Not participating in another weight loss, physical activity or dietary intervention clinical trial; co-enrollment in some trials involving pharmacologic therapy is allowed; participants in both arms are also allowed to pursue weight loss and physical activity programs on their own, as long as these programs are not provided as part of a clinical trial
Experienced weight loss > 10% over approximately 2 months prior to first dose of study therapy
>10% weight loss over the 28 days prior to consent.
Unintentional weight loss > 10% within 30 days prior to registration
> 10% unintentional weight loss within the past month
Unintentional weight loss >10% within 4 weeks prior to study registration.
Significant weight loss (> 20% of body weight) within past 6 months prior to inclusion into the trial
Participation in a diet (Atkins, Weight Watchers, Best Life, Nutrisystem, South Beach, Jenny Craig, Paleo Diet, Zone etc) or weight loss plan within 28 days prior to day 1 of treatment
Has experienced weight loss > 10% over 2 months prior to first dose of study therapy
Weight loss of > 10% in the past 6 months
Weight loss < 10% in preceding 3 months prior to diagnosis
Recent history of unintentional weight loss > 10% of current body weight in the past 3 months.
Patients that have experienced an involuntary weight loss of more than 25% of their body weight in the 2 months preceding study entry
No systemic or B symptoms (fever >38°C for 3 consecutive days; recurrent, drenching night sweats; unintentional weight loss exceeding 10% body weight in the last 6 months.
Significant weight loss (> 10% of body weight [BW]) within past 6 months prior to inclusion into the trial
Weight loss of > 10% over the past 6 months which is due to tumor wasting syndrome
History/physical examination within 4 weeks prior to registration, including assessment of weight and weight loss in past 6 months
Weight loss < 15% in the 3 months before diagnosis
Weight > 12 kilograms
Subjects with recent significant or unexplained weight loss that the investigator feels may pose an unacceptable risk for enrollment; candidates who are overweight and have lost weight intentionally via diet or exercise should not be excluded, for instance
Patients that have experienced an involuntary weight loss of more than 25% of their body weight in the 2 months preceding study entry
Patients with >= 10% weight loss within the past month
Unintentional weight loss >= 5% of body weight within the past 6 months
Patients must not have more than 10% weight loss in the past 6 months
unintentional weight loss of 10% or more within the previous 6 months
Unintended weight loss >10% in 6 months preceding study entry.
Patients with weight loss =< 10% over the past 3 months
Unintentional weight loss >= 10% in the last 3 months (mos)
10% weight loss within the past month
Currently actively involved in another diet intervention study or organized weight loss program
Significant weight loss (> 10%) in the prior 3 months
Serious/uncontrolled medical condition, at the discretion of the protocol chair/designee, likely to hinder accurate measurement of weight, including any condition: for which weight loss is contraindicated, which would likely cause weight loss, or which would affect adipokine and inflammatory markers (e.g., other active malignancy, end stage renal disease [ESRD] on dialysis, cirrhosis, autoimmune disease, adrenal disease, and history of bariatric surgery)
Currently enrolled or planning to enroll in a weight loss program (e.g., Innergy, Weight Watchers, Jenny Craig, Nutrisystem, and Medifast); participants also agree not to enroll in such a program for the duration of study participation (regardless of randomization)
Patients that have experienced an involuntary weight loss of more than 25% of their body weight in the 2 months preceding study entry
Patient's nutritional and general physical condition must be considered compatible with the proposed radiotherapeutic treatment (cannot have unintentional and/or surgically unrelated weight loss > 20% in the preceding 3 months); this assessment is a standard of care assessment for this patient population; this requirement can be waived by the investigator if the subject has an identifiable procedure which is the immediate and sole cause for the weight loss without an underlying pathological cause; an example of a situation like this would be if a participant is found to need a tonsillectomy during the pretreatment evaluations; it’s obvious that this scenario would be a non-pathological reason for such a weight loss; the Principal Investigator (PI) will only have this ability to waive this criterion if and only if he can substantiate and document that the weight loss does not have a pathological etiology and will correct itself within a reasonable and acceptable period of time
More than 10% weight loss in 6 months, given the poor prognostic sign of significant weight loss, and the possible intolerance to combined modality therapy
Absence of combined 1p/19q loss
Ability to maintain their weight
Evidence of active hair loss
Significant weight loss (> 10% of body weight [BW]) within past 6 months prior to inclusion into the trial
Weight loss >20% in the previous 6 months.
Current (within 3 months of study commencement) use of weight loss medication(s)
History of weight loss surgery
Weight loss =< 5% in the previous six months unless weight loss is intentional (per judgment of study medical doctor [MD])
Significant cancer-related weight loss (?10%)within four weeks prior to treatment start
Unexplained weight loss exceeding 10% of body weight over the previous 6 months.
Unintentional weight loss (10% within the previous 6 months)
weight loss of greater than 10% within the prior 6 months
Significant weight loss (> 10 %) within the past 6 weeks prior to treatment in the present trial
Mild cancer cachexia, determined as a proxy screening strategy, by an Eastern Cooperative Oncology Group (ECOG) performance status of =< 2 and a history of mild to moderate weight loss (i.e. =< 10% loss of patient reported usual body weight (pre-cancer diagnosis); patients may also be eligible without a history of weight loss if their treating physician identifies mild cancer cachexia associated with a non-cancer related diagnosis (e.g. chronic obstructive pulmonary disease [COPD], etc.) and meets ECOG criteria
Presence of unintentional weight loss ranging from >= 2 - =< 15% in last 12 months
Patient is taking medications or supplements for weight loss currently or within the past 3 months
Weight loss of greater than 5% in the previous 6 months
Current, recent (< 1 year), or planning to join a weight loss program or take appetite suppressants
Active blood loss
Weight of < 205 kgs
Weight of < 205 kgs
Weight change > 5% within 3 months of enrollment
Presence of cancer-related cachexia defined as an involuntary weight loss of at least 5% of the pre-illness body weight over the previous 6 months
Participation in other diet-based weight loss programs (i.e. Patient should not be currently enrolled in Weight Watchers, Jenny Craig, Nutrisystem, etc.)
Current use of commercial or natural/herbal weight loss supplements
Must not be participating in another formal weight loss program
Enrollment in a structured weight loss program in the past 6 months
Weight loss =< 10% in 3 months prior to diagnosis
Patients enrolled in a weight loss program or who are taking weight loss medications or dietary supplements and are unwilling to discontinue
Use of metformin, insulin, steroids or prescription weight loss or anti-psychotic drugs within the prior 3 weeks
Participation within the past 6 months on a structured weight loss program such as Weight Watchers®
Use of metformin, insulin, steroids or weight loss or anti-psychotic drugs within the prior 3 weeks
Participation within the past 6 months on a structured weight loss program such as Weight Watchers
Involvement in a weight loss program
Weight loss greater than 10% in prior 4 weeks
Weight < 205 kilograms
Currently enrolled or planned to enroll in weight loss program
Use of prescription weight loss medication(s) (e.g., lorcaserin, topiramate/phentermine, phentermine, liraglutide, and bupropion/naltrexone), including off label use of drugs for weight loss or over-the-counter weigh loss medications such as Orlistat within the past 6 months
Are on a weight loss program
Currently involved in a supervised program for weight loss
Use of insulin or other diabetes medications that would require additional medical monitoring during weight-loss; use of medications for weight loss or that may impact weight or glucometabolic function (e.g. corticosteroids)
Serious medical conditions where weight loss is contraindicated
Participants who are already enrolled in, or planning to enroll in another research study where weight loss is targeted will be excluded
Subjects who are part of any structured weight loss programs (e.g. Weight Watchers, etc.) are not eligible
Current use of weight loss medications including herbal weight loss supplements or enrolled in a diet/weight loss program
Weight loss > 5% of body weight in the last 6 months based on self-report
Must be weight stable, as defined by staying within 10 percent of their current weight for 6 months
Current participation in a weight-loss program
Currently actively involved in another diet intervention study or organized weight loss program
Experienced unexplained weight loss of 15-pounds or more during six months prior to enrollment
Use of any antidiabetic, weight loss, or appetite control medication