Platelet count >= 100,000/mm�Xx_NEWLINE_xXPlatelet (PLTs) count >= 100,000/mm^3 obtained =< 21 days prior to registrationXx_NEWLINE_xXPlatelet count >= 100,000 cells/mcLXx_NEWLINE_xXPeripheral platelet count (PLT) >= 75,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count > 100,000Xx_NEWLINE_xXPlatelet count >= 100,000/mL within 28 days prior to registrationXx_NEWLINE_xXSTEP I: Untransfused platelet count >= 75,000 cells/mm^3 (obtained within 28 days prior to randomization)Xx_NEWLINE_xXPlatelet count < 100 x 10^9/LXx_NEWLINE_xXPlatelet count > 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 50 x 10^9/LXx_NEWLINE_xXPlatelet count >= 75,000/mm^3 within 90 days prior to randomizationXx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000 mcl obtained within 28 days prior to sub-study registrationXx_NEWLINE_xXPlatelet count >= 100 x 10^9/LXx_NEWLINE_xXPlatelet count >= 100 x 10^9/L measured within 28 days prior to randomizationXx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mcLXx_NEWLINE_xXPatients on Part C with acute lymphoblastic leukemia: platelet count >= 20,000/mm^3 (may receive platelet transfusions); these patients must not be known to be refractory to red cell or platelet transfusionXx_NEWLINE_xXPlatelet count > 50,000/mm^3Xx_NEWLINE_xXPlatelet count >= 75,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXWithin 6 weeks prior to randomization: Platelet count must be >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXRe-registration: platelet count >= 100,000/mm^3Xx_NEWLINE_xXWithin 14 days of registration: Platelet count >= 75,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 75,000/mcL; must be obtained within 28 days prior to registrationXx_NEWLINE_xXPlatelet count >= 100,000/ mL within 21 days prior to registrationXx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXCLINICAL/LABORATORY CRITERIA: Platelet count >= 100,000/mcL; these results must be obtained within 28 days prior to registrationXx_NEWLINE_xXPlatelet count must be >= 100,000/mm^3 within 28 days before randomizationXx_NEWLINE_xXPlatelet count >= 100,000/mm^3, within 4 weeks of randomizationXx_NEWLINE_xXPlatelet count >= 100,000/mm^3Xx_NEWLINE_xXPlatelet count >= 100,000 mm^3; platelets >= 75,000 required for patients who received cycle 1 of mFOLFOX6 prior to registrationXx_NEWLINE_xXPlatelet count < 100 x 10^9/LXx_NEWLINE_xXPlatelet count >= 75,000/mm^3Xx_NEWLINE_xX