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+# SequentialTherapySecondaryThyroidCancer
+The IIP mathematical model is used to estimate the radiation and chemotherapy-induced 
+relative risks of thyroid malignancies in four childhood cancer study survivors (CCSS) data sets. the predictions 
+of radiation and chemotherapy-induced relative risks of secondary thyroid malignancies using the mathematical model 
+are compared against four clinical datasets from the CCSS cohort. Moreover, the extracted average value of growth 
+rate of premalignant cells is 0.8175 (per day) and the extracted chemo-induced mutation rate is of the order of 
+10(−10) (per unit of chemotherapeutic dose).
+
+Manuscript: http://iopscience.iop.org/article/10.1088/2057-1739/aa7dec/meta