Human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; however, HIV-positive patients without an acquired immune deficiency syndrome (AIDS)-defining diagnosis who are not receiving agents with the potential for pharmacokinetic (PK) interactions with ABT-888 may be eligibleXx_NEWLINE_xXKnown human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are not eligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXKnown human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXKnown human immunodeficiency virus (HIV) or other history of immunodeficiency disorder; HIV-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHIV-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHIV-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV) positive patients on antiretroviral therapy are ineligibleXx_NEWLINE_xXTREATMENT: HIV-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; it is not necessary to conduct HIV testing at screening; patients who are HIV-positive with undetectable viral loads, not on interacting antiretroviral therapy, and have CD4 counts above 300/mm^3 may be eligible after discussion with the principal investigatorXx_NEWLINE_xXHIV-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXPatients known to be human immunodeficiency virus (HIV)-positive patients and on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHIV-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive subjects on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXPatients who are known to have human immunodeficiency virus (HIV) or are on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXPatients who are known to have human immunodeficiency virus (HIV) or are on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXPatient does not have known human immunodeficiency virus syndrome (HIV, testing optional); known HIV-positive patients receiving combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy known to interact with CYP isoenzymes are ineligible; in addition, HIV patients with CD4 count < 200 cells/uL are ineligible; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicatedXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXPatients with human immunodeficiency virus (HIV) on antiretroviral therapy are ineligibleXx_NEWLINE_xXPatients who are known to be human immunodeficiency positive (HIV)-positive and are on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicatedXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicatedXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive subjects on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; patients must also have a CD4 count > 350 cells/mm^3 with an undetectable viral loadXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicatedXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients are ineligible; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicatedXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are INELIGIBLEXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicatedXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligibleXx_NEWLINE_xXHuman immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible due to potential drug-drug interactions with PT2385Xx_NEWLINE_xX