Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN); if liver metastases are present, =< 5 x ULNXx_NEWLINE_xXTREATMNET: Aspartate aminotransferase (AST) =< 3 x upper limit of normalXx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3.0 times institutional upper limit of normal with or without liver metastasis, within 21 days prior to study entryXx_NEWLINE_xXAlanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< 1.5 x institutional upper limit of normal (IULN) within 28 days prior to registrationXx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 6 times upper limit of normal (ULN); obtained within 14 days prior to study entryXx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN) within 14 days prior to registrationXx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN) obtained within 2 weeks prior to registrationXx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) within =< 3 x upper limit of normalXx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 2.5 x the upper limit of normalXx_NEWLINE_xXAlanine aminotransferase (ALT) =< 2.5 x the upper limit of institutional normalXx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 2.5 x upper limits of normal (ULN)Xx_NEWLINE_xXAlanine aminotransferase level (ALT) =< 3 x the upper limit of normal (ULN), within 30 days prior to enrollmentXx_NEWLINE_xXObtained =< 48 hours prior to registration: Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 3 x upper limit of normal (ULN)Xx_NEWLINE_xXAlanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< 2.5 times upper limit of normalXx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 3 x the institutional upper limit of normalXx_NEWLINE_xXAspartate aminotransferase (AST) =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXIf liver metastases present, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) must be < 3 x upper limit of normal (ULN)Xx_NEWLINE_xXTransaminases (alanine aminotransferase [ALT], aspartate aminotransferase [AST]) =< 2.5 x institutional upper limit normalXx_NEWLINE_xXLiver transaminases (alanine aminotransferase [ALT], aspartate aminotransferase [AST]) greater than 3 times the upper limit of normalXx_NEWLINE_xXPatients must have aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3.0 x institutional upper limit of normal (IULN) within 14 days prior to registrationXx_NEWLINE_xXSerum aspartate aminotransferase (AST) and serum alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 upper limits of normal (ULN)* Unless due to hepatic metastases in which case levels =< 5 x ULN are allowedXx_NEWLINE_xXWithin 14 days of registration: Aspartate aminotransferase (AST) =< 2.5 x upper limits of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3 x upper limit of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST) or alanine aminotransferase (ALT) =< 3.0 x upper limits of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3.0 upper limit of normal (ULN)Xx_NEWLINE_xXAlanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< 2.5 x institutional upper limit of normal (IULN) (or =< 5 x IULN if liver metastases are present)Xx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3 x upper limit of normal (ULN); if liver metastases, =< 5 x upper limit of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 3 x the upper limit of normalXx_NEWLINE_xXSerum aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) > 3 times upper limit of institutional normalXx_NEWLINE_xXAspartate aminotransferase (AST) / alanine aminotransferase (ALT) =< 2.5 X upper limit of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST) or alanine aminotransferase (ALT) < 1.5 x the upper limit of normalXx_NEWLINE_xXAspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN)Xx_NEWLINE_xXAspartate aminotransferase (AST), alanine aminotransferase (ALT) =< 3 x upper limit of normal (ULN), unless suspected leukemic involvement of the liverXx_NEWLINE_xX