Patients known to have one of the following concomitant genetic syndromes: Down syndrome, Bloom syndrome, ataxia-telangiectasia, Fanconi anemia, Kostmann syndrome, Shwachman syndrome or any other known bone marrow failure syndromeXx_NEWLINE_xXPatients with any of the following diagnoses:* Acute promyelocytic leukemia (APL)* Down syndrome* Fanconi anemia, Kostmann syndrome, Shwachman syndrome or any other known bone marrow failure syndrome* Wilson's disease and any other disorder of copper metabolism* Juvenile myelomonocytic leukemia (JMML)Xx_NEWLINE_xXPatients known to have one of the following concomitant genetic syndromes: Bloom syndrome, ataxia-telangiectasia, Fanconi anemia, Kostmann syndrome, Shwachman syndrome, or any other known bone marrow failure syndromeXx_NEWLINE_xXPatients with known symptomatic Fanconi anemia (FA), ataxia-telangiectasia (A-T) syndrome, Bloom syndrome (BS) and Nijmegen breakage syndrome (NBS) are not eligible (asymptomatic carriers are acceptable)Xx_NEWLINE_xX