D). | ['B-Detailed_description', 'B-Diagnostic_procedure', 'B-Detailed_description', 'I-Detailed_description', 'O', 'O', 'B-Disease_disorder', 'I-Disease_disorder', 'I-Disease_disorder', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O'] | ['contrast', 'echocardiography', 'using', 'saline', 'revealed', 'a', 'patent', 'foramen', 'ovale', 'with', 'right-to-left', 'shunting', 'and', 'bubbles', 'in', 'the', 'left', 'atrium', 'fig2d'] | [13, 19, 13, 14, 0, 0, 25, 26, 26, 0, 9, 10, 0, 9, 0, 0, 11, 12, 0] |
| 8 | The patient underwent an electrophysiologic study with mapping of the accessory pathway, followed by radiofrequency ablation (interruption of the pathway using the heat generated by electromagnetic waves at the tip of an ablation catheter). | ['O', 'O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O', 'O', 'B-Detailed_description', 'B-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure'] | ['the', 'patient', 'underwent', 'an', 'electrophysiologic', 'study', 'with', 'mapping', 'of', 'the', 'accessory', 'pathway', 'followed', 'by', 'radiofrequency', 'ablation', 'interruption', 'of', 'the', 'pathway', 'using', 'the', 'heat', 'generated', 'by', 'electromagnetic', 'waves', 'at', 'the', 'tip', 'of', 'an', 'ablation', 'catheter'] | [0, 0, 0, 0, 19, 20, 0, 19, 0, 0, 11, 12, 0, 0, 13, 33, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 33, 34] |
| 9 | His post-ablation ECG showed a prolonged PR interval and an odd “second” QRS complex in leads III, aVF and V2–V4 (Fig.1Bottom), a consequence of abnormal impulse conduction in the “atrialized” right ventricle. | ['O', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'B-Lab_value', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Lab_value', 'B-Lab_value', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Detailed_description', 'O', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'O', 'O', 'O', 'O', 'B-Disease_disorder', 'I-Disease_disorder', 'I-Disease_disorder', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure'] | ['his', 'post-ablation', 'ecg', 'showed', 'a', 'prolonged', 'pr', 'interval', 'and', 'an', 'odd', '“second”', 'qrs', 'complex', 'in', 'leads', 'iii', 'avf', 'and', 'v2–v4', 'fig1bottom', 'a', 'consequence', 'of', 'abnormal', 'impulse', 'conduction', 'in', 'the', '“atrialized”', 'right', 'ventricle'] | [0, 0, 19, 0, 0, 23, 19, 20, 0, 0, 23, 23, 19, 20, 0, 13, 0, 14, 14, 14, 0, 0, 0, 0, 25, 26, 26, 0, 0, 0, 11, 12] |
| 10 | The patient reported no recurrence of palpitations at follow-up 6 months after the ablation. | ['O', 'O', 'O', 'O', 'O', 'O', 'B-Sign_symptom', 'O', 'B-Clinical_event', 'B-Date', 'I-Date', 'I-Date', 'O', 'O'] | ['the', 'patient', 'reported', 'no', 'recurrence', 'of', 'palpitations', 'at', 'follow-up', '6', 'months', 'after', 'the', 'ablation'] | [0, 0, 0, 0, 0, 0, 9, 0, 5, 39, 40, 40, 0, 0] |
| 11 | The patient was a 34-yr-old man who presented with complaints of fever and a chronic cough. | ['O', 'O', 'O', 'O', 'B-Age', 'B-Sex', 'O', 'B-Clinical_event', 'O', 'O', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Detailed_description', 'B-Sign_symptom'] | ['the', 'patient', 'was', 'a', '34-yr-old', 'man', 'who', 'presented', 'with', 'complaints', 'of', 'fever', 'and', 'a', 'chronic', 'cough'] | [0, 0, 0, 0, 1, 3, 0, 5, 0, 0, 0, 9, 0, 0, 13, 9] |
| 12 | He was a smoker and had a history of pulmonary tuberculosis that had been treated and cured. | ['O', 'O', 'O', 'B-History', 'O', 'O', 'O', 'B-History', 'I-History', 'I-History', 'I-History', 'O', 'O', 'O', 'B-Lab_value', 'I-Lab_value', 'I-Lab_value'] | ['he', 'was', 'a', 'smoker', 'and', 'had', 'a', 'history', 'of', 'pulmonary', 'tuberculosis', 'that', 'had', 'been', 'treated', 'and', 'cured'] | [0, 0, 0, 15, 0, 0, 0, 15, 16, 16, 16, 0, 0, 0, 23, 24, 24] |
| 13 | A computed tomographic (CT) scan revealed multiple tiny nodules in both lungs. | ['O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'B-Detailed_description', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'B-Biological_structure', 'I-Biological_structure'] | ['a', 'computed', 'tomographic', 'ct', 'scan', 'revealed', 'multiple', 'tiny', 'nodules', 'in', 'both', 'lungs'] | [0, 19, 20, 0, 0, 0, 13, 13, 9, 0, 11, 12] |
| 14 | A thoracoscopic lung biopsy was taken from the right upper lobe. | ['O', 'B-Detailed_description', 'B-Biological_structure', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure'] | ['a', 'thoracoscopic', 'lung', 'biopsy', 'was', 'taken', 'from', 'the', 'right', 'upper', 'lobe'] | [0, 13, 11, 19, 0, 0, 0, 0, 11, 12, 12] |
| 15 | The microscopic examination revealed a typical LCH. | ['O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'B-Sign_symptom'] | ['the', 'microscopic', 'examination', 'revealed', 'a', 'typical', 'lch'] | [0, 19, 20, 0, 0, 0, 9] |
| 16 | The tumor cells had vesicular and grooved nuclei, and they formed small aggregations around the bronchioles (Fig.1). | ['O', 'B-Coreference', 'I-Coreference', 'O', 'B-Detailed_description', 'O', 'B-Texture', 'B-Biological_structure', 'O', 'O', 'O', 'B-Biological_attribute', 'B-Biological_attribute', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'O'] | ['the', 'tumor', 'cells', 'had', 'vesicular', 'and', 'grooved', 'nuclei', 'and', 'they', 'formed', 'small', 'aggregations', 'around', 'the', 'bronchioles', 'fig1'] | [0, 29, 30, 0, 13, 0, 45, 11, 0, 0, 0, 47, 47, 11, 12, 12, 0] |
| 17 | The tumor cells were strongly positive for S-100 protein, vimentin, CD68 and CD1a. | ['O', 'B-Coreference', 'I-Coreference', 'O', 'B-Severity', 'B-Lab_value', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Diagnostic_procedure', 'B-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure'] | ['the', 'tumor', 'cells', 'were', 'strongly', 'positive', 'for', 's-100', 'protein', 'vimentin', 'cd68', 'and', 'cd1a'] | [0, 29, 30, 0, 49, 23, 0, 19, 20, 19, 19, 0, 19] |
| 18 | There were infiltrations of lymphocytes and eosinophils around the tumor cells. | ['O', 'O', 'B-Biological_structure', 'O', 'B-Biological_structure', 'O', 'B-Biological_structure', 'O', 'O', 'B-Coreference', 'I-Coreference'] | ['there', 'were', 'infiltrations', 'of', 'lymphocytes', 'and', 'eosinophils', 'around', 'the', 'tumor', 'cells'] | [0, 0, 11, 0, 11, 0, 11, 0, 0, 29, 30] |
| 19 | With performing additional radiologic examinations, no other organs were thought to be involved. | ['O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['with', 'performing', 'additional', 'radiologic', 'examinations', 'no', 'other', 'organs', 'were', 'thought', 'to', 'be', 'involved'] | [0, 0, 0, 19, 20, 9, 10, 10, 10, 10, 10, 10, 10] |
| 20 | He quit smoking, but he received no other specific treatment. | ['O', 'B-Activity', 'I-Activity', 'O', 'O', 'O', 'O', 'O', 'O', 'O'] | ['he', 'quit', 'smoking', 'but', 'he', 'received', 'no', 'other', 'specific', 'treatment'] | [0, 51, 52, 0, 0, 0, 0, 0, 0, 0] |
| 21 | He was well for the following one year. | ['O', 'O', 'B-Sign_symptom', 'B-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'I-Duration'] | ['he', 'was', 'well', 'for', 'the', 'following', 'one', 'year'] | [0, 0, 9, 37, 38, 38, 38, 38] |
| 22 | After this, a follow-up CT scan was performed and it showed a 4 cm-sized mass in the left lower lobe, in addition to the multiple tiny nodules in both lungs (Fig.2). | ['O', 'O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Shape', 'I-Shape', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O'] | ['after', 'this', 'a', 'follow-up', 'ct', 'scan', 'was', 'performed', 'and', 'it', 'showed', 'a', '4', 'cm-sized', 'mass', 'in', 'the', 'left', 'lower', 'lobe', 'in', 'addition', 'to', 'the', 'multiple', 'tiny', 'nodules', 'in', 'both', 'lungs', 'fig2'] | [0, 0, 0, 0, 19, 20, 0, 0, 0, 0, 0, 0, 27, 28, 9, 0, 0, 11, 12, 12, 0, 0, 0, 0, 13, 13, 9, 0, 11, 12, 0] |
| 23 | A needle biopsy specimen revealed the possibility of a sarcoma; therefore, a lobectomy was performed. | ['O', 'B-Detailed_description', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'B-Therapeutic_procedure', 'O', 'O'] | ['a', 'needle', 'biopsy', 'specimen', 'revealed', 'the', 'possibility', 'of', 'a', 'sarcoma', 'therefore', 'a', 'lobectomy', 'was', 'performed'] | [0, 13, 19, 0, 0, 0, 9, 10, 10, 10, 0, 0, 33, 0, 0] |
| 24 | Grossly, a 4 cm-sized poorly-circumscribed lobulated gray-white mass was found (Fig.3), and there were a few small satellite nodules around the main mass. | ['O', 'O', 'B-Shape', 'I-Shape', 'B-Detailed_description', 'B-Detailed_description', 'B-Color', 'B-Sign_symptom', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'O', 'B-Coreference', 'I-Coreference'] | ['grossly', 'a', '4', 'cm-sized', 'poorly-circumscribed', 'lobulated', 'gray-white', 'mass', 'was', 'found', 'fig3', 'and', 'there', 'were', 'a', 'few', 'small', 'satellite', 'nodules', 'around', 'the', 'main', 'mass'] | [0, 0, 27, 28, 13, 13, 41, 9, 0, 0, 0, 0, 0, 0, 0, 0, 13, 13, 9, 0, 0, 29, 30] |
| 25 | Microscopically, the tumor cells were aggregated in large sheets and they showed an infiltrative growth. | ['B-Diagnostic_procedure', 'O', 'B-Coreference', 'I-Coreference', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure'] | ['microscopically', 'the', 'tumor', 'cells', 'were', 'aggregated', 'in', 'large', 'sheets', 'and', 'they', 'showed', 'an', 'infiltrative', 'growth'] | [19, 0, 29, 30, 0, 13, 14, 14, 14, 0, 0, 0, 0, 11, 12] |
| 26 | The cytologic features of some of the tumor cells were similar to those seen in a typical LCH. | ['O', 'B-Biological_attribute', 'I-Biological_attribute', 'O', 'O', 'O', 'O', 'B-Coreference', 'I-Coreference', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'O', 'I-Detailed_description', 'I-Detailed_description'] | ['the', 'cytologic', 'features', 'of', 'some', 'of', 'the', 'tumor', 'cells', 'were', 'similar', 'to', 'those', 'seen', 'in', 'a', 'typical', 'lch'] | [0, 47, 48, 0, 0, 0, 0, 29, 30, 0, 13, 14, 14, 14, 14, 0, 14, 14] |
| 27 | However, many tumor cells showed overtly malignant cytologic features such as pleomorphic/hyperchromatic nuclei and prominent nucleoli (Fig.4), and multinucleated tumor giant cells were also found. | ['O', 'O', 'B-Coreference', 'I-Coreference', 'O', 'O', 'O', 'B-Biological_attribute', 'I-Biological_attribute', 'O', 'O', 'B-Detailed_description', 'B-Biological_structure', 'O', 'B-Detailed_description', 'B-Biological_attribute', 'O', 'O', 'B-Detailed_description', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'O', 'O', 'O'] | ['however', 'many', 'tumor', 'cells', 'showed', 'overtly', 'malignant', 'cytologic', 'features', 'such', 'as', 'pleomorphic/hyperchromatic', 'nuclei', 'and', 'prominent', 'nucleoli', 'fig4', 'and', 'multinucleated', 'tumor', 'giant', 'cells', 'were', 'also', 'found'] | [0, 0, 29, 30, 0, 0, 0, 47, 48, 0, 0, 13, 11, 0, 13, 47, 0, 0, 13, 11, 12, 12, 0, 0, 0] |
| 28 | There were numerous mitotic figures ranging from 30 to 60 per 10 high power fields, and some of them were abnormal. | ['O', 'O', 'B-Detailed_description', 'B-Biological_structure', 'I-Biological_structure', 'O', 'O', 'B-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description'] | ['there', 'were', 'numerous', 'mitotic', 'figures', 'ranging', 'from', '30', 'to', '60', 'per', '10', 'high', 'power', 'fields', 'and', 'some', 'of', 'them', 'were', 'abnormal'] | [0, 0, 13, 11, 12, 0, 0, 23, 24, 24, 24, 24, 24, 24, 24, 0, 13, 14, 14, 14, 14] |
| 29 | A few foci of typical LCH remained around the main tumor mass. | ['O', 'B-Detailed_description', 'I-Detailed_description', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description'] | ['a', 'few', 'foci', 'of', 'typical', 'lch', 'remained', 'around', 'the', 'main', 'tumor', 'mass'] | [0, 13, 14, 0, 9, 10, 0, 13, 14, 14, 14, 14] |
| 30 | Immunohistochemically, the tumor cells were strongly positive for S-100 protein (Fig.5) and vimentin; they were also positive for CD68 (Dako N1577, Clone KPI), and focally positive for CD1a (Fig.6), and they were negative for cytokeratin, epithelial membrane antigen, CD3, CD20 and HMB45. | ['B-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'B-Severity', 'B-Lab_value', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'B-Lab_value', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'B-Lab_value', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'B-Lab_value', 'O', 'B-Diagnostic_procedure', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Diagnostic_procedure', 'B-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure'] | ['immunohistochemically', 'the', 'tumor', 'cells', 'were', 'strongly', 'positive', 'for', 's-100', 'protein', 'fig5', 'and', 'vimentin', 'they', 'were', 'also', 'positive', 'for', 'cd68', 'dako', 'n1577', 'clone', 'kpi', 'and', 'focally', 'positive', 'for', 'cd1a', 'fig6', 'and', 'they', 'were', 'negative', 'for', 'cytokeratin', 'epithelial', 'membrane', 'antigen', 'cd3', 'cd20', 'and', 'hmb45'] | [19, 0, 0, 0, 0, 49, 23, 0, 19, 20, 0, 0, 19, 0, 0, 0, 23, 0, 19, 0, 0, 0, 0, 0, 13, 23, 0, 19, 0, 0, 0, 0, 23, 0, 19, 19, 20, 20, 19, 19, 0, 19] |
| 31 | The ultrastructural analysis failed to demonstrate any Birbeck granules in the cytoplasm of the tumor cells. | ['O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom'] | ['the', 'ultrastructural', 'analysis', 'failed', 'to', 'demonstrate', 'any', 'birbeck', 'granules', 'in', 'the', 'cytoplasm', 'of', 'the', 'tumor', 'cells'] | [0, 19, 20, 9, 10, 10, 10, 10, 10, 0, 0, 11, 0, 0, 9, 10] |
| 32 | Now, at five months after lobectomy, the patient is doing well with no significant change in the radiologic findings. | ['O', 'O', 'B-Date', 'I-Date', 'I-Date', 'B-Coreference', 'O', 'O', 'O', 'B-Outcome', 'I-Outcome', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['now', 'at', 'five', 'months', 'after', 'lobectomy', 'the', 'patient', 'is', 'doing', 'well', 'with', 'no', 'significant', 'change', 'in', 'the', 'radiologic', 'findings'] | [0, 0, 39, 40, 40, 29, 0, 0, 0, 53, 54, 0, 9, 10, 10, 10, 10, 10, 10] |
| 33 | A 23 year old white male with a 4 year history of Crohn's disease presented with an acute two day history of malaise, fever, abdominal pain, vomiting and stomal diarrhoea. | ['O', 'B-Age', 'I-Age', 'I-Age', 'B-Personal_background', 'B-Sex', 'O', 'O', 'B-History', 'I-History', 'I-History', 'I-History', 'I-History', 'I-History', 'B-Clinical_event', 'O', 'O', 'O', 'B-Duration', 'I-Duration', 'O', 'O', 'B-Sign_symptom', 'B-Sign_symptom', 'B-Biological_structure', 'B-Sign_symptom', 'B-Sign_symptom', 'O', 'B-Biological_structure', 'B-Sign_symptom'] | ['a', '23', 'year', 'old', 'white', 'male', 'with', 'a', '4', 'year', 'history', 'of', "crohn's", 'disease', 'presented', 'with', 'an', 'acute', 'two', 'day', 'history', 'of', 'malaise', 'fever', 'abdominal', 'pain', 'vomiting', 'and', 'stomal', 'diarrhoea'] | [0, 1, 2, 2, 55, 3, 0, 0, 15, 16, 16, 16, 16, 16, 5, 0, 0, 0, 37, 38, 0, 0, 9, 9, 11, 9, 9, 0, 11, 9] |
| 34 | He complained of joint pains affecting the shoulders, elbows, wrists, metacarpophalangeals, knees and ankles. | ['O', 'O', 'O', 'B-Biological_structure', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'B-Biological_structure', 'B-Biological_structure', 'B-Biological_structure', 'B-Biological_structure', 'O', 'B-Biological_structure'] | ['he', 'complained', 'of', 'joint', 'pains', 'affecting', 'the', 'shoulders', 'elbows', 'wrists', 'metacarpophalangeals', 'knees', 'and', 'ankles'] | [0, 0, 0, 11, 9, 0, 0, 11, 11, 11, 11, 11, 0, 11] |
| 35 | There was also a rash on the elbows, ankles and feet, which began as erythematous macules and evolved to vesico-pustular lesions followed by crusting. | ['O', 'O', 'O', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'B-Biological_structure', 'O', 'B-Biological_structure', 'O', 'O', 'O', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'O', 'O', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'O', 'B-Sign_symptom'] | ['there', 'was', 'also', 'a', 'rash', 'on', 'the', 'elbows', 'ankles', 'and', 'feet', 'which', 'began', 'as', 'erythematous', 'macules', 'and', 'evolved', 'to', 'vesico-pustular', 'lesions', 'followed', 'by', 'crusting'] | [0, 0, 0, 0, 9, 0, 0, 11, 11, 0, 11, 0, 0, 0, 13, 9, 0, 0, 0, 13, 9, 0, 0, 9] |
| 36 | There was no history of sexual exposure or any intercurrent infection. | ['O', 'O', 'B-History', 'I-History', 'I-History', 'I-History', 'I-History', 'O', 'O', 'O', 'B-Sign_symptom'] | ['there', 'was', 'no', 'history', 'of', 'sexual', 'exposure', 'or', 'any', 'intercurrent', 'infection'] | [0, 0, 15, 16, 16, 16, 16, 0, 0, 0, 9] |
| 37 | He was on no regular medication, but had discontinued Pentasa 4 months earlier. | ['O', 'O', 'O', 'B-Medication', 'I-Medication', 'I-Medication', 'O', 'O', 'O', 'B-Medication', 'B-Date', 'I-Date', 'I-Date'] | ['he', 'was', 'on', 'no', 'regular', 'medication', 'but', 'had', 'discontinued', 'pentasa', '4', 'months', 'earlier'] | [0, 0, 0, 57, 58, 58, 0, 0, 0, 57, 39, 40, 40] |
| 38 | One month earlier he had undergone a laparotomy to excise a complex ileo-cutaneous fistula with blind tracts, and two weeks earlier a defunctioning ileostomy had been created in view of persistent abdominal pain. | ['B-Date', 'I-Date', 'I-Date', 'O', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'O', 'O', 'O', 'B-Detailed_description', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'B-Detailed_description', 'I-Detailed_description', 'O', 'B-Date', 'I-Date', 'I-Date', 'O', 'B-Detailed_description', 'B-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'B-Biological_structure', 'B-Sign_symptom'] | ['one', 'month', 'earlier', 'he', 'had', 'undergone', 'a', 'laparotomy', 'to', 'excise', 'a', 'complex', 'ileo-cutaneous', 'fistula', 'with', 'blind', 'tracts', 'and', 'two', 'weeks', 'earlier', 'a', 'defunctioning', 'ileostomy', 'had', 'been', 'created', 'in', 'view', 'of', 'persistent', 'abdominal', 'pain'] | [39, 40, 40, 0, 0, 0, 0, 33, 0, 0, 0, 13, 13, 9, 0, 13, 14, 0, 39, 40, 40, 0, 13, 33, 0, 0, 0, 0, 0, 0, 13, 11, 9] |
| 39 | The cutaneous fistula had been present for a year, but was associated with a terminal ileal stricture and ileo-rectal fistula of at least 2 years duration. | ['O', 'B-Biological_structure', 'B-Sign_symptom', 'B-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'O', 'I-Duration', 'O', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'B-Biological_structure', 'B-Sign_symptom', 'O', 'B-Biological_structure', 'B-Sign_symptom', 'B-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'I-Duration'] | ['the', 'cutaneous', 'fistula', 'had', 'been', 'present', 'for', 'a', 'year', 'but', 'was', 'associated', 'with', 'a', 'terminal', 'ileal', 'stricture', 'and', 'ileo-rectal', 'fistula', 'of', 'at', 'least', '2', 'years', 'duration'] | [0, 11, 9, 37, 38, 38, 38, 0, 38, 0, 0, 0, 0, 0, 13, 11, 9, 0, 11, 9, 37, 38, 38, 38, 38, 38] |
| 40 | His bowel disease had been resistant to immunosuppressive drugs including azathioprine, corticosteroiods and three infusions of Infliximab a year earlier. | ['O', 'B-Coreference', 'I-Coreference', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Medication', 'B-Medication', 'O', 'B-Dosage', 'I-Dosage', 'O', 'B-Medication', 'B-Date', 'I-Date', 'I-Date'] | ['his', 'bowel', 'disease', 'had', 'been', 'resistant', 'to', 'immunosuppressive', 'drugs', 'including', 'azathioprine', 'corticosteroiods', 'and', 'three', 'infusions', 'of', 'infliximab', 'a', 'year', 'earlier'] | [0, 29, 30, 0, 0, 0, 0, 0, 0, 0, 57, 57, 0, 59, 60, 0, 57, 39, 40, 40] |
| 41 | There had been no extra-intestinal manifestations. | ['O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['there', 'had', 'been', 'no', 'extra-intestinal', 'manifestations'] | [0, 0, 0, 9, 10, 10] |
| 42 | On admission to the hospital, he was thin, afebrile with a resting tachycardia of 125/minute. | ['O', 'B-Clinical_event', 'O', 'O', 'B-Nonbiological_location', 'O', 'O', 'B-Sign_symptom', 'B-Sign_symptom', 'O', 'O', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'B-Lab_value'] | ['on', 'admission', 'to', 'the', 'hospital', 'he', 'was', 'thin', 'afebrile', 'with', 'a', 'resting', 'tachycardia', 'of', '125/minute'] | [0, 5, 0, 0, 7, 0, 0, 9, 9, 0, 0, 13, 9, 0, 23] |
| 43 | The rest of the cardio-respiratory examination was normal. | ['O', 'O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value'] | ['the', 'rest', 'of', 'the', 'cardio-respiratory', 'examination', 'was', 'normal'] | [0, 0, 0, 0, 19, 20, 0, 23] |
| 44 | The abdomen was minimally tender around the ileostomy without guarding or rebound tenderness. | ['O', 'B-Biological_structure', 'O', 'B-Severity', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'B-Detailed_description', 'I-Detailed_description', 'O', 'O', 'O'] | ['the', 'abdomen', 'was', 'minimally', 'tender', 'around', 'the', 'ileostomy', 'without', 'guarding', 'or', 'rebound', 'tenderness'] | [0, 11, 0, 49, 9, 0, 0, 11, 13, 14, 0, 0, 0] |
| 45 | Examination of the skin revealed some pustules and crusts around the elbows, ankles and feet (Fig 1 and 2). | ['B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Sign_symptom', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'B-Biological_structure', 'O', 'B-Biological_structure', 'O', 'O', 'O', 'O', 'O'] | ['examination', 'of', 'the', 'skin', 'revealed', 'some', 'pustules', 'and', 'crusts', 'around', 'the', 'elbows', 'ankles', 'and', 'feet', 'fig', '1', 'and', '2'] | [19, 20, 20, 20, 0, 0, 9, 0, 9, 0, 0, 11, 11, 0, 11, 0, 0, 0, 0, 0] |
| 46 | The buttocks were spared. | ['B-Other_event', 'I-Other_event', 'I-Other_event', 'O'] | ['the', 'buttocks', 'were', 'spared'] | [61, 62, 62, 0] |
| 47 | There were clinical signs of synovitis of the wrists, proximal interphalangeal and metacarpophalangeal joints, and also both ankles. | ['O', 'O', 'O', 'O', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'B-Biological_structure', 'I-Biological_structure', 'O', 'B-Biological_structure', 'B-Biological_structure', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure'] | ['there', 'were', 'clinical', 'signs', 'of', 'synovitis', 'of', 'the', 'wrists', 'proximal', 'interphalangeal', 'and', 'metacarpophalangeal', 'joints', 'and', 'also', 'both', 'ankles'] | [0, 0, 0, 0, 0, 9, 0, 0, 11, 11, 12, 0, 11, 11, 0, 0, 11, 12] |
| 48 | Results of the laboratory tests showed a haemoglobin of 13.1 gm/dl, white blood count 15.8 × 109/L, platelets 585 × 109/L, C- reactive protein 37.7 mg/L and erythrocyte sedimentation rate 69 mm/hr. | ['O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'I-Lab_value', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'I-Lab_value', 'I-Lab_value', 'B-Diagnostic_procedure', 'B-Lab_value', 'I-Lab_value', 'I-Lab_value', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'I-Lab_value', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Lab_value', 'I-Lab_value'] | ['results', 'of', 'the', 'laboratory', 'tests', 'showed', 'a', 'haemoglobin', 'of', '131', 'gm/dl', 'white', 'blood', 'count', '158', '×', '109/l', 'platelets', '585', '×', '109/l', 'c-', 'reactive', 'protein', '377', 'mg/l', 'and', 'erythrocyte', 'sedimentation', 'rate', '69', 'mm/hr'] | [0, 0, 0, 19, 20, 0, 0, 19, 0, 0, 24, 19, 20, 20, 0, 24, 24, 19, 23, 24, 24, 19, 20, 20, 0, 24, 0, 19, 20, 20, 23, 24] |
| 49 | Urea and electrolytes, complement, urine analysis and microscopy were normal. | ['B-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'B-Diagnostic_procedure', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'O', 'B-Lab_value'] | ['urea', 'and', 'electrolytes', 'complement', 'urine', 'analysis', 'and', 'microscopy', 'were', 'normal'] | [19, 0, 19, 19, 19, 20, 0, 19, 0, 23] |
| 50 | Rheumatoid factor, antinuclear and antineutrophil cytoplasmic antibodies, cryoglobulins and Hepatitis B and C serology were negative. | ['B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Detailed_description', 'O', 'B-Detailed_description', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'B-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value'] | ['rheumatoid', 'factor', 'antinuclear', 'and', 'antineutrophil', 'cytoplasmic', 'antibodies', 'cryoglobulins', 'and', 'hepatitis', 'b', 'and', 'c', 'serology', 'were', 'negative'] | [19, 20, 13, 0, 13, 19, 20, 19, 0, 19, 20, 20, 20, 20, 0, 23] |
| 51 | Transthoracic echocardiogram showed no signs of endocarditis, and multiple blood cultures were sterile. | ['B-Biological_structure', 'B-Diagnostic_procedure', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value'] | ['transthoracic', 'echocardiogram', 'showed', 'no', 'signs', 'of', 'endocarditis', 'and', 'multiple', 'blood', 'cultures', 'were', 'sterile'] | [11, 19, 0, 9, 10, 10, 10, 0, 19, 20, 20, 0, 23] |
| 52 | A skin biopsy from the ankle revealed a perivascular lymphohistiocytic infiltrate with prominent neutrophils and associated fibrinoid necrosis of vessels consistent with 'leukocytoclastic' vasculitis. | ['O', 'B-Biological_structure', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'B-Biological_structure', 'B-Biological_structure', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'B-Biological_structure', 'O', 'O', 'O', 'B-Disease_disorder'] | ['a', 'skin', 'biopsy', 'from', 'the', 'ankle', 'revealed', 'a', 'perivascular', 'lymphohistiocytic', 'infiltrate', 'with', 'prominent', 'neutrophils', 'and', 'associated', 'fibrinoid', 'necrosis', 'of', 'vessels', 'consistent', 'with', "'leukocytoclastic'", 'vasculitis'] | [0, 11, 19, 0, 0, 0, 0, 0, 11, 11, 11, 0, 0, 11, 0, 0, 13, 9, 0, 11, 0, 0, 0, 25] |
| 53 | He was commenced on 60 mg prednisolone per day leading to prompt and complete resolution of all features. | ['O', 'O', 'O', 'O', 'B-Dosage', 'I-Dosage', 'B-Medication', 'B-Dosage', 'I-Dosage', 'O', 'O', 'B-Detailed_description', 'O', 'B-Detailed_description', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['he', 'was', 'commenced', 'on', '60', 'mg', 'prednisolone', 'per', 'day', 'leading', 'to', 'prompt', 'and', 'complete', 'resolution', 'of', 'all', 'features'] | [0, 0, 0, 0, 59, 60, 57, 59, 60, 0, 0, 13, 0, 13, 9, 10, 10, 10] |
| 54 | The dose of prednisolone was rapidly tapered over the course of one month by the patient, faster than advised but without any recurrence over the following 3 years. | ['O', 'O', 'O', 'B-Medication', 'O', 'O', 'B-Clinical_event', 'B-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'B-Duration', 'I-Duration', 'I-Duration', 'I-Duration', 'I-Duration'] | ['the', 'dose', 'of', 'prednisolone', 'was', 'rapidly', 'tapered', 'over', 'the', 'course', 'of', 'one', 'month', 'by', 'the', 'patient', 'faster', 'than', 'advised', 'but', 'without', 'any', 'recurrence', 'over', 'the', 'following', '3', 'years'] | [0, 0, 0, 57, 0, 0, 5, 37, 38, 38, 38, 38, 38, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 37, 38, 38, 38, 38] |
| 55 | A 30-year-old female (65 kg) underwent rhinoplasty under general anaesthesia, which was induced using a combination of a bolus of Remifentanyl (0.5 μg/kg) and Propofol 2 mg/kg. | ['O', 'B-Age', 'B-Sex', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'O', 'B-Medication', 'I-Medication', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Medication', 'O', 'I-Dosage', 'O', 'B-Medication', 'B-Dosage', 'I-Dosage'] | ['a', '30-year-old', 'female', '65', 'kg', 'underwent', 'rhinoplasty', 'under', 'general', 'anaesthesia', 'which', 'was', 'induced', 'using', 'a', 'combination', 'of', 'a', 'bolus', 'of', 'remifentanyl', '05', 'μg/kg', 'and', 'propofol', '2', 'mg/kg'] | [0, 1, 3, 0, 0, 0, 33, 0, 57, 58, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 57, 0, 60, 0, 57, 59, 60] |
| 56 | Muscle paralysis was obtained with Cisatracurium (0.15 μg/kg). | ['B-Disease_disorder', 'I-Disease_disorder', 'O', 'O', 'O', 'B-Medication', 'O', 'I-Dosage'] | ['muscle', 'paralysis', 'was', 'obtained', 'with', 'cisatracurium', '015', 'μg/kg'] | [25, 26, 0, 0, 0, 57, 0, 60] |
| 57 | Transoral intubation was performed with a Macintosh blade (No.3) and a size 7 mm diameter reinforced tracheal tube was easily and gently placed in the trachea, on the first attempt and was then fixed to the right corner of the mouth. | ['B-Detailed_description', 'B-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'B-Detailed_description', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'I-Biological_structure', 'I-Biological_structure'] | ['transoral', 'intubation', 'was', 'performed', 'with', 'a', 'macintosh', 'blade', 'no3', 'and', 'a', 'size', '7', 'mm', 'diameter', 'reinforced', 'tracheal', 'tube', 'was', 'easily', 'and', 'gently', 'placed', 'in', 'the', 'trachea', 'on', 'the', 'first', 'attempt', 'and', 'was', 'then', 'fixed', 'to', 'the', 'right', 'corner', 'of', 'the', 'mouth'] | [13, 33, 0, 0, 0, 0, 33, 34, 0, 0, 0, 0, 13, 14, 14, 13, 33, 34, 0, 0, 0, 0, 0, 0, 0, 11, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 11, 12, 12, 12, 12] |
| 58 | No problems were encountered during laryngoscopy and intubation. | ['O', 'B-Disease_disorder', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'O', 'B-Coreference'] | ['no', 'problems', 'were', 'encountered', 'during', 'laryngoscopy', 'and', 'intubation'] | [0, 25, 0, 0, 0, 33, 0, 29] |
| 59 | The cuff of the tube was inflated with a pressure ≤ 20 cm H2O. | ['O', 'O', 'O', 'O', 'B-Coreference', 'O', 'O', 'O', 'O', 'B-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value', 'I-Lab_value'] | ['the', 'cuff', 'of', 'the', 'tube', 'was', 'inflated', 'with', 'a', 'pressure', '≤', '20', 'cm', 'h2o'] | [0, 0, 0, 0, 29, 0, 0, 0, 0, 23, 24, 24, 24, 24] |
| 60 | No adjustment of cuff volume was made intra-operatively. | ['O', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure', 'I-Therapeutic_procedure', 'I-Therapeutic_procedure', 'O', 'O', 'O'] | ['no', 'adjustment', 'of', 'cuff', 'volume', 'was', 'made', 'intra-operatively'] | [0, 33, 34, 34, 34, 0, 0, 0] |
| 61 | N2O was not used for inhalation anaesthesia. | ['B-Medication', 'O', 'O', 'O', 'O', 'O', 'O'] | ['n2o', 'was', 'not', 'used', 'for', 'inhalation', 'anaesthesia'] | [57, 0, 0, 0, 0, 0, 0] |
| 62 | The throat pack was placed in the pharynx to avoid the passage of blood in the aero-digestive tract. | ['O', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'] | ['the', 'throat', 'pack', 'was', 'placed', 'in', 'the', 'pharynx', 'to', 'avoid', 'the', 'passage', 'of', 'blood', 'in', 'the', 'aero-digestive', 'tract'] | [0, 33, 34, 0, 0, 0, 0, 11, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] |
| 63 | General anaesthesia was maintained with Sevofluorane in oxygen/air and Remifentanyl in continuous infusion 0.25 μg/kg/min. | ['B-Medication', 'I-Medication', 'O', 'O', 'O', 'B-Medication', 'B-Administration', 'I-Administration', 'O', 'B-Medication', 'O', 'B-Administration', 'I-Administration', 'O', 'I-Dosage'] | ['general', 'anaesthesia', 'was', 'maintained', 'with', 'sevofluorane', 'in', 'oxygen/air', 'and', 'remifentanyl', 'in', 'continuous', 'infusion', '025', 'μg/kg/min'] | [57, 58, 0, 0, 0, 57, 63, 64, 0, 57, 0, 63, 64, 0, 60] |
| 64 | Moderate arterial hypotension was maintained with a cuff systolic artery pressure of approximately 90 mmHg. | ['B-Severity', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Lab_value', 'I-Lab_value'] | ['moderate', 'arterial', 'hypotension', 'was', 'maintained', 'with', 'a', 'cuff', 'systolic', 'artery', 'pressure', 'of', 'approximately', '90', 'mmhg'] | [49, 9, 10, 0, 0, 0, 0, 0, 19, 20, 20, 0, 0, 23, 24] |
| 65 | The operation was carried out in a semi-supine position with the head slightly inclined forward and laterally and trunk slightly elevated. | ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure', 'O', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'O', 'O', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description'] | ['the', 'operation', 'was', 'carried', 'out', 'in', 'a', 'semi-supine', 'position', 'with', 'the', 'head', 'slightly', 'inclined', 'forward', 'and', 'laterally', 'and', 'trunk', 'slightly', 'elevated'] | [0, 0, 0, 0, 0, 0, 0, 33, 34, 0, 0, 13, 14, 14, 14, 0, 0, 0, 13, 14, 14] |
| 66 | Duration of the operation was 100 minutes. | ['O', 'O', 'O', 'B-Therapeutic_procedure', 'O', 'B-Duration', 'I-Duration'] | ['duration', 'of', 'the', 'operation', 'was', '100', 'minutes'] | [0, 0, 0, 33, 0, 37, 38] |
| 67 | The patient was extubated, after removal of the throat pack without problems. | ['O', 'O', 'O', 'B-Therapeutic_procedure', 'O', 'O', 'O', 'O', 'B-Therapeutic_procedure', 'I-Therapeutic_procedure', 'O', 'B-Disease_disorder'] | ['the', 'patient', 'was', 'extubated', 'after', 'removal', 'of', 'the', 'throat', 'pack', 'without', 'problems'] | [0, 0, 0, 33, 0, 0, 0, 0, 33, 34, 0, 25] |
| 68 | The following day the patient complained of difficulty in swallowing, dysphonia and hoarseness. | ['O', 'B-Date', 'I-Date', 'O', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'B-Sign_symptom', 'O', 'B-Sign_symptom'] | ['the', 'following', 'day', 'the', 'patient', 'complained', 'of', 'difficulty', 'in', 'swallowing', 'dysphonia', 'and', 'hoarseness'] | [0, 39, 40, 0, 0, 0, 0, 9, 10, 10, 9, 0, 9] |
| 69 | Examination revealed deviation of the tongue to the right side and vocal cord paralysis, expression of hypoglossal and recurrent laryngeal nerve injury without local oedema or haematoma. | ['B-Diagnostic_procedure', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'B-Detailed_description', 'I-Detailed_description', 'O', 'B-Biological_structure', 'I-Biological_structure', 'B-Disease_disorder', 'O', 'O', 'B-Biological_structure', 'O', 'B-Detailed_description', 'B-Biological_structure', 'B-Disease_disorder', 'I-Disease_disorder', 'O', 'B-Detailed_description', 'B-Sign_symptom', 'O', 'B-Sign_symptom'] | ['examination', 'revealed', 'deviation', 'of', 'the', 'tongue', 'to', 'the', 'right', 'side', 'and', 'vocal', 'cord', 'paralysis', 'expression', 'of', 'hypoglossal', 'and', 'recurrent', 'laryngeal', 'nerve', 'injury', 'without', 'local', 'oedema', 'or', 'haematoma'] | [19, 0, 9, 0, 0, 11, 0, 0, 13, 14, 0, 11, 12, 25, 0, 0, 11, 0, 13, 11, 25, 26, 0, 13, 9, 0, 9] |
| 70 | The movements of the pharynx and soft palate were normal. | ['O', 'B-Diagnostic_procedure', 'O', 'O', 'B-Biological_structure', 'O', 'B-Biological_structure', 'I-Biological_structure', 'O', 'B-Lab_value'] | ['the', 'movements', 'of', 'the', 'pharynx', 'and', 'soft', 'palate', 'were', 'normal'] | [0, 19, 0, 0, 11, 0, 11, 12, 0, 23] |
| 71 | Meticulous neurological examination, including also magnetic resonance imaging (MRN) revealed no other evidence of central or cranial nerve involvement. | ['O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Biological_structure', 'O', 'B-Biological_structure', 'B-Sign_symptom', 'I-Sign_symptom'] | ['meticulous', 'neurological', 'examination', 'including', 'also', 'magnetic', 'resonance', 'imaging', 'mrn', 'revealed', 'no', 'other', 'evidence', 'of', 'central', 'or', 'cranial', 'nerve', 'involvement'] | [0, 19, 20, 0, 0, 19, 20, 20, 0, 0, 0, 0, 0, 0, 11, 0, 11, 9, 10] |
| 72 | Conservative management included steroids, vitamins together with speech and swallowing therapy. | ['O', 'O', 'O', 'B-Medication', 'B-Medication', 'O', 'O', 'B-Detailed_description', 'O', 'B-Detailed_description', 'B-Therapeutic_procedure'] | ['conservative', 'management', 'included', 'steroids', 'vitamins', 'together', 'with', 'speech', 'and', 'swallowing', 'therapy'] | [0, 0, 0, 57, 57, 0, 0, 13, 0, 13, 33] |
| 73 | Full recovery of lingual and laryngeal functions was obtained within four months after surgery. | ['B-Outcome', 'I-Outcome', 'O', 'B-Biological_structure', 'O', 'B-Biological_structure', 'B-Diagnostic_procedure', 'O', 'O', 'B-Date', 'I-Date', 'I-Date', 'I-Date', 'O'] | ['full', 'recovery', 'of', 'lingual', 'and', 'laryngeal', 'functions', 'was', 'obtained', 'within', 'four', 'months', 'after', 'surgery'] | [53, 54, 0, 11, 0, 11, 19, 0, 0, 39, 40, 40, 40, 0] |
| 74 | Here, we describe another case in a 60-year-old man from San Francisco who had consumed raw pork while traveling in the Philippines. | ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Age', 'B-Sex', 'O', 'B-Personal_background', 'I-Personal_background', 'O', 'O', 'B-Activity', 'I-Activity', 'I-Activity', 'O', 'B-Activity', 'O', 'O', 'B-Nonbiological_location'] | ['here', 'we', 'describe', 'another', 'case', 'in', 'a', '60-year-old', 'man', 'from', 'san', 'francisco', 'who', 'had', 'consumed', 'raw', 'pork', 'while', 'traveling', 'in', 'the', 'philippines'] | [0, 0, 0, 0, 0, 0, 0, 1, 3, 0, 55, 56, 0, 0, 51, 52, 52, 0, 51, 0, 0, 7] |
| 75 | In June 2003, this man became ill with fever, diaphoresis, headache, nausea, and anorexia. | ['O', 'B-Date', 'I-Date', 'O', 'O', 'O', 'B-Sign_symptom', 'O', 'B-Sign_symptom', 'B-Sign_symptom', 'B-Sign_symptom', 'B-Sign_symptom', 'O', 'B-Sign_symptom'] | ['in', 'june', '2003', 'this', 'man', 'became', 'ill', 'with', 'fever', 'diaphoresis', 'headache', 'nausea', 'and', 'anorexia'] | [0, 39, 40, 0, 0, 0, 9, 0, 9, 9, 9, 9, 0, 9] |
| 76 | He had just returned from a 7-month vacation in the Philippines. | ['O', 'O', 'O', 'B-Activity', 'O', 'O', 'B-Duration', 'B-Activity', 'O', 'O', 'B-Nonbiological_location'] | ['he', 'had', 'just', 'returned', 'from', 'a', '7-month', 'vacation', 'in', 'the', 'philippines'] | [0, 0, 0, 51, 0, 0, 37, 51, 0, 0, 7] |
| 77 | Three days after symptoms onset, his physician prescribed doxycycline. | ['B-Date', 'I-Date', 'I-Date', 'I-Date', 'I-Date', 'O', 'O', 'O', 'B-Medication'] | ['three', 'days', 'after', 'symptoms', 'onset', 'his', 'physician', 'prescribed', 'doxycycline'] | [39, 40, 40, 40, 40, 0, 0, 0, 57] |
| 78 | Symptoms continued and he was admitted to a local hospital 5 days later with a fever of 38.9°C, nuchal rigidity, headache, and general malaise. | ['B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'O', 'B-Clinical_event', 'O', 'O', 'B-Nonbiological_location', 'I-Nonbiological_location', 'B-Date', 'I-Date', 'I-Date', 'O', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'B-Sign_symptom', 'O', 'O', 'B-Sign_symptom'] | ['symptoms', 'continued', 'and', 'he', 'was', 'admitted', 'to', 'a', 'local', 'hospital', '5', 'days', 'later', 'with', 'a', 'fever', 'of', '389°c', 'nuchal', 'rigidity', 'headache', 'and', 'general', 'malaise'] | [9, 10, 0, 0, 0, 5, 0, 0, 7, 8, 39, 40, 40, 0, 0, 9, 0, 0, 9, 10, 9, 0, 0, 9] |
| 79 | The patient described no recent contact with sick persons; past medical history was unremarkable. | ['O', 'O', 'O', 'B-History', 'I-History', 'I-History', 'I-History', 'I-History', 'I-History', 'B-History', 'I-History', 'I-History', 'I-History', 'I-History'] | ['the', 'patient', 'described', 'no', 'recent', 'contact', 'with', 'sick', 'persons', 'past', 'medical', 'history', 'was', 'unremarkable'] | [0, 0, 0, 15, 16, 16, 16, 16, 16, 15, 16, 16, 16, 16] |
| 80 | On physical examination, he was somnolent but fully oriented, with no focal findings on neurologic examination and only slight nuchal rigidity. | ['O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Sign_symptom', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Severity', 'B-Sign_symptom', 'I-Sign_symptom'] | ['on', 'physical', 'examination', 'he', 'was', 'somnolent', 'but', 'fully', 'oriented', 'with', 'no', 'focal', 'findings', 'on', 'neurologic', 'examination', 'and', 'only', 'slight', 'nuchal', 'rigidity'] | [0, 19, 20, 0, 0, 9, 0, 9, 10, 0, 0, 9, 10, 0, 19, 20, 0, 0, 49, 9, 10] |
| 81 | He had a leukocyte count of 21,000/mm3, including 16,400/mm3 neutrophils. | ['O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'B-Diagnostic_procedure'] | ['he', 'had', 'a', 'leukocyte', 'count', 'of', '21000/mm3', 'including', '16400/mm3', 'neutrophils'] | [0, 0, 0, 19, 20, 0, 0, 0, 0, 19] |
| 82 | Cerebrospinal fluid (CSF) showed leukocyte count of 487/μL with 80% polymorphonuclear cells and 18% lymphocytes, and glucose and protein levels <20 mg/dL and <167 mg/dL, respectively. | ['B-Biological_structure', 'I-Biological_structure', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value', 'O', 'O', 'I-Lab_value', 'I-Lab_value', 'O', 'O', 'I-Lab_value', 'O', 'B-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'I-Lab_value', 'O', 'O', 'I-Lab_value', 'O'] | ['cerebrospinal', 'fluid', 'csf', 'showed', 'leukocyte', 'count', 'of', '487/μl', 'with', '80%', 'polymorphonuclear', 'cells', 'and', '18%', 'lymphocytes', 'and', 'glucose', 'and', 'protein', 'levels', '20', 'mg/dl', 'and', '167', 'mg/dl', 'respectively'] | [11, 12, 0, 0, 19, 20, 0, 23, 0, 0, 24, 24, 0, 0, 24, 0, 19, 0, 19, 0, 0, 24, 0, 0, 24, 0] |
| 83 | Gram stain of CSF showed gram-positive cocci in pairs (Figure). | ['B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Biological_structure', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O'] | ['gram', 'stain', 'of', 'csf', 'showed', 'gram-positive', 'cocci', 'in', 'pairs', 'figure'] | [19, 20, 0, 11, 0, 9, 10, 10, 10, 0] |
| 84 | Empiric therapy (ceftriaxone, vancomycin, and ampicillin) for bacterial meningitis was begun. | ['O', 'O', 'O', 'B-Medication', 'O', 'B-Medication', 'O', 'B-Disease_disorder', 'I-Disease_disorder', 'O', 'O'] | ['empiric', 'therapy', 'ceftriaxone', 'vancomycin', 'and', 'ampicillin', 'for', 'bacterial', 'meningitis', 'was', 'begun'] | [0, 0, 0, 57, 0, 57, 0, 25, 26, 0, 0] |
| 85 | Computed tomographic scan of the head showed only sinusitis; findings of chest radiograph and transesophageal echocardiogram were negative. | ['B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'B-Biological_structure', 'O', 'O', 'B-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'B-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value'] | ['computed', 'tomographic', 'scan', 'of', 'the', 'head', 'showed', 'only', 'sinusitis', 'findings', 'of', 'chest', 'radiograph', 'and', 'transesophageal', 'echocardiogram', 'were', 'negative'] | [19, 20, 20, 0, 0, 11, 0, 0, 9, 0, 0, 11, 19, 0, 19, 20, 0, 23] |
| 86 | On hospital day 2, blood cultures grew gram-positive cocci in pairs and chains. | ['O', 'B-Date', 'I-Date', 'I-Date', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'B-Detailed_description', 'O', 'B-Detailed_description'] | ['on', 'hospital', 'day', '2', 'blood', 'cultures', 'grew', 'gram-positive', 'cocci', 'in', 'pairs', 'and', 'chains'] | [0, 39, 40, 40, 19, 20, 0, 9, 10, 0, 13, 0, 13] |
| 87 | The organism was catalase-negative, bile esculin-negative, and pyrrolidonyl aminopeptidase-negative, consistent with Streptococcus spp. | ['O', 'B-Sign_symptom', 'O', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom'] | ['the', 'organism', 'was', 'catalase-negative', 'bile', 'esculin-negative', 'and', 'pyrrolidonyl', 'aminopeptidase-negative', 'consistent', 'with', 'streptococcus', 'spp'] | [0, 9, 0, 0, 19, 0, 0, 19, 0, 0, 0, 9, 10] |
| 88 | A latex agglutination test did not detect Streptococcus pneumoniae antigen. | ['O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['a', 'latex', 'agglutination', 'test', 'did', 'not', 'detect', 'streptococcus', 'pneumoniae', 'antigen'] | [0, 19, 20, 20, 0, 0, 0, 9, 10, 10] |
| 89 | Antimicrobial susceptibility testing showed that the isolate was sensitive to penicillin (MIC = 0.03), ceftriaxone, and vancomycin but resistant to tetracycline and clindamycin. | ['B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'B-Coreference', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'I-Sign_symptom', 'O', 'O', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['antimicrobial', 'susceptibility', 'testing', 'showed', 'that', 'the', 'isolate', 'was', 'sensitive', 'to', 'penicillin', 'mic', '=', '003', 'ceftriaxone', 'and', 'vancomycin', 'but', 'resistant', 'to', 'tetracycline', 'and', 'clindamycin'] | [19, 20, 20, 0, 0, 0, 29, 0, 9, 10, 10, 0, 10, 0, 0, 10, 10, 0, 9, 10, 10, 10, 10] |
| 90 | Antimicrobial therapy was changed to penicillin G, 24 million units intravenously per day. | ['B-Medication', 'I-Medication', 'O', 'O', 'O', 'B-Medication', 'I-Medication', 'B-Dosage', 'I-Dosage', 'I-Dosage', 'B-Administration', 'B-Frequency', 'I-Frequency'] | ['antimicrobial', 'therapy', 'was', 'changed', 'to', 'penicillin', 'g', '24', 'million', 'units', 'intravenously', 'per', 'day'] | [57, 58, 0, 0, 0, 57, 58, 59, 60, 60, 63, 43, 44] |
| 91 | On hospital day 5, the patient complained of hearing loss in his left ear. | ['O', 'B-Date', 'I-Date', 'I-Date', 'O', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'B-Biological_structure', 'I-Biological_structure'] | ['on', 'hospital', 'day', '5', 'the', 'patient', 'complained', 'of', 'hearing', 'loss', 'in', 'his', 'left', 'ear'] | [0, 39, 40, 40, 0, 0, 0, 0, 9, 10, 0, 0, 11, 12] |
| 92 | Results of nasopharyngeal endoscopy were negative. | ['O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value'] | ['results', 'of', 'nasopharyngeal', 'endoscopy', 'were', 'negative'] | [0, 0, 19, 20, 0, 23] |
| 93 | By hospital day 7, the organism was identified by the API 20 Strep System (bioMerieux, Marcy l’Etoile, France), as S. suis serotype 2. | ['O', 'B-Date', 'I-Date', 'I-Date', 'O', 'B-Coreference', 'O', 'O', 'O', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'O', 'O', 'O', 'O', 'O', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom'] | ['by', 'hospital', 'day', '7', 'the', 'organism', 'was', 'identified', 'by', 'the', 'api', '20', 'strep', 'system', 'biomerieux', 'marcy', 'l’etoile', 'france', 'as', 's', 'suis', 'serotype', '2'] | [0, 39, 40, 40, 0, 29, 0, 0, 0, 0, 19, 20, 20, 20, 0, 0, 0, 0, 0, 0, 10, 10, 10] |
| 94 | The patient subsequently stated that he was a butcher with a culinary preference for partially cooked pork, which he had eaten in the Philippines until the week prior to onset of symptoms. | ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Occupation', 'O', 'O', 'B-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Detailed_description', 'I-Other_entity', 'O', 'O', 'O', 'B-Activity', 'O', 'O', 'B-Nonbiological_location', 'B-Date', 'I-Date', 'I-Date', 'I-Date', 'I-Date', 'I-Date', 'I-Date', 'I-Date'] | ['the', 'patient', 'subsequently', 'stated', 'that', 'he', 'was', 'a', 'butcher', 'with', 'a', 'culinary', 'preference', 'for', 'partially', 'cooked', 'pork', 'which', 'he', 'had', 'eaten', 'in', 'the', 'philippines', 'until', 'the', 'week', 'prior', 'to', 'onset', 'of', 'symptoms'] | [0, 0, 0, 0, 0, 0, 0, 0, 65, 0, 0, 13, 14, 14, 14, 14, 68, 0, 0, 0, 51, 0, 0, 7, 39, 40, 40, 40, 40, 40, 40, 40] |
| 95 | On hospital day 9, a formal audiology evaluation showed severe bilateral sensorineural high-frequency hearing loss (–70 dB). | ['O', 'B-Date', 'I-Date', 'I-Date', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Severity', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'I-Lab_value'] | ['on', 'hospital', 'day', '9', 'a', 'formal', 'audiology', 'evaluation', 'showed', 'severe', 'bilateral', 'sensorineural', 'high-frequency', 'hearing', 'loss', '–70', 'db'] | [0, 39, 40, 40, 0, 19, 20, 20, 0, 49, 9, 10, 10, 10, 10, 0, 24] |
| 96 | The patient completed a 10-day course of parenteral antimicrobial drugs and was discharged on continued oral therapy with close followup. | ['O', 'O', 'O', 'O', 'B-Duration', 'I-Duration', 'O', 'B-Medication', 'I-Medication', 'I-Medication', 'O', 'O', 'B-Clinical_event', 'O', 'B-Detailed_description', 'B-Medication', 'I-Medication', 'O', 'O', 'O'] | ['the', 'patient', 'completed', 'a', '10-day', 'course', 'of', 'parenteral', 'antimicrobial', 'drugs', 'and', 'was', 'discharged', 'on', 'continued', 'oral', 'therapy', 'with', 'close', 'followup'] | [0, 0, 0, 0, 37, 38, 0, 57, 58, 58, 0, 0, 5, 0, 13, 57, 58, 0, 0, 0] |
| 97 | Two months after discharge, the patient reported much improved hearing without other sequelae. | ['B-Date', 'I-Date', 'I-Date', 'I-Date', 'O', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'B-Sign_symptom'] | ['two', 'months', 'after', 'discharge', 'the', 'patient', 'reported', 'much', 'improved', 'hearing', 'without', 'other', 'sequelae'] | [39, 40, 40, 40, 0, 0, 0, 9, 10, 10, 0, 0, 9] |
| 98 | A 74-year-old man was referred to our hospital in November 2000 because of liver dysfunction detected during a medical checkup. | ['O', 'B-Age', 'B-Sex', 'O', 'B-Clinical_event', 'O', 'O', 'B-Nonbiological_location', 'O', 'B-Date', 'I-Date', 'O', 'O', 'B-Sign_symptom', 'I-Sign_symptom', 'O', 'O', 'O', 'B-Clinical_event', 'I-Clinical_event'] | ['a', '74-year-old', 'man', 'was', 'referred', 'to', 'our', 'hospital', 'in', 'november', '2000', 'because', 'of', 'liver', 'dysfunction', 'detected', 'during', 'a', 'medical', 'checkup'] | [0, 1, 3, 0, 5, 0, 0, 7, 0, 39, 40, 0, 0, 9, 10, 0, 0, 0, 5, 6] |
| 99 | The patient had been diagnosed with nephrotic syndrome in 1995. | ['O', 'O', 'O', 'O', 'O', 'O', 'B-Disease_disorder', 'I-Disease_disorder', 'O', 'B-Date'] | ['the', 'patient', 'had', 'been', 'diagnosed', 'with', 'nephrotic', 'syndrome', 'in', '1995'] | [0, 0, 0, 0, 0, 0, 25, 26, 0, 39] |
| 100 | Laboratory examinations showed elevated serum hepatobiliary enzymes and IgM, and the presence of antimitochondrial antibodies. | ['B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Lab_value', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure', 'I-Diagnostic_procedure', 'O', 'B-Diagnostic_procedure', 'O', 'O', 'B-Lab_value', 'O', 'B-Diagnostic_procedure', 'I-Diagnostic_procedure'] | ['laboratory', 'examinations', 'showed', 'elevated', 'serum', 'hepatobiliary', 'enzymes', 'and', 'igm', 'and', 'the', 'presence', 'of', 'antimitochondrial', 'antibodies'] | [19, 20, 0, 23, 19, 20, 20, 0, 19, 0, 0, 23, 0, 19, 20] |